GREMLIN Database
Q980Z0 - Iron (III) ABC transporter, periplasmic-binding protein, putative
UniProt: Q980Z0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 273 (249)
Sequences: 15068 (11841)
Seq/√Len: 750.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
115_L139_Y4.0361.00
122_G131_A3.9291.00
206_D235_F3.9291.00
119_L132_R3.8671.00
141_V263_I3.5171.00
127_V130_K3.4011.00
123_N128_Y2.9851.00
25_S31_T2.8981.00
235_F239_N2.8891.00
119_L135_Y2.6921.00
143_D147_A2.5811.00
130_K133_E2.5751.00
178_I183_S2.4751.00
72_I75_Q2.4581.00
136_Y140_N2.4561.00
132_R136_Y2.4001.00
201_E204_K2.3421.00
155_K184_T2.2431.00
175_S179_S2.1601.00
24_V73_L2.1491.00
141_V259_T2.0571.00
23_I125_L2.0431.00
223_E227_S1.9781.00
133_E137_S1.9681.00
139_Y143_D1.9561.00
94_K97_G1.9321.00
39_L127_V1.9191.00
33_I118_V1.9181.00
39_L125_L1.9111.00
34_I125_L1.8961.00
144_G148_R1.8891.00
140_N144_G1.8851.00
226_Y240_K1.8361.00
208_D235_F1.8231.00
82_F121_I1.8151.00
209_I243_I1.7771.00
22_K44_K1.7761.00
92_T96_I1.7561.00
113_S116_N1.7361.00
129_E133_E1.7121.00
209_I241_R1.6951.00
234_L237_L1.6841.00
143_D146_R1.6411.00
222_K226_Y1.6201.00
93_R97_G1.5851.00
137_S141_V1.5731.00
89_K93_R1.5641.00
153_K184_T1.5081.00
130_K134_L1.4941.00
60_L72_I1.4821.00
103_Y124_V1.4801.00
69_N72_I1.4751.00
235_F238_L1.4731.00
68_V73_L1.4691.00
116_N119_L1.4641.00
233_D238_L1.4611.00
243_I268_V1.4511.00
116_N120_L1.4491.00
93_R96_I1.4371.00
74_K98_L1.4331.00
47_D50_S1.4261.00
115_L135_Y1.4211.00
103_Y120_L1.4181.00
145_L262_L1.4091.00
147_A150_Y1.3891.00
24_V76_I1.3801.00
223_E226_Y1.3731.00
88_Q91_L1.3561.00
45_A76_I1.3491.00
128_Y132_R1.3391.00
35_F56_A1.3251.00
142_I262_L1.3171.00
199_D228_I1.3081.00
37_L127_V1.3071.00
44_K76_I1.3011.00
136_Y139_Y1.2971.00
25_S34_I1.2971.00
129_E132_R1.2941.00
145_L266_K1.2911.00
210_I236_Q1.2821.00
156_V183_S1.2781.00
34_I39_L1.2761.00
120_L123_N1.2761.00
231_K237_L1.2571.00
264_W267_S1.2521.00
119_L139_Y1.2351.00
20_I79_D1.2281.00
140_N143_D1.2271.00
70_V94_K1.2191.00
118_V131_A1.2131.00
83_T104_P1.2081.00
71_D200_E1.2041.00
16_I19_P1.2041.00
201_E205_R1.1971.00
155_K208_D1.1961.00
141_V144_G1.1951.00
134_L137_S1.1941.00
164_G196_T1.1911.00
144_G147_A1.1911.00
24_V45_A1.1911.00
186_I205_R1.1851.00
35_F40_G1.1661.00
156_V178_I1.1521.00
21_T79_D1.1441.00
220_Y223_E1.1331.00
146_R180_L1.1311.00
22_K77_N1.1251.00
187_F205_R1.1171.00
154_I209_I1.1101.00
135_Y139_Y1.1021.00
170_F179_S1.0981.00
148_R266_K1.0961.00
159_E228_I1.0861.00
54_E57_R1.0831.00
137_S140_N1.0741.00
34_I82_F1.0711.00
221_E224_R1.0711.00
46_T61_K1.0671.00
146_R150_Y1.0591.00
224_R227_S1.0461.00
184_T188_D1.0391.00
263_I267_S1.0351.00
23_I80_I1.0191.00
154_I241_R1.0161.00
80_I103_Y1.0141.00
105_L120_L1.0091.00
142_I146_R1.0021.00
36_L134_L1.0001.00
157_Y167_T0.9861.00
32_E256_S0.9701.00
220_Y224_R0.9701.00
151_K154_I0.9641.00
231_K234_L0.9631.00
81_I99_G0.9561.00
19_P127_V0.9551.00
119_L123_N0.9521.00
131_A135_Y0.9521.00
122_G135_Y0.9511.00
16_I101_N0.9421.00
120_L124_V0.9401.00
138_L180_L0.9371.00
121_I125_L0.9371.00
211_I265_L0.9361.00
91_L94_K0.9351.00
212_Y244_F0.9301.00
176_D179_S0.9281.00
176_D180_L0.9261.00
141_V145_L0.9251.00
117_N120_L0.9211.00
109_T112_A0.9201.00
37_L134_L0.9201.00
149_C266_K0.9161.00
46_T59_T0.9161.00
246_K264_W0.9141.00
248_D252_H0.9091.00
110_N113_S0.8831.00
78_P81_I0.8821.00
158_I178_I0.8781.00
187_F190_I0.8751.00
18_R21_T0.8711.00
144_G263_I0.8591.00
38_G41_E0.8571.00
20_I80_I0.8541.00
33_I121_I0.8531.00
138_L142_I0.8511.00
229_L232_R0.8501.00
16_I20_I0.8461.00
101_N104_P0.8381.00
141_V266_K0.8381.00
30_S82_F0.8341.00
167_T187_F0.8271.00
237_L242_L0.8241.00
27_D84_T0.8201.00
23_I34_I0.8201.00
189_D205_R0.8151.00
187_F201_E0.8131.00
154_I183_S0.8131.00
133_E136_Y0.8111.00
32_E254_G0.8031.00
157_Y207_P0.8011.00
235_F241_R0.8001.00
19_P126_G0.7981.00
82_F124_V0.7971.00
37_L125_L0.7941.00
26_L81_I0.7881.00
232_R237_L0.7871.00
158_I213_E0.7861.00
198_K201_E0.7841.00
157_Y160_L0.7841.00
177_G262_L0.7821.00
203_L207_P0.7811.00
226_Y242_L0.7741.00
119_L122_G0.7721.00
212_Y242_L0.7651.00
40_G58_R0.7601.00
249_Y264_W0.7541.00
35_F55_D0.7531.00
211_I243_I0.7531.00
168_V194_Y0.7521.00
134_L138_L0.7521.00
38_G127_V0.7501.00
112_A116_N0.7451.00
125_L128_Y0.7451.00
115_L119_L0.7451.00
48_A61_K0.7441.00
256_S259_T0.7381.00
37_L130_K0.7341.00
172_T175_S0.7331.00
114_I138_L0.7281.00
112_A115_L0.7281.00
132_R135_Y0.7241.00
121_I124_V0.7231.00
225_F228_I0.7221.00
145_L149_C0.7201.00
62_I76_I0.7191.00
81_I98_L0.7151.00
90_E93_R0.7141.00
105_L121_I0.7131.00
96_I102_V0.7121.00
161_D164_G0.7111.00
197_P205_R0.6951.00
118_V134_L0.6921.00
202_I234_L0.6901.00
22_K79_D0.6881.00
249_Y252_H0.6841.00
37_L122_G0.6831.00
155_K186_I0.6811.00
142_I180_L0.6791.00
105_L117_N0.6781.00
264_W268_V0.6781.00
14_I92_T0.6771.00
38_G130_K0.6761.00
171_P175_S0.6721.00
228_I232_R0.6701.00
156_V159_E0.6651.00
115_L142_I0.6651.00
30_S105_L0.6641.00
183_S209_I0.6591.00
228_I231_K0.6591.00
81_I102_V0.6581.00
36_L256_S0.6571.00
169_G175_S0.6571.00
203_L233_D0.6561.00
115_L138_L0.6561.00
60_L63_G0.6551.00
259_T263_I0.6521.00
73_L95_L0.6511.00
181_L262_L0.6501.00
34_I121_I0.6491.00
215_K247_G0.6491.00
156_V160_L0.6491.00
36_L118_V0.6481.00
119_L128_Y0.6471.00
37_L118_V0.6471.00
185_N188_D0.6441.00
222_K244_F0.6391.00
102_V105_L0.6391.00
142_I145_L0.6371.00
24_V78_P0.6371.00
258_I261_V0.6371.00
30_S121_I0.6331.00
87_A91_L0.6301.00
45_A63_G0.6301.00
159_E210_I0.6301.00
64_S67_H0.6291.00
80_I124_V0.6271.00
168_V172_T0.6271.00
170_F190_I0.6261.00
52_R256_S0.6261.00
25_S30_S0.6231.00
83_T92_T0.6221.00
114_I118_V0.6201.00
71_D74_K0.6151.00
203_L234_L0.6111.00
14_I103_Y0.6101.00
175_S185_N0.6091.00
101_N105_L0.6081.00
70_V98_L0.6031.00
170_F188_D0.6011.00
16_I80_I0.5981.00
89_K92_T0.5961.00
138_L258_I0.5961.00
40_G55_D0.5961.00
135_Y138_L0.5951.00
168_V174_I0.5951.00
187_F197_P0.5931.00
157_Y202_I0.5931.00
213_E245_T0.5881.00
81_I95_L0.5881.00
115_L180_L0.5881.00
109_T113_S0.5881.00
37_L131_A0.5871.00
114_I257_F0.5871.00
181_L266_K0.5831.00
146_R149_C0.5811.00
185_N189_D0.5771.00
146_R181_L0.5721.00
207_P210_I0.5721.00
175_S188_D0.5651.00
70_V73_L0.5631.00
95_L102_V0.5631.00
72_I76_I0.5621.00
154_I208_D0.5611.00
95_L98_L0.5601.00
118_V135_Y0.5591.00
168_V175_S0.5581.00
63_G68_V0.5571.00
167_T197_P0.5561.00
40_G59_T0.5561.00
145_L258_I0.5561.00
59_T62_I0.5531.00
14_I96_I0.5521.00
154_I158_I0.5521.00
253_M261_V0.5501.00
17_Q101_N0.5501.00
15_K18_R0.5491.00
16_I124_V0.5491.00
210_I231_K0.5491.00
152_K155_K0.5481.00
82_F103_Y0.5461.00
153_K157_Y0.5451.00
25_S46_T0.5451.00
134_L255_P0.5451.00
211_I268_V0.5431.00
145_L148_R0.5431.00
31_T46_T0.5421.00
246_K249_Y0.5411.00
138_L141_V0.5411.00
263_I266_K0.5401.00
186_I189_D0.5391.00
158_I174_I0.5381.00
85_A88_Q0.5381.00
14_I17_Q0.5371.00
170_F175_S0.5371.00
155_K159_E0.5361.00
221_E225_F0.5351.00
222_K225_F0.5351.00
52_R56_A0.5321.00
254_G257_F0.5311.00
177_G265_L0.5311.00
214_P244_F0.5311.00
68_V91_L0.5311.00
199_D231_K0.5301.00
30_S33_I0.5291.00
155_K183_S0.5291.00
48_A51_Y0.5281.00
171_P191_S0.5281.00
178_I181_L0.5241.00
234_L238_L0.5231.00
209_I213_E0.5231.00
108_P113_S0.5221.00
177_G257_F0.5221.00
173_H176_D0.5221.00
221_E226_Y0.5201.00
112_A139_Y0.5191.00
206_D236_Q0.5151.00
92_T104_P0.5151.00
203_L230_R0.5151.00
20_I125_L0.5141.00
139_Y142_I0.5131.00
71_D75_Q0.5121.00
153_K156_V0.5111.00
96_I101_N0.5111.00
74_K200_E0.5111.00
179_S188_D0.5101.00
26_L68_V0.5101.00
70_V91_L0.5101.00
166_I196_T0.5091.00
262_L266_K0.5081.00
94_K98_L0.5061.00
231_K242_L0.5061.00
111_I114_I0.5031.00
35_F59_T0.5011.00
24_V81_I0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4hn9A 1 0.9817 100 0.154 Contact Map
4m7oA 1 0.9194 100 0.16 Contact Map
3pshA 1 0.978 100 0.162 Contact Map
4pagA 2 0.9707 100 0.169 Contact Map
4ovkA 1 0.9817 100 0.172 Contact Map
4mlzA 1 0.978 100 0.187 Contact Map
4n01A 1 0.9853 100 0.197 Contact Map
4ljsA 1 0.978 100 0.198 Contact Map
4mo9A 1 0.9817 100 0.207 Contact Map
3tefA 1 0.9597 100 0.21 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0096 seconds.