GREMLIN Database
Q981C8 - ATP-dependent helicase
UniProt: Q981C8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 739 (676)
Sequences: 1953 (1467)
Seq/√Len: 56.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
227_E230_G5.2621.00
72_N231_V5.0161.00
512_I524_V3.9721.00
681_L719_D3.7651.00
318_K323_E3.7121.00
224_L229_F3.7021.00
256_S261_L3.6881.00
93_D97_K3.5981.00
91_I101_S3.5771.00
241_R244_G3.4541.00
229_F233_G3.3781.00
241_R248_H3.3421.00
94_L177_D3.3301.00
681_L685_K3.2791.00
255_N261_L3.2641.00
241_R246_A3.2451.00
240_R248_H3.1011.00
203_K211_I3.0121.00
377_L387_L2.9981.00
240_R246_A2.9741.00
681_L715_L2.9451.00
430_L434_W2.9421.00
225_F229_F2.8551.00
228_L231_V2.8501.00
620_T713_K2.8361.00
513_E525_R2.7411.00
240_R244_G2.6881.00
181_F199_A2.6801.00
426_K429_N2.6781.00
685_K719_D2.6561.00
225_F230_G2.6331.00
441_L444_E2.6041.00
75_I86_A2.5991.00
245_I248_H2.5861.00
224_L230_G2.5831.00
45_K49_I2.5591.00
241_R245_I2.5451.00
441_L445_S2.5311.00
179_F211_I2.4771.00
269_L344_A2.4701.00
254_G257_S2.4581.00
241_R249_S2.4571.00
314_K318_K2.4431.00
240_R245_I2.4211.00
246_A249_S2.4011.00
58_K240_R2.3801.00
429_N433_L2.3601.00
203_K231_V2.3541.00
224_L227_E2.3501.00
236_I240_R2.3501.00
426_K433_L2.3311.00
255_N258_R2.3061.00
244_G248_H2.2931.00
91_I180_I2.2741.00
184_V213_A2.2681.00
87_F105_Y2.2671.00
361_A373_V2.2641.00
242_R248_H2.2571.00
223_Y230_G2.2331.00
262_A376_I2.2251.00
58_K62_D2.2241.00
224_L228_L2.2221.00
223_Y227_E2.1961.00
71_E234_E2.1851.00
425_V429_N2.1851.00
429_N434_W2.1831.00
229_F232_E2.1731.00
241_R247_I2.1681.00
546_F550_D2.1651.00
546_F549_K2.1461.00
179_F203_K2.1311.00
88_L103_L2.1301.00
223_Y229_F2.1111.00
244_G249_S2.0901.00
226_E230_G2.0901.00
299_N325_D2.0891.00
224_L233_G2.0841.00
433_L437_A2.0311.00
198_L469_L2.0171.00
66_K236_I2.0141.00
94_L178_H2.0061.00
278_V346_I1.9961.00
331_P360_R1.9891.00
672_R675_Q1.9861.00
682_D686_S1.9841.00
244_G247_I1.9721.00
141_R144_L1.9611.00
430_L433_L1.9611.00
104_V154_T1.9581.00
240_R249_S1.9131.00
228_L232_E1.9041.00
226_E229_F1.9041.00
108_K155_N1.8981.00
564_M601_G1.8871.00
248_H252_D1.8831.00
438_Y441_L1.8671.00
67_I73_V1.8560.99
225_F233_G1.8350.99
236_I239_I1.8340.99
254_G258_R1.8320.99
228_L233_G1.8250.99
424_R434_W1.8150.99
227_E233_G1.8120.99
301_E506_S1.8070.99
620_T717_L1.7960.99
193_A403_F1.7950.99
345_V364_A1.7820.99
702_C706_N1.7810.99
426_K434_W1.7800.99
100_R150_H1.7750.99
240_R243_K1.7740.99
222_K235_I1.7610.99
622_H626_H1.7570.99
41_D93_D1.7520.99
229_F236_I1.7360.99
562_G603_L1.7360.99
130_G144_L1.7260.99
227_E232_E1.7220.99
431_P434_W1.7170.99
424_R433_L1.6950.99
668_L672_R1.6850.99
84_T88_L1.6820.99
438_Y444_E1.6790.99
622_H702_C1.6710.99
222_K228_L1.6690.99
49_I54_E1.6670.99
232_E236_I1.6570.99
65_R69_N1.6540.99
154_T159_I1.6530.99
425_V434_W1.6480.99
61_Y65_R1.6330.99
255_N259_W1.6320.99
243_K246_A1.6290.99
440_I444_E1.6200.99
167_T170_R1.6080.99
66_K73_V1.6070.99
169_F172_L1.6060.99
230_G236_I1.6020.98
42_D46_K1.5620.98
246_A252_D1.5540.98
242_R246_A1.5420.98
277_L345_V1.5300.98
277_L327_V1.5300.98
77_S81_T1.5250.98
63_A86_A1.5250.98
88_L118_V1.5240.98
429_N432_P1.5150.98
116_T320_R1.5060.98
230_G233_G1.5020.98
59_Y77_S1.4990.98
625_E629_I1.4980.98
241_R252_D1.4880.98
259_W262_A1.4780.97
261_L265_L1.4750.97
224_L231_V1.4700.97
223_Y228_L1.4700.97
226_E233_G1.4690.97
693_C696_C1.4570.97
425_V428_N1.4560.97
548_K551_E1.4550.97
438_Y442_A1.4520.97
438_Y445_S1.4410.97
68_K93_D1.4390.97
280_T286_A1.4370.97
543_L549_K1.4320.97
319_L327_V1.4320.97
56_L89_I1.4240.97
40_I48_I1.4210.97
623_A714_S1.4120.97
434_W441_L1.4070.97
46_K49_I1.3800.96
242_R245_I1.3770.96
40_I45_K1.3760.96
488_R497_L1.3750.96
226_E232_E1.3660.96
41_D44_L1.3530.96
95_A150_H1.3520.96
225_F228_L1.3410.95
62_D66_K1.3370.95
433_L444_E1.3370.95
679_V682_D1.3350.95
243_K248_H1.3350.95
626_H702_C1.3320.95
253_S257_S1.3310.95
263_A267_A1.3310.95
227_E231_V1.3300.95
59_Y81_T1.3280.95
437_A444_E1.3230.95
441_L447_A1.3200.95
261_L266_A1.3190.95
94_L99_E1.3120.95
136_T141_R1.3110.95
245_I249_S1.3110.95
70_K210_H1.3100.95
91_I178_H1.3080.95
225_F232_E1.3060.95
240_R247_I1.3030.95
433_L441_L1.3020.95
682_D685_K1.3010.95
261_L264_Y1.2900.94
253_S256_S1.2870.94
674_E678_E1.2740.94
435_K439_E1.2730.94
79_T110_L1.2720.94
64_Y89_I1.2710.94
228_L234_E1.2640.94
290_A302_V1.2620.94
108_K133_D1.2570.94
428_N431_P1.2570.94
233_G236_I1.2540.93
573_Y576_Y1.2520.93
286_A290_A1.2480.93
132_F158_M1.2470.93
67_I212_V1.2460.93
303_H332_T1.2460.93
317_E321_N1.2450.93
222_K230_G1.2440.93
72_N210_H1.2370.93
269_L372_L1.2330.93
424_R430_L1.2320.93
442_A445_S1.2310.93
132_F162_G1.2270.93
434_W444_E1.2230.93
74_M184_V1.2230.93
552_R674_E1.2230.93
433_L440_I1.2170.92
133_D136_T1.2100.92
256_S264_Y1.2100.92
673_L677_Y1.2070.92
173_L205_F1.2070.92
240_R252_D1.2060.92
574_V583_G1.2030.92
115_L119_Y1.2020.92
678_E682_D1.2000.92
424_R429_N1.1930.92
347_M361_A1.1880.91
95_A99_E1.1870.91
303_H307_L1.1840.91
196_R200_D1.1830.91
425_V433_L1.1780.91
236_I248_H1.1750.91
142_E147_N1.1720.91
426_K430_L1.1690.91
629_I645_G1.1590.90
167_T171_F1.1560.90
71_E232_E1.1490.90
185_H335_L1.1480.90
439_E442_A1.1470.90
235_I239_I1.1400.90
56_L178_H1.1390.90
73_V210_H1.1390.90
453_Y457_T1.1270.89
629_I647_S1.1270.89
281_D360_R1.1260.89
451_G454_V1.1180.89
288_L504_L1.1170.89
168_R172_L1.1160.89
583_G588_F1.1060.88
258_R262_A1.1020.88
275_K325_D1.1000.88
44_L48_I1.0990.88
91_I103_L1.0980.88
583_G590_E1.0980.88
585_N588_F1.0960.88
179_F199_A1.0930.88
689_C693_C1.0880.87
437_A440_I1.0880.87
222_K229_F1.0850.87
362_G365_G1.0840.87
502_V527_V1.0810.87
222_K225_F1.0800.87
459_E463_Y1.0800.87
700_P703_G1.0740.87
312_R316_E1.0740.87
108_K135_D1.0730.87
222_K233_G1.0730.87
301_E315_V1.0700.86
357_Y375_T1.0660.86
414_H417_A1.0650.86
86_A90_P1.0650.86
104_V155_N1.0610.86
304_R307_L1.0580.86
136_T144_L1.0570.86
424_R428_N1.0560.86
404_D668_L1.0560.86
516_D519_R1.0550.86
222_K226_E1.0530.86
417_A467_T1.0500.85
625_E647_S1.0500.85
434_W438_Y1.0480.85
285_M289_V1.0480.85
427_L430_L1.0460.85
224_L232_E1.0450.85
266_A278_V1.0450.85
430_L441_L1.0440.85
308_I311_E1.0410.85
625_E645_G1.0410.85
692_G698_Y1.0390.85
213_A229_F1.0380.85
262_A348_A1.0380.85
635_A675_Q1.0330.84
689_C696_C1.0320.84
280_T328_V1.0280.84
628_L655_I1.0270.84
249_S252_D1.0260.84
631_A683_I1.0250.84
102_V179_F1.0240.84
564_M570_V1.0240.84
454_V457_T1.0190.84
225_F231_V1.0180.84
430_L444_E1.0130.83
347_M360_R1.0110.83
430_L440_I1.0080.83
303_H316_E1.0070.83
205_F422_K1.0050.83
185_H359_Q1.0050.83
623_A697_V1.0020.83
463_Y466_T1.0020.83
112_R133_D1.0010.83
138_E142_E1.0010.83
277_L329_A1.0000.82
669_L676_A1.0000.82
242_R252_D0.9960.82
460_T464_V0.9950.82
265_L346_I0.9950.82
673_L676_A0.9940.82
46_K50_E0.9920.82
684_V715_L0.9910.82
435_K438_Y0.9890.82
418_Y421_E0.9870.82
206_K209_I0.9870.82
242_R247_I0.9860.82
382_I694_P0.9850.82
605_Y652_H0.9830.81
244_G252_D0.9820.81
543_L646_I0.9810.81
289_V293_A0.9800.81
85_E117_R0.9790.81
62_D65_R0.9780.81
66_K71_E0.9750.81
262_A267_A0.9720.81
713_K716_R0.9700.81
262_A268_V0.9690.80
434_W437_A0.9660.80
231_V236_I0.9660.80
440_I443_T0.9630.80
345_V373_V0.9620.80
132_F154_T0.9610.80
235_I238_G0.9600.80
79_T90_P0.9600.80
254_G262_A0.9580.80
627_V680_A0.9560.80
79_T362_G0.9540.79
129_V149_P0.9510.79
475_I479_Y0.9480.79
439_E443_T0.9470.79
540_S544_L0.9460.79
615_I618_M0.9450.79
676_A679_V0.9420.79
317_E671_E0.9390.78
504_L509_T0.9380.78
532_S535_T0.9360.78
236_I246_A0.9360.78
132_F136_T0.9340.78
583_G589_Y0.9330.78
260_T264_Y0.9290.78
476_V479_Y0.9280.77
567_V593_I0.9280.77
100_R175_T0.9280.77
694_P703_G0.9250.77
66_K234_E0.9230.77
633_R636_A0.9220.77
357_Y393_F0.9220.77
426_K438_Y0.9190.77
228_L235_I0.9120.76
44_L47_S0.9120.76
447_A450_V0.9110.76
622_H625_E0.9080.76
179_F394_F0.9070.76
330_T421_E0.9070.76
79_T365_G0.9060.76
350_N393_F0.9060.76
149_P360_R0.9050.76
430_L438_Y0.9050.76
684_V714_S0.9030.76
431_P441_L0.9030.76
478_I524_V0.9020.75
497_L522_A0.9010.75
216_A362_G0.9000.75
440_I445_S0.9000.75
236_I245_I0.8990.75
426_K431_P0.8970.75
154_T158_M0.8950.75
90_P110_L0.8940.75
450_V454_V0.8920.75
191_L195_I0.8910.75
88_L117_R0.8910.75
692_G697_V0.8910.75
95_A151_I0.8890.74
438_Y447_A0.8840.74
213_A231_V0.8840.74
116_T120_K0.8830.74
575_T585_N0.8820.74
642_D657_D0.8800.74
128_N150_H0.8800.74
254_G261_L0.8790.74
273_G361_A0.8790.74
567_V572_G0.8780.73
657_D661_G0.8720.73
502_V511_I0.8690.73
350_N375_T0.8650.72
40_I49_I0.8640.72
616_D619_E0.8630.72
429_N436_K0.8630.72
118_V151_I0.8620.72
224_L236_I0.8610.72
559_V574_V0.8580.72
87_F117_R0.8570.72
675_Q681_L0.8550.71
626_H629_I0.8550.71
579_Y586_E0.8540.71
74_M213_A0.8540.71
453_Y456_A0.8520.71
576_Y583_G0.8500.71
242_R249_S0.8500.71
431_P438_Y0.8500.71
41_D153_I0.8490.71
430_L437_A0.8470.71
508_K526_K0.8470.71
698_Y706_N0.8470.71
679_V683_I0.8450.71
601_G604_I0.8440.70
552_R559_V0.8430.70
353_S637_G0.8420.70
254_G259_W0.8410.70
622_H629_I0.8390.70
203_K208_D0.8390.70
86_A122_A0.8360.70
330_T337_I0.8330.69
60_Q82_G0.8320.69
60_Q83_K0.8320.69
256_S260_T0.8320.69
101_S493_A0.8310.69
645_G704_N0.8300.69
684_V718_I0.8280.69
566_L574_V0.8250.69
560_E563_D0.8250.69
684_V721_L0.8230.69
292_I295_R0.8220.68
290_A294_D0.8210.68
315_V327_V0.8150.68
499_P514_E0.8150.68
258_R261_L0.8140.68
699_S706_N0.8130.68
433_L442_A0.8110.67
389_H686_S0.8100.67
79_T216_A0.8090.67
111_A153_I0.8090.67
437_A441_L0.8090.67
110_L114_Q0.8070.67
113_D333_L0.8070.67
236_I244_G0.8060.67
694_P702_C0.8040.67
645_G703_G0.8040.67
254_G260_T0.8040.67
168_R171_F0.8030.67
110_L338_D0.8030.67
216_A334_E0.8010.66
569_R573_Y0.8010.66
583_G593_I0.8000.66
554_V557_E0.7990.66
107_T157_D0.7980.66
130_G149_P0.7970.66
431_P437_A0.7970.66
100_R171_F0.7970.66
243_K249_S0.7950.66
302_V506_S0.7950.66
577_D580_S0.7940.66
639_S654_V0.7930.66
316_E333_L0.7920.66
427_L431_P0.7900.65
573_Y587_Y0.7890.65
236_I241_R0.7880.65
318_K324_L0.7850.65
629_I699_S0.7830.65
561_Y600_K0.7820.65
73_V236_I0.7820.65
662_G689_C0.7810.64
494_L595_F0.7810.64
673_L683_I0.7790.64
68_K97_K0.7790.64
107_T335_L0.7790.64
262_A265_L0.7790.64
309_A313_I0.7780.64
95_A127_L0.7780.64
78_G355_T0.7770.64
432_P444_E0.7770.64
425_V430_L0.7760.64
76_I219_G0.7740.64
546_F565_K0.7730.64
577_D582_R0.7730.64
257_S261_L0.7710.63
497_L503_Y0.7710.63
566_L575_T0.7710.63
95_A101_S0.7690.63
676_A681_L0.7670.63
644_G658_S0.7650.63
565_K598_N0.7640.63
222_K227_E0.7630.63
566_L573_Y0.7630.63
562_G573_Y0.7620.63
257_S260_T0.7600.62
622_H706_N0.7580.62
275_K538_L0.7580.62
340_G367_R0.7580.62
181_F326_G0.7580.62
225_F236_I0.7580.62
716_R720_G0.7550.62
623_A709_L0.7540.62
632_A669_L0.7540.62
645_G648_Y0.7540.62
681_L684_V0.7530.62
478_I486_G0.7520.62
638_A642_D0.7520.62
563_D569_R0.7520.62
114_Q189_G0.7520.62
248_H357_Y0.7500.61
447_A455_L0.7500.61
112_R131_I0.7490.61
158_M371_G0.7490.61
227_E235_I0.7480.61
354_Y396_R0.7470.61
441_L455_L0.7470.61
153_I215_S0.7470.61
158_M162_G0.7460.61
567_V596_T0.7460.61
109_A114_Q0.7460.61
488_R492_A0.7450.61
357_Y479_Y0.7450.61
627_V684_V0.7440.61
439_E444_E0.7420.61
437_A445_S0.7420.61
258_R264_Y0.7410.60
320_R339_I0.7410.60
409_E667_K0.7410.60
110_L362_G0.7400.60
347_M357_Y0.7400.60
87_F214_S0.7390.60
59_Y109_A0.7380.60
645_G658_S0.7380.60
109_A359_Q0.7380.60
621_Y639_S0.7370.60
588_F592_P0.7360.60
431_P444_E0.7350.60
102_V700_P0.7340.60
565_K596_T0.7330.60
432_P435_K0.7320.59
40_I89_I0.7320.59
166_S169_F0.7310.59
435_K445_S0.7300.59
455_L458_P0.7300.59
704_N708_Y0.7290.59
398_I401_L0.7290.59
641_T701_Y0.7290.59
67_I210_H0.7260.59
311_E506_S0.7240.59
344_A372_L0.7230.59
161_L327_V0.7230.59
621_Y633_R0.7230.59
80_G99_E0.7220.58
166_S172_L0.7210.58
511_I527_V0.7210.58
660_I677_Y0.7200.58
359_Q363_R0.7190.58
248_H394_F0.7190.58
567_V573_Y0.7180.58
87_F158_M0.7180.58
288_L292_I0.7150.58
577_D584_K0.7150.58
570_V575_T0.7150.58
565_K569_R0.7140.58
488_R494_L0.7140.58
470_R478_I0.7140.58
158_M355_T0.7140.58
157_D470_R0.7140.58
697_V715_L0.7130.57
220_A223_Y0.7120.57
630_S640_L0.7110.57
287_E304_R0.7090.57
114_Q334_E0.7090.57
106_P363_R0.7090.57
157_D191_L0.7090.57
218_V224_L0.7080.57
253_S259_W0.7080.57
287_E316_E0.7060.57
531_L535_T0.7030.56
658_S703_G0.7030.56
157_D162_G0.7030.56
186_V335_L0.7030.56
407_N414_H0.7030.56
493_A498_Y0.7000.56
148_P152_L0.7000.56
629_I704_N0.6990.56
44_L96_L0.6970.56
453_Y458_P0.6970.56
158_M163_L0.6950.56
265_L357_Y0.6950.56
582_R588_F0.6940.55
111_A133_D0.6940.55
551_E558_K0.6930.55
701_Y704_N0.6930.55
436_K444_E0.6910.55
84_T117_R0.6910.55
584_K589_Y0.6900.55
430_L436_K0.6890.55
397_K483_K0.6890.55
608_L611_D0.6890.55
425_V432_P0.6850.54
321_N611_D0.6840.54
589_Y592_P0.6820.54
166_S206_K0.6820.54
605_Y624_T0.6820.54
201_R414_H0.6820.54
140_E143_R0.6810.54
141_R299_N0.6810.54
277_L280_T0.6800.54
710_S713_K0.6800.54
77_S109_A0.6780.54
188_E639_S0.6780.54
456_A461_K0.6780.54
42_D45_K0.6770.54
631_A666_S0.6770.54
86_A214_S0.6770.54
111_A131_I0.6750.53
703_G706_N0.6750.53
158_M187_Y0.6750.53
233_G240_R0.6750.53
258_R266_A0.6740.53
699_S703_G0.6740.53
688_N695_N0.6740.53
79_T333_L0.6720.53
472_V475_I0.6710.53
699_S702_C0.6710.53
273_G476_V0.6700.53
630_S633_R0.6700.53
91_I102_V0.6680.53
437_A465_A0.6680.53
216_A365_G0.6680.53
109_A113_D0.6660.52
79_T82_G0.6650.52
79_T83_K0.6650.52
433_L445_S0.6650.52
424_R441_L0.6620.52
243_K247_I0.6610.52
512_I515_F0.6600.52
59_Y283_Q0.6600.52
450_V455_L0.6590.52
633_R647_S0.6590.52
578_V582_R0.6570.51
352_P375_T0.6570.51
515_F522_A0.6560.51
437_A682_D0.6550.51
527_V531_L0.6550.51
57_Y340_G0.6540.51
79_T114_Q0.6540.51
448_K453_Y0.6530.51
692_G702_C0.6520.51
543_L547_N0.6520.51
334_E365_G0.6510.51
632_A643_L0.6510.51
404_D410_V0.6500.51
245_I370_A0.6500.51
189_G334_E0.6490.51
662_G696_C0.6490.51
263_A266_A0.6490.51
108_K111_A0.6490.51
80_G105_Y0.6480.50
444_E450_V0.6470.50
260_T263_A0.6470.50
597_Y601_G0.6470.50
430_L442_A0.6470.50
631_A680_A0.6460.50
108_K158_M0.6460.50
245_I252_D0.6450.50
553_E556_G0.6450.50
653_V699_S0.6440.50
611_D619_E0.6440.50
449_I682_D0.6430.50
215_S334_E0.6410.50
556_G559_V0.6390.49
113_D332_T0.6390.49
257_S263_A0.6390.49
564_M575_T0.6380.49
144_L656_Y0.6370.49
427_L435_K0.6370.49
459_E468_S0.6370.49
636_A666_S0.6360.49
566_L570_V0.6360.49
80_G494_L0.6350.49
433_L438_Y0.6350.49
109_A334_E0.6340.49
437_A442_A0.6330.49
431_P440_I0.6330.49
84_T184_V0.6320.49
174_R443_T0.6310.49
351_P362_G0.6310.49
232_E237_E0.6310.49
111_A162_G0.6300.48
675_Q679_V0.6280.48
610_D615_I0.6280.48
428_N449_I0.6280.48
547_N563_D0.6280.48
101_S178_H0.6280.48
556_G564_M0.6270.48
215_S381_P0.6270.48
576_Y581_K0.6250.48
634_V683_I0.6220.48
432_P437_A0.6220.48
135_D313_I0.6220.48
625_E705_N0.6210.47
338_D351_P0.6210.47
432_P441_L0.6200.47
639_S703_G0.6200.47
658_S701_Y0.6190.47
192_G201_R0.6190.47
104_V179_F0.6190.47
577_D585_N0.6180.47
160_H361_A0.6180.47
447_A454_V0.6180.47
257_S264_Y0.6180.47
519_R550_D0.6170.47
73_V606_H0.6160.47
694_P706_N0.6160.47
470_R473_G0.6150.47
571_E576_Y0.6150.47
426_K442_A0.6140.47
635_A679_V0.6140.47
462_K467_T0.6130.47
334_E359_Q0.6130.47
625_E703_G0.6120.47
267_A271_K0.6110.46
190_V410_V0.6110.46
376_I406_T0.6110.46
261_L268_V0.6100.46
429_N441_L0.6100.46
707_K712_K0.6100.46
547_N550_D0.6100.46
178_H212_V0.6090.46
257_S262_A0.6090.46
76_I715_L0.6080.46
450_V456_A0.6080.46
82_G106_P0.6070.46
83_K106_P0.6070.46
258_R265_L0.6070.46
307_L311_E0.6060.46
279_F284_Q0.6050.46
69_N178_H0.6040.46
340_G371_G0.6040.46
276_V639_S0.6030.46
56_L72_N0.6020.45
574_V586_E0.6020.45
474_P477_R0.6020.45
623_A629_I0.6010.45
87_F90_P0.6000.45
276_V346_I0.6000.45
352_P356_K0.5990.45
539_Y571_E0.5990.45
339_I342_I0.5990.45
467_T470_R0.5990.45
42_D50_E0.5990.45
100_R360_R0.5980.45
219_G353_S0.5970.45
483_K489_E0.5970.45
87_F371_G0.5950.45
640_L647_S0.5950.45
113_D330_T0.5950.45
137_P144_L0.5950.45
79_T334_E0.5940.45
132_F138_E0.5940.45
461_K465_A0.5940.45
493_A522_A0.5930.44
303_H306_G0.5930.44
684_V717_L0.5920.44
325_D335_L0.5920.44
76_I714_S0.5910.44
88_L417_A0.5910.44
260_T267_A0.5900.44
566_L571_E0.5900.44
614_L617_H0.5890.44
51_Y120_K0.5890.44
538_L544_L0.5880.44
489_E492_A0.5880.44
73_V212_V0.5870.44
110_L113_D0.5870.44
195_I286_A0.5870.44
680_A701_Y0.5870.44
463_Y468_S0.5870.44
708_Y713_K0.5870.44
562_G570_V0.5860.44
109_A365_G0.5850.44
447_A456_A0.5850.44
393_F396_R0.5850.44
292_I296_F0.5840.43
169_F173_L0.5840.43
647_S703_G0.5840.43
533_Y575_T0.5830.43
120_K167_T0.5820.43
254_G266_A0.5820.43
105_Y114_Q0.5820.43
67_I89_I0.5810.43
435_K441_L0.5810.43
588_F591_N0.5810.43
608_L613_T0.5810.43
535_T538_L0.5810.43
181_F213_A0.5800.43
358_V361_A0.5800.43
114_Q365_G0.5800.43
47_S50_E0.5770.43
56_L297_R0.5770.43
115_L153_I0.5770.43
430_L435_K0.5770.43
418_Y423_Y0.5760.43
640_L645_G0.5760.43
141_R187_Y0.5760.43
490_L595_F0.5750.43
289_V292_I0.5730.42
133_D306_G0.5720.42
702_C708_Y0.5720.42
685_K715_L0.5720.42
429_N444_E0.5710.42
445_S453_Y0.5700.42
629_I644_G0.5700.42
114_Q185_H0.5700.42
548_K605_Y0.5700.42
108_K113_D0.5700.42
316_E335_L0.5700.42
634_V658_S0.5690.42
199_A671_E0.5690.42
443_T458_P0.5690.42
682_D719_D0.5680.42
108_K304_R0.5680.42
98_G373_V0.5670.42
658_S699_S0.5660.42
239_I243_K0.5650.41
458_P465_A0.5650.41
568_M574_V0.5640.41
58_K179_F0.5640.41
646_I651_G0.5640.41
463_Y467_T0.5640.41
562_G576_Y0.5630.41
443_T678_E0.5620.41
363_R366_R0.5610.41
424_R440_I0.5610.41
581_K586_E0.5610.41
569_R582_R0.5610.41
578_V589_Y0.5610.41
610_D618_M0.5590.41
626_H638_A0.5590.41
577_D581_K0.5590.41
330_T333_L0.5590.41
59_Y196_R0.5590.41
675_Q680_A0.5570.41
344_A374_F0.5570.41
335_L507_K0.5570.41
670_F692_G0.5570.41
549_K600_K0.5560.41
337_I421_E0.5550.40
335_L381_P0.5550.40
462_K465_A0.5550.40
629_I632_A0.5550.40
646_I703_G0.5540.40
71_E244_G0.5540.40
544_L565_K0.5540.40
686_S712_K0.5530.40
576_Y589_Y0.5530.40
129_V198_L0.5530.40
303_H356_K0.5520.40
621_Y651_G0.5520.40
177_D444_E0.5510.40
105_Y340_G0.5500.40
160_H417_A0.5500.40
570_V589_Y0.5480.40
427_L433_L0.5480.40
192_G333_L0.5480.40
662_G693_C0.5480.40
291_K296_F0.5470.40
72_N229_F0.5470.40
156_P304_R0.5470.40
474_P496_D0.5460.39
81_T114_Q0.5460.39
602_L655_I0.5460.39
715_L719_D0.5460.39
690_E717_L0.5450.39
671_E682_D0.5450.39
611_D618_M0.5450.39
570_V573_Y0.5450.39
286_A304_R0.5440.39
641_T645_G0.5440.39
64_Y118_V0.5430.39
448_K451_G0.5420.39
436_K445_S0.5420.39
123_R339_I0.5410.39
690_E712_K0.5410.39
187_Y195_I0.5400.39
697_V703_G0.5400.39
460_T466_T0.5400.39
257_S265_L0.5390.39
481_D525_R0.5380.39
578_V584_K0.5370.39
223_Y226_E0.5370.39
211_I214_S0.5370.39
445_S449_I0.5360.38
492_A496_D0.5360.38
444_E451_G0.5350.38
578_V581_K0.5350.38
261_L267_A0.5350.38
703_G709_L0.5340.38
253_S258_R0.5340.38
63_A214_S0.5340.38
426_K449_I0.5340.38
643_L662_G0.5330.38
601_G605_Y0.5320.38
462_K466_T0.5320.38
275_K343_D0.5320.38
102_V199_A0.5310.38
454_V468_S0.5310.38
675_Q719_D0.5310.38
678_E686_S0.5300.38
107_T185_H0.5300.38
193_A291_K0.5300.38
554_V558_K0.5290.38
132_F371_G0.5290.38
391_E395_T0.5290.38
610_D614_L0.5290.38
384_S676_A0.5290.38
569_R593_I0.5290.38
171_F697_V0.5280.38
41_D46_K0.5280.38
488_R496_D0.5280.38
216_A351_P0.5270.38
576_Y584_K0.5270.38
107_T149_P0.5270.38
234_E682_D0.5270.38
629_I703_G0.5250.37
550_D671_E0.5250.37
560_E564_M0.5240.37
122_A125_L0.5240.37
645_G692_G0.5230.37
538_L541_M0.5230.37
625_E699_S0.5220.37
581_K584_K0.5220.37
533_Y548_K0.5220.37
674_E679_V0.5220.37
527_V537_P0.5220.37
96_L367_R0.5210.37
160_H414_H0.5210.37
532_S578_V0.5200.37
253_S260_T0.5200.37
110_L351_P0.5200.37
176_A632_A0.5200.37
42_D67_I0.5180.37
249_S372_L0.5180.37
644_G656_Y0.5180.37
259_W265_L0.5170.36
629_I709_L0.5170.36
574_V587_Y0.5170.36
407_N642_D0.5170.36
134_G312_R0.5170.36
461_K467_T0.5160.36
583_G586_E0.5150.36
442_A606_H0.5150.36
684_V707_K0.5150.36
237_E240_R0.5150.36
567_V570_V0.5140.36
675_Q678_E0.5130.36
350_N367_R0.5130.36
657_D664_G0.5120.36
613_T685_K0.5120.36
67_I178_H0.5120.36
109_A189_G0.5120.36
129_V150_H0.5120.36
202_I330_T0.5120.36
109_A351_P0.5110.36
86_A286_A0.5110.36
699_S709_L0.5110.36
573_Y577_D0.5110.36
376_I383_D0.5100.36
431_P442_A0.5090.36
384_S388_R0.5090.36
432_P439_E0.5080.36
93_D238_G0.5080.36
235_I252_D0.5080.36
622_H633_R0.5070.35
417_A421_E0.5060.35
232_E523_K0.5050.35
260_T265_L0.5050.35
197_N627_V0.5050.35
538_L543_L0.5050.35
195_I673_L0.5050.35
284_Q290_A0.5040.35
115_L373_V0.5040.35
184_V347_M0.5030.35
459_E467_T0.5030.35
114_Q192_G0.5030.35
646_I649_P0.5020.35
349_E352_P0.5010.35
580_S583_G0.5010.35
676_A684_V0.5010.35
644_G647_S0.5010.35
424_R431_P0.5010.35
595_F599_T0.5010.35
712_K715_L0.5010.35
392_E439_E0.5000.35
354_Y670_F0.5000.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ljyA 1 0.5643 100 0.624 Contact Map
4nhoA 1 0.5372 100 0.626 Contact Map
4pxaA 1 0.5453 100 0.63 Contact Map
4c9bA 1 0.5169 100 0.631 Contact Map
2db3A 1 0.5345 100 0.637 Contact Map
4a2qA 1 0.4452 100 0.638 Contact Map
4d25A 1 0.5399 100 0.64 Contact Map
3eiqA 1 0.4817 100 0.64 Contact Map
3fmpB 1 0.2882 100 0.643 Contact Map
3i5xA 1 0.6373 100 0.643 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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