VATA - SULSO - GREMLIN Contacts

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VATA - V-type ATP synthase alpha chain

UniProt:	Q9UWW6	Sequences: MDNGRIVRINGPLVVADNMRNAQMYEVVEVGEPRLIGEITRIEGDRAFIQVYEDTSGIKPNEPVYRTGAPLSIELGPGLIGKIFDGLQRPLDSIKELTKSPFIARGIKVPSIDRKTKWHFVPKVKKGDKVEGGSIIGIVNETPLVEHRILVPPYVHGTLKEVVAEGDYTVEDPIAIVDMNGDEVPVKLMQKWPVRIPRPFKEKLEPTEPLLTGTRVLDTIFPIAKGGTAAIPGPFGSGKTVTLQSLAKWSAAKIVIYVGCGERGNEMTDELRQFPSLKDPWTGRPLLERTILVANTSNMPVAAREASIYVGITMAEYFRDQGYDTLLVADSTSRWAEALRDLGGRMEEMPAEEGFPSYLPSRLAEYYERAGRVKTIGNPERFGSVTVASAVSPPGGDFTEPVTSQTLRFVKVFWPLDVSLAQARHYPAINWLQGFSAYVDLVANWWNTNVDPKWREMRDMMVRTLIREDELRQIVRLVGPESLAEKDKLILETARLIKEAFLKQNAYDDIDAFSSPQKQARIMRLIYLFNTYASKLVERGIPTKKIVDSMGQLLPEIIRSKAAIKNDELNRYDELERKLITVFENLEKEAGT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	592 (575)
Sequences:	989 (524)
Seq/√Len:	21.8

HALSA - VATA
SULSO - VATA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
119_H	167_D	6.783	1.00
460_M	531_T	6.076	1.00
124_V	159_L	5.263	1.00
417_D	430_N	4.697	1.00
556_E	578_K	4.658	1.00
117_K	169_T	4.472	1.00
234_P	237_S	4.355	1.00
119_H	165_E	4.196	1.00
461_M	523_M	3.936	1.00
179_M	182_D	3.876	1.00
161_E	176_I	3.826	1.00
129_K	158_T	3.793	1.00
122_P	165_E	3.669	1.00
74_E	114_R	3.610	1.00
220_I	461_M	3.609	1.00
125_K	128_D	3.583	1.00
169_T	172_D	3.511	1.00
284_R	288_E	3.461	1.00
176_I	183_E	3.407	1.00
202_E	374_K	3.372	1.00
121_V	140_N	3.317	1.00
176_I	185_P	3.317	1.00
223_I	386_T	3.246	1.00
34_R	65_Y	3.172	1.00
150_L	190_Q	3.161	1.00
143_P	284_R	3.073	1.00
178_D	184_V	3.031	1.00
451_D	520_A	3.001	0.99
160_K	178_D	2.955	0.99
568_E	571_R	2.872	0.99
308_I	339_L	2.820	0.99
377_G	381_R	2.755	0.99
138_I	146_E	2.729	0.99
22_A	39_I	2.714	0.99
159_L	162_V	2.692	0.99
160_K	183_E	2.685	0.99
13_L	48_F	2.642	0.99
158_T	178_D	2.631	0.99
144_L	282_T	2.583	0.98
121_V	138_I	2.463	0.98
372_R	382_F	2.431	0.98
173_P	187_K	2.413	0.97
114_R	171_E	2.397	0.97
80_I	145_V	2.351	0.97
136_I	175_A	2.351	0.97
117_K	167_D	2.350	0.97
84_F	170_V	2.349	0.97
132_G	153_P	2.332	0.97
256_I	314_M	2.324	0.97
291_I	314_M	2.303	0.97
136_I	151_V	2.252	0.96
442_V	446_W	2.251	0.96
464_T	490_I	2.245	0.96
445_W	449_N	2.237	0.96
136_I	174_I	2.226	0.96
579_L	583_F	2.219	0.96
178_D	182_D	2.206	0.96
171_E	189_M	2.200	0.96
150_L	321_Q	2.146	0.95
164_A	168_Y	2.114	0.94
200_F	373_V	2.102	0.94
457_M	524_R	2.084	0.94
16_A	64_V	2.071	0.94
136_I	186_V	2.048	0.93
93_S	96_E	2.044	0.93
130_V	151_V	2.041	0.93
84_F	111_S	2.040	0.93
112_I	170_V	2.021	0.93
117_K	172_D	2.018	0.93
160_K	176_I	1.976	0.92
81_G	288_E	1.952	0.92
155_V	177_V	1.936	0.91
564_I	572_Y	1.928	0.91
565_K	568_E	1.922	0.91
569_L	573_D	1.899	0.91
173_P	185_P	1.881	0.90
84_F	88_Q	1.879	0.90
564_I	569_L	1.872	0.90
145_V	254_I	1.870	0.90
493_T	530_N	1.868	0.90
528_L	580_I	1.857	0.90
293_V	314_M	1.847	0.89
159_L	175_A	1.843	0.89
17_D	46_R	1.834	0.89
273_Q	276_S	1.833	0.89
134_S	381_R	1.828	0.89
102_F	298_N	1.827	0.89
121_V	165_E	1.818	0.89
26_E	66_R	1.812	0.88
521_R	573_D	1.804	0.88
179_M	184_V	1.796	0.88
9_I	59_K	1.785	0.88
207_T	372_R	1.782	0.87
312_I	387_V	1.773	0.87
468_E	498_K	1.756	0.87
315_A	385_V	1.743	0.86
446_W	516_P	1.740	0.86
256_I	315_A	1.738	0.86
453_K	520_A	1.735	0.86
173_P	176_I	1.733	0.86
467_R	470_E	1.732	0.86
398_F	403_T	1.728	0.86
525_L	560_S	1.719	0.85
151_V	177_V	1.705	0.85
79_L	291_I	1.696	0.85
204_L	374_K	1.693	0.85
214_T	245_S	1.675	0.84
123_K	148_R	1.668	0.84
33_P	105_R	1.664	0.84
130_V	136_I	1.650	0.83
42_I	47_A	1.642	0.83
134_S	378_N	1.642	0.83
522_I	560_S	1.626	0.82
171_E	187_K	1.621	0.82
231_I	242_T	1.619	0.82
461_M	497_I	1.609	0.81
6_I	62_E	1.609	0.81
134_S	377_G	1.603	0.81
120_F	162_V	1.594	0.81
16_A	49_I	1.594	0.81
453_K	524_R	1.586	0.80
447_N	451_D	1.578	0.80
120_F	137_G	1.573	0.80
574_E	578_K	1.571	0.80
8_R	15_V	1.569	0.80
575_L	579_L	1.568	0.80
162_V	175_A	1.568	0.80
258_V	311_G	1.562	0.79
532_Y	580_I	1.559	0.79
32_E	63_P	1.540	0.78
219_T	519_Q	1.539	0.78
178_D	181_G	1.530	0.78
76_G	430_N	1.470	0.75
135_I	159_L	1.466	0.75
84_F	386_T	1.463	0.75
94_I	109_V	1.462	0.75
42_I	103_I	1.460	0.74
69_A	191_K	1.451	0.74
529_F	546_I	1.443	0.74
132_G	154_Y	1.426	0.73
174_I	188_L	1.426	0.73
269_D	273_Q	1.423	0.73
454_W	508_D	1.420	0.72
577_R	581_T	1.419	0.72
175_A	186_V	1.405	0.72
130_V	159_L	1.403	0.71
336_A	402_V	1.399	0.71
351_A	437_A	1.397	0.71
13_L	342_L	1.391	0.71
34_R	108_K	1.389	0.71
130_V	186_V	1.387	0.71
489_L	533_A	1.385	0.70
111_S	170_V	1.383	0.70
76_G	189_M	1.381	0.70
220_I	462_V	1.380	0.70
173_P	177_V	1.378	0.70
151_V	186_V	1.377	0.70
123_K	138_I	1.373	0.70
168_Y	174_I	1.366	0.69
220_I	523_M	1.362	0.69
324_D	384_S	1.353	0.69
471_L	475_V	1.345	0.68
366_Y	389_S	1.343	0.68
571_R	574_E	1.336	0.68
532_Y	535_K	1.334	0.67
245_S	512_A	1.331	0.67
492_E	495_R	1.325	0.67
140_N	146_E	1.323	0.67
269_D	388_A	1.316	0.66
170_V	189_M	1.312	0.66
564_I	568_E	1.309	0.66
76_G	188_L	1.308	0.66
464_T	494_A	1.305	0.66
234_P	418_V	1.299	0.65
48_F	484_A	1.298	0.65
474_I	485_E	1.295	0.65
94_I	104_A	1.292	0.65
204_L	372_R	1.263	0.63
135_I	146_E	1.260	0.63
114_R	189_M	1.242	0.62
425_H	431_W	1.234	0.61
520_A	524_R	1.218	0.60
84_F	339_L	1.217	0.60
93_S	113_D	1.200	0.59
84_F	109_V	1.197	0.59
162_V	174_I	1.196	0.59
225_K	251_A	1.189	0.58
225_K	324_D	1.186	0.58
208_E	372_R	1.185	0.58
24_M	246_L	1.174	0.57
485_E	488_K	1.169	0.57
553_L	582_V	1.166	0.57
125_K	524_R	1.163	0.57
400_E	403_T	1.162	0.57
123_K	146_E	1.160	0.56
136_I	149_I	1.159	0.56
555_P	558_I	1.157	0.56
282_T	285_P	1.151	0.56
288_E	495_R	1.135	0.55
349_M	475_V	1.133	0.55
439_V	458_R	1.132	0.55
14_V	188_L	1.132	0.55
275_P	478_V	1.131	0.54
44_G	194_V	1.131	0.54
122_P	137_G	1.123	0.54
443_A	447_N	1.123	0.54
92_D	96_E	1.120	0.54
9_I	410_V	1.115	0.53
74_E	110_P	1.111	0.53
347_E	404_S	1.108	0.53
314_M	327_L	1.096	0.52
447_N	570_N	1.085	0.51
355_F	473_Q	1.084	0.51
5_R	17_D	1.082	0.51
79_L	314_M	1.080	0.51
6_I	9_I	1.071	0.50
486_K	538_E	1.068	0.50
409_F	426_Y	1.063	0.50
139_V	149_I	1.063	0.50
460_M	527_Y	1.062	0.50
467_R	508_D	1.059	0.50
530_N	534_S	1.054	0.49
172_D	187_K	1.052	0.49
177_V	183_E	1.052	0.49
130_V	177_V	1.050	0.49
258_V	327_L	1.046	0.49
351_A	409_F	1.041	0.48
187_K	190_Q	1.036	0.48
113_D	116_T	1.036	0.48
30_V	49_I	1.032	0.48
112_I	188_L	1.030	0.48
124_V	128_D	1.030	0.48
572_Y	579_L	1.026	0.47
508_D	512_A	1.025	0.47
223_I	423_A	1.024	0.47
493_T	529_F	1.020	0.47
17_D	45_D	1.016	0.47
251_A	255_V	1.006	0.46
161_E	164_A	1.000	0.46
126_K	161_E	0.999	0.46
332_T	389_S	0.997	0.45
443_A	454_W	0.995	0.45
178_D	183_E	0.994	0.45
73_I	310_V	0.990	0.45
216_V	428_A	0.989	0.45
527_Y	531_T	0.987	0.45
76_G	112_I	0.983	0.44
185_P	509_D	0.980	0.44
103_I	107_I	0.975	0.44
258_V	352_E	0.974	0.44
99_K	104_A	0.971	0.44
42_I	430_N	0.970	0.44
147_H	317_Y	0.969	0.44
457_M	527_Y	0.967	0.43
29_E	108_K	0.967	0.43
230_A	410_V	0.963	0.43
241_V	407_L	0.962	0.43
480_P	488_K	0.961	0.43
188_L	388_A	0.961	0.43
135_I	148_R	0.956	0.43
573_D	577_R	0.955	0.43
252_A	255_V	0.948	0.42
161_E	173_P	0.947	0.42
76_G	220_I	0.943	0.42
94_I	103_I	0.941	0.42
353_E	424_R	0.939	0.42
217_L	242_T	0.939	0.42
245_S	321_Q	0.937	0.41
349_M	471_L	0.932	0.41
473_Q	498_K	0.923	0.40
275_P	396_G	0.923	0.40
286_L	352_E	0.923	0.40
496_L	554_L	0.921	0.40
95_K	101_P	0.920	0.40
549_S	582_V	0.918	0.40
242_T	506_A	0.916	0.40
529_F	554_L	0.913	0.40
549_S	553_L	0.909	0.40
197_P	490_I	0.907	0.39
150_L	497_I	0.906	0.39
298_N	572_Y	0.903	0.39
279_D	400_E	0.902	0.39
410_V	415_P	0.900	0.39
167_D	535_K	0.898	0.39
15_V	46_R	0.897	0.39
234_P	243_L	0.896	0.39
457_M	520_A	0.894	0.39
9_I	14_V	0.893	0.39
324_D	360_P	0.891	0.38
138_I	148_R	0.891	0.38
6_I	176_I	0.890	0.38
535_K	570_N	0.890	0.38
357_S	368_E	0.889	0.38
265_N	298_N	0.887	0.38
74_E	79_L	0.887	0.38
100_S	404_S	0.885	0.38
546_I	583_F	0.883	0.38
243_L	388_A	0.883	0.38
451_D	524_R	0.881	0.38
243_L	326_L	0.880	0.38
3_N	65_Y	0.880	0.38
273_Q	507_Y	0.876	0.37
219_T	501_F	0.875	0.37
270_E	326_L	0.872	0.37
365_E	386_T	0.867	0.37
224_A	442_V	0.859	0.36
360_P	409_F	0.858	0.36
579_L	582_V	0.857	0.36
483_L	518_K	0.857	0.36
264_G	337_E	0.857	0.36
253_K	442_V	0.857	0.36
100_S	366_Y	0.856	0.36
120_F	188_L	0.854	0.36
385_V	448_T	0.853	0.36
433_Q	572_Y	0.846	0.36
523_M	572_Y	0.846	0.36
19_M	47_A	0.846	0.36
40_T	328_V	0.843	0.35
81_G	508_D	0.841	0.35
529_F	557_I	0.840	0.35
444_N	448_T	0.840	0.35
243_L	328_V	0.840	0.35
407_L	487_D	0.835	0.35
290_T	310_V	0.834	0.35
88_Q	170_V	0.834	0.35
378_N	381_R	0.834	0.35
298_N	558_I	0.834	0.35
102_F	318_F	0.833	0.35
9_I	58_I	0.833	0.35
10_N	16_A	0.832	0.35
138_I	379_P	0.832	0.35
309_Y	339_L	0.831	0.35
126_K	160_K	0.828	0.34
243_L	404_S	0.828	0.34
80_I	254_I	0.827	0.34
422_Q	426_Y	0.827	0.34
102_F	228_T	0.826	0.34
415_P	484_A	0.824	0.34
243_L	413_F	0.823	0.34
497_I	523_M	0.821	0.34
374_K	382_F	0.820	0.34
26_E	344_G	0.819	0.34
49_I	302_A	0.817	0.34
179_M	183_E	0.817	0.34
378_N	388_A	0.816	0.34
40_T	343_G	0.816	0.34
464_T	527_Y	0.816	0.34
471_L	492_E	0.815	0.34
140_N	164_A	0.814	0.34
131_E	201_K	0.814	0.34
188_L	378_N	0.813	0.34
418_V	437_A	0.813	0.34
153_P	199_P	0.812	0.33
149_I	175_A	0.810	0.33
87_L	326_L	0.809	0.33
246_L	388_A	0.809	0.33
386_T	422_Q	0.809	0.33
58_I	339_L	0.804	0.33
14_V	42_I	0.804	0.33
124_V	130_V	0.803	0.33
74_E	191_K	0.799	0.33
481_E	507_Y	0.799	0.33
553_L	576_E	0.797	0.33
216_V	387_V	0.796	0.33
123_K	452_P	0.793	0.32
451_D	456_E	0.793	0.32
23_Q	42_I	0.792	0.32
377_G	380_E	0.792	0.32
468_E	473_Q	0.791	0.32
192_W	198_R	0.789	0.32
186_V	444_N	0.789	0.32
385_V	422_Q	0.789	0.32
489_L	537_V	0.789	0.32
280_P	286_L	0.788	0.32
578_K	582_V	0.787	0.32
131_E	156_H	0.786	0.32
258_V	268_T	0.786	0.32
177_V	186_V	0.785	0.32
112_I	561_K	0.779	0.32
124_V	175_A	0.778	0.31
431_W	498_K	0.778	0.31
581_T	584_E	0.777	0.31
41_R	48_F	0.775	0.31
84_F	150_L	0.774	0.31
420_L	431_W	0.773	0.31
521_R	572_Y	0.772	0.31
102_F	546_I	0.772	0.31
344_G	358_Y	0.768	0.31
237_S	258_V	0.767	0.31
208_E	225_K	0.767	0.31
576_E	579_L	0.767	0.31
362_R	468_E	0.766	0.31
491_L	523_M	0.766	0.31
272_R	288_E	0.765	0.31
139_V	269_D	0.764	0.31
524_R	527_Y	0.764	0.31
19_M	22_A	0.763	0.31
123_K	159_L	0.761	0.30
93_S	97_L	0.759	0.30
4_G	19_M	0.757	0.30
155_V	184_V	0.757	0.30
339_L	365_E	0.757	0.30
41_R	245_S	0.756	0.30
45_D	373_V	0.755	0.30
140_N	149_I	0.754	0.30
223_I	229_A	0.754	0.30
396_G	432_L	0.753	0.30
521_R	569_L	0.752	0.30
19_M	364_A	0.752	0.30
473_Q	522_I	0.752	0.30
459_D	463_R	0.752	0.30
452_P	574_E	0.746	0.30
84_F	445_W	0.745	0.30
420_L	425_H	0.744	0.30
268_T	347_E	0.742	0.29
389_S	406_T	0.739	0.29
8_R	41_R	0.738	0.29
83_I	542_P	0.737	0.29
250_S	433_Q	0.735	0.29
374_K	584_E	0.734	0.29
143_P	288_E	0.729	0.29
94_I	107_I	0.729	0.29
386_T	523_M	0.729	0.29
528_L	531_T	0.728	0.29
394_P	499_E	0.727	0.29
42_I	385_V	0.727	0.29
237_S	418_V	0.727	0.29
259_G	397_D	0.727	0.29
14_V	417_D	0.725	0.28
9_I	372_R	0.724	0.28
159_L	177_V	0.724	0.28
405_Q	409_F	0.721	0.28
41_R	411_K	0.721	0.28
276_S	507_Y	0.720	0.28
446_W	455_R	0.720	0.28
246_L	256_I	0.720	0.28
496_L	526_I	0.719	0.28
275_P	287_L	0.718	0.28
245_S	249_W	0.716	0.28
528_L	576_E	0.716	0.28
153_P	415_P	0.715	0.28
115_K	169_T	0.712	0.28
161_E	183_E	0.712	0.28
552_Q	582_V	0.709	0.28
20_R	386_T	0.709	0.28
287_L	415_P	0.708	0.28
45_D	210_L	0.708	0.28
250_S	517_Q	0.707	0.27
145_V	318_F	0.706	0.27
116_T	129_K	0.705	0.27
508_D	562_A	0.701	0.27
6_I	58_I	0.701	0.27
243_L	519_Q	0.701	0.27
570_N	574_E	0.698	0.27
161_E	168_Y	0.697	0.27
39_I	312_I	0.697	0.27
139_V	396_G	0.696	0.27
347_E	481_E	0.696	0.27
282_T	493_T	0.694	0.27
123_K	136_I	0.693	0.27
302_A	347_E	0.692	0.27
439_V	443_A	0.692	0.27
321_Q	347_E	0.692	0.27
231_I	557_I	0.691	0.27
419_S	422_Q	0.690	0.27
415_P	433_Q	0.689	0.27
60_P	527_Y	0.689	0.27
5_R	93_S	0.688	0.26
42_I	46_R	0.687	0.26
352_E	424_R	0.687	0.26
269_D	514_S	0.685	0.26
245_S	506_A	0.684	0.26
287_L	396_G	0.684	0.26
399_T	435_F	0.683	0.26
274_F	346_M	0.682	0.26
100_S	271_L	0.681	0.26
575_L	582_V	0.681	0.26
405_Q	487_D	0.680	0.26
116_T	567_D	0.680	0.26
537_V	544_K	0.679	0.26
114_R	170_V	0.679	0.26
201_K	456_E	0.678	0.26
126_K	497_I	0.674	0.26
279_D	424_R	0.674	0.26
103_I	250_S	0.674	0.26
420_L	483_L	0.673	0.26
237_S	403_T	0.673	0.26
447_N	455_R	0.673	0.26
195_R	427_P	0.673	0.26
268_T	326_L	0.670	0.26
280_P	353_E	0.670	0.26
16_A	19_M	0.670	0.26
446_W	490_I	0.670	0.26
250_S	324_D	0.669	0.25
259_G	267_M	0.669	0.25
39_I	269_D	0.667	0.25
96_E	202_E	0.667	0.25
26_E	269_D	0.667	0.25
114_R	269_D	0.666	0.25
524_R	576_E	0.665	0.25
380_E	579_L	0.665	0.25
249_W	512_A	0.664	0.25
252_A	328_V	0.664	0.25
134_S	188_L	0.663	0.25
88_Q	111_S	0.663	0.25
94_I	421_A	0.663	0.25
146_E	253_K	0.662	0.25
576_E	580_I	0.662	0.25
445_W	546_I	0.661	0.25
84_F	529_F	0.659	0.25
241_V	437_A	0.659	0.25
328_V	522_I	0.658	0.25
423_A	426_Y	0.658	0.25
485_E	541_I	0.656	0.25
159_L	535_K	0.656	0.25
426_Y	566_N	0.656	0.25
100_S	280_P	0.655	0.25
564_I	573_D	0.655	0.25
81_G	291_I	0.654	0.25
445_W	450_V	0.654	0.25
450_V	520_A	0.654	0.25
177_V	486_K	0.654	0.25
231_I	472_R	0.653	0.25
377_G	487_D	0.653	0.25
151_V	159_L	0.653	0.25
251_A	281_W	0.652	0.25
252_A	458_R	0.652	0.25
27_V	514_S	0.652	0.25
228_T	298_N	0.651	0.25
124_V	162_V	0.650	0.25
84_F	527_Y	0.650	0.25
352_E	542_P	0.650	0.25
351_A	418_V	0.649	0.24
431_W	468_E	0.649	0.24
279_D	353_E	0.649	0.24
187_K	205_E	0.648	0.24
321_Q	498_K	0.648	0.24
210_L	458_R	0.646	0.24
39_I	324_D	0.645	0.24
339_L	351_A	0.644	0.24
358_Y	362_R	0.644	0.24
96_E	172_D	0.642	0.24
580_I	584_E	0.642	0.24
405_Q	446_W	0.639	0.24
25_Y	29_E	0.639	0.24
531_T	535_K	0.639	0.24
231_I	583_F	0.638	0.24
160_K	177_V	0.637	0.24
142_T	145_V	0.637	0.24
206_P	224_A	0.637	0.24
456_E	567_D	0.636	0.24
208_E	386_T	0.636	0.24
103_I	285_P	0.636	0.24
453_K	457_M	0.634	0.24
120_F	149_I	0.634	0.24
237_S	243_L	0.634	0.24
87_L	292_L	0.632	0.24
26_E	168_Y	0.631	0.24
327_L	339_L	0.630	0.24
229_A	498_K	0.630	0.24
455_R	459_D	0.630	0.24
128_D	159_L	0.630	0.24
21_N	42_I	0.629	0.23
267_M	294_A	0.629	0.23
257_Y	267_M	0.628	0.23
264_G	397_D	0.628	0.23
407_L	426_Y	0.628	0.23
365_E	559_R	0.626	0.23
411_K	418_V	0.626	0.23
206_P	365_E	0.625	0.23
69_A	428_A	0.625	0.23
177_V	577_R	0.625	0.23
385_V	507_Y	0.623	0.23
10_N	387_V	0.623	0.23
411_K	484_A	0.623	0.23
463_R	467_R	0.623	0.23
185_P	463_R	0.622	0.23
566_N	571_R	0.622	0.23
224_A	432_L	0.622	0.23
405_Q	484_A	0.621	0.23
552_Q	555_P	0.619	0.23
34_R	58_I	0.619	0.23
201_K	380_E	0.617	0.23
409_F	500_A	0.617	0.23
442_V	476_R	0.617	0.23
231_I	412_V	0.616	0.23
214_T	326_L	0.616	0.23
9_I	62_E	0.615	0.23
28_V	405_Q	0.614	0.23
160_K	188_L	0.611	0.23
74_E	478_V	0.611	0.23
126_K	323_Y	0.611	0.23
6_I	164_A	0.611	0.23
575_L	578_K	0.610	0.23
270_E	292_L	0.610	0.23
447_N	453_K	0.609	0.23
495_R	498_K	0.609	0.23
564_I	571_R	0.609	0.23
130_V	154_Y	0.609	0.23
254_I	570_N	0.606	0.22
11_G	483_L	0.606	0.22
115_K	125_K	0.605	0.22
432_L	519_Q	0.604	0.22
8_R	13_L	0.604	0.22
445_W	525_L	0.604	0.22
160_K	185_P	0.603	0.22
280_P	519_Q	0.602	0.22
230_A	253_K	0.602	0.22
24_M	417_D	0.602	0.22
454_W	480_P	0.601	0.22
7_V	17_D	0.600	0.22
47_A	269_D	0.600	0.22
234_P	409_F	0.600	0.22
241_V	487_D	0.600	0.22
324_D	372_R	0.598	0.22
254_I	323_Y	0.598	0.22
87_L	243_L	0.598	0.22
112_I	498_K	0.598	0.22
103_I	466_I	0.598	0.22
480_P	491_L	0.598	0.22
355_F	437_A	0.598	0.22
120_F	482_S	0.598	0.22
426_Y	500_A	0.598	0.22
237_S	428_A	0.596	0.22
318_F	579_L	0.595	0.22
119_H	168_Y	0.594	0.22
326_L	399_T	0.594	0.22
144_L	284_R	0.593	0.22
47_A	72_S	0.593	0.22
342_L	346_M	0.593	0.22
243_L	268_T	0.593	0.22
403_T	503_K	0.592	0.22
58_I	211_L	0.592	0.22
168_Y	188_L	0.592	0.22
332_T	406_T	0.591	0.22
268_T	292_L	0.589	0.22
3_N	63_P	0.588	0.22
148_R	570_N	0.588	0.22
265_N	435_F	0.588	0.22
478_V	536_L	0.588	0.22
100_S	549_S	0.587	0.21
279_D	519_Q	0.587	0.21
320_D	397_D	0.587	0.21
13_L	103_I	0.586	0.21
255_V	386_T	0.586	0.21
570_N	573_D	0.586	0.21
102_F	485_E	0.585	0.21
154_Y	184_V	0.584	0.21
554_L	558_I	0.583	0.21
216_V	231_I	0.583	0.21
361_S	424_R	0.582	0.21
355_F	485_E	0.581	0.21
351_A	404_S	0.580	0.21
365_E	385_V	0.579	0.21
320_D	483_L	0.579	0.21
574_E	577_R	0.579	0.21
575_L	583_F	0.578	0.21
259_G	294_A	0.576	0.21
257_Y	397_D	0.575	0.21
110_P	114_R	0.574	0.21
245_S	513_F	0.574	0.21
464_T	530_N	0.574	0.21
500_A	558_I	0.573	0.21
3_N	121_V	0.573	0.21
65_Y	121_V	0.573	0.21
242_T	400_E	0.573	0.21
111_S	384_S	0.572	0.21
40_T	522_I	0.571	0.21
508_D	519_Q	0.571	0.21
363_L	492_E	0.570	0.21
220_I	488_K	0.570	0.21
461_M	527_Y	0.570	0.21
73_I	292_L	0.570	0.21
230_A	385_V	0.570	0.21
126_K	164_A	0.570	0.21
71_L	194_V	0.569	0.21
265_N	337_E	0.569	0.21
237_S	352_E	0.568	0.21
16_A	25_Y	0.568	0.21
95_K	158_T	0.568	0.21
409_F	423_A	0.566	0.21
14_V	255_V	0.566	0.21
182_D	374_K	0.566	0.21
467_R	490_I	0.566	0.21
246_L	327_L	0.565	0.20
259_G	264_G	0.565	0.20
361_S	409_F	0.565	0.20
564_I	567_D	0.565	0.20
121_V	159_L	0.564	0.20
280_P	508_D	0.564	0.20
24_M	476_R	0.564	0.20
373_V	377_G	0.564	0.20
573_D	576_E	0.563	0.20
252_A	268_T	0.563	0.20
29_E	253_K	0.563	0.20
125_K	130_V	0.563	0.20
192_W	199_P	0.562	0.20
577_R	580_I	0.562	0.20
229_A	386_T	0.562	0.20
73_I	275_P	0.562	0.20
24_M	425_H	0.561	0.20
493_T	496_L	0.560	0.20
535_K	538_E	0.560	0.20
35_L	53_E	0.560	0.20
472_R	476_R	0.560	0.20
517_Q	568_E	0.559	0.20
228_T	503_K	0.559	0.20
26_E	418_V	0.557	0.20
237_S	242_T	0.557	0.20
242_T	385_V	0.557	0.20
453_K	456_E	0.556	0.20
271_L	362_R	0.556	0.20
492_E	508_D	0.556	0.20
79_L	419_S	0.555	0.20
337_E	354_G	0.555	0.20
327_L	387_V	0.555	0.20
439_V	455_R	0.554	0.20
41_R	398_F	0.554	0.20
68_G	191_K	0.554	0.20
156_H	180_N	0.554	0.20
399_T	522_I	0.554	0.20
254_I	400_E	0.554	0.20
100_S	286_L	0.553	0.20
309_Y	413_F	0.553	0.20
71_L	427_P	0.552	0.20
4_G	396_G	0.552	0.20
136_I	159_L	0.552	0.20
347_E	400_E	0.551	0.20
366_Y	425_H	0.549	0.20
234_P	508_D	0.549	0.20
230_A	409_F	0.549	0.20
237_S	484_A	0.549	0.20
506_A	531_T	0.549	0.20
432_L	494_A	0.548	0.20
249_W	437_A	0.548	0.20
337_E	397_D	0.548	0.20
403_T	485_E	0.547	0.20
265_N	294_A	0.547	0.20
230_A	415_P	0.547	0.20
257_Y	390_A	0.546	0.20
231_I	315_A	0.545	0.20
386_T	426_Y	0.545	0.20
570_N	584_E	0.544	0.20
347_E	438_Y	0.544	0.20
122_P	162_V	0.544	0.20
279_D	282_T	0.543	0.20
31_G	417_D	0.543	0.20
13_L	557_I	0.542	0.20
128_D	160_K	0.542	0.20
16_A	318_F	0.541	0.19
259_G	390_A	0.541	0.19
13_L	484_A	0.541	0.19
342_L	473_Q	0.540	0.19
312_I	412_V	0.539	0.19
104_A	112_I	0.539	0.19
48_F	342_L	0.539	0.19
67_T	496_L	0.539	0.19
460_M	464_T	0.538	0.19
237_S	246_L	0.538	0.19
514_S	562_A	0.537	0.19
101_P	462_V	0.536	0.19
126_K	553_L	0.536	0.19
115_K	172_D	0.536	0.19
339_L	385_V	0.536	0.19
189_M	314_M	0.535	0.19
569_L	579_L	0.534	0.19
404_S	437_A	0.534	0.19
349_M	358_Y	0.534	0.19
432_L	469_D	0.534	0.19
102_F	386_T	0.534	0.19
546_I	553_L	0.533	0.19
267_M	390_A	0.533	0.19
247_A	361_S	0.533	0.19
62_E	518_K	0.532	0.19
182_D	570_N	0.532	0.19
347_E	353_E	0.532	0.19
445_W	458_R	0.532	0.19
364_A	385_V	0.531	0.19
280_P	400_E	0.531	0.19
269_D	507_Y	0.530	0.19
105_R	470_E	0.529	0.19
406_T	410_V	0.527	0.19
221_F	325_T	0.527	0.19
306_A	310_V	0.527	0.19
431_W	473_Q	0.527	0.19
173_P	381_R	0.526	0.19
36_I	217_L	0.525	0.19
230_A	406_T	0.524	0.19
203_K	423_A	0.524	0.19
87_L	267_M	0.524	0.19
39_I	42_I	0.523	0.19
269_D	288_E	0.522	0.19
269_D	275_P	0.522	0.19
156_H	574_E	0.522	0.19
64_V	127_G	0.522	0.19
216_V	308_I	0.521	0.19
242_T	269_D	0.520	0.19
153_P	177_V	0.520	0.19
405_Q	500_A	0.520	0.19
255_V	327_L	0.520	0.19
258_V	270_E	0.519	0.19
54_D	229_A	0.519	0.19
224_A	461_M	0.519	0.19
243_L	347_E	0.519	0.19
237_S	424_R	0.518	0.19
254_I	405_Q	0.518	0.19
286_L	327_L	0.518	0.19
95_K	181_G	0.518	0.19
32_E	131_E	0.517	0.18
28_V	94_I	0.517	0.18
286_L	424_R	0.517	0.18
268_T	408_R	0.517	0.18
194_V	275_P	0.517	0.18
275_P	292_L	0.516	0.18
153_P	242_T	0.516	0.18
259_G	320_D	0.516	0.18
84_F	94_I	0.516	0.18
347_E	468_E	0.515	0.18
110_P	444_N	0.514	0.18
280_P	424_R	0.514	0.18
76_G	170_V	0.513	0.18
33_P	363_L	0.513	0.18
51_V	55_T	0.512	0.18
275_P	498_K	0.512	0.18
9_I	546_I	0.512	0.18
248_K	423_A	0.512	0.18
209_P	414_W	0.512	0.18
79_L	208_E	0.511	0.18
173_P	567_D	0.511	0.18
70_P	388_A	0.511	0.18
84_F	293_V	0.511	0.18
66_R	446_W	0.510	0.18
279_D	408_R	0.510	0.18
327_L	352_E	0.510	0.18
168_Y	423_A	0.510	0.18
320_D	414_W	0.510	0.18
174_I	283_G	0.509	0.18
37_G	292_L	0.509	0.18
269_D	385_V	0.509	0.18
22_A	377_G	0.508	0.18
227_G	438_Y	0.508	0.18
441_L	458_R	0.508	0.18
323_Y	431_W	0.508	0.18
480_P	503_K	0.508	0.18
34_R	173_P	0.507	0.18
400_E	424_R	0.506	0.18
267_M	337_E	0.506	0.18
412_V	478_V	0.504	0.18
26_E	276_S	0.504	0.18
170_V	188_L	0.504	0.18
36_I	314_M	0.503	0.18
264_G	354_G	0.503	0.18
145_V	255_V	0.503	0.18
570_N	577_R	0.503	0.18
541_I	545_K	0.503	0.18
459_D	581_T	0.503	0.18
243_L	279_D	0.502	0.18
425_H	483_L	0.502	0.18
200_F	442_V	0.501	0.18
288_E	484_A	0.500	0.18
498_K	523_M	0.500	0.18
220_I	385_V	0.500	0.18

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mfyA	1	0.8632	100	0.33	Contact Map
3vr4A	1	0.9899	100	0.339	Contact Map
3j9tA	1	0.9882	100	0.346	Contact Map
3gqbA	1	0.9747	100	0.355	Contact Map
3vr4D	1	0.7416	100	0.601	Contact Map
3j9tB	1	0.7331	100	0.609	Contact Map
3gqbB	1	0.7416	100	0.61	Contact Map
2c61A	2	0.7162	100	0.616	Contact Map
3oaaA	2	0.799	100	0.617	Contact Map
1fx0B	3	0.7534	100	0.619	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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