GREMLIN Database
PF09956 - Uncharacterized protein
UniProt: F2J3R1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 108 (106)
Sequences: 1062 (872)
Seq/√Len: 84.6
META:

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
53_D104_R2.9451.00
38_A44_V2.7421.00
62_W103_G2.6451.00
56_K94_V2.6171.00
32_G46_T2.4781.00
18_A40_I2.2891.00
66_A79_T2.2681.00
77_T87_I2.2631.00
67_K86_L2.1751.00
20_A23_D2.1541.00
24_G31_F2.0701.00
12_T45_E2.0301.00
47_A52_F1.8891.00
63_T66_A1.8671.00
57_V76_R1.7771.00
18_A39_A1.7641.00
71_D74_N1.7351.00
13_L46_T1.7061.00
25_L46_T1.6871.00
9_N49_V1.6501.00
96_S99_G1.6391.00
62_W68_V1.6351.00
1_M35_A1.6201.00
1_M52_F1.6101.00
11_I91_V1.5791.00
10_T45_E1.5601.00
68_V90_A1.5381.00
29_S67_K1.5361.00
48_L106_R1.5201.00
12_T43_P1.4640.99
92_E104_R1.4500.99
62_W90_A1.3560.99
35_A47_A1.3190.99
15_A38_A1.3050.99
26_L31_F1.3010.98
95_A99_G1.2030.97
5_V53_D1.1950.97
31_F87_I1.1860.97
82_T85_T1.1820.97
20_A37_A1.1570.97
33_I54_I1.1460.97
16_P40_I1.1290.96
13_L38_A1.1280.96
58_G99_G1.1270.96
95_A100_D1.0870.95
72_D75_K1.0590.95
68_V105_V1.0260.94
24_G70_W0.9960.93
36_G45_E0.9830.92
39_A42_E0.9640.91
15_A40_I0.9600.91
69_Y84_N0.9550.91
96_S100_D0.9530.91
94_V103_G0.9470.91
68_V77_T0.9420.91
53_D102_I0.9390.90
70_W74_N0.9260.90
30_I89_V0.9250.90
13_L44_V0.9250.90
78_T84_N0.9240.90
11_I30_I0.9130.89
58_G96_S0.9060.89
57_V60_Q0.9040.89
15_A19_V0.8990.88
5_V104_R0.8930.88
60_Q103_G0.8800.87
64_V91_V0.8780.87
26_L85_T0.8750.87
13_L19_V0.8740.87
54_I77_T0.8720.87
60_Q78_T0.8560.86
59_S94_V0.8490.85
4_Y7_P0.8460.85
26_L72_D0.8400.85
59_S100_D0.8380.85
27_V44_V0.8360.84
60_Q79_T0.8320.84
19_V44_V0.8290.84
25_L44_V0.8270.84
14_T64_V0.8130.83
24_G87_I0.8080.82
17_Y40_I0.8050.82
23_D34_A0.8030.82
59_S99_G0.7990.82
69_Y80_V0.7950.81
19_V23_D0.7760.80
55_T76_R0.7730.79
69_Y86_L0.7570.78
19_V34_A0.7540.78
49_V106_R0.7520.78
8_G51_V0.7480.77
6_Q51_V0.7480.77
54_I87_I0.7440.77
31_F70_W0.7420.77
15_A44_V0.7400.76
94_V100_D0.7330.76
89_V108_N0.7330.76
59_S96_S0.7330.76
9_N47_A0.7280.75
29_S89_V0.7240.75
19_V25_L0.7160.74
62_W77_T0.7150.74
10_T47_A0.7150.74
16_P44_V0.7020.73
18_A41_G0.6960.72
35_A45_E0.6930.72
18_A37_A0.6880.71
19_V38_A0.6810.70
57_V74_N0.6790.70
66_A93_A0.6700.69
67_K85_T0.6600.68
80_V83_D0.6600.68
71_D76_R0.6580.68
17_Y75_K0.6570.68
3_T21_S0.6550.67
48_L89_V0.6550.67
49_V52_F0.6510.67
17_Y25_L0.6480.67
69_Y78_T0.6470.66
15_A42_E0.6410.66
77_T103_G0.6370.65
86_L89_V0.6330.65
27_V64_V0.6310.64
16_P27_V0.6290.64
26_L33_I0.6110.62
10_T35_A0.6020.61
15_A41_G0.5980.60
19_V40_I0.5960.60
4_Y50_G0.5910.59
67_K89_V0.5910.59
32_G48_L0.5870.59
76_R101_T0.5800.58
38_A46_T0.5800.58
62_W79_T0.5770.58
18_A44_V0.5760.57
29_S85_T0.5700.57
61_A95_A0.5690.57
51_V91_V0.5680.56
30_I48_L0.5660.56
58_G100_D0.5640.56
86_L108_N0.5630.56
83_D108_N0.5590.55
30_I87_I0.5580.55
58_G94_V0.5510.54
80_V84_N0.5510.54
59_S95_A0.5500.54
66_A90_A0.5450.53
73_T83_D0.5350.52
4_Y47_A0.5300.51
73_T76_R0.5230.50
90_A94_V0.5230.50
69_Y88_G0.5200.50
63_T93_A0.5160.50
35_A52_F0.5110.49
61_A103_G0.5110.49
61_A79_T0.5060.48
71_D80_V0.5030.48
69_Y81_A0.5000.47
89_V106_R0.5000.47
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3k3sA 2 0.4907 22.8 0.914 Contact Map
3lazA 2 0.4907 22.7 0.914 Contact Map
4p5nA 2 0.4722 17.6 0.918 Contact Map
2xr4A 2 0.5463 14.4 0.921 Contact Map
4bkfC 1 0.25 12.7 0.924 Contact Map
1hyoA 2 0.3519 10.8 0.926 Contact Map
2chhA 4 0.537 9.1 0.928 Contact Map
4ce8A 4 0.5463 8.8 0.929 Contact Map
4dbfA 2 0.5463 7.5 0.931 Contact Map
4qkuA 2 0.3611 7 0.932 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0051 seconds.