GREMLIN Database
RS8E - 30S ribosomal protein S8e
UniProt: Q980W3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 133 (108)
Sequences: 397 (234)
Seq/√Len: 22.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
11_K15_G6.9271.00
80_E94_G4.8501.00
63_A102_I3.5931.00
48_T52_N2.7690.99
63_A109_A2.7630.99
25_K28_I2.6290.99
67_D70_T2.4910.98
76_V105_E2.3210.97
83_E91_A2.1900.96
3_F28_I2.1350.95
74_K77_K2.1270.95
45_K55_V2.0600.94
77_K105_E1.9440.92
37_L43_R1.8260.89
85_P97_I1.8000.89
98_R101_K1.7230.86
66_L73_A1.6880.85
47_R52_N1.6430.84
65_V106_A1.6180.83
62_T77_K1.5840.81
92_R97_I1.5420.79
104_T107_G1.4910.77
33_T56_R1.4460.75
82_L108_L1.4250.74
21_R24_R1.4170.73
29_G35_T1.3680.71
26_Y49_L1.3550.70
61_T77_K1.3440.69
102_I109_A1.3290.68
4_Y27_E1.2750.65
84_T97_I1.2440.63
88_K91_A1.2260.62
10_R78_I1.1640.58
76_V106_A1.1500.57
60_T96_I1.1490.57
7_P12_I1.1180.55
40_E61_T1.1110.54
48_T53_F1.1060.54
12_I15_G1.0820.52
7_P31_P1.0680.51
103_R108_L1.0590.51
50_G109_A1.0560.50
4_Y33_T1.0450.50
39_A61_T1.0320.49
83_E88_K1.0290.49
15_G20_H1.0260.48
5_Q23_K1.0210.48
37_L78_I1.0030.47
5_Q8_D0.9910.46
56_R92_R0.9900.46
84_T91_A0.9850.46
31_P89_E0.9750.45
47_R51_G0.9620.44
4_Y8_D0.9580.44
42_I88_K0.9450.43
22_D30_N0.9320.42
30_N46_D0.9290.42
15_G74_K0.9150.41
70_T106_A0.9140.41
20_H31_P0.9110.41
86_A109_A0.9080.40
97_I102_I0.9000.40
10_R13_T0.8980.40
57_L72_T0.8750.38
74_K101_K0.8650.38
32_P35_T0.8440.36
73_A96_I0.8440.36
27_E64_N0.8370.36
94_G104_T0.8360.36
38_S42_I0.8290.35
25_K64_N0.8160.34
30_N33_T0.8060.34
57_L64_N0.8010.34
9_N60_T0.7950.33
8_D84_T0.7850.33
46_D56_R0.7750.32
29_G109_A0.7730.32
94_G99_G0.7730.32
58_K73_A0.7540.31
7_P17_K0.7530.31
24_R35_T0.7410.30
52_N102_I0.7390.30
29_G57_L0.7350.30
33_T46_D0.7350.30
68_P103_R0.7290.29
12_I69_A0.7160.29
66_L85_P0.7160.29
32_P54_K0.7080.28
9_N59_Y0.7070.28
93_R104_T0.7030.28
75_K105_E0.6970.28
9_N17_K0.6970.28
41_D59_Y0.6940.27
92_R98_R0.6920.27
21_R28_I0.6910.27
91_A94_G0.6890.27
40_E60_T0.6890.27
67_D106_A0.6850.27
24_R27_E0.6810.27
5_Q30_N0.6750.26
4_Y7_P0.6740.26
36_T95_I0.6710.26
23_K29_G0.6680.26
3_F29_G0.6610.26
99_G107_G0.6510.25
71_N86_A0.6480.25
8_D94_G0.6470.25
51_G78_I0.6460.25
87_N107_G0.6460.25
16_L70_T0.6430.25
74_K105_E0.6420.25
82_L92_R0.6260.24
26_Y82_L0.6260.24
76_V101_K0.6180.23
21_R26_Y0.6170.23
62_T75_K0.6170.23
86_A102_I0.6070.23
93_R107_G0.6050.23
34_F90_L0.6000.23
20_H45_K0.5990.22
16_L67_D0.5990.22
23_K31_P0.5960.22
80_E103_R0.5900.22
73_A81_I0.5890.22
79_L103_R0.5850.22
83_E93_R0.5830.22
31_P99_G0.5830.22
15_G77_K0.5830.22
68_P106_A0.5820.22
19_K40_E0.5780.21
45_K62_T0.5750.21
37_L81_I0.5630.21
39_A76_V0.5600.21
7_P18_G0.5600.21
43_R64_N0.5540.20
3_F22_D0.5540.20
90_L93_R0.5520.20
4_Y65_V0.5510.20
97_I100_A0.5510.20
9_N22_D0.5480.20
38_S61_T0.5470.20
6_G10_R0.5470.20
43_R46_D0.5450.20
20_H71_N0.5440.20
10_R23_K0.5430.20
30_N49_L0.5410.20
84_T99_G0.5360.20
64_N84_T0.5310.19
6_G109_A0.5300.19
35_T57_L0.5250.19
31_P95_I0.5230.19
35_T95_I0.5190.19
30_N84_T0.5170.19
16_L56_R0.5160.19
58_K94_G0.5110.19
86_A100_A0.5100.19
98_R108_L0.5090.18
26_Y73_A0.5040.18
9_N12_I0.5020.18
77_K82_L0.5020.18
21_R27_E0.5000.18
50_G54_K0.5000.18
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2kcoA 1 0.9925 100 0.064 Contact Map
4ujpJ 1 0.985 100 0.089 Contact Map
3j20J 1 0.9474 100 0.091 Contact Map
4bpe2 1 0.985 100 0.112 Contact Map
3j60I 1 0.1955 100 0.117 Contact Map
3j7aL 1 0.9699 100 0.137 Contact Map
4w23I 1 0.985 100 0.142 Contact Map
3j38I 1 0.985 100 0.142 Contact Map
3zey5 1 0.985 100 0.148 Contact Map
2kcpA 1 0.7143 100 0.34 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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