GREMLIN Database
PURL - Phosphoribosylformylglycinamidine synthase subunit PurL
UniProt: Q9UX24 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 709 (691)
Sequences: 3232 (1608)
Seq/√Len: 61.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
333_V345_S5.0081.00
612_L624_I4.9901.00
272_T327_E4.7401.00
93_F144_A4.6681.00
620_Y675_V4.1691.00
541_R548_V4.0551.00
458_L463_A4.0421.00
342_D345_S3.6941.00
274_D277_K3.6731.00
272_T337_R3.4971.00
312_C316_E3.3771.00
262_V325_I3.3651.00
603_V649_I3.3031.00
200_L321_P3.2711.00
309_K313_E3.0741.00
309_K312_C3.0231.00
591_S658_I2.9881.00
382_Y697_N2.9281.00
337_R342_D2.8711.00
387_H562_L2.8611.00
384_V390_L2.8551.00
445_E448_K2.8351.00
158_L396_A2.7721.00
209_A255_G2.7451.00
549_V671_I2.7041.00
623_E682_L2.6861.00
376_P379_S2.6841.00
548_V622_V2.6471.00
587_V662_S2.5851.00
449_G645_S2.5791.00
623_E674_R2.5681.00
307_N310_E2.5541.00
444_Y495_E2.5391.00
486_F511_F2.5211.00
680_N688_D2.5131.00
599_F615_I2.4881.00
310_E313_E2.4611.00
154_V418_A2.4521.00
381_I609_A2.4511.00
276_E339_I2.4361.00
394_G699_F2.3751.00
279_P323_S2.3631.00
379_S383_T2.3401.00
149_I237_L2.2621.00
416_D601_K2.2461.00
546_L598_T2.2431.00
493_I527_I2.2321.00
382_Y693_N2.2211.00
70_D180_K2.2211.00
454_A527_I2.2071.00
171_D526_L2.1791.00
195_L303_V2.1651.00
439_C489_A2.1601.00
536_K539_K2.1441.00
117_L174_A2.1301.00
539_K542_V2.1171.00
280_L290_V2.1051.00
378_E693_N2.0801.00
622_V681_I2.0781.00
312_C322_C2.0621.00
75_W179_R2.0031.00
662_S669_A2.0021.00
563_L637_I1.9981.00
287_P338_Y1.9951.00
77_V428_L1.9881.00
13_I29_I1.9871.00
378_E382_Y1.9871.00
549_V658_I1.9831.00
272_T335_K1.9761.00
612_L622_V1.9721.00
9_E40_K1.9721.00
546_L675_V1.9681.00
438_M449_G1.9561.00
599_F651_L1.9531.00
659_V669_A1.9511.00
113_K238_D1.9471.00
613_F681_I1.9461.00
590_D594_E1.9421.00
335_K342_D1.9351.00
362_K481_E1.9261.00
115_I420_V1.9191.00
308_V324_V1.9161.00
611_S648_F1.9151.00
652_T655_P1.8971.00
459_A589_I1.8881.00
44_I358_L1.8871.00
488_E491_R1.8861.00
104_I149_I1.8821.00
616_L622_V1.8781.00
546_L651_L1.8721.00
361_I487_V1.8681.00
48_S491_R1.8601.00
549_V659_V1.8581.00
689_Y694_I1.8571.00
611_S649_I1.8571.00
588_V597_I1.8571.00
50_S60_I1.8421.00
207_G210_S1.8271.00
700_N704_E1.8271.00
682_L688_D1.7911.00
613_F617_V1.7790.99
661_K665_K1.7700.99
547_Y671_I1.7680.99
274_D337_R1.7630.99
544_D677_K1.7550.99
696_D700_N1.7520.99
541_R622_V1.7430.99
161_D569_I1.7420.99
447_G486_F1.7410.99
598_T651_L1.7300.99
104_I174_A1.7300.99
601_K614_S1.7150.99
381_I613_F1.7140.99
690_N693_N1.6880.99
592_I597_I1.6860.99
615_I651_L1.6660.99
417_S461_V1.6590.99
125_N162_D1.6590.99
452_A645_S1.6520.99
623_E676_N1.6500.99
29_I350_V1.6490.99
163_T522_K1.6470.99
68_A78_V1.6360.99
119_D142_I1.6210.99
617_V698_Y1.6110.99
695_V699_F1.5940.99
267_N352_L1.5930.99
548_V651_L1.5880.99
425_G535_D1.5790.99
382_Y689_Y1.5640.99
382_Y694_I1.5620.99
157_E393_K1.5500.99
635_N638_E1.5480.99
389_D562_L1.5470.99
211_F216_L1.5420.99
332_P349_N1.5410.99
468_A503_P1.5390.98
48_S52_D1.5330.98
55_N464_R1.5240.98
494_G498_R1.5210.98
386_T697_N1.5210.98
381_I610_A1.5180.98
442_D572_Q1.5150.98
442_D573_A1.5120.98
386_T700_N1.5100.98
244_A310_E1.5080.98
543_E546_L1.5060.98
441_E573_A1.5010.98
482_V520_P1.4940.98
387_H566_I1.4880.98
17_L347_P1.4830.98
418_A421_S1.4810.98
324_V327_E1.4800.98
397_Y413_G1.4780.98
390_L610_A1.4750.98
392_S699_F1.4750.98
474_F489_A1.4700.98
597_I600_A1.4700.98
466_M469_V1.4690.98
54_P501_N1.4680.98
444_Y488_E1.4560.98
331_E335_K1.4410.98
418_A423_P1.4290.98
416_D604_S1.4280.98
118_M430_I1.4280.98
394_G398_S1.4230.97
669_A672_I1.4220.97
6_L357_F1.4210.97
171_D432_A1.4170.97
276_E338_Y1.4080.97
420_V423_P1.4030.97
70_D74_G1.3980.97
69_V467_V1.3970.97
89_A216_L1.3870.97
253_L261_A1.3860.97
313_E316_E1.3810.97
533_V537_L1.3800.97
598_T653_N1.3790.97
551_V650_V1.3780.97
27_R288_S1.3720.97
335_K345_S1.3720.97
73_D426_K1.3710.97
549_V669_A1.3710.97
609_A683_T1.3690.97
689_Y693_N1.3600.97
588_V650_V1.3580.97
410_V538_L1.3520.97
495_E499_F1.3430.96
76_A180_K1.3410.96
557_E644_S1.3360.96
290_V338_Y1.3330.96
603_V611_S1.3320.96
453_E604_S1.3310.96
650_V658_I1.3290.96
438_M645_S1.3270.96
15_K18_G1.3270.96
416_D420_V1.3230.96
652_T658_I1.3160.96
303_V308_V1.3130.96
464_R593_N1.3090.96
554_T644_S1.3040.96
287_P343_L1.3010.96
460_T600_A1.2990.96
602_D614_S1.2930.96
591_S597_I1.2910.96
385_L613_F1.2820.95
616_L681_I1.2820.95
410_V539_K1.2800.95
55_N466_M1.2720.95
46_L49_F1.2680.95
203_V289_D1.2660.95
537_L592_I1.2630.95
74_G180_K1.2600.95
585_S648_F1.2590.95
541_R615_I1.2540.95
591_S661_K1.2520.95
457_N602_D1.2490.95
582_L586_E1.2450.95
191_A198_A1.2440.95
53_S69_V1.2420.94
193_L303_V1.2410.94
248_E304_E1.2400.94
128_I165_N1.2370.94
429_A458_L1.2360.94
658_I662_S1.2350.94
587_V665_K1.2300.94
161_D440_A1.2280.94
243_I311_V1.2180.94
610_A614_S1.2180.94
609_A613_F1.2110.94
600_A648_F1.2110.94
587_V661_K1.2090.94
612_L672_I1.2090.94
553_Y581_D1.2060.94
268_G332_P1.2010.93
378_E689_Y1.2010.93
460_T648_F1.2000.93
304_E307_N1.1990.93
123_V135_L1.1980.93
551_V584_S1.1940.93
484_Y488_E1.1940.93
71_I422_L1.1930.93
246_K307_N1.1920.93
476_D485_T1.1900.93
363_N485_T1.1900.93
657_W660_E1.1890.93
556_K642_S1.1890.93
374_D637_I1.1820.93
541_R675_V1.1800.93
501_N582_L1.1770.93
543_E653_N1.1740.93
612_L649_I1.1690.92
596_K657_W1.1690.92
81_V526_L1.1680.92
374_D635_N1.1680.92
189_D304_E1.1660.92
329_T332_P1.1640.92
616_L691_L1.1560.92
442_D445_E1.1530.92
7_P11_D1.1510.92
676_N679_T1.1450.92
375_L380_A1.1440.92
605_R614_S1.1430.92
385_L694_I1.1410.92
588_V648_F1.1410.92
453_E602_D1.1410.92
336_F344_V1.1390.91
81_V432_A1.1300.91
534_Q593_N1.1290.91
395_W399_Q1.1290.91
625_S684_I1.1260.91
554_T557_E1.1240.91
118_M173_A1.1220.91
272_T331_E1.1210.91
617_V695_V1.1200.91
88_S138_I1.1180.91
388_P391_V1.1170.91
383_T567_F1.1150.91
56_V59_G1.1140.91
464_R534_Q1.1120.90
56_V60_I1.1120.90
193_L324_V1.1110.90
179_R182_K1.1070.90
458_L469_V1.1070.90
554_T647_R1.1050.90
435_N453_E1.1010.90
161_D437_D1.1010.90
89_A211_F1.0990.90
417_S431_K1.0990.90
441_E571_S1.0960.90
464_R589_I1.0950.90
439_C450_I1.0940.90
171_D470_D1.0910.90
137_N140_A1.0900.90
265_I302_A1.0880.89
164_Y434_A1.0860.89
348_T352_L1.0860.89
418_A422_L1.0850.89
452_A581_D1.0850.89
431_K454_A1.0830.89
76_A178_V1.0830.89
282_V285_M1.0810.89
550_S603_V1.0780.89
337_R340_G1.0780.89
136_K140_A1.0750.89
48_S494_G1.0750.89
429_A463_A1.0700.89
603_V608_L1.0670.89
692_K695_V1.0660.88
548_V603_V1.0660.88
28_V346_L1.0650.88
193_L327_E1.0640.88
359_W478_K1.0630.88
469_V528_V1.0610.88
117_L149_I1.0580.88
455_Y502_I1.0580.88
656_E659_V1.0550.88
248_E307_N1.0530.88
549_V667_I1.0530.88
495_E498_R1.0520.88
548_V624_I1.0510.88
416_D421_S1.0510.88
11_D14_R1.0490.88
543_E598_T1.0480.88
623_E684_I1.0460.88
492_G496_A1.0420.87
291_I336_F1.0420.87
45_F49_F1.0410.87
78_V112_A1.0350.87
403_E411_K1.0350.87
604_S614_S1.0330.87
454_A530_A1.0320.87
580_E583_L1.0310.87
11_D15_K1.0310.87
193_L305_E1.0300.87
427_L535_D1.0300.87
431_K458_L1.0290.87
620_Y677_K1.0260.86
617_V691_L1.0230.86
416_D422_L1.0220.86
547_Y674_R1.0220.86
349_N353_N1.0210.86
363_N488_E1.0190.86
597_I650_V1.0180.86
173_A528_V1.0150.86
455_Y585_S1.0120.86
451_V493_I1.0110.86
314_A317_E1.0100.86
385_L390_L1.0100.86
125_N165_N1.0060.85
454_A529_M1.0060.85
65_D109_S1.0050.85
278_I290_V1.0050.85
679_T688_D1.0030.85
594_E657_W1.0020.85
378_E687_I1.0000.85
693_N697_N0.9980.85
240_T314_A0.9980.85
536_K593_N0.9960.85
193_L308_V0.9960.85
657_W661_K0.9940.85
24_T344_V0.9940.85
262_V334_I0.9920.85
211_F224_A0.9910.85
626_T639_N0.9900.84
591_S596_K0.9900.84
563_L635_N0.9880.84
140_A144_A0.9880.84
303_V311_V0.9860.84
89_A168_P0.9860.84
384_V610_A0.9830.84
462_G534_Q0.9830.84
280_L285_M0.9820.84
155_G431_K0.9820.84
549_V650_V0.9810.84
246_K310_E0.9810.84
362_K480_A0.9740.83
471_H493_I0.9730.83
422_L426_K0.9710.83
371_K374_D0.9710.83
45_F483_Y0.9690.83
276_E340_G0.9690.83
542_V651_L0.9680.83
194_K262_V0.9670.83
557_E575_K0.9660.83
549_V652_T0.9650.83
135_L396_A0.9620.83
136_K705_V0.9600.83
104_I151_V0.9580.82
671_I674_R0.9580.82
444_Y491_R0.9570.82
541_R620_Y0.9540.82
456_R581_D0.9510.82
57_I76_A0.9500.82
267_N349_N0.9460.82
143_A172_V0.9450.82
316_E322_C0.9440.82
459_A592_I0.9430.81
203_V282_V0.9420.81
12_E15_K0.9390.81
59_G63_W0.9390.81
346_L352_L0.9350.81
313_E317_E0.9330.81
243_I314_A0.9320.81
190_K193_L0.9280.80
301_Y311_V0.9280.80
453_E614_S0.9270.80
104_I117_L0.9250.80
65_D251_K0.9210.80
118_M155_G0.9210.80
499_F579_Q0.9180.80
188_V192_G0.9160.80
546_L550_S0.9130.79
134_L168_P0.9120.79
439_C446_C0.9120.79
557_E574_P0.9110.79
76_A183_I0.9100.79
407_S423_P0.9100.79
382_Y386_T0.9060.79
589_I593_N0.9040.79
373_V376_P0.9030.79
56_V468_A0.9000.78
112_A175_I0.8980.78
5_L13_I0.8970.78
288_S292_I0.8970.78
124_G165_N0.8960.78
588_V592_I0.8960.78
608_L649_I0.8920.78
77_V532_L0.8910.78
93_F228_A0.8910.78
622_V673_G0.8900.78
457_N614_S0.8900.78
442_D488_E0.8870.77
697_N700_N0.8870.77
490_I528_V0.8810.77
58_M183_I0.8800.77
551_V587_V0.8790.77
60_I63_W0.8780.77
538_L592_I0.8770.76
429_A533_V0.8750.76
616_L651_L0.8730.76
693_N696_D0.8730.76
656_E660_E0.8730.76
193_L328_I0.8710.76
443_G482_V0.8690.76
416_D602_D0.8680.76
453_E457_N0.8670.76
541_R651_L0.8660.76
548_V672_I0.8640.75
197_L253_L0.8630.75
125_N565_K0.8620.75
427_L533_V0.8620.75
470_D526_L0.8590.75
391_V702_L0.8570.75
267_N332_P0.8570.75
636_V685_D0.8550.75
115_I428_L0.8550.75
596_K661_K0.8510.74
3_I26_W0.8510.74
73_D179_R0.8500.74
275_I338_Y0.8500.74
459_A585_S0.8500.74
41_S483_Y0.8470.74
192_G248_E0.8460.74
415_A461_V0.8460.74
473_Q477_P0.8440.74
211_F483_Y0.8430.74
198_A315_F0.8430.74
75_W177_I0.8400.73
562_L565_K0.8400.73
544_D620_Y0.8390.73
457_N601_K0.8390.73
457_N604_S0.8390.73
153_V418_A0.8380.73
384_V609_A0.8380.73
240_T317_E0.8370.73
63_W184_K0.8370.73
548_V612_L0.8360.73
402_Y412_P0.8340.73
131_N165_N0.8330.73
243_I301_Y0.8310.73
10_M14_R0.8300.72
57_I468_A0.8290.72
587_V591_S0.8290.72
120_M157_E0.8270.72
242_E317_E0.8260.72
659_V671_I0.8240.72
310_E314_A0.8220.72
126_L135_L0.8210.72
274_D339_I0.8210.72
679_T692_K0.8190.71
679_T691_L0.8190.71
559_G573_A0.8150.71
268_G349_N0.8150.71
194_K273_V0.8140.71
580_E594_E0.8140.71
610_A613_F0.8140.71
594_E661_K0.8140.71
453_E601_K0.8120.71
546_L599_F0.8120.71
601_K604_S0.8120.71
483_Y487_V0.8100.71
458_L530_A0.8070.70
190_K330_N0.8070.70
381_I687_I0.8070.70
305_E327_E0.8070.70
198_A262_V0.8030.70
402_Y411_K0.8030.70
545_N671_I0.8020.70
149_I174_A0.8010.70
260_V506_G0.8010.70
452_A456_R0.7950.69
364_T481_E0.7930.69
377_L381_I0.7920.69
26_W65_D0.7910.69
620_Y676_N0.7880.68
545_N653_N0.7850.68
587_V590_D0.7840.68
468_A504_I0.7840.68
133_W137_N0.7840.68
577_R580_E0.7830.68
431_K461_V0.7810.68
334_I346_L0.7800.68
586_E590_D0.7800.68
473_Q476_D0.7800.68
333_V347_P0.7790.68
374_D563_L0.7790.68
243_I310_E0.7770.67
50_S57_I0.7760.67
214_R221_E0.7730.67
163_T440_A0.7730.67
561_S574_P0.7720.67
590_D661_K0.7720.67
616_L619_G0.7720.67
221_E224_A0.7700.67
278_I325_I0.7690.67
602_D605_R0.7670.66
71_I77_V0.7650.66
555_R644_S0.7650.66
370_E571_S0.7650.66
392_S702_L0.7630.66
419_V429_A0.7610.66
416_D423_P0.7600.66
563_L567_F0.7600.66
588_V662_S0.7580.65
71_I428_L0.7580.65
330_N382_Y0.7570.65
175_I430_I0.7570.65
48_S498_R0.7570.65
374_D377_L0.7570.65
41_S359_W0.7570.65
581_D585_S0.7540.65
431_K529_M0.7530.65
349_N352_L0.7520.65
93_F143_A0.7500.65
545_N675_V0.7480.64
427_L537_L0.7480.64
482_V485_T0.7470.64
479_K482_V0.7470.64
579_Q590_D0.7450.64
173_A430_I0.7440.64
444_Y447_G0.7430.64
486_F492_G0.7410.64
144_A148_S0.7410.64
90_I211_F0.7410.64
467_V502_I0.7400.64
228_A281_R0.7390.63
589_I592_I0.7380.63
445_E575_K0.7360.63
360_P480_A0.7360.63
659_V662_S0.7360.63
547_Y675_V0.7340.63
80_K172_V0.7340.63
548_V675_V0.7340.63
377_L641_F0.7330.63
482_V486_F0.7320.63
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255_G258_L0.7230.62
448_K575_K0.7210.62
115_I422_L0.7190.61
498_R550_S0.7190.61
397_Y698_Y0.7190.61
65_D80_K0.7180.61
381_I689_Y0.7180.61
43_K356_R0.7180.61
541_R545_N0.7160.61
542_V545_N0.7160.61
380_A384_V0.7150.61
125_N131_N0.7150.61
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688_D693_N0.7130.61
263_T334_I0.7120.61
192_G198_A0.7120.61
91_D94_N0.7120.61
194_K308_V0.7100.60
240_T243_I0.7100.60
380_A567_F0.7090.60
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302_A328_I0.7080.60
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315_F322_C0.7070.60
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698_Y701_F0.7040.60
132_V567_F0.7010.59
115_I177_I0.6980.59
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273_V325_I0.6980.59
546_L615_I0.6980.59
93_F230_P0.6970.59
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676_N682_L0.6950.59
546_L654_E0.6940.59
122_R157_E0.6930.59
253_L300_L0.6930.59
77_V175_I0.6920.58
159_S389_D0.6920.58
658_I661_K0.6910.58
245_D304_E0.6910.58
701_F705_V0.6880.58
50_S501_N0.6880.58
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658_I669_A0.6870.58
222_I282_V0.6860.58
625_S628_S0.6860.58
552_G556_K0.6860.58
402_Y408_T0.6850.58
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178_V183_I0.6820.57
433_D457_N0.6800.57
502_I529_M0.6800.57
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274_D338_Y0.6760.57
262_V273_V0.6750.57
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626_T672_I0.6750.57
542_V620_Y0.6750.57
623_E700_N0.6750.57
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281_R295_T0.6740.56
308_V312_C0.6720.56
691_L695_V0.6720.56
616_L683_T0.6700.56
407_S421_S0.6690.56
276_E287_P0.6690.56
471_H527_I0.6690.56
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538_L600_A0.6680.56
583_L597_I0.6670.56
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514_E520_P0.6660.56
553_Y668_V0.6650.55
542_V546_L0.6650.55
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486_F490_I0.6630.55
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536_K595_G0.6610.55
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31_A210_S0.6600.55
280_L338_Y0.6600.55
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448_K495_E0.6470.53
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215_K514_E0.6450.53
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291_I334_I0.6360.52
372_I375_L0.6350.52
549_V662_S0.6350.52
280_L283_K0.6340.52
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451_V527_I0.6330.52
68_A183_I0.6320.52
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201_T295_T0.6320.52
164_Y524_T0.6310.52
121_I142_I0.6300.51
194_K324_V0.6290.51
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454_A502_I0.6270.51
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266_T271_A0.6260.51
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550_S608_L0.6240.51
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330_N333_V0.6230.51
38_S41_S0.6230.51
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687_I694_I0.6220.51
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540_N618_H0.6210.50
48_S492_G0.6200.50
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543_E696_D0.6190.50
31_A207_G0.6190.50
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585_S647_R0.6180.50
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43_K47_K0.6130.50
333_V346_L0.6120.49
390_L453_E0.6120.49
551_V591_S0.6120.49
196_V312_C0.6110.49
469_V504_I0.6110.49
203_V288_S0.6100.49
593_N596_K0.6090.49
89_A515_N0.6090.49
685_D693_N0.6080.49
241_L245_D0.6080.49
412_P619_G0.6070.49
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31_A34_S0.6040.49
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551_V648_F0.5810.46
435_N438_M0.5810.46
662_S665_K0.5800.46
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496_A578_L0.5800.46
277_K323_S0.5780.46
612_L616_L0.5780.46
491_R495_E0.5780.46
10_M188_V0.5760.45
426_K534_Q0.5760.45
456_R616_L0.5750.45
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218_G516_N0.5750.45
338_Y343_L0.5750.45
551_V669_A0.5750.45
700_N703_E0.5740.45
233_G261_A0.5740.45
151_V405_N0.5730.45
622_V672_I0.5720.45
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540_N544_D0.5710.45
202_G299_M0.5700.45
419_V537_L0.5700.45
230_P552_G0.5700.45
49_F447_G0.5690.45
682_L690_N0.5690.45
57_I503_P0.5670.44
184_K250_I0.5670.44
564_S637_I0.5660.44
377_L640_L0.5660.44
583_L681_I0.5660.44
680_N690_N0.5660.44
469_V502_I0.5650.44
110_K186_S0.5650.44
416_D614_S0.5640.44
547_Y654_E0.5630.44
279_P322_C0.5620.44
9_E207_G0.5620.44
678_K690_N0.5610.44
390_L562_L0.5610.44
126_L702_L0.5600.44
188_V248_E0.5600.44
545_N674_R0.5600.44
217_S220_D0.5590.43
259_A311_V0.5590.43
52_D498_R0.5590.43
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540_N619_G0.5570.43
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364_T484_Y0.5570.43
465_G586_E0.5570.43
74_G181_D0.5560.43
195_L385_L0.5560.43
186_S249_A0.5560.43
209_A258_L0.5560.43
238_D400_F0.5560.43
373_V672_I0.5550.43
448_K576_V0.5550.43
75_W534_Q0.5540.43
242_E318_Y0.5540.43
146_G153_V0.5530.43
559_G574_P0.5530.43
24_T288_S0.5530.43
596_K655_P0.5510.43
161_D522_K0.5500.42
547_Y655_P0.5500.42
272_T342_D0.5500.42
206_L221_E0.5490.42
191_A194_K0.5490.42
674_R678_K0.5480.42
587_V669_A0.5470.42
409_V421_S0.5470.42
194_K198_A0.5470.42
16_R350_V0.5450.42
482_V492_G0.5440.42
375_L378_E0.5440.42
59_G196_V0.5440.42
295_T325_I0.5440.42
568_K637_I0.5430.42
197_L261_A0.5430.42
267_N348_T0.5420.42
597_I667_I0.5410.41
148_S400_F0.5410.41
558_L642_S0.5400.41
389_D565_K0.5400.41
555_R572_Q0.5400.41
378_E381_I0.5400.41
445_E576_V0.5390.41
41_S360_P0.5390.41
255_G511_F0.5390.41
616_L620_Y0.5390.41
476_D509_V0.5380.41
274_D287_P0.5380.41
23_E26_W0.5370.41
403_E412_P0.5370.41
598_T675_V0.5370.41
100_V145_Y0.5370.41
159_S387_H0.5360.41
312_C323_S0.5360.41
42_S83_S0.5360.41
598_T615_I0.5360.41
491_R498_R0.5360.41
245_D310_E0.5350.41
90_I104_I0.5350.41
77_V422_L0.5340.41
455_Y500_F0.5340.41
677_K680_N0.5330.41
583_L661_K0.5330.41
135_L158_L0.5330.41
72_G534_Q0.5330.41
72_G690_N0.5330.41
483_Y497_T0.5320.40
89_A118_M0.5320.40
601_K615_I0.5320.40
378_E688_D0.5320.40
260_V505_V0.5320.40
160_F492_G0.5320.40
28_V351_L0.5320.40
50_S56_V0.5310.40
420_V428_L0.5310.40
568_K571_S0.5310.40
583_L672_I0.5300.40
14_R20_E0.5300.40
203_V292_I0.5300.40
41_S89_A0.5300.40
157_E432_A0.5300.40
448_K499_F0.5300.40
660_E674_R0.5280.40
440_A522_K0.5280.40
600_A650_V0.5270.40
550_S649_I0.5260.40
79_I469_V0.5250.40
43_K511_F0.5250.40
516_N519_R0.5250.40
639_N697_N0.5250.40
49_F490_I0.5250.40
116_A430_I0.5240.40
191_A269_L0.5230.39
108_I265_I0.5230.39
305_E555_R0.5220.39
627_K685_D0.5220.39
668_V671_I0.5220.39
485_T497_T0.5210.39
258_L278_I0.5210.39
556_K638_E0.5210.39
196_V324_V0.5210.39
171_D509_V0.5210.39
195_L308_V0.5210.39
78_V178_V0.5200.39
615_I619_G0.5190.39
40_K80_K0.5180.39
499_F502_I0.5170.39
210_S214_R0.5170.39
28_V353_N0.5170.39
143_A148_S0.5170.39
543_E623_E0.5170.39
207_G288_S0.5160.39
192_G328_I0.5160.39
221_E391_V0.5150.39
30_D38_S0.5150.39
665_K674_R0.5150.39
89_A483_Y0.5150.39
459_A597_I0.5150.39
171_D473_Q0.5140.39
417_S536_K0.5140.39
386_T590_D0.5140.39
104_I237_L0.5140.39
403_E406_T0.5140.39
90_I513_N0.5140.39
369_E572_Q0.5140.39
194_K306_K0.5130.38
560_G574_P0.5130.38
593_N654_E0.5130.38
363_N484_Y0.5120.38
541_R544_D0.5120.38
592_I600_A0.5120.38
376_P610_A0.5110.38
70_D468_A0.5110.38
674_R684_I0.5110.38
481_E484_Y0.5110.38
49_F53_S0.5110.38
499_F582_L0.5110.38
587_V597_I0.5110.38
196_V262_V0.5100.38
550_S647_R0.5100.38
584_S646_G0.5100.38
113_K241_L0.5090.38
259_A334_I0.5080.38
463_A589_I0.5080.38
230_P447_G0.5070.38
462_G592_I0.5060.38
134_L617_V0.5060.38
417_S460_T0.5050.38
564_S635_N0.5050.38
188_V249_A0.5040.37
585_S646_G0.5040.37
48_S54_P0.5030.37
23_E286_N0.5030.37
375_L563_L0.5030.37
584_S648_F0.5020.37
149_I172_V0.5020.37
623_E685_D0.5010.37
262_V266_T0.5010.37
286_N441_E0.5010.37
596_K658_I0.5010.37
159_S605_R0.5000.37
479_K484_Y0.5000.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3viuA 1 0.9577 100 0.356 Contact Map
4lgyA 1 0.9732 100 0.362 Contact Map
1vk3A 1 0.8166 100 0.455 Contact Map
2zodA 2 0.4034 100 0.849 Contact Map
3u0oA 2 0.4161 100 0.856 Contact Map
2rb9A 2 0.4175 100 0.86 Contact Map
3vtiC 2 0.4048 100 0.865 Contact Map
3fd5A 2 0.4443 100 0.865 Contact Map
3wjpA 2 0.4386 100 0.868 Contact Map
2yxzA 2 0.4048 100 0.868 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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