MCM - SULSO - GREMLIN Contacts

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MCM - Minichromosome maintenance protein MCM

UniProt:	Q9UXG1	Sequences: MEIPSKQIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDMESGKIDIDTIMTGKPKSAREKMMKIIEIIDSLAVSSECAKVKDILKEAQQVGIEKSNIEKLLTDMRKSGIIYEAKPECYKKV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	686 (634)
Sequences:	2205 (1338)
Seq/√Len:	53.1

HALSA - Q9HNA5
SULSO - MCM

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
215_I	259_V	8.301	1.00
569_S	581_V	7.050	1.00
295_I	314_A	5.899	1.00
288_D	294_R	5.346	1.00
48_E	102_G	4.908	1.00
285_L	291_I	4.897	1.00
576_A	585_D	4.606	1.00
278_D	515_K	4.346	1.00
318_F	575_M	4.264	1.00
195_A	217_L	4.206	1.00
29_K	51_D	4.178	1.00
316_A	444_I	3.842	1.00
588_R	591_N	3.762	1.00
397_D	440_R	3.529	1.00
14_F	17_F	3.426	1.00
313_L	353_I	3.302	1.00
535_L	587_E	3.290	1.00
509_D	512_T	3.274	1.00
14_F	18_L	3.187	1.00
285_L	508_I	3.179	1.00
531_E	583_R	3.165	1.00
309_L	480_L	3.139	1.00
153_F	172_P	3.134	1.00
529_T	580_E	3.116	1.00
578_K	585_D	3.110	1.00
285_L	512_T	3.068	1.00
529_T	532_A	3.040	1.00
217_L	262_I	2.959	1.00
454_Y	463_N	2.939	1.00
215_I	233_V	2.934	1.00
313_L	349_M	2.865	1.00
281_K	284_D	2.802	1.00
52_V	63_I	2.729	1.00
125_G	197_I	2.676	1.00
15_I	80_D	2.616	1.00
127_L	195_A	2.482	1.00
344_T	480_L	2.425	1.00
649_L	662_I	2.417	1.00
16_E	20_T	2.412	1.00
572_Y	588_R	2.412	1.00
140_A	182_L	2.324	1.00
97_H	219_D	2.317	1.00
275_S	278_D	2.304	1.00
14_F	20_T	2.303	1.00
144_H	149_C	2.295	1.00
110_R	205_P	2.282	1.00
530_S	534_N	2.241	1.00
149_C	171_C	2.236	1.00
37_L	45_L	2.233	1.00
476_L	568_I	2.232	1.00
127_L	231_V	2.197	1.00
143_K	183_I	2.193	1.00
65_N	119_K	2.189	1.00
18_L	21_F	2.187	1.00
629_I	633_I	2.136	1.00
281_K	512_T	2.136	1.00
393_L	443_V	2.113	1.00
308_E	591_N	2.090	1.00
30_Y	37_L	2.089	1.00
455_I	458_R	2.087	1.00
137_I	140_A	2.086	1.00
525_T	574_K	2.050	1.00
420_A	426_V	2.043	1.00
459_P	462_D	2.021	1.00
578_K	582_T	1.972	1.00
508_I	512_T	1.970	1.00
323_K	570_E	1.965	1.00
120_L	260_S	1.938	1.00
279_E	283_K	1.920	1.00
321_V	332_G	1.918	1.00
534_N	538_D	1.903	0.99
360_A	396_A	1.895	0.99
299_I	314_A	1.865	0.99
78_L	96_V	1.858	0.99
643_A	648_I	1.856	0.99
238_D	258_K	1.848	0.99
429_A	434_V	1.839	0.99
46_I	101_V	1.831	0.99
276_E	280_K	1.827	0.99
237_L	255_I	1.824	0.99
296_I	311_E	1.821	0.99
17_F	21_F	1.814	0.99
29_K	33_R	1.809	0.99
149_C	157_E	1.800	0.99
315_L	572_Y	1.793	0.99
519_Y	577_L	1.773	0.99
353_I	400_I	1.772	0.99
34_I	37_L	1.769	0.99
283_K	286_A	1.765	0.99
539_F	590_I	1.754	0.99
312_A	478_F	1.748	0.99
276_E	279_E	1.743	0.99
486_E	489_R	1.735	0.99
393_L	401_A	1.734	0.99
311_E	588_R	1.732	0.99
29_K	35_N	1.729	0.99
99_R	220_D	1.708	0.99
625_K	630_I	1.685	0.99
572_Y	585_D	1.676	0.99
405_E	473_R	1.648	0.98
318_F	520_A	1.647	0.98
348_Q	423_Q	1.638	0.98
617_G	623_R	1.630	0.98
199_E	210_P	1.627	0.98
532_A	586_A	1.624	0.98
583_R	587_E	1.620	0.98
482_D	488_D	1.611	0.98
524_V	579_A	1.597	0.98
285_L	294_R	1.586	0.98
367_G	414_R	1.584	0.98
451_F	455_I	1.579	0.98
363_T	418_H	1.576	0.98
647_D	650_K	1.555	0.98
123_I	197_I	1.553	0.98
630_I	634_D	1.553	0.98
15_I	19_T	1.544	0.98
560_R	567_R	1.538	0.98
621_S	625_K	1.532	0.98
315_L	597_L	1.531	0.97
44_S	220_D	1.516	0.97
284_D	287_K	1.504	0.97
44_S	99_R	1.504	0.97
363_T	367_G	1.499	0.97
535_L	583_R	1.498	0.97
315_L	568_I	1.496	0.97
196_V	214_E	1.481	0.97
144_H	171_C	1.477	0.97
234_T	261_S	1.473	0.97
372_G	405_E	1.466	0.97
520_A	577_L	1.461	0.97
143_K	181_R	1.459	0.97
232_K	265_S	1.459	0.97
331_R	567_R	1.459	0.97
456_S	481_K	1.454	0.97
316_A	442_A	1.450	0.97
530_S	533_K	1.447	0.96
565_L	586_A	1.413	0.96
149_C	155_W	1.412	0.96
487_Q	490_E	1.409	0.96
316_A	400_I	1.409	0.96
367_G	388_L	1.398	0.96
644_K	647_D	1.380	0.95
274_I	282_I	1.380	0.95
170_I	177_P	1.377	0.95
197_I	233_V	1.371	0.95
618_K	623_R	1.364	0.95
569_S	586_A	1.363	0.95
321_V	525_T	1.346	0.95
211_R	417_I	1.345	0.95
320_G	574_K	1.344	0.95
286_A	291_I	1.337	0.94
33_R	42_K	1.335	0.94
14_F	22_K	1.333	0.94
147_P	155_W	1.330	0.94
535_L	590_I	1.325	0.94
494_Y	498_V	1.314	0.94
372_G	473_R	1.308	0.94
501_G	504_T	1.308	0.94
282_I	512_T	1.306	0.94
20_T	55_F	1.304	0.94
148_D	179_Q	1.301	0.94
14_F	21_F	1.300	0.94
153_F	157_E	1.293	0.93
292_R	572_Y	1.293	0.93
352_F	510_I	1.292	0.93
636_L	639_S	1.290	0.93
123_I	257_M	1.289	0.93
630_I	633_I	1.287	0.93
540_F	544_R	1.285	0.93
651_E	654_Q	1.283	0.93
168_P	171_C	1.282	0.93
331_R	405_E	1.280	0.93
314_A	318_F	1.278	0.93
292_R	588_R	1.276	0.93
292_R	591_N	1.270	0.93
538_D	542_E	1.268	0.93
620_K	623_R	1.265	0.93
375_A	428_I	1.257	0.92
27_Q	32_E	1.254	0.92
147_P	157_E	1.250	0.92
47_I	74_L	1.250	0.92
100_I	260_S	1.250	0.92
199_E	207_G	1.235	0.92
322_P	329_R	1.234	0.92
632_I	636_L	1.232	0.92
539_F	542_E	1.228	0.92
191_D	563_E	1.223	0.91
18_L	22_K	1.222	0.91
312_A	476_L	1.220	0.91
658_E	662_I	1.215	0.91
332_G	417_I	1.213	0.91
419_E	427_S	1.205	0.91
331_R	473_R	1.203	0.91
81_H	84_Q	1.202	0.91
122_T	232_K	1.200	0.91
233_V	259_V	1.198	0.91
586_A	596_F	1.194	0.90
536_I	565_L	1.193	0.90
293_D	297_S	1.193	0.90
524_V	577_L	1.190	0.90
290_W	297_S	1.189	0.90
19_T	84_Q	1.183	0.90
371_A	386_Y	1.183	0.90
476_L	592_I	1.182	0.90
405_E	448_N	1.179	0.90
568_I	572_Y	1.176	0.90
463_N	479_I	1.174	0.90
320_G	570_E	1.171	0.89
409_M	423_Q	1.167	0.89
372_G	560_R	1.160	0.89
150_M	155_W	1.159	0.89
315_L	571_A	1.159	0.89
110_R	207_G	1.156	0.89
340_G	346_K	1.151	0.89
288_D	508_I	1.146	0.88
141_T	183_I	1.144	0.88
657_I	662_I	1.143	0.88
603_D	607_G	1.141	0.88
195_A	225_A	1.141	0.88
648_I	662_I	1.140	0.88
131_T	400_I	1.135	0.88
243_S	246_K	1.135	0.88
621_S	626_M	1.132	0.88
338_I	444_I	1.131	0.88
367_G	418_H	1.130	0.88
603_D	606_S	1.127	0.88
292_R	311_E	1.126	0.88
280_K	284_D	1.126	0.88
649_L	653_Q	1.125	0.87
630_I	636_L	1.123	0.87
290_W	294_R	1.120	0.87
467_P	470_I	1.117	0.87
542_E	545_K	1.117	0.87
500_S	504_T	1.114	0.87
49_F	60_A	1.110	0.87
389_E	423_Q	1.106	0.87
625_K	636_L	1.105	0.87
295_I	513_L	1.105	0.87
645_V	649_L	1.103	0.86
317_L	357_A	1.101	0.86
413_D	416_A	1.100	0.86
72_P	75_E	1.100	0.86
657_I	661_N	1.100	0.86
30_Y	51_D	1.097	0.86
79_Y	95_K	1.094	0.86
297_S	307_W	1.094	0.86
321_V	574_K	1.092	0.86
363_T	423_Q	1.089	0.86
75_E	98_V	1.081	0.85
335_H	426_V	1.080	0.85
624_E	634_D	1.077	0.85
535_L	586_A	1.070	0.85
413_D	418_H	1.070	0.85
652_A	657_I	1.068	0.85
63_I	70_I	1.068	0.85
370_A	570_E	1.067	0.85
364_T	367_G	1.063	0.84
218_E	258_K	1.060	0.84
152_E	186_K	1.059	0.84
19_T	22_K	1.058	0.84
68_K	238_D	1.057	0.84
433_I	438_N	1.057	0.84
213_L	257_M	1.056	0.84
286_A	516_Y	1.050	0.84
420_A	470_I	1.043	0.83
293_D	307_W	1.037	0.83
183_I	186_K	1.036	0.83
473_R	560_R	1.036	0.83
197_I	215_I	1.034	0.83
190_I	219_D	1.034	0.83
294_R	571_A	1.032	0.83
419_E	425_T	1.031	0.82
107_I	116_D	1.031	0.82
584_E	587_E	1.028	0.82
47_I	77_A	1.024	0.82
32_E	36_E	1.024	0.82
207_G	210_P	1.024	0.82
42_K	45_L	1.021	0.82
331_R	560_R	1.017	0.82
363_T	368_S	1.013	0.81
626_M	630_I	1.012	0.81
346_K	404_D	1.012	0.81
207_G	359_R	1.011	0.81
536_I	566_I	1.010	0.81
633_I	636_L	1.010	0.81
658_E	661_N	1.008	0.81
652_A	655_V	1.007	0.81
66_N	69_I	1.004	0.81
625_K	631_E	1.004	0.81
108_E	111_K	1.001	0.81
406_I	445_A	0.998	0.80
62_E	70_I	0.992	0.80
61_Y	65_N	0.990	0.80
28_N	31_I	0.989	0.80
199_E	389_E	0.987	0.80
276_E	361_V	0.985	0.79
113_R	116_D	0.985	0.79
48_E	101_V	0.982	0.79
199_E	227_P	0.982	0.79
366_K	420_A	0.981	0.79
614_I	617_G	0.981	0.79
112_I	213_L	0.977	0.79
14_F	19_T	0.972	0.79
629_I	657_I	0.968	0.78
35_N	39_A	0.966	0.78
363_T	413_D	0.965	0.78
142_Y	359_R	0.965	0.78
120_L	234_T	0.963	0.78
586_A	590_I	0.963	0.78
448_N	473_R	0.961	0.78
406_I	447_G	0.961	0.78
196_V	429_A	0.960	0.78
634_D	638_V	0.960	0.78
87_P	91_R	0.959	0.78
42_K	224_S	0.957	0.77
618_K	626_M	0.956	0.77
339_I	390_A	0.954	0.77
282_I	516_Y	0.954	0.77
275_S	515_K	0.953	0.77
317_L	521_R	0.953	0.77
313_L	336_I	0.946	0.77
136_R	218_E	0.944	0.77
235_G	257_M	0.942	0.76
331_R	372_G	0.942	0.76
444_I	592_I	0.940	0.76
405_E	560_R	0.939	0.76
296_I	299_I	0.934	0.76
396_A	401_A	0.933	0.76
253_F	388_L	0.931	0.76
396_A	416_A	0.929	0.75
294_R	508_I	0.928	0.75
291_I	508_I	0.926	0.75
67_T	519_Y	0.926	0.75
559_P	596_F	0.924	0.75
473_R	567_R	0.924	0.75
377_V	386_Y	0.923	0.75
644_K	648_I	0.920	0.75
389_E	397_D	0.915	0.74
628_K	635_S	0.914	0.74
232_K	263_E	0.913	0.74
372_G	567_R	0.912	0.74
418_H	438_N	0.910	0.74
94_E	100_I	0.910	0.74
388_L	414_R	0.910	0.74
45_L	78_L	0.908	0.74
359_R	401_A	0.908	0.74
17_F	22_K	0.908	0.74
351_Q	362_Y	0.907	0.74
137_I	189_L	0.905	0.73
262_I	273_I	0.905	0.73
405_E	567_R	0.905	0.73
625_K	634_D	0.905	0.73
621_S	629_I	0.904	0.73
207_G	211_R	0.904	0.73
17_F	30_Y	0.901	0.73
472_S	558_T	0.900	0.73
198_Q	210_P	0.900	0.73
333_D	409_M	0.899	0.73
446_A	452_G	0.896	0.73
36_E	42_K	0.895	0.73
227_P	395_L	0.894	0.72
142_Y	168_P	0.893	0.72
339_I	593_M	0.892	0.72
151_Q	172_P	0.890	0.72
309_L	344_T	0.888	0.72
625_K	628_K	0.885	0.72
60_A	64_I	0.882	0.71
175_G	178_G	0.881	0.71
308_E	588_R	0.881	0.71
422_E	473_R	0.881	0.71
211_R	499_H	0.880	0.71
369_T	592_I	0.880	0.71
341_D	347_S	0.879	0.71
71_L	100_I	0.877	0.71
501_G	507_I	0.877	0.71
314_A	575_M	0.872	0.71
414_R	418_H	0.871	0.71
143_K	150_M	0.871	0.71
282_I	577_L	0.870	0.70
653_Q	656_G	0.867	0.70
392_A	463_N	0.866	0.70
282_I	515_K	0.865	0.70
409_M	447_G	0.864	0.70
147_P	181_R	0.863	0.70
278_D	282_I	0.860	0.70
57_E	61_Y	0.860	0.70
392_A	397_D	0.859	0.69
293_D	296_I	0.857	0.69
41_R	98_V	0.857	0.69
646_K	660_S	0.856	0.69
84_Q	543_M	0.855	0.69
380_E	383_T	0.854	0.69
652_A	662_I	0.854	0.69
69_I	85_L	0.853	0.69
340_G	348_Q	0.852	0.69
32_E	35_N	0.852	0.69
380_E	432_G	0.851	0.69
303_I	309_L	0.850	0.69
645_V	651_E	0.850	0.69
446_A	478_F	0.849	0.69
205_P	335_H	0.849	0.69
625_K	633_I	0.849	0.69
47_I	52_V	0.848	0.68
194_K	214_E	0.847	0.68
45_L	485_G	0.845	0.68
141_T	186_K	0.844	0.68
625_K	629_I	0.844	0.68
18_L	24_N	0.843	0.68
339_I	597_L	0.843	0.68
646_K	650_K	0.841	0.68
417_I	452_G	0.841	0.68
426_V	443_V	0.841	0.68
389_E	558_T	0.841	0.68
333_D	424_Q	0.837	0.67
453_R	484_P	0.836	0.67
512_T	515_K	0.836	0.67
603_D	617_G	0.833	0.67
564_A	570_E	0.832	0.67
46_I	99_R	0.831	0.67
149_C	401_A	0.831	0.67
318_F	524_V	0.830	0.67
348_Q	397_D	0.827	0.67
419_E	429_A	0.826	0.66
147_P	150_M	0.823	0.66
333_D	499_H	0.822	0.66
283_K	287_K	0.818	0.66
497_D	501_G	0.818	0.66
191_D	323_K	0.817	0.66
150_M	157_E	0.816	0.65
623_R	627_M	0.816	0.65
22_K	28_N	0.812	0.65
569_S	572_Y	0.811	0.65
379_R	564_A	0.808	0.65
75_E	97_H	0.807	0.65
423_Q	427_S	0.807	0.65
463_N	466_L	0.806	0.64
30_Y	34_I	0.804	0.64
153_F	156_P	0.801	0.64
343_G	446_A	0.801	0.64
227_P	345_A	0.800	0.64
130_V	195_A	0.800	0.64
318_F	574_K	0.800	0.64
449_P	454_Y	0.799	0.64
22_K	26_N	0.799	0.64
283_K	519_Y	0.798	0.64
343_G	347_S	0.796	0.64
501_G	505_K	0.795	0.63
502_K	506_N	0.794	0.63
232_K	566_I	0.793	0.63
136_R	142_Y	0.792	0.63
357_A	389_E	0.792	0.63
16_E	24_N	0.792	0.63
420_A	563_E	0.791	0.63
363_T	392_A	0.788	0.63
282_I	291_I	0.787	0.63
642_C	651_E	0.785	0.62
644_K	652_A	0.784	0.62
88_T	92_D	0.784	0.62
648_I	656_G	0.783	0.62
316_A	336_I	0.783	0.62
640_S	655_V	0.782	0.62
423_Q	431_A	0.778	0.62
47_I	82_I	0.776	0.62
79_Y	83_L	0.776	0.62
411_D	414_R	0.775	0.61
210_P	348_Q	0.773	0.61
348_Q	403_I	0.771	0.61
618_K	621_S	0.771	0.61
17_F	51_D	0.769	0.61
625_K	632_I	0.768	0.61
421_M	443_V	0.767	0.61
621_S	627_M	0.767	0.61
357_A	360_A	0.767	0.61
110_R	199_E	0.766	0.61
37_L	41_R	0.763	0.60
626_M	637_A	0.762	0.60
355_R	369_T	0.762	0.60
403_I	417_I	0.762	0.60
348_Q	409_M	0.761	0.60
28_N	32_E	0.761	0.60
303_I	447_G	0.761	0.60
638_V	642_C	0.761	0.60
142_Y	253_F	0.758	0.60
648_I	652_A	0.757	0.60
623_R	629_I	0.756	0.60
293_D	311_E	0.755	0.59
458_R	463_N	0.755	0.59
198_Q	207_G	0.753	0.59
413_D	417_I	0.752	0.59
51_D	55_F	0.750	0.59
634_D	637_A	0.749	0.59
33_R	37_L	0.748	0.59
129_K	380_E	0.747	0.59
16_E	19_T	0.747	0.59
619_P	625_K	0.746	0.59
24_N	574_K	0.745	0.58
307_W	628_K	0.744	0.58
210_P	397_D	0.744	0.58
401_A	463_N	0.740	0.58
337_L	477_I	0.739	0.58
34_I	87_P	0.739	0.58
16_E	23_G	0.736	0.57
397_D	438_N	0.735	0.57
524_V	574_K	0.734	0.57
347_S	350_L	0.733	0.57
30_Y	33_R	0.733	0.57
624_E	628_K	0.733	0.57
640_S	646_K	0.732	0.57
198_Q	397_D	0.732	0.57
341_D	346_K	0.731	0.57
433_I	437_L	0.731	0.57
539_F	594_R	0.730	0.57
632_I	649_L	0.730	0.57
361_V	558_T	0.729	0.57
647_D	651_E	0.728	0.57
304_Y	315_L	0.728	0.57
629_I	635_S	0.728	0.57
87_P	90_Q	0.727	0.57
127_L	225_A	0.727	0.57
556_L	559_P	0.725	0.56
513_L	524_V	0.725	0.56
649_L	654_Q	0.724	0.56
262_I	548_S	0.720	0.56
350_L	419_E	0.719	0.56
631_E	635_S	0.718	0.56
199_E	408_K	0.718	0.56
627_M	633_I	0.716	0.55
112_I	286_A	0.716	0.55
189_L	492_A	0.716	0.55
353_I	360_A	0.716	0.55
63_I	133_V	0.715	0.55
340_G	347_S	0.713	0.55
318_F	517_I	0.713	0.55
624_E	639_S	0.713	0.55
374_T	392_A	0.711	0.55
67_T	71_L	0.710	0.55
16_E	22_K	0.709	0.55
79_Y	313_L	0.708	0.55
118_G	134_K	0.705	0.54
366_K	418_H	0.705	0.54
152_E	183_I	0.702	0.54
390_A	479_I	0.701	0.54
635_S	658_E	0.701	0.54
319_G	340_G	0.701	0.54
493_N	497_D	0.698	0.54
432_G	473_R	0.698	0.54
18_L	31_I	0.698	0.54
141_T	152_E	0.697	0.53
303_I	408_K	0.696	0.53
313_L	393_L	0.696	0.53
629_I	632_I	0.695	0.53
15_I	22_K	0.695	0.53
373_L	405_E	0.694	0.53
632_I	652_A	0.694	0.53
332_G	375_A	0.693	0.53
571_A	597_L	0.692	0.53
130_V	426_V	0.692	0.53
576_A	582_T	0.691	0.53
332_G	363_T	0.691	0.53
641_E	644_K	0.691	0.53
377_V	439_A	0.689	0.53
199_E	419_E	0.689	0.53
135_E	439_A	0.689	0.53
67_T	236_I	0.688	0.52
121_I	545_K	0.688	0.52
503_S	506_N	0.688	0.52
23_G	29_K	0.687	0.52
620_K	624_E	0.687	0.52
63_I	633_I	0.687	0.52
627_M	632_I	0.686	0.52
646_K	654_Q	0.686	0.52
407_D	447_G	0.685	0.52
356_V	360_A	0.682	0.52
312_A	336_I	0.682	0.52
291_I	597_L	0.682	0.52
128_V	226_R	0.681	0.52
645_V	648_I	0.681	0.52
375_A	408_K	0.681	0.52
650_K	657_I	0.680	0.52
333_D	361_V	0.679	0.52
217_L	224_S	0.679	0.52
49_F	63_I	0.678	0.51
295_I	540_F	0.678	0.51
292_R	576_A	0.677	0.51
332_G	574_K	0.677	0.51
642_C	648_I	0.677	0.51
151_Q	173_K	0.676	0.51
323_K	442_A	0.676	0.51
540_F	568_I	0.676	0.51
443_V	456_S	0.674	0.51
598_E	601_G	0.674	0.51
19_T	24_N	0.674	0.51
112_I	521_R	0.674	0.51
291_I	576_A	0.673	0.51
19_T	23_G	0.671	0.51
207_G	423_Q	0.669	0.50
416_A	452_G	0.667	0.50
572_Y	591_N	0.667	0.50
458_R	565_L	0.666	0.50
277_E	294_R	0.666	0.50
315_L	467_P	0.664	0.50
305_G	452_G	0.663	0.50
410_R	416_A	0.662	0.50
330_I	417_I	0.661	0.50
469_T	570_E	0.661	0.50
299_I	349_M	0.660	0.49
342_P	448_N	0.660	0.49
460_V	464_I	0.659	0.49
71_L	98_V	0.659	0.49
149_C	153_F	0.659	0.49
139_K	154_E	0.658	0.49
195_A	262_I	0.658	0.49
363_T	417_I	0.657	0.49
92_D	121_I	0.657	0.49
45_L	98_V	0.656	0.49
335_H	366_K	0.656	0.49
205_P	211_R	0.656	0.49
229_D	436_K	0.656	0.49
342_P	347_S	0.655	0.49
24_N	29_K	0.655	0.49
110_R	492_A	0.655	0.49
68_K	72_P	0.655	0.49
226_R	362_Y	0.654	0.49
371_A	377_V	0.653	0.49
652_A	656_G	0.653	0.49
641_E	660_S	0.653	0.49
142_Y	315_L	0.652	0.49
619_P	632_I	0.652	0.49
149_C	570_E	0.651	0.49
572_Y	576_A	0.651	0.49
282_I	326_E	0.651	0.49
335_H	345_A	0.649	0.48
333_D	416_A	0.648	0.48
640_S	644_K	0.648	0.48
624_E	632_I	0.647	0.48
210_P	562_L	0.647	0.48
120_L	341_D	0.647	0.48
201_P	300_A	0.646	0.48
198_Q	440_R	0.646	0.48
644_K	660_S	0.645	0.48
633_I	637_A	0.645	0.48
315_L	575_M	0.645	0.48
354_S	426_V	0.644	0.48
179_Q	457_E	0.644	0.48
23_G	26_N	0.644	0.48
367_G	413_D	0.644	0.48
557_I	561_Q	0.643	0.48
468_P	478_F	0.643	0.48
534_N	537_T	0.641	0.47
417_I	470_I	0.641	0.47
619_P	622_A	0.640	0.47
477_I	561_Q	0.639	0.47
295_I	575_M	0.639	0.47
370_A	420_A	0.638	0.47
292_R	575_M	0.638	0.47
343_G	393_L	0.637	0.47
509_D	528_I	0.636	0.47
645_V	660_S	0.635	0.47
626_M	633_I	0.635	0.47
15_I	20_T	0.634	0.47
89_Y	531_E	0.633	0.47
95_K	102_G	0.631	0.46
620_K	634_D	0.630	0.46
323_K	330_I	0.628	0.46
370_A	561_Q	0.628	0.46
628_K	633_I	0.628	0.46
554_P	596_F	0.627	0.46
406_I	423_Q	0.627	0.46
88_T	91_R	0.626	0.46
41_R	45_L	0.626	0.46
621_S	637_A	0.626	0.46
407_D	449_P	0.626	0.46
437_L	488_D	0.625	0.46
367_G	375_A	0.625	0.46
371_A	420_A	0.624	0.46
624_E	630_I	0.624	0.46
403_I	421_M	0.622	0.45
439_A	449_P	0.622	0.45
366_K	407_D	0.621	0.45
282_I	345_A	0.620	0.45
487_Q	565_L	0.620	0.45
210_P	437_L	0.619	0.45
168_P	180_F	0.619	0.45
311_E	591_N	0.618	0.45
405_E	422_E	0.618	0.45
62_E	69_I	0.616	0.45
44_S	49_F	0.615	0.45
17_F	20_T	0.614	0.45
312_A	413_D	0.614	0.45
364_T	414_R	0.613	0.45
120_L	137_I	0.613	0.45
294_R	297_S	0.613	0.45
455_I	463_N	0.613	0.45
288_D	297_S	0.613	0.45
96_V	100_I	0.612	0.44
385_E	463_N	0.611	0.44
620_K	627_M	0.610	0.44
306_H	309_L	0.610	0.44
617_G	632_I	0.609	0.44
98_V	486_E	0.608	0.44
50_S	369_T	0.607	0.44
416_A	521_R	0.607	0.44
26_N	30_Y	0.607	0.44
115_T	530_S	0.606	0.44
274_I	291_I	0.605	0.44
402_V	406_I	0.605	0.44
323_K	333_D	0.604	0.44
98_V	504_T	0.604	0.44
351_Q	355_R	0.604	0.44
152_E	157_E	0.604	0.44
565_L	593_M	0.604	0.44
210_P	563_E	0.603	0.44
561_Q	570_E	0.603	0.44
455_I	502_K	0.602	0.43
465_N	599_S	0.602	0.43
317_L	565_L	0.602	0.43
15_I	21_F	0.602	0.43
369_T	447_G	0.601	0.43
482_D	544_R	0.601	0.43
528_I	566_I	0.600	0.43
292_R	296_I	0.600	0.43
359_R	393_L	0.599	0.43
199_E	447_G	0.599	0.43
240_K	491_L	0.598	0.43
191_D	570_E	0.598	0.43
389_E	562_L	0.598	0.43
620_K	631_E	0.597	0.43
357_A	388_L	0.596	0.43
340_G	408_K	0.596	0.43
404_D	448_N	0.595	0.43
375_A	418_H	0.595	0.43
276_E	521_R	0.595	0.43
628_K	637_A	0.595	0.43
655_V	661_N	0.595	0.43
365_G	409_M	0.595	0.43
635_S	646_K	0.594	0.43
641_E	651_E	0.594	0.43
51_D	514_R	0.593	0.42
252_V	286_A	0.593	0.42
440_R	472_S	0.592	0.42
405_E	432_G	0.591	0.42
21_F	24_N	0.591	0.42
300_A	375_A	0.591	0.42
275_S	282_I	0.590	0.42
316_A	657_I	0.590	0.42
421_M	429_A	0.590	0.42
618_K	629_I	0.589	0.42
150_M	153_F	0.588	0.42
341_D	452_G	0.588	0.42
262_I	398_G	0.588	0.42
309_L	338_I	0.587	0.42
409_M	413_D	0.587	0.42
337_L	441_A	0.587	0.42
23_G	27_Q	0.586	0.42
372_G	430_K	0.586	0.42
430_K	475_D	0.586	0.42
173_K	176_K	0.586	0.42
388_L	393_L	0.585	0.42
392_A	401_A	0.585	0.42
117_I	599_S	0.584	0.42
643_A	647_D	0.584	0.42
343_G	515_K	0.584	0.42
390_A	558_T	0.583	0.41
369_T	372_G	0.583	0.41
249_S	253_F	0.583	0.41
233_V	575_M	0.582	0.41
624_E	629_I	0.581	0.41
377_V	463_N	0.580	0.41
517_I	520_A	0.580	0.41
375_A	407_D	0.579	0.41
647_D	653_Q	0.578	0.41
459_P	553_S	0.578	0.41
632_I	654_Q	0.578	0.41
40_Y	197_I	0.578	0.41
230_R	469_T	0.577	0.41
195_A	233_V	0.577	0.41
192_W	364_T	0.577	0.41
644_K	651_E	0.576	0.41
197_I	213_L	0.576	0.41
236_I	260_S	0.576	0.41
101_V	261_S	0.575	0.41
83_L	90_Q	0.575	0.41
314_A	420_A	0.574	0.41
425_T	438_N	0.574	0.41
195_A	296_I	0.574	0.41
207_G	397_D	0.574	0.41
640_S	648_I	0.573	0.40
213_L	336_I	0.573	0.40
362_Y	427_S	0.573	0.40
77_A	568_I	0.572	0.40
379_R	427_S	0.571	0.40
139_K	188_K	0.571	0.40
198_Q	427_S	0.570	0.40
227_P	479_I	0.570	0.40
178_G	371_A	0.569	0.40
653_Q	662_I	0.569	0.40
359_R	415_V	0.567	0.40
347_S	421_M	0.566	0.40
597_L	600_V	0.564	0.40
635_S	638_V	0.564	0.40
49_F	52_V	0.563	0.39
403_I	454_Y	0.562	0.39
408_K	447_G	0.562	0.39
348_Q	440_R	0.561	0.39
648_I	653_Q	0.561	0.39
141_T	154_E	0.560	0.39
634_D	640_S	0.560	0.39
405_E	449_P	0.560	0.39
418_H	423_Q	0.560	0.39
426_V	469_T	0.559	0.39
33_R	274_I	0.559	0.39
149_C	168_P	0.558	0.39
331_R	346_K	0.558	0.39
537_T	565_L	0.557	0.39
366_K	375_A	0.557	0.39
406_I	409_M	0.556	0.39
112_I	237_L	0.555	0.39
43_K	219_D	0.555	0.39
625_K	638_V	0.555	0.39
211_R	415_V	0.555	0.39
392_A	405_E	0.554	0.38
314_A	479_I	0.553	0.38
31_I	35_N	0.552	0.38
626_M	636_L	0.552	0.38
418_H	433_I	0.551	0.38
126_I	300_A	0.551	0.38
254_D	257_M	0.551	0.38
299_I	304_Y	0.550	0.38
646_K	655_V	0.550	0.38
23_G	28_N	0.550	0.38
65_N	580_E	0.549	0.38
322_P	570_E	0.548	0.38
569_S	631_E	0.548	0.38
118_G	194_K	0.547	0.38
371_A	394_V	0.547	0.38
625_K	653_Q	0.546	0.38
241_Q	245_V	0.546	0.38
40_Y	582_T	0.546	0.38
419_E	423_Q	0.546	0.38
639_S	647_D	0.545	0.38
501_G	506_N	0.545	0.38
215_I	257_M	0.544	0.38
628_K	646_K	0.544	0.38
425_T	429_A	0.544	0.38
144_H	485_G	0.543	0.37
426_V	559_P	0.543	0.37
475_D	560_R	0.543	0.37
629_I	637_A	0.543	0.37
618_K	638_V	0.543	0.37
405_E	431_A	0.543	0.37
205_P	438_N	0.543	0.37
38_V	82_I	0.542	0.37
341_D	449_P	0.542	0.37
282_I	520_A	0.542	0.37
93_I	96_V	0.541	0.37
318_F	557_I	0.541	0.37
18_L	28_N	0.541	0.37
449_P	452_G	0.540	0.37
110_R	210_P	0.538	0.37
395_L	423_Q	0.538	0.37
142_Y	570_E	0.537	0.37
230_R	351_Q	0.537	0.37
452_G	499_H	0.536	0.37
129_K	314_A	0.536	0.37
356_V	471_L	0.535	0.37
618_K	625_K	0.535	0.37
83_L	100_I	0.535	0.37
625_K	635_S	0.534	0.37
199_E	423_Q	0.534	0.37
538_D	605_E	0.533	0.36
97_H	282_I	0.533	0.36
619_P	633_I	0.532	0.36
438_N	445_A	0.532	0.36
416_A	499_H	0.532	0.36
174_C	177_P	0.531	0.36
242_D	245_V	0.531	0.36
193_Q	403_I	0.531	0.36
389_E	395_L	0.531	0.36
342_P	560_R	0.530	0.36
638_V	644_K	0.530	0.36
312_A	564_A	0.529	0.36
33_R	36_E	0.529	0.36
204_V	345_A	0.527	0.36
395_L	517_I	0.527	0.36
633_I	652_A	0.526	0.36
152_E	155_W	0.526	0.36
433_I	480_L	0.526	0.36
24_N	27_Q	0.525	0.36
346_K	350_L	0.525	0.36
15_I	81_H	0.524	0.36
411_D	496_L	0.524	0.36
347_S	404_D	0.524	0.36
405_E	446_A	0.523	0.35
620_K	626_M	0.522	0.35
45_L	60_A	0.521	0.35
624_E	638_V	0.521	0.35
395_L	447_G	0.521	0.35
635_S	639_S	0.521	0.35
644_K	653_Q	0.521	0.35
403_I	406_I	0.520	0.35
117_I	232_K	0.520	0.35
285_L	288_D	0.520	0.35
204_V	390_A	0.520	0.35
613_T	617_G	0.520	0.35
113_R	134_K	0.519	0.35
410_R	428_I	0.519	0.35
56_N	74_L	0.518	0.35
52_V	131_T	0.518	0.35
208_Q	211_R	0.517	0.35
430_K	567_R	0.517	0.35
201_P	237_L	0.517	0.35
79_Y	82_I	0.517	0.35
138_Y	263_E	0.516	0.35
502_K	505_K	0.516	0.35
117_I	548_S	0.515	0.35
392_A	427_S	0.514	0.35
278_D	519_Y	0.513	0.34
633_I	640_S	0.513	0.34
39_A	517_I	0.513	0.34
494_Y	499_H	0.513	0.34
413_D	423_Q	0.512	0.34
430_K	560_R	0.512	0.34
134_K	192_W	0.511	0.34
56_N	152_E	0.511	0.34
139_K	157_E	0.511	0.34
651_E	655_V	0.510	0.34
380_E	390_A	0.509	0.34
199_E	440_R	0.509	0.34
368_S	444_I	0.509	0.34
222_V	339_I	0.509	0.34
274_I	278_D	0.508	0.34
363_T	375_A	0.508	0.34
646_K	653_Q	0.507	0.34
655_V	658_E	0.507	0.34
58_N	289_P	0.507	0.34
637_A	640_S	0.506	0.34
171_C	174_C	0.506	0.34
390_A	413_D	0.506	0.34
592_I	597_L	0.505	0.34
98_V	505_K	0.505	0.34
189_L	371_A	0.505	0.34
368_S	540_F	0.505	0.34
212_Q	229_D	0.504	0.34
15_I	32_E	0.504	0.34
396_A	399_G	0.503	0.34
253_F	327_D	0.503	0.34
197_I	543_M	0.502	0.33
329_R	332_G	0.502	0.33
112_I	257_M	0.502	0.33
48_E	509_D	0.501	0.33
640_S	647_D	0.500	0.33

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ja84	1	0.8513	100	0.328	Contact Map
4fdgB	1	0.8586	100	0.335	Contact Map
3ja87	1	0.8673	100	0.359	Contact Map
3ja83	1	0.8397	100	0.361	Contact Map
3ja82	1	0.8746	100	0.364	Contact Map
3ja85	1	0.8601	100	0.373	Contact Map
4r7yA	3	0.8528	100	0.378	Contact Map
3ja86	1	0.8455	100	0.391	Contact Map
3f8tA	1	0.6574	100	0.513	Contact Map
1ltlA	4	0.3499	100	0.719	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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