GREMLIN Database
RS8 - 30S ribosomal protein S8
UniProt: Q9UX92 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 133 (129)
Sequences: 2877 (1350)
Seq/√Len: 118.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
111_K122_L3.7271.00
42_Q49_E3.5171.00
12_T15_Y3.1121.00
92_Y123_R3.1111.00
39_R43_K2.7781.00
36_N39_R2.7501.00
26_I62_T2.6341.00
43_K118_E2.5321.00
118_E122_L2.5151.00
10_A38_L2.4981.00
77_P133_Y2.3101.00
116_H120_A2.2591.00
7_L37_V2.1201.00
18_E73_G2.1201.00
9_N13_S2.0161.00
11_L130_G2.0131.00
38_L63_V1.8511.00
53_I62_T1.8401.00
35_I52_Y1.8151.00
6_P34_V1.8001.00
54_D59_G1.7931.00
47_V50_F1.7711.00
24_Q62_T1.7371.00
26_I60_K1.7081.00
10_A27_I1.6111.00
17_N25_A1.5981.00
91_D94_R1.5481.00
42_Q47_V1.4671.00
40_V113_V1.4611.00
33_L129_L1.4561.00
118_E121_R1.4131.00
41_M132_V1.3701.00
39_R50_F1.3581.00
30_A35_I1.3551.00
5_N80_P1.3411.00
105_I131_Y1.3311.00
79_Y131_Y1.3251.00
37_V113_V1.3091.00
86_M131_Y1.2941.00
31_S34_V1.2931.00
7_L33_L1.2911.00
27_I61_I1.2871.00
98_P105_I1.2600.99
95_R116_H1.2580.99
51_E62_T1.2340.99
68_R72_C1.2330.99
90_P95_R1.2190.99
24_Q64_Q1.1840.99
35_I61_I1.1600.99
68_R73_G1.1460.99
21_R71_K1.1420.99
51_E64_Q1.1150.99
30_A52_Y1.1040.99
39_R42_Q1.0650.98
35_I39_R1.0560.98
30_A59_G1.0490.98
55_D59_G1.0340.98
111_K124_I1.0300.98
10_A34_V1.0190.98
54_D57_R1.0190.98
42_Q50_F1.0190.98
77_P131_Y1.0050.97
27_I63_V1.0050.97
95_R107_V1.0010.97
57_R60_K0.9970.97
82_S89_L0.9930.97
77_P99_S0.9930.97
46_Y104_I0.9820.97
90_P107_V0.9800.97
6_P31_S0.9730.97
33_L113_V0.9530.96
18_E133_Y0.9420.96
95_R128_A0.9340.96
106_I130_G0.9300.96
52_Y59_G0.9250.96
97_L116_H0.9150.95
29_P34_V0.9140.95
35_I59_G0.8810.94
81_L88_A0.8730.94
17_N20_R0.8660.94
80_P87_I0.8650.94
114_M122_L0.8490.93
26_I53_I0.8440.93
48_G64_Q0.8440.93
55_D60_K0.8390.93
18_E68_R0.8390.93
90_P94_R0.8280.92
108_S127_V0.8210.92
105_I116_H0.8200.92
32_K35_I0.7970.91
114_M118_E0.7960.91
11_L15_Y0.7830.90
96_Y105_I0.7810.90
10_A37_V0.7780.90
90_P128_A0.7720.89
53_I57_R0.7680.89
45_G66_L0.7680.89
49_E64_Q0.7640.89
53_I60_K0.7610.89
7_L133_Y0.7560.88
67_G73_G0.7530.88
101_E116_H0.7480.88
21_R73_G0.7480.88
128_A131_Y0.7470.88
8_A34_V0.7460.88
111_K114_M0.7390.87
113_V129_L0.7310.87
83_Y89_L0.7310.87
99_S133_Y0.7310.87
66_L75_I0.7290.87
44_E118_E0.7260.86
55_D58_W0.7240.86
43_K114_M0.7230.86
35_I42_Q0.6980.84
13_S17_N0.6950.84
114_M124_I0.6940.84
18_E78_R0.6840.83
14_I78_R0.6780.82
96_Y131_Y0.6770.82
54_D58_W0.6720.82
38_L61_I0.6700.82
86_M90_P0.6680.81
4_V8_A0.6650.81
82_S127_V0.6620.81
68_R71_K0.6560.80
104_I132_V0.6470.79
37_V130_G0.6470.79
114_M119_A0.6390.79
46_Y102_I0.6340.78
98_P131_Y0.6330.78
13_S22_N0.6310.78
35_I50_F0.6270.77
37_V106_I0.6260.77
41_M106_I0.6250.77
14_I75_I0.6230.77
72_C76_T0.6180.76
77_P86_M0.6170.76
40_V130_G0.6160.76
86_M117_K0.6160.76
23_K48_G0.6160.76
24_Q51_E0.6150.76
40_V106_I0.6150.76
40_V104_I0.6070.75
96_Y120_A0.6060.75
56_G59_G0.6060.75
109_T114_M0.6030.74
87_I127_V0.6030.74
85_Q127_V0.6010.74
44_E115_S0.6000.74
27_I34_V0.5990.74
109_T112_G0.5950.73
90_P133_Y0.5940.73
8_A12_T0.5920.73
24_Q48_G0.5820.72
6_P113_V0.5810.72
23_K121_R0.5790.71
98_P104_I0.5790.71
14_I63_V0.5770.71
23_K68_R0.5770.71
76_T99_S0.5660.70
82_S85_Q0.5640.69
22_N25_A0.5620.69
71_K86_M0.5610.69
10_A63_V0.5600.69
45_G49_E0.5600.69
33_L38_L0.5580.69
108_S113_V0.5570.69
48_G88_A0.5570.69
38_L52_Y0.5560.68
41_M104_I0.5560.68
43_K121_R0.5500.68
32_K59_G0.5490.67
107_V128_A0.5460.67
97_L120_A0.5410.66
4_V13_S0.5400.66
50_F63_V0.5360.66
52_Y61_I0.5340.65
68_R76_T0.5260.64
110_S124_I0.5260.64
46_Y54_D0.5230.64
81_L131_Y0.5210.63
36_N51_E0.5190.63
77_P130_G0.5190.63
10_A88_A0.5160.63
20_R38_L0.5120.62
18_E74_P0.5110.62
4_V34_V0.5100.62
15_Y78_R0.5100.62
5_N8_A0.5090.62
93_V110_S0.5050.61
67_G75_I0.5040.61
99_S117_K0.5020.61
7_L36_N0.5010.60
53_I56_G0.5000.60
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4pdbA 1 0.9699 100 0.05 Contact Map
4rb5H 1 0.9774 100 0.071 Contact Map
1seiA 2 0.9774 100 0.081 Contact Map
3bbnH 1 0.985 100 0.099 Contact Map
1s03H 1 0.9549 100 0.103 Contact Map
3rf2A 1 0.9699 100 0.112 Contact Map
1i6uA 1 0.9323 100 0.172 Contact Map
4bpeH 1 0.9248 100 0.185 Contact Map
4ujpX 1 0.9248 100 0.213 Contact Map
3qd7X 1 0.4962 52.5 0.924 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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