THSA - SULSO - GREMLIN Contacts

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THSA - Thermosome subunit alpha

UniProt:	Q9V2S9	Sequences: MAAPVLLLKEGTSRTTGRDALRNNILAAKTLAEMLRSSLGPKGLDKMLIDSFGDVTITNDGATIVKDMEIQHPAAKLLVEAAKAQDAEVGDGTTSAVVLAGALLEKAESLLDQNIHPTIIIEGYKKAYNKALELLPQLGTRIDIKDLNSSVARDTLRKIAFTTLASKFIAEGAELNKIIDMVIDAIVNVAEPLPNGGYNVSLDLIKIDKKKGGSIEDSVLVKGLVLDKEVVHPGMPRRVTKAKIAVLDAALEVEKPEISAKISITSPEQIKAFLDEESKYLKDMVDKLASIGANVVICQKGIDDIAQHFLAKKGILAVRRVKRSDIEKLEKALGARIISSIKDATPEDLGYAELVEERRVGNDKMVFIEGAKNLKAVNILLRGSNDMALDEAERSINDALHALRNILLEPVILPGGGAIELELAMKLREYARSVGGKEQLAIEAFADALEEIPLILAETAGLEAISSLMDLRARHAKGLSNTGVDVIGGKIVDDVYALNIIEPIRVKSQVLKSATEAATAILKIDDLIAAAPLKSEKKGGEGSKEESGGEGGSTPSLGD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	559 (490)
Sequences:	5434 (2272)
Seq/√Len:	102.6

ECOLI - CH60
BACSU - CH60
HALSA - THSA THSB
SULSO - THSA THSB THSG

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
130_K	133_E	4.892	1.00
139_G	504_I	4.720	1.00
135_L	504_I	4.463	1.00
494_D	497_A	4.171	1.00
153_R	184_D	4.157	1.00
134_L	137_Q	4.131	1.00
485_D	488_G	4.011	1.00
296_V	346_P	3.714	1.00
434_V	442_I	3.675	1.00
157_R	180_D	3.567	1.00
353_E	370_G	3.545	1.00
180_D	184_D	3.435	1.00
481_N	494_D	3.273	1.00
106_K	447_D	3.198	1.00
453_P	471_L	3.116	1.00
126_K	438_E	3.085	1.00
420_E	507_K	3.059	1.00
153_R	187_V	2.961	1.00
59_N	64_I	2.956	1.00
462_L	484_V	2.889	1.00
128_Y	515_T	2.875	1.00
484_V	489_G	2.842	1.00
286_D	290_S	2.744	1.00
128_Y	511_L	2.730	1.00
103_L	124_Y	2.682	1.00
467_S	491_I	2.680	1.00
124_Y	515_T	2.669	1.00
450_E	472_R	2.567	1.00
218_S	381_L	2.567	1.00
427_L	442_I	2.528	1.00
470_D	473_A	2.401	1.00
125_K	519_T	2.383	1.00
474_R	482_T	2.368	1.00
135_L	419_I	2.338	1.00
70_I	73_P	2.334	1.00
428_R	446_A	2.314	1.00
130_K	430_Y	2.285	1.00
302_I	317_A	2.273	1.00
134_L	426_K	2.272	1.00
133_E	137_Q	2.255	1.00
416_G	495_V	2.160	1.00
29_K	33_E	2.155	1.00
103_L	445_F	2.147	1.00
485_D	498_L	2.129	1.00
279_K	283_D	2.125	1.00
76_K	79_V	2.105	1.00
136_P	508_S	2.097	1.00
129_N	133_E	2.073	1.00
29_K	101_G	2.069	1.00
445_F	515_T	2.067	1.00
36_R	101_G	2.031	1.00
308_H	311_A	2.015	1.00
104_L	521_I	1.969	1.00
26_L	30_T	1.963	1.00
25_I	29_K	1.963	1.00
430_Y	433_S	1.958	1.00
140_T	496_Y	1.951	1.00
239_V	242_A	1.933	1.00
238_R	354_L	1.928	1.00
131_A	423_L	1.897	1.00
95_S	510_V	1.880	1.00
462_L	489_G	1.875	1.00
352_A	368_I	1.874	1.00
161_F	176_N	1.872	1.00
474_R	479_L	1.858	1.00
188_N	222_K	1.857	1.00
130_K	426_K	1.836	1.00
119_I	438_E	1.829	1.00
457_A	462_L	1.822	1.00
430_Y	442_I	1.818	1.00
153_R	180_D	1.810	1.00
182_V	396_I	1.805	1.00
426_K	429_E	1.801	1.00
155_T	158_K	1.792	1.00
124_Y	445_F	1.786	1.00
181_M	379_I	1.773	1.00
32_A	101_G	1.771	1.00
18_R	22_R	1.767	1.00
56_T	394_R	1.765	1.00
241_K	267_P	1.751	1.00
102_A	105_E	1.729	1.00
329_L	368_I	1.721	1.00
394_R	397_N	1.719	1.00
412_I	501_I	1.716	1.00
245_A	344_A	1.710	1.00
181_M	218_S	1.707	1.00
334_G	337_I	1.701	1.00
421_L	453_P	1.698	1.00
134_L	138_L	1.694	1.00
23_N	26_L	1.685	1.00
237_R	296_V	1.679	1.00
186_I	407_L	1.674	1.00
320_R	337_I	1.673	1.00
14_R	526_D	1.650	1.00
86_D	394_R	1.648	1.00
110_L	440_L	1.647	1.00
282_K	286_D	1.643	1.00
132_L	136_P	1.640	1.00
107_A	124_Y	1.620	1.00
121_I	125_K	1.605	1.00
470_D	474_R	1.596	1.00
246_V	319_R	1.584	1.00
450_E	454_L	1.582	1.00
495_V	500_I	1.579	1.00
59_N	394_R	1.564	1.00
239_V	270_I	1.541	1.00
422_E	480_S	1.532	1.00
209_K	390_D	1.529	1.00
470_D	490_K	1.528	1.00
176_N	180_D	1.513	1.00
419_I	423_L	1.505	1.00
122_E	438_E	1.502	1.00
457_A	464_A	1.500	1.00
131_A	449_L	1.497	1.00
106_K	109_S	1.490	1.00
110_L	115_I	1.486	1.00
29_K	105_E	1.480	1.00
451_E	455_I	1.474	1.00
54_D	387_M	1.468	1.00
427_L	446_A	1.450	1.00
186_I	205_I	1.442	1.00
297_I	368_I	1.441	1.00
127_A	445_F	1.439	1.00
130_K	442_I	1.430	1.00
130_K	134_L	1.429	1.00
133_E	136_P	1.427	1.00
132_L	512_K	1.426	1.00
288_L	291_I	1.414	1.00
449_L	511_L	1.411	1.00
418_A	422_E	1.407	1.00
33_E	101_G	1.397	1.00
479_L	494_D	1.390	1.00
246_V	335_A	1.388	1.00
424_A	472_R	1.386	1.00
425_M	429_E	1.367	0.99
26_L	71_Q	1.365	0.99
421_L	472_R	1.353	0.99
272_A	313_K	1.342	0.99
383_G	389_L	1.340	0.99
379_I	396_I	1.329	0.99
322_K	333_L	1.312	0.99
219_V	380_L	1.311	0.99
138_L	141_R	1.306	0.99
217_D	380_L	1.298	0.99
430_Y	434_V	1.293	0.99
261_K	334_G	1.290	0.99
408_L	505_R	1.287	0.99
86_D	401_H	1.286	0.99
140_T	155_T	1.284	0.99
209_K	393_E	1.281	0.99
287_K	290_S	1.267	0.99
131_A	427_L	1.264	0.99
28_A	521_I	1.250	0.99
239_V	294_N	1.248	0.99
289_A	315_I	1.247	0.99
25_I	104_L	1.241	0.99
318_V	366_V	1.230	0.99
59_N	165_A	1.227	0.99
482_T	491_I	1.226	0.99
102_A	451_E	1.217	0.99
439_Q	443_E	1.216	0.99
453_P	457_A	1.208	0.99
429_E	432_R	1.205	0.99
154_D	157_R	1.203	0.99
126_K	130_K	1.200	0.99
479_L	482_T	1.197	0.99
409_E	505_R	1.197	0.99
127_A	442_I	1.197	0.99
261_K	264_I	1.195	0.99
443_E	447_D	1.189	0.99
469_M	473_A	1.185	0.99
414_P	418_A	1.185	0.99
381_L	389_L	1.184	0.99
58_T	391_E	1.184	0.99
355_V	358_R	1.183	0.99
352_A	358_R	1.181	0.98
381_L	392_A	1.180	0.98
86_D	397_N	1.179	0.98
435_G	442_I	1.165	0.98
115_I	440_L	1.162	0.98
105_E	451_E	1.146	0.98
73_P	527_L	1.139	0.98
159_I	412_I	1.138	0.98
414_P	496_Y	1.125	0.98
13_S	529_A	1.124	0.98
252_E	277_E	1.115	0.98
508_S	512_K	1.113	0.98
485_D	500_I	1.102	0.98
143_D	155_T	1.100	0.98
135_L	508_S	1.094	0.98
422_E	481_N	1.093	0.98
28_A	78_L	1.087	0.97
246_V	321_V	1.077	0.97
226_L	298_C	1.074	0.97
329_L	332_A	1.074	0.97
81_A	96_A	1.068	0.97
243_K	292_G	1.065	0.97
15_T	70_I	1.057	0.97
394_R	401_H	1.056	0.97
297_I	321_V	1.051	0.97
496_Y	501_I	1.048	0.97
443_E	446_A	1.047	0.97
242_A	295_V	1.047	0.97
359_R	362_N	1.046	0.97
39_L	98_V	1.040	0.97
436_G	439_Q	1.035	0.97
423_L	449_L	1.033	0.96
246_V	313_K	1.030	0.96
64_I	394_R	1.029	0.96
357_E	364_K	1.029	0.96
61_G	94_T	1.027	0.96
60_D	63_T	1.025	0.96
349_L	365_M	1.025	0.96
467_S	484_V	1.016	0.96
246_V	330_E	1.016	0.96
462_L	467_S	1.014	0.96
243_K	340_S	1.007	0.96
413_L	504_I	1.000	0.96
301_G	304_D	1.000	0.96
36_R	455_I	1.000	0.96
138_L	480_S	1.000	0.96
266_S	269_Q	0.997	0.96
15_T	23_N	0.994	0.96
73_P	529_A	0.993	0.96
481_N	496_Y	0.992	0.96
126_K	434_V	0.986	0.95
137_Q	426_K	0.986	0.95
60_D	398_D	0.982	0.95
157_R	160_A	0.982	0.95
50_D	67_D	0.981	0.95
469_M	472_R	0.979	0.95
28_A	104_L	0.977	0.95
33_E	36_R	0.977	0.95
94_T	398_D	0.975	0.95
267_P	340_S	0.975	0.95
184_D	222_K	0.968	0.95
503_P	506_V	0.968	0.95
424_A	450_E	0.965	0.95
391_E	394_R	0.964	0.95
275_D	279_K	0.963	0.95
269_Q	272_A	0.958	0.95
530_A	533_L	0.954	0.95
272_A	275_D	0.952	0.94
310_L	317_A	0.950	0.94
135_L	423_L	0.941	0.94
184_D	188_N	0.941	0.94
431_A	439_Q	0.941	0.94
39_L	95_S	0.935	0.94
25_I	108_E	0.933	0.94
288_L	294_N	0.931	0.94
32_A	36_R	0.929	0.94
288_L	293_A	0.928	0.94
251_L	288_L	0.927	0.94
103_L	521_I	0.924	0.94
13_S	531_A	0.923	0.94
456_L	486_V	0.923	0.94
93_T	398_D	0.923	0.94
138_L	423_L	0.921	0.93
82_A	97_V	0.920	0.93
341_I	344_A	0.919	0.93
283_D	287_K	0.917	0.93
215_I	392_A	0.914	0.93
287_K	342_K	0.914	0.93
360_V	363_D	0.912	0.93
462_L	486_V	0.908	0.93
37_S	46_K	0.906	0.93
157_R	161_F	0.906	0.93
396_I	400_L	0.905	0.93
414_P	481_N	0.905	0.93
159_I	402_A	0.905	0.93
144_I	155_T	0.904	0.93
421_L	450_E	0.904	0.93
70_I	529_A	0.904	0.93
271_K	275_D	0.904	0.93
15_T	19_D	0.900	0.93
406_I	410_P	0.899	0.93
132_L	508_S	0.899	0.93
535_S	538_K	0.899	0.93
177_K	216_E	0.895	0.92
425_M	428_R	0.894	0.92
451_E	454_L	0.892	0.92
435_G	438_E	0.890	0.92
11_G	531_A	0.886	0.92
58_T	64_I	0.884	0.92
432_R	443_E	0.884	0.92
437_K	440_L	0.884	0.92
123_G	441_A	0.884	0.92
22_R	26_L	0.883	0.92
134_L	422_E	0.882	0.92
422_E	482_T	0.881	0.92
160_A	403_L	0.878	0.92
128_Y	445_F	0.874	0.92
106_K	448_A	0.874	0.92
156_L	187_V	0.873	0.91
328_K	337_I	0.866	0.91
397_N	401_H	0.865	0.91
521_I	527_L	0.865	0.91
248_D	333_L	0.862	0.91
182_V	379_I	0.860	0.91
48_L	528_I	0.860	0.91
240_T	354_L	0.860	0.91
269_Q	273_F	0.860	0.91
235_M	301_G	0.859	0.91
153_R	157_R	0.856	0.91
156_L	160_A	0.856	0.91
134_L	423_L	0.855	0.91
36_R	458_E	0.855	0.91
400_L	404_R	0.855	0.91
423_L	426_K	0.854	0.91
115_I	437_K	0.850	0.90
25_I	105_E	0.849	0.90
154_D	158_K	0.848	0.90
532_P	536_E	0.848	0.90
419_I	504_I	0.847	0.90
490_K	498_L	0.844	0.90
349_L	355_V	0.843	0.90
504_I	508_S	0.843	0.90
458_E	464_A	0.839	0.90
434_V	438_E	0.838	0.90
123_G	127_A	0.837	0.90
125_K	129_N	0.836	0.90
157_R	176_N	0.836	0.90
70_I	527_L	0.835	0.90
13_S	530_A	0.835	0.90
354_L	369_E	0.834	0.90
78_L	81_A	0.832	0.89
391_E	395_S	0.831	0.89
531_A	535_S	0.829	0.89
130_K	137_Q	0.824	0.89
422_E	471_L	0.822	0.89
289_A	313_K	0.822	0.89
136_P	504_I	0.821	0.89
144_I	154_D	0.821	0.89
246_V	272_A	0.819	0.89
283_D	286_D	0.819	0.89
424_A	449_L	0.817	0.89
33_E	37_S	0.812	0.88
221_V	225_V	0.808	0.88
422_E	425_M	0.805	0.88
421_L	424_A	0.805	0.88
138_L	419_I	0.804	0.88
509_Q	512_K	0.803	0.88
249_A	324_S	0.800	0.87
136_P	139_G	0.797	0.87
119_I	487_I	0.796	0.87
453_P	468_L	0.795	0.87
27_A	74_A	0.795	0.87
444_A	447_D	0.793	0.87
58_T	394_R	0.793	0.87
45_D	59_N	0.792	0.87
328_K	333_L	0.791	0.87
427_L	430_Y	0.790	0.87
186_I	400_L	0.790	0.87
158_K	499_N	0.789	0.87
445_F	449_L	0.789	0.87
323_R	327_E	0.788	0.87
66_K	83_K	0.788	0.87
471_L	491_I	0.785	0.86
457_A	484_V	0.785	0.86
134_L	427_L	0.783	0.86
105_E	512_K	0.779	0.86
335_A	350_G	0.778	0.86
242_A	294_N	0.777	0.86
268_E	272_A	0.777	0.86
244_I	352_A	0.774	0.86
431_A	446_A	0.772	0.86
39_L	452_I	0.771	0.85
244_I	341_I	0.770	0.85
31_L	78_L	0.769	0.85
428_R	443_E	0.768	0.85
185_A	218_S	0.768	0.85
485_D	495_V	0.767	0.85
296_V	310_L	0.765	0.85
358_R	369_E	0.765	0.85
242_A	341_I	0.764	0.85
328_K	332_A	0.763	0.85
50_D	54_D	0.756	0.84
40_G	43_G	0.752	0.84
241_K	340_S	0.751	0.84
95_S	452_I	0.751	0.84
49_I	70_I	0.751	0.84
447_D	450_E	0.749	0.84
76_K	404_R	0.747	0.84
534_K	538_K	0.746	0.84
210_K	389_L	0.746	0.84
128_Y	132_L	0.745	0.83
531_A	536_E	0.745	0.83
82_A	96_A	0.742	0.83
409_E	508_S	0.741	0.83
131_A	426_K	0.741	0.83
111_L	120_I	0.741	0.83
285_V	313_K	0.740	0.83
533_L	536_E	0.740	0.83
159_I	406_I	0.736	0.83
50_D	56_T	0.736	0.83
230_V	316_L	0.734	0.83
27_A	72_H	0.732	0.82
531_A	537_K	0.731	0.82
534_K	537_K	0.727	0.82
247_L	251_L	0.726	0.82
185_A	220_L	0.723	0.82
185_A	205_I	0.722	0.82
124_Y	127_A	0.721	0.81
100_A	514_A	0.720	0.81
61_G	398_D	0.718	0.81
53_G	315_I	0.717	0.81
51_S	533_L	0.717	0.81
65_V	97_V	0.716	0.81
138_L	414_P	0.715	0.81
305_I	309_F	0.714	0.81
251_L	306_A	0.713	0.81
119_I	122_E	0.713	0.81
138_L	426_K	0.712	0.81
320_R	328_K	0.711	0.81
431_A	443_E	0.711	0.81
270_I	346_P	0.710	0.80
244_I	368_I	0.708	0.80
484_V	490_K	0.705	0.80
99_L	514_A	0.704	0.80
126_K	430_Y	0.696	0.79
293_A	349_L	0.693	0.79
186_I	403_L	0.693	0.79
210_K	363_D	0.691	0.79
24_N	527_L	0.690	0.79
242_A	355_V	0.690	0.79
506_V	510_V	0.689	0.78
248_D	323_R	0.689	0.78
161_F	179_I	0.687	0.78
243_K	351_Y	0.686	0.78
428_R	450_E	0.684	0.78
265_T	269_Q	0.683	0.78
18_R	246_V	0.679	0.77
457_A	467_S	0.678	0.77
160_A	183_I	0.677	0.77
126_K	442_I	0.676	0.77
310_L	315_I	0.676	0.77
119_I	435_G	0.676	0.77
436_G	440_L	0.676	0.77
285_V	309_F	0.676	0.77
230_V	235_M	0.675	0.77
249_A	319_R	0.673	0.77
85_Q	513_S	0.672	0.77
58_T	165_A	0.671	0.77
63_T	394_R	0.671	0.77
101_G	105_E	0.670	0.77
243_K	267_P	0.670	0.77
222_K	370_G	0.669	0.76
439_Q	442_I	0.669	0.76
239_V	295_V	0.668	0.76
413_L	419_I	0.668	0.76
24_N	104_L	0.666	0.76
467_S	486_V	0.665	0.76
471_L	474_R	0.665	0.76
301_G	309_F	0.665	0.76
182_V	399_A	0.665	0.76
421_L	468_L	0.664	0.76
470_D	491_I	0.664	0.76
414_P	495_V	0.663	0.76
254_E	283_D	0.663	0.76
338_I	344_A	0.663	0.76
281_L	305_I	0.662	0.76
61_G	90_G	0.662	0.76
502_E	507_K	0.661	0.76
182_V	403_L	0.661	0.76
483_G	495_V	0.661	0.76
450_E	463_E	0.659	0.75
248_D	325_D	0.658	0.75
466_S	470_D	0.658	0.75
428_R	447_D	0.656	0.75
58_T	79_V	0.656	0.75
240_T	343_D	0.656	0.75
86_D	398_D	0.653	0.75
160_A	357_E	0.650	0.74
237_R	346_P	0.649	0.74
19_D	22_R	0.649	0.74
156_L	403_L	0.647	0.74
166_S	507_K	0.647	0.74
415_G	500_I	0.644	0.74
303_D	306_A	0.642	0.73
162_T	166_S	0.641	0.73
231_V	276_E	0.640	0.73
422_E	426_K	0.640	0.73
165_A	394_R	0.640	0.73
111_L	487_I	0.639	0.73
273_F	276_E	0.638	0.73
191_E	375_K	0.638	0.73
214_S	217_D	0.637	0.73
238_R	343_D	0.637	0.73
25_I	115_I	0.637	0.73
510_V	514_A	0.636	0.73
509_Q	513_S	0.635	0.73
236_P	311_A	0.634	0.72
211_K	216_E	0.633	0.72
77_L	517_A	0.633	0.72
230_V	357_E	0.632	0.72
425_M	472_R	0.631	0.72
67_D	235_M	0.630	0.72
239_V	296_V	0.630	0.72
205_I	304_D	0.628	0.72
261_K	265_T	0.628	0.72
110_L	444_A	0.627	0.72
209_K	389_L	0.626	0.72
109_S	113_Q	0.626	0.72
188_N	377_V	0.625	0.71
389_L	392_A	0.625	0.71
474_R	480_S	0.625	0.71
207_I	381_L	0.624	0.71
159_I	410_P	0.622	0.71
166_S	176_N	0.622	0.71
238_R	356_E	0.622	0.71
157_R	183_I	0.621	0.71
36_R	451_E	0.620	0.71
165_A	391_E	0.618	0.71
124_Y	441_A	0.617	0.70
136_P	409_E	0.617	0.70
330_E	337_I	0.617	0.70
413_L	501_I	0.617	0.70
245_A	349_L	0.616	0.70
274_L	306_A	0.616	0.70
166_S	395_S	0.615	0.70
356_E	360_V	0.614	0.70
185_A	189_V	0.614	0.70
494_D	498_L	0.612	0.70
466_S	469_M	0.611	0.70
211_K	386_D	0.610	0.70
61_G	93_T	0.609	0.69
141_R	449_L	0.609	0.69
457_A	468_L	0.609	0.69
88_E	509_Q	0.607	0.69
347_E	380_L	0.606	0.69
267_P	270_I	0.606	0.69
424_A	446_A	0.604	0.69
124_Y	128_Y	0.604	0.69
333_L	337_I	0.603	0.69
70_I	463_E	0.603	0.69
429_E	433_S	0.602	0.69
21_L	525_D	0.601	0.68
82_A	100_A	0.600	0.68
470_D	482_T	0.598	0.68
241_K	351_Y	0.597	0.68
130_K	423_L	0.596	0.68
320_R	333_L	0.595	0.68
262_I	273_F	0.594	0.68
245_A	291_I	0.594	0.68
184_D	187_V	0.594	0.68
140_T	481_N	0.593	0.67
431_A	442_I	0.593	0.67
160_A	179_I	0.593	0.67
107_A	123_G	0.593	0.67
118_T	121_I	0.593	0.67
29_K	108_E	0.593	0.67
263_S	266_S	0.590	0.67
128_Y	512_K	0.589	0.67
47_M	521_I	0.589	0.67
212_G	382_R	0.589	0.67
120_I	445_F	0.588	0.67
323_R	326_I	0.588	0.67
242_A	344_A	0.588	0.67
56_T	67_D	0.588	0.67
66_K	249_A	0.587	0.67
245_A	288_L	0.587	0.67
474_R	491_I	0.587	0.67
322_K	328_K	0.586	0.67
447_D	451_E	0.584	0.66
322_K	337_I	0.584	0.66
479_L	496_Y	0.584	0.66
229_E	232_H	0.584	0.66
305_I	363_D	0.581	0.66
323_R	328_K	0.581	0.66
29_K	32_A	0.580	0.66
253_V	256_P	0.580	0.66
116_H	523_K	0.579	0.66
450_E	489_G	0.578	0.65
262_I	269_Q	0.578	0.65
35_L	94_T	0.577	0.65
356_E	369_E	0.577	0.65
280_Y	284_M	0.576	0.65
104_L	442_I	0.575	0.65
533_L	537_K	0.575	0.65
354_L	375_K	0.574	0.65
460_A	486_V	0.573	0.65
13_S	527_L	0.573	0.65
532_P	535_S	0.572	0.65
224_L	316_L	0.572	0.65
245_A	293_A	0.570	0.64
39_L	94_T	0.570	0.64
72_H	76_K	0.569	0.64
131_A	134_L	0.569	0.64
440_L	446_A	0.568	0.64
402_A	406_I	0.568	0.64
485_D	490_K	0.568	0.64
166_S	513_S	0.568	0.64
270_I	298_C	0.568	0.64
322_K	327_E	0.568	0.64
322_K	334_G	0.567	0.64
115_I	436_G	0.567	0.64
383_G	522_L	0.567	0.64
137_Q	140_T	0.566	0.64
158_K	161_F	0.566	0.64
63_T	398_D	0.565	0.64
431_A	434_V	0.565	0.64
48_L	484_V	0.565	0.64
263_S	292_G	0.564	0.64
230_V	366_V	0.563	0.63
453_P	469_M	0.563	0.63
246_V	329_L	0.562	0.63
280_Y	283_D	0.561	0.63
528_I	531_A	0.561	0.63
160_A	163_T	0.559	0.63
131_A	446_A	0.559	0.63
305_I	357_E	0.558	0.63
24_N	73_P	0.557	0.63
262_I	284_M	0.556	0.62
455_I	458_E	0.556	0.62
92_G	506_V	0.556	0.62
386_D	390_D	0.556	0.62
76_K	80_E	0.555	0.62
13_S	22_R	0.555	0.62
153_R	528_I	0.555	0.62
282_K	290_S	0.554	0.62
39_L	42_K	0.553	0.62
24_N	521_I	0.553	0.62
418_A	471_L	0.550	0.62
447_D	465_I	0.549	0.62
189_V	220_L	0.548	0.61
34_M	62_A	0.548	0.61
293_A	296_V	0.547	0.61
205_I	400_L	0.547	0.61
240_T	370_G	0.547	0.61
127_A	154_D	0.546	0.61
394_R	423_L	0.544	0.61
102_A	455_I	0.544	0.61
90_G	93_T	0.544	0.61
32_A	35_L	0.543	0.61
110_L	522_L	0.543	0.61
24_N	47_M	0.543	0.61
414_P	482_T	0.542	0.61
78_L	521_I	0.542	0.61
319_R	322_K	0.542	0.61
270_I	296_V	0.541	0.60
59_N	167_K	0.541	0.60
131_A	511_L	0.540	0.60
320_R	325_D	0.540	0.60
450_E	465_I	0.540	0.60
300_K	303_D	0.539	0.60
177_K	184_D	0.539	0.60
103_L	128_Y	0.539	0.60
311_A	323_R	0.539	0.60
104_L	248_D	0.538	0.60
531_A	534_K	0.538	0.60
282_K	313_K	0.538	0.60
119_I	437_K	0.537	0.60
260_A	263_S	0.537	0.60
248_D	326_I	0.536	0.60
329_L	333_L	0.536	0.60
95_S	99_L	0.536	0.60
59_N	521_I	0.535	0.60
311_A	325_D	0.535	0.60
326_I	329_L	0.534	0.59
308_H	312_K	0.534	0.59
166_S	216_E	0.533	0.59
219_V	369_E	0.533	0.59
36_R	80_E	0.532	0.59
291_I	296_V	0.532	0.59
315_I	347_E	0.532	0.59
265_T	335_A	0.531	0.59
141_R	144_I	0.531	0.59
86_D	93_T	0.531	0.59
104_L	520_A	0.530	0.59
107_A	445_F	0.530	0.59
121_I	520_A	0.530	0.59
58_T	94_T	0.529	0.59
47_M	73_P	0.528	0.59
425_M	482_T	0.528	0.59
181_M	381_L	0.528	0.59
15_T	531_A	0.528	0.59
236_P	314_G	0.528	0.59
57_I	532_P	0.527	0.58
16_T	214_S	0.525	0.58
243_K	265_T	0.525	0.58
205_I	396_I	0.525	0.58
520_A	524_I	0.525	0.58
248_D	328_K	0.525	0.58
381_L	396_I	0.524	0.58
136_P	536_E	0.524	0.58
424_A	451_E	0.524	0.58
243_K	262_I	0.523	0.58
334_G	350_G	0.522	0.58
88_E	408_L	0.521	0.58
122_E	519_T	0.521	0.58
45_D	523_K	0.521	0.58
232_H	319_R	0.520	0.57
275_D	299_Q	0.520	0.57
162_T	502_E	0.520	0.57
111_L	117_P	0.519	0.57
142_I	177_K	0.518	0.57
154_D	497_A	0.518	0.57
244_I	333_L	0.516	0.57
82_A	86_D	0.516	0.57
121_I	519_T	0.516	0.57
400_L	531_A	0.515	0.57
62_A	66_K	0.515	0.57
287_K	341_I	0.515	0.57
317_A	375_K	0.514	0.57
153_R	160_A	0.514	0.57
34_M	38_S	0.513	0.56
15_T	527_L	0.513	0.56
164_L	178_I	0.513	0.56
294_N	349_L	0.512	0.56
90_G	398_D	0.512	0.56
428_R	472_R	0.511	0.56
233_P	268_E	0.510	0.56
251_L	257_E	0.510	0.56
18_R	21_L	0.509	0.56
354_L	370_G	0.508	0.56
305_I	308_H	0.508	0.56
399_A	407_L	0.507	0.56
285_V	306_A	0.507	0.56
78_L	100_A	0.507	0.56
125_K	516_E	0.506	0.55
279_K	282_K	0.506	0.55
123_G	499_N	0.506	0.55
95_S	506_V	0.505	0.55
300_K	322_K	0.505	0.55
22_R	25_I	0.505	0.55
24_N	407_L	0.505	0.55
129_N	429_E	0.505	0.55
85_Q	96_A	0.504	0.55
279_K	375_K	0.503	0.55
53_G	159_I	0.503	0.55
117_P	310_L	0.503	0.55
396_I	402_A	0.503	0.55
13_S	18_R	0.501	0.55
62_A	162_T	0.500	0.55
419_I	502_E	0.500	0.55

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3j1bA	4	0.9231	100	0.05	Contact Map
1q3qA	4	0.9267	100	0.068	Contact Map
3ruvA	6	0.9213	100	0.069	Contact Map
1a6dA	2	0.8998	100	0.076	Contact Map
1a6dB	2	0.898	100	0.077	Contact Map
3ko1A	5	0.9016	100	0.079	Contact Map
3p9dG	1	0.9052	100	0.083	Contact Map
3p9dA	1	0.9428	100	0.096	Contact Map
3p9dH	1	0.9016	100	0.104	Contact Map
3p9dD	2	0.9177	100	0.104	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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