GREMLIN Database
Q980Y8 - Uncharacterized protein
UniProt: Q980Y8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 236 (215)
Sequences: 132 (115)
Seq/√Len: 7.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
128_F148_L4.5760.99
79_A83_L4.0560.97
20_S223_L3.1400.89
34_W79_A3.1370.89
23_D27_R3.0670.88
28_E31_P3.0060.87
139_P213_A2.5410.76
21_I25_K2.4270.72
66_L110_L2.4040.72
152_R213_A2.3770.71
16_L226_Y2.2320.66
118_I154_K2.0600.59
21_I125_L2.0510.59
39_P125_L2.0500.59
150_A211_W2.0480.59
27_R34_W2.0410.58
34_W131_Q2.0320.58
20_S219_I1.9910.56
126_I130_K1.8990.53
22_L29_V1.8580.51
124_S221_F1.8560.51
35_I70_L1.8310.50
114_L163_F1.7870.48
108_E166_P1.7870.48
28_E68_L1.7820.48
79_A118_I1.7110.45
164_L212_V1.6830.44
43_F126_I1.6690.43
76_L81_L1.6670.43
115_Y166_P1.6500.43
108_E214_W1.6470.43
111_V125_L1.6380.42
22_L30_D1.6350.42
91_N167_L1.6150.41
32_K197_K1.5440.39
87_L116_S1.5430.39
167_L197_K1.5360.38
87_L212_V1.5310.38
18_H22_L1.5070.37
93_S118_I1.4910.37
33_I149_S1.4770.36
104_V112_I1.4740.36
200_N203_K1.4720.36
29_V219_I1.4300.34
150_A213_A1.4130.34
79_A131_Q1.4120.34
59_S188_D1.4080.33
16_L213_A1.4050.33
84_N125_L1.3960.33
28_E127_N1.3940.33
82_F115_Y1.3770.32
122_I167_L1.3750.32
11_L26_Y1.3630.32
119_I139_P1.3480.31
24_L58_Y1.3460.31
174_G222_M1.3340.31
118_I162_K1.3330.31
115_Y124_S1.3260.31
78_G115_Y1.3230.30
128_F152_R1.3230.30
217_P233_G1.3230.30
14_I163_F1.3200.30
34_W83_L1.3170.30
34_W78_G1.3160.30
30_D35_I1.3040.30
45_I121_L1.2950.29
80_D217_P1.2930.29
82_F218_V1.2920.29
105_I194_L1.2690.29
41_C206_A1.2640.28
23_D29_V1.2630.28
87_L112_I1.2540.28
211_W219_I1.2500.28
39_P87_L1.2450.28
201_E204_I1.2370.28
64_N84_N1.2330.27
151_K226_Y1.2310.27
10_F145_L1.2220.27
16_L27_R1.2170.27
111_V223_L1.2160.27
126_I232_I1.2070.27
77_G80_D1.2060.27
17_I21_I1.2020.26
69_I204_I1.1950.26
15_M226_Y1.1950.26
150_A167_L1.1890.26
113_V220_P1.1820.26
83_L174_G1.1750.26
23_D80_D1.1650.25
64_N232_I1.1650.25
45_I58_Y1.1410.25
155_I208_T1.1280.24
42_L56_Y1.1250.24
200_N208_T1.1220.24
17_I37_Y1.1180.24
166_P214_W1.1140.24
30_D33_I1.1040.23
14_I183_S1.1010.23
158_F210_I1.0950.23
110_L212_V1.0900.23
41_C202_G1.0890.23
33_I152_R1.0880.23
16_L233_G1.0770.23
152_R214_W1.0770.23
62_I84_N1.0710.23
155_I210_I1.0690.22
36_Y164_L1.0670.22
15_M37_Y1.0670.22
110_L225_G1.0580.22
94_V168_T1.0470.22
59_S101_R1.0430.22
60_F79_A1.0400.22
116_S218_V1.0360.22
94_V101_R1.0360.22
40_L167_L1.0330.21
82_F108_E1.0280.21
81_L168_T1.0150.21
111_V118_I1.0060.21
17_I128_F1.0010.21
108_E124_S0.9990.21
108_E218_V0.9970.20
90_A108_E0.9920.20
164_L215_G0.9810.20
10_F14_I0.9810.20
114_L117_S0.9620.20
17_I110_L0.9610.20
61_I129_V0.9590.20
108_E131_Q0.9570.19
73_L112_I0.9550.19
36_Y79_A0.9530.19
87_L193_E0.9490.19
102_F157_D0.9430.19
89_L228_M0.9370.19
58_Y206_A0.9280.19
84_N149_S0.9270.19
18_H37_Y0.9270.19
153_I225_G0.9220.19
149_S227_I0.9200.19
76_L163_F0.9060.18
66_L222_M0.9040.18
117_S149_S0.9030.18
57_L132_Y0.9020.18
90_A167_L0.9010.18
71_Y219_I0.8920.18
116_S128_F0.8900.18
217_P225_G0.8810.18
29_V78_G0.8810.18
29_V86_I0.8770.17
82_F165_F0.8770.17
113_V168_T0.8740.17
31_P82_F0.8730.17
17_I223_L0.8710.17
89_L151_K0.8710.17
210_I229_S0.8710.17
111_V115_Y0.8700.17
115_Y131_Q0.8700.17
78_G152_R0.8680.17
41_C82_F0.8600.17
188_D212_V0.8510.17
48_F156_R0.8490.17
61_I231_I0.8470.17
20_S109_P0.8410.17
53_L231_I0.8280.16
111_V160_N0.8270.16
16_L20_S0.8220.16
17_I20_S0.8210.16
117_S139_P0.8130.16
48_F118_I0.8100.16
57_L60_F0.8070.16
151_K222_M0.8060.16
139_P152_R0.8060.16
111_V172_E0.8040.16
14_I156_R0.8030.16
48_F73_L0.8010.16
99_P224_A0.7960.16
93_S226_Y0.7930.16
11_L79_A0.7930.16
123_F151_K0.7910.16
91_N218_V0.7890.16
165_F232_I0.7870.15
102_F203_K0.7840.15
210_I218_V0.7790.15
29_V145_L0.7790.15
33_I148_L0.7780.15
35_I121_L0.7780.15
74_S81_L0.7760.15
12_S158_F0.7720.15
102_F193_E0.7650.15
27_R77_G0.7600.15
35_I212_V0.7600.15
125_L224_A0.7590.15
17_I73_L0.7560.15
101_R110_L0.7550.15
132_Y183_S0.7430.15
78_G82_F0.7360.14
77_G217_P0.7300.14
85_V181_Y0.7260.14
38_S86_I0.7250.14
82_F86_I0.7250.14
33_I74_S0.7240.14
74_S232_I0.7220.14
57_L227_I0.7200.14
61_I89_L0.7170.14
114_L219_I0.7140.14
80_D92_A0.7110.14
37_Y108_E0.7080.14
34_W76_L0.7070.14
81_L214_W0.7070.14
127_N145_L0.7000.14
70_L73_L0.6950.14
128_F189_K0.6950.14
16_L23_D0.6950.14
163_F170_V0.6910.14
149_S157_D0.6900.14
158_F228_M0.6850.13
167_L223_L0.6820.13
127_N221_F0.6800.13
76_L79_A0.6760.13
73_L89_L0.6760.13
33_I88_S0.6690.13
24_L61_I0.6650.13
26_Y120_I0.6630.13
115_Y225_G0.6620.13
41_C124_S0.6610.13
11_L156_R0.6580.13
109_P227_I0.6560.13
56_Y66_L0.6550.13
78_G131_Q0.6550.13
23_D217_P0.6550.13
66_L137_N0.6540.13
130_K151_K0.6530.13
16_L83_L0.6520.13
36_Y152_R0.6490.13
133_K177_M0.6430.13
10_F75_L0.6420.13
166_P191_W0.6410.13
16_L215_G0.6380.13
53_L204_I0.6300.12
61_I196_S0.6270.12
72_K85_V0.6260.12
17_I116_S0.6230.12
15_M230_L0.6230.12
27_R80_D0.6210.12
59_S62_I0.6210.12
44_I110_L0.6200.12
19_T23_D0.6200.12
89_L168_T0.6180.12
57_L88_S0.6180.12
118_I231_I0.6170.12
134_Y162_K0.6150.12
53_L219_I0.6120.12
13_I208_T0.6110.12
161_S213_A0.6100.12
65_L71_Y0.6070.12
91_N195_Y0.6060.12
65_L186_E0.6040.12
121_L148_L0.6020.12
19_T54_P0.6010.12
85_V154_K0.6000.12
20_S220_P0.5970.12
108_E195_Y0.5940.12
28_E78_G0.5930.12
78_G125_L0.5920.12
23_D77_G0.5820.12
114_L196_S0.5810.12
62_I185_E0.5790.12
25_K208_T0.5790.12
75_L165_F0.5790.12
68_L106_G0.5780.12
25_K206_A0.5780.12
139_P207_D0.5780.12
118_I226_Y0.5780.12
19_T219_I0.5750.11
26_Y46_F0.5740.11
59_S120_I0.5740.11
87_L163_F0.5720.11
22_L28_E0.5710.11
164_L192_R0.5710.11
214_W221_F0.5690.11
62_I160_N0.5690.11
40_L79_A0.5640.11
59_S185_E0.5640.11
68_L137_N0.5630.11
28_E76_L0.5620.11
76_L144_I0.5620.11
36_Y42_L0.5600.11
129_V230_L0.5600.11
91_N132_Y0.5590.11
70_L83_L0.5540.11
77_G211_W0.5510.11
29_V53_L0.5500.11
31_P229_S0.5440.11
18_H28_E0.5430.11
98_V152_R0.5400.11
14_I28_E0.5390.11
79_A86_I0.5380.11
166_P210_I0.5370.11
20_S139_P0.5350.11
184_V194_L0.5350.11
81_L124_S0.5350.11
12_S226_Y0.5300.11
57_L91_N0.5280.11
87_L126_I0.5270.11
218_V230_L0.5260.11
116_S203_K0.5250.11
46_F82_F0.5230.11
190_Y196_S0.5210.11
29_V81_L0.5200.11
53_L121_L0.5180.11
51_L70_L0.5180.11
42_L47_S0.5170.11
68_L196_S0.5140.11
63_T208_T0.5120.10
91_N134_Y0.5120.10
67_F156_R0.5100.10
181_Y185_E0.5090.10
43_F122_I0.5040.10
16_L211_W0.5030.10
12_S69_I0.5030.10
58_Y149_S0.5020.10
82_F124_S0.5000.10
131_Q150_A0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3s0xA 1 0.9025 100 0.446 Contact Map
1p1xA 1 0.3008 10.9 0.962 Contact Map
4cbcA 3 0.3305 9.4 0.964 Contact Map
4mh8A 1 0.3771 6.5 0.966 Contact Map
4g1qB 2 0.3263 5.9 0.967 Contact Map
4ltoA 3 0.5212 5.8 0.967 Contact Map
1mu2A 2 0.3136 5.7 0.967 Contact Map
4xpcA 1 0.3771 4.4 0.969 Contact Map
4g1qA 2 0.3347 4.1 0.969 Contact Map
4hr6A 1 0.1737 3.1 0.971 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0082 seconds.