GLYA - SULSO - GREMLIN Contacts

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GLYA - Serine hydroxymethyltransferase

UniProt:	Q9UWT5	Sequences: MSLPKELEKVLEITKAQNVWRRTQTLNLIASENVMSPLAESVYMSDFMSRYAEGKPYKRYYQGTKYTDEIETLTMELMNEITNSKDCDLRPTSGTIANAAVFRVLAEPGDKALIAPVQAGAHVSHTKFGTLGALGIQHIEMPFDEENINVDVDKAIKMIEEVKPKFVVLGGSLYLFPHPTKELAQHVHAVGAKLVYDAAHVYGLIEGKVWSNPLKDGADIMTVSTHKTFPGPQGGAIFSDGSEVFKQVSKTIFPWFVSNHHLHRLPATAVTAIEMKYFGESYANQILRNSKALAEALAERGFKVIGENLGYTKSHQVAVDVRQFGGGNKIAKLLEDANIIVNKNLLPYDKPEDVSDPSGLRIGVQEMTRYGMKEGEMEEIAELFKKVIIDKKDVNEVKKEVIEMRRNFLEVKYTFDDMKDLEKYSSKSLKLII	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	433 (398)
Sequences:	4038 (1801)
Seq/√Len:	90.3

ECOLI - GLYA
BACSU - GLYA
HALSA - GLYA
SULSO - GLYA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
156_I	189_A	4.231	1.00
184_A	188_H	4.211	1.00
160_E	189_A	3.342	1.00
72_T	76_E	3.304	1.00
177_P	211_S	3.038	1.00
105_L	220_I	3.034	1.00
288_R	374_E	2.944	1.00
154_K	157_K	2.871	1.00
78_M	236_A	2.840	1.00
111_K	137_Q	2.822	1.00
148_I	303_K	2.776	1.00
223_V	236_A	2.745	1.00
17_Q	69_E	2.742	1.00
150_V	155_A	2.741	1.00
156_I	160_E	2.686	1.00
144_D	147_N	2.684	1.00
373_K	376_E	2.605	1.00
156_I	182_E	2.587	1.00
330_I	388_I	2.496	1.00
273_I	276_K	2.487	1.00
181_K	185_Q	2.415	1.00
157_K	161_E	2.403	1.00
26_L	367_M	2.400	1.00
295_E	299_E	2.342	1.00
284_N	288_R	2.334	1.00
158_M	162_V	2.300	1.00
285_Q	373_K	2.298	1.00
13_I	69_E	2.294	1.00
207_G	283_A	2.269	1.00
111_K	162_V	2.229	1.00
209_V	287_L	2.173	1.00
300_R	382_E	2.144	1.00
285_Q	374_E	2.088	1.00
72_T	75_M	2.082	1.00
300_R	385_K	2.075	1.00
196_Y	218_A	2.057	1.00
296_A	381_A	2.057	1.00
176_F	313_K	2.049	1.00
87_C	238_F	2.042	1.00
379_E	400_E	2.020	1.00
139_I	162_V	2.010	1.00
296_A	299_E	2.009	1.00
155_A	183_L	1.980	1.00
302_F	385_K	1.971	1.00
296_A	378_E	1.952	1.00
112_A	138_H	1.946	1.00
78_M	223_V	1.944	1.00
372_M	380_I	1.941	1.00
296_A	382_E	1.937	1.00
367_M	377_M	1.933	1.00
341_V	362_I	1.932	1.00
43_Y	264_R	1.914	1.00
13_I	70_I	1.906	1.00
106_A	166_F	1.879	1.00
86_D	239_S	1.864	1.00
86_D	249_S	1.822	1.00
175_L	304_V	1.798	1.00
76_E	80_E	1.758	1.00
239_S	245_F	1.751	1.00
154_K	158_M	1.733	1.00
325_G	352_E	1.727	1.00
17_Q	66_Y	1.724	1.00
201_V	210_W	1.717	1.00
111_K	139_I	1.701	1.00
390_D	393_D	1.695	1.00
387_V	397_V	1.657	1.00
183_L	194_L	1.651	1.00
386_K	400_E	1.635	1.00
66_Y	69_E	1.625	1.00
36_S	274_E	1.596	1.00
292_A	296_A	1.579	1.00
43_Y	267_A	1.570	1.00
10_V	70_I	1.569	1.00
86_D	245_F	1.567	1.00
169_L	183_L	1.566	1.00
285_Q	288_R	1.553	1.00
152_V	182_E	1.550	1.00
28_L	367_M	1.545	1.00
19_V	23_T	1.533	1.00
209_V	284_N	1.532	1.00
379_E	383_L	1.523	1.00
375_G	378_E	1.514	1.00
322_R	352_E	1.511	1.00
289_N	368_T	1.507	1.00
95_T	124_S	1.504	1.00
293_L	381_A	1.503	1.00
333_L	391_K	1.499	1.00
293_L	377_M	1.499	1.00
209_V	283_A	1.498	1.00
102_F	168_V	1.484	1.00
219_D	240_D	1.479	1.00
385_K	389_I	1.478	1.00
280_E	284_N	1.474	1.00
99_A	131_L	1.471	1.00
85_K	240_D	1.469	1.00
290_S	312_T	1.462	0.99
20_W	24_Q	1.459	0.99
10_V	270_V	1.451	0.99
80_E	275_M	1.440	0.99
383_L	397_V	1.439	0.99
376_E	408_F	1.416	0.99
12_E	17_Q	1.405	0.99
294_A	317_V	1.400	0.99
245_F	249_S	1.393	0.99
118_Q	345_L	1.391	0.99
25_T	335_E	1.390	0.99
296_A	300_R	1.380	0.99
105_L	244_V	1.357	0.99
84_S	214_L	1.356	0.99
324_F	389_I	1.349	0.99
337_A	387_V	1.349	0.99
13_I	66_Y	1.344	0.99
303_K	320_D	1.343	0.99
166_F	195_V	1.314	0.99
144_D	151_D	1.307	0.99
212_N	215_K	1.304	0.99
210_W	314_S	1.304	0.99
281_S	284_N	1.298	0.99
47_F	70_I	1.298	0.99
302_F	324_F	1.296	0.99
201_V	314_S	1.290	0.99
244_V	247_Q	1.286	0.99
303_K	323_Q	1.270	0.99
295_E	378_E	1.260	0.98
25_T	338_N	1.250	0.98
145_E	348_Y	1.248	0.98
47_F	67_T	1.247	0.98
402_I	406_R	1.238	0.98
87_C	236_A	1.233	0.98
100_A	252_I	1.231	0.98
57_Y	72_T	1.221	0.98
294_A	304_V	1.218	0.98
52_A	262_L	1.214	0.98
367_M	380_I	1.211	0.98
106_A	110_D	1.211	0.98
78_M	272_A	1.209	0.98
372_M	377_M	1.208	0.98
138_H	168_V	1.203	0.98
101_V	220_I	1.201	0.98
182_E	185_Q	1.190	0.98
292_A	378_E	1.188	0.98
110_D	165_K	1.186	0.98
223_V	272_A	1.185	0.98
300_R	386_K	1.183	0.98
208_K	280_E	1.183	0.98
379_E	382_E	1.178	0.98
198_A	238_F	1.177	0.98
11_L	15_K	1.173	0.98
144_D	154_K	1.172	0.98
293_L	297_L	1.169	0.98
74_T	269_A	1.162	0.97
195_V	222_T	1.157	0.97
27_N	340_I	1.157	0.97
143_F	348_Y	1.155	0.97
6_E	273_I	1.153	0.97
169_L	196_Y	1.150	0.97
180_T	210_W	1.144	0.97
62_Q	331_A	1.140	0.97
382_E	386_K	1.139	0.97
86_D	240_D	1.134	0.97
107_E	110_D	1.126	0.97
19_V	46_D	1.125	0.97
291_K	295_E	1.122	0.97
105_L	193_K	1.121	0.97
336_D	394_V	1.113	0.97
345_L	349_D	1.112	0.97
383_L	400_E	1.111	0.97
153_D	182_E	1.110	0.97
139_I	158_M	1.103	0.96
35_M	40_E	1.102	0.96
298_A	310_G	1.100	0.96
219_D	244_V	1.092	0.96
107_E	165_K	1.090	0.96
171_G	178_H	1.089	0.96
156_I	185_Q	1.088	0.96
379_E	407_N	1.078	0.96
300_R	378_E	1.078	0.96
116_P	140_E	1.070	0.96
333_L	387_V	1.070	0.96
188_H	219_D	1.066	0.96
84_S	238_F	1.066	0.96
4_P	11_L	1.066	0.96
297_L	385_K	1.062	0.96
352_E	356_D	1.057	0.96
106_A	112_A	1.057	0.96
181_K	217_G	1.053	0.95
86_D	248_V	1.048	0.95
240_D	244_V	1.047	0.95
169_L	194_L	1.045	0.95
193_K	244_V	1.043	0.95
26_L	372_M	1.034	0.95
67_T	262_L	1.032	0.95
198_A	205_I	1.031	0.95
341_V	360_L	1.021	0.95
177_P	210_W	1.018	0.94
396_E	400_E	1.014	0.94
326_G	352_E	1.013	0.94
324_F	385_K	1.012	0.94
99_A	256_F	1.010	0.94
184_A	219_D	1.005	0.94
295_E	298_A	1.003	0.94
303_K	310_G	1.003	0.94
114_I	124_S	1.001	0.94
115_A	142_P	0.998	0.94
387_V	394_V	0.995	0.94
288_R	373_K	0.990	0.94
116_P	119_A	0.990	0.94
334_L	341_V	0.990	0.94
52_A	64_T	0.985	0.93
114_I	140_E	0.984	0.93
232_P	267_A	0.981	0.93
113_L	139_I	0.974	0.93
103_R	136_I	0.971	0.93
300_R	389_I	0.970	0.93
152_V	155_A	0.969	0.93
104_V	251_T	0.967	0.93
131_L	135_G	0.967	0.93
102_F	112_A	0.965	0.93
338_N	402_I	0.964	0.93
230_P	369_R	0.959	0.93
290_S	365_Q	0.958	0.92
83_N	208_K	0.953	0.92
137_Q	162_V	0.952	0.92
10_V	13_I	0.952	0.92
14_T	42_V	0.951	0.92
400_E	403_E	0.951	0.92
8_E	12_E	0.950	0.92
252_I	256_F	0.949	0.92
85_K	239_S	0.948	0.92
7_L	77_L	0.947	0.92
173_L	318_A	0.944	0.92
337_A	383_L	0.940	0.92
332_K	336_D	0.938	0.92
10_V	47_F	0.935	0.92
317_V	362_I	0.933	0.91
171_G	201_V	0.927	0.91
24_Q	402_I	0.924	0.91
74_T	89_L	0.923	0.91
152_V	183_L	0.922	0.91
372_M	404_M	0.921	0.91
349_D	352_E	0.920	0.91
144_D	348_Y	0.919	0.91
160_E	190_V	0.917	0.91
159_I	167_V	0.916	0.91
9_K	273_I	0.913	0.91
160_E	163_K	0.912	0.91
243_E	247_Q	0.909	0.90
304_V	317_V	0.909	0.90
299_E	378_E	0.906	0.90
15_K	19_V	0.905	0.90
42_V	270_V	0.903	0.90
290_S	317_V	0.902	0.90
292_A	374_E	0.900	0.90
107_E	134_L	0.898	0.90
220_I	244_V	0.895	0.90
176_F	311_Y	0.889	0.89
193_K	220_I	0.887	0.89
302_F	319_V	0.884	0.89
96_I	99_A	0.878	0.89
236_A	272_A	0.876	0.89
9_K	12_E	0.873	0.89
158_M	161_E	0.872	0.88
401_V	404_M	0.869	0.88
394_V	397_V	0.868	0.88
171_G	314_S	0.865	0.88
102_F	138_H	0.862	0.88
283_A	286_I	0.861	0.88
178_H	183_L	0.858	0.88
395_N	398_K	0.857	0.88
119_A	145_E	0.857	0.88
329_K	333_L	0.856	0.88
326_G	329_K	0.850	0.87
37_P	41_S	0.849	0.87
281_S	285_Q	0.846	0.87
337_A	394_V	0.844	0.87
399_K	403_E	0.841	0.87
318_A	344_N	0.840	0.87
303_K	346_L	0.839	0.86
150_V	178_H	0.839	0.86
242_S	245_F	0.838	0.86
298_A	304_V	0.838	0.86
8_E	11_L	0.833	0.86
69_E	72_T	0.832	0.86
39_A	271_T	0.829	0.86
85_K	242_S	0.826	0.86
78_M	238_F	0.825	0.86
395_N	399_K	0.824	0.85
383_L	404_M	0.823	0.85
329_K	392_K	0.821	0.85
76_E	79_N	0.820	0.85
239_S	249_S	0.819	0.85
51_Y	226_H	0.818	0.85
157_K	160_E	0.816	0.85
222_T	237_I	0.816	0.85
167_V	183_L	0.812	0.85
181_K	184_A	0.809	0.84
101_V	106_A	0.809	0.84
3_L	14_T	0.805	0.84
376_E	407_N	0.803	0.84
10_V	273_I	0.801	0.84
6_E	38_L	0.800	0.84
376_E	404_M	0.794	0.83
118_Q	349_D	0.791	0.83
169_L	198_A	0.789	0.83
101_V	222_T	0.785	0.83
386_K	396_E	0.784	0.83
373_K	408_F	0.782	0.82
337_A	397_V	0.782	0.82
349_D	353_D	0.780	0.82
92_T	96_I	0.780	0.82
239_S	248_V	0.780	0.82
10_V	73_L	0.778	0.82
101_V	195_V	0.776	0.82
155_A	186_H	0.772	0.82
201_V	205_I	0.769	0.81
180_T	201_V	0.766	0.81
372_M	376_E	0.766	0.81
387_V	391_K	0.764	0.81
175_L	317_V	0.762	0.81
397_V	400_E	0.762	0.81
14_T	47_F	0.760	0.81
338_N	398_K	0.760	0.81
78_M	87_C	0.759	0.80
169_L	218_A	0.758	0.80
297_L	381_A	0.756	0.80
79_N	87_C	0.754	0.80
113_L	159_I	0.752	0.80
20_W	23_T	0.751	0.80
24_Q	338_N	0.750	0.80
329_K	391_K	0.750	0.80
333_L	390_D	0.747	0.79
85_K	244_V	0.747	0.79
128_F	138_H	0.745	0.79
214_L	221_M	0.744	0.79
372_M	408_F	0.742	0.79
112_A	166_F	0.741	0.79
116_P	142_P	0.734	0.78
145_E	148_I	0.734	0.78
115_A	178_H	0.734	0.78
230_P	282_Y	0.733	0.78
329_K	352_E	0.732	0.78
287_L	291_K	0.728	0.78
328_N	355_S	0.727	0.78
296_A	385_K	0.727	0.78
321_V	324_F	0.727	0.78
379_E	403_E	0.726	0.77
61_Y	226_H	0.726	0.77
381_A	385_K	0.724	0.77
317_V	364_V	0.723	0.77
378_E	382_E	0.723	0.77
247_Q	250_K	0.721	0.77
279_G	283_A	0.719	0.77
333_L	336_D	0.717	0.77
8_E	38_L	0.717	0.77
331_A	335_E	0.716	0.76
403_E	406_R	0.716	0.76
187_V	194_L	0.715	0.76
244_V	248_V	0.714	0.76
404_M	408_F	0.713	0.76
184_A	194_L	0.713	0.76
103_R	251_T	0.712	0.76
391_K	394_V	0.711	0.76
108_P	135_G	0.711	0.76
84_S	212_N	0.709	0.76
194_L	218_A	0.707	0.76
70_I	262_L	0.706	0.75
215_K	221_M	0.705	0.75
106_A	195_V	0.701	0.75
207_G	284_N	0.701	0.75
75_M	79_N	0.701	0.75
3_L	41_S	0.701	0.75
168_V	195_V	0.699	0.75
51_Y	61_Y	0.699	0.75
13_I	17_Q	0.698	0.75
181_K	215_K	0.697	0.75
113_L	162_V	0.697	0.75
95_T	252_I	0.696	0.74
198_A	206_E	0.695	0.74
131_L	136_I	0.693	0.74
103_R	256_F	0.692	0.74
78_M	82_T	0.690	0.74
239_S	244_V	0.690	0.74
283_A	365_Q	0.689	0.74
177_P	212_N	0.687	0.73
293_L	362_I	0.687	0.73
102_F	166_F	0.686	0.73
326_G	356_D	0.685	0.73
333_L	337_A	0.685	0.73
155_A	158_M	0.682	0.73
300_R	381_A	0.682	0.73
383_L	386_K	0.681	0.73
153_D	157_K	0.678	0.72
155_A	169_L	0.677	0.72
232_P	271_T	0.677	0.72
113_L	138_H	0.677	0.72
279_G	286_I	0.677	0.72
364_V	377_M	0.677	0.72
403_E	407_N	0.676	0.72
240_D	245_F	0.675	0.72
135_G	251_T	0.675	0.72
398_K	402_I	0.675	0.72
24_Q	406_R	0.669	0.71
202_Y	228_T	0.668	0.71
353_D	356_D	0.667	0.71
59_R	68_D	0.666	0.71
75_M	249_S	0.665	0.71
34_V	366_E	0.664	0.71
128_F	355_S	0.662	0.71
335_E	338_N	0.662	0.71
204_L	287_L	0.655	0.70
383_L	387_V	0.655	0.70
6_E	276_K	0.655	0.70
129_G	250_K	0.655	0.70
292_A	295_E	0.654	0.70
405_R	408_F	0.654	0.70
205_I	210_W	0.653	0.70
84_S	221_M	0.651	0.69
92_T	261_H	0.651	0.69
304_V	319_V	0.649	0.69
240_D	243_E	0.649	0.69
397_V	401_V	0.647	0.69
85_K	245_F	0.644	0.69
401_V	408_F	0.643	0.68
40_E	49_S	0.642	0.68
362_I	384_F	0.641	0.68
298_A	303_K	0.637	0.68
17_Q	20_W	0.634	0.67
207_G	280_E	0.633	0.67
65_K	335_E	0.632	0.67
151_D	154_K	0.632	0.67
297_L	304_V	0.631	0.67
231_G	271_T	0.631	0.67
278_F	281_S	0.630	0.67
51_Y	259_N	0.630	0.67
283_A	287_L	0.630	0.67
107_E	137_Q	0.627	0.67
232_P	264_R	0.626	0.66
115_A	152_V	0.625	0.66
156_I	186_H	0.625	0.66
335_E	340_I	0.625	0.66
332_K	335_E	0.623	0.66
105_L	166_F	0.622	0.66
32_E	51_Y	0.621	0.66
91_P	252_I	0.617	0.65
291_K	313_K	0.613	0.65
154_K	162_V	0.612	0.65
95_T	130_T	0.612	0.65
9_K	80_E	0.612	0.65
153_D	156_I	0.612	0.65
143_F	345_L	0.610	0.64
103_R	135_G	0.610	0.64
81_I	272_A	0.609	0.64
287_L	364_V	0.608	0.64
214_L	238_F	0.607	0.64
80_E	83_N	0.607	0.64
345_L	353_D	0.605	0.64
187_V	192_A	0.604	0.64
153_D	189_A	0.604	0.64
319_V	341_V	0.602	0.63
84_S	240_D	0.601	0.63
285_Q	368_T	0.600	0.63
11_L	41_S	0.600	0.63
169_L	178_H	0.599	0.63
390_D	394_V	0.599	0.63
99_A	130_T	0.598	0.63
302_F	389_I	0.597	0.63
230_P	274_E	0.596	0.63
401_V	405_R	0.595	0.63
175_L	306_G	0.593	0.62
214_L	217_G	0.593	0.62
321_V	346_L	0.593	0.62
180_T	205_I	0.592	0.62
292_A	377_M	0.592	0.62
73_L	273_I	0.592	0.62
296_A	377_M	0.591	0.62
215_K	240_D	0.589	0.62
98_N	222_T	0.588	0.62
274_E	282_Y	0.588	0.62
13_I	47_F	0.587	0.61
288_R	291_K	0.587	0.61
386_K	397_V	0.587	0.61
367_M	372_M	0.587	0.61
287_L	290_S	0.586	0.61
321_V	325_G	0.585	0.61
35_M	39_A	0.584	0.61
399_K	402_I	0.583	0.61
175_L	316_Q	0.583	0.61
95_T	99_A	0.582	0.61
111_K	158_M	0.581	0.61
74_T	272_A	0.581	0.61
95_T	102_F	0.580	0.61
3_L	38_L	0.579	0.60
302_F	384_F	0.579	0.60
225_T	236_A	0.578	0.60
35_M	267_A	0.578	0.60
14_T	46_D	0.577	0.60
251_T	256_F	0.575	0.60
219_D	245_F	0.574	0.60
114_I	138_H	0.574	0.60
35_M	48_M	0.573	0.60
246_K	250_K	0.572	0.60
375_G	382_E	0.572	0.60
79_N	84_S	0.572	0.60
377_M	380_I	0.571	0.59
286_I	364_V	0.570	0.59
207_G	212_N	0.570	0.59
305_I	321_V	0.569	0.59
261_H	264_R	0.568	0.59
43_Y	263_H	0.567	0.59
99_A	103_R	0.567	0.59
25_T	65_K	0.564	0.58
319_V	324_F	0.564	0.58
152_V	178_H	0.564	0.58
205_I	314_S	0.562	0.58
329_K	395_N	0.561	0.58
185_Q	189_A	0.561	0.58
326_G	357_P	0.560	0.58
144_D	149_N	0.560	0.58
394_V	398_K	0.560	0.58
239_S	242_S	0.560	0.58
334_L	360_L	0.558	0.58
85_K	243_E	0.557	0.58
302_F	323_Q	0.557	0.58
101_V	166_F	0.557	0.58
177_P	287_L	0.557	0.58
43_Y	46_D	0.555	0.57
92_T	95_T	0.554	0.57
345_L	355_S	0.554	0.57
9_K	69_E	0.553	0.57
239_S	247_Q	0.553	0.57
116_P	138_H	0.553	0.57
25_T	34_V	0.553	0.57
72_T	262_L	0.552	0.57
181_K	188_H	0.549	0.56
27_N	366_E	0.548	0.56
73_L	77_L	0.548	0.56
14_T	45_S	0.545	0.56
334_L	384_F	0.544	0.56
277_Y	281_S	0.544	0.56
268_T	272_A	0.543	0.56
40_E	46_D	0.543	0.56
276_K	281_S	0.542	0.55
113_L	140_E	0.541	0.55
32_E	226_H	0.540	0.55
79_N	85_K	0.540	0.55
382_E	400_E	0.540	0.55
62_Q	335_E	0.540	0.55
119_A	142_P	0.539	0.55
148_I	346_L	0.537	0.55
172_S	199_A	0.536	0.55
119_A	348_Y	0.536	0.55
103_R	131_L	0.536	0.55
58_K	355_S	0.536	0.55
262_L	265_L	0.535	0.55
376_E	379_E	0.535	0.55
106_A	165_K	0.533	0.54
242_S	246_K	0.532	0.54
179_P	182_E	0.530	0.54
99_A	135_G	0.529	0.54
82_T	202_Y	0.529	0.54
104_V	248_V	0.528	0.54
196_Y	201_V	0.528	0.54
199_A	222_T	0.528	0.54
209_V	288_R	0.527	0.53
202_Y	223_V	0.524	0.53
330_I	360_L	0.524	0.53
228_T	365_Q	0.523	0.53
9_K	73_L	0.522	0.53
240_D	247_Q	0.521	0.53
225_T	234_G	0.521	0.53
106_A	193_K	0.521	0.53
159_I	186_H	0.520	0.52
293_L	296_A	0.520	0.52
127_K	140_E	0.519	0.52
226_H	259_N	0.519	0.52
167_V	186_H	0.519	0.52
148_I	302_F	0.518	0.52
10_V	66_Y	0.516	0.52
112_A	140_E	0.516	0.52
77_L	270_V	0.513	0.52
324_F	388_I	0.513	0.52
149_N	176_F	0.512	0.51
286_I	290_S	0.511	0.51
62_Q	340_I	0.510	0.51
349_D	355_S	0.509	0.51
64_T	268_T	0.509	0.51
92_T	268_T	0.509	0.51
339_I	383_L	0.508	0.51
376_E	380_I	0.507	0.51
302_F	388_I	0.506	0.51
288_R	292_A	0.504	0.50
62_Q	343_K	0.503	0.50
140_E	158_M	0.503	0.50
207_G	287_L	0.503	0.50
302_F	381_A	0.503	0.50
112_A	165_K	0.502	0.50
66_Y	70_I	0.500	0.50

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1rv3A	3	0.9838	100	0.495	Contact Map
3ou5A	2	0.9053	100	0.517	Contact Map
3h7fA	2	0.9584	100	0.617	Contact Map
4wxgA	2	0.933	100	0.63	Contact Map
3n0lA	2	0.9076	100	0.65	Contact Map
3ecdA	2	0.8614	100	0.657	Contact Map
2dkjA	2	0.9238	100	0.664	Contact Map
3gbxA	2	0.8684	100	0.664	Contact Map
4bhdA	2	0.9492	100	0.67	Contact Map
4tn4A	2	0.9746	100	0.672	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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