Q981A5 - SULSO - GREMLIN Contacts

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Q981A5 - Heme bearing subunit I of the terminal oxidase (DoxB)

UniProt:	Q981A5	Sequences: MSDMGLKDVIVDIFQLDKDWTTRIVMGMLVLGVIWGLLGVIDSLMVRLVEASWGLSAVLPLTPQEYFAGITLHAERDLFGFAQQVIYAIFIYFTIKLLNIEPRAKWMLNLGFIAVNISMMFMEGPILIIPAAGFDNYFSATIWYYLSPLGIPGYSQYVVSPLFFWGWILLDAFTYIGGFWIVYHYYLASKNMKEKLPVPLVYFLMVTLMFMIGYSGVTAADVWDVLAFYHIVGLDPIANQIAFWIFGHAIVYMAWVPAVGALYLLIPMLANKPLYSDRMGRISALLYLIFSNNVPIHHLYMVNLPIALKLLQEVLTYSVVIPSMMTFFNLWATAKGADVKWNIITAWTVTSFAGAIAAGVTGISNATISFDAIVHNTDWVVGHFHAMILFSIVPAAWAVLYIMITMMSGRIWFSKGMAWLHYIGYMIGTTFLIVGFELIGFYGVVRRAEIYPRVPGLIDAEVIATVGAIIADLATLVWFLNLVLTLVKGRLVRLEGLSLPQVAGAVAMSLEWPSSISFTSPVLKFIKTHNTSKKGLASTIVLAIVGAILIVVSAVPLAFAGDAYTPQTWIWITILTIGIIFSAIGSLKGMKSI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	593 (489)
Sequences:	4253 (1445)
Seq/√Len:	65.3

ECOLI - CYOB
BACSU - QOX1 COX1
HALSA - COX1 Q9HN95
SULSO - Q981A5 Q97UN0 Q97VG9 Q97XY4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
436_F	464_A	4.758	1.00
31_L	112_F	4.688	1.00
265_L	398_A	4.272	1.00
404_I	485_T	3.828	1.00
343_I	418_A	3.762	1.00
32_G	85_V	3.710	1.00
35_W	119_M	3.662	1.00
365_N	380_V	3.590	1.00
258_A	395_A	3.514	1.00
343_I	415_K	3.375	1.00
202_Y	284_A	3.302	1.00
270_A	334_A	3.293	1.00
215_S	218_T	3.207	1.00
424_G	474_A	3.193	1.00
205_M	288_L	3.188	1.00
510_L	515_S	3.057	1.00
61_L	69_G	2.977	1.00
42_D	69_G	2.937	1.00
185_Y	204_L	2.931	1.00
510_L	513_P	2.828	1.00
94_T	185_Y	2.805	1.00
277_D	281_R	2.803	1.00
261_A	399_V	2.746	1.00
431_F	467_G	2.713	1.00
511_E	515_S	2.606	1.00
26_M	92_Y	2.594	1.00
214_Y	217_V	2.582	1.00
198_V	274_L	2.550	1.00
401_Y	421_H	2.480	1.00
266_I	352_F	2.470	1.00
386_A	430_T	2.422	1.00
14_F	23_R	2.377	1.00
145_Y	239_N	2.269	1.00
141_T	160_S	2.265	1.00
216_G	221_D	2.243	1.00
301_M	375_H	2.220	1.00
290_F	319_V	2.159	1.00
416_G	420_L	2.149	1.00
54_G	450_I	2.137	1.00
81_F	393_V	2.131	1.00
414_S	484_L	2.121	1.00
424_G	477_V	2.119	1.00
334_A	345_T	2.116	1.00
269_L	402_I	2.110	1.00
268_M	402_I	2.104	1.00
214_Y	218_T	2.053	1.00
320_V	363_I	2.024	1.00
218_T	221_D	1.992	1.00
350_T	426_M	1.974	1.00
512_W	515_S	1.972	1.00
428_G	470_I	1.969	1.00
215_S	221_D	1.965	1.00
75_E	145_Y	1.961	1.00
347_W	421_H	1.959	1.00
48_L	469_I	1.948	1.00
213_G	217_V	1.929	1.00
53_W	458_I	1.918	1.00
205_M	285_L	1.905	1.00
458_I	462_V	1.877	1.00
415_K	419_W	1.875	1.00
466_V	470_I	1.868	1.00
213_G	216_G	1.853	1.00
417_M	480_L	1.828	1.00
334_A	349_V	1.827	1.00
45_M	61_L	1.810	1.00
75_E	163_F	1.787	1.00
64_Q	68_A	1.736	1.00
63_P	449_E	1.730	1.00
417_M	420_L	1.713	0.99
397_W	478_W	1.707	0.99
417_M	477_V	1.693	0.99
364_S	379_W	1.683	0.99
39_G	76_R	1.671	0.99
246_F	250_I	1.664	0.99
45_M	69_G	1.661	0.99
421_H	425_Y	1.656	0.99
339_V	345_T	1.650	0.99
484_L	488_K	1.642	0.99
215_S	219_A	1.638	0.99
216_G	225_V	1.607	0.99
271_N	340_K	1.594	0.99
12_D	16_L	1.590	0.99
421_H	478_W	1.586	0.99
370_F	374_V	1.570	0.99
439_I	460_A	1.570	0.99
348_T	398_A	1.562	0.99
215_S	225_V	1.544	0.99
431_F	463_I	1.544	0.99
221_D	225_V	1.542	0.99
406_M	508_M	1.531	0.99
480_L	484_L	1.523	0.99
411_I	492_V	1.519	0.99
217_V	221_D	1.519	0.99
400_L	478_W	1.512	0.99
261_A	265_L	1.506	0.99
410_R	489_G	1.504	0.99
247_G	250_I	1.499	0.99
434_V	438_L	1.497	0.99
269_L	344_I	1.496	0.99
185_Y	200_L	1.486	0.98
37_L	479_F	1.486	0.98
31_L	116_N	1.486	0.98
240_Q	376_N	1.479	0.98
484_L	490_R	1.464	0.98
254_A	388_I	1.464	0.98
382_G	437_E	1.455	0.98
255_W	259_V	1.452	0.98
25_V	88_A	1.452	0.98
185_Y	196_L	1.449	0.98
214_Y	221_D	1.437	0.98
259_V	323_S	1.435	0.98
263_Y	330_L	1.434	0.98
80_G	119_M	1.432	0.98
216_G	220_A	1.426	0.98
397_W	421_H	1.425	0.98
144_Y	375_H	1.405	0.98
350_T	422_Y	1.398	0.98
31_L	115_V	1.392	0.98
144_Y	243_F	1.388	0.98
266_I	334_A	1.385	0.98
186_Y	204_L	1.383	0.98
469_I	473_L	1.369	0.97
267_P	274_L	1.369	0.97
214_Y	225_V	1.367	0.97
213_G	218_T	1.365	0.97
280_G	284_A	1.359	0.97
480_L	483_V	1.351	0.97
347_W	397_W	1.350	0.97
29_L	88_A	1.343	0.97
401_Y	418_A	1.341	0.97
44_L	472_D	1.338	0.97
410_R	485_T	1.335	0.97
141_T	150_G	1.334	0.97
80_G	170_L	1.333	0.97
354_G	430_T	1.332	0.97
112_F	116_N	1.326	0.97
44_L	468_A	1.322	0.97
182_V	204_L	1.321	0.97
261_A	403_M	1.319	0.97
93_F	402_I	1.314	0.97
186_Y	208_L	1.314	0.97
189_S	192_M	1.312	0.97
428_G	467_G	1.310	0.97
213_G	221_D	1.306	0.97
424_G	473_L	1.297	0.96
421_H	475_T	1.297	0.96
432_L	471_A	1.293	0.96
107_M	176_I	1.288	0.96
97_L	200_L	1.288	0.96
49_V	54_G	1.282	0.96
91_I	180_W	1.273	0.96
18_K	23_R	1.270	0.96
139_S	163_F	1.264	0.96
218_T	225_V	1.262	0.96
421_H	474_A	1.261	0.96
432_L	468_A	1.260	0.96
94_T	200_L	1.255	0.96
430_T	434_V	1.250	0.96
420_L	477_V	1.246	0.95
192_M	195_K	1.243	0.95
265_L	399_V	1.242	0.95
51_A	462_V	1.240	0.95
145_Y	163_F	1.237	0.95
386_A	434_V	1.236	0.95
41_I	45_M	1.230	0.95
244_W	247_G	1.225	0.95
38_L	76_R	1.206	0.95
217_V	225_V	1.206	0.95
421_H	477_V	1.206	0.95
147_S	239_N	1.204	0.95
38_L	42_D	1.203	0.95
459_D	463_I	1.201	0.94
438_L	460_A	1.201	0.94
466_V	469_I	1.200	0.94
90_F	203_F	1.193	0.94
287_Y	326_T	1.189	0.94
222_V	226_L	1.185	0.94
122_M	166_G	1.179	0.94
214_Y	223_W	1.178	0.94
86_I	396_A	1.178	0.94
109_N	113_I	1.175	0.94
72_L	126_I	1.172	0.94
193_K	197_P	1.170	0.94
205_M	284_A	1.169	0.94
87_Y	178_G	1.164	0.93
425_Y	474_A	1.161	0.93
91_I	108_L	1.157	0.93
215_S	223_W	1.156	0.93
347_W	401_Y	1.155	0.93
421_H	481_N	1.140	0.93
343_I	346_A	1.139	0.93
346_A	422_Y	1.137	0.93
371_D	380_V	1.135	0.93
313_E	368_I	1.134	0.93
29_L	407_M	1.132	0.93
395_A	398_A	1.131	0.92
29_L	85_V	1.127	0.92
46_V	69_G	1.126	0.92
93_F	407_M	1.124	0.92
217_V	223_W	1.124	0.92
425_Y	471_A	1.123	0.92
252_Y	257_P	1.122	0.92
178_G	207_T	1.118	0.92
206_V	253_M	1.117	0.92
48_L	57_A	1.116	0.92
343_I	419_W	1.110	0.92
262_L	351_S	1.105	0.92
281_R	284_A	1.104	0.92
18_K	109_N	1.103	0.92
212_I	215_S	1.099	0.91
476_L	480_L	1.094	0.91
265_L	348_T	1.084	0.91
365_N	374_V	1.074	0.90
49_V	56_S	1.074	0.90
255_W	392_I	1.070	0.90
13_I	17_D	1.070	0.90
317_Y	366_A	1.068	0.90
94_T	98_L	1.067	0.90
390_F	429_T	1.064	0.90
436_F	439_I	1.063	0.90
147_S	150_G	1.062	0.90
65_E	69_G	1.059	0.90
15_Q	27_G	1.057	0.90
316_T	366_A	1.057	0.90
301_M	372_A	1.056	0.90
262_L	266_I	1.055	0.90
20_W	23_R	1.050	0.89
479_F	483_V	1.046	0.89
416_G	419_W	1.041	0.89
145_Y	160_S	1.041	0.89
26_M	407_M	1.040	0.89
33_V	37_L	1.036	0.89
280_G	283_S	1.035	0.89
141_T	145_Y	1.032	0.89
36_G	39_G	1.032	0.89
110_L	114_A	1.029	0.88
346_A	419_W	1.023	0.88
118_S	166_G	1.018	0.88
49_V	450_I	1.017	0.88
31_L	35_W	1.017	0.88
418_A	481_N	1.017	0.88
462_V	466_V	1.010	0.87
334_A	337_A	1.009	0.87
85_V	396_A	1.007	0.87
36_G	81_F	1.006	0.87
111_G	176_I	1.003	0.87
269_L	345_T	0.996	0.87
81_F	85_V	0.995	0.87
216_G	219_A	0.995	0.87
76_R	123_E	0.994	0.87
151_I	154_Y	0.990	0.86
182_V	208_L	0.988	0.86
316_T	365_N	0.985	0.86
259_V	330_L	0.984	0.86
213_G	223_W	0.984	0.86
435_G	460_A	0.983	0.86
193_K	196_L	0.981	0.86
213_G	219_A	0.980	0.86
444_V	461_E	0.975	0.86
44_L	465_T	0.974	0.85
12_D	27_G	0.974	0.85
378_D	444_V	0.974	0.85
27_G	112_F	0.969	0.85
445_V	448_A	0.965	0.85
382_G	436_F	0.962	0.85
302_V	376_N	0.958	0.85
36_G	43_S	0.955	0.84
216_G	223_W	0.946	0.84
212_I	223_W	0.942	0.84
262_L	348_T	0.936	0.83
363_I	366_A	0.935	0.83
89_I	261_A	0.925	0.82
82_A	388_I	0.925	0.82
196_L	200_L	0.924	0.82
75_E	239_N	0.924	0.82
82_A	254_A	0.923	0.82
265_L	344_I	0.922	0.82
263_Y	326_T	0.918	0.82
271_N	498_S	0.917	0.82
15_Q	23_R	0.917	0.82
492_V	508_M	0.916	0.82
30_V	34_I	0.916	0.82
267_P	273_P	0.913	0.82
326_T	330_L	0.911	0.81
79_F	246_F	0.909	0.81
38_L	123_E	0.908	0.81
87_Y	92_Y	0.908	0.81
495_E	499_L	0.903	0.81
214_Y	224_D	0.902	0.81
400_L	482_L	0.900	0.81
334_A	339_V	0.898	0.80
180_W	184_H	0.897	0.80
87_Y	210_F	0.893	0.80
510_L	516_I	0.891	0.80
189_S	195_K	0.886	0.80
94_T	203_F	0.885	0.80
215_S	224_D	0.885	0.80
124_G	162_L	0.882	0.79
411_I	493_R	0.881	0.79
405_T	411_I	0.878	0.79
199_P	203_F	0.875	0.79
494_L	508_M	0.874	0.79
181_I	185_Y	0.874	0.79
98_L	200_L	0.874	0.79
489_G	492_V	0.873	0.79
24_I	108_L	0.873	0.79
50_E	378_D	0.870	0.78
194_E	282_I	0.870	0.78
237_I	302_V	0.867	0.78
250_I	254_A	0.862	0.78
46_V	74_A	0.858	0.77
483_V	487_V	0.856	0.77
452_P	455_P	0.854	0.77
125_P	139_S	0.850	0.77
52_S	55_L	0.846	0.76
82_A	392_I	0.845	0.76
388_I	392_I	0.844	0.76
358_A	387_M	0.843	0.76
255_W	391_S	0.841	0.76
145_Y	150_G	0.840	0.76
425_Y	475_T	0.839	0.76
216_G	245_I	0.839	0.76
386_A	437_E	0.837	0.76
214_Y	219_A	0.836	0.76
205_M	208_L	0.836	0.76
411_I	489_G	0.836	0.76
361_T	437_E	0.836	0.76
66_Y	70_I	0.834	0.75
350_T	394_P	0.832	0.75
139_S	145_Y	0.831	0.75
31_L	119_M	0.829	0.75
198_V	280_G	0.827	0.75
167_W	170_L	0.823	0.74
218_T	223_W	0.822	0.74
397_W	425_Y	0.819	0.74
91_I	102_P	0.818	0.74
343_I	347_W	0.818	0.74
259_V	324_M	0.817	0.74
83_Q	247_G	0.816	0.74
86_I	258_A	0.812	0.73
114_A	169_L	0.812	0.73
410_R	486_L	0.809	0.73
190_K	193_K	0.809	0.73
167_W	221_D	0.807	0.73
481_N	485_T	0.805	0.73
174_T	210_F	0.804	0.73
23_R	27_G	0.803	0.73
273_P	278_R	0.801	0.72
259_V	326_T	0.801	0.72
212_I	217_V	0.798	0.72
92_Y	407_M	0.798	0.72
508_M	511_E	0.797	0.72
506_V	510_L	0.797	0.72
43_S	390_F	0.794	0.72
64_Q	140_A	0.789	0.71
194_E	277_D	0.789	0.71
274_L	277_D	0.787	0.71
88_A	408_S	0.787	0.71
320_V	326_T	0.787	0.71
235_D	447_R	0.786	0.71
198_V	445_V	0.784	0.71
269_L	342_N	0.783	0.71
118_S	170_L	0.778	0.70
424_G	470_I	0.777	0.70
115_V	173_F	0.777	0.70
323_S	326_T	0.777	0.70
341_W	345_T	0.776	0.70
427_I	470_I	0.776	0.70
511_E	516_I	0.776	0.70
289_I	293_N	0.775	0.70
382_G	435_G	0.775	0.70
262_L	395_A	0.775	0.70
227_A	232_V	0.774	0.70
477_V	480_L	0.774	0.70
486_L	489_G	0.773	0.70
291_S	376_N	0.771	0.69
265_L	395_A	0.769	0.69
414_S	420_L	0.765	0.69
415_K	418_A	0.765	0.69
62_T	65_E	0.765	0.69
83_Q	210_F	0.764	0.69
340_K	498_S	0.762	0.69
57_A	61_L	0.761	0.68
360_V	363_I	0.760	0.68
167_W	222_V	0.760	0.68
506_V	511_E	0.758	0.68
356_I	360_V	0.757	0.68
464_A	467_G	0.757	0.68
246_F	254_A	0.755	0.68
296_I	304_L	0.755	0.68
218_T	222_V	0.754	0.68
344_I	402_I	0.753	0.68
102_P	108_L	0.753	0.68
353_A	357_A	0.749	0.67
463_I	467_G	0.747	0.67
56_S	450_I	0.747	0.67
37_L	41_I	0.747	0.67
321_I	325_M	0.745	0.67
212_I	219_A	0.744	0.67
392_I	396_A	0.744	0.67
414_S	480_L	0.742	0.66
86_I	392_I	0.742	0.66
197_P	200_L	0.741	0.66
466_V	476_L	0.740	0.66
202_Y	256_V	0.740	0.66
466_V	491_L	0.739	0.66
78_L	254_A	0.735	0.66
309_K	372_A	0.734	0.66
410_R	488_K	0.734	0.66
344_I	398_A	0.732	0.65
251_V	257_P	0.731	0.65
397_W	475_T	0.731	0.65
90_F	181_I	0.730	0.65
378_D	461_E	0.730	0.65
172_A	176_I	0.729	0.65
506_V	512_W	0.729	0.65
404_I	486_L	0.726	0.65
249_A	252_Y	0.725	0.65
490_R	493_R	0.724	0.65
15_Q	18_K	0.723	0.64
326_T	329_N	0.723	0.64
216_G	224_D	0.722	0.64
208_L	286_L	0.722	0.64
283_S	286_L	0.722	0.64
40_V	43_S	0.721	0.64
83_Q	246_F	0.721	0.64
39_G	78_L	0.720	0.64
223_W	226_L	0.719	0.64
168_I	223_W	0.719	0.64
360_V	390_F	0.718	0.64
247_G	254_A	0.717	0.64
202_Y	274_L	0.716	0.64
72_L	139_S	0.715	0.64
213_G	292_N	0.714	0.64
50_E	461_E	0.714	0.64
241_I	299_L	0.709	0.63
76_R	119_M	0.709	0.63
461_E	465_T	0.707	0.63
41_I	44_L	0.707	0.63
41_I	120_M	0.706	0.63
207_T	253_M	0.705	0.63
364_S	370_F	0.704	0.62
209_M	316_T	0.702	0.62
75_E	122_M	0.700	0.62
354_G	426_M	0.699	0.62
212_I	216_G	0.699	0.62
495_E	498_S	0.697	0.62
57_A	65_E	0.696	0.62
411_I	485_T	0.694	0.61
351_S	387_M	0.693	0.61
139_S	239_N	0.693	0.61
411_I	496_G	0.692	0.61
465_T	469_I	0.691	0.61
219_A	225_V	0.691	0.61
427_I	476_L	0.690	0.61
49_V	55_L	0.690	0.61
210_F	215_S	0.689	0.61
255_W	330_L	0.688	0.61
38_L	472_D	0.688	0.61
34_I	120_M	0.685	0.60
85_V	397_W	0.682	0.60
213_G	253_M	0.682	0.60
505_A	511_E	0.681	0.60
33_V	479_F	0.681	0.60
496_G	502_V	0.680	0.60
19_D	109_N	0.679	0.60
404_I	408_S	0.676	0.59
34_I	38_L	0.675	0.59
431_F	470_I	0.675	0.59
474_A	501_Q	0.675	0.59
165_W	169_L	0.674	0.59
82_A	393_V	0.674	0.59
81_F	348_T	0.673	0.59
37_L	347_W	0.672	0.59
141_T	155_S	0.671	0.59
219_A	226_L	0.671	0.59
61_L	65_E	0.671	0.59
241_I	437_E	0.671	0.59
327_F	352_F	0.670	0.59
139_S	160_S	0.670	0.59
259_V	283_S	0.669	0.58
40_V	475_T	0.669	0.58
208_L	288_L	0.669	0.58
280_G	329_N	0.668	0.58
93_F	97_L	0.668	0.58
164_F	239_N	0.667	0.58
507_A	511_E	0.665	0.58
346_A	423_I	0.665	0.58
48_L	465_T	0.663	0.58
81_F	203_F	0.663	0.58
254_A	392_I	0.663	0.58
369_S	374_V	0.663	0.58
496_G	508_M	0.662	0.58
155_S	158_V	0.661	0.58
345_T	348_T	0.660	0.57
280_G	325_M	0.660	0.57
472_D	476_L	0.659	0.57
484_L	487_V	0.658	0.57
397_W	401_Y	0.657	0.57
493_R	508_M	0.656	0.57
255_W	387_M	0.655	0.57
410_R	491_L	0.654	0.57
21_T	96_K	0.654	0.57
194_E	274_L	0.653	0.57
40_V	44_L	0.653	0.57
55_L	341_W	0.653	0.57
190_K	516_I	0.652	0.57
330_L	351_S	0.650	0.56
212_I	224_D	0.650	0.56
72_L	163_F	0.649	0.56
341_W	349_V	0.647	0.56
179_F	183_Y	0.647	0.56
313_E	367_T	0.645	0.56
255_W	258_A	0.644	0.56
212_I	221_D	0.641	0.55
477_V	481_N	0.641	0.55
75_E	141_T	0.641	0.55
110_L	176_I	0.640	0.55
37_L	475_T	0.639	0.55
52_S	462_V	0.639	0.55
428_G	474_A	0.638	0.55
181_I	207_T	0.637	0.55
107_M	111_G	0.636	0.55
401_Y	481_N	0.635	0.55
228_F	233_G	0.634	0.54
83_Q	250_I	0.634	0.54
24_I	27_G	0.633	0.54
269_L	497_L	0.632	0.54
337_A	418_A	0.631	0.54
46_V	70_I	0.630	0.54
220_A	225_V	0.630	0.54
111_G	181_I	0.629	0.54
21_T	296_I	0.629	0.54
311_L	315_L	0.629	0.54
147_S	225_V	0.628	0.54
342_N	345_T	0.628	0.54
300_Y	313_E	0.628	0.54
448_A	461_E	0.626	0.54
237_I	376_N	0.624	0.53
120_M	124_G	0.624	0.53
252_Y	359_G	0.621	0.53
99_N	409_G	0.621	0.53
170_L	173_F	0.620	0.53
380_V	384_F	0.617	0.52
369_S	388_I	0.617	0.52
82_A	396_A	0.616	0.52
512_W	516_I	0.615	0.52
425_Y	483_V	0.615	0.52
320_V	328_F	0.615	0.52
486_L	490_R	0.615	0.52
43_S	389_L	0.614	0.52
342_N	419_W	0.613	0.52
295_P	312_Q	0.612	0.52
117_I	120_M	0.611	0.52
66_Y	242_A	0.609	0.52
414_S	485_T	0.609	0.52
241_I	376_N	0.606	0.51
80_G	118_S	0.606	0.51
46_V	254_A	0.605	0.51
394_P	422_Y	0.604	0.51
408_S	411_I	0.604	0.51
275_Y	287_Y	0.600	0.50
78_L	83_Q	0.598	0.50
87_Y	90_F	0.598	0.50
173_F	235_D	0.597	0.50
270_A	339_V	0.596	0.50
28_M	91_I	0.595	0.50
406_M	504_G	0.595	0.50
469_I	472_D	0.595	0.50
103_R	177_G	0.594	0.50
249_A	257_P	0.594	0.50
505_A	512_W	0.594	0.50
408_S	485_T	0.591	0.49
171_D	326_T	0.588	0.49
488_K	491_L	0.587	0.49
248_H	297_H	0.587	0.49
279_M	283_S	0.586	0.49
210_F	247_G	0.586	0.49
52_S	483_V	0.585	0.49
268_M	501_Q	0.585	0.49
56_S	449_E	0.583	0.48
108_L	184_H	0.582	0.48
103_R	181_I	0.582	0.48
502_V	505_A	0.581	0.48
396_A	400_L	0.581	0.48
305_P	309_K	0.581	0.48
429_T	471_A	0.580	0.48
196_L	277_D	0.579	0.48
108_L	171_D	0.578	0.48
81_F	397_W	0.577	0.48
259_V	287_Y	0.577	0.48
148_P	236_P	0.576	0.48
290_F	322_P	0.576	0.48
381_V	441_F	0.575	0.48
427_I	431_F	0.574	0.47
431_F	466_V	0.572	0.47
193_K	499_L	0.572	0.47
44_L	57_A	0.572	0.47
192_M	415_K	0.571	0.47
37_L	472_D	0.570	0.47
388_I	391_S	0.570	0.47
275_Y	333_T	0.569	0.47
255_W	326_T	0.569	0.47
36_G	40_V	0.568	0.47
230_H	233_G	0.567	0.47
46_V	465_T	0.567	0.47
140_A	155_S	0.565	0.46
299_L	376_N	0.564	0.46
108_L	180_W	0.563	0.46
165_W	222_V	0.563	0.46
263_Y	320_V	0.563	0.46
105_K	183_Y	0.563	0.46
166_G	170_L	0.563	0.46
405_T	417_M	0.562	0.46
287_Y	330_L	0.562	0.46
304_L	308_L	0.561	0.46
404_I	410_R	0.561	0.46
55_L	449_E	0.560	0.46
86_I	110_L	0.560	0.46
238_A	352_F	0.559	0.46
240_Q	302_V	0.559	0.46
340_K	347_W	0.559	0.46
31_L	266_I	0.558	0.46
40_V	472_D	0.557	0.45
351_S	391_S	0.557	0.45
393_V	407_M	0.556	0.45
66_Y	137_Y	0.555	0.45
507_A	510_L	0.555	0.45
328_F	350_T	0.554	0.45
113_I	451_Y	0.553	0.45
81_F	400_L	0.552	0.45
356_I	391_S	0.552	0.45
190_K	195_K	0.552	0.45
398_A	404_I	0.551	0.45
259_V	263_Y	0.551	0.45
300_Y	368_I	0.551	0.45
313_E	464_A	0.550	0.45
374_V	380_V	0.550	0.45
489_G	496_G	0.550	0.45
150_G	224_D	0.550	0.45
91_I	181_I	0.549	0.45
496_G	499_L	0.549	0.45
279_M	375_H	0.549	0.45
32_G	81_F	0.547	0.44
320_V	323_S	0.547	0.44
327_F	387_M	0.547	0.44
460_A	463_I	0.547	0.44
74_A	384_F	0.547	0.44
21_T	25_V	0.546	0.44
91_I	171_D	0.546	0.44
414_S	417_M	0.545	0.44
90_F	207_T	0.545	0.44
170_L	174_T	0.545	0.44
125_P	128_I	0.544	0.44
142_I	447_R	0.544	0.44
76_R	122_M	0.542	0.44
278_R	282_I	0.542	0.44
152_P	156_Q	0.542	0.44
99_N	192_M	0.540	0.43
95_I	184_H	0.540	0.43
14_F	18_K	0.540	0.43
91_I	184_H	0.539	0.43
420_L	480_L	0.538	0.43
459_D	482_L	0.538	0.43
417_M	481_N	0.537	0.43
275_Y	329_N	0.537	0.43
342_N	402_I	0.535	0.43
217_V	226_L	0.533	0.43
45_M	427_I	0.532	0.43
347_W	422_Y	0.532	0.43
354_G	361_T	0.531	0.42
210_F	246_F	0.531	0.42
357_A	480_L	0.531	0.42
205_M	281_R	0.530	0.42
415_K	420_L	0.529	0.42
218_T	226_L	0.529	0.42
22_T	96_K	0.528	0.42
41_I	172_A	0.528	0.42
481_N	484_L	0.527	0.42
192_M	418_A	0.527	0.42
229_Y	234_L	0.526	0.42
47_R	50_E	0.524	0.42
123_E	126_I	0.524	0.42
104_A	184_H	0.524	0.42
210_F	250_I	0.523	0.42
342_N	346_A	0.522	0.41
406_M	509_S	0.522	0.41
452_P	456_G	0.521	0.41
221_D	224_D	0.521	0.41
405_T	492_V	0.520	0.41
42_D	45_M	0.520	0.41
202_Y	279_M	0.520	0.41
121_F	162_L	0.519	0.41
46_V	66_Y	0.519	0.41
146_L	355_A	0.518	0.41
266_I	348_T	0.518	0.41
438_L	442_Y	0.518	0.41
340_K	345_T	0.518	0.41
21_T	104_A	0.517	0.41
110_L	339_V	0.517	0.41
71_T	75_E	0.517	0.41
127_L	136_N	0.516	0.41
17_D	38_L	0.516	0.41
83_Q	391_S	0.515	0.41
387_M	391_S	0.513	0.40
436_F	448_A	0.513	0.40
280_G	326_T	0.511	0.40
13_I	18_K	0.511	0.40
192_M	502_V	0.510	0.40
480_L	491_L	0.510	0.40
473_L	477_V	0.510	0.40
342_N	415_K	0.509	0.40
22_T	406_M	0.508	0.40
386_A	391_S	0.508	0.40
28_M	108_L	0.508	0.40
120_M	123_E	0.508	0.40
420_L	483_V	0.508	0.40
223_W	229_Y	0.507	0.40
275_Y	326_T	0.507	0.40
496_G	507_A	0.507	0.40
358_A	376_N	0.506	0.40
100_I	188_A	0.505	0.40
327_F	356_I	0.504	0.39
303_N	355_A	0.503	0.39
126_I	136_N	0.503	0.39
493_R	497_L	0.502	0.39
122_M	228_F	0.502	0.39
285_L	476_L	0.502	0.39
366_A	369_S	0.502	0.39
44_L	469_I	0.501	0.39
137_Y	158_V	0.500	0.39
476_L	494_L	0.500	0.39
493_R	496_G	0.500	0.39
214_Y	220_A	0.500	0.39

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1fftA	1	0.8128	100	0.169	Contact Map
2yevA	1	0.9629	100	0.216	Contact Map
2gsmA	1	0.8246	100	0.276	Contact Map
1v54A	1	0.8398	100	0.288	Contact Map
3s8fA	1	0.8836	100	0.377	Contact Map
3ayfA	2	0.7825	100	0.421	Contact Map
3mk7A	1	0.742	100	0.439	Contact Map
3wfdB	1	0.715	100	0.448	Contact Map
1v54C	1	0.0995	96.6	0.966	Contact Map
1qleC	1	0.0995	96.3	0.966	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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