GREMLIN Database
PF09527 - ATP synthase-associated magnesium import membrane protein AtpZ
UniProt: Q74GB0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 81 (66)
Sequences: 12661 (8643)
Seq/√Len: 1063.9
META: 0.87

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
35_Q39_W3.2361.00
31_L35_Q2.7231.00
35_Q38_K2.6301.00
31_L34_R2.6051.00
36_L46_F2.4621.00
60_R64_I2.3971.00
30_V34_R2.1541.00
37_D42_T2.1361.00
21_S61_N2.0671.00
34_R38_K1.8661.00
20_I24_L1.7491.00
45_W49_I1.6611.00
59_F63_Y1.5971.00
42_T46_F1.5771.00
30_V47_F1.5091.00
27_I31_L1.3631.00
32_I50_F1.3511.00
17_S21_S1.3311.00
63_Y67_G1.3121.00
33_G37_D1.2801.00
16_S19_G1.2351.00
40_L46_F1.2061.00
30_V51_L1.1571.00
29_G50_F1.1381.00
55_I59_F1.1251.00
13_G16_S1.1211.00
34_R43_H1.1021.00
53_F57_A1.0991.00
9_I12_L1.0831.00
25_A29_G1.0771.00
44_P47_F1.0711.00
56_A60_R1.0631.00
54_G58_G1.0561.00
61_N64_I1.0391.00
51_L55_I0.9701.00
16_S20_I0.9531.00
25_A61_N0.9411.00
14_L65_I0.9371.00
52_F56_A0.9341.00
48_F52_F0.9321.00
14_L17_S0.9111.00
11_T15_V0.8681.00
43_H47_F0.8571.00
36_L50_F0.8181.00
46_F50_F0.8181.00
17_S20_I0.8101.00
24_L28_I0.8031.00
15_V21_S0.8021.00
11_T14_L0.7881.00
9_I13_G0.7771.00
44_P48_F0.7701.00
36_L40_L0.7551.00
6_R10_Q0.7491.00
7_R10_Q0.7401.00
61_N65_I0.7351.00
22_V58_G0.7331.00
18_M62_I0.7301.00
67_G70_I0.7301.00
62_I66_A0.7121.00
64_I67_G0.7121.00
37_D44_P0.6921.00
57_A61_N0.6891.00
25_A28_I0.6831.00
21_S25_A0.6791.00
23_A27_I0.6771.00
28_I31_L0.6711.00
46_F49_I0.6661.00
32_I36_L0.6581.00
21_S65_I0.6551.00
27_I34_R0.6531.00
19_G55_I0.6471.00
18_M65_I0.6341.00
7_R11_T0.6341.00
25_A57_A0.6331.00
37_D46_F0.6221.00
63_Y66_A0.6151.00
32_I35_Q0.5981.00
44_P49_I0.5941.00
68_R71_K0.5931.00
28_I32_I0.5931.00
29_G58_G0.5901.00
67_G71_K0.5881.00
65_I69_A0.5871.00
29_G54_G0.5861.00
37_D47_F0.5831.00
9_I16_S0.5751.00
42_T45_W0.5521.00
26_I58_G0.5491.00
8_L12_L0.5391.00
25_A58_G0.5281.00
18_M58_G0.5261.00
19_G23_A0.5211.00
57_A60_R0.5141.00
59_F62_I0.5071.00
60_R63_Y0.5051.00
15_V69_A0.5021.00
51_L54_G0.5021.00
22_V62_I0.5001.00
38_K41_G0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4mt1A 3 0.9383 30.7 0.854 Contact Map
4k0jA 3 0.8395 30 0.855 Contact Map
4w6vA 1 0.8148 29.2 0.856 Contact Map
2m67A 1 0.9383 28.6 0.857 Contact Map
4tphA 2 0.716 27.1 0.858 Contact Map
4ikvA 1 0.8148 26.7 0.859 Contact Map
3w9iA 3 0.9012 23.5 0.863 Contact Map
4pypA 1 0.8025 23.2 0.863 Contact Map
1pw4A 1 0.9136 21.4 0.865 Contact Map
2kncA 1 0.6049 20.9 0.866 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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