GREMLIN Database
RL32 - 50S ribosomal protein L32e
UniProt: Q9UX90 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 138 (121)
Sequences: 537 (314)
Seq/√Len: 28.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
106_V129_L3.4801.00
85_Q107_T3.4131.00
105_I132_S3.2411.00
125_R134_E2.9221.00
106_V131_V2.6130.99
131_V134_E2.6060.99
118_L122_N2.5560.99
79_H85_Q2.4420.99
30_Y52_N2.2870.99
122_N126_E2.2330.98
123_K127_L2.1580.98
39_G42_E2.0860.97
79_H105_I1.9860.96
83_L130_K1.9690.96
57_K66_S1.9340.96
108_I112_V1.8980.95
51_D60_G1.8970.95
31_D35_F1.8460.95
39_G43_K1.8060.94
21_K71_L1.7860.94
123_K126_E1.7590.93
88_V131_V1.6790.91
29_R45_R1.6520.91
107_T132_S1.6380.90
47_P64_I1.6180.90
55_R117_R1.5350.87
95_V123_K1.5350.87
119_E122_N1.5040.86
89_H121_L1.4770.85
112_V120_I1.4460.83
32_S38_L1.4240.82
54_T62_P1.4090.82
89_H93_E1.3760.80
28_L42_E1.3710.80
30_Y48_Y1.3700.80
45_R55_R1.3540.79
16_I20_L1.3200.77
90_N112_V1.3020.76
38_L43_K1.2770.75
83_L125_R1.2550.74
13_I75_V1.2350.72
37_R42_E1.2160.71
97_V129_L1.2150.71
71_L75_V1.2080.71
25_P65_V1.1730.68
29_R55_R1.1700.68
38_L42_E1.1450.66
88_V116_K1.1440.66
108_I120_I1.1320.66
105_I130_K1.1190.65
124_A133_N1.1060.64
45_R49_G1.1020.63
90_N117_R1.0940.63
19_K22_A1.0920.63
54_T64_I1.0870.62
36_Y39_G1.0700.61
118_L128_G1.0660.61
44_W117_R1.0650.61
19_K78_F1.0400.59
52_N61_F0.9830.55
91_V120_I0.9630.53
109_S112_V0.9590.53
20_L75_V0.9580.53
94_L129_L0.9430.51
24_K71_L0.9420.51
55_R68_G0.9340.51
91_V94_L0.9290.50
84_R103_N0.9210.50
45_R133_N0.9070.49
81_S87_I0.9010.48
87_I95_V0.8740.46
87_I132_S0.8610.45
51_D54_T0.8550.45
30_Y37_R0.8540.45
120_I133_N0.8500.44
104_V116_K0.8430.44
50_R60_G0.8340.43
21_K24_K0.8280.43
53_K61_F0.8280.43
85_Q132_S0.8240.42
121_L131_V0.8240.42
70_R88_V0.8230.42
33_D51_D0.8180.42
115_K119_E0.8150.42
90_N93_E0.8130.41
86_V104_V0.8050.41
26_K30_Y0.7960.40
23_K91_V0.7920.40
45_R117_R0.7910.40
57_K64_I0.7810.39
104_V115_K0.7800.39
112_V117_R0.7780.39
46_R61_F0.7690.38
88_V133_N0.7640.38
35_F38_L0.7590.37
72_P77_G0.7550.37
89_H131_V0.7510.37
62_P103_N0.7490.37
83_L105_I0.7410.36
93_E97_V0.7380.36
13_I16_I0.7380.36
107_T110_S0.7350.36
50_R54_T0.7330.36
37_R100_Q0.7320.36
63_A69_Y0.7310.35
17_R78_F0.7310.35
19_K71_L0.7300.35
28_L32_S0.7250.35
59_R89_H0.7220.35
19_K75_V0.7180.35
33_D60_G0.7160.34
78_F115_K0.7150.34
20_L93_E0.7140.34
88_V108_I0.7070.34
73_K111_S0.6990.33
97_V110_S0.6970.33
47_P68_G0.6970.33
95_V126_E0.6910.33
54_T90_N0.6900.33
90_N109_S0.6860.32
106_V127_L0.6840.32
81_S105_I0.6680.31
84_R100_Q0.6590.31
17_R72_P0.6540.30
98_Q113_G0.6510.30
31_D34_K0.6480.30
53_K58_V0.6460.30
45_R76_R0.6460.30
79_H130_K0.6430.30
46_R118_L0.6350.29
30_Y35_F0.6350.29
20_L24_K0.6280.29
86_V115_K0.6230.28
19_K23_K0.6210.28
13_I20_L0.6180.28
77_G104_V0.6100.27
45_R120_I0.6100.27
32_S64_I0.6060.27
102_D107_T0.6050.27
34_K39_G0.5950.27
36_Y118_L0.5930.26
64_I69_Y0.5920.26
50_R56_L0.5850.26
15_V18_Q0.5840.26
36_Y52_N0.5800.26
44_W47_P0.5790.26
89_H114_F0.5770.25
76_R119_E0.5750.25
43_K76_R0.5700.25
31_D99_N0.5700.25
35_F125_R0.5680.25
33_D58_V0.5680.25
57_K60_G0.5600.24
49_G55_R0.5600.24
99_N107_T0.5520.24
96_K100_Q0.5510.24
51_D57_K0.5470.24
29_R52_N0.5410.23
60_G121_L0.5390.23
35_F46_R0.5360.23
29_R133_N0.5350.23
97_V112_V0.5340.23
14_Y22_A0.5250.23
45_R84_R0.5240.22
14_Y80_P0.5230.22
108_I116_K0.5170.22
37_R78_F0.5160.22
48_Y54_T0.5150.22
78_F84_R0.5140.22
100_Q114_F0.5140.22
29_R129_L0.5120.22
121_L129_L0.5120.22
72_P113_G0.5110.22
17_R25_P0.5100.22
92_N95_V0.5100.22
63_A105_I0.5100.22
87_I92_N0.5100.22
45_R116_K0.5080.22
94_L104_V0.5070.22
79_H103_N0.5040.21
20_L56_L0.5020.21
32_S43_K0.5000.21
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zf7i 1 0.913 100 0.085 Contact Map
4a17X 1 0.9058 100 0.086 Contact Map
4w20e 1 0.9275 100 0.087 Contact Map
3j61e 1 0.9203 100 0.088 Contact Map
1vx78 1 0.9058 100 0.093 Contact Map
4ujrR 1 0.9058 100 0.096 Contact Map
3j21b 1 0.9203 100 0.115 Contact Map
1vq8Y 1 0.9565 100 0.151 Contact Map
4o5aA 2 0.0072 31.8 0.941 Contact Map
3h5tA 2 0.3406 31.1 0.941 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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