GREMLIN Database
Q980T3 - Uncharacterized protein
UniProt: Q980T3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 176 (136)
Sequences: 551 (374)
Seq/√Len: 32.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
40_I51_I4.5081.00
24_I135_I2.8341.00
28_D49_R2.7971.00
37_D55_D2.6921.00
107_S120_P2.6801.00
79_I141_K2.5161.00
104_Q124_K2.3970.99
42_K46_T2.2930.99
103_P135_I2.2720.99
16_G31_Y2.2510.99
11_V14_M2.2470.99
70_I89_S2.1480.99
18_I85_I2.0320.98
10_V43_I1.9010.97
110_S118_L1.8700.96
59_Y69_C1.8580.96
107_S121_K1.7810.95
77_N80_Q1.6760.93
41_L64_K1.6730.93
18_I52_I1.6690.93
17_K25_M1.6640.93
51_I64_K1.6610.93
30_L47_Q1.6300.92
137_E140_I1.5980.92
54_R75_D1.5560.91
110_S120_P1.5320.90
99_A103_P1.5090.89
52_I85_I1.5050.89
53_T80_Q1.4830.88
74_P84_F1.4770.88
55_D58_I1.4730.88
74_P80_Q1.4710.88
128_K132_W1.4700.88
72_L78_I1.4410.87
69_C73_S1.4210.86
44_A51_I1.4070.85
25_M139_I1.4060.85
17_K31_Y1.3760.84
116_M125_E1.3700.84
101_R126_Y1.3620.83
14_M31_Y1.3250.82
27_Y91_I1.2920.80
61_R71_L1.2790.79
16_G19_A1.2650.79
17_K139_I1.2350.77
37_D131_H1.2200.76
62_S89_S1.2120.76
36_E41_L1.2020.75
83_A125_E1.1980.75
15_L19_A1.1920.74
80_Q83_A1.1840.74
25_M86_A1.1790.73
9_F91_I1.1720.73
54_R84_F1.1630.72
39_K43_I1.1600.72
131_H139_I1.1480.71
18_I49_R1.1430.71
109_L131_H1.0710.66
39_K42_K1.0630.65
115_S128_K1.0620.65
29_T109_L1.0600.65
52_I81_D1.0580.65
37_D109_L1.0500.64
7_Q53_T1.0450.64
82_L120_P1.0430.64
15_L88_R1.0330.63
46_T144_S1.0240.62
87_L113_S1.0110.61
101_R106_N1.0090.61
16_G55_D1.0080.61
14_M21_W1.0050.61
109_L117_W1.0020.61
107_S118_L0.9990.61
11_V52_I0.9970.60
18_I81_D0.9880.60
14_M78_I0.9870.60
16_G37_D0.9820.59
30_L35_F0.9800.59
36_E39_K0.9760.59
11_V31_Y0.9590.57
121_K144_S0.9380.56
30_L43_I0.9230.54
120_P124_K0.9190.54
68_N90_K0.9180.54
85_I116_M0.9120.54
118_L123_K0.9080.53
28_D106_N0.9040.53
24_I103_P0.9020.53
10_V51_I0.8990.52
119_C122_C0.8830.51
6_T90_K0.8790.51
128_K136_E0.8790.51
114_E120_P0.8790.51
26_G101_R0.8750.50
89_S98_N0.8670.50
96_N143_N0.8660.50
13_S40_I0.8640.50
104_Q131_H0.8610.49
73_S84_F0.8590.49
103_P124_K0.8520.49
70_I100_T0.8470.48
14_M70_I0.8330.47
69_C98_N0.8270.47
20_R104_Q0.8240.46
107_S124_K0.8120.45
54_R74_P0.8080.45
24_I82_L0.8030.45
87_L142_A0.7980.44
108_V120_P0.7970.44
70_I73_S0.7920.44
64_K99_A0.7800.43
49_R106_N0.7720.42
134_T137_E0.7720.42
20_R134_T0.7660.42
90_K94_S0.7520.41
31_Y37_D0.7470.40
42_K140_I0.7440.40
33_N43_I0.7420.40
82_L142_A0.7380.39
37_D135_I0.7370.39
17_K109_L0.7340.39
14_M69_C0.7250.38
112_L116_M0.7170.38
59_Y78_I0.7140.38
14_M55_D0.7110.37
17_K77_N0.7100.37
19_A139_I0.6990.36
51_I58_I0.6980.36
29_T89_S0.6920.36
19_A31_Y0.6880.36
74_P141_K0.6880.36
11_V93_L0.6820.35
47_Q144_S0.6820.35
10_V123_K0.6790.35
18_I82_L0.6770.35
115_S140_I0.6770.35
8_K21_W0.6760.35
70_I130_R0.6730.34
91_I98_N0.6660.34
38_W144_S0.6650.34
117_W123_K0.6630.34
20_R78_I0.6630.34
108_V133_R0.6620.34
38_W86_A0.6580.33
22_L27_Y0.6550.33
40_I62_S0.6460.32
21_W132_W0.6450.32
42_K94_S0.6410.32
37_D40_I0.6400.32
53_T59_Y0.6390.32
111_K141_K0.6280.31
27_Y85_I0.6250.31
11_V34_D0.6220.31
43_I83_A0.6190.31
29_T143_N0.6190.31
11_V24_I0.6130.30
94_S141_K0.6120.30
81_D116_M0.6110.30
99_A130_R0.6100.30
48_K111_K0.6080.30
42_K63_L0.6010.29
59_Y73_S0.5890.29
36_E113_S0.5860.28
136_E141_K0.5860.28
10_V95_V0.5830.28
117_W132_W0.5820.28
86_A92_D0.5800.28
109_L124_K0.5770.28
57_G121_K0.5770.28
60_Y99_A0.5760.28
43_I114_E0.5760.28
32_S35_F0.5760.28
98_N124_K0.5740.28
64_K81_D0.5720.27
9_F55_D0.5700.27
20_R86_A0.5690.27
19_A114_E0.5670.27
118_L141_K0.5590.27
72_L114_E0.5580.26
27_Y130_R0.5570.26
36_E43_I0.5520.26
50_I125_E0.5490.26
96_N124_K0.5460.26
75_D110_S0.5450.26
70_I88_R0.5390.25
81_D84_F0.5390.25
14_M98_N0.5370.25
44_A63_L0.5360.25
130_R133_R0.5350.25
75_D100_T0.5350.25
89_S101_R0.5320.25
38_W111_K0.5250.24
59_Y71_L0.5240.24
18_I142_A0.5220.24
46_T94_S0.5200.24
72_L142_A0.5150.24
104_Q126_Y0.5090.23
41_L45_E0.5080.23
21_W130_R0.5060.23
114_E133_R0.5060.23
91_I116_M0.5050.23
31_Y55_D0.5020.23
86_A142_A0.5010.23
70_I84_F0.5000.23
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ga8A 1 0.2784 96.3 0.886 Contact Map
2lcqA 1 0.6477 94.4 0.9 Contact Map
3j20Y 1 0.2727 92.2 0.908 Contact Map
3o9xA 2 0.4432 84.1 0.92 Contact Map
1k82A 1 0.6818 83.9 0.921 Contact Map
2k4xA 1 0.3011 81.4 0.923 Contact Map
2d5bA 1 0.7898 77.5 0.926 Contact Map
3ziuA 1 0.7557 75.6 0.927 Contact Map
4arcA 1 0.6761 75.2 0.927 Contact Map
2v0cA 1 0.7159 73.7 0.928 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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