GREMLIN Database
Q980R1 - DNA-directed RNA polymerase
UniProt: Q980R1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 649 (594)
Sequences: 2219 (862)
Seq/√Len: 35.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
250_A431_P8.2311.00
483_L489_P4.6011.00
139_E164_H4.5501.00
435_L439_A4.3581.00
227_L458_A4.1981.00
141_L149_A4.0591.00
268_S432_D3.8791.00
248_I512_V3.6531.00
251_V513_V3.5781.00
212_R223_P3.5011.00
279_F365_R3.4651.00
265_M413_I3.4401.00
228_V455_G3.4361.00
329_V335_L3.4161.00
298_I387_V3.4001.00
403_F515_Y3.2791.00
264_I434_I3.2301.00
265_M397_P3.2151.00
480_N484_R3.2001.00
262_S492_T3.1991.00
252_M508_I3.1011.00
340_S360_T3.1001.00
318_E324_S3.0261.00
377_I385_K2.9521.00
627_Q630_M2.8821.00
64_K68_R2.8731.00
474_P477_Q2.8421.00
622_F626_I2.7921.00
495_V510_F2.7841.00
452_G513_V2.7641.00
208_N245_N2.7181.00
268_S272_R2.7151.00
264_I415_M2.6901.00
158_L162_H2.6741.00
494_V503_K2.6421.00
108_S113_L2.6291.00
117_E123_E2.6201.00
247_A275_Y2.6001.00
271_E419_Q2.5881.00
461_S485_Y2.5841.00
626_I636_P2.5821.00
395_R524_D2.5251.00
370_G391_V2.4611.00
377_I387_V2.4541.00
329_V372_V2.4231.00
299_V339_V2.3791.00
114_V137_K2.3651.00
425_T510_F2.3570.99
118_D137_K2.3070.99
529_R532_G2.3050.99
270_V416_L2.2970.99
481_E484_R2.2820.99
269_S397_P2.2320.99
476_E480_N2.2120.99
57_D60_E2.2080.99
494_V507_R2.1910.99
330_K369_M2.1410.99
496_Y503_K2.1130.99
110_G122_L2.1060.99
316_L323_V2.1050.99
425_T429_V2.0930.99
115_T123_E2.0890.99
521_M524_D2.0450.99
60_E67_E2.0440.99
456_K493_E2.0420.99
571_K576_D1.9750.98
298_I322_V1.9460.98
324_S327_V1.9400.98
196_A199_K1.9390.98
282_L388_K1.9380.98
450_M475_I1.9300.98
105_I112_P1.9290.98
29_V32_G1.9180.98
373_D392_R1.9180.98
450_M453_I1.9070.98
249_L452_G1.9050.98
45_V49_G1.8750.97
38_E45_V1.8740.97
576_D594_W1.8620.97
250_A495_V1.8540.97
152_A158_L1.8510.97
253_S434_I1.8480.97
127_I135_Q1.8410.97
275_Y403_F1.8220.97
187_Q193_Y1.7950.97
188_S193_Y1.7930.97
283_Y391_V1.7870.97
264_I417_I1.7720.96
121_K127_I1.7690.96
398_T523_A1.7540.96
249_L513_V1.7520.96
431_P508_I1.7520.96
364_T391_V1.7120.96
453_I509_Y1.6910.95
38_E41_K1.6890.95
149_A163_T1.6880.95
116_I120_E1.6750.95
553_F573_R1.6510.95
189_P193_Y1.6400.94
425_T495_V1.6330.94
106_I109_N1.6300.94
89_N109_N1.6270.94
60_E64_K1.6070.94
290_Y296_D1.6030.94
34_E39_Y1.6000.94
457_Y461_S1.5900.93
255_T499_R1.5870.93
187_Q191_N1.5820.93
79_N88_I1.5590.93
482_I491_A1.5590.93
480_N483_L1.5480.92
66_R105_I1.5450.92
159_T162_H1.5410.92
490_D507_R1.5350.92
424_Y496_Y1.5320.92
404_A448_Q1.5070.91
456_K487_Y1.5030.91
427_K487_Y1.5000.91
335_L372_V1.4920.91
221_H278_T1.4790.91
582_M615_P1.4780.90
111_N116_I1.4670.90
268_S419_Q1.4650.90
111_N124_S1.4540.90
539_R620_Y1.4540.90
459_A512_V1.4510.90
111_N115_T1.4470.90
395_R521_M1.4450.89
89_N108_S1.4450.89
187_Q194_Q1.4380.89
606_I614_F1.4290.89
191_N194_Q1.4230.89
111_N120_E1.4110.88
266_N419_Q1.4090.88
89_N101_R1.3920.88
630_M636_P1.3860.87
56_Q68_R1.3770.87
59_G64_K1.3730.87
413_I434_I1.3720.87
110_G114_V1.3620.86
277_S517_K1.3580.86
229_Q234_D1.3540.86
348_F351_L1.3520.86
55_Y58_G1.3480.86
344_F349_K1.3480.86
106_I372_V1.3400.86
173_L469_P1.3300.85
337_G361_S1.3220.85
65_I530_A1.3110.84
325_P375_V1.3080.84
247_A269_S1.3060.84
174_G177_A1.3040.84
395_R447_G1.2980.84
382_E434_I1.2950.84
336_I362_I1.2880.83
285_T336_I1.2840.83
465_V481_E1.2840.83
580_R617_T1.2760.83
287_E387_V1.2740.82
177_A388_K1.2730.82
517_K632_M1.2650.82
276_R396_I1.2610.82
134_R158_L1.2570.82
193_Y197_M1.2540.81
252_M433_I1.2540.81
482_I487_Y1.2470.81
572_D577_N1.2450.81
287_E298_I1.2390.81
406_R552_R1.2330.80
426_V493_E1.2230.80
54_Y63_N1.2200.80
320_N375_V1.2150.79
512_V526_L1.2130.79
529_R550_G1.2040.79
177_A255_T1.2030.79
447_G451_E1.1990.78
251_V452_G1.1990.78
622_F638_L1.1910.78
110_G115_T1.1900.78
250_A508_I1.1900.78
393_D492_T1.1870.78
112_P115_T1.1830.77
348_F352_S1.1760.77
172_I618_V1.1720.77
25_V28_R1.1710.77
379_E531_R1.1700.77
593_G605_P1.1690.77
192_T196_A1.1680.77
129_F132_L1.1680.77
408_G451_E1.1620.76
62_A91_V1.1610.76
139_E145_E1.1600.76
472_K477_Q1.1590.76
412_V450_M1.1590.76
478_L481_E1.1450.75
558_R562_I1.1450.75
154_E157_D1.1430.75
605_P609_D1.1420.75
29_V36_Q1.1410.75
67_E71_K1.1390.75
591_Y635_S1.1380.75
141_L286_E1.1370.75
458_A465_V1.1370.75
117_E120_E1.1360.75
457_Y485_Y1.1340.74
115_T120_E1.1330.74
247_A433_I1.1310.74
573_R607_H1.1300.74
180_I227_L1.1290.74
285_T362_I1.1290.74
475_I479_Q1.1250.74
128_T164_H1.1240.74
105_I165_L1.1230.74
71_K100_V1.1220.74
450_M478_L1.1210.74
65_I382_E1.1160.73
275_Y397_P1.1150.73
513_V516_Q1.1150.73
444_M544_G1.1130.73
28_R36_Q1.1020.72
537_L631_S1.1010.72
535_Q542_T1.1010.72
467_A473_T1.0990.72
111_N114_V1.0920.72
197_M444_M1.0880.71
594_W614_F1.0870.71
194_Q516_Q1.0830.71
120_E124_S1.0810.71
290_Y293_G1.0810.71
351_L355_Q1.0800.71
24_E30_T1.0800.71
37_N573_R1.0790.71
95_C99_R1.0770.70
152_A165_L1.0770.70
454_A478_L1.0730.70
340_S353_P1.0680.70
269_S274_M1.0670.70
205_Y404_A1.0660.70
527_H543_E1.0640.70
145_E164_H1.0620.69
329_V364_T1.0600.69
110_G113_L1.0600.69
79_N619_S1.0590.69
259_M262_S1.0530.69
406_R451_E1.0530.69
444_M552_R1.0520.69
258_N337_G1.0510.69
194_Q198_A1.0470.68
67_E108_S1.0460.68
56_Q60_E1.0450.68
403_F436_N1.0430.68
263_I403_F1.0400.68
431_P515_Y1.0390.68
24_E38_E1.0370.68
188_S191_N1.0350.67
157_D160_P1.0350.67
458_A481_E1.0350.67
151_V169_S1.0340.67
398_T416_L1.0310.67
250_A434_I1.0310.67
179_I241_R1.0290.67
39_Y95_C1.0270.67
57_D68_R1.0250.67
38_E42_W1.0230.66
52_I372_V1.0210.66
250_A432_D1.0190.66
39_Y42_W1.0180.66
186_N447_G1.0170.66
283_Y368_E1.0120.66
27_R30_T1.0110.66
247_A274_M1.0110.66
110_G120_E1.0100.65
128_T139_E1.0060.65
189_P197_M1.0040.65
23_E28_R1.0030.65
473_T478_L1.0030.65
143_A420_V1.0020.65
114_V118_D1.0020.65
328_E369_M1.0000.65
431_P495_V0.9990.65
60_E109_N0.9980.64
207_A245_N0.9960.64
532_G550_G0.9960.64
269_S623_K0.9950.64
114_V120_E0.9950.64
112_P118_D0.9950.64
354_E357_K0.9940.64
544_G552_R0.9930.64
156_N165_L0.9930.64
573_R594_W0.9870.64
293_G341_P0.9860.64
312_E315_R0.9850.63
316_L333_D0.9830.63
408_G447_G0.9820.63
60_E89_N0.9810.63
336_I387_V0.9800.63
186_N451_E0.9760.63
419_Q430_V0.9750.63
162_H433_I0.9710.62
317_L429_V0.9710.62
269_S422_M0.9680.62
553_F574_L0.9650.62
220_L631_S0.9630.62
322_V495_V0.9620.62
547_R562_I0.9620.62
480_N489_P0.9590.61
431_P434_I0.9580.61
63_N67_E0.9560.61
62_A106_I0.9560.61
452_G509_Y0.9550.61
118_D122_L0.9550.61
60_E68_R0.9520.61
270_V433_I0.9510.61
116_I119_I0.9500.61
364_T367_G0.9480.60
52_I60_E0.9430.60
453_I513_V0.9350.59
61_L335_L0.9300.59
30_T37_N0.9290.59
267_R271_E0.9290.59
407_H447_G0.9250.59
185_H414_G0.9210.58
26_I30_T0.9210.58
23_E27_R0.9190.58
460_L485_Y0.9190.58
65_I124_S0.9160.58
622_F636_P0.9130.58
251_V486_G0.9130.58
29_V35_D0.9120.57
23_E34_E0.9120.57
25_V29_V0.9120.57
121_K126_A0.9090.57
320_N385_K0.9070.57
60_E63_N0.9070.57
117_E121_K0.9060.57
271_E320_N0.9050.57
57_D89_N0.9030.57
71_K109_N0.9020.57
197_M442_S0.9020.57
450_M454_A0.9010.57
54_Y67_E0.9000.56
293_G340_S0.8990.56
544_G549_G0.8950.56
248_I425_T0.8940.56
558_R573_R0.8930.56
379_E385_K0.8930.56
576_D580_R0.8930.56
122_L373_D0.8920.56
142_D346_Q0.8920.56
23_E39_Y0.8910.56
304_G310_G0.8910.56
525_K529_R0.8910.56
112_P116_I0.8900.56
68_R73_E0.8850.55
151_V367_G0.8850.55
483_L487_Y0.8770.54
322_V377_I0.8750.54
278_T392_R0.8750.54
138_I161_D0.8740.54
225_R389_V0.8730.54
406_R544_G0.8720.54
242_P422_M0.8700.54
581_T626_I0.8690.54
89_N106_I0.8690.54
625_L628_E0.8660.54
109_N113_L0.8640.53
349_K352_S0.8640.53
439_A458_A0.8610.53
177_A546_A0.8600.53
531_R535_Q0.8580.53
141_L164_H0.8580.53
23_E29_V0.8560.53
357_K360_T0.8560.53
625_L629_L0.8550.53
520_H525_K0.8540.53
623_K627_Q0.8540.53
186_N408_G0.8540.53
404_A435_L0.8540.53
509_Y513_V0.8540.53
249_L537_L0.8530.52
298_I377_I0.8530.52
449_I452_G0.8520.52
433_I464_I0.8510.52
115_T118_D0.8510.52
415_M421_D0.8490.52
24_E36_Q0.8470.52
197_M544_G0.8470.52
281_R482_I0.8460.52
115_T122_L0.8440.52
245_N274_M0.8430.52
112_P120_E0.8430.52
486_G496_Y0.8420.51
424_Y486_G0.8420.51
581_T627_Q0.8400.51
286_E386_L0.8380.51
77_E101_R0.8350.51
249_L274_M0.8350.51
195_S258_N0.8350.51
327_V338_K0.8340.51
434_I509_Y0.8340.51
272_R515_Y0.8300.50
36_Q41_K0.8290.50
24_E28_R0.8270.50
27_R38_E0.8270.50
79_N101_R0.8230.50
240_N530_A0.8230.50
566_T574_L0.8230.50
262_S561_L0.8210.50
346_Q352_S0.8150.49
101_R109_N0.8130.49
186_N543_E0.8080.49
257_Y441_P0.8080.49
311_K353_P0.8070.48
255_T264_I0.8060.48
189_P521_M0.8050.48
406_R444_M0.8040.48
23_E33_G0.8030.48
316_L324_S0.8030.48
24_E27_R0.8020.48
329_V333_D0.8020.48
57_D63_N0.8020.48
138_I149_A0.8010.48
144_E492_T0.8000.48
368_E521_M0.8000.48
328_E371_I0.8000.48
545_R564_F0.7990.48
299_V303_A0.7990.48
252_M282_L0.7970.48
104_L107_V0.7970.48
452_G511_G0.7970.48
59_G63_N0.7950.47
60_E66_R0.7950.47
379_E383_G0.7910.47
448_Q455_G0.7890.47
30_T36_Q0.7870.47
554_G557_E0.7850.47
131_D463_N0.7850.47
436_N449_I0.7840.46
247_A432_D0.7840.46
32_G36_Q0.7830.46
540_Q549_G0.7820.46
140_Y434_I0.7810.46
264_I403_F0.7800.46
36_Q40_L0.7790.46
263_I515_Y0.7760.46
197_M552_R0.7760.46
44_K264_I0.7760.46
147_E287_E0.7710.45
151_V165_L0.7710.45
65_I80_V0.7670.45
434_I512_V0.7670.45
593_G613_L0.7660.45
620_Y627_Q0.7650.45
254_F499_R0.7630.45
189_P199_K0.7630.45
207_A240_N0.7620.45
571_K616_V0.7610.45
180_I183_P0.7600.44
287_E385_K0.7600.44
609_D634_I0.7590.44
520_H529_R0.7590.44
391_V424_Y0.7580.44
248_I431_P0.7570.44
267_R418_P0.7570.44
373_D403_F0.7570.44
158_L165_L0.7550.44
74_I288_V0.7550.44
32_G382_E0.7540.44
291_P296_D0.7540.44
522_V538_T0.7520.44
64_K108_S0.7490.43
149_A164_H0.7480.43
621_A628_E0.7460.43
188_S263_I0.7450.43
177_A357_K0.7450.43
262_S286_E0.7440.43
23_E30_T0.7440.43
111_N117_E0.7430.43
101_R107_V0.7420.43
397_P521_M0.7410.43
25_V31_E0.7410.43
310_G315_R0.7410.43
44_K55_Y0.7350.42
53_G119_I0.7340.42
559_D573_R0.7330.42
27_R32_G0.7320.42
290_Y542_T0.7320.42
155_P165_L0.7310.42
23_E32_G0.7300.42
91_V472_K0.7300.42
188_S194_Q0.7300.42
346_Q546_A0.7300.42
244_G555_E0.7290.42
179_I253_S0.7260.42
433_I455_G0.7250.41
300_M304_G0.7240.41
296_D458_A0.7230.41
172_I561_L0.7220.41
342_P380_T0.7210.41
435_L448_Q0.7200.41
58_G67_E0.7200.41
35_D39_Y0.7200.41
389_V547_R0.7180.41
57_D64_K0.7180.41
291_P343_R0.7150.41
516_Q573_R0.7150.41
40_L436_N0.7140.41
533_P538_T0.7130.40
150_Y165_L0.7130.40
515_Y623_K0.7120.40
558_R561_L0.7120.40
265_M526_L0.7110.40
496_Y507_R0.7090.40
44_K258_N0.7090.40
543_E590_G0.7080.40
136_G325_P0.7070.40
204_L277_S0.7050.40
408_G552_R0.7050.40
561_L573_R0.7040.40
413_I433_I0.7030.40
272_R431_P0.7020.40
34_E37_N0.7020.40
145_E227_L0.7010.39
628_E632_M0.6990.39
487_Y610_K0.6990.39
526_L545_R0.6990.39
262_S399_I0.6990.39
349_K356_A0.6980.39
109_N120_E0.6970.39
549_G554_G0.6970.39
191_N516_Q0.6940.39
40_L122_L0.6940.39
458_A461_S0.6940.39
383_G397_P0.6940.39
488_L507_R0.6940.39
23_E26_I0.6930.39
144_E627_Q0.6920.39
65_I248_I0.6910.39
89_N107_V0.6910.39
527_H544_G0.6910.39
67_E106_I0.6910.39
173_L183_P0.6910.39
201_A205_Y0.6890.38
403_F537_L0.6890.38
36_Q195_S0.6880.38
581_T620_Y0.6870.38
339_V359_D0.6870.38
316_L327_V0.6860.38
183_P243_A0.6860.38
407_H451_E0.6820.38
409_Q445_T0.6760.37
176_T573_R0.6760.37
474_P478_L0.6760.37
175_I553_F0.6740.37
86_D97_S0.6740.37
322_V336_I0.6720.37
391_V399_I0.6720.37
52_I75_S0.6710.37
325_P563_G0.6690.37
335_L510_F0.6690.37
67_E89_N0.6690.37
424_Y465_V0.6690.37
200_Q520_H0.6670.37
472_K480_N0.6660.37
405_S516_Q0.6640.36
441_P470_F0.6640.36
355_Q363_V0.6640.36
34_E281_R0.6640.36
128_T137_K0.6630.36
197_M522_V0.6630.36
66_R152_A0.6620.36
521_M564_F0.6610.36
615_P631_S0.6610.36
27_R31_E0.6600.36
184_E258_N0.6600.36
336_I418_P0.6590.36
28_R34_E0.6590.36
156_N481_E0.6590.36
90_E99_R0.6580.36
91_V106_I0.6580.36
561_L570_L0.6570.36
373_D569_L0.6570.36
274_M433_I0.6560.36
142_D623_K0.6560.36
53_G624_L0.6560.36
77_E109_N0.6540.36
556_M565_G0.6540.36
337_G370_G0.6530.36
197_M200_Q0.6530.36
211_L214_D0.6510.35
110_G123_E0.6510.35
444_M527_H0.6510.35
383_G506_S0.6500.35
305_V353_P0.6500.35
263_I415_M0.6490.35
23_E31_E0.6490.35
561_L569_L0.6480.35
36_Q638_L0.6480.35
67_E101_R0.6480.35
30_T38_E0.6480.35
64_K67_E0.6470.35
110_G118_D0.6450.35
453_I465_V0.6430.35
131_D629_L0.6410.35
184_E497_D0.6400.35
82_H89_N0.6400.35
144_E249_L0.6400.35
298_I336_I0.6380.34
48_N51_L0.6370.34
522_V527_H0.6370.34
63_N177_A0.6370.34
452_G456_K0.6360.34
623_K638_L0.6360.34
303_A322_V0.6360.34
194_Q203_G0.6360.34
450_M479_Q0.6360.34
540_Q544_G0.6350.34
541_P578_S0.6350.34
30_T33_G0.6350.34
187_Q247_A0.6350.34
132_L135_Q0.6340.34
267_R508_I0.6330.34
137_K431_P0.6330.34
151_V219_L0.6330.34
225_R404_A0.6320.34
29_V382_E0.6310.34
104_L188_S0.6310.34
105_I109_N0.6300.34
439_A452_G0.6300.34
362_I389_V0.6300.34
537_L637_R0.6290.34
158_L415_M0.6290.34
388_K627_Q0.6290.34
186_N407_H0.6280.34
565_G579_D0.6280.34
77_E106_I0.6260.33
119_I123_E0.6260.33
350_E355_Q0.6250.33
293_G360_T0.6250.33
426_V494_V0.6250.33
188_S521_M0.6250.33
262_S458_A0.6230.33
269_S272_R0.6230.33
229_Q472_K0.6220.33
435_L440_L0.6210.33
397_P403_F0.6210.33
28_R38_E0.6210.33
508_I530_A0.6210.33
36_Q592_I0.6200.33
54_Y101_R0.6190.33
173_L264_I0.6180.33
364_T526_L0.6180.33
214_D447_G0.6180.33
154_E158_L0.6180.33
259_M275_Y0.6180.33
46_I99_R0.6170.33
323_V389_V0.6170.33
420_V434_I0.6160.33
45_V48_N0.6150.33
150_Y263_I0.6150.33
334_V363_V0.6150.33
137_K164_H0.6140.33
449_I474_P0.6140.33
64_K73_E0.6110.32
31_E36_Q0.6110.32
53_G97_S0.6110.32
391_V553_F0.6090.32
75_S91_V0.6090.32
31_E272_R0.6080.32
489_P507_R0.6080.32
311_K355_Q0.6070.32
391_V404_A0.6060.32
289_K319_D0.6050.32
338_K517_K0.6050.32
131_D134_R0.6040.32
462_G496_Y0.6040.32
612_N637_R0.6040.32
270_V329_V0.6030.32
634_I640_L0.6030.32
249_L514_Y0.6030.32
76_D79_N0.6010.32
119_I222_Y0.6010.32
348_F354_E0.6010.32
254_F567_A0.6000.32
60_E71_K0.6000.32
362_I365_R0.5980.31
358_R363_V0.5980.31
325_P374_L0.5980.31
393_D535_Q0.5980.31
186_N301_P0.5980.31
44_K446_L0.5970.31
337_G359_D0.5970.31
395_R519_H0.5960.31
291_P358_R0.5950.31
253_S513_V0.5940.31
258_N436_N0.5920.31
229_Q232_A0.5910.31
91_V99_R0.5910.31
279_F337_G0.5900.31
436_N470_F0.5900.31
67_E74_I0.5900.31
187_Q197_M0.5890.31
406_R527_H0.5890.31
397_P515_Y0.5880.31
90_E337_G0.5880.31
39_Y347_E0.5880.31
99_R108_S0.5880.31
201_A245_N0.5870.31
258_N441_P0.5870.31
522_V552_R0.5870.31
198_A533_P0.5860.30
70_R527_H0.5860.30
229_Q464_I0.5850.30
179_I391_V0.5850.30
316_L473_T0.5850.30
55_Y61_L0.5840.30
549_G552_R0.5840.30
404_A407_H0.5840.30
225_R229_Q0.5840.30
104_L141_L0.5810.30
228_V514_Y0.5810.30
346_Q349_K0.5800.30
196_A435_L0.5800.30
371_I394_L0.5790.30
349_K355_Q0.5780.30
145_E515_Y0.5770.30
191_N197_M0.5770.30
182_Y362_I0.5770.30
553_F561_L0.5760.30
283_Y582_M0.5750.30
476_E481_E0.5750.30
298_I335_L0.5750.30
120_E123_E0.5740.30
251_V440_L0.5710.29
332_G360_T0.5700.29
80_V86_D0.5700.29
189_P259_M0.5690.29
217_A390_R0.5690.29
167_I372_V0.5690.29
262_S395_R0.5690.29
254_F506_S0.5680.29
179_I487_Y0.5660.29
265_M516_Q0.5660.29
623_K629_L0.5650.29
60_E78_V0.5650.29
120_E125_G0.5640.29
80_V164_H0.5640.29
479_Q486_G0.5630.29
264_I387_V0.5630.29
101_R106_I0.5630.29
537_L620_Y0.5620.29
138_I225_R0.5620.29
182_Y413_I0.5610.29
266_N397_P0.5610.29
450_M455_G0.5580.28
193_Y198_A0.5580.28
397_P456_K0.5580.28
101_R458_A0.5570.28
225_R464_I0.5560.28
175_I455_G0.5560.28
273_G396_I0.5560.28
262_S393_D0.5550.28
116_I122_L0.5540.28
59_G71_K0.5540.28
175_I449_I0.5520.28
377_I508_I0.5520.28
31_E434_I0.5510.28
253_S258_N0.5500.28
83_I92_H0.5500.28
73_E91_V0.5480.28
56_Q64_K0.5470.28
84_V182_Y0.5450.28
527_H546_A0.5450.28
116_I124_S0.5440.28
268_S416_L0.5440.28
197_M527_H0.5430.27
144_E384_N0.5420.27
122_L387_V0.5410.27
533_P548_E0.5410.27
75_S78_V0.5410.27
172_I633_I0.5400.27
111_N389_V0.5400.27
368_E623_K0.5400.27
620_Y623_K0.5390.27
453_I479_Q0.5390.27
508_I514_Y0.5380.27
457_Y500_T0.5380.27
101_R619_S0.5380.27
112_P449_I0.5370.27
531_R548_E0.5370.27
63_N89_N0.5370.27
333_D567_A0.5360.27
56_Q63_N0.5360.27
416_L572_D0.5360.27
37_N346_Q0.5360.27
485_Y488_L0.5350.27
66_R107_V0.5350.27
122_L610_K0.5330.27
467_A472_K0.5330.27
237_G610_K0.5320.27
572_D591_Y0.5320.27
104_L108_S0.5310.27
539_R551_L0.5310.27
140_Y263_I0.5300.27
136_G626_I0.5300.27
207_A241_R0.5290.26
541_P549_G0.5280.26
91_V450_M0.5280.26
33_G37_N0.5280.26
268_S420_V0.5280.26
329_V570_L0.5270.26
26_I29_V0.5270.26
332_G459_A0.5260.26
300_M381_A0.5260.26
100_V180_I0.5260.26
62_A75_S0.5250.26
557_E578_S0.5250.26
181_P408_G0.5240.26
479_Q489_P0.5240.26
251_V517_K0.5230.26
393_D432_D0.5230.26
482_I573_R0.5230.26
453_I475_I0.5230.26
492_T506_S0.5220.26
177_A422_M0.5210.26
191_N203_G0.5200.26
230_T493_E0.5190.26
54_Y92_H0.5190.26
139_E375_V0.5190.26
456_K482_I0.5180.26
372_V530_A0.5180.26
71_K375_V0.5180.26
433_I461_S0.5180.26
352_S355_Q0.5170.26
555_E565_G0.5160.26
110_G116_I0.5160.26
231_R504_I0.5150.26
358_R382_E0.5150.26
352_S356_A0.5140.25
533_P572_D0.5140.25
478_L482_I0.5140.25
187_Q445_T0.5140.25
129_F515_Y0.5140.25
182_Y472_K0.5140.25
281_R365_R0.5130.25
150_Y161_D0.5130.25
30_T35_D0.5120.25
474_P490_D0.5120.25
119_I424_Y0.5110.25
117_E140_Y0.5110.25
36_Q39_Y0.5110.25
391_V634_I0.5100.25
241_R326_E0.5100.25
54_Y106_I0.5100.25
393_D519_H0.5100.25
128_T304_G0.5100.25
345_L349_K0.5100.25
508_I521_M0.5100.25
393_D397_P0.5100.25
258_N440_L0.5090.25
374_L390_R0.5090.25
266_N269_S0.5090.25
250_A515_Y0.5090.25
292_G546_A0.5080.25
29_V320_N0.5080.25
166_E469_P0.5080.25
63_N66_R0.5080.25
509_Y521_M0.5080.25
75_S89_N0.5070.25
27_R36_Q0.5070.25
195_S344_F0.5070.25
200_Q555_E0.5050.25
556_M579_D0.5050.25
117_E125_G0.5050.25
439_A520_H0.5040.25
567_A613_L0.5040.25
488_L493_E0.5040.25
171_A182_Y0.5030.25
264_I298_I0.5030.25
185_H567_A0.5030.25
479_Q524_D0.5030.25
437_P470_F0.5030.25
537_L543_E0.5020.25
618_V629_L0.5020.25
120_E128_T0.5010.25
395_R547_R0.5010.25
251_V405_S0.5010.25
182_Y447_G0.5010.25
594_W607_H0.5000.25
34_E41_K0.5000.25
32_G41_K0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3h0gB 1 0.9723 100 0.069 Contact Map
1twfB 2 0.9476 100 0.069 Contact Map
4qiwB 1 0.9322 100 0.077 Contact Map
4aybB 1 0.9753 100 0.078 Contact Map
2a6hC 1 0.9646 100 0.136 Contact Map
4yfkC 1 0.9522 100 0.149 Contact Map
4c2mB 1 0.9214 100 0.169 Contact Map
2ly7A 1 0.1911 100 0.876 Contact Map
3woeA 1 0.1757 99.8 0.911 Contact Map
3tbiB 1 0.2111 99.8 0.917 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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