Q981C8 - SULSO - GREMLIN Contacts

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Q981C8 - ATP-dependent helicase

UniProt:	Q981C8	Sequences: MEILSEVNDKLKTFNAKIAHVHTETFLEPEYGPSINEIDIDDKLKKSIIEYGIERLYKYQYDAYRKIKNKENVMIISGTGTGKTEAFLIPILDLALKGERSVLVYPTKALARDQLTRVYKLARELGLNVGIFDGDTPEKERERLYRNPPHILITNPDMIHLGLALSTRFRFLLRTADHFIFDEVHVYEGVLGAHIRNLADRIKEFKNDIHIVASSATVGATKYLFEELFGVEGEIIEGIRRRKGIAIHSIIDSGNSSRWTLAAYLAAVLVKNGLKVLVFTDSQQMAELVAKIADRFRVNLEVHRAGLIAEERIKVEEKLRNGELDGVVATPTLELGIDIGTIDAVIMAENPPSYTKYVQRAGRAGRRNNAGLVFTILGDDPIDSYYLRHPEEFFTRKIQALTFDPTNIEVIKIHALAYLAEKYRVKLNNLPPLWKKAYEILATESRAKIVGSYVLATPETKKYVATTSLRSVGPIVRIYEDKKKIGERELPAALHDLYPNAVYLISKKTYIIEEFDIDRLIAKVRKVNSELSYYTKPLYSMDLLEFNKKDEREVYGEKVEYGDMKLVMRVEGYVTYDVYSKRGKNEYFYENPISFTYNTKGLLIYHPLIDDFTLIDHMETYHATEHVLISAARVAAGASLTDLGGISYPSGHVVIYDSSIGGSGVSKLLFERLEQAYEVALDIVKSCNCEDGCPNCVYSPYCGNNNKYLSRKKSLRLIDGLIKGTIKGVNKDREGNPIA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	739 (676)
Sequences:	1953 (1467)
Seq/√Len:	56.4

BACSU - YPRA
SULSO - Q981C8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
227_E	230_G	5.262	1.00
72_N	231_V	5.016	1.00
512_I	524_V	3.972	1.00
681_L	719_D	3.765	1.00
318_K	323_E	3.712	1.00
224_L	229_F	3.702	1.00
256_S	261_L	3.688	1.00
93_D	97_K	3.598	1.00
91_I	101_S	3.577	1.00
241_R	244_G	3.454	1.00
229_F	233_G	3.378	1.00
241_R	248_H	3.342	1.00
94_L	177_D	3.330	1.00
681_L	685_K	3.279	1.00
255_N	261_L	3.264	1.00
241_R	246_A	3.245	1.00
240_R	248_H	3.101	1.00
203_K	211_I	3.012	1.00
377_L	387_L	2.998	1.00
240_R	246_A	2.974	1.00
681_L	715_L	2.945	1.00
430_L	434_W	2.942	1.00
225_F	229_F	2.855	1.00
228_L	231_V	2.850	1.00
620_T	713_K	2.836	1.00
513_E	525_R	2.741	1.00
240_R	244_G	2.688	1.00
181_F	199_A	2.680	1.00
426_K	429_N	2.678	1.00
685_K	719_D	2.656	1.00
225_F	230_G	2.633	1.00
441_L	444_E	2.604	1.00
75_I	86_A	2.599	1.00
245_I	248_H	2.586	1.00
224_L	230_G	2.583	1.00
45_K	49_I	2.559	1.00
241_R	245_I	2.545	1.00
441_L	445_S	2.531	1.00
179_F	211_I	2.477	1.00
269_L	344_A	2.470	1.00
254_G	257_S	2.458	1.00
241_R	249_S	2.457	1.00
314_K	318_K	2.443	1.00
240_R	245_I	2.421	1.00
246_A	249_S	2.401	1.00
58_K	240_R	2.380	1.00
429_N	433_L	2.360	1.00
203_K	231_V	2.354	1.00
224_L	227_E	2.350	1.00
236_I	240_R	2.350	1.00
426_K	433_L	2.331	1.00
255_N	258_R	2.306	1.00
244_G	248_H	2.293	1.00
91_I	180_I	2.274	1.00
184_V	213_A	2.268	1.00
87_F	105_Y	2.267	1.00
361_A	373_V	2.264	1.00
242_R	248_H	2.257	1.00
223_Y	230_G	2.233	1.00
262_A	376_I	2.225	1.00
58_K	62_D	2.224	1.00
224_L	228_L	2.222	1.00
223_Y	227_E	2.196	1.00
71_E	234_E	2.185	1.00
425_V	429_N	2.185	1.00
429_N	434_W	2.183	1.00
229_F	232_E	2.173	1.00
241_R	247_I	2.168	1.00
546_F	550_D	2.165	1.00
546_F	549_K	2.146	1.00
179_F	203_K	2.131	1.00
88_L	103_L	2.130	1.00
223_Y	229_F	2.111	1.00
244_G	249_S	2.090	1.00
226_E	230_G	2.090	1.00
299_N	325_D	2.089	1.00
224_L	233_G	2.084	1.00
433_L	437_A	2.031	1.00
198_L	469_L	2.017	1.00
66_K	236_I	2.014	1.00
94_L	178_H	2.006	1.00
278_V	346_I	1.996	1.00
331_P	360_R	1.989	1.00
672_R	675_Q	1.986	1.00
682_D	686_S	1.984	1.00
244_G	247_I	1.972	1.00
141_R	144_L	1.961	1.00
430_L	433_L	1.961	1.00
104_V	154_T	1.958	1.00
240_R	249_S	1.913	1.00
228_L	232_E	1.904	1.00
226_E	229_F	1.904	1.00
108_K	155_N	1.898	1.00
564_M	601_G	1.887	1.00
248_H	252_D	1.883	1.00
438_Y	441_L	1.867	1.00
67_I	73_V	1.856	0.99
225_F	233_G	1.835	0.99
236_I	239_I	1.834	0.99
254_G	258_R	1.832	0.99
228_L	233_G	1.825	0.99
424_R	434_W	1.815	0.99
227_E	233_G	1.812	0.99
301_E	506_S	1.807	0.99
620_T	717_L	1.796	0.99
193_A	403_F	1.795	0.99
345_V	364_A	1.782	0.99
702_C	706_N	1.781	0.99
426_K	434_W	1.780	0.99
100_R	150_H	1.775	0.99
240_R	243_K	1.774	0.99
222_K	235_I	1.761	0.99
622_H	626_H	1.757	0.99
41_D	93_D	1.752	0.99
229_F	236_I	1.736	0.99
562_G	603_L	1.736	0.99
130_G	144_L	1.726	0.99
227_E	232_E	1.722	0.99
431_P	434_W	1.717	0.99
424_R	433_L	1.695	0.99
668_L	672_R	1.685	0.99
84_T	88_L	1.682	0.99
438_Y	444_E	1.679	0.99
622_H	702_C	1.671	0.99
222_K	228_L	1.669	0.99
49_I	54_E	1.667	0.99
232_E	236_I	1.657	0.99
65_R	69_N	1.654	0.99
154_T	159_I	1.653	0.99
425_V	434_W	1.648	0.99
61_Y	65_R	1.633	0.99
255_N	259_W	1.632	0.99
243_K	246_A	1.629	0.99
440_I	444_E	1.620	0.99
167_T	170_R	1.608	0.99
66_K	73_V	1.607	0.99
169_F	172_L	1.606	0.99
230_G	236_I	1.602	0.98
42_D	46_K	1.562	0.98
246_A	252_D	1.554	0.98
242_R	246_A	1.542	0.98
277_L	345_V	1.530	0.98
277_L	327_V	1.530	0.98
77_S	81_T	1.525	0.98
63_A	86_A	1.525	0.98
88_L	118_V	1.524	0.98
429_N	432_P	1.515	0.98
116_T	320_R	1.506	0.98
230_G	233_G	1.502	0.98
59_Y	77_S	1.499	0.98
625_E	629_I	1.498	0.98
241_R	252_D	1.488	0.98
259_W	262_A	1.478	0.97
261_L	265_L	1.475	0.97
224_L	231_V	1.470	0.97
223_Y	228_L	1.470	0.97
226_E	233_G	1.469	0.97
693_C	696_C	1.457	0.97
425_V	428_N	1.456	0.97
548_K	551_E	1.455	0.97
438_Y	442_A	1.452	0.97
438_Y	445_S	1.441	0.97
68_K	93_D	1.439	0.97
280_T	286_A	1.437	0.97
543_L	549_K	1.432	0.97
319_L	327_V	1.432	0.97
56_L	89_I	1.424	0.97
40_I	48_I	1.421	0.97
623_A	714_S	1.412	0.97
434_W	441_L	1.407	0.97
46_K	49_I	1.380	0.96
242_R	245_I	1.377	0.96
40_I	45_K	1.376	0.96
488_R	497_L	1.375	0.96
226_E	232_E	1.366	0.96
41_D	44_L	1.353	0.96
95_A	150_H	1.352	0.96
225_F	228_L	1.341	0.95
62_D	66_K	1.337	0.95
433_L	444_E	1.337	0.95
679_V	682_D	1.335	0.95
243_K	248_H	1.335	0.95
626_H	702_C	1.332	0.95
253_S	257_S	1.331	0.95
263_A	267_A	1.331	0.95
227_E	231_V	1.330	0.95
59_Y	81_T	1.328	0.95
437_A	444_E	1.323	0.95
441_L	447_A	1.320	0.95
261_L	266_A	1.319	0.95
94_L	99_E	1.312	0.95
136_T	141_R	1.311	0.95
245_I	249_S	1.311	0.95
70_K	210_H	1.310	0.95
91_I	178_H	1.308	0.95
225_F	232_E	1.306	0.95
240_R	247_I	1.303	0.95
433_L	441_L	1.302	0.95
682_D	685_K	1.301	0.95
261_L	264_Y	1.290	0.94
253_S	256_S	1.287	0.94
674_E	678_E	1.274	0.94
435_K	439_E	1.273	0.94
79_T	110_L	1.272	0.94
64_Y	89_I	1.271	0.94
228_L	234_E	1.264	0.94
290_A	302_V	1.262	0.94
108_K	133_D	1.257	0.94
428_N	431_P	1.257	0.94
233_G	236_I	1.254	0.93
573_Y	576_Y	1.252	0.93
286_A	290_A	1.248	0.93
132_F	158_M	1.247	0.93
67_I	212_V	1.246	0.93
303_H	332_T	1.246	0.93
317_E	321_N	1.245	0.93
222_K	230_G	1.244	0.93
72_N	210_H	1.237	0.93
269_L	372_L	1.233	0.93
424_R	430_L	1.232	0.93
442_A	445_S	1.231	0.93
132_F	162_G	1.227	0.93
434_W	444_E	1.223	0.93
74_M	184_V	1.223	0.93
552_R	674_E	1.223	0.93
433_L	440_I	1.217	0.92
133_D	136_T	1.210	0.92
256_S	264_Y	1.210	0.92
673_L	677_Y	1.207	0.92
173_L	205_F	1.207	0.92
240_R	252_D	1.206	0.92
574_V	583_G	1.203	0.92
115_L	119_Y	1.202	0.92
678_E	682_D	1.200	0.92
424_R	429_N	1.193	0.92
347_M	361_A	1.188	0.91
95_A	99_E	1.187	0.91
303_H	307_L	1.184	0.91
196_R	200_D	1.183	0.91
425_V	433_L	1.178	0.91
236_I	248_H	1.175	0.91
142_E	147_N	1.172	0.91
426_K	430_L	1.169	0.91
629_I	645_G	1.159	0.90
167_T	171_F	1.156	0.90
71_E	232_E	1.149	0.90
185_H	335_L	1.148	0.90
439_E	442_A	1.147	0.90
235_I	239_I	1.140	0.90
56_L	178_H	1.139	0.90
73_V	210_H	1.139	0.90
453_Y	457_T	1.127	0.89
629_I	647_S	1.127	0.89
281_D	360_R	1.126	0.89
451_G	454_V	1.118	0.89
288_L	504_L	1.117	0.89
168_R	172_L	1.116	0.89
583_G	588_F	1.106	0.88
258_R	262_A	1.102	0.88
275_K	325_D	1.100	0.88
44_L	48_I	1.099	0.88
91_I	103_L	1.098	0.88
583_G	590_E	1.098	0.88
585_N	588_F	1.096	0.88
179_F	199_A	1.093	0.88
689_C	693_C	1.088	0.87
437_A	440_I	1.088	0.87
222_K	229_F	1.085	0.87
362_G	365_G	1.084	0.87
502_V	527_V	1.081	0.87
222_K	225_F	1.080	0.87
459_E	463_Y	1.080	0.87
700_P	703_G	1.074	0.87
312_R	316_E	1.074	0.87
108_K	135_D	1.073	0.87
222_K	233_G	1.073	0.87
301_E	315_V	1.070	0.86
357_Y	375_T	1.066	0.86
414_H	417_A	1.065	0.86
86_A	90_P	1.065	0.86
104_V	155_N	1.061	0.86
304_R	307_L	1.058	0.86
136_T	144_L	1.057	0.86
424_R	428_N	1.056	0.86
404_D	668_L	1.056	0.86
516_D	519_R	1.055	0.86
222_K	226_E	1.053	0.86
417_A	467_T	1.050	0.85
625_E	647_S	1.050	0.85
434_W	438_Y	1.048	0.85
285_M	289_V	1.048	0.85
427_L	430_L	1.046	0.85
224_L	232_E	1.045	0.85
266_A	278_V	1.045	0.85
430_L	441_L	1.044	0.85
308_I	311_E	1.041	0.85
625_E	645_G	1.041	0.85
692_G	698_Y	1.039	0.85
213_A	229_F	1.038	0.85
262_A	348_A	1.038	0.85
635_A	675_Q	1.033	0.84
689_C	696_C	1.032	0.84
280_T	328_V	1.028	0.84
628_L	655_I	1.027	0.84
249_S	252_D	1.026	0.84
631_A	683_I	1.025	0.84
102_V	179_F	1.024	0.84
564_M	570_V	1.024	0.84
454_V	457_T	1.019	0.84
225_F	231_V	1.018	0.84
430_L	444_E	1.013	0.83
347_M	360_R	1.011	0.83
430_L	440_I	1.008	0.83
303_H	316_E	1.007	0.83
205_F	422_K	1.005	0.83
185_H	359_Q	1.005	0.83
623_A	697_V	1.002	0.83
463_Y	466_T	1.002	0.83
112_R	133_D	1.001	0.83
138_E	142_E	1.001	0.83
277_L	329_A	1.000	0.82
669_L	676_A	1.000	0.82
242_R	252_D	0.996	0.82
460_T	464_V	0.995	0.82
265_L	346_I	0.995	0.82
673_L	676_A	0.994	0.82
46_K	50_E	0.992	0.82
684_V	715_L	0.991	0.82
435_K	438_Y	0.989	0.82
418_Y	421_E	0.987	0.82
206_K	209_I	0.987	0.82
242_R	247_I	0.986	0.82
382_I	694_P	0.985	0.82
605_Y	652_H	0.983	0.81
244_G	252_D	0.982	0.81
543_L	646_I	0.981	0.81
289_V	293_A	0.980	0.81
85_E	117_R	0.979	0.81
62_D	65_R	0.978	0.81
66_K	71_E	0.975	0.81
262_A	267_A	0.972	0.81
713_K	716_R	0.970	0.81
262_A	268_V	0.969	0.80
434_W	437_A	0.966	0.80
231_V	236_I	0.966	0.80
440_I	443_T	0.963	0.80
345_V	373_V	0.962	0.80
132_F	154_T	0.961	0.80
235_I	238_G	0.960	0.80
79_T	90_P	0.960	0.80
254_G	262_A	0.958	0.80
627_V	680_A	0.956	0.80
79_T	362_G	0.954	0.79
129_V	149_P	0.951	0.79
475_I	479_Y	0.948	0.79
439_E	443_T	0.947	0.79
540_S	544_L	0.946	0.79
615_I	618_M	0.945	0.79
676_A	679_V	0.942	0.79
317_E	671_E	0.939	0.78
504_L	509_T	0.938	0.78
532_S	535_T	0.936	0.78
236_I	246_A	0.936	0.78
132_F	136_T	0.934	0.78
583_G	589_Y	0.933	0.78
260_T	264_Y	0.929	0.78
476_V	479_Y	0.928	0.77
567_V	593_I	0.928	0.77
100_R	175_T	0.928	0.77
694_P	703_G	0.925	0.77
66_K	234_E	0.923	0.77
633_R	636_A	0.922	0.77
357_Y	393_F	0.922	0.77
426_K	438_Y	0.919	0.77
228_L	235_I	0.912	0.76
44_L	47_S	0.912	0.76
447_A	450_V	0.911	0.76
622_H	625_E	0.908	0.76
179_F	394_F	0.907	0.76
330_T	421_E	0.907	0.76
79_T	365_G	0.906	0.76
350_N	393_F	0.906	0.76
149_P	360_R	0.905	0.76
430_L	438_Y	0.905	0.76
684_V	714_S	0.903	0.76
431_P	441_L	0.903	0.76
478_I	524_V	0.902	0.75
497_L	522_A	0.901	0.75
216_A	362_G	0.900	0.75
440_I	445_S	0.900	0.75
236_I	245_I	0.899	0.75
426_K	431_P	0.897	0.75
154_T	158_M	0.895	0.75
90_P	110_L	0.894	0.75
450_V	454_V	0.892	0.75
191_L	195_I	0.891	0.75
88_L	117_R	0.891	0.75
692_G	697_V	0.891	0.75
95_A	151_I	0.889	0.74
438_Y	447_A	0.884	0.74
213_A	231_V	0.884	0.74
116_T	120_K	0.883	0.74
575_T	585_N	0.882	0.74
642_D	657_D	0.880	0.74
128_N	150_H	0.880	0.74
254_G	261_L	0.879	0.74
273_G	361_A	0.879	0.74
567_V	572_G	0.878	0.73
657_D	661_G	0.872	0.73
502_V	511_I	0.869	0.73
350_N	375_T	0.865	0.72
40_I	49_I	0.864	0.72
616_D	619_E	0.863	0.72
429_N	436_K	0.863	0.72
118_V	151_I	0.862	0.72
224_L	236_I	0.861	0.72
559_V	574_V	0.858	0.72
87_F	117_R	0.857	0.72
675_Q	681_L	0.855	0.71
626_H	629_I	0.855	0.71
579_Y	586_E	0.854	0.71
74_M	213_A	0.854	0.71
453_Y	456_A	0.852	0.71
576_Y	583_G	0.850	0.71
242_R	249_S	0.850	0.71
431_P	438_Y	0.850	0.71
41_D	153_I	0.849	0.71
430_L	437_A	0.847	0.71
508_K	526_K	0.847	0.71
698_Y	706_N	0.847	0.71
679_V	683_I	0.845	0.71
601_G	604_I	0.844	0.70
552_R	559_V	0.843	0.70
353_S	637_G	0.842	0.70
254_G	259_W	0.841	0.70
622_H	629_I	0.839	0.70
203_K	208_D	0.839	0.70
86_A	122_A	0.836	0.70
330_T	337_I	0.833	0.69
60_Q	82_G	0.832	0.69
60_Q	83_K	0.832	0.69
256_S	260_T	0.832	0.69
101_S	493_A	0.831	0.69
645_G	704_N	0.830	0.69
684_V	718_I	0.828	0.69
566_L	574_V	0.825	0.69
560_E	563_D	0.825	0.69
684_V	721_L	0.823	0.69
292_I	295_R	0.822	0.68
290_A	294_D	0.821	0.68
315_V	327_V	0.815	0.68
499_P	514_E	0.815	0.68
258_R	261_L	0.814	0.68
699_S	706_N	0.813	0.68
433_L	442_A	0.811	0.67
389_H	686_S	0.810	0.67
79_T	216_A	0.809	0.67
111_A	153_I	0.809	0.67
437_A	441_L	0.809	0.67
110_L	114_Q	0.807	0.67
113_D	333_L	0.807	0.67
236_I	244_G	0.806	0.67
694_P	702_C	0.804	0.67
645_G	703_G	0.804	0.67
254_G	260_T	0.804	0.67
168_R	171_F	0.803	0.67
110_L	338_D	0.803	0.67
216_A	334_E	0.801	0.66
569_R	573_Y	0.801	0.66
583_G	593_I	0.800	0.66
554_V	557_E	0.799	0.66
107_T	157_D	0.798	0.66
130_G	149_P	0.797	0.66
431_P	437_A	0.797	0.66
100_R	171_F	0.797	0.66
243_K	249_S	0.795	0.66
302_V	506_S	0.795	0.66
577_D	580_S	0.794	0.66
639_S	654_V	0.793	0.66
316_E	333_L	0.792	0.66
427_L	431_P	0.790	0.65
573_Y	587_Y	0.789	0.65
236_I	241_R	0.788	0.65
318_K	324_L	0.785	0.65
629_I	699_S	0.783	0.65
561_Y	600_K	0.782	0.65
73_V	236_I	0.782	0.65
662_G	689_C	0.781	0.64
494_L	595_F	0.781	0.64
673_L	683_I	0.779	0.64
68_K	97_K	0.779	0.64
107_T	335_L	0.779	0.64
262_A	265_L	0.779	0.64
309_A	313_I	0.778	0.64
95_A	127_L	0.778	0.64
78_G	355_T	0.777	0.64
432_P	444_E	0.777	0.64
425_V	430_L	0.776	0.64
76_I	219_G	0.774	0.64
546_F	565_K	0.773	0.64
577_D	582_R	0.773	0.64
257_S	261_L	0.771	0.63
497_L	503_Y	0.771	0.63
566_L	575_T	0.771	0.63
95_A	101_S	0.769	0.63
676_A	681_L	0.767	0.63
644_G	658_S	0.765	0.63
565_K	598_N	0.764	0.63
222_K	227_E	0.763	0.63
566_L	573_Y	0.763	0.63
562_G	573_Y	0.762	0.63
257_S	260_T	0.760	0.62
622_H	706_N	0.758	0.62
275_K	538_L	0.758	0.62
340_G	367_R	0.758	0.62
181_F	326_G	0.758	0.62
225_F	236_I	0.758	0.62
716_R	720_G	0.755	0.62
623_A	709_L	0.754	0.62
632_A	669_L	0.754	0.62
645_G	648_Y	0.754	0.62
681_L	684_V	0.753	0.62
478_I	486_G	0.752	0.62
638_A	642_D	0.752	0.62
563_D	569_R	0.752	0.62
114_Q	189_G	0.752	0.62
248_H	357_Y	0.750	0.61
447_A	455_L	0.750	0.61
112_R	131_I	0.749	0.61
158_M	371_G	0.749	0.61
227_E	235_I	0.748	0.61
354_Y	396_R	0.747	0.61
441_L	455_L	0.747	0.61
153_I	215_S	0.747	0.61
158_M	162_G	0.746	0.61
567_V	596_T	0.746	0.61
109_A	114_Q	0.746	0.61
488_R	492_A	0.745	0.61
357_Y	479_Y	0.745	0.61
627_V	684_V	0.744	0.61
439_E	444_E	0.742	0.61
437_A	445_S	0.742	0.61
258_R	264_Y	0.741	0.60
320_R	339_I	0.741	0.60
409_E	667_K	0.741	0.60
110_L	362_G	0.740	0.60
347_M	357_Y	0.740	0.60
87_F	214_S	0.739	0.60
59_Y	109_A	0.738	0.60
645_G	658_S	0.738	0.60
109_A	359_Q	0.738	0.60
621_Y	639_S	0.737	0.60
588_F	592_P	0.736	0.60
431_P	444_E	0.735	0.60
102_V	700_P	0.734	0.60
565_K	596_T	0.733	0.60
432_P	435_K	0.732	0.59
40_I	89_I	0.732	0.59
166_S	169_F	0.731	0.59
435_K	445_S	0.730	0.59
455_L	458_P	0.730	0.59
704_N	708_Y	0.729	0.59
398_I	401_L	0.729	0.59
641_T	701_Y	0.729	0.59
67_I	210_H	0.726	0.59
311_E	506_S	0.724	0.59
344_A	372_L	0.723	0.59
161_L	327_V	0.723	0.59
621_Y	633_R	0.723	0.59
80_G	99_E	0.722	0.58
166_S	172_L	0.721	0.58
511_I	527_V	0.721	0.58
660_I	677_Y	0.720	0.58
359_Q	363_R	0.719	0.58
248_H	394_F	0.719	0.58
567_V	573_Y	0.718	0.58
87_F	158_M	0.718	0.58
288_L	292_I	0.715	0.58
577_D	584_K	0.715	0.58
570_V	575_T	0.715	0.58
565_K	569_R	0.714	0.58
488_R	494_L	0.714	0.58
470_R	478_I	0.714	0.58
158_M	355_T	0.714	0.58
157_D	470_R	0.714	0.58
697_V	715_L	0.713	0.57
220_A	223_Y	0.712	0.57
630_S	640_L	0.711	0.57
287_E	304_R	0.709	0.57
114_Q	334_E	0.709	0.57
106_P	363_R	0.709	0.57
157_D	191_L	0.709	0.57
218_V	224_L	0.708	0.57
253_S	259_W	0.708	0.57
287_E	316_E	0.706	0.57
531_L	535_T	0.703	0.56
658_S	703_G	0.703	0.56
157_D	162_G	0.703	0.56
186_V	335_L	0.703	0.56
407_N	414_H	0.703	0.56
493_A	498_Y	0.700	0.56
148_P	152_L	0.700	0.56
629_I	704_N	0.699	0.56
44_L	96_L	0.697	0.56
453_Y	458_P	0.697	0.56
158_M	163_L	0.695	0.56
265_L	357_Y	0.695	0.56
582_R	588_F	0.694	0.55
111_A	133_D	0.694	0.55
551_E	558_K	0.693	0.55
701_Y	704_N	0.693	0.55
436_K	444_E	0.691	0.55
84_T	117_R	0.691	0.55
584_K	589_Y	0.690	0.55
430_L	436_K	0.689	0.55
397_K	483_K	0.689	0.55
608_L	611_D	0.689	0.55
425_V	432_P	0.685	0.54
321_N	611_D	0.684	0.54
589_Y	592_P	0.682	0.54
166_S	206_K	0.682	0.54
605_Y	624_T	0.682	0.54
201_R	414_H	0.682	0.54
140_E	143_R	0.681	0.54
141_R	299_N	0.681	0.54
277_L	280_T	0.680	0.54
710_S	713_K	0.680	0.54
77_S	109_A	0.678	0.54
188_E	639_S	0.678	0.54
456_A	461_K	0.678	0.54
42_D	45_K	0.677	0.54
631_A	666_S	0.677	0.54
86_A	214_S	0.677	0.54
111_A	131_I	0.675	0.53
703_G	706_N	0.675	0.53
158_M	187_Y	0.675	0.53
233_G	240_R	0.675	0.53
258_R	266_A	0.674	0.53
699_S	703_G	0.674	0.53
688_N	695_N	0.674	0.53
79_T	333_L	0.672	0.53
472_V	475_I	0.671	0.53
699_S	702_C	0.671	0.53
273_G	476_V	0.670	0.53
630_S	633_R	0.670	0.53
91_I	102_V	0.668	0.53
437_A	465_A	0.668	0.53
216_A	365_G	0.668	0.53
109_A	113_D	0.666	0.52
79_T	82_G	0.665	0.52
79_T	83_K	0.665	0.52
433_L	445_S	0.665	0.52
424_R	441_L	0.662	0.52
243_K	247_I	0.661	0.52
512_I	515_F	0.660	0.52
59_Y	283_Q	0.660	0.52
450_V	455_L	0.659	0.52
633_R	647_S	0.659	0.52
578_V	582_R	0.657	0.51
352_P	375_T	0.657	0.51
515_F	522_A	0.656	0.51
437_A	682_D	0.655	0.51
527_V	531_L	0.655	0.51
57_Y	340_G	0.654	0.51
79_T	114_Q	0.654	0.51
448_K	453_Y	0.653	0.51
692_G	702_C	0.652	0.51
543_L	547_N	0.652	0.51
334_E	365_G	0.651	0.51
632_A	643_L	0.651	0.51
404_D	410_V	0.650	0.51
245_I	370_A	0.650	0.51
189_G	334_E	0.649	0.51
662_G	696_C	0.649	0.51
263_A	266_A	0.649	0.51
108_K	111_A	0.649	0.51
80_G	105_Y	0.648	0.50
444_E	450_V	0.647	0.50
260_T	263_A	0.647	0.50
597_Y	601_G	0.647	0.50
430_L	442_A	0.647	0.50
631_A	680_A	0.646	0.50
108_K	158_M	0.646	0.50
245_I	252_D	0.645	0.50
553_E	556_G	0.645	0.50
653_V	699_S	0.644	0.50
611_D	619_E	0.644	0.50
449_I	682_D	0.643	0.50
215_S	334_E	0.641	0.50
556_G	559_V	0.639	0.49
113_D	332_T	0.639	0.49
257_S	263_A	0.639	0.49
564_M	575_T	0.638	0.49
144_L	656_Y	0.637	0.49
427_L	435_K	0.637	0.49
459_E	468_S	0.637	0.49
636_A	666_S	0.636	0.49
566_L	570_V	0.636	0.49
80_G	494_L	0.635	0.49
433_L	438_Y	0.635	0.49
109_A	334_E	0.634	0.49
437_A	442_A	0.633	0.49
431_P	440_I	0.633	0.49
84_T	184_V	0.632	0.49
174_R	443_T	0.631	0.49
351_P	362_G	0.631	0.49
232_E	237_E	0.631	0.49
111_A	162_G	0.630	0.48
675_Q	679_V	0.628	0.48
610_D	615_I	0.628	0.48
428_N	449_I	0.628	0.48
547_N	563_D	0.628	0.48
101_S	178_H	0.628	0.48
556_G	564_M	0.627	0.48
215_S	381_P	0.627	0.48
576_Y	581_K	0.625	0.48
634_V	683_I	0.622	0.48
432_P	437_A	0.622	0.48
135_D	313_I	0.622	0.48
625_E	705_N	0.621	0.47
338_D	351_P	0.621	0.47
432_P	441_L	0.620	0.47
639_S	703_G	0.620	0.47
658_S	701_Y	0.619	0.47
192_G	201_R	0.619	0.47
104_V	179_F	0.619	0.47
577_D	585_N	0.618	0.47
160_H	361_A	0.618	0.47
447_A	454_V	0.618	0.47
257_S	264_Y	0.618	0.47
519_R	550_D	0.617	0.47
73_V	606_H	0.616	0.47
694_P	706_N	0.616	0.47
470_R	473_G	0.615	0.47
571_E	576_Y	0.615	0.47
426_K	442_A	0.614	0.47
635_A	679_V	0.614	0.47
462_K	467_T	0.613	0.47
334_E	359_Q	0.613	0.47
625_E	703_G	0.612	0.47
267_A	271_K	0.611	0.46
190_V	410_V	0.611	0.46
376_I	406_T	0.611	0.46
261_L	268_V	0.610	0.46
429_N	441_L	0.610	0.46
707_K	712_K	0.610	0.46
547_N	550_D	0.610	0.46
178_H	212_V	0.609	0.46
257_S	262_A	0.609	0.46
76_I	715_L	0.608	0.46
450_V	456_A	0.608	0.46
82_G	106_P	0.607	0.46
83_K	106_P	0.607	0.46
258_R	265_L	0.607	0.46
307_L	311_E	0.606	0.46
279_F	284_Q	0.605	0.46
69_N	178_H	0.604	0.46
340_G	371_G	0.604	0.46
276_V	639_S	0.603	0.46
56_L	72_N	0.602	0.45
574_V	586_E	0.602	0.45
474_P	477_R	0.602	0.45
623_A	629_I	0.601	0.45
87_F	90_P	0.600	0.45
276_V	346_I	0.600	0.45
352_P	356_K	0.599	0.45
539_Y	571_E	0.599	0.45
339_I	342_I	0.599	0.45
467_T	470_R	0.599	0.45
42_D	50_E	0.599	0.45
100_R	360_R	0.598	0.45
219_G	353_S	0.597	0.45
483_K	489_E	0.597	0.45
87_F	371_G	0.595	0.45
640_L	647_S	0.595	0.45
113_D	330_T	0.595	0.45
137_P	144_L	0.595	0.45
79_T	334_E	0.594	0.45
132_F	138_E	0.594	0.45
461_K	465_A	0.594	0.45
493_A	522_A	0.593	0.44
303_H	306_G	0.593	0.44
684_V	717_L	0.592	0.44
325_D	335_L	0.592	0.44
76_I	714_S	0.591	0.44
88_L	417_A	0.591	0.44
260_T	267_A	0.590	0.44
566_L	571_E	0.590	0.44
614_L	617_H	0.589	0.44
51_Y	120_K	0.589	0.44
538_L	544_L	0.588	0.44
489_E	492_A	0.588	0.44
73_V	212_V	0.587	0.44
110_L	113_D	0.587	0.44
195_I	286_A	0.587	0.44
680_A	701_Y	0.587	0.44
463_Y	468_S	0.587	0.44
708_Y	713_K	0.587	0.44
562_G	570_V	0.586	0.44
109_A	365_G	0.585	0.44
447_A	456_A	0.585	0.44
393_F	396_R	0.585	0.44
292_I	296_F	0.584	0.43
169_F	173_L	0.584	0.43
647_S	703_G	0.584	0.43
533_Y	575_T	0.583	0.43
120_K	167_T	0.582	0.43
254_G	266_A	0.582	0.43
105_Y	114_Q	0.582	0.43
67_I	89_I	0.581	0.43
435_K	441_L	0.581	0.43
588_F	591_N	0.581	0.43
608_L	613_T	0.581	0.43
535_T	538_L	0.581	0.43
181_F	213_A	0.580	0.43
358_V	361_A	0.580	0.43
114_Q	365_G	0.580	0.43
47_S	50_E	0.577	0.43
56_L	297_R	0.577	0.43
115_L	153_I	0.577	0.43
430_L	435_K	0.577	0.43
418_Y	423_Y	0.576	0.43
640_L	645_G	0.576	0.43
141_R	187_Y	0.576	0.43
490_L	595_F	0.575	0.43
289_V	292_I	0.573	0.42
133_D	306_G	0.572	0.42
702_C	708_Y	0.572	0.42
685_K	715_L	0.572	0.42
429_N	444_E	0.571	0.42
445_S	453_Y	0.570	0.42
629_I	644_G	0.570	0.42
114_Q	185_H	0.570	0.42
548_K	605_Y	0.570	0.42
108_K	113_D	0.570	0.42
316_E	335_L	0.570	0.42
634_V	658_S	0.569	0.42
199_A	671_E	0.569	0.42
443_T	458_P	0.569	0.42
682_D	719_D	0.568	0.42
108_K	304_R	0.568	0.42
98_G	373_V	0.567	0.42
658_S	699_S	0.566	0.42
239_I	243_K	0.565	0.41
458_P	465_A	0.565	0.41
568_M	574_V	0.564	0.41
58_K	179_F	0.564	0.41
646_I	651_G	0.564	0.41
463_Y	467_T	0.564	0.41
562_G	576_Y	0.563	0.41
443_T	678_E	0.562	0.41
363_R	366_R	0.561	0.41
424_R	440_I	0.561	0.41
581_K	586_E	0.561	0.41
569_R	582_R	0.561	0.41
578_V	589_Y	0.561	0.41
610_D	618_M	0.559	0.41
626_H	638_A	0.559	0.41
577_D	581_K	0.559	0.41
330_T	333_L	0.559	0.41
59_Y	196_R	0.559	0.41
675_Q	680_A	0.557	0.41
344_A	374_F	0.557	0.41
335_L	507_K	0.557	0.41
670_F	692_G	0.557	0.41
549_K	600_K	0.556	0.41
337_I	421_E	0.555	0.40
335_L	381_P	0.555	0.40
462_K	465_A	0.555	0.40
629_I	632_A	0.555	0.40
646_I	703_G	0.554	0.40
71_E	244_G	0.554	0.40
544_L	565_K	0.554	0.40
686_S	712_K	0.553	0.40
576_Y	589_Y	0.553	0.40
129_V	198_L	0.553	0.40
303_H	356_K	0.552	0.40
621_Y	651_G	0.552	0.40
177_D	444_E	0.551	0.40
105_Y	340_G	0.550	0.40
160_H	417_A	0.550	0.40
570_V	589_Y	0.548	0.40
427_L	433_L	0.548	0.40
192_G	333_L	0.548	0.40
662_G	693_C	0.548	0.40
291_K	296_F	0.547	0.40
72_N	229_F	0.547	0.40
156_P	304_R	0.547	0.40
474_P	496_D	0.546	0.39
81_T	114_Q	0.546	0.39
602_L	655_I	0.546	0.39
715_L	719_D	0.546	0.39
690_E	717_L	0.545	0.39
671_E	682_D	0.545	0.39
611_D	618_M	0.545	0.39
570_V	573_Y	0.545	0.39
286_A	304_R	0.544	0.39
641_T	645_G	0.544	0.39
64_Y	118_V	0.543	0.39
448_K	451_G	0.542	0.39
436_K	445_S	0.542	0.39
123_R	339_I	0.541	0.39
690_E	712_K	0.541	0.39
187_Y	195_I	0.540	0.39
697_V	703_G	0.540	0.39
460_T	466_T	0.540	0.39
257_S	265_L	0.539	0.39
481_D	525_R	0.538	0.39
578_V	584_K	0.537	0.39
223_Y	226_E	0.537	0.39
211_I	214_S	0.537	0.39
445_S	449_I	0.536	0.38
492_A	496_D	0.536	0.38
444_E	451_G	0.535	0.38
578_V	581_K	0.535	0.38
261_L	267_A	0.535	0.38
703_G	709_L	0.534	0.38
253_S	258_R	0.534	0.38
63_A	214_S	0.534	0.38
426_K	449_I	0.534	0.38
643_L	662_G	0.533	0.38
601_G	605_Y	0.532	0.38
462_K	466_T	0.532	0.38
275_K	343_D	0.532	0.38
102_V	199_A	0.531	0.38
454_V	468_S	0.531	0.38
675_Q	719_D	0.531	0.38
678_E	686_S	0.530	0.38
107_T	185_H	0.530	0.38
193_A	291_K	0.530	0.38
554_V	558_K	0.529	0.38
132_F	371_G	0.529	0.38
391_E	395_T	0.529	0.38
610_D	614_L	0.529	0.38
384_S	676_A	0.529	0.38
569_R	593_I	0.529	0.38
171_F	697_V	0.528	0.38
41_D	46_K	0.528	0.38
488_R	496_D	0.528	0.38
216_A	351_P	0.527	0.38
576_Y	584_K	0.527	0.38
107_T	149_P	0.527	0.38
234_E	682_D	0.527	0.38
629_I	703_G	0.525	0.37
550_D	671_E	0.525	0.37
560_E	564_M	0.524	0.37
122_A	125_L	0.524	0.37
645_G	692_G	0.523	0.37
538_L	541_M	0.523	0.37
625_E	699_S	0.522	0.37
581_K	584_K	0.522	0.37
533_Y	548_K	0.522	0.37
674_E	679_V	0.522	0.37
527_V	537_P	0.522	0.37
96_L	367_R	0.521	0.37
160_H	414_H	0.521	0.37
532_S	578_V	0.520	0.37
253_S	260_T	0.520	0.37
110_L	351_P	0.520	0.37
176_A	632_A	0.520	0.37
42_D	67_I	0.518	0.37
249_S	372_L	0.518	0.37
644_G	656_Y	0.518	0.37
259_W	265_L	0.517	0.36
629_I	709_L	0.517	0.36
574_V	587_Y	0.517	0.36
407_N	642_D	0.517	0.36
134_G	312_R	0.517	0.36
461_K	467_T	0.516	0.36
583_G	586_E	0.515	0.36
442_A	606_H	0.515	0.36
684_V	707_K	0.515	0.36
237_E	240_R	0.515	0.36
567_V	570_V	0.514	0.36
675_Q	678_E	0.513	0.36
350_N	367_R	0.513	0.36
657_D	664_G	0.512	0.36
613_T	685_K	0.512	0.36
67_I	178_H	0.512	0.36
109_A	189_G	0.512	0.36
129_V	150_H	0.512	0.36
202_I	330_T	0.512	0.36
109_A	351_P	0.511	0.36
86_A	286_A	0.511	0.36
699_S	709_L	0.511	0.36
573_Y	577_D	0.511	0.36
376_I	383_D	0.510	0.36
431_P	442_A	0.509	0.36
384_S	388_R	0.509	0.36
432_P	439_E	0.508	0.36
93_D	238_G	0.508	0.36
235_I	252_D	0.508	0.36
622_H	633_R	0.507	0.35
417_A	421_E	0.506	0.35
232_E	523_K	0.505	0.35
260_T	265_L	0.505	0.35
197_N	627_V	0.505	0.35
538_L	543_L	0.505	0.35
195_I	673_L	0.505	0.35
284_Q	290_A	0.504	0.35
115_L	373_V	0.504	0.35
184_V	347_M	0.503	0.35
459_E	467_T	0.503	0.35
114_Q	192_G	0.503	0.35
646_I	649_P	0.502	0.35
349_E	352_P	0.501	0.35
580_S	583_G	0.501	0.35
676_A	684_V	0.501	0.35
644_G	647_S	0.501	0.35
424_R	431_P	0.501	0.35
595_F	599_T	0.501	0.35
712_K	715_L	0.501	0.35
392_E	439_E	0.500	0.35
354_Y	670_F	0.500	0.35

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ljyA	1	0.5643	100	0.624	Contact Map
4nhoA	1	0.5372	100	0.626	Contact Map
4pxaA	1	0.5453	100	0.63	Contact Map
4c9bA	1	0.5169	100	0.631	Contact Map
2db3A	1	0.5345	100	0.637	Contact Map
4a2qA	1	0.4452	100	0.638	Contact Map
4d25A	1	0.5399	100	0.64	Contact Map
3eiqA	1	0.4817	100	0.64	Contact Map
3fmpB	1	0.2882	100	0.643	Contact Map
3i5xA	1	0.6373	100	0.643	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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