GREMLIN Database
Q980Z5 - Sun (Fmu) protein (Sun-2)
UniProt: Q980Z5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 368 (298)
Sequences: 6256 (4623)
Seq/√Len: 267.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
292_N324_I3.7411.00
288_K320_D3.5941.00
318_I363_L3.5751.00
301_K364_N3.1581.00
181_E251_K3.0981.00
301_K362_T2.9821.00
345_S359_F2.8881.00
184_V249_S2.8091.00
242_T289_S2.7731.00
288_K317_V2.6471.00
295_L321_Y2.6071.00
250_D298_K2.5761.00
87_K312_E2.4811.00
328_P366_T2.4541.00
116_D119_K2.4351.00
91_L311_P2.3391.00
206_E235_H2.3051.00
186_L294_A2.2621.00
224_L234_V2.1651.00
208_F249_S2.1561.00
254_L290_L2.1501.00
121_Y141_I2.1381.00
194_A209_L2.1151.00
292_N325_A2.1001.00
134_D166_K2.0831.00
134_D140_M2.0481.00
115_T120_V2.0221.00
303_V362_T2.0121.00
201_T205_A1.9631.00
203_N233_K1.9621.00
328_P364_N1.9601.00
98_K102_T1.9461.00
132_E144_N1.9341.00
211_D217_L1.9271.00
123_M160_K1.8901.00
120_V161_L1.8741.00
82_K86_D1.8551.00
177_P181_E1.8421.00
182_K206_E1.8241.00
80_F101_L1.8071.00
321_Y325_A1.8011.00
261_S308_S1.7971.00
315_E347_R1.7661.00
114_K228_G1.7651.00
154_S158_D1.7321.00
284_T317_V1.7271.00
178_E181_E1.7191.00
320_D324_I1.7041.00
261_S310_F1.6831.00
87_K310_F1.6681.00
172_V196_L1.6641.00
195_S227_C1.6571.00
121_Y131_F1.6391.00
306_V314_G1.6061.00
217_L236_I1.5891.00
140_M169_S1.5881.00
112_L139_Y1.5881.00
217_L238_Y1.5871.00
188_S220_E1.5581.00
197_Y253_L1.5111.00
316_K319_E1.5111.00
329_F361_S1.5091.00
108_A161_L1.5091.00
167_A355_T1.5051.00
174_A360_I1.4681.00
107_W142_K1.4291.00
291_L321_Y1.4111.00
319_E323_E1.4101.00
295_L302_L1.4011.00
112_L199_M1.4001.00
218_S221_Y1.3921.00
194_A207_T1.3801.00
115_T160_K1.3771.00
291_L302_L1.3631.00
127_Q155_I1.3631.00
175_L197_Y1.3561.00
117_I133_P1.3521.00
198_M229_V1.3501.00
311_P316_K1.3481.00
80_F100_K1.3381.00
88_L310_F1.3291.00
175_L251_K1.3271.00
296_K325_A1.3271.00
72_N82_K1.3241.00
92_L349_F1.3161.00
318_I322_Y1.3071.00
110_I120_V1.2981.00
288_K324_I1.2981.00
173_E200_L1.2841.00
171_V360_I1.2821.00
312_E316_K1.2661.00
100_K104_R1.2611.00
182_K208_F1.2501.00
162_I195_S1.2421.00
182_K248_K1.2311.00
137_F166_K1.2281.00
177_P201_T1.2201.00
188_S194_A1.2161.00
208_F237_I1.2131.00
155_I161_L1.2011.00
97_L101_L1.1981.00
348_T355_T1.1981.00
121_Y133_P1.1971.00
96_A351_H1.1941.00
285_K289_S1.1891.00
281_E312_E1.1851.00
293_E296_K1.1811.00
329_F345_S1.1771.00
182_K249_S1.1721.00
132_E142_K1.1701.00
288_K292_N1.1601.00
167_A348_T1.1511.00
97_L100_K1.1441.00
130_E144_N1.1391.00
251_K301_K1.1321.00
229_V234_V1.1281.00
176_K301_K1.1201.00
239_Q244_N1.1181.00
73_R77_E1.1151.00
332_Y336_Y1.1151.00
93_D96_A1.1141.00
117_I141_I1.1091.00
87_K277_G1.1061.00
196_L200_L1.1001.00
201_T204_R1.0951.00
107_W166_K1.0871.00
139_Y173_E1.0841.00
345_S361_S1.0811.00
122_R125_E1.0721.00
210_A237_I1.0681.00
331_N335_G1.0641.00
131_F141_I1.0641.00
176_K251_K1.0591.00
188_S209_L1.0591.00
276_N279_K1.0551.00
177_P183_L1.0491.00
114_K160_K1.0461.00
179_I204_R1.0431.00
108_A143_I1.0421.00
186_L241_S1.0401.00
259_S283_F1.0301.00
138_Y173_E1.0301.00
214_L238_Y1.0251.00
322_Y363_L1.0211.00
171_V196_L1.0181.00
172_V197_Y1.0181.00
332_Y335_G1.0121.00
195_S224_L1.0071.00
295_L327_K1.0061.00
241_S290_L1.0051.00
110_I117_I1.0031.00
253_L305_A1.0011.00
245_S293_E1.0011.00
165_D265_N1.0011.00
117_I121_Y1.0001.00
97_L104_R0.9951.00
195_S223_L0.9921.00
311_P315_E0.9921.00
140_M166_K0.9811.00
74_E85_E0.9731.00
136_D166_K0.9631.00
99_R103_E0.9581.00
177_P197_Y0.9561.00
134_D137_F0.9551.00
168_S358_F0.9531.00
155_I160_K0.9531.00
71_K89_F0.9511.00
177_P200_L0.9481.00
137_F140_M0.9461.00
186_L210_A0.9381.00
256_A290_L0.9371.00
221_Y225_K0.9341.00
280_I284_T0.9291.00
242_T290_L0.9271.00
97_L102_T0.9261.00
179_I202_E0.9251.00
284_T288_K0.9231.00
274_L279_K0.9201.00
197_Y251_K0.9121.00
293_E297_I0.9111.00
111_N114_K0.9081.00
210_A239_Q0.9081.00
162_I199_M0.9071.00
264_I270_I0.9041.00
187_S254_L0.9031.00
69_W72_N0.9021.00
279_K282_K0.9001.00
295_L325_A0.8861.00
86_D90_T0.8861.00
113_L229_V0.8821.00
85_E98_K0.8801.00
186_L254_L0.8721.00
244_N297_I0.8721.00
171_V305_A0.8711.00
75_N82_K0.8691.00
89_F94_V0.8691.00
282_K286_L0.8671.00
99_R102_T0.8661.00
269_S273_K0.8591.00
286_L289_S0.8591.00
330_S364_N0.8581.00
194_A234_V0.8551.00
175_L303_V0.8541.00
84_M261_S0.8541.00
171_V303_V0.8511.00
162_I223_L0.8491.00
221_Y236_I0.8481.00
217_L220_E0.8471.00
259_S280_I0.8471.00
127_Q154_S0.8441.00
183_L201_T0.8431.00
184_V210_A0.8421.00
183_L205_A0.8411.00
78_I85_E0.8401.00
254_L294_A0.8390.99
183_L251_K0.8390.99
84_M310_F0.8390.99
100_K103_E0.8360.99
263_M267_D0.8340.99
181_E301_K0.8340.99
331_N336_Y0.8290.99
198_M207_T0.8290.99
197_Y207_T0.8270.99
292_N320_D0.8220.99
245_S297_I0.8200.99
336_Y339_F0.8200.99
80_F85_E0.8170.99
75_N85_E0.8150.99
101_L104_R0.8140.99
210_A244_N0.8140.99
350_P357_G0.8100.99
89_F96_A0.8100.99
107_W134_D0.8090.99
322_Y327_K0.8090.99
175_L253_L0.8070.99
246_I296_K0.8050.99
194_A224_L0.8030.99
303_V360_I0.8020.99
83_W277_G0.8010.99
284_T312_E0.8010.99
165_D266_N0.8000.99
252_I294_A0.8000.99
70_L73_R0.7990.99
215_K219_K0.7980.99
334_S338_L0.7950.99
121_Y125_E0.7880.99
331_N334_S0.7870.99
184_V252_I0.7830.99
198_M233_K0.7760.99
208_F235_H0.7750.99
199_M229_V0.7690.99
98_K103_E0.7690.99
264_I271_L0.7650.99
341_S344_R0.7650.99
149_R152_S0.7630.99
170_I348_T0.7610.99
87_K91_L0.7570.99
321_Y327_K0.7560.99
215_K218_S0.7560.99
282_K285_K0.7550.99
288_K321_Y0.7530.99
277_G281_E0.7490.99
88_L97_L0.7480.99
333_Q337_S0.7470.99
315_E319_E0.7440.99
184_V297_I0.7430.99
222_N225_K0.7420.99
76_I79_K0.7410.99
186_L252_I0.7380.99
320_D323_E0.7380.99
80_F98_K0.7360.99
219_K222_N0.7360.99
117_I140_M0.7320.99
333_Q336_Y0.7280.99
122_R126_S0.7280.99
330_S362_T0.7250.99
302_L321_Y0.7220.98
176_K200_L0.7190.98
118_D122_R0.7190.98
84_M88_L0.7190.98
129_I153_L0.7140.98
73_R76_I0.7140.98
252_I302_L0.7130.98
113_L203_N0.7120.98
108_A141_I0.7110.98
295_L365_L0.7090.98
166_K355_T0.7090.98
244_N293_E0.7070.98
154_S157_K0.7040.98
115_T123_M0.7040.98
176_K181_E0.7020.98
162_I227_C0.7010.98
186_L290_L0.6990.98
96_A352_I0.6940.98
278_E282_K0.6930.98
331_N337_S0.6930.98
70_L94_V0.6900.98
139_Y196_L0.6880.98
119_K123_M0.6860.98
98_K101_L0.6840.98
319_E345_S0.6830.98
86_D89_F0.6820.98
137_F173_E0.6800.98
236_I239_Q0.6790.98
315_E345_S0.6780.98
204_R233_K0.6760.98
322_Y325_A0.6750.98
348_T353_D0.6710.98
133_P141_I0.6700.98
134_D142_K0.6650.97
222_N226_R0.6640.97
109_R195_S0.6620.97
330_S334_S0.6590.97
183_L197_Y0.6580.97
120_V123_M0.6570.97
284_T310_F0.6560.97
182_K298_K0.6560.97
110_I141_I0.6540.97
327_K366_T0.6540.97
224_L227_C0.6540.97
224_L236_I0.6530.97
340_K345_S0.6530.97
207_T229_V0.6520.97
291_L320_D0.6500.97
115_T119_K0.6490.97
84_M264_I0.6470.97
89_F93_D0.6460.97
203_N230_D0.6460.97
139_Y200_L0.6450.97
309_L357_G0.6440.97
346_N360_I0.6440.97
322_Y326_E0.6430.97
199_M227_C0.6420.97
266_N356_E0.6410.97
242_T286_L0.6400.97
218_S222_N0.6380.97
230_D233_K0.6370.97
317_V320_D0.6360.97
248_K298_K0.6360.97
314_G347_R0.6350.97
341_S345_S0.6350.97
197_Y205_A0.6340.97
156_V159_F0.6330.97
119_K122_R0.6310.96
331_N338_L0.6300.96
118_D133_P0.6290.96
174_A362_T0.6260.96
105_W142_K0.6260.96
334_S337_S0.6250.96
211_D270_I0.6240.96
281_E284_T0.6230.96
267_D273_K0.6220.96
340_K343_K0.6210.96
170_I346_N0.6210.96
322_Y329_F0.6190.96
91_L312_E0.6170.96
180_S204_R0.6160.96
239_Q243_K0.6150.96
165_D356_E0.6120.96
159_F226_R0.6100.96
120_V155_I0.6090.96
172_V200_L0.6090.96
351_H355_T0.6090.96
190_P216_R0.6090.96
211_D220_E0.6070.96
332_Y337_S0.6060.96
334_S339_F0.6050.96
117_I120_V0.6040.95
287_Q304_Y0.6040.95
123_M127_Q0.6030.95
127_Q153_L0.6030.95
107_W140_M0.6030.95
179_I201_T0.6020.95
109_R199_M0.6010.95
118_D121_Y0.6000.95
294_A302_L0.5980.95
74_E89_F0.5930.95
181_E201_T0.5920.95
239_Q245_S0.5900.95
88_L93_D0.5870.95
347_R350_P0.5860.95
113_L204_R0.5840.95
202_E205_A0.5830.95
280_I310_F0.5800.94
79_K272_L0.5800.94
333_Q338_L0.5770.94
177_P251_K0.5760.94
178_E251_K0.5750.94
254_L291_L0.5700.94
241_S244_N0.5700.94
125_E130_E0.5690.94
69_W73_R0.5660.94
125_E131_F0.5660.94
242_T293_E0.5660.94
181_E250_D0.5660.94
167_A171_V0.5630.93
261_S264_I0.5630.93
130_E145_R0.5630.93
348_T352_I0.5620.93
220_E236_I0.5620.93
330_S333_Q0.5620.93
85_E89_F0.5610.93
281_E285_K0.5590.93
246_I249_S0.5580.93
240_D245_S0.5550.93
292_N296_K0.5530.93
184_V208_F0.5520.93
344_R359_F0.5520.93
316_K320_D0.5510.93
135_K166_K0.5500.93
335_G339_F0.5500.93
335_G338_L0.5470.93
123_M155_I0.5470.93
344_R348_T0.5460.92
210_A241_S0.5440.92
80_F102_T0.5440.92
223_L226_R0.5410.92
123_M126_S0.5410.92
113_L199_M0.5400.92
87_K90_T0.5380.92
109_R164_H0.5380.92
142_K354_S0.5360.92
120_V124_L0.5290.91
261_S280_I0.5280.91
292_N321_Y0.5280.91
190_P220_E0.5240.91
211_D224_L0.5190.90
174_A177_P0.5170.90
309_L347_R0.5140.90
295_L363_L0.5140.90
333_Q339_F0.5130.90
284_T320_D0.5130.90
320_D325_A0.5120.90
279_K283_F0.5100.90
332_Y339_F0.5090.90
174_A346_N0.5080.90
68_Y72_N0.5070.89
210_A238_Y0.5070.89
68_Y73_R0.5050.89
201_T207_T0.5050.89
189_A223_L0.5050.89
214_L218_S0.5050.89
117_I139_Y0.5050.89
318_I361_S0.5040.89
283_F286_L0.5030.89
173_E196_L0.5020.89
249_S252_I0.5000.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2yxlA 1 0.9565 100 0.288 Contact Map
1sqgA 1 0.9375 100 0.309 Contact Map
2frxA 1 0.7554 100 0.385 Contact Map
1ixkA 1 0.7853 100 0.4 Contact Map
3m4xA 1 0.7554 100 0.419 Contact Map
3m6wA 2 0.7663 100 0.428 Contact Map
2b9eA 1 0.663 100 0.431 Contact Map
3ajdA 1 0.6522 100 0.508 Contact Map
4fzvA 1 0.7853 100 0.541 Contact Map
2vdvE 2 0.5109 99.8 0.797 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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