GREMLIN Database
PYRG - CTP synthase
UniProt: Q980S6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 535 (524)
Sequences: 2942 (1253)
Seq/√Len: 54.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
373_K377_E4.6321.00
454_L527_G4.5771.00
297_A351_V4.1041.00
295_N328_K4.0911.00
295_N330_I3.8281.00
372_I391_L3.7351.00
293_T328_K3.7241.00
405_E417_D3.6151.00
379_N503_K3.6131.00
167_G170_N3.5091.00
330_I351_V3.3021.00
296_I353_G3.2791.00
25_I262_I3.2341.00
451_A496_I3.2321.00
440_A461_Y3.0951.00
372_I505_F2.9771.00
372_I382_F2.9761.00
254_E259_V2.8131.00
172_I209_F2.7961.00
450_I453_Q2.7931.00
476_D480_D2.7731.00
248_E286_K2.7281.00
449_T484_V2.6811.00
415_T418_P2.6741.00
370_K373_K2.6651.00
354_I375_A2.6321.00
320_S327_P2.5691.00
396_F400_V2.5461.00
391_L394_V2.5411.00
403_L477_I2.5221.00
330_I350_N2.5191.00
325_V533_A2.5041.00
452_Y458_K2.3861.00
34_Y138_I2.3831.00
379_N501_S2.3831.00
484_V500_P2.3691.00
382_F392_S2.3441.00
244_E248_E2.3301.00
447_E452_Y2.3291.00
21_L211_V2.3221.00
496_I510_A2.3101.00
235_D264_S2.2981.00
124_K165_E2.2921.00
173_F205_I2.2721.00
209_F258_L2.2691.00
338_E343_N2.2681.00
183_S215_T2.2641.00
199_E202_R2.2621.00
97_F101_K2.2481.00
403_L417_D2.2051.00
81_D520_N2.1891.00
220_D224_R2.1861.00
121_D125_D2.1741.00
401_L478_L2.1721.00
323_I530_R2.1441.00
405_E416_K2.1421.00
451_A486_S2.1361.00
292_K325_V2.1101.00
408_S411_I2.0941.00
417_D474_Y2.0771.00
489_S492_G1.9691.00
450_I506_V1.9641.00
297_A332_I1.9581.00
224_R234_V1.9431.00
99_V119_V1.9161.00
162_L166_E1.9021.00
409_T418_P1.9001.00
251_I279_I1.8840.99
313_K331_W1.8770.99
447_E458_K1.8710.99
504_F528_F1.8630.99
98_E122_Q1.8590.99
365_A391_L1.8490.99
64_E440_A1.8490.99
446_K479_E1.8320.99
86_K94_K1.8290.99
64_E83_N1.7990.99
449_T486_S1.7980.99
392_S505_F1.7980.99
407_N412_N1.7970.99
478_L483_L1.7960.99
356_V382_F1.7890.99
293_T326_R1.7790.99
291_K324_G1.7690.99
56_M111_Q1.7550.99
470_V478_L1.7350.99
128_R162_L1.7330.99
30_K81_D1.7230.99
403_L474_Y1.7180.99
393_I419_V1.7130.99
454_L506_V1.7100.99
476_D479_E1.6920.99
5_Y131_S1.6660.99
122_Q125_D1.6620.99
280_S284_N1.6620.99
244_E286_K1.6380.99
284_N324_G1.6350.99
475_V488_I1.5990.98
382_F391_L1.5890.98
99_V108_Y1.5820.98
379_N502_N1.5740.98
366_E369_I1.5520.98
387_F411_I1.5350.98
504_F527_G1.5220.98
179_V218_L1.5210.98
401_L477_I1.5210.98
177_A193_L1.5200.98
383_L528_F1.5090.98
125_D129_Y1.5010.97
477_I480_D1.5000.97
15_S185_T1.5000.97
30_K82_V1.4860.97
31_R275_L1.4840.97
451_A506_V1.4830.97
446_K484_V1.4680.97
420_I470_V1.4670.97
426_Q429_V1.4660.97
442_K459_V1.4620.97
403_L416_K1.4520.97
4_K170_N1.4520.97
156_L203_I1.4460.97
138_I266_L1.4460.97
292_K533_A1.4380.97
365_A411_I1.4320.97
470_V475_V1.4240.96
393_I497_I1.4240.96
164_L231_N1.4210.96
355_I528_F1.4180.96
405_E412_N1.4160.96
353_G528_F1.4140.96
440_A515_K1.4140.96
365_A387_F1.4110.96
443_I487_G1.4100.96
175_H196_S1.4030.96
396_F481_A1.4020.96
236_H261_K1.3990.96
454_L504_F1.3960.96
22_V140_L1.3870.96
515_K522_S1.3850.96
102_K107_K1.3820.96
240_S253_L1.3740.96
443_I510_A1.3650.95
389_F470_V1.3580.95
239_S256_Q1.3540.95
337_L371_A1.3520.95
445_L451_A1.3480.95
98_E126_M1.3470.95
169_D267_K1.3460.95
238_V261_K1.3450.95
389_F497_I1.3360.95
37_T88_N1.3350.95
472_P475_V1.3310.95
38_A80_M1.3300.95
442_K461_Y1.3280.95
395_E399_D1.3250.95
407_N415_T1.3190.95
210_I226_I1.3160.94
393_I470_V1.3120.94
172_I265_R1.3090.94
25_I174_V1.3080.94
337_L347_I1.3070.94
333_E336_D1.3050.94
372_I395_E1.3000.94
64_E515_K1.2950.94
295_N351_V1.2850.94
257_K260_S1.2750.93
45_I92_A1.2700.93
8_V140_L1.2610.93
198_Q202_R1.2600.93
128_R166_E1.2580.93
298_L312_I1.2550.93
143_I159_V1.2540.93
322_Y521_P1.2490.93
444_I459_V1.2460.93
39_V141_V1.2360.92
338_E344_L1.2330.92
448_G453_Q1.2290.92
337_L343_N1.2260.92
296_I532_V1.2250.92
243_V252_I1.2240.92
285_I321_A1.2210.92
485_V488_I1.2210.92
392_S507_A1.2130.92
27_M30_K1.2120.92
45_I119_V1.2100.92
483_L497_I1.2090.92
353_G532_V1.2050.91
165_E173_F1.2020.91
127_I162_L1.1980.91
214_A239_S1.1950.91
304_K333_E1.1950.91
208_D265_R1.1910.91
401_L481_A1.1860.91
83_N517_R1.1840.91
55_Y304_K1.1820.91
109_L432_L1.1800.91
295_N350_N1.1710.90
445_L449_T1.1650.90
219_D222_T1.1630.90
92_A119_V1.1610.90
159_V173_F1.1580.90
94_K126_M1.1520.89
373_K399_D1.1510.89
421_T426_Q1.1450.89
409_T415_T1.1440.89
500_P503_K1.1440.89
444_I458_K1.1440.89
21_L176_I1.1340.89
98_E102_K1.1340.89
96_Y115_I1.1330.89
188_L219_D1.1280.88
472_P494_V1.1270.88
163_K171_V1.1250.88
488_I492_G1.1230.88
445_L487_G1.1220.88
477_I481_A1.1220.88
448_G452_Y1.1200.88
41_I141_V1.1150.88
245_T286_K1.1150.88
354_I380_I1.1110.88
81_D517_R1.1080.88
404_S417_D1.1050.87
6_I172_I1.1040.87
346_E349_G1.1010.87
355_I385_I1.0980.87
214_A241_Y1.0970.87
261_K265_R1.0960.87
172_I262_I1.0890.87
382_F505_F1.0890.87
499_L502_N1.0870.86
356_V392_S1.0820.86
41_I49_A1.0820.86
4_K266_L1.0800.86
316_I327_P1.0790.86
450_I504_F1.0780.86
245_T285_I1.0630.85
27_M31_R1.0540.85
138_I268_L1.0520.85
366_E398_R1.0500.85
20_T249_V1.0490.84
442_K490_E1.0470.84
201_R231_N1.0460.84
299_V334_S1.0450.84
396_F483_L1.0430.84
454_L528_F1.0420.84
392_S497_I1.0400.84
422_L426_Q1.0330.84
393_I478_L1.0330.84
290_S324_G1.0300.83
330_I347_I1.0300.83
220_D234_V1.0280.83
156_L205_I1.0270.83
279_I283_N1.0240.83
163_K173_F1.0230.83
260_S264_S1.0220.83
21_L240_S1.0210.83
397_A478_L1.0210.83
485_V494_V1.0150.82
41_I127_I1.0120.82
197_V207_P1.0100.82
344_L348_L1.0090.82
37_T139_T1.0050.82
251_I282_V1.0050.82
41_I75_H1.0040.82
34_Y270_D1.0010.82
445_L452_Y0.9980.81
337_L370_K0.9920.81
421_T424_D0.9900.81
9_T175_H0.9890.81
355_I368_K0.9880.81
21_L253_L0.9880.81
479_E485_V0.9880.81
412_N415_T0.9850.81
461_Y515_K0.9850.81
527_G530_R0.9830.80
248_E282_V0.9820.80
306_K331_W0.9810.80
417_D477_I0.9770.80
338_E370_K0.9700.79
163_K168_E0.9690.79
409_T421_T0.9680.79
332_I351_V0.9680.79
201_R206_Q0.9620.79
348_L351_V0.9590.79
376_R395_E0.9560.78
90_I126_M0.9560.78
355_I375_A0.9550.78
383_L506_V0.9510.78
226_I237_I0.9480.78
451_A508_T0.9450.78
174_V262_I0.9440.78
166_E170_N0.9430.78
147_V156_L0.9400.77
281_F321_A0.9390.77
393_I483_L0.9380.77
259_V273_V0.9340.77
319_A526_L0.9320.77
122_Q126_M0.9160.75
345_N378_H0.9160.75
264_S267_K0.9140.75
263_L270_D0.9080.75
217_P241_Y0.9080.75
387_F408_S0.9080.75
157_E160_R0.9070.75
312_I385_I0.9060.75
168_E208_D0.9040.74
297_A330_I0.9040.74
320_S529_I0.9010.74
101_K431_Q0.8990.74
212_G226_I0.8960.74
312_I358_P0.8950.74
82_V517_R0.8930.74
31_R273_V0.8910.73
442_K489_S0.8870.73
183_S216_L0.8850.73
38_A88_N0.8850.73
245_T282_V0.8790.72
499_L505_F0.8780.72
372_I394_V0.8770.72
193_L226_I0.8740.72
319_A323_I0.8740.72
337_L344_L0.8730.72
131_S139_T0.8730.72
339_S370_K0.8720.72
53_N56_M0.8720.72
96_Y154_P0.8710.72
254_E273_V0.8660.71
30_K80_M0.8660.71
298_L313_K0.8650.71
460_V522_S0.8630.71
109_L436_M0.8630.71
115_I119_V0.8610.71
235_D261_K0.8580.71
323_I529_I0.8580.71
105_E431_Q0.8560.70
452_Y456_G0.8550.70
49_A75_H0.8530.70
84_M88_N0.8500.70
27_M519_T0.8500.70
39_V49_A0.8410.69
214_A218_L0.8390.69
34_Y263_L0.8380.69
138_I263_L0.8380.69
32_R259_V0.8370.69
99_V156_L0.8370.69
87_Y129_Y0.8330.68
307_D312_I0.8290.68
128_R165_E0.8290.68
258_L262_I0.8270.68
35_N135_N0.8270.68
255_S279_I0.8270.68
211_V240_S0.8230.67
349_G378_H0.8220.67
496_I508_T0.8210.67
159_V171_V0.8200.67
401_L483_L0.8190.67
396_F499_L0.8180.67
417_D473_K0.8100.66
188_L222_T0.8080.66
90_I307_D0.8070.66
34_Y137_E0.8060.66
315_A319_A0.8060.66
217_P239_S0.8040.66
474_Y477_I0.8030.65
344_L370_K0.8030.65
319_A529_I0.8030.65
45_I99_V0.8030.65
181_Y185_T0.8000.65
209_F261_K0.7950.65
180_E193_L0.7940.65
16_V21_L0.7930.64
310_I317_Y0.7930.64
252_I255_S0.7920.64
297_A352_N0.7910.64
485_V497_I0.7910.64
294_I532_V0.7900.64
389_F508_T0.7870.64
464_H495_E0.7850.64
374_Y378_H0.7830.63
163_K231_N0.7810.63
404_S416_K0.7800.63
462_E522_S0.7800.63
131_S136_A0.7790.63
243_V249_V0.7790.63
41_I90_I0.7780.63
319_A327_P0.7770.63
450_I454_L0.7730.62
379_N500_P0.7720.62
423_L426_Q0.7720.62
349_G374_Y0.7700.62
354_I528_F0.7670.62
295_N352_N0.7650.62
369_I391_L0.7630.61
67_A86_K0.7590.61
223_R256_Q0.7590.61
95_V126_M0.7590.61
177_A180_E0.7570.61
444_I492_G0.7560.61
394_V407_N0.7540.61
339_S343_N0.7510.60
210_I232_V0.7480.60
61_F83_N0.7470.60
292_K324_G0.7460.60
39_V88_N0.7420.59
527_G531_A0.7400.59
444_I490_E0.7400.59
64_E461_Y0.7380.59
451_A507_A0.7370.59
39_V140_L0.7370.59
63_T67_A0.7370.59
421_T427_K0.7370.59
353_G383_L0.7340.58
223_R239_S0.7340.58
89_N109_L0.7330.58
450_I501_S0.7330.58
61_F517_R0.7320.58
116_I120_T0.7310.58
442_K491_N0.7290.58
98_E101_K0.7290.58
16_V176_I0.7280.58
425_E436_M0.7270.58
260_S270_D0.7260.58
130_A139_T0.7250.58
240_S256_Q0.7230.57
343_N346_E0.7220.57
355_I392_S0.7210.57
299_V356_V0.7200.57
120_T161_Q0.7180.57
372_I392_S0.7160.57
475_V494_V0.7160.57
202_R489_S0.7150.56
332_I337_L0.7140.56
124_K161_Q0.7130.56
497_I505_F0.7130.56
236_H265_R0.7110.56
169_D265_R0.7090.56
63_T69_T0.7080.56
277_D519_T0.7080.56
426_Q430_T0.7050.55
166_E171_V0.7040.55
188_L216_L0.7040.55
521_P526_L0.7020.55
34_Y269_E0.6970.55
277_D280_S0.6970.55
115_I150_I0.6960.54
446_K449_T0.6960.54
443_I451_A0.6960.54
185_T242_D0.6950.54
282_V286_K0.6930.54
198_Q201_R0.6920.54
83_N440_A0.6900.54
32_R263_L0.6890.54
375_A382_F0.6880.54
368_K391_L0.6870.53
401_L479_E0.6860.53
526_L530_R0.6850.53
114_Q151_E0.6840.53
254_E272_Q0.6830.53
52_M60_V0.6820.53
448_G484_V0.6820.53
371_A375_A0.6820.53
281_F285_I0.6810.53
446_K488_I0.6810.53
163_K208_D0.6790.53
55_Y61_F0.6780.53
488_I494_V0.6780.53
306_K313_K0.6780.53
312_I357_L0.6780.53
365_A394_V0.6780.53
233_K265_R0.6770.52
184_V227_A0.6770.52
9_T196_S0.6760.52
487_G496_I0.6760.52
335_T363_R0.6760.52
290_S326_R0.6760.52
209_F256_Q0.6750.52
366_E407_N0.6720.52
350_N380_I0.6710.52
16_V178_L0.6710.52
343_N370_K0.6700.52
64_E514_F0.6700.52
281_F519_T0.6690.52
179_V239_S0.6690.52
497_I507_A0.6690.52
344_L347_I0.6690.52
94_K98_E0.6680.51
385_I508_T0.6670.51
39_V90_I0.6640.51
336_D347_I0.6620.51
49_A181_Y0.6600.51
182_L185_T0.6590.50
218_L222_T0.6580.50
337_L345_N0.6570.50
15_S240_S0.6560.50
67_A94_K0.6560.50
37_T136_A0.6550.50
396_F478_L0.6540.50
373_K378_H0.6490.49
378_H447_E0.6490.49
263_L268_L0.6480.49
517_R520_N0.6470.49
365_A408_S0.6470.49
319_A322_Y0.6460.49
209_F236_H0.6460.49
403_L415_T0.6460.49
154_P195_H0.6450.49
212_G436_M0.6450.49
339_S344_L0.6450.49
387_F391_L0.6440.49
506_V524_I0.6430.49
305_L308_S0.6420.49
85_T88_N0.6410.49
101_K105_E0.6380.48
383_L527_G0.6370.48
362_S411_I0.6360.48
5_Y128_R0.6360.48
45_I331_W0.6350.48
102_K122_Q0.6350.48
340_D345_N0.6330.48
81_D519_T0.6320.48
399_D404_S0.6300.47
95_V122_Q0.6300.47
47_V52_M0.6300.47
61_F80_M0.6290.47
121_D224_R0.6290.47
143_I156_L0.6290.47
369_I372_I0.6290.47
105_E432_L0.6280.47
443_I496_I0.6280.47
259_V263_L0.6270.47
475_V485_V0.6270.47
26_G140_L0.6260.47
365_A407_N0.6260.47
7_V159_V0.6260.47
25_I258_L0.6260.47
470_V494_V0.6240.47
316_I355_I0.6240.47
8_V38_A0.6240.47
369_I399_D0.6240.47
424_D427_K0.6220.47
345_N349_G0.6220.47
248_E251_I0.6210.46
343_N347_I0.6200.46
171_V205_I0.6190.46
37_T80_M0.6180.46
445_L496_I0.6170.46
425_E432_L0.6150.46
433_G438_L0.6140.46
400_V478_L0.6140.46
241_Y252_I0.6120.45
227_A233_K0.6090.45
403_L407_N0.6090.45
100_I249_V0.6090.45
284_N322_Y0.6090.45
115_I154_P0.6080.45
248_E283_N0.6080.45
195_H198_Q0.6070.45
34_Y268_L0.6070.45
470_V496_I0.6070.45
276_T279_I0.6070.45
322_Y526_L0.6060.45
396_F401_L0.6060.45
299_V371_A0.6050.45
25_I211_V0.6050.45
231_N236_H0.6030.45
486_S499_L0.6030.45
260_S272_Q0.6010.44
34_Y253_L0.6000.44
323_I533_A0.6000.44
355_I508_T0.5990.44
249_V256_Q0.5980.44
316_I329_L0.5960.44
510_A522_S0.5920.43
389_F510_A0.5910.43
15_S190_T0.5910.43
45_I115_I0.5910.43
130_A136_A0.5900.43
375_A392_S0.5900.43
184_V242_D0.5890.43
182_L239_S0.5890.43
126_M424_D0.5890.43
454_L526_L0.5880.43
385_I525_Y0.5880.43
411_I415_T0.5880.43
433_G469_E0.5870.43
393_I396_F0.5870.43
355_I529_I0.5870.43
423_L436_M0.5870.43
36_V476_D0.5860.43
138_I270_D0.5860.43
107_K111_Q0.5850.43
441_Q489_S0.5850.43
320_S325_V0.5830.42
116_I352_N0.5820.42
195_H199_E0.5820.42
522_S525_Y0.5810.42
481_A499_L0.5810.42
209_F262_I0.5800.42
87_Y94_K0.5800.42
3_N139_T0.5780.42
97_F100_I0.5770.42
124_K231_N0.5770.42
449_T487_G0.5770.42
486_S496_I0.5770.42
71_L112_T0.5750.42
504_F524_I0.5740.41
383_L508_T0.5740.41
305_L383_L0.5740.41
37_T53_N0.5740.41
73_L94_K0.5740.41
306_K312_I0.5730.41
401_L405_E0.5730.41
389_F496_I0.5730.41
369_I373_K0.5710.41
116_I423_L0.5700.41
15_S163_K0.5690.41
39_V75_H0.5680.41
30_K83_N0.5680.41
488_I491_N0.5680.41
233_K236_H0.5680.41
41_I126_M0.5670.41
296_I529_I0.5670.41
221_E224_R0.5660.41
432_L436_M0.5660.41
263_L269_E0.5660.41
514_F518_P0.5650.41
163_K206_Q0.5640.40
343_N348_L0.5630.40
186_G305_L0.5630.40
244_E399_D0.5620.40
395_E505_F0.5610.40
111_Q489_S0.5600.40
29_L262_I0.5600.40
373_K395_E0.5590.40
67_A188_L0.5590.40
34_Y271_R0.5590.40
8_V24_S0.5580.40
506_V527_G0.5560.40
102_K125_D0.5560.40
446_K486_S0.5560.40
150_I237_I0.5550.39
186_G242_D0.5550.39
179_V212_G0.5540.39
230_T487_G0.5540.39
120_T229_F0.5540.39
39_V130_A0.5530.39
308_S391_L0.5520.39
21_L329_L0.5510.39
407_N411_I0.5510.39
318_H516_S0.5510.39
368_K460_V0.5510.39
88_N130_A0.5510.39
166_E173_F0.5500.39
41_I94_K0.5500.39
16_V166_E0.5500.39
15_S259_V0.5490.39
276_T280_S0.5470.39
313_K317_Y0.5470.39
508_T514_F0.5460.39
63_T75_H0.5440.38
451_A524_I0.5440.38
315_A508_T0.5430.38
312_I426_Q0.5430.38
469_E493_L0.5420.38
52_M56_M0.5410.38
317_Y321_A0.5400.38
332_I348_L0.5400.38
281_F358_P0.5390.38
51_T434_G0.5390.38
129_Y267_K0.5380.38
484_V499_L0.5360.38
196_S200_L0.5360.38
49_A141_V0.5360.38
349_G373_K0.5360.38
464_H469_E0.5350.37
275_L279_I0.5350.37
441_Q490_E0.5350.37
499_L503_K0.5350.37
147_V243_V0.5340.37
90_I147_V0.5330.37
89_N92_A0.5330.37
16_V185_T0.5330.37
35_N134_N0.5330.37
85_T473_K0.5320.37
391_L411_I0.5310.37
120_T124_K0.5310.37
243_V248_E0.5310.37
377_E395_E0.5300.37
355_I371_A0.5300.37
280_S283_N0.5300.37
425_E506_V0.5290.37
312_I321_A0.5290.37
102_K126_M0.5290.37
168_E233_K0.5290.37
188_L214_A0.5290.37
323_I526_L0.5280.37
383_L507_A0.5280.37
296_I385_I0.5280.37
127_I159_V0.5280.37
129_Y424_D0.5280.37
443_I493_L0.5280.37
30_K517_R0.5270.37
254_E257_K0.5270.37
90_I95_V0.5250.36
443_I486_S0.5250.36
208_D264_S0.5240.36
174_V332_I0.5220.36
30_K310_I0.5210.36
20_T298_L0.5210.36
160_R178_L0.5210.36
371_A395_E0.5200.36
245_T321_A0.5200.36
98_E125_D0.5200.36
176_I231_N0.5200.36
127_I139_T0.5200.36
423_L515_K0.5200.36
38_A82_V0.5180.36
280_S404_S0.5180.36
171_V305_L0.5180.36
327_P533_A0.5170.36
441_Q493_L0.5170.36
130_A135_N0.5160.36
443_I460_V0.5160.36
251_I273_V0.5160.36
88_N310_I0.5160.36
333_E391_L0.5150.35
121_D161_Q0.5150.35
27_M277_D0.5150.35
444_I491_N0.5150.35
167_G394_V0.5150.35
56_M357_L0.5150.35
21_L27_M0.5150.35
312_I525_Y0.5150.35
53_N510_A0.5140.35
453_Q527_G0.5140.35
354_I374_Y0.5140.35
121_D214_A0.5130.35
212_G382_F0.5130.35
75_H181_Y0.5120.35
73_L112_T0.5120.35
297_A375_A0.5120.35
450_I500_P0.5120.35
214_A457_K0.5120.35
260_S263_L0.5110.35
230_T299_V0.5100.35
435_T438_L0.5100.35
116_I177_A0.5090.35
358_P411_I0.5090.35
254_E279_I0.5090.35
370_K374_Y0.5090.35
447_E457_K0.5090.35
149_D161_Q0.5090.35
386_C433_G0.5090.35
517_R521_P0.5090.35
226_I239_S0.5080.35
179_V242_D0.5070.35
21_L310_I0.5070.35
206_Q231_N0.5060.35
83_N176_I0.5060.35
13_L182_L0.5060.35
75_H497_I0.5060.35
357_L518_P0.5060.35
116_I199_E0.5050.34
497_I508_T0.5050.34
451_A510_A0.5050.34
200_L205_I0.5040.34
67_A178_L0.5030.34
238_V257_K0.5030.34
126_M163_K0.5030.34
43_P112_T0.5030.34
111_Q282_V0.5020.34
164_L508_T0.5020.34
499_L506_V0.5020.34
26_G391_L0.5020.34
56_M60_V0.5020.34
405_E477_I0.5020.34
198_Q206_Q0.5010.34
203_I227_A0.5010.34
334_S507_A0.5010.34
3_N331_W0.5010.34
323_I504_F0.5010.34
6_I449_T0.5000.34
355_I383_L0.5000.34
38_A85_T0.5000.34
61_F179_V0.5000.34
233_K391_L0.5000.34
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4zdjA 4 0.9757 100 0.395 Contact Map
3nvaA 2 0.9963 100 0.412 Contact Map
1vcoA 4 0.9776 100 0.448 Contact Map
2vo1A 4 0.428 100 0.468 Contact Map
1s1mA 4 0.9701 100 0.51 Contact Map
2v4uA 1 0.4542 100 0.789 Contact Map
2w7tA 1 0.4486 100 0.814 Contact Map
1l9xA 1 0.4131 100 0.898 Contact Map
4l8fC 3 0.4075 100 0.898 Contact Map
3uowA 2 0.3907 99.9 0.899 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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