GREMLIN Database
RS19 - 30S ribosomal protein S19
UniProt: Q9UXA3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 140 (132)
Sequences: 392 (211)
Seq/√Len: 18.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
84_I106_I5.1911.00
58_R82_E4.4871.00
30_F34_L4.2001.00
17_K25_M3.4061.00
111_G116_T2.3740.95
14_Y35_P2.3710.95
53_L110_L2.3180.95
34_L38_Q2.0960.91
124_E127_L2.0370.90
38_Q109_Y1.8250.84
93_G122_H1.8170.83
42_L80_L1.7940.83
50_Q76_N1.7450.81
28_D31_I1.7230.80
117_T128_K1.7070.79
20_D23_L1.6650.77
44_R75_R1.6610.77
108_H111_G1.6020.75
133_S139_K1.5540.72
65_K70_I1.5510.72
8_E11_N1.5490.72
18_S21_E1.5190.71
128_K137_A1.5110.70
69_T89_A1.5060.70
132_S136_L1.5010.70
31_I91_Y1.4870.69
35_P38_Q1.4540.67
87_K98_E1.4400.66
123_G136_L1.4190.65
38_Q78_V1.3750.63
131_R136_L1.3700.62
10_K15_R1.3660.62
101_V110_L1.3600.62
30_F118_K1.3590.62
57_V102_T1.3450.61
77_L88_M1.3400.61
37_R113_Y1.3330.60
37_R112_E1.3240.60
42_L50_Q1.3070.59
131_R134_L1.3060.59
54_L82_E1.2750.57
42_L71_K1.2630.56
128_K132_S1.2570.56
109_Y112_E1.2030.52
46_F110_L1.1880.51
79_I88_M1.1790.51
130_T133_S1.1720.50
11_N117_T1.1680.50
36_S47_T1.1560.49
109_Y115_I1.1550.49
49_A67_N1.1510.49
108_H113_Y1.1450.49
25_M35_P1.1440.49
9_W117_T1.1410.48
30_F88_M1.1320.48
75_R93_G1.1100.46
46_F77_L1.1040.46
61_R86_L1.0950.46
16_G105_M1.0830.45
33_L38_Q1.0790.45
83_L136_L1.0380.42
110_L118_K1.0360.42
9_W137_A1.0170.41
57_V74_V1.0140.41
27_M35_P1.0070.40
127_L133_S0.9980.40
36_S42_L0.9950.39
100_T117_T0.9910.39
84_I101_V0.9840.39
25_M106_I0.9820.39
130_T135_F0.9770.38
40_R75_R0.9740.38
89_A98_E0.9640.38
70_I114_S0.9480.37
16_G112_E0.9450.37
92_N114_S0.9340.36
117_T124_E0.9290.36
113_Y130_T0.9270.35
39_R91_Y0.9270.35
63_E88_M0.9270.35
54_L77_L0.9250.35
25_M29_E0.9240.35
59_K77_L0.9230.35
90_V114_S0.8960.34
88_M101_V0.8910.33
54_L58_R0.8870.33
39_R112_E0.8870.33
57_V119_K0.8760.33
24_N32_K0.8740.33
26_P29_E0.8670.32
83_L112_E0.8550.31
87_K99_F0.8450.31
10_K125_P0.8400.31
129_A133_S0.8270.30
10_K41_S0.8250.30
122_H126_G0.8250.30
12_F53_L0.8230.30
128_K138_M0.8200.30
30_F33_L0.8200.30
40_R44_R0.8170.29
69_T76_N0.8160.29
36_S74_V0.8040.29
15_R75_R0.8040.29
128_K133_S0.8000.29
41_S50_Q0.7970.28
22_L47_T0.7950.28
102_T106_I0.7920.28
91_Y114_S0.7860.28
14_Y39_R0.7770.27
69_T98_E0.7740.27
43_K54_L0.7740.27
90_V110_L0.7700.27
78_V119_K0.7670.27
45_G83_L0.7660.27
30_F35_P0.7600.27
74_V82_E0.7580.27
71_K118_K0.7560.26
75_R122_H0.7520.26
49_A54_L0.7390.26
74_V125_P0.7340.25
30_F109_Y0.7290.25
55_E84_I0.7270.25
68_K102_T0.7260.25
9_W124_E0.7220.25
23_L136_L0.7200.25
134_L138_M0.7090.24
22_L106_I0.7090.24
135_F138_M0.7070.24
55_E88_M0.7050.24
70_I87_K0.7020.24
69_T121_E0.6920.23
117_T134_L0.6920.23
129_A139_K0.6880.23
28_D54_L0.6860.23
95_E98_E0.6780.23
21_E26_P0.6760.23
17_K33_L0.6710.23
93_G107_G0.6650.22
43_K79_I0.6560.22
34_L107_G0.6550.22
85_G100_T0.6540.22
112_E120_V0.6530.22
59_K63_E0.6520.22
28_D38_Q0.6490.22
74_V120_V0.6390.21
31_I43_K0.6360.21
15_R105_M0.6350.21
32_K52_H0.6330.21
47_T57_V0.6280.21
90_V96_F0.6260.21
94_K103_P0.6230.21
45_G96_F0.6230.21
63_E80_L0.6210.20
13_K19_I0.6150.20
27_M79_I0.6150.20
16_G83_L0.6090.20
21_E84_I0.6070.20
15_R84_I0.6070.20
20_D56_K0.6050.20
88_M114_S0.5990.20
99_F136_L0.5980.20
65_K68_K0.5960.19
58_R96_F0.5950.19
59_K130_T0.5940.19
37_R40_R0.5930.19
74_V109_Y0.5860.19
40_R107_G0.5850.19
124_E128_K0.5830.19
12_F19_I0.5700.18
9_W17_K0.5690.18
34_L51_R0.5680.18
11_N136_L0.5590.18
68_K71_K0.5590.18
80_L108_H0.5570.18
16_G107_G0.5560.18
57_V95_E0.5540.18
96_F129_A0.5510.18
29_E89_A0.5500.18
94_K120_V0.5470.18
127_L131_R0.5460.18
43_K50_Q0.5440.18
91_Y117_T0.5410.17
59_K74_V0.5410.17
97_V120_V0.5400.17
50_Q130_T0.5390.17
44_R61_R0.5290.17
10_K86_L0.5270.17
48_D52_H0.5220.17
109_Y116_T0.5140.16
69_T99_F0.5130.16
94_K114_S0.5130.16
67_N89_A0.5100.16
82_E114_S0.5090.16
54_L69_T0.5070.16
12_F72_T0.5060.16
124_E137_A0.5040.16
100_T113_Y0.5010.16
39_R122_H0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4w23P 1 0.6643 100 0.138 Contact Map
3j38P 1 0.8643 100 0.14 Contact Map
3zeyI 1 0.9286 100 0.16 Contact Map
3j7aX 1 0.6643 100 0.162 Contact Map
4ujpQ 1 0.8643 100 0.208 Contact Map
3j20T 1 0.7929 100 0.218 Contact Map
4bpeS 1 0.8286 100 0.227 Contact Map
3bbnS 1 0.6571 100 0.565 Contact Map
4kiyS 1 0.5643 100 0.576 Contact Map
3a1pB 1 0.6071 100 0.58 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0055 seconds.