GREMLIN Database
PF10618 - Tail tube protein, bacteriophage
UniProt: F3Z2T5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 121 (115)
Sequences: 1449 (1180)
Seq/√Len: 110.0
META: 0.557

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
73_I76_A2.9961.00
58_E107_A2.7611.00
35_E49_T2.2411.00
56_E111_R2.2311.00
54_F111_R2.1831.00
75_G92_E2.1431.00
34_R48_E2.1031.00
35_E47_K2.0311.00
38_V52_V1.9261.00
36_A113_E1.9101.00
66_D69_N1.8781.00
22_K107_A1.8471.00
11_Y81_E1.7961.00
33_K49_T1.7821.00
39_G44_H1.7801.00
36_A94_W1.7671.00
17_K69_N1.7401.00
26_T100_S1.7341.00
28_N54_F1.7261.00
41_D44_H1.6571.00
90_L93_A1.5851.00
36_A52_V1.5811.00
56_E109_A1.5701.00
22_K60_T1.5631.00
44_H60_T1.5561.00
58_E109_A1.5491.00
90_L114_G1.4921.00
26_T56_E1.4841.00
66_D119_E1.4751.00
28_N100_S1.4281.00
81_E87_V1.4121.00
6_R20_D1.4091.00
24_S58_E1.3991.00
15_D76_A1.3701.00
25_F57_G1.3471.00
33_K51_Q1.3421.00
43_V94_W1.3281.00
78_V112_F1.3150.99
97_G111_R1.3010.99
26_T102_T1.2880.99
32_P48_E1.2660.99
102_T107_A1.2620.99
27_Y88_F1.2180.99
61_D86_K1.2140.99
33_K98_D1.2130.99
33_K97_G1.1980.99
39_G45_G1.1940.99
13_K18_L1.1790.99
96_A113_E1.1750.99
54_F113_E1.1540.99
53_P90_L1.1390.98
68_E72_T1.1120.98
95_F99_G1.1110.98
28_N51_Q1.1090.98
40_A103_T1.0960.98
90_L117_G1.0930.98
24_S104_E1.0930.98
79_T87_V1.0860.98
25_F80_L1.0590.98
53_P115_M1.0580.98
21_V57_G1.0550.98
13_K81_E1.0060.97
51_Q98_D0.9870.96
36_A96_A0.9750.96
55_I90_L0.9710.96
53_P117_G0.9650.96
27_Y80_L0.9510.95
11_Y18_L0.9460.95
10_L21_V0.9440.95
95_F110_V0.9360.95
13_K79_T0.9320.95
6_R62_R0.9290.95
34_R74_D0.9270.95
34_R46_Y0.9240.95
55_I114_G0.9210.95
6_R60_T0.8860.93
37_I47_K0.8840.93
6_R37_I0.8800.93
46_Y94_W0.8760.93
37_I60_T0.8710.93
73_I112_F0.8710.93
14_I19_Y0.8670.93
10_L78_V0.8670.93
86_K119_E0.8660.93
55_I80_L0.8650.93
91_R118_E0.8610.92
52_V113_E0.8510.92
47_K104_E0.8400.91
38_V43_V0.8350.91
20_D62_R0.8330.91
48_E74_D0.8310.91
29_T117_G0.8290.91
7_A61_D0.8290.91
53_P114_G0.8260.91
24_S102_T0.8180.90
22_K37_I0.8050.90
61_D84_N0.7980.89
12_L57_G0.7880.89
22_K58_E0.7790.88
92_E115_M0.7750.88
5_A83_R0.7740.88
12_L59_I0.7720.88
5_A9_K0.7710.87
61_D101_V0.7620.87
29_T88_F0.7510.86
21_V25_F0.7490.86
5_A48_E0.7240.84
15_D69_N0.7230.84
67_L108_I0.7180.83
14_I73_I0.7160.83
9_K40_A0.7150.83
61_D65_L0.7140.83
102_T105_E0.7090.83
49_T104_E0.6920.81
78_V93_A0.6880.81
71_V99_G0.6840.80
71_V95_F0.6800.80
30_G53_P0.6770.80
58_E102_T0.6730.79
36_A43_V0.6700.79
55_I78_V0.6690.79
61_D108_I0.6630.78
79_T89_V0.6600.78
46_Y74_D0.6560.78
27_Y101_V0.6540.77
45_G60_T0.6470.77
88_F117_G0.6430.76
15_D73_I0.6380.76
10_L80_L0.6380.76
31_Q71_V0.6340.75
30_G117_G0.6250.74
95_F112_F0.6170.73
65_L108_I0.6160.73
48_E94_W0.6140.73
11_Y79_T0.6080.72
7_A106_A0.6050.72
39_G60_T0.6010.71
101_V108_I0.5980.71
82_L88_F0.5970.71
32_P50_Q0.5960.71
40_A49_T0.5930.70
100_S109_A0.5900.70
70_L73_I0.5870.69
73_I95_F0.5840.69
19_Y110_V0.5820.69
54_F100_S0.5810.69
40_A50_Q0.5790.68
18_L79_T0.5760.68
7_A47_K0.5750.68
56_E113_E0.5720.67
19_Y59_I0.5650.67
38_V50_Q0.5630.66
93_A117_G0.5610.66
59_I110_V0.5600.66
56_E75_G0.5530.65
91_R116_S0.5520.65
94_W113_E0.5520.65
34_R94_W0.5480.64
52_V96_A0.5380.63
41_D60_T0.5370.63
57_G112_F0.5370.63
52_V94_W0.5360.63
29_T67_L0.5350.62
7_A37_I0.5330.62
39_G43_V0.5330.62
43_V52_V0.5260.61
27_Y55_I0.5200.60
27_Y90_L0.5200.60
77_T89_V0.5030.58
9_K32_P0.5030.58
88_F119_E0.5020.58
58_E105_E0.5000.57
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4xinA 2 0.876 39.1 0.899 Contact Map
4zjmA 3 0.8678 33.1 0.903 Contact Map
4q1zA 1 0.5124 10.8 0.923 Contact Map
1v7wA 2 0.3223 9.5 0.925 Contact Map
2ypvA 1 0.876 9.1 0.925 Contact Map
4aw7A 1 0.7107 7.8 0.927 Contact Map
3j9qS 11 0.9256 7.8 0.928 Contact Map
3d37A 5 0.7107 7.6 0.928 Contact Map
2xetA 1 0.6364 7.2 0.929 Contact Map
3mzfA 1 0.2893 5.8 0.932 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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