GREMLIN Database
Uncharacterized membrane protein YhhNLast updated: 1425931314

Organism: ECOLI    
Function: unknown
Type: MEM
Uniprot: P0ADI9
Ecogene: EG12214
Pfam: PF07947 YhhN
Co-evolution data: 1423539070



Notes:
  • Model is very good.
Contact map:
Note from Yuxing Liao:
  • Some yhhN proteins are shown to be lysoplasmalogenases (PMID: 25445671, 21515882). The first paper is just published and suggests some potential catalytic residues based on alignments and conservation. These residues, i.e. K31, D66, H87, S171, Y195 indeed form a pocket in the core of the model. The invariant D66 might be the trigger of the reaction, like the only other enzyme that hydrolyzes the vinyl ether bond, PhzD (PDB: 1NF9, not homologous).
  • In ECOD, it might be a new X-group, although structural search finds a bunch of GPCR rhodopsins.

Models
Name DB Rc Date Action
Model P0ADI9_ECOLI 0.935 06Jan2015 View - Download
Model P0ADI9_ECOLI 0.926 06Jan2015 View - Download
Model P0ADI9_ECOLI 0.920 06Jan2015 View - Download
Model P0ADI9_ECOLI 0.919 06Jan2015 View - Download
Model P0ADI9_ECOLI 0.917 06Jan2015 View - Download
Files
File
YHHN_models.png
YHHN_06Jan2015.zip
YHHN_contacts-fs8.png

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