GREMLIN Database
PF02538 - N-methylhydantoinase B (HyuB-3)
UniProt: Q97UR7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 508 (508)
Sequences: 8564 (5536)
Seq/√Len: 245.6
META: 0.852

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
412_T437_R4.4131.00
252_G302_K4.3941.00
74_E149_K4.0181.00
254_Y304_D3.6551.00
229_D336_K3.6061.00
258_A304_D3.4081.00
254_Y302_K3.3711.00
212_K299_S3.2671.00
307_K314_N3.1621.00
224_N250_E3.0481.00
381_N426_Y3.0021.00
40_D44_N2.9771.00
73_L79_I2.9731.00
226_I247_K2.9171.00
468_K498_E2.9061.00
228_E245_K2.7771.00
226_I245_K2.7191.00
230_E243_R2.5531.00
212_K216_L2.5481.00
148_R153_N2.5361.00
413_I435_A2.4891.00
435_A496_I2.3991.00
145_R148_R2.3651.00
209_E299_S2.3651.00
98_A181_N2.3291.00
230_E241_K2.3171.00
263_Q317_A2.3121.00
228_E243_R2.2881.00
100_V110_V2.2731.00
241_K261_D2.1731.00
227_G341_L2.1521.00
379_R382_K2.1271.00
272_Y305_A2.0981.00
154_N158_N2.0841.00
454_A466_P2.0631.00
74_E148_R2.0481.00
437_R494_E2.0481.00
262_T306_P2.0451.00
102_Y193_D2.0241.00
410_M439_L2.0241.00
220_S251_N1.9971.00
133_T136_E1.9881.00
383_D427_K1.9871.00
260_T310_I1.9821.00
386_S430_D1.9611.00
156_I159_I1.9551.00
69_Q158_N1.9491.00
413_I433_I1.9401.00
80_V94_V1.9101.00
105_N201_L1.8981.00
244_L255_A1.8971.00
187_R190_Q1.8851.00
423_V462_G1.8731.00
103_N193_D1.8501.00
192_F200_V1.8401.00
107_M192_F1.8361.00
433_I498_E1.8271.00
472_I493_D1.8251.00
435_A494_E1.8191.00
468_K480_E1.7971.00
473_R479_E1.7921.00
490_N493_D1.7891.00
255_A279_V1.7881.00
305_A312_N1.7871.00
122_P130_Y1.7851.00
242_I333_V1.7781.00
259_G306_P1.7641.00
73_L109_Y1.7641.00
412_T494_E1.7631.00
441_K491_K1.7621.00
470_T478_K1.7571.00
441_K490_N1.7451.00
105_N197_Y1.7401.00
216_L252_G1.7271.00
4_I203_A1.7251.00
122_P136_E1.7241.00
387_A416_I1.7231.00
75_E104_G1.7101.00
112_N181_N1.7031.00
415_R433_I1.7001.00
412_T435_A1.7001.00
98_A185_I1.6891.00
132_T136_E1.6881.00
46_I204_W1.6851.00
44_N64_K1.6761.00
141_I159_I1.6741.00
305_A311_V1.6731.00
14_E187_R1.6661.00
185_I189_K1.6551.00
189_K193_D1.6541.00
410_M437_R1.6321.00
212_K300_L1.6321.00
218_E221_K1.6311.00
473_R493_D1.6161.00
116_Q177_Q1.5951.00
197_Y201_L1.5931.00
65_N68_N1.5911.00
456_W463_N1.5901.00
257_F279_V1.5861.00
148_R155_E1.5851.00
44_N295_E1.5821.00
282_V334_T1.5821.00
153_N156_I1.5781.00
94_V119_V1.5771.00
306_P312_N1.5741.00
44_N205_K1.5581.00
192_F197_Y1.5361.00
232_Y241_K1.5351.00
438_V442_T1.5341.00
44_N299_S1.5341.00
208_M299_S1.5331.00
247_K254_Y1.5251.00
41_A201_L1.5231.00
285_S335_F1.5231.00
7_A194_K1.5231.00
79_I145_R1.5131.00
102_Y192_F1.5071.00
248_V253_V1.5011.00
262_T309_T1.4821.00
224_N248_V1.4811.00
147_M178_I1.4781.00
140_V315_K1.4751.00
416_I430_D1.4721.00
417_R465_K1.4661.00
276_F303_V1.4631.00
78_M98_A1.4621.00
239_L453_V1.4561.00
152_I157_I1.4481.00
307_K312_N1.4441.00
376_T390_V1.4351.00
272_Y312_N1.4311.00
182_L185_I1.4241.00
158_N161_K1.4191.00
75_E189_K1.4181.00
216_L251_N1.4161.00
144_V156_I1.4071.00
347_A456_W1.4061.00
135_Y315_K1.4041.00
253_V283_I1.4001.00
42_E205_K1.3991.00
423_V427_K1.3961.00
272_Y276_F1.3901.00
224_N251_N1.3861.00
448_A469_V1.3801.00
283_I301_I1.3791.00
417_R498_E1.3771.00
376_T385_V1.3701.00
472_I496_I1.3631.00
220_S250_E1.3581.00
102_Y189_K1.3491.00
102_Y107_M1.3471.00
217_S220_S1.3461.00
245_K259_G1.3431.00
443_R488_I1.3431.00
161_K171_I1.3411.00
28_I114_A1.3401.00
100_V185_I1.3331.00
64_K68_N1.3331.00
67_L109_Y1.3311.00
171_I175_N1.3281.00
148_R151_E1.3221.00
482_P485_F1.3201.00
147_M152_I1.3161.00
417_R433_I1.3101.00
78_M178_I1.3091.00
472_I478_K1.3041.00
421_G430_D1.2991.00
100_V188_I1.2891.00
85_Y316_P1.2841.00
16_G51_H1.2781.00
472_I475_D1.2781.00
75_E185_I1.2761.00
246_V255_A1.2711.00
61_I276_F1.2711.00
222_W248_V1.2701.00
257_F330_I1.2621.00
231_D450_R1.2591.00
470_T496_I1.2581.00
98_A182_L1.2581.00
263_Q308_G1.2531.00
474_A493_D1.2531.00
78_M181_N1.2481.00
216_L300_L1.2431.00
471_I489_L1.2401.00
417_R420_S1.2351.00
306_P309_T1.2291.00
308_G314_N1.2291.00
224_N249_D1.2171.00
467_A500_P1.2111.00
224_N227_G1.2101.00
205_K209_E1.2101.00
156_I161_K1.2081.00
15_M184_G1.2031.00
363_G440_E1.1971.00
44_N208_M1.1931.00
258_A306_P1.1881.00
219_I248_V1.1881.00
213_K217_S1.1871.00
183_N186_A1.1871.00
336_K456_W1.1861.00
373_G432_I1.1851.00
132_T265_E1.1761.00
359_G366_W1.1751.00
438_V489_L1.1721.00
182_L186_A1.1711.00
206_T209_E1.1691.00
2_E5_Y1.1651.00
387_A432_I1.1581.00
419_N430_D1.1551.00
418_E430_D1.1551.00
454_A463_N1.1501.00
400_I411_F1.1481.00
222_W342_I1.1381.00
474_A490_N1.1351.00
449_E484_K1.1331.00
200_V204_W1.1331.00
433_I496_I1.1311.00
240_K264_M1.1301.00
459_K505_Y1.1291.00
227_G248_V1.1261.00
397_N414_Y1.1241.00
152_I175_N1.1241.00
222_W227_G1.1211.00
470_T498_E1.1151.00
472_I494_E1.1061.00
35_S55_H1.1061.00
346_A458_L1.1041.00
214_L288_G1.1031.00
263_Q314_N1.0981.00
462_G508_P1.0971.00
229_D456_W1.0951.00
232_Y453_V1.0911.00
267_P318_A1.0871.00
77_D145_R1.0791.00
11_I191_M1.0791.00
309_T312_N1.0741.00
80_V96_V1.0741.00
231_D329_R1.0701.00
74_E145_R1.0611.00
38_I110_V1.0601.00
231_D333_V1.0571.00
94_V116_Q1.0561.00
252_G300_L1.0541.00
107_M197_Y1.0511.00
186_A190_Q1.0501.00
110_V184_G1.0451.00
355_V495_I1.0441.00
20_K34_H1.0391.00
349_S374_G1.0381.00
78_M147_M1.0371.00
206_T210_Y1.0301.00
161_K168_E1.0291.00
7_A191_M1.0271.00
472_I476_G1.0261.00
139_F160_I1.0251.00
66_T79_I1.0221.00
311_V330_I1.0221.00
260_T311_V1.0201.00
441_K488_I1.0201.00
134_I140_V1.0151.00
411_F436_F1.0141.00
64_K295_E1.0091.00
240_K310_I1.0091.00
419_N423_V1.0081.00
255_A334_T1.0071.00
347_A350_G0.9991.00
238_E261_D0.9971.00
229_D333_V0.9951.00
4_I8_S0.9951.00
230_E239_L0.9951.00
213_K251_N0.9931.00
17_V20_K0.9901.00
209_E213_K0.9871.00
275_T305_A0.9821.00
144_V159_I0.9811.00
206_T213_K0.9751.00
83_D140_V0.9731.00
18_M183_N0.9651.00
78_M96_V0.9621.00
106_L109_Y0.9611.00
437_R492_G0.9611.00
256_N304_D0.9601.00
102_Y106_L0.9581.00
247_K250_E0.9571.00
427_K430_D0.9551.00
69_Q86_T0.9501.00
83_D142_P0.9501.00
264_M268_L0.9501.00
226_I249_D0.9501.00
473_R490_N0.9471.00
248_V251_N0.9451.00
249_D254_Y0.9391.00
189_K192_F0.9371.00
108_G200_V0.9371.00
145_R149_K0.9271.00
232_Y239_L0.9251.00
295_E299_S0.9221.00
190_Q193_D0.9191.00
255_A283_I0.9191.00
146_L178_I0.9161.00
233_L268_L0.9161.00
470_T480_E0.9161.00
80_V146_L0.9141.00
100_V189_K0.9131.00
281_F391_N0.9131.00
73_L106_L0.9101.00
112_N180_A0.9081.00
332_D450_R0.9021.00
222_W341_L0.9011.00
63_V97_L0.9001.00
217_S221_K0.8961.00
243_R259_G0.8901.00
240_K261_D0.8891.00
239_L452_R0.8881.00
246_V337_A0.8871.00
361_Y364_K0.8861.00
235_I264_M0.8851.00
443_R486_S0.8841.00
354_N369_Y0.8831.00
145_R153_N0.8821.00
444_L489_L0.8801.00
80_V160_I0.8791.00
232_Y452_R0.8770.99
70_I143_P0.8770.99
471_I487_T0.8760.99
66_T97_L0.8760.99
255_A301_I0.8760.99
152_I171_I0.8750.99
157_I171_I0.8740.99
20_K32_M0.8740.99
236_G266_G0.8730.99
325_E351_T0.8710.99
471_I493_D0.8700.99
211_G215_A0.8700.99
128_N131_A0.8660.99
80_V141_I0.8660.99
83_D86_T0.8650.99
370_E434_R0.8640.99
164_F167_P0.8630.99
144_V153_N0.8590.99
141_I160_I0.8580.99
336_K347_A0.8570.99
102_Y197_Y0.8560.99
438_V495_I0.8550.99
100_V108_G0.8550.99
202_N206_T0.8530.99
239_L261_D0.8500.99
357_M442_T0.8490.99
329_R449_E0.8490.99
107_M201_L0.8460.99
41_A106_L0.8450.99
313_P317_A0.8430.99
41_A105_N0.8430.99
65_N69_Q0.8430.99
158_N168_E0.8430.99
355_V444_L0.8350.99
435_A472_I0.8350.99
280_S298_Y0.8340.99
363_G366_W0.8340.99
208_M295_E0.8330.99
183_N187_R0.8320.99
61_I273_G0.8280.99
417_R431_G0.8230.99
378_A427_K0.8230.99
190_Q194_K0.8230.99
355_V436_F0.8220.99
403_A411_F0.8220.99
383_D426_Y0.8220.99
379_R385_V0.8200.99
235_I238_E0.8200.99
372_I497_I0.8180.99
260_T309_T0.8180.99
224_N252_G0.8170.99
112_N177_Q0.8150.99
2_E6_K0.8120.99
68_N86_T0.8110.99
249_D252_G0.8110.99
168_E364_K0.8110.99
366_W442_T0.8100.99
481_M485_F0.8090.99
283_I338_L0.8080.99
209_E212_K0.8030.99
471_I481_M0.8020.99
380_P505_Y0.8020.99
339_S458_L0.8010.99
80_V144_V0.8000.99
444_L495_I0.7970.99
199_N203_A0.7960.99
97_L109_Y0.7950.99
103_N189_K0.7930.99
271_V313_P0.7930.99
474_A478_K0.7910.99
75_E149_K0.7900.99
60_S295_E0.7890.99
139_F163_N0.7880.99
96_V181_N0.7870.99
381_N425_K0.7850.99
380_P426_Y0.7830.99
421_G464_G0.7810.99
96_V174_L0.7800.99
62_G81_L0.7780.99
155_E158_N0.7770.99
146_L157_I0.7740.99
27_N31_R0.7720.99
264_M310_I0.7710.99
489_L493_D0.7690.99
244_L337_A0.7690.99
154_N171_I0.7680.99
476_G479_E0.7670.99
130_Y486_S0.7630.99
70_I79_I0.7620.99
228_E241_K0.7610.99
212_K252_G0.7600.99
272_Y275_T0.7570.99
101_Y106_L0.7560.99
425_K507_T0.7550.98
471_I479_E0.7550.98
139_F159_I0.7500.98
211_G294_N0.7490.98
365_Y440_E0.7480.98
336_K340_H0.7410.98
210_Y214_L0.7380.98
473_R477_R0.7380.98
257_F311_V0.7370.98
24_M172_G0.7370.98
373_G389_Q0.7340.98
366_W440_E0.7330.98
321_G447_I0.7320.98
155_E159_I0.7310.98
221_K224_N0.7290.98
475_D478_K0.7290.98
159_I163_N0.7280.98
61_I64_K0.7250.98
446_I469_V0.7240.98
39_T63_V0.7240.98
196_G199_N0.7230.98
94_V141_I0.7230.98
444_L487_T0.7220.98
345_P348_G0.7220.98
420_S430_D0.7200.98
98_A112_N0.7180.98
141_I144_V0.7180.98
199_N202_N0.7170.98
75_E101_Y0.7170.98
215_A297_F0.7160.98
119_V164_F0.7150.98
233_L449_E0.7140.98
314_N317_A0.7130.98
42_E201_L0.7130.98
40_D208_M0.7120.98
278_A327_S0.7120.98
278_A331_A0.7110.98
474_A477_R0.7100.98
96_V178_I0.7090.98
181_N185_I0.7090.98
198_D202_N0.7080.98
244_L257_F0.7080.98
473_R476_G0.7050.98
131_A318_A0.7050.98
100_V184_G0.7020.98
244_L333_V0.7020.98
471_I495_I0.7020.98
435_A498_E0.7020.98
87_S92_N0.7010.98
489_L495_I0.7000.98
349_S353_M0.7000.98
305_A308_G0.6990.98
166_V169_V0.6980.97
210_Y213_K0.6980.97
127_L324_V0.6980.97
164_F170_S0.6970.97
378_A381_N0.6960.97
72_E154_N0.6960.97
105_N108_G0.6940.97
97_L111_V0.6930.97
332_D350_G0.6930.97
270_A274_V0.6930.97
238_E264_M0.6920.97
191_M195_Y0.6920.97
453_V466_P0.6890.97
119_V126_S0.6880.97
86_T162_H0.6870.97
77_D149_K0.6860.97
372_I432_I0.6850.97
274_V327_S0.6850.97
257_F260_T0.6830.97
286_L344_V0.6820.97
237_D452_R0.6820.97
134_I316_P0.6800.97
94_V174_L0.6790.97
122_P128_N0.6790.97
414_Y434_R0.6780.97
279_V303_V0.6740.97
346_A349_S0.6740.97
272_Y307_K0.6740.97
39_T111_V0.6700.97
8_S200_V0.6700.97
39_T59_F0.6690.97
108_G204_W0.6690.97
19_L114_A0.6690.97
229_D337_A0.6690.97
442_T489_L0.6680.97
216_L224_N0.6680.97
144_V155_E0.6680.97
462_G504_G0.6680.97
1_W206_T0.6670.97
357_M438_V0.6660.97
246_V253_V0.6650.97
58_S89_T0.6620.97
420_S501_G0.6610.97
5_Y9_E0.6580.96
360_M363_G0.6570.96
402_I406_Y0.6570.96
127_L320_G0.6560.96
258_A309_T0.6540.96
116_Q174_L0.6540.96
374_G377_G0.6530.96
304_D307_K0.6530.96
134_I315_K0.6530.96
75_E102_Y0.6500.96
142_P162_H0.6500.96
16_G34_H0.6500.96
462_G507_T0.6480.96
473_R478_K0.6480.96
243_R258_A0.6480.96
214_L217_S0.6480.96
338_L341_L0.6480.96
216_L250_E0.6470.96
450_R455_P0.6470.96
389_Q393_T0.6460.96
45_I48_Q0.6460.96
69_Q154_N0.6440.96
46_I208_M0.6440.96
140_V162_H0.6430.96
211_G297_F0.6420.96
122_P131_A0.6410.96
260_T306_P0.6410.96
225_G341_L0.6380.96
400_I414_Y0.6370.96
291_I297_F0.6350.96
339_S459_K0.6350.96
479_E487_T0.6350.96
373_G387_A0.6340.96
379_R426_Y0.6340.96
43_G67_L0.6330.96
146_L152_I0.6330.96
147_M150_G0.6320.96
15_M36_C0.6310.95
351_T500_P0.6300.95
472_I477_R0.6300.95
420_S465_K0.6300.95
270_A275_T0.6290.95
270_A313_P0.6290.95
4_I7_A0.6280.95
142_P159_I0.6270.95
263_Q309_T0.6260.95
215_A300_L0.6240.95
91_L138_G0.6230.95
38_I100_V0.6230.95
19_L180_A0.6230.95
205_K208_M0.6220.95
117_V170_S0.6220.95
297_F300_L0.6220.95
229_D244_L0.6180.95
129_P445_S0.6170.95
55_H58_S0.6170.95
91_L119_V0.6170.95
83_D134_I0.6150.95
7_A11_I0.6150.95
235_I266_G0.6140.95
218_E287_I0.6130.95
178_I182_L0.6110.95
146_L174_L0.6100.95
259_G305_A0.6080.94
62_G95_M0.6070.94
37_A59_F0.6070.94
268_L318_A0.6070.94
245_K254_Y0.6050.94
18_M22_S0.6040.94
219_I253_V0.6030.94
465_K498_E0.6030.94
95_M113_K0.6030.94
102_Y105_N0.6020.94
271_V319_V0.6020.94
358_G361_Y0.6020.94
270_A330_I0.6000.94
147_M157_I0.5990.94
119_V139_F0.5990.94
423_V508_P0.5990.94
123_M128_N0.5990.94
150_G182_L0.5980.94
353_M467_A0.5960.94
161_K164_F0.5950.94
135_Y163_N0.5950.94
284_R289_K0.5940.94
186_A193_D0.5940.94
11_I38_I0.5930.94
348_G376_T0.5930.94
208_M211_G0.5930.94
188_I192_F0.5920.94
457_G463_N0.5920.94
19_L112_N0.5910.94
39_T45_I0.5900.94
228_E259_G0.5890.94
478_K496_I0.5890.94
84_P319_V0.5890.94
105_N198_D0.5880.93
229_D347_A0.5880.93
17_V21_R0.5880.93
243_R260_T0.5870.93
368_Y436_F0.5840.93
3_I7_A0.5840.93
186_A189_K0.5830.93
402_I405_R0.5830.93
54_V278_A0.5820.93
8_S204_W0.5790.93
191_M200_V0.5790.93
231_D336_K0.5790.93
337_A340_H0.5790.93
458_L505_Y0.5790.93
382_K426_Y0.5780.93
457_G461_G0.5770.93
203_A206_T0.5770.93
445_S486_S0.5760.93
235_I452_R0.5750.93
66_T70_I0.5750.93
242_I330_I0.5750.93
153_N157_I0.5740.93
13_E16_G0.5740.93
259_G262_T0.5740.93
244_L334_T0.5730.93
238_E452_R0.5730.93
96_V146_L0.5720.93
426_Y505_Y0.5710.92
219_I251_N0.5710.92
348_G393_T0.5710.92
157_I174_L0.5700.92
276_F280_S0.5700.92
234_E239_L0.5700.92
103_N197_Y0.5690.92
425_K459_K0.5690.92
4_I199_N0.5690.92
428_G501_G0.5690.92
286_L335_F0.5680.92
52_I395_T0.5680.92
249_D302_K0.5680.92
188_I200_V0.5650.92
101_Y109_Y0.5650.92
16_G49_A0.5650.92
192_F201_L0.5650.92
24_M168_E0.5640.92
73_L145_R0.5630.92
161_K167_P0.5620.92
219_I250_E0.5620.92
344_V348_G0.5590.92
32_M50_E0.5590.92
329_R450_R0.5580.92
46_I200_V0.5580.92
440_E491_K0.5560.91
270_A322_G0.5550.91
263_Q316_P0.5550.91
35_S56_L0.5550.91
368_Y407_Y0.5540.91
66_T81_L0.5540.91
283_I287_I0.5530.91
235_I449_E0.5530.91
133_T163_N0.5520.91
504_G508_P0.5520.91
159_I162_H0.5490.91
383_D507_T0.5490.91
451_F467_A0.5480.91
79_I148_R0.5480.91
242_I311_V0.5470.91
242_I257_F0.5470.91
367_A398_T0.5470.91
258_A262_T0.5460.91
223_G248_V0.5450.91
110_V181_N0.5450.91
387_A414_Y0.5450.91
245_K258_A0.5450.91
210_Y292_P0.5440.91
463_N466_P0.5430.90
104_G198_D0.5420.90
67_L73_L0.5400.90
85_Y318_A0.5390.90
149_K153_N0.5370.90
156_I160_I0.5370.90
222_W287_I0.5370.90
11_I188_I0.5370.90
90_H93_D0.5370.90
310_I326_T0.5360.90
326_T330_I0.5360.90
223_G227_G0.5360.90
131_A267_P0.5350.90
413_I496_I0.5350.90
98_A101_Y0.5340.90
13_E50_E0.5340.90
29_R406_Y0.5330.90
488_I495_I0.5330.90
153_N158_N0.5320.90
335_F344_V0.5310.89
157_I161_K0.5310.89
133_T318_A0.5300.89
15_M110_V0.5300.89
502_G506_Y0.5300.89
423_V507_T0.5300.89
385_V388_V0.5280.89
158_N167_P0.5280.89
481_M487_T0.5270.89
480_E498_E0.5260.89
386_S416_I0.5260.89
185_I188_I0.5250.89
257_F334_T0.5250.89
122_P133_T0.5250.89
26_P406_Y0.5250.89
63_V67_L0.5240.89
81_L143_P0.5230.89
54_V392_M0.5230.89
102_Y198_D0.5230.89
451_F469_V0.5210.89
212_K251_N0.5210.89
450_R454_A0.5210.89
409_I438_V0.5190.88
77_D150_G0.5180.88
160_I170_S0.5180.88
228_E340_H0.5170.88
282_V335_F0.5160.88
420_S431_G0.5160.88
136_E163_N0.5150.88
168_E171_I0.5140.88
24_M175_N0.5140.88
27_N369_Y0.5130.88
103_N198_D0.5130.88
280_S301_I0.5130.88
412_T415_R0.5130.88
281_F285_S0.5130.88
144_V158_N0.5120.88
103_N192_F0.5120.88
7_A10_F0.5120.88
151_E154_N0.5110.88
276_F295_E0.5110.88
488_I491_K0.5100.88
357_M361_Y0.5100.88
66_T73_L0.5100.88
139_F164_F0.5090.87
58_S62_G0.5090.87
72_E145_R0.5090.87
22_S176_A0.5070.87
378_A426_Y0.5070.87
127_L368_Y0.5060.87
213_K220_S0.5060.87
271_V274_V0.5050.87
220_S224_N0.5050.87
333_V337_A0.5040.87
253_V301_I0.5040.87
240_K329_R0.5040.87
266_G318_A0.5020.87
49_A52_I0.5020.87
145_R155_E0.5020.87
131_A137_E0.5010.87
51_H55_H0.5010.87
128_N267_P0.5000.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1j5kA 1 0.1299 37.6 0.979 Contact Map
2kzxA 1 0.2343 37.1 0.979 Contact Map
3ke6A 2 0.5079 33.6 0.979 Contact Map
3k92A 5 0.4035 29.3 0.98 Contact Map
2yfqA 5 0.3819 28.8 0.98 Contact Map
3o6uA 1 0.2323 26.2 0.98 Contact Map
3aoeE 3 0.3878 25.7 0.981 Contact Map
3by8A 2 0.2264 20.9 0.981 Contact Map
4dzoA 2 0.2323 19.8 0.982 Contact Map
1p0zA 4 0.2224 19.7 0.982 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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