GREMLIN Database
RPOA1 - DNA-directed RNA polymerase subunit A'
UniProt: Q980R2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 880 (796)
Sequences: 2742 (1259)
Seq/√Len: 44.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
20_R76_E8.0201.00
664_E707_L6.3671.00
23_S74_H5.5591.00
706_K710_T5.5321.00
336_E414_G5.4171.00
336_E436_R5.2491.00
339_V464_L5.1031.00
675_L703_T4.7761.00
516_L520_E4.4811.00
538_A547_T4.4661.00
667_R671_E4.4221.00
155_K210_T4.3601.00
146_C157_K3.7881.00
418_L430_M3.6151.00
433_H453_Y3.5561.00
418_L476_A3.4071.00
470_E473_I3.4071.00
519_E543_R3.3881.00
667_R710_T3.3581.00
656_D714_I3.3011.00
668_A703_T3.3001.00
104_V111_I3.2481.00
75_I214_V3.2271.00
582_H585_Y3.1461.00
123_K161_P3.1161.00
432_A476_A3.0401.00
16_P206_W2.9951.00
413_D436_R2.9751.00
360_K412_I2.9751.00
163_N166_E2.9541.00
82_I208_I2.9521.00
671_E674_N2.9481.00
98_C101_C2.9011.00
708_R741_T2.8901.00
581_P585_Y2.8491.00
581_P584_S2.8281.00
516_L519_E2.7801.00
333_S629_D2.7161.00
27_I49_L2.7161.00
662_Y666_D2.6881.00
516_L521_A2.6671.00
623_Y626_W2.6431.00
360_K363_Q2.6381.00
78_V246_N2.5951.00
96_A111_I2.5921.00
517_T540_L2.5731.00
239_L276_Y2.5671.00
358_I362_R2.5591.00
713_D717_K2.5461.00
141_M144_Q2.5241.00
517_T520_E2.5221.00
716_S737_V2.5051.00
669_K783_Y2.5051.00
645_T724_F2.4441.00
701_L751_S2.4251.00
373_P410_H2.4151.00
545_Y548_G2.3891.00
663_N667_R2.3811.00
97_T183_R2.3791.00
322_S343_I2.3271.00
378_V397_L2.3231.00
702_D706_K2.3101.00
411_L466_V2.3061.00
473_I477_K2.2851.00
209_L212_L2.2671.00
360_K373_P2.2661.00
20_R211_V2.2601.00
521_A543_R2.2411.00
678_K699_Y2.2261.00
677_Q681_N2.1421.00
589_K592_I2.1301.00
750_Q786_F2.1301.00
586_V593_L2.1261.00
592_I597_V2.1091.00
25_T49_L2.1071.00
705_D709_S2.0971.00
417_V435_V2.0700.99
146_C149_C2.0620.99
752_V776_P2.0560.99
725_A743_M2.0410.99
615_L627_L2.0380.99
343_I443_F2.0340.99
670_V673_D2.0260.99
175_L187_I2.0110.99
68_C71_H2.0100.99
488_T491_Y1.9960.99
359_E363_Q1.9910.99
121_I127_S1.9900.99
238_K241_D1.9800.99
546_Y550_Q1.9800.99
93_F194_I1.9800.99
61_C71_H1.9740.99
496_I628_M1.9580.99
593_L596_G1.9580.99
671_E703_T1.9290.99
517_T543_R1.9260.99
342_I441_L1.9230.99
623_Y630_N1.9140.99
593_L598_F1.9140.99
168_R194_I1.9120.99
582_H588_I1.9050.99
81_V273_V1.8990.99
253_I262_I1.8960.99
589_K594_L1.8840.99
867_D871_I1.8820.99
668_A707_L1.8800.99
90_I184_L1.8760.99
58_C61_C1.8750.99
127_S132_L1.8280.99
540_L543_R1.8060.98
845_V848_V1.8030.98
180_I184_L1.8010.98
280_E283_G1.7910.98
438_L444_R1.7900.98
580_C585_Y1.7820.98
589_K593_L1.7760.98
71_H101_C1.7460.98
334_I482_V1.7380.98
671_E706_K1.7290.98
581_P588_I1.7290.98
710_T713_D1.7210.98
598_F603_I1.7160.98
82_I105_K1.7120.98
592_I598_F1.7100.98
181_R185_E1.6970.98
114_Y118_Y1.6920.98
520_E544_E1.6890.98
524_I539_I1.6830.98
825_N828_S1.6830.98
548_G551_V1.6810.98
867_D870_R1.6810.98
434_R477_K1.6640.97
585_Y588_I1.6630.97
666_D670_V1.6620.97
537_P542_P1.6610.97
589_K598_F1.6600.97
587_V595_E1.6530.97
476_A480_M1.6500.97
167_E170_E1.6490.97
215_P239_L1.6450.97
418_L432_A1.6420.97
552_I598_F1.6320.97
474_A478_E1.6290.97
521_A524_I1.6260.97
478_E484_K1.6140.97
646_M725_A1.6060.97
331_N444_R1.6050.97
91_Y95_K1.5960.97
334_I496_I1.5940.97
620_S624_G1.5900.97
430_M476_A1.5900.97
713_D737_V1.5840.96
18_E21_K1.5830.96
150_N153_Q1.5780.96
166_E170_E1.5700.96
753_R800_A1.5670.96
71_H98_C1.5600.96
341_E439_K1.5470.96
449_V482_V1.5430.96
663_N666_D1.5340.96
336_E434_R1.5270.96
34_D40_I1.5210.96
548_G552_I1.5000.95
664_E710_T1.4970.95
129_A132_L1.4970.95
443_F464_L1.4920.95
76_E211_V1.4840.95
579_D584_S1.4780.95
581_P587_V1.4760.95
113_K147_P1.4690.95
672_V700_I1.4650.95
14_L22_M1.4610.94
753_R777_E1.4610.94
783_Y794_E1.4600.94
537_P550_Q1.4560.94
379_I408_E1.4510.94
674_N678_K1.4390.94
518_K543_R1.4360.94
545_Y550_Q1.4320.94
121_I125_W1.4290.94
620_S623_Y1.4220.94
429_S452_P1.4200.94
28_I42_G1.4190.94
165_Y198_D1.4150.93
358_I386_I1.4150.93
509_L516_L1.4140.93
449_V636_I1.4100.93
667_R670_V1.4100.93
559_D590_N1.4030.93
651_V725_A1.3990.93
148_H157_K1.3920.93
729_A740_I1.3900.93
173_A177_P1.3850.93
577_N582_H1.3810.93
168_R198_D1.3770.92
451_P499_A1.3760.92
583_D588_I1.3720.92
556_L560_F1.3720.92
747_L750_Q1.3710.92
238_K272_H1.3690.92
840_S844_E1.3650.92
603_I645_T1.3650.92
124_R127_S1.3550.92
581_P589_K1.3490.92
834_Y837_T1.3480.92
29_T42_G1.3400.91
416_I477_K1.3360.91
479_I485_N1.3360.91
160_K203_R1.3320.91
181_R210_T1.3280.91
488_T495_I1.3270.91
167_E194_I1.3200.91
524_I533_D1.3190.91
189_D199_P1.3160.91
322_S464_L1.3150.91
585_Y591_G1.3120.91
521_A554_A1.3080.90
539_I583_D1.3060.90
297_T300_Q1.3050.90
112_E127_S1.3050.90
584_S591_G1.3050.90
670_V674_N1.3040.90
155_K160_K1.2970.90
121_I124_R1.2970.90
516_L524_I1.2910.90
580_C583_D1.2890.90
136_V141_M1.2890.90
246_N249_L1.2830.90
585_Y589_K1.2800.89
509_L638_F1.2780.89
726_Y730_R1.2670.89
802_G805_G1.2600.89
784_S794_E1.2590.89
582_H589_K1.2480.88
665_I669_K1.2440.88
530_V534_L1.2360.88
451_P605_N1.2310.87
596_G600_K1.2290.87
849_A852_D1.2280.87
546_Y549_K1.2250.87
669_K673_D1.2240.87
113_K121_I1.2240.87
584_S589_K1.2240.87
486_I616_I1.2190.87
548_G556_L1.2060.86
102_G186_K1.2040.86
588_I593_L1.2030.86
525_L554_A1.2020.86
750_Q798_H1.1960.86
347_L411_L1.1960.86
578_E585_Y1.1940.86
235_L298_L1.1920.86
711_A745_A1.1870.85
752_V812_R1.1850.85
357_N409_R1.1840.85
13_I86_L1.1810.85
778_A782_I1.1810.85
835_D839_R1.1810.85
274_A281_I1.1800.85
580_C588_I1.1790.85
678_K683_E1.1740.85
104_V208_I1.1680.85
583_D589_K1.1660.84
518_K540_L1.1640.84
195_L198_D1.1640.84
808_D813_T1.1630.84
318_V465_H1.1630.84
712_G741_T1.1620.84
82_I180_I1.1620.84
272_H275_T1.1580.84
747_L798_H1.1580.84
258_P293_R1.1580.84
125_W128_A1.1540.84
373_P407_I1.1520.84
175_L180_I1.1430.83
830_L846_V1.1420.83
588_I591_G1.1410.83
535_G553_S1.1400.83
615_L619_Y1.1400.83
424_S429_S1.1340.83
83_H86_L1.1240.82
699_Y702_D1.1220.82
708_R738_L1.1220.82
813_T818_Y1.1220.82
39_P43_S1.1210.82
493_G609_E1.1200.82
103_R148_H1.1180.82
583_D591_G1.1170.82
582_H587_V1.1150.82
481_L484_K1.1130.82
418_L453_Y1.1120.81
20_R210_T1.1100.81
214_V273_V1.1090.81
637_R641_L1.1090.81
96_A104_V1.1070.81
536_E540_L1.1040.81
255_A261_I1.1030.81
15_S206_W1.1010.81
581_P586_V1.0990.81
122_K125_W1.0990.81
853_D856_F1.0950.80
161_P164_F1.0950.80
547_T550_Q1.0920.80
847_Q850_Y1.0900.80
557_P591_G1.0870.80
697_E779_R1.0840.80
87_V496_I1.0820.80
25_T48_R1.0810.80
612_L628_M1.0810.80
521_A551_V1.0730.79
374_G410_H1.0730.79
490_R786_F1.0720.79
551_V556_L1.0710.79
549_K552_I1.0700.79
347_L466_V1.0680.79
15_S18_E1.0660.79
165_Y169_K1.0660.79
68_C357_N1.0650.79
751_S801_G1.0630.78
805_G808_D1.0620.78
793_T807_V1.0610.78
41_E59_P1.0580.78
664_E667_R1.0580.78
335_D434_R1.0570.78
331_N633_R1.0550.78
539_I543_R1.0540.78
135_Y138_K1.0540.78
552_I593_L1.0540.78
77_L83_H1.0530.78
432_A481_L1.0520.78
808_D812_R1.0500.78
539_I545_Y1.0490.78
251_E255_A1.0490.78
29_T40_I1.0480.77
578_E582_H1.0470.77
792_P800_A1.0470.77
17_D20_R1.0460.77
353_I466_V1.0450.77
193_E645_T1.0450.77
203_R206_W1.0370.77
732_G735_G1.0310.76
656_D718_Y1.0310.76
342_I393_D1.0290.76
686_P696_L1.0270.76
861_A865_T1.0260.76
120_A124_R1.0250.76
614_W618_E1.0240.76
79_R178_S1.0230.76
537_P541_A1.0200.76
801_G805_G1.0160.75
549_K553_S1.0160.75
627_L631_L1.0130.75
548_G553_S1.0120.75
118_Y121_I1.0110.75
661_I788_T1.0050.74
149_C158_L1.0040.74
61_C101_C1.0000.74
335_D483_H1.0000.74
90_I98_C0.9960.74
716_S736_S0.9950.74
113_K117_I0.9900.73
268_L272_H0.9890.73
599_D603_I0.9890.73
581_P598_F0.9850.73
101_C149_C0.9850.73
360_K410_H0.9840.73
361_L407_I0.9810.73
466_V625_K0.9800.73
324_T814_S0.9790.72
588_I592_I0.9790.72
237_H295_L0.9770.72
86_L299_A0.9750.72
181_R184_L0.9720.72
865_T870_R0.9710.72
173_A179_D0.9700.72
508_L642_Q0.9700.72
581_P591_G0.9680.72
548_G583_D0.9680.72
381_P405_Y0.9640.71
279_N296_R0.9630.71
549_K583_D0.9630.71
412_I427_R0.9620.71
26_A76_E0.9600.71
233_D236_T0.9520.70
593_L597_V0.9470.70
241_D272_H0.9460.70
542_P550_Q0.9450.70
180_I208_I0.9440.70
136_V144_Q0.9430.70
502_Y632_F0.9420.70
552_I557_P0.9420.70
50_G61_C0.9400.69
615_L784_S0.9380.69
675_L696_L0.9370.69
125_W131_R0.9370.69
676_I680_K0.9360.69
415_D473_I0.9360.69
426_H456_D0.9350.69
579_D585_Y0.9340.69
516_L543_R0.9340.69
341_E345_K0.9330.69
124_R128_A0.9320.69
32_V44_V0.9310.69
217_I505_G0.9280.68
23_S28_I0.9280.68
656_D710_T0.9280.68
334_I628_M0.9240.68
808_D818_Y0.9240.68
450_C739_N0.9240.68
548_G591_G0.9230.68
509_L551_V0.9220.68
150_N159_E0.9210.68
13_I207_M0.9200.68
583_D598_F0.9190.68
304_G308_R0.9190.68
506_A603_I0.9170.67
485_N645_T0.9160.67
674_N681_N0.9150.67
800_A807_V0.9150.67
334_I585_Y0.9120.67
557_P560_F0.9120.67
213_P837_T0.9120.67
414_G434_R0.9110.67
651_V786_F0.9090.67
225_I231_A0.9090.67
443_F453_Y0.9030.66
150_N154_Y0.9010.66
583_D587_V0.9010.66
15_S19_I0.9000.66
519_E524_I0.9000.66
752_V785_S0.8980.66
248_R265_L0.8960.66
626_W630_N0.8930.65
75_I83_H0.8900.65
716_S786_F0.8900.65
212_L517_T0.8880.65
380_R405_Y0.8870.65
196_G212_L0.8850.65
212_L277_F0.8850.65
509_L634_V0.8840.65
103_R109_D0.8830.64
709_S737_V0.8830.64
126_P186_K0.8810.64
848_V856_F0.8800.64
584_S588_I0.8800.64
129_A134_E0.8790.64
522_Q538_A0.8780.64
75_I80_P0.8760.64
72_F213_P0.8750.64
9_I12_G0.8740.64
592_I596_G0.8740.64
616_I624_G0.8720.63
588_I597_V0.8720.63
375_A410_H0.8710.63
535_G554_A0.8710.63
35_E40_I0.8710.63
697_E776_P0.8710.63
113_K126_P0.8670.63
381_P385_R0.8650.63
738_L741_T0.8640.63
17_D121_I0.8620.63
240_V245_I0.8620.63
48_R647_R0.8620.63
70_G101_C0.8620.63
587_V591_G0.8620.63
559_D564_G0.8610.62
834_Y839_R0.8600.62
513_T516_L0.8600.62
6_I19_I0.8590.62
231_A258_P0.8580.62
708_R712_G0.8580.62
552_I556_L0.8570.62
603_I611_I0.8550.62
227_S362_R0.8550.62
61_C68_C0.8540.62
778_A797_F0.8540.62
114_Y117_I0.8530.62
698_N752_V0.8530.62
586_V598_F0.8510.62
118_Y144_Q0.8510.62
580_C589_K0.8500.61
611_I783_Y0.8480.61
655_D663_N0.8480.61
508_L727_V0.8470.61
492_G819_M0.8460.61
153_Q159_E0.8450.61
548_G557_P0.8440.61
811_V820_Q0.8440.61
777_E791_K0.8430.61
255_A260_L0.8420.61
242_I830_L0.8410.61
557_P564_G0.8400.61
113_K148_H0.8400.61
117_I122_K0.8390.60
537_P545_Y0.8390.60
357_N847_Q0.8370.60
604_G712_G0.8350.60
850_Y853_D0.8340.60
162_Y167_E0.8310.60
596_G599_D0.8310.60
257_A261_I0.8310.60
818_Y821_R0.8300.60
18_E67_N0.8290.60
809_T813_T0.8290.60
104_V191_D0.8290.60
304_G313_L0.8270.59
849_A854_G0.8260.59
80_P83_H0.8250.59
438_L743_M0.8250.59
535_G546_Y0.8240.59
517_T542_P0.8220.59
447_L819_M0.8220.59
222_S378_V0.8210.59
334_I486_I0.8200.59
806_L811_V0.8200.59
486_I494_P0.8200.59
61_C98_C0.8190.59
120_A125_W0.8180.58
585_Y595_E0.8180.58
126_P132_L0.8180.58
550_Q553_S0.8180.58
331_N436_R0.8170.58
530_V583_D0.8170.58
118_Y128_A0.8160.58
425_L454_N0.8160.58
262_I303_K0.8150.58
583_D586_V0.8150.58
595_E598_F0.8140.58
136_V146_C0.8140.58
70_G73_G0.8130.58
383_G388_L0.8120.58
385_R388_L0.8120.58
427_R796_F0.8110.58
422_Q463_N0.8110.58
530_V539_I0.8110.58
422_Q461_E0.8110.58
118_Y133_T0.8090.58
160_K205_E0.8090.58
82_I87_V0.8080.58
334_I844_E0.8080.58
750_Q800_A0.8060.57
510_T588_I0.8060.57
603_I740_I0.8050.57
116_R479_I0.8040.57
98_C780_G0.8020.57
588_I598_F0.8010.57
686_P697_E0.8000.57
363_Q381_P0.7990.57
600_K604_G0.7980.57
615_L624_G0.7980.57
70_G98_C0.7960.56
582_H590_N0.7960.56
251_E257_A0.7930.56
414_G436_R0.7920.56
536_E539_I0.7910.56
613_H617_K0.7890.56
98_C149_C0.7880.56
708_R711_A0.7860.55
723_N728_M0.7850.55
326_I455_A0.7840.55
804_E811_V0.7830.55
537_P546_Y0.7830.55
26_A59_P0.7830.55
610_S720_D0.7820.55
342_I495_I0.7810.55
80_P94_L0.7800.55
519_E522_Q0.7800.55
734_R825_N0.7800.55
604_G730_R0.7770.55
553_S593_L0.7760.55
90_I277_F0.7760.55
77_L80_P0.7750.54
843_G846_V0.7750.54
379_I385_R0.7750.54
224_M378_V0.7740.54
212_L273_V0.7730.54
149_C154_Y0.7730.54
165_Y168_R0.7730.54
121_I128_A0.7730.54
24_V611_I0.7720.54
243_V477_K0.7720.54
223_I231_A0.7720.54
248_R268_L0.7720.54
537_P547_T0.7720.54
115_S119_N0.7710.54
541_A546_Y0.7710.54
407_I410_H0.7700.54
419_F443_F0.7690.54
111_I158_L0.7670.54
579_D586_V0.7670.54
531_K535_G0.7670.54
157_K160_K0.7660.54
86_L703_T0.7660.54
132_L147_P0.7640.53
813_T821_R0.7630.53
324_T443_F0.7630.53
168_R172_V0.7630.53
224_M694_E0.7620.53
615_L623_Y0.7610.53
496_I502_Y0.7610.53
113_K157_K0.7610.53
308_R312_N0.7600.53
860_S863_G0.7600.53
256_G694_E0.7590.53
452_P496_I0.7580.53
805_G818_Y0.7570.53
512_K544_E0.7570.53
546_Y580_C0.7550.52
60_T70_G0.7550.52
473_I476_A0.7550.52
355_P397_L0.7530.52
706_K709_S0.7500.52
144_Q243_V0.7490.52
431_M453_Y0.7490.52
582_H591_G0.7490.52
805_G809_T0.7480.52
358_I379_I0.7470.52
538_A550_Q0.7460.52
542_P549_K0.7460.52
306_E311_G0.7460.52
588_I594_L0.7460.52
847_Q853_D0.7460.52
505_G527_V0.7460.52
863_G867_D0.7460.52
505_G824_I0.7450.52
589_K595_E0.7450.52
82_I184_L0.7450.52
285_P290_R0.7440.51
525_L528_A0.7440.51
222_S230_R0.7440.51
241_D244_R0.7440.51
510_T545_Y0.7440.51
135_Y147_P0.7430.51
245_I272_H0.7410.51
500_Q605_N0.7400.51
84_V105_K0.7400.51
729_A737_V0.7380.51
360_K411_L0.7370.51
305_K425_L0.7360.51
253_I256_G0.7320.50
615_L787_R0.7320.50
46_D50_G0.7320.50
382_D405_Y0.7310.50
504_S727_V0.7300.50
363_Q666_D0.7300.50
18_E418_L0.7290.50
577_N584_S0.7290.50
591_G596_G0.7290.50
69_P72_F0.7280.50
373_P604_G0.7280.50
602_A713_D0.7270.50
373_P437_V0.7260.50
268_L271_Y0.7260.50
154_Y159_E0.7260.50
470_E853_D0.7260.50
47_P358_I0.7250.50
222_S232_E0.7230.49
53_E816_S0.7220.49
538_A604_G0.7210.49
23_S49_L0.7200.49
507_Y727_V0.7200.49
116_R119_N0.7200.49
113_K146_C0.7180.49
16_P211_V0.7180.49
238_K268_L0.7170.49
562_F584_S0.7170.49
9_I208_I0.7170.49
461_E828_S0.7160.49
308_R313_L0.7160.49
505_G635_F0.7150.49
51_V217_I0.7130.48
723_N812_R0.7130.48
671_E699_Y0.7120.48
310_R425_L0.7110.48
820_Q825_N0.7110.48
121_I129_A0.7110.48
594_L597_V0.7110.48
105_K208_I0.7100.48
591_G598_F0.7090.48
245_I248_R0.7080.48
859_Y863_G0.7070.48
19_I197_Y0.7070.48
305_K813_T0.7060.48
395_K418_L0.7060.48
113_K116_R0.7060.48
472_A682_G0.7050.48
507_Y730_R0.7050.48
98_C180_I0.7050.48
594_L598_F0.7040.48
847_Q854_G0.7040.48
160_K397_L0.7040.48
809_T818_Y0.7030.47
542_P545_Y0.7030.47
278_D332_I0.7030.47
82_I98_C0.7020.47
497_G599_D0.7020.47
258_P261_I0.7020.47
752_V780_G0.7010.47
34_D49_L0.7010.47
470_E476_A0.7010.47
93_F124_R0.7010.47
258_P265_L0.7000.47
548_G596_G0.6980.47
128_A131_R0.6980.47
307_G315_G0.6970.47
222_S233_D0.6970.47
78_V107_S0.6960.47
249_L682_G0.6960.47
429_S491_Y0.6940.47
494_P805_G0.6940.47
113_K118_Y0.6930.46
185_E362_R0.6930.46
728_M735_G0.6930.46
149_C157_K0.6920.46
736_S741_T0.6900.46
553_S561_N0.6900.46
322_S466_V0.6890.46
813_T817_G0.6890.46
847_Q858_M0.6890.46
185_E205_E0.6890.46
271_Y275_T0.6880.46
483_H622_E0.6880.46
42_G453_Y0.6850.46
56_Q65_L0.6840.46
812_R825_N0.6830.46
375_A407_I0.6820.45
305_K310_R0.6820.45
277_F776_P0.6820.45
513_T542_P0.6800.45
37_G224_M0.6800.45
131_R134_E0.6780.45
302_L309_F0.6780.45
553_S556_L0.6780.45
168_R171_G0.6780.45
797_F834_Y0.6780.45
603_I608_P0.6770.45
60_T71_H0.6770.45
433_H482_V0.6760.45
588_I595_E0.6750.45
346_T775_S0.6750.45
656_D663_N0.6750.45
524_I553_S0.6740.45
589_K596_G0.6740.45
805_G820_Q0.6730.45
560_F795_L0.6720.44
557_P562_F0.6720.44
310_R454_N0.6700.44
585_Y590_N0.6700.44
93_F551_V0.6700.44
817_G821_R0.6690.44
105_K496_I0.6680.44
780_G847_Q0.6670.44
377_Y393_D0.6670.44
112_E116_R0.6660.44
212_L516_L0.6650.44
486_I496_I0.6650.44
214_V362_R0.6650.44
518_K521_A0.6640.44
343_I466_V0.6640.44
127_S131_R0.6640.44
548_G555_F0.6640.44
850_Y854_G0.6640.44
712_G736_S0.6630.44
55_G64_T0.6630.44
795_L806_L0.6630.44
595_E603_I0.6630.44
209_L394_R0.6620.44
582_H595_E0.6620.44
126_P133_T0.6610.43
780_G815_Q0.6610.43
419_F464_L0.6610.43
97_T184_L0.6600.43
53_E65_L0.6590.43
490_R600_K0.6590.43
419_F462_M0.6580.43
373_P780_G0.6580.43
715_A726_Y0.6580.43
175_L178_S0.6580.43
578_E588_I0.6570.43
118_Y124_R0.6560.43
120_A133_T0.6550.43
164_F194_I0.6550.43
711_A746_M0.6550.43
645_T649_E0.6530.43
53_E66_G0.6520.43
54_P429_S0.6510.42
357_N752_V0.6500.42
42_G48_R0.6500.42
545_Y553_S0.6490.42
223_I234_D0.6490.42
113_K120_A0.6480.42
513_T722_F0.6480.42
127_S134_E0.6480.42
309_F450_C0.6470.42
753_R799_A0.6470.42
113_K122_K0.6470.42
145_V152_K0.6470.42
578_E583_D0.6460.42
534_L541_A0.6460.42
653_L725_A0.6450.42
380_R826_A0.6450.42
120_A128_A0.6440.42
182_E185_E0.6440.42
559_D562_F0.6440.42
53_E794_E0.6420.42
343_I347_L0.6410.42
714_I717_K0.6400.41
710_T714_I0.6390.41
452_P782_I0.6390.41
588_I615_L0.6380.41
39_P270_Q0.6370.41
16_P210_T0.6360.41
307_G425_L0.6350.41
238_K271_Y0.6350.41
36_D64_T0.6350.41
510_T796_F0.6340.41
488_T780_G0.6330.41
184_L187_I0.6320.41
118_Y129_A0.6310.41
652_S720_D0.6300.40
38_T44_V0.6300.40
428_I452_P0.6300.40
578_E581_P0.6290.40
556_L562_F0.6270.40
172_V195_L0.6270.40
117_I127_S0.6270.40
227_S242_I0.6270.40
22_M29_T0.6260.40
500_Q735_G0.6250.40
611_I627_L0.6250.40
556_L559_D0.6250.40
271_Y284_L0.6240.40
599_D638_F0.6240.40
235_L308_R0.6230.40
265_L289_H0.6220.40
646_M799_A0.6220.40
54_P850_Y0.6210.40
479_I625_K0.6200.40
347_L735_G0.6200.40
222_S780_G0.6200.40
627_L638_F0.6190.39
712_G716_S0.6190.39
224_M229_I0.6190.39
490_R739_N0.6190.39
500_Q812_R0.6180.39
546_Y583_D0.6180.39
264_D268_L0.6170.39
745_A790_L0.6170.39
106_I114_Y0.6150.39
47_P59_P0.6150.39
503_I603_I0.6150.39
175_L522_Q0.6150.39
416_I424_S0.6140.39
529_D533_D0.6140.39
193_E814_S0.6130.39
520_E543_R0.6130.39
496_I630_N0.6130.39
503_I506_A0.6130.39
555_F630_N0.6130.39
268_L319_D0.6120.39
22_M25_T0.6120.39
96_A105_K0.6110.39
154_Y158_L0.6110.39
246_N250_K0.6110.39
814_S818_Y0.6100.39
82_I101_C0.6100.39
248_R258_P0.6090.39
335_D625_K0.6090.39
506_A631_L0.6080.38
809_T812_R0.6080.38
865_T868_V0.6070.38
252_S265_L0.6070.38
448_L498_A0.6060.38
589_K599_D0.6060.38
60_T98_C0.6060.38
490_R750_Q0.6060.38
715_A740_I0.6050.38
436_R853_D0.6050.38
653_L787_R0.6050.38
712_G806_L0.6050.38
500_Q542_P0.6040.38
435_V682_G0.6040.38
698_N782_I0.6030.38
277_F721_P0.6030.38
13_I673_D0.6010.38
327_S442_T0.6000.38
6_I11_F0.5990.38
461_E825_N0.5990.38
610_S641_L0.5980.38
808_D821_R0.5970.37
510_T586_V0.5970.37
839_R843_G0.5970.37
655_D670_V0.5970.37
835_D838_V0.5960.37
13_I298_L0.5960.37
373_P647_R0.5960.37
625_K631_L0.5950.37
676_I696_L0.5950.37
780_G851_G0.5950.37
90_I180_I0.5940.37
715_A745_A0.5940.37
776_P780_G0.5940.37
128_A132_L0.5940.37
108_E148_H0.5930.37
374_G532_I0.5920.37
812_R815_Q0.5920.37
645_T730_R0.5910.37
199_P506_A0.5910.37
503_I638_F0.5900.37
623_Y699_Y0.5900.37
622_E626_W0.5890.37
548_G562_F0.5890.37
697_E701_L0.5880.37
79_R266_W0.5870.37
243_V333_S0.5870.37
37_G230_R0.5870.37
866_V869_N0.5870.37
752_V774_I0.5860.36
645_T751_S0.5860.36
707_L812_R0.5840.36
183_R869_N0.5840.36
473_I785_S0.5840.36
696_L700_I0.5840.36
388_L644_F0.5830.36
298_L625_K0.5830.36
645_T736_S0.5830.36
322_S353_I0.5830.36
395_K444_R0.5820.36
583_D596_G0.5820.36
126_P143_A0.5820.36
644_F855_V0.5820.36
588_I596_G0.5810.36
685_E699_Y0.5810.36
559_D563_H0.5810.36
493_G496_I0.5810.36
746_M781_F0.5800.36
632_F636_I0.5800.36
586_V615_L0.5790.36
375_A604_G0.5780.36
223_I296_R0.5760.36
715_A719_L0.5760.36
487_I829_D0.5760.36
205_E656_D0.5750.35
250_K254_D0.5740.35
303_K606_Q0.5740.35
314_S498_A0.5730.35
521_A525_L0.5720.35
422_Q425_L0.5720.35
654_G718_Y0.5720.35
242_I287_S0.5720.35
730_R737_V0.5710.35
513_T540_L0.5710.35
226_E229_I0.5710.35
242_I838_V0.5700.35
410_H780_G0.5700.35
541_A547_T0.5700.35
19_I213_P0.5700.35
287_S477_K0.5700.35
113_K127_S0.5690.35
381_P388_L0.5690.35
491_Y603_I0.5690.35
444_R799_A0.5680.35
171_G187_I0.5680.35
549_K591_G0.5680.35
88_K430_M0.5680.35
117_I120_A0.5680.35
708_R739_N0.5670.35
104_V195_L0.5660.35
655_D680_K0.5660.35
587_V868_V0.5660.35
564_G602_A0.5650.35
197_Y249_L0.5650.35
623_Y627_L0.5650.35
543_R547_T0.5640.35
535_G538_A0.5640.35
863_G868_V0.5630.34
145_V171_G0.5630.34
537_P540_L0.5620.34
185_E477_K0.5620.34
581_P595_E0.5620.34
254_D257_A0.5620.34
108_E222_S0.5610.34
548_G739_N0.5610.34
542_P547_T0.5610.34
545_Y549_K0.5600.34
46_D337_V0.5600.34
675_L722_F0.5600.34
249_L258_P0.5590.34
503_I535_G0.5590.34
194_I198_D0.5590.34
549_K812_R0.5590.34
361_L412_I0.5580.34
119_N125_W0.5570.34
780_G839_R0.5570.34
261_I265_L0.5570.34
18_E794_E0.5560.34
808_D814_S0.5560.34
241_D281_I0.5560.34
34_D69_P0.5550.34
580_C584_S0.5550.34
721_P863_G0.5550.34
20_R24_V0.5540.34
435_V642_Q0.5540.34
86_L722_F0.5540.34
295_L801_G0.5530.34
843_G869_N0.5530.34
229_I240_V0.5530.34
225_I382_D0.5520.33
308_R320_F0.5520.33
356_W432_A0.5520.33
380_R386_I0.5520.33
51_V267_D0.5520.33
786_F792_P0.5510.33
496_I780_G0.5510.33
466_V842_Y0.5500.33
240_V265_L0.5500.33
93_F168_R0.5490.33
259_Q263_E0.5490.33
164_F168_R0.5490.33
449_V453_Y0.5490.33
318_V462_M0.5480.33
57_K64_T0.5480.33
373_P853_D0.5480.33
552_I713_D0.5470.33
555_F611_I0.5470.33
307_G818_Y0.5470.33
560_F565_Q0.5460.33
596_G739_N0.5460.33
83_H471_E0.5460.33
647_R725_A0.5450.33
453_Y647_R0.5450.33
32_V264_D0.5430.33
619_Y721_P0.5430.33
373_P856_F0.5430.33
521_A535_G0.5430.33
99_R284_L0.5430.33
222_S301_R0.5420.33
812_R818_Y0.5420.33
627_L787_R0.5420.33
599_D602_A0.5420.33
556_L848_V0.5420.33
519_E523_Q0.5420.33
742_Q801_G0.5410.33
556_L619_Y0.5400.32
159_E435_V0.5400.32
333_S633_R0.5400.32
447_L632_F0.5400.32
456_D459_G0.5390.32
376_N384_R0.5390.32
335_D639_V0.5390.32
261_I268_L0.5390.32
50_G58_C0.5390.32
117_I128_A0.5380.32
496_I611_I0.5380.32
330_P742_Q0.5380.32
695_S725_A0.5380.32
222_S694_E0.5380.32
840_S868_V0.5370.32
241_D264_D0.5370.32
333_S336_E0.5360.32
511_V721_P0.5360.32
279_N293_R0.5360.32
477_K484_K0.5360.32
240_V258_P0.5360.32
620_S851_G0.5350.32
616_I620_S0.5350.32
213_P355_P0.5350.32
100_R151_E0.5330.32
803_R817_G0.5330.32
784_S790_L0.5320.32
752_V822_R0.5320.32
357_N474_A0.5310.32
167_E172_V0.5310.32
523_Q546_Y0.5310.32
209_L298_L0.5310.32
314_S825_N0.5310.32
122_K127_S0.5310.32
6_I386_I0.5300.32
209_L248_R0.5300.32
313_L428_I0.5300.32
320_F408_E0.5300.32
16_P20_R0.5300.32
427_R485_N0.5300.32
314_S447_L0.5290.32
38_T67_N0.5290.32
121_I132_L0.5280.31
663_N680_K0.5280.31
43_S46_D0.5270.31
712_G737_V0.5270.31
311_G715_A0.5270.31
11_F407_I0.5270.31
453_Y462_M0.5270.31
44_V75_I0.5260.31
557_P584_S0.5260.31
589_K597_V0.5260.31
228_G231_A0.5260.31
165_Y259_Q0.5250.31
486_I624_G0.5250.31
167_E291_S0.5250.31
534_L583_D0.5250.31
106_I112_E0.5250.31
194_I713_D0.5250.31
847_Q851_G0.5240.31
219_I447_L0.5240.31
281_I285_P0.5240.31
68_C73_G0.5240.31
446_N733_A0.5240.31
41_E722_F0.5230.31
90_I536_E0.5230.31
827_L837_T0.5230.31
322_S443_F0.5220.31
728_M734_R0.5220.31
318_V433_H0.5220.31
414_G538_A0.5210.31
646_M740_I0.5210.31
326_I462_M0.5210.31
305_K454_N0.5200.31
694_E702_D0.5200.31
376_N385_R0.5200.31
533_D541_A0.5200.31
237_H240_V0.5190.31
425_L813_T0.5190.31
579_D582_H0.5190.31
646_M791_K0.5190.31
103_R472_A0.5180.31
560_F563_H0.5180.31
409_R415_D0.5180.31
419_F508_L0.5180.31
428_I487_I0.5180.31
149_C696_L0.5170.31
47_P52_I0.5170.31
450_C492_G0.5160.30
747_L785_S0.5160.30
748_G789_G0.5160.30
118_Y136_V0.5160.30
846_V850_Y0.5150.30
699_Y703_T0.5140.30
707_L722_F0.5140.30
774_I807_V0.5140.30
331_N637_R0.5140.30
387_D858_M0.5130.30
678_K684_L0.5130.30
513_T653_L0.5130.30
407_I474_A0.5120.30
357_N834_Y0.5120.30
565_Q855_V0.5120.30
79_R411_L0.5120.30
735_G809_T0.5110.30
118_Y127_S0.5110.30
247_E250_K0.5110.30
383_G464_L0.5110.30
484_K716_S0.5100.30
517_T522_Q0.5100.30
546_Y556_L0.5100.30
49_L63_N0.5100.30
335_D629_D0.5100.30
577_N586_V0.5100.30
161_P170_E0.5100.30
611_I799_A0.5100.30
277_F707_L0.5090.30
213_P324_T0.5090.30
141_M145_V0.5090.30
359_E362_R0.5090.30
752_V839_R0.5090.30
414_G506_A0.5090.30
177_P266_W0.5080.30
437_V502_Y0.5080.30
380_R383_G0.5080.30
88_K253_I0.5080.30
465_H808_D0.5080.30
591_G604_G0.5070.30
282_P376_N0.5070.30
224_M256_G0.5070.30
115_S118_Y0.5070.30
514_T544_E0.5070.30
56_Q59_P0.5070.30
548_G812_R0.5060.30
512_K542_P0.5060.30
280_E291_S0.5060.30
243_V382_D0.5050.30
839_R847_Q0.5050.30
709_S712_G0.5040.29
648_L668_A0.5040.29
648_L651_V0.5030.29
361_L441_L0.5030.29
160_K163_N0.5030.29
207_M449_V0.5030.29
105_K469_S0.5020.29
802_G828_S0.5020.29
585_Y598_F0.5020.29
337_V464_L0.5010.29
490_R493_G0.5010.29
796_F799_A0.5000.29
447_L635_F0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4aybA 1 0.9909 100 0.04 Contact Map
4qiwA 2 0.967 100 0.053 Contact Map
3h0gA 2 0.9807 100 0.067 Contact Map
1twfA 1 0.9807 100 0.068 Contact Map
4c2mA 1 0.983 100 0.072 Contact Map
4yfkD 1 0.892 100 0.26 Contact Map
1hqmD 1 0.8375 100 0.27 Contact Map
2a6hD 1 0.9068 100 0.304 Contact Map
3qqcA 1 0.3591 100 0.681 Contact Map
1yelA 1 0.1125 27.6 0.989 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0193 seconds.