GREMLIN Database
RL30 - 50S ribosomal protein L30P
UniProt: Q9UX86 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 158 (152)
Sequences: 687 (421)
Seq/√Len: 34.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
6_G35_T6.2821.00
51_V55_I4.5351.00
4_L105_G3.9131.00
59_E145_Y3.6281.00
64_T154_M3.0621.00
98_M112_L3.0171.00
27_L51_V2.9931.00
108_Y111_K2.9371.00
6_G154_M2.8701.00
75_T81_V2.7441.00
149_K152_E2.5751.00
137_Y149_K2.2920.99
63_D67_L2.2090.99
66_K96_D2.1460.99
77_K86_V2.0890.99
60_I65_L1.9840.98
5_L40_K1.9820.98
33_F129_F1.8870.97
23_T50_K1.8290.97
75_T116_F1.8140.96
56_T146_R1.7990.96
23_T47_M1.7810.96
83_D95_I1.7460.96
84_S87_K1.5890.93
7_I38_Y1.5010.90
20_I24_L1.4940.90
125_P128_G1.4910.90
42_S46_G1.4730.89
62_P100_K1.4270.88
57_W145_Y1.3880.86
16_A20_I1.3790.86
61_D67_L1.3490.85
7_I153_L1.3390.84
33_F72_R1.3320.84
65_L103_Y1.2890.82
49_N52_S1.2840.82
92_I101_Q1.2790.82
153_L157_M1.2780.81
28_R72_R1.2700.81
84_S97_A1.2690.81
22_E26_M1.2640.81
56_T145_Y1.2200.78
17_P20_I1.2110.78
93_E97_A1.2000.77
26_M47_M1.1980.77
85_Y89_V1.1880.76
137_Y140_K1.1850.76
87_K95_I1.1780.76
61_D155_R1.1590.75
40_K45_L1.1570.74
67_L155_R1.1440.74
130_K142_E1.1380.73
62_P66_K1.1240.72
100_K104_E1.1210.72
146_R151_N1.1180.72
69_I102_L1.1160.72
36_M113_D1.1120.71
31_Y34_N1.0790.69
83_D86_V1.0780.69
141_G144_G1.0700.68
25_N31_Y1.0410.66
33_F126_R1.0380.66
84_S88_E1.0310.66
35_T154_M1.0290.65
101_Q106_K1.0200.65
61_D151_N1.0110.64
125_P129_F1.0070.64
33_F124_P0.9930.63
76_V118_L0.9840.62
136_P139_N0.9760.61
114_E133_V0.9730.61
86_V95_I0.9700.61
8_I154_M0.9680.61
81_V116_F0.9650.60
18_W21_N0.9580.60
30_R119_P0.9530.59
18_W22_E0.9530.59
138_K147_G0.9510.59
142_E146_R0.9460.59
46_G134_K0.9450.59
128_G132_S0.9400.58
36_M119_P0.9330.58
11_R15_K0.9280.57
77_K80_K0.9260.57
129_F142_E0.9180.56
34_N119_P0.9110.56
21_N27_L0.9060.55
77_K98_M0.8980.55
27_L38_Y0.8930.54
69_I81_V0.8780.53
148_D152_E0.8760.53
50_K134_K0.8670.52
10_I55_I0.8670.52
67_L71_N0.8640.52
9_R146_R0.8620.52
47_M56_T0.8590.52
127_G136_P0.8530.51
11_R26_M0.8350.50
92_I112_L0.8300.49
60_I120_I0.8210.48
25_N30_R0.8150.48
43_Q104_E0.8130.48
7_I48_L0.8120.48
133_V136_P0.8100.47
40_K134_K0.8100.47
69_I113_D0.8080.47
42_S132_S0.8070.47
26_M104_E0.7970.46
10_I127_G0.7970.46
36_M86_V0.7930.46
45_L49_N0.7870.45
70_I83_D0.7870.45
80_K126_R0.7850.45
125_P141_G0.7840.45
9_R120_I0.7740.44
83_D151_N0.7730.44
20_I23_T0.7710.44
27_L55_I0.7710.44
21_N25_N0.7700.44
30_R34_N0.7660.44
152_E156_R0.7620.43
31_Y121_R0.7500.42
90_L108_Y0.7460.42
8_I23_T0.7440.42
75_T111_K0.7400.42
13_W148_D0.7350.41
10_I142_E0.7320.41
61_D64_T0.7280.41
38_Y44_I0.7260.40
86_V135_R0.7250.40
66_K88_E0.7230.40
81_V95_I0.7230.40
4_L9_R0.7180.40
62_P65_L0.7060.39
38_Y130_K0.7060.39
101_Q113_D0.7000.38
141_G153_L0.6980.38
135_R143_F0.6980.38
6_G64_T0.6960.38
8_I56_T0.6950.38
73_L117_K0.6950.38
69_I150_I0.6940.38
79_D86_V0.6900.37
62_P71_N0.6830.37
12_G24_L0.6820.37
88_E149_K0.6820.37
141_G146_R0.6800.37
20_I127_G0.6790.37
97_A100_K0.6690.36
144_G157_M0.6670.36
5_L59_E0.6620.35
46_G132_S0.6600.35
69_I116_F0.6560.35
18_W26_M0.6540.35
125_P157_M0.6540.35
14_A48_L0.6450.34
27_L41_T0.6440.34
4_L99_V0.6420.34
44_I113_D0.6420.34
33_F107_I0.6410.34
33_F130_K0.6370.33
67_L100_K0.6350.33
98_M102_L0.6320.33
123_H143_F0.6290.33
13_W34_N0.6270.33
109_L117_K0.6240.32
130_K138_K0.6230.32
56_T59_E0.6230.32
142_E145_Y0.6210.32
62_P116_F0.6190.32
74_E118_L0.6180.32
21_N70_I0.6160.32
37_V65_L0.6140.32
85_Y123_H0.6120.32
76_V80_K0.6100.31
71_N106_K0.6030.31
54_Y155_R0.6000.31
124_P135_R0.6000.31
5_L45_L0.5990.31
66_K71_N0.5990.31
38_Y127_G0.5970.30
23_T36_M0.5950.30
124_P129_F0.5930.30
41_T124_P0.5930.30
36_M77_K0.5890.30
8_I95_I0.5880.30
57_W146_R0.5860.30
65_L68_L0.5830.29
102_L137_Y0.5790.29
20_I126_R0.5780.29
28_R113_D0.5780.29
37_V102_L0.5740.29
10_I40_K0.5730.29
90_L111_K0.5710.29
87_K103_Y0.5620.28
8_I55_I0.5620.28
49_N147_G0.5530.27
76_V114_E0.5490.27
62_P103_Y0.5490.27
86_V108_Y0.5450.27
77_K119_P0.5440.27
132_S136_P0.5430.27
92_I100_K0.5420.27
144_G151_N0.5400.27
35_T64_T0.5320.26
69_I112_L0.5320.26
61_D71_N0.5320.26
46_G157_M0.5310.26
102_L109_L0.5300.26
27_L99_V0.5290.26
128_G141_G0.5280.26
62_P102_L0.5250.26
100_K109_L0.5230.25
67_L120_I0.5220.25
18_W41_T0.5210.25
82_S89_V0.5190.25
60_I97_A0.5180.25
132_S135_R0.5160.25
65_L105_G0.5160.25
33_F157_M0.5130.25
98_M103_Y0.5080.24
52_S57_W0.5070.24
37_V147_G0.5030.24
94_N109_L0.5030.24
124_P134_K0.5020.24
96_D109_L0.5010.24
7_I44_I0.5010.24
60_I84_S0.5000.24
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2zkrw 1 0.9557 100 0.093 Contact Map
3j65r 2 0.9937 100 0.101 Contact Map
3zf7w 1 0.9873 100 0.122 Contact Map
4a17V 1 0.9873 100 0.122 Contact Map
3j61F 1 0.9873 100 0.124 Contact Map
4ujqI 1 0.9937 100 0.125 Contact Map
1vx75 1 0.9937 100 0.125 Contact Map
3j39F 1 0.9873 100 0.126 Contact Map
4w20F 1 0.9873 100 0.127 Contact Map
3j21Y 1 0.981 100 0.136 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.007 seconds.