DNLI - SULSO - GREMLIN Contacts

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DNLI - DNA ligase

UniProt:	Q980T8	Sequences: MEFKVIAEYFDKLEKISSRLQLTALLADLLSKSDKTIIDKVVYIIQGKLWPDFLGYPELGIGEKFLIKAISIATNTDENSVENLYKTIGDLGEVARRLKSKQQSTGILGFLGTTSKESLTVDEVYSTLSKVALTTGEGSRDLKIRLLAGLLKKADPLEAKFLVRFVEGRLRVGIGDATVLDAMAIAFGGGQSASEIIERAYNLRADLGNIAKIIVEKGIEALKTLKPQVGIPIRPMLAERLSNPEEILKKMGGNAIVDYKYDGERAQIHKKEDKIFIFSRRLENITSQYPDVVDYVSKYIEGKEFIIEGEIVAIDPESGEMRPFQELMHRKRKSDIYEAIKEYPVNVFLFDLMYYEDVDYTTKPLEARRKLLESIVKPNDYVKIAHHIQANNVEDLKSFFYRAISEGGEGVMVKAIGKDAIYQAGARGWLWIKLKRDYQSEMADTVDLVVVGGFYGKGKRGGKISSLLMAAYNPKTDSFESVCKVASGFSDEQLDELQKKLMEIKRDVKHPRVNSKMEPDIWVEPVYVAEIIGSEITISPLHTCCQDVVEKDAGLSIRFPRFIRWRDDKSPEDATTTDEILEMYNKQPKKKIESPAVDESV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	601 (536)
Sequences:	1821 (1187)
Seq/√Len:	51.3

HALSA - DNLI
SULSO - DNLI

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
451_V	470_A	8.380	1.00
363_K	367_A	7.949	1.00
358_V	363_K	5.113	1.00
473_N	480_E	4.976	1.00
276_F	284_N	4.478	1.00
304_E	357_D	4.472	1.00
367_A	370_K	4.378	1.00
575_T	579_E	4.364	1.00
570_S	573_D	4.242	1.00
355_Y	371_L	3.858	1.00
268_I	347_V	3.851	1.00
448_L	471_A	3.832	1.00
256_I	365_L	3.813	1.00
26_L	30_L	3.637	1.00
155_D	158_E	3.504	1.00
451_V	481_S	3.082	1.00
352_L	371_L	3.011	1.00
504_I	524_E	2.992	1.00
18_S	21_Q	2.986	1.00
257_V	396_L	2.945	1.00
453_G	464_I	2.859	1.00
72_I	144_I	2.772	1.00
150_L	162_L	2.657	1.00
402_R	406_E	2.650	1.00
504_I	526_V	2.634	1.00
268_I	277_I	2.562	1.00
446_V	580_I	2.506	1.00
474_P	477_D	2.486	1.00
90_D	164_R	2.468	1.00
358_V	371_L	2.460	1.00
307_I	349_L	2.429	1.00
326_E	329_H	2.377	1.00
6_I	10_F	2.330	1.00
364_P	367_A	2.269	1.00
275_I	293_V	2.253	1.00
376_V	382_V	2.245	1.00
370_K	374_S	2.234	1.00
473_N	476_T	2.211	1.00
76_T	98_L	2.211	1.00
261_Y	385_A	2.199	1.00
415_A	419_D	2.197	1.00
499_K	503_E	2.192	1.00
392_N	395_D	2.161	1.00
309_G	347_V	2.152	1.00
397_K	401_Y	2.151	1.00
5_V	32_K	2.125	1.00
322_R	326_E	2.122	1.00
388_I	399_F	2.101	1.00
490_S	493_Q	2.094	1.00
496_E	567_D	2.079	1.00
373_E	384_I	2.072	1.00
266_A	277_I	2.067	1.00
472_Y	574_A	2.067	1.00
391_N	395_D	2.058	1.00
395_D	398_S	2.039	1.00
465_S	494_L	2.002	1.00
480_E	577_T	2.001	1.00
566_R	569_K	1.990	1.00
352_L	375_I	1.984	1.00
125_Y	129_S	1.979	1.00
515_S	522_W	1.972	1.00
558_R	561_R	1.961	1.00
9_Y	13_L	1.954	1.00
303_K	356_E	1.949	0.99
119_L	124_V	1.882	0.99
313_A	322_R	1.881	0.99
532_I	563_I	1.880	0.99
482_V	580_I	1.877	0.99
34_D	37_I	1.875	0.99
16_I	21_Q	1.859	0.99
66_L	95_A	1.852	0.99
373_E	387_H	1.847	0.99
450_V	501_L	1.828	0.99
123_E	153_K	1.824	0.99
23_T	178_T	1.811	0.99
363_K	371_L	1.808	0.99
338_E	342_E	1.807	0.99
286_T	293_V	1.790	0.99
445_T	530_E	1.783	0.99
21_Q	24_A	1.781	0.99
27_A	185_I	1.779	0.99
467_L	501_L	1.750	0.99
459_K	487_S	1.729	0.99
141_D	145_R	1.693	0.99
271_K	274_K	1.680	0.98
536_I	555_L	1.676	0.98
533_G	557_I	1.673	0.98
294_D	298_K	1.671	0.98
479_F	571_P	1.661	0.98
9_Y	29_L	1.650	0.98
270_K	275_I	1.627	0.98
151_L	163_V	1.625	0.98
474_P	578_D	1.605	0.98
28_D	32_K	1.605	0.98
292_V	347_V	1.602	0.98
70_I	95_A	1.591	0.98
538_I	581_L	1.591	0.98
470_A	479_F	1.586	0.98
301_E	377_K	1.581	0.98
154_A	162_L	1.572	0.98
42_V	179_V	1.571	0.98
27_A	31_S	1.552	0.97
307_I	347_V	1.547	0.97
459_K	491_D	1.541	0.97
257_V	413_V	1.538	0.97
352_L	355_Y	1.538	0.97
466_S	486_A	1.536	0.97
369_R	373_E	1.525	0.97
205_A	210_I	1.501	0.97
20_L	23_T	1.496	0.97
257_V	390_A	1.488	0.97
271_K	304_E	1.469	0.96
449_V	528_V	1.466	0.96
402_R	405_S	1.461	0.96
24_A	28_D	1.455	0.96
91_L	457_K	1.452	0.96
197_I	200_A	1.443	0.96
272_E	303_K	1.441	0.96
371_L	374_S	1.420	0.96
257_V	411_V	1.413	0.95
460_R	486_A	1.413	0.95
498_Q	502_M	1.402	0.95
576_T	579_E	1.397	0.95
127_T	146_L	1.397	0.95
534_S	537_T	1.393	0.95
365_L	420_A	1.392	0.95
72_I	148_A	1.376	0.95
454_F	468_L	1.375	0.95
251_M	254_N	1.373	0.95
437_D	534_S	1.354	0.94
445_T	532_I	1.352	0.94
474_P	576_T	1.349	0.94
450_V	529_A	1.327	0.94
275_I	300_I	1.325	0.94
264_E	289_Y	1.324	0.94
70_I	98_L	1.324	0.94
530_E	564_R	1.320	0.94
423_Q	430_L	1.320	0.94
207_L	210_I	1.320	0.94
84_L	94_V	1.313	0.93
7_A	158_E	1.312	0.93
449_V	574_A	1.312	0.93
314_I	319_G	1.301	0.93
445_T	563_I	1.289	0.93
245_E	249_K	1.288	0.93
16_I	25_L	1.287	0.93
555_L	584_Y	1.286	0.93
208_G	212_K	1.284	0.93
91_L	163_V	1.281	0.92
466_S	485_V	1.279	0.92
477_D	572_E	1.271	0.92
316_P	319_G	1.270	0.92
582_E	586_K	1.268	0.92
312_V	321_M	1.268	0.92
212_K	216_E	1.263	0.92
315_D	318_S	1.262	0.92
119_L	123_E	1.259	0.92
249_K	397_K	1.257	0.92
24_A	185_I	1.248	0.91
420_A	431_W	1.246	0.91
366_E	419_D	1.242	0.91
120_T	123_E	1.242	0.91
522_W	525_P	1.232	0.91
9_Y	25_L	1.227	0.91
67_I	78_E	1.225	0.91
365_L	387_H	1.221	0.91
349_L	352_L	1.217	0.90
327_L	345_V	1.206	0.90
13_L	22_L	1.204	0.90
517_M	542_H	1.203	0.90
131_V	166_V	1.197	0.90
275_I	296_V	1.195	0.90
50_W	56_Y	1.192	0.89
313_A	343_Y	1.192	0.89
259_Y	408_G	1.192	0.89
492_E	495_D	1.184	0.89
247_I	413_V	1.178	0.89
494_L	562_F	1.176	0.89
256_I	387_H	1.173	0.89
68_K	72_I	1.172	0.89
25_L	28_D	1.164	0.88
349_L	382_V	1.162	0.88
497_L	500_K	1.160	0.88
240_R	268_I	1.157	0.88
396_L	413_V	1.156	0.88
93_E	97_R	1.154	0.88
85_Y	457_K	1.147	0.88
390_A	395_D	1.143	0.87
346_N	383_K	1.142	0.87
538_I	553_A	1.139	0.87
324_F	329_H	1.138	0.87
404_I	444_D	1.137	0.87
420_A	481_S	1.137	0.87
134_T	146_L	1.131	0.87
230_G	236_M	1.130	0.87
354_Y	357_D	1.128	0.87
249_K	254_N	1.124	0.86
290_P	330_R	1.124	0.86
6_I	165_F	1.122	0.86
167_E	457_K	1.121	0.86
482_V	557_I	1.120	0.86
396_L	399_F	1.119	0.86
437_D	561_R	1.114	0.86
12_K	28_D	1.114	0.86
316_P	380_D	1.111	0.86
482_V	497_L	1.109	0.86
48_K	52_D	1.109	0.86
569_K	573_D	1.105	0.86
270_K	273_D	1.102	0.85
314_I	346_N	1.099	0.85
324_F	330_R	1.098	0.85
438_Y	448_L	1.088	0.85
460_R	487_S	1.086	0.85
388_I	411_V	1.086	0.85
528_V	571_P	1.083	0.84
16_I	20_L	1.083	0.84
312_V	348_F	1.082	0.84
237_L	280_R	1.081	0.84
280_R	488_G	1.074	0.84
211_A	214_I	1.069	0.84
481_S	542_H	1.069	0.84
124_V	150_L	1.068	0.84
444_D	534_S	1.068	0.84
80_S	83_N	1.067	0.83
27_A	187_F	1.062	0.83
245_E	248_L	1.060	0.83
495_D	499_K	1.059	0.83
473_N	478_S	1.058	0.83
247_I	250_K	1.058	0.83
211_A	215_V	1.055	0.83
526_V	571_P	1.047	0.82
5_V	8_E	1.045	0.82
320_E	407_G	1.044	0.82
233_I	536_I	1.044	0.82
582_E	585_N	1.039	0.82
192_S	195_E	1.039	0.82
200_A	210_I	1.034	0.81
468_L	481_S	1.034	0.81
259_Y	406_E	1.032	0.81
446_V	524_E	1.029	0.81
456_G	468_L	1.028	0.81
191_Q	195_E	1.026	0.81
266_A	311_I	1.025	0.81
400_F	411_V	1.022	0.81
204_R	209_N	1.021	0.81
11_D	157_L	1.018	0.80
456_G	460_R	1.013	0.80
160_K	278_F	1.007	0.80
409_E	433_K	0.998	0.79
184_A	277_I	0.997	0.79
127_T	130_K	0.997	0.79
486_A	493_Q	0.995	0.79
414_K	447_D	0.988	0.78
312_V	437_D	0.986	0.78
525_P	554_G	0.985	0.78
562_F	565_W	0.984	0.78
436_R	444_D	0.981	0.78
528_V	574_A	0.980	0.78
539_S	542_H	0.978	0.78
539_S	558_R	0.971	0.77
93_E	96_R	0.971	0.77
268_I	311_I	0.969	0.77
348_F	383_K	0.968	0.77
51_P	147_L	0.968	0.77
386_H	402_R	0.968	0.77
226_K	277_I	0.966	0.77
460_R	465_S	0.963	0.77
539_S	554_G	0.961	0.76
555_L	581_L	0.960	0.76
388_I	402_R	0.959	0.76
330_R	333_K	0.959	0.76
324_F	327_L	0.958	0.76
291_D	330_R	0.957	0.76
315_D	322_R	0.957	0.76
444_D	536_I	0.957	0.76
473_N	477_D	0.956	0.76
268_I	275_I	0.954	0.76
268_I	296_V	0.952	0.76
271_K	354_Y	0.948	0.75
85_Y	91_L	0.945	0.75
67_I	91_L	0.945	0.75
33_S	37_I	0.944	0.75
93_E	460_R	0.943	0.75
579_E	583_M	0.942	0.75
465_S	487_S	0.942	0.75
39_D	44_I	0.940	0.75
202_N	206_D	0.939	0.75
469_M	485_V	0.934	0.74
316_P	364_P	0.932	0.74
539_S	561_R	0.932	0.74
472_Y	479_F	0.930	0.74
29_L	41_V	0.930	0.74
7_A	10_F	0.929	0.74
506_R	522_W	0.927	0.74
455_Y	521_I	0.921	0.73
191_Q	196_I	0.920	0.73
46_Q	176_D	0.919	0.73
131_V	146_L	0.918	0.73
500_K	527_Y	0.916	0.73
280_R	566_R	0.913	0.73
539_S	559_F	0.909	0.72
209_N	213_I	0.908	0.72
493_Q	496_E	0.908	0.72
227_P	337_Y	0.905	0.72
13_L	174_I	0.903	0.72
224_T	268_I	0.901	0.72
230_G	276_F	0.900	0.72
28_D	31_S	0.895	0.71
131_V	143_K	0.891	0.71
167_E	233_I	0.888	0.71
465_S	486_A	0.884	0.70
305_F	355_Y	0.884	0.70
305_F	376_V	0.883	0.70
30_L	223_K	0.876	0.70
454_F	519_P	0.875	0.69
319_G	383_K	0.872	0.69
249_K	253_G	0.862	0.68
266_A	347_V	0.862	0.68
328_M	331_K	0.862	0.68
354_Y	359_D	0.861	0.68
24_A	223_K	0.860	0.68
183_M	214_I	0.860	0.68
201_Y	306_I	0.860	0.68
438_Y	534_S	0.857	0.68
303_K	357_D	0.856	0.68
292_V	296_V	0.856	0.68
134_T	402_R	0.855	0.68
313_A	345_V	0.854	0.68
315_D	320_E	0.852	0.67
127_T	153_K	0.852	0.67
120_T	377_K	0.850	0.67
314_I	321_M	0.849	0.67
318_S	321_M	0.846	0.67
334_S	339_A	0.843	0.67
70_I	81_V	0.843	0.67
148_A	166_V	0.839	0.66
122_D	126_S	0.836	0.66
313_A	399_F	0.836	0.66
381_Y	395_D	0.835	0.66
248_L	252_G	0.834	0.66
338_E	341_K	0.829	0.65
349_L	376_V	0.827	0.65
89_G	458_G	0.821	0.64
378_P	386_H	0.818	0.64
454_F	520_D	0.816	0.64
403_A	436_R	0.812	0.64
289_Y	328_M	0.811	0.64
489_F	501_L	0.809	0.63
454_F	484_K	0.805	0.63
67_I	82_E	0.804	0.63
267_Q	559_F	0.803	0.63
378_P	383_K	0.802	0.63
484_K	569_K	0.801	0.63
295_Y	374_S	0.800	0.62
454_F	466_S	0.800	0.62
481_S	543_T	0.797	0.62
207_L	211_A	0.795	0.62
542_H	556_S	0.795	0.62
400_F	436_R	0.792	0.62
8_E	15_K	0.791	0.62
9_Y	565_W	0.790	0.61
96_R	100_S	0.789	0.61
6_I	121_V	0.786	0.61
45_I	557_I	0.786	0.61
265_R	488_G	0.783	0.61
6_I	29_L	0.782	0.61
400_F	434_L	0.781	0.61
486_A	517_M	0.780	0.60
258_D	369_R	0.778	0.60
130_K	146_L	0.777	0.60
496_E	500_K	0.777	0.60
236_M	542_H	0.776	0.60
296_V	386_H	0.775	0.60
370_K	373_E	0.775	0.60
121_V	125_Y	0.775	0.60
10_F	17_S	0.774	0.60
454_F	486_A	0.774	0.60
521_I	542_H	0.771	0.60
324_F	530_E	0.769	0.59
326_E	343_Y	0.768	0.59
376_V	384_I	0.768	0.59
296_V	347_V	0.768	0.59
204_R	210_I	0.767	0.59
69_A	73_A	0.766	0.59
121_V	124_V	0.766	0.59
327_L	330_R	0.765	0.59
67_I	81_V	0.765	0.59
23_T	181_D	0.764	0.59
240_R	434_L	0.763	0.59
310_E	409_E	0.762	0.59
217_K	224_T	0.762	0.59
158_E	286_T	0.761	0.59
8_E	364_P	0.760	0.58
452_G	468_L	0.758	0.58
307_I	450_V	0.757	0.58
10_F	15_K	0.757	0.58
238_A	456_G	0.756	0.58
124_V	495_D	0.756	0.58
233_I	353_M	0.755	0.58
171_R	458_G	0.755	0.58
528_V	569_K	0.754	0.58
44_I	47_G	0.754	0.58
538_I	584_Y	0.752	0.58
124_V	376_V	0.751	0.58
283_E	330_R	0.751	0.58
69_A	228_Q	0.750	0.57
409_E	435_K	0.750	0.57
310_E	433_K	0.750	0.57
329_H	343_Y	0.749	0.57
117_E	153_K	0.748	0.57
12_K	25_L	0.748	0.57
73_A	147_L	0.747	0.57
260_K	310_E	0.746	0.57
23_T	185_I	0.746	0.57
484_K	491_D	0.745	0.57
136_G	143_K	0.745	0.57
370_K	411_V	0.744	0.57
238_A	412_M	0.742	0.57
280_R	456_G	0.741	0.57
83_N	314_I	0.741	0.57
44_I	165_F	0.740	0.56
73_A	152_K	0.740	0.56
260_K	414_K	0.740	0.56
169_R	457_K	0.737	0.56
179_V	182_A	0.736	0.56
142_L	145_R	0.735	0.56
365_L	412_M	0.733	0.56
349_L	535_E	0.732	0.56
64_K	407_G	0.731	0.56
489_F	494_L	0.731	0.56
103_Q	459_K	0.728	0.55
38_I	43_Y	0.728	0.55
127_T	149_G	0.727	0.55
77_D	83_N	0.726	0.55
132_A	136_G	0.726	0.55
8_E	130_K	0.723	0.55
485_V	517_M	0.723	0.55
264_E	328_M	0.723	0.55
273_D	303_K	0.723	0.55
388_I	392_N	0.723	0.55
71_S	81_V	0.723	0.55
237_L	488_G	0.722	0.55
346_N	381_Y	0.721	0.55
352_L	360_Y	0.718	0.54
364_P	531_I	0.718	0.54
245_E	393_V	0.718	0.54
492_E	496_E	0.718	0.54
500_K	504_I	0.718	0.54
89_G	171_R	0.717	0.54
170_L	304_E	0.716	0.54
267_Q	279_S	0.716	0.54
288_Q	345_V	0.715	0.54
266_A	292_V	0.715	0.54
75_N	126_S	0.715	0.54
489_F	562_F	0.714	0.54
312_V	345_V	0.714	0.54
456_G	484_K	0.713	0.54
415_A	430_L	0.712	0.54
325_Q	537_T	0.711	0.53
319_G	379_N	0.707	0.53
145_R	148_A	0.707	0.53
183_M	186_A	0.706	0.53
536_I	584_Y	0.706	0.53
367_A	371_L	0.705	0.53
390_A	396_L	0.705	0.53
534_S	561_R	0.704	0.53
431_W	569_K	0.703	0.53
470_A	572_E	0.699	0.52
260_K	409_E	0.698	0.52
398_S	573_D	0.698	0.52
533_G	536_I	0.698	0.52
500_K	536_I	0.696	0.52
201_Y	207_L	0.696	0.52
285_I	288_Q	0.694	0.52
458_G	554_G	0.693	0.52
149_G	524_E	0.691	0.51
437_D	533_G	0.691	0.51
120_T	147_L	0.688	0.51
554_G	566_R	0.687	0.51
260_K	433_K	0.686	0.51
329_H	411_V	0.685	0.51
121_V	296_V	0.684	0.51
65_F	396_L	0.681	0.50
86_K	394_E	0.680	0.50
27_A	186_A	0.680	0.50
239_E	430_L	0.680	0.50
362_T	421_I	0.679	0.50
84_L	97_R	0.678	0.50
71_S	78_E	0.677	0.50
43_Y	183_M	0.677	0.50
360_Y	371_L	0.677	0.50
92_G	160_K	0.676	0.50
206_D	211_A	0.676	0.50
123_E	499_K	0.676	0.50
70_I	159_A	0.675	0.50
63_E	289_Y	0.674	0.50
144_I	148_A	0.674	0.50
229_V	271_K	0.674	0.50
196_I	306_I	0.672	0.49
64_K	557_I	0.670	0.49
450_V	562_F	0.668	0.49
384_I	399_F	0.666	0.49
124_V	360_Y	0.666	0.49
104_S	115_S	0.666	0.49
363_K	370_K	0.665	0.49
266_A	312_V	0.664	0.49
23_T	213_I	0.664	0.49
367_A	401_Y	0.664	0.49
498_Q	501_L	0.664	0.49
306_I	354_Y	0.662	0.48
85_Y	88_I	0.662	0.48
192_S	196_I	0.661	0.48
484_K	561_R	0.660	0.48
167_E	556_S	0.658	0.48
247_I	356_E	0.658	0.48
261_Y	444_D	0.658	0.48
53_F	92_G	0.657	0.48
325_Q	444_D	0.657	0.48
128_L	167_E	0.654	0.48
72_I	221_A	0.653	0.47
22_L	174_I	0.652	0.47
96_R	160_K	0.650	0.47
8_E	12_K	0.650	0.47
362_T	391_N	0.648	0.47
297_S	384_I	0.647	0.47
484_K	517_M	0.646	0.47
147_L	166_V	0.645	0.47
238_A	403_A	0.645	0.47
365_L	369_R	0.644	0.47
453_G	518_E	0.643	0.46
295_Y	311_I	0.641	0.46
259_Y	327_L	0.641	0.46
124_V	128_L	0.640	0.46
298_K	377_K	0.640	0.46
88_I	93_E	0.639	0.46
51_P	62_G	0.639	0.46
274_K	303_K	0.639	0.46
126_S	130_K	0.638	0.46
238_A	460_R	0.637	0.46
11_D	14_E	0.636	0.46
39_D	212_K	0.636	0.46
199_R	221_A	0.635	0.46
66_L	167_E	0.635	0.46
212_K	413_V	0.633	0.45
232_P	333_K	0.633	0.45
362_T	370_K	0.632	0.45
173_G	237_L	0.631	0.45
263_G	435_K	0.631	0.45
358_V	478_S	0.630	0.45
280_R	308_E	0.630	0.45
20_L	540_P	0.629	0.45
462_G	520_D	0.628	0.45
234_R	282_L	0.628	0.45
265_R	308_E	0.627	0.45
335_D	338_E	0.627	0.45
176_D	353_M	0.627	0.45
149_G	496_E	0.626	0.45
469_M	521_I	0.626	0.45
275_I	292_V	0.625	0.45
233_I	556_S	0.625	0.45
5_V	29_L	0.624	0.44
363_K	379_N	0.623	0.44
154_A	158_E	0.623	0.44
37_I	467_L	0.623	0.44
15_K	24_A	0.621	0.44
11_D	15_K	0.621	0.44
238_A	265_R	0.620	0.44
53_F	61_I	0.620	0.44
260_K	447_D	0.620	0.44
456_G	486_A	0.618	0.44
400_F	438_Y	0.618	0.44
536_I	557_I	0.618	0.44
254_N	419_D	0.617	0.44
167_E	264_E	0.617	0.44
269_H	306_I	0.617	0.44
232_P	456_G	0.616	0.44
357_D	360_Y	0.616	0.44
153_K	306_I	0.616	0.44
69_A	470_A	0.614	0.43
208_G	473_N	0.614	0.43
82_E	86_K	0.613	0.43
237_L	308_E	0.613	0.43
224_T	229_V	0.612	0.43
471_A	536_I	0.611	0.43
485_V	533_G	0.610	0.43
468_L	486_A	0.610	0.43
375_I	379_N	0.608	0.43
6_I	470_A	0.608	0.43
455_Y	464_I	0.608	0.43
499_K	502_M	0.608	0.43
232_P	330_R	0.607	0.43
78_E	82_E	0.607	0.43
296_V	382_V	0.605	0.43
90_D	332_R	0.604	0.42
236_M	494_L	0.604	0.42
399_F	411_V	0.603	0.42
13_L	404_I	0.602	0.42
426_A	429_W	0.602	0.42
239_E	429_W	0.602	0.42
438_Y	452_G	0.602	0.42
486_A	520_D	0.601	0.42
237_L	566_R	0.601	0.42
146_L	162_L	0.600	0.42
92_G	159_A	0.600	0.42
263_G	409_E	0.600	0.42
398_S	402_R	0.600	0.42
364_P	403_A	0.599	0.42
227_P	565_W	0.598	0.42
70_I	74_T	0.597	0.42
8_E	294_D	0.596	0.42
471_A	580_I	0.596	0.42
256_I	389_Q	0.595	0.42
71_S	82_E	0.594	0.41
165_F	247_I	0.594	0.41
327_L	574_A	0.594	0.41
241_L	244_P	0.593	0.41
240_R	579_E	0.590	0.41
312_V	453_G	0.590	0.41
99_K	102_Q	0.590	0.41
187_F	214_I	0.589	0.41
263_G	433_K	0.588	0.41
242_S	246_E	0.588	0.41
280_R	427_R	0.587	0.41
79_N	83_N	0.587	0.41
505_K	521_I	0.586	0.41
578_D	581_L	0.586	0.41
280_R	458_G	0.585	0.41
288_Q	529_A	0.585	0.41
227_P	538_I	0.583	0.40
395_D	399_F	0.582	0.40
337_Y	341_K	0.581	0.40
525_P	536_I	0.580	0.40
32_K	296_V	0.580	0.40
73_A	95_A	0.580	0.40
50_W	53_F	0.579	0.40
89_G	558_R	0.578	0.40
467_L	529_A	0.577	0.40
30_L	423_Q	0.576	0.40
70_I	362_T	0.576	0.40
158_E	557_I	0.575	0.40
61_I	162_L	0.574	0.39
96_R	353_M	0.574	0.39
243_N	247_I	0.573	0.39
119_L	427_R	0.572	0.39
329_H	339_A	0.572	0.39
530_E	569_K	0.572	0.39
232_P	237_L	0.572	0.39
369_R	387_H	0.571	0.39
483_C	556_S	0.571	0.39
193_A	196_I	0.570	0.39
8_E	104_S	0.568	0.39
500_K	526_V	0.568	0.39
260_K	263_G	0.567	0.39
386_H	399_F	0.567	0.39
127_T	578_D	0.567	0.39
334_S	524_E	0.567	0.39
279_S	343_Y	0.566	0.39
277_I	293_V	0.565	0.39
449_V	493_Q	0.564	0.38
191_Q	194_S	0.564	0.38
427_R	567_D	0.563	0.38
45_I	146_L	0.563	0.38
7_A	157_L	0.562	0.38
558_R	580_I	0.562	0.38
446_V	471_A	0.561	0.38
336_I	339_A	0.561	0.38
309_G	349_L	0.561	0.38
214_I	217_K	0.561	0.38
291_D	345_V	0.559	0.38
463_K	495_D	0.559	0.38
252_G	307_I	0.557	0.38
273_D	307_I	0.557	0.38
247_I	251_M	0.557	0.38
88_I	506_R	0.556	0.38
213_I	217_K	0.556	0.38
70_I	128_L	0.555	0.38
171_R	182_A	0.554	0.37
95_A	121_V	0.554	0.37
492_E	570_S	0.554	0.37
256_I	369_R	0.554	0.37
517_M	543_T	0.554	0.37
17_S	576_T	0.553	0.37
311_I	327_L	0.552	0.37
308_E	420_A	0.552	0.37
460_R	554_G	0.552	0.37
130_K	135_T	0.552	0.37
258_D	414_K	0.551	0.37
217_K	221_A	0.550	0.37
43_Y	125_Y	0.548	0.37
425_G	553_A	0.547	0.37
362_T	378_P	0.547	0.37
72_I	383_K	0.546	0.37
264_E	466_S	0.546	0.37
573_D	577_T	0.546	0.37
183_M	578_D	0.545	0.37
13_L	26_L	0.545	0.37
262_D	414_K	0.545	0.37
168_G	466_S	0.545	0.37
200_A	207_L	0.544	0.36
232_P	458_G	0.544	0.36
504_I	527_Y	0.544	0.36
44_I	48_K	0.543	0.36
447_D	568_D	0.543	0.36
131_V	135_T	0.543	0.36
77_D	80_S	0.542	0.36
8_E	503_E	0.542	0.36
331_K	556_S	0.542	0.36
502_M	505_K	0.542	0.36
458_G	465_S	0.540	0.36
324_F	559_F	0.539	0.36
198_E	204_R	0.539	0.36
278_F	515_S	0.539	0.36
243_N	364_P	0.535	0.36
235_P	264_E	0.535	0.36
248_L	347_V	0.535	0.36
362_T	419_D	0.534	0.36
412_M	563_I	0.534	0.36
275_I	346_N	0.532	0.35
12_K	157_L	0.532	0.35
67_I	335_D	0.531	0.35
270_K	304_E	0.531	0.35
195_E	293_V	0.530	0.35
233_I	354_Y	0.530	0.35
453_G	523_V	0.529	0.35
38_I	45_I	0.529	0.35
199_R	203_L	0.529	0.35
250_K	412_M	0.529	0.35
178_T	202_N	0.528	0.35
14_E	92_G	0.527	0.35
365_L	423_Q	0.527	0.35
310_E	414_K	0.527	0.35
369_R	384_I	0.527	0.35
256_I	366_E	0.525	0.35
275_I	297_S	0.525	0.35
253_G	303_K	0.525	0.35
213_I	218_G	0.524	0.35
367_A	387_H	0.523	0.34
194_S	308_E	0.523	0.34
292_V	423_Q	0.523	0.34
12_K	18_S	0.523	0.34
21_Q	391_N	0.522	0.34
539_S	566_R	0.522	0.34
403_A	411_V	0.522	0.34
264_E	533_G	0.522	0.34
185_I	193_A	0.522	0.34
303_K	578_D	0.522	0.34
147_L	180_L	0.522	0.34
16_I	156_P	0.521	0.34
10_F	14_E	0.521	0.34
237_L	458_G	0.520	0.34
143_K	161_F	0.520	0.34
131_V	342_E	0.519	0.34
468_L	522_W	0.519	0.34
294_D	419_D	0.519	0.34
289_Y	327_L	0.519	0.34
308_E	431_W	0.518	0.34
256_I	373_E	0.518	0.34
468_L	520_D	0.517	0.34
529_A	565_W	0.517	0.34
327_L	453_G	0.516	0.34
391_N	582_E	0.516	0.34
252_G	391_N	0.516	0.34
74_T	168_G	0.516	0.34
195_E	424_A	0.516	0.34
201_Y	204_R	0.516	0.34
159_A	200_A	0.516	0.34
304_E	356_E	0.515	0.34
283_E	324_F	0.515	0.34
258_D	447_D	0.515	0.34
198_E	202_N	0.514	0.34
51_P	269_H	0.514	0.34
385_A	421_I	0.513	0.34
334_S	477_D	0.513	0.34
171_R	456_G	0.513	0.34
162_L	228_Q	0.510	0.33
18_S	276_F	0.510	0.33
554_G	569_K	0.510	0.33
278_F	385_A	0.510	0.33
68_K	389_Q	0.510	0.33
237_L	431_W	0.509	0.33
241_L	413_V	0.509	0.33
262_D	310_E	0.508	0.33
19_R	178_T	0.507	0.33
132_A	279_S	0.507	0.33
247_I	434_L	0.506	0.33
146_L	150_L	0.506	0.33
301_E	463_K	0.506	0.33
129_S	307_I	0.506	0.33
177_A	198_E	0.506	0.33
131_V	136_G	0.506	0.33
130_K	133_L	0.506	0.33
194_S	197_I	0.505	0.33
476_T	572_E	0.504	0.33
472_Y	528_V	0.504	0.33
174_I	466_S	0.504	0.33
460_R	493_Q	0.503	0.33
224_T	323_P	0.503	0.33
409_E	414_K	0.503	0.33
128_L	166_V	0.503	0.33
238_A	458_G	0.503	0.33
26_L	202_N	0.503	0.33
217_K	297_S	0.502	0.33
310_E	435_K	0.500	0.32
17_S	25_L	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2hivA	1	0.9584	100	0.191	Contact Map
1x9nA	1	0.9484	100	0.228	Contact Map
2cfmA	1	0.9318	100	0.232	Contact Map
3gdeA	1	0.9085	100	0.245	Contact Map
3w1bA	1	0.9002	100	0.252	Contact Map
3l2pA	1	0.8686	100	0.279	Contact Map
1vs0A	1	0.5008	100	0.578	Contact Map
1a0iA	1	0.4908	100	0.637	Contact Map
4pz7A	1	0.5358	100	0.665	Contact Map
1p16A	1	0.5591	100	0.666	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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