IF2P - SULSO - GREMLIN Contacts

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IF2P - Probable translation initiation factor IF-2

UniProt:	Q980Q8	Sequences: MKISNSERRLRQPIVVVLGHVDHGKTTLLDKIRGTTVVKKEPGEMTQEVGASFVPSYIIEKLAEPLKKVIPIKLQIPGLLFIDTPGHEYFSNLRRRGGSVADIAILVVDITEGLQKQSIESIQILRERKVPFLIAANKIDKIPGWKSNNDIPFLASIEKQRNDVKVYLDNLVYNLVSQLANLGFSSERYDRIKDFTKTVAIVPVSAKTGEGVADLLALLAGLTQRYLETRLKFAEGPAKGVILEVKEDPGLGHTIDVIIYDGVLKKNDTIILGGINGIIITKVRGIFVPRPLQDMKLSKYDLTPIDEVYAAAGVKISAPNLEEALAGSPIYVVEDESKVERYKQQIEEEIKEVRLYSDIDGIILKADSLGTLEALVSALQREGIPIRLADIGPISKRDVIEASIVAQRSKEYGIIAAFRVKLLQGIDTSGIKILYNEIIYQLIEDIKKHINDVREAEKRRTFDTLILPGKIKILPGYVFRRSDPVVVGIEVIGGIIRPKYPLIKEDGRRVGEVLQIQDNKKSLERATKGMEVAISIKGNIMIGRHVNEGDVLYTDVPKEDLEILVNKYPSSITDDMREVIKEIIRIKRKEDPLYGLGLQI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	600 (454)
Sequences:	6136 (2888)
Seq/√Len:	135.5

ECOLI - IF2 EFG TYPA
BACSU - IF2 EFG TYPA
HALSA - IF2P
SULSO - IF2P

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
294_D	300_Y	5.085	1.00
105_I	219_L	3.966	1.00
119_I	182_L	3.462	1.00
239_K	261_D	3.435	1.00
284_R	289_P	3.398	1.00
265_K	293_Q	3.393	1.00
211_G	214_D	3.074	1.00
31_K	209_G	3.014	1.00
111_T	141_K	2.991	1.00
204_V	215_L	2.950	1.00
77_P	225_R	2.780	1.00
200_A	218_L	2.678	1.00
447_K	451_N	2.660	1.00
409_S	414_I	2.631	1.00
268_D	317_S	2.582	1.00
366_A	372_L	2.580	1.00
145_W	148_N	2.526	1.00
501_P	512_E	2.512	1.00
31_K	212_V	2.352	1.00
232_K	235_E	2.334	1.00
313_G	316_I	2.297	1.00
223_T	227_L	2.283	1.00
409_S	415_I	2.210	1.00
399_V	402_A	2.195	1.00
394_I	413_G	2.178	1.00
263_V	293_Q	2.176	1.00
218_L	225_R	2.174	1.00
476_G	485_V	2.110	1.00
375_L	442_L	2.096	1.00
474_L	490_E	2.091	1.00
202_V	218_L	2.082	1.00
139_I	210_E	2.055	1.00
312_A	315_K	2.016	1.00
232_K	236_G	1.996	1.00
468_P	500_Y	1.981	1.00
414_I	417_A	1.979	1.00
336_E	340_E	1.944	1.00
441_Q	444_E	1.934	1.00
135_A	204_V	1.925	1.00
125_L	132_F	1.925	1.00
34_G	209_G	1.915	1.00
327_G	331_Y	1.915	1.00
176_V	194_D	1.896	1.00
275_I	307_E	1.888	1.00
39_K	51_A	1.875	1.00
236_G	261_D	1.870	1.00
410_K	414_I	1.841	1.00
399_V	411_E	1.831	1.00
409_S	416_A	1.817	1.00
482_S	485_V	1.805	1.00
409_S	412_Y	1.794	1.00
353_V	356_Y	1.791	1.00
136_A	203_P	1.786	1.00
100_V	241_V	1.776	1.00
409_S	419_R	1.767	1.00
411_E	415_I	1.765	1.00
266_K	292_L	1.737	1.00
399_V	406_A	1.736	1.00
32_I	212_V	1.732	1.00
329_P	332_V	1.723	1.00
414_I	419_R	1.706	1.00
482_S	486_V	1.701	1.00
355_L	358_D	1.692	1.00
176_V	203_P	1.691	1.00
416_A	424_Q	1.685	1.00
137_N	206_A	1.683	1.00
409_S	417_A	1.667	1.00
346_I	349_E	1.655	1.00
347_E	350_I	1.655	1.00
246_K	256_D	1.638	1.00
123_Q	388_L	1.632	1.00
351_K	358_D	1.612	1.00
48_E	368_S	1.607	1.00
119_I	123_Q	1.605	1.00
286_I	289_P	1.600	1.00
110_I	144_G	1.600	1.00
483_D	486_V	1.598	1.00
291_P	294_D	1.574	1.00
350_I	353_V	1.574	1.00
291_P	296_K	1.569	1.00
285_G	289_P	1.561	1.00
419_R	424_Q	1.551	1.00
284_R	287_F	1.544	1.00
412_Y	415_I	1.523	1.00
320_N	323_E	1.522	1.00
470_K	493_G	1.515	1.00
106_L	134_I	1.513	1.00
54_V	72_I	1.506	1.00
76_I	217_A	1.506	1.00
351_K	355_L	1.504	1.00
417_A	420_V	1.491	1.00
295_M	298_S	1.491	1.00
410_K	419_R	1.485	1.00
353_V	358_D	1.474	1.00
178_Q	181_N	1.474	1.00
352_E	358_D	1.469	1.00
136_A	201_I	1.462	1.00
16_V	104_A	1.459	1.00
444_E	447_K	1.455	1.00
40_K	43_G	1.445	1.00
328_S	332_V	1.441	1.00
514_L	517_Q	1.441	1.00
426_I	433_I	1.439	1.00
398_D	406_A	1.436	1.00
291_P	300_Y	1.434	1.00
399_V	405_V	1.420	1.00
10_L	77_P	1.415	1.00
312_A	316_I	1.406	1.00
180_A	185_S	1.403	1.00
402_A	406_A	1.393	1.00
410_K	415_I	1.389	1.00
436_N	445_D	1.381	1.00
473_I	485_V	1.380	1.00
416_A	419_R	1.379	1.00
420_V	424_Q	1.379	1.00
146_K	203_P	1.370	1.00
126_R	183_G	1.368	1.00
415_I	419_R	1.358	1.00
109_D	112_E	1.358	1.00
180_A	195_F	1.355	1.00
414_I	418_F	1.348	1.00
352_E	355_L	1.343	1.00
315_K	318_A	1.342	1.00
345_Q	350_I	1.338	1.00
31_K	34_G	1.334	1.00
294_D	298_S	1.328	1.00
113_G	178_Q	1.323	1.00
192_I	201_I	1.320	1.00
513_V	517_Q	1.318	1.00
412_Y	419_R	1.317	1.00
234_A	263_V	1.311	1.00
29_L	81_F	1.309	1.00
419_R	422_L	1.306	1.00
345_Q	348_E	1.305	1.00
410_K	417_A	1.304	1.00
193_K	200_A	1.296	1.00
271_I	278_I	1.292	1.00
53_F	80_L	1.289	1.00
217_A	224_Q	1.289	1.00
352_E	356_Y	1.282	1.00
398_D	402_A	1.280	1.00
334_E	338_K	1.275	1.00
328_S	331_Y	1.274	1.00
335_D	339_V	1.268	1.00
257_V	315_K	1.266	1.00
185_S	192_I	1.263	1.00
132_F	184_F	1.263	1.00
338_K	341_R	1.261	1.00
413_G	435_Y	1.260	1.00
432_K	461_T	1.260	1.00
398_D	404_I	1.259	1.00
203_P	210_E	1.251	1.00
397_R	402_A	1.247	1.00
317_S	321_L	1.244	1.00
409_S	424_Q	1.244	1.00
472_K	477_Y	1.239	1.00
348_E	351_K	1.234	1.00
306_D	310_A	1.227	1.00
71_P	78_G	1.224	1.00
73_K	78_G	1.223	1.00
353_V	360_D	1.223	1.00
133_L	219_L	1.221	1.00
313_G	321_L	1.218	1.00
403_S	429_S	1.214	1.00
35_T	213_A	1.214	1.00
73_K	76_I	1.213	1.00
481_R	486_V	1.209	1.00
346_I	350_I	1.206	1.00
53_F	78_G	1.206	1.00
491_V	496_I	1.205	1.00
421_K	424_Q	1.200	1.00
283_V	289_P	1.196	1.00
28_L	212_V	1.193	1.00
192_I	195_F	1.189	1.00
74_L	77_P	1.188	0.99
356_Y	359_I	1.182	0.99
377_S	381_R	1.181	0.99
397_R	406_A	1.180	0.99
417_A	424_Q	1.178	0.99
414_I	420_V	1.175	0.99
416_A	422_L	1.160	0.99
104_A	130_V	1.156	0.99
504_K	509_R	1.144	0.99
469_G	472_K	1.143	0.99
473_I	477_Y	1.139	0.99
410_K	416_A	1.133	0.99
479_F	482_S	1.132	0.99
9_R	234_A	1.131	0.99
345_Q	349_E	1.123	0.99
313_G	322_E	1.123	0.99
413_G	416_A	1.116	0.99
351_K	360_D	1.116	0.99
184_F	199_V	1.114	0.99
105_I	135_A	1.113	0.99
329_P	333_V	1.113	0.99
348_E	352_E	1.106	0.99
468_P	473_I	1.106	0.99
351_K	356_Y	1.105	0.99
350_I	355_L	1.102	0.99
398_D	405_V	1.094	0.99
415_I	420_V	1.091	0.99
502_L	513_V	1.091	0.99
283_V	290_R	1.091	0.99
314_V	317_S	1.089	0.99
238_A	264_L	1.088	0.99
377_S	380_Q	1.087	0.99
409_S	423_L	1.086	0.99
335_D	338_K	1.085	0.99
398_D	401_E	1.083	0.99
413_G	417_A	1.082	0.99
409_S	418_F	1.079	0.99
356_Y	360_D	1.077	0.99
473_I	476_G	1.075	0.99
355_L	360_D	1.074	0.99
145_W	177_S	1.072	0.99
327_G	330_I	1.071	0.99
409_S	413_G	1.071	0.99
294_D	301_D	1.068	0.99
283_V	286_I	1.068	0.99
328_S	333_V	1.065	0.99
108_V	118_S	1.061	0.99
246_K	301_D	1.060	0.99
330_I	333_V	1.056	0.99
114_L	201_I	1.056	0.99
313_G	317_S	1.055	0.99
350_I	358_D	1.054	0.99
332_V	335_D	1.053	0.99
303_T	310_A	1.051	0.99
504_K	507_G	1.050	0.99
419_R	425_G	1.049	0.99
481_R	485_V	1.048	0.99
347_E	351_K	1.044	0.99
412_Y	425_G	1.041	0.99
506_D	509_R	1.040	0.99
209_G	212_V	1.040	0.99
282_K	289_P	1.039	0.99
139_I	146_K	1.038	0.99
291_P	298_S	1.038	0.99
35_T	212_V	1.037	0.99
376_V	389_A	1.031	0.99
352_E	359_I	1.024	0.98
512_E	515_Q	1.021	0.98
32_I	216_L	1.020	0.98
349_E	353_V	1.020	0.98
420_V	423_L	1.018	0.98
414_I	425_G	1.016	0.98
15_V	79_L	1.016	0.98
393_P	507_G	1.014	0.98
232_K	261_D	1.013	0.98
147_S	203_P	1.011	0.98
294_D	299_K	1.009	0.98
316_I	322_E	1.009	0.98
312_A	321_L	1.009	0.98
376_V	380_Q	1.009	0.98
352_E	360_D	1.007	0.98
468_P	472_K	1.006	0.98
208_T	212_V	0.998	0.98
410_K	424_Q	0.998	0.98
8_R	11_R	0.994	0.98
474_L	477_Y	0.991	0.98
468_P	475_P	0.991	0.98
411_E	414_I	0.990	0.98
412_Y	417_A	0.983	0.98
402_A	405_V	0.983	0.98
469_G	473_I	0.977	0.98
471_I	489_I	0.975	0.98
450_I	454_R	0.974	0.98
204_V	211_G	0.974	0.98
347_E	353_V	0.973	0.98
414_I	424_Q	0.972	0.98
413_G	418_F	0.962	0.98
317_S	325_L	0.961	0.98
441_Q	448_K	0.960	0.98
88_E	381_R	0.956	0.98
121_S	124_I	0.953	0.98
414_I	421_K	0.952	0.98
412_Y	416_A	0.951	0.98
488_G	491_V	0.947	0.97
414_I	422_L	0.944	0.97
445_D	449_H	0.942	0.97
500_Y	504_K	0.932	0.97
411_E	417_A	0.927	0.97
119_I	122_I	0.922	0.97
416_A	420_V	0.921	0.97
380_Q	385_P	0.921	0.97
110_I	136_A	0.915	0.97
318_A	321_L	0.914	0.97
493_G	499_K	0.913	0.97
47_Q	50_G	0.913	0.97
135_A	206_A	0.912	0.97
315_K	322_E	0.911	0.97
414_I	423_L	0.907	0.97
412_Y	420_V	0.907	0.97
437_E	441_Q	0.906	0.97
234_A	295_M	0.904	0.97
497_R	500_Y	0.901	0.97
270_I	305_I	0.898	0.97
317_S	322_E	0.897	0.97
251_L	283_V	0.897	0.97
253_H	308_V	0.896	0.97
424_Q	428_T	0.895	0.96
469_G	474_L	0.893	0.96
417_A	422_L	0.892	0.96
425_G	429_S	0.890	0.96
31_K	208_T	0.889	0.96
355_L	359_I	0.889	0.96
79_L	219_L	0.889	0.96
9_R	235_E	0.887	0.96
74_L	217_A	0.887	0.96
269_T	278_I	0.886	0.96
78_G	298_S	0.886	0.96
294_D	297_L	0.884	0.96
231_L	234_A	0.878	0.96
198_T	201_I	0.878	0.96
12_Q	298_S	0.877	0.96
424_Q	427_D	0.877	0.96
512_E	517_Q	0.875	0.96
211_G	215_L	0.872	0.96
401_E	406_A	0.870	0.96
409_S	425_G	0.869	0.96
415_I	418_F	0.869	0.96
315_K	321_L	0.865	0.96
468_P	477_Y	0.863	0.96
37_V	40_K	0.860	0.96
409_S	422_L	0.859	0.96
53_F	298_S	0.857	0.95
342_Y	346_I	0.855	0.95
347_E	352_E	0.855	0.95
397_R	405_V	0.850	0.95
283_V	301_D	0.850	0.95
282_K	287_F	0.848	0.95
346_I	351_K	0.848	0.95
423_L	427_D	0.839	0.95
200_A	223_T	0.830	0.95
419_R	423_L	0.827	0.95
243_L	256_D	0.826	0.95
253_H	348_E	0.825	0.94
472_K	475_P	0.824	0.94
349_E	355_L	0.824	0.94
34_G	41_E	0.823	0.94
12_Q	78_G	0.821	0.94
18_L	106_L	0.821	0.94
27_T	207_K	0.821	0.94
401_E	405_V	0.820	0.94
92_N	377_S	0.820	0.94
43_G	46_T	0.819	0.94
342_Y	350_I	0.818	0.94
291_P	295_M	0.815	0.94
54_V	73_K	0.814	0.94
327_G	333_V	0.813	0.94
473_I	479_F	0.812	0.94
400_I	403_S	0.809	0.94
468_P	479_F	0.809	0.94
353_V	359_I	0.807	0.94
468_P	471_I	0.806	0.94
282_K	285_G	0.806	0.94
397_R	401_E	0.804	0.94
410_K	413_G	0.804	0.94
282_K	286_I	0.804	0.94
511_G	517_Q	0.801	0.94
204_V	208_T	0.797	0.93
399_V	404_I	0.795	0.93
108_V	134_I	0.793	0.93
351_K	354_R	0.792	0.93
346_I	352_E	0.792	0.93
224_Q	227_L	0.790	0.93
109_D	141_K	0.789	0.93
124_I	128_R	0.789	0.93
272_L	315_K	0.785	0.93
207_K	210_E	0.785	0.93
305_I	308_V	0.783	0.93
239_K	260_Y	0.781	0.93
16_V	130_V	0.781	0.93
410_K	421_K	0.780	0.93
349_E	352_E	0.780	0.93
265_K	268_D	0.780	0.93
409_S	420_V	0.779	0.93
312_A	322_E	0.777	0.93
273_G	322_E	0.775	0.92
259_I	300_Y	0.772	0.92
468_P	495_I	0.772	0.92
411_E	424_Q	0.771	0.92
475_P	519_N	0.770	0.92
32_I	72_I	0.770	0.92
259_I	294_D	0.768	0.92
378_A	443_I	0.768	0.92
314_V	322_E	0.766	0.92
412_Y	418_F	0.766	0.92
36_T	39_K	0.764	0.92
416_A	425_G	0.764	0.92
344_Q	347_E	0.763	0.92
177_S	181_N	0.762	0.92
316_I	321_L	0.762	0.92
413_G	425_G	0.761	0.92
38_V	72_I	0.760	0.92
42_P	45_M	0.760	0.92
505_E	509_R	0.758	0.92
8_R	232_K	0.756	0.91
420_V	425_G	0.755	0.91
314_V	321_L	0.753	0.91
33_R	38_V	0.753	0.91
471_I	496_I	0.752	0.91
317_S	320_N	0.751	0.91
477_Y	480_R	0.743	0.91
17_V	29_L	0.743	0.91
14_I	258_I	0.742	0.91
263_V	295_M	0.741	0.91
418_F	425_G	0.741	0.91
296_K	299_K	0.741	0.91
203_P	211_G	0.741	0.91
303_T	306_D	0.740	0.91
281_T	303_T	0.740	0.91
122_I	126_R	0.738	0.90
341_R	344_Q	0.738	0.90
447_K	458_K	0.736	0.90
103_I	133_L	0.735	0.90
247_E	253_H	0.733	0.90
418_F	424_Q	0.732	0.90
506_D	510_V	0.731	0.90
16_V	101_A	0.728	0.90
203_P	214_D	0.728	0.90
399_V	403_S	0.725	0.90
347_E	355_L	0.724	0.90
32_I	79_L	0.724	0.90
422_L	425_G	0.724	0.90
176_V	201_I	0.723	0.90
350_I	360_D	0.719	0.89
139_I	203_P	0.719	0.89
340_E	343_K	0.717	0.89
283_V	287_F	0.717	0.89
237_P	319_P	0.713	0.89
476_G	480_R	0.710	0.89
379_L	384_I	0.710	0.89
45_M	50_G	0.710	0.89
471_I	478_V	0.709	0.89
272_L	275_I	0.709	0.89
350_I	356_Y	0.707	0.89
27_T	31_K	0.707	0.89
344_Q	348_E	0.706	0.88
494_G	499_K	0.703	0.88
44_E	47_Q	0.700	0.88
271_I	318_A	0.699	0.88
231_L	236_G	0.698	0.88
513_V	516_I	0.697	0.88
413_G	420_V	0.696	0.88
411_E	425_G	0.692	0.87
340_E	344_Q	0.690	0.87
418_F	422_L	0.690	0.87
296_K	300_Y	0.688	0.87
314_V	318_A	0.688	0.87
475_P	480_R	0.685	0.87
223_T	226_Y	0.685	0.87
327_G	336_E	0.683	0.87
451_N	458_K	0.682	0.87
513_V	519_N	0.681	0.87
467_L	475_P	0.681	0.87
184_F	192_I	0.681	0.87
77_P	220_A	0.681	0.87
472_K	492_I	0.680	0.87
473_I	480_R	0.679	0.86
354_R	358_D	0.678	0.86
238_A	259_I	0.678	0.86
496_I	513_V	0.677	0.86
513_V	518_D	0.676	0.86
496_I	502_L	0.674	0.86
108_V	114_L	0.674	0.86
282_K	290_R	0.673	0.86
110_I	139_I	0.672	0.86
180_A	192_I	0.671	0.86
336_E	348_E	0.669	0.86
298_S	301_D	0.669	0.86
260_Y	297_L	0.667	0.85
33_R	51_A	0.666	0.85
91_S	124_I	0.666	0.85
412_Y	442_L	0.665	0.85
474_L	478_V	0.665	0.85
478_V	485_V	0.665	0.85
322_E	326_A	0.664	0.85
348_E	355_L	0.662	0.85
339_V	343_K	0.662	0.85
337_S	341_R	0.662	0.85
467_L	476_G	0.660	0.85
471_I	475_P	0.659	0.85
123_Q	126_R	0.658	0.85
48_E	51_A	0.656	0.85
364_L	372_L	0.656	0.85
491_V	499_K	0.656	0.85
136_A	146_K	0.653	0.84
473_I	478_V	0.651	0.84
336_E	341_R	0.651	0.84
336_E	344_Q	0.648	0.84
489_I	513_V	0.648	0.84
469_G	475_P	0.645	0.84
247_E	308_V	0.644	0.83
322_E	325_L	0.643	0.83
335_D	350_I	0.643	0.83
357_S	360_D	0.643	0.83
308_V	311_A	0.641	0.83
344_Q	355_L	0.640	0.83
334_E	337_S	0.640	0.83
176_V	180_A	0.640	0.83
469_G	476_G	0.640	0.83
413_G	423_L	0.639	0.83
269_T	280_I	0.639	0.83
412_Y	421_K	0.639	0.83
272_L	305_I	0.639	0.83
411_E	420_V	0.639	0.83
339_V	350_I	0.639	0.83
177_S	180_A	0.638	0.83
495_I	499_K	0.638	0.83
417_A	423_L	0.638	0.83
26_T	29_L	0.638	0.83
22_D	87_H	0.637	0.83
118_S	134_I	0.636	0.83
410_K	420_V	0.634	0.82
175_L	178_Q	0.633	0.82
285_G	290_R	0.632	0.82
467_L	493_G	0.631	0.82
282_K	294_D	0.631	0.82
475_P	479_F	0.631	0.82
348_E	353_V	0.631	0.82
330_I	334_E	0.630	0.82
469_G	477_Y	0.629	0.82
312_A	317_S	0.629	0.82
336_E	339_V	0.629	0.82
471_I	477_Y	0.626	0.82
255_I	308_V	0.624	0.81
241_V	260_Y	0.624	0.81
194_D	203_P	0.623	0.81
175_L	179_L	0.622	0.81
32_I	105_I	0.621	0.81
468_P	476_G	0.621	0.81
411_E	421_K	0.621	0.81
399_V	433_I	0.620	0.81
453_V	458_K	0.620	0.81
236_G	263_V	0.619	0.81
341_R	345_Q	0.619	0.81
242_I	255_I	0.618	0.81
445_D	448_K	0.618	0.81
313_G	318_A	0.612	0.80
419_R	459_R	0.611	0.80
417_A	425_G	0.610	0.80
318_A	322_E	0.610	0.80
32_I	35_T	0.609	0.80
115_Q	141_K	0.608	0.80
393_P	508_R	0.607	0.80
418_F	435_Y	0.607	0.80
45_M	49_V	0.606	0.80
339_V	346_I	0.604	0.79
492_I	495_I	0.603	0.79
468_P	474_L	0.603	0.79
471_I	474_L	0.603	0.79
472_K	478_V	0.602	0.79
321_L	325_L	0.601	0.79
339_V	348_E	0.601	0.79
183_G	192_I	0.600	0.79
372_L	389_A	0.600	0.79
413_G	424_Q	0.600	0.79
336_E	349_E	0.600	0.79
82_I	92_N	0.597	0.79
480_R	485_V	0.597	0.79
240_G	315_K	0.597	0.79
413_G	422_L	0.596	0.78
95_R	127_E	0.595	0.78
96_R	373_E	0.592	0.78
421_K	425_G	0.591	0.78
235_E	263_V	0.591	0.78
411_E	416_A	0.589	0.78
313_G	319_P	0.589	0.78
482_S	502_L	0.589	0.78
349_E	358_D	0.586	0.77
41_E	47_Q	0.586	0.77
16_V	98_G	0.585	0.77
344_Q	350_I	0.585	0.77
257_V	302_L	0.584	0.77
467_L	474_L	0.583	0.77
492_I	499_K	0.581	0.77
293_Q	298_S	0.580	0.77
200_A	225_R	0.580	0.77
289_P	292_L	0.579	0.76
514_L	518_D	0.578	0.76
126_R	129_K	0.577	0.76
411_E	419_R	0.576	0.76
292_L	296_K	0.575	0.76
323_E	326_A	0.574	0.76
455_E	458_K	0.571	0.75
476_G	479_F	0.571	0.75
361_G	385_P	0.570	0.75
46_T	49_V	0.569	0.75
192_I	199_V	0.568	0.75
409_S	421_K	0.567	0.75
250_G	364_L	0.564	0.75
337_S	340_E	0.563	0.74
140_D	205_S	0.562	0.74
438_I	442_L	0.562	0.74
438_I	441_Q	0.560	0.74
296_K	301_D	0.559	0.74
87_H	96_R	0.559	0.74
306_D	311_A	0.559	0.74
333_V	336_E	0.557	0.74
216_L	220_A	0.555	0.73
342_Y	345_Q	0.555	0.73
42_P	437_E	0.553	0.73
331_Y	387_R	0.553	0.73
363_I	411_E	0.552	0.73
512_E	516_I	0.552	0.73
340_E	345_Q	0.551	0.73
479_F	517_Q	0.551	0.73
349_E	360_D	0.550	0.73
417_A	508_R	0.549	0.73
392_G	440_Y	0.547	0.72
412_Y	424_Q	0.546	0.72
87_H	117_Q	0.546	0.72
340_E	357_S	0.546	0.72
38_V	51_A	0.545	0.72
449_H	452_D	0.545	0.72
122_I	182_L	0.544	0.72
270_I	315_K	0.544	0.72
200_A	226_Y	0.544	0.72
490_E	494_G	0.543	0.72
500_Y	513_V	0.537	0.71
27_T	206_A	0.536	0.71
8_R	230_R	0.536	0.71
444_E	448_K	0.536	0.71
364_L	442_L	0.533	0.70
417_A	421_K	0.533	0.70
331_Y	335_D	0.533	0.70
481_R	494_G	0.532	0.70
396_K	406_A	0.532	0.70
343_K	349_E	0.532	0.70
475_P	478_V	0.530	0.70
343_K	347_E	0.529	0.70
346_I	354_R	0.529	0.70
341_R	348_E	0.528	0.70
348_E	358_D	0.528	0.70
52_S	80_L	0.528	0.70
291_P	299_K	0.528	0.70
470_K	492_I	0.527	0.70
495_I	501_P	0.527	0.70
410_K	422_L	0.527	0.70
331_Y	334_E	0.526	0.69
413_G	419_R	0.525	0.69
346_I	358_D	0.524	0.69
467_L	504_K	0.524	0.69
467_L	470_K	0.524	0.69
316_I	325_L	0.524	0.69
182_L	192_I	0.524	0.69
504_K	508_R	0.524	0.69
472_K	479_F	0.522	0.69
414_I	433_I	0.522	0.69
107_V	204_V	0.522	0.69
346_I	353_V	0.518	0.68
516_I	519_N	0.518	0.68
338_K	342_Y	0.516	0.68
450_I	453_V	0.514	0.68
41_E	44_E	0.513	0.67
17_V	133_L	0.513	0.67
314_V	319_P	0.512	0.67
263_V	296_K	0.511	0.67
212_V	216_L	0.511	0.67
210_E	214_D	0.510	0.67
474_L	480_R	0.510	0.67
339_V	344_Q	0.509	0.67
415_I	424_Q	0.507	0.67
270_I	279_I	0.507	0.67
269_T	318_A	0.506	0.66
240_G	258_I	0.505	0.66
45_M	48_E	0.505	0.66
111_T	148_N	0.505	0.66
271_I	276_N	0.505	0.66
307_E	310_A	0.505	0.66
291_P	301_D	0.505	0.66
202_V	215_L	0.504	0.66
342_Y	349_E	0.503	0.66
310_A	313_G	0.503	0.66
264_L	281_T	0.503	0.66
480_R	517_Q	0.502	0.66
503_I	509_R	0.502	0.66
285_G	291_P	0.500	0.66
102_D	258_I	0.500	0.66
318_A	323_E	0.500	0.66

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1g7sA	1	0.9267	100	0.343	Contact Map
4upyB	1	0.9417	100	0.389	Contact Map
3wbiA	1	0.92	100	0.397	Contact Map
4n3nA	2	0.9333	100	0.404	Contact Map
3izyP	1	0.8067	100	0.416	Contact Map
1zo1I	1	0.8167	100	0.421	Contact Map
3j4jA	1	0.825	100	0.435	Contact Map
1darA	1	0.8033	100	0.526	Contact Map
4kiyV	1	0.8933	100	0.53	Contact Map
3j25A	1	0.915	100	0.531	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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