GREMLIN Database
RL30E - 50S ribosomal protein L30e
UniProt: Q980R3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 108 (99)
Sequences: 410 (214)
Seq/√Len: 21.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
40_V92_S5.0981.00
59_H63_L2.4850.98
11_F71_Y2.4040.97
26_F88_I2.0420.93
53_L56_D2.0320.93
48_T75_G1.9820.92
45_V57_I1.9780.92
28_A53_L1.9640.92
54_K58_M1.8610.89
31_A92_S1.8170.88
61_A68_V1.7650.87
80_T98_D1.7410.86
18_L91_I1.7180.85
47_S72_K1.6840.84
56_D66_I1.6700.83
50_R75_G1.6260.82
19_L24_V1.5610.79
99_S102_L1.5560.79
42_M81_L1.5530.78
31_A38_S1.5270.77
67_P102_L1.4710.75
24_V84_K1.4540.74
15_L20_K1.4540.74
39_K68_V1.4400.73
14_E100_K1.4330.73
78_L88_I1.4250.72
47_S67_P1.4160.72
15_L19_L1.3710.69
21_T26_F1.3340.67
27_G79_G1.3260.66
18_L82_C1.3190.66
48_T59_H1.2900.64
13_G17_S1.2870.64
11_F32_I1.2460.61
7_Q10_S1.2240.60
46_A91_I1.1700.57
65_N94_I1.1540.55
31_A90_T1.1530.55
37_L46_A1.1520.55
60_Y63_L1.1500.55
31_A43_V1.1310.54
10_S102_L1.1200.53
39_K43_V1.1110.53
6_E65_N1.0900.51
93_I101_I1.0860.51
34_Y59_H1.0790.50
67_P103_D1.0730.50
85_P103_D1.0690.50
21_T60_Y1.0620.49
39_K55_Q1.0610.49
25_I93_I1.0460.48
91_I94_I1.0330.47
45_V65_N1.0290.47
13_G24_V1.0250.47
75_G87_M1.0240.47
43_V77_D1.0040.45
32_I41_K0.9890.44
45_V85_P0.9870.44
19_L31_A0.9750.43
77_D89_S0.9700.43
71_Y100_K0.9620.43
39_K54_K0.9480.42
62_K69_Y0.9470.42
16_K42_M0.9280.40
12_E71_Y0.9270.40
66_I72_K0.8960.38
19_L91_I0.8920.38
87_M95_D0.8900.38
34_Y92_S0.8860.38
87_M100_K0.8820.37
29_K32_I0.8780.37
26_F33_K0.8710.37
50_R98_D0.8450.35
47_S69_Y0.8360.35
34_Y86_F0.8310.34
18_L80_T0.8260.34
43_V64_S0.8190.34
18_L48_T0.8110.33
74_S82_C0.8080.33
65_N100_K0.8050.33
41_K74_S0.7940.32
70_E95_D0.7940.32
8_Q34_Y0.7930.32
59_H75_G0.7930.32
10_S20_K0.7840.31
56_D64_S0.7800.31
38_S48_T0.7670.31
74_S77_D0.7420.29
30_R38_S0.7420.29
39_K80_T0.7370.29
83_G93_I0.7370.29
14_E75_G0.7310.28
11_F26_F0.7300.28
15_L56_D0.7220.28
16_K45_V0.7210.28
17_S59_H0.7180.28
54_K93_I0.7120.27
37_L44_I0.7110.27
65_N71_Y0.7000.27
76_W87_M0.6990.27
23_K58_M0.6860.26
79_G101_I0.6850.26
13_G45_V0.6780.26
64_S80_T0.6760.26
98_D101_I0.6670.25
26_F98_D0.6610.25
8_Q46_A0.6540.24
22_G57_I0.6460.24
40_V96_E0.6460.24
25_I30_R0.6370.24
44_I78_L0.6360.24
84_K88_I0.6340.23
42_M92_S0.6310.23
46_A81_L0.6290.23
29_K95_D0.6210.23
47_S77_D0.6190.23
65_N99_S0.6110.22
79_G84_K0.6110.22
54_K70_E0.6100.22
17_S58_M0.6080.22
44_I93_I0.6020.22
39_K77_D0.6020.22
29_K33_K0.6000.22
30_R52_D0.5980.22
25_I44_I0.5870.21
38_S66_I0.5850.21
24_V102_L0.5810.21
6_E9_V0.5780.21
38_S42_M0.5780.21
28_A89_S0.5720.21
74_S86_F0.5720.21
25_I76_W0.5640.20
67_P94_I0.5580.20
34_Y61_A0.5560.20
37_L89_S0.5520.20
28_A32_I0.5500.20
16_K103_D0.5430.19
15_L100_K0.5390.19
37_L77_D0.5360.19
25_I51_G0.5270.19
68_V100_K0.5180.18
29_K49_L0.5170.18
15_L98_D0.5160.18
22_G27_G0.5150.18
88_I91_I0.5090.18
69_Y75_G0.5050.18
40_V82_C0.5030.18
26_F55_Q0.5000.18
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1w41A 1 0.9167 99.9 0.458 Contact Map
3cpqA 2 0.9259 99.9 0.46 Contact Map
1vx76 1 0.9074 99.9 0.465 Contact Map
3j61c 1 1 99.9 0.468 Contact Map
3j21Z 1 0.9167 99.9 0.468 Contact Map
3zf7g 1 0.8889 99.9 0.476 Contact Map
3u5ec 1 0.8981 99.9 0.484 Contact Map
3vi6A 3 0.8981 99.9 0.486 Contact Map
4a18G 1 0.8889 99.9 0.487 Contact Map
4nutA 1 0.9722 99.8 0.541 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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