Q980P8 - SULSO - GREMLIN Contacts

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Q980P8 - Adenylosuccinate lyase

UniProt:	Q980P8	Sequences: MRLQYKLINVEHTLQLAMEDSICPLEWRYGSNEMRKFFSREEILKRRIQVEIALLKALTKYGLVKEEDVQKVEKASLTIRPEEVDELESKIGHDVMAMVVLMAERSGDSGRYVHFGATSYDIVDTAYALVFRDAIRLVKTKVVEILEMMVSLAIKYKDLAMVGRTHGQHALPITLGFKIANYIYEFSRSLERLNEVEKRIVKGKMAGAVGTMAAWGNIGLEIEENVMKFLGLRPHEISTQVAPRDAFAELTSDLAILASQCDRFALEVRELMRPEINEISEGVEGRVGSSTMPQKENPVTSEKIGGLAKVLRSLVVASLENIPLWHERDLTNSSSERIIISHEFLVIDEILDSMISLLRNLRVNFENIEKNLNLTKGQIMAESLMINLTLKGMKRHEAHQYVNKLTSKVRQTGKTLLEVCLEDSLILSYFSKQELENVLNPKNYLGSYDKLIERAISYAKGVIKGSEIREAQDR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	474 (412)
Sequences:	11042 (5662)
Seq/√Len:	279.0

ECOLI - ARLY PUR8 ASPA FUMC
BACSU - PUR8 ARLY FUMC ASPA
HALSA - ARLY Q9HS42 FUMC
SULSO - Q980P8 ARLY FUMC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
59_T	69_V	3.916	1.00
68_D	112_Y	3.546	1.00
52_I	77_L	3.412	1.00
367_N	370_K	3.281	1.00
56_K	73_E	3.246	1.00
136_R	197_E	3.134	1.00
408_K	412_T	3.104	1.00
431_S	434_E	2.872	1.00
46_R	133_D	2.822	1.00
143_V	190_L	2.806	1.00
280_S	362_R	2.766	1.00
258_A	311_L	2.763	1.00
369_E	373_N	2.712	1.00
146_L	187_S	2.700	1.00
148_M	359_R	2.644	1.00
139_K	194_N	2.613	1.00
135_I	250_L	2.612	1.00
175_L	363_V	2.532	1.00
280_S	364_N	2.503	1.00
144_E	355_I	2.477	1.00
199_R	249_E	2.471	1.00
139_K	190_L	2.389	1.00
42_E	345_L	2.355	1.00
310_V	338_I	2.314	1.00
152_L	155_K	2.309	1.00
307_L	349_E	2.309	1.00
255_A	315_V	2.305	1.00
158_D	365_F	2.269	1.00
132_R	201_V	2.267	1.00
59_T	66_E	2.264	1.00
60_K	225_N	2.220	1.00
314_L	343_E	2.201	1.00
65_K	68_D	2.124	1.00
143_V	194_N	2.064	1.00
370_K	374_L	2.062	1.00
225_N	228_K	2.011	1.00
282_G	360_N	2.009	1.00
146_L	190_L	1.995	1.00
367_N	371_N	1.991	1.00
83_E	86_E	1.976	1.00
393_M	401_Y	1.970	1.00
78_T	102_M	1.954	1.00
151_S	359_R	1.937	1.00
259_S	312_R	1.930	1.00
414_K	422_E	1.916	1.00
369_E	442_K	1.911	1.00
151_S	155_K	1.910	1.00
66_E	70_Q	1.902	1.00
190_L	194_N	1.889	1.00
195_E	199_R	1.884	1.00
148_M	358_L	1.884	1.00
417_L	436_E	1.877	1.00
60_K	222_I	1.856	1.00
142_V	257_L	1.846	1.00
265_A	304_I	1.830	1.00
195_E	198_K	1.797	1.00
56_K	229_F	1.793	1.00
192_R	249_E	1.792	1.00
408_K	427_L	1.790	1.00
70_Q	74_K	1.760	1.00
52_I	73_E	1.733	1.00
78_T	105_R	1.717	1.00
49_Q	133_D	1.716	1.00
156_Y	159_L	1.708	1.00
432_K	436_E	1.707	1.00
440_N	443_N	1.691	1.00
189_S	260_Q	1.681	1.00
150_V	187_S	1.681	1.00
224_E	228_K	1.678	1.00
28_R	105_R	1.665	1.00
365_F	369_E	1.650	1.00
261_C	304_I	1.648	1.00
146_L	183_I	1.641	1.00
421_L	432_K	1.635	1.00
221_E	225_N	1.601	1.00
401_Y	404_K	1.589	1.00
69_V	73_E	1.587	1.00
83_E	104_E	1.582	1.00
221_E	224_E	1.570	1.00
414_K	419_V	1.564	1.00
24_P	27_W	1.546	1.00
434_E	437_N	1.543	1.00
148_M	355_I	1.527	1.00
317_A	334_S	1.520	1.00
355_I	359_R	1.506	1.00
153_A	183_I	1.502	1.00
141_K	352_D	1.496	1.00
222_I	226_V	1.479	1.00
205_M	222_I	1.447	1.00
188_R	245_D	1.419	1.00
207_G	240_Q	1.416	1.00
152_L	156_Y	1.407	1.00
28_R	31_S	1.406	1.00
45_K	49_Q	1.400	1.00
71_K	107_G	1.396	1.00
146_L	186_F	1.393	1.00
201_V	230_L	1.377	1.00
196_V	253_D	1.375	1.00
415_T	418_E	1.368	1.00
401_Y	429_Y	1.367	1.00
414_K	418_E	1.363	1.00
319_L	322_I	1.352	1.00
354_M	359_R	1.344	1.00
301_S	357_L	1.337	1.00
57_A	225_N	1.336	1.00
191_E	199_R	1.336	1.00
95_V	99_V	1.331	1.00
141_K	351_L	1.329	1.00
244_R	332_N	1.325	1.00
408_K	419_V	1.321	1.00
227_M	233_R	1.321	1.00
364_N	367_N	1.316	1.00
141_K	348_D	1.311	1.00
252_S	256_I	1.309	1.00
277_N	367_N	1.308	1.00
24_P	31_S	1.304	1.00
134_A	348_D	1.300	1.00
248_A	256_I	1.291	1.00
421_L	436_E	1.290	1.00
366_E	370_K	1.275	1.00
101_L	105_R	1.275	1.00
314_L	342_H	1.275	1.00
179_I	182_Y	1.274	1.00
144_E	359_R	1.268	1.00
48_I	95_V	1.262	1.00
225_N	229_F	1.259	1.00
42_E	134_A	1.252	1.00
52_I	56_K	1.251	1.00
150_V	154_I	1.251	1.00
131_F	250_L	1.250	1.00
47_R	122_I	1.246	1.00
201_V	233_R	1.239	1.00
154_I	157_K	1.234	1.00
148_M	151_S	1.233	1.00
139_K	197_E	1.225	1.00
270_E	325_W	1.216	1.00
145_I	355_I	1.216	1.00
175_L	179_I	1.212	1.00
27_W	31_S	1.209	1.00
28_R	32_N	1.207	1.00
24_P	28_R	1.205	1.00
56_K	225_N	1.205	1.00
250_L	344_F	1.200	1.00
63_L	115_F	1.200	1.00
101_L	104_E	1.197	1.00
142_V	186_F	1.196	1.00
264_F	354_M	1.192	1.00
159_L	365_F	1.187	1.00
24_P	30_G	1.186	1.00
60_K	221_E	1.184	1.00
103_A	110_G	1.183	1.00
156_Y	365_F	1.180	1.00
56_K	226_V	1.177	1.00
52_I	80_R	1.174	1.00
313_S	317_A	1.172	1.00
182_Y	327_E	1.169	1.00
71_K	74_K	1.160	1.00
412_T	419_V	1.153	1.00
48_I	80_R	1.151	1.00
55_L	64_V	1.147	1.00
116_G	215_W	1.145	1.00
257_L	347_I	1.144	1.00
24_P	32_N	1.144	1.00
34_M	37_F	1.142	1.00
203_G	227_M	1.138	1.00
318_S	339_I	1.132	1.00
70_Q	73_E	1.130	1.00
77_L	81_P	1.122	1.00
169_H	275_E	1.116	1.00
175_L	368_I	1.111	1.00
102_M	106_S	1.110	1.00
145_I	186_F	1.109	1.00
279_I	361_L	1.106	1.00
270_E	276_I	1.103	1.00
25_L	28_R	1.096	1.00
157_K	176_G	1.094	1.00
116_G	218_I	1.093	1.00
158_D	176_G	1.087	1.00
149_M	264_F	1.085	1.00
193_L	257_L	1.083	1.00
150_V	183_I	1.078	1.00
251_T	318_S	1.072	1.00
82_E	86_E	1.071	1.00
308_A	312_R	1.068	1.00
191_E	198_K	1.068	1.00
139_K	143_V	1.062	1.00
268_V	301_S	1.061	1.00
304_I	354_M	1.060	1.00
235_H	239_T	1.059	1.00
34_M	38_F	1.054	1.00
143_V	147_E	1.044	1.00
169_H	274_P	1.042	1.00
127_Y	336_E	1.040	1.00
73_E	77_L	1.040	1.00
48_I	79_I	1.034	1.00
141_K	144_E	1.034	1.00
50_V	122_I	1.033	1.00
172_P	372_L	1.029	1.00
262_D	305_G	1.029	1.00
45_K	80_R	1.028	1.00
261_C	350_I	1.028	1.00
144_E	354_M	1.026	1.00
125_T	203_G	1.025	1.00
45_K	133_D	1.022	1.00
36_K	39_S	1.020	1.00
208_A	291_T	1.017	1.00
227_M	232_L	1.013	1.00
182_Y	264_F	1.012	1.00
161_M	368_I	1.011	1.00
71_K	75_A	1.011	1.00
127_Y	247_F	1.010	1.00
392_G	438_V	1.006	1.00
152_L	179_I	1.003	1.00
251_T	343_E	1.003	1.00
49_Q	229_F	1.002	1.00
142_V	190_L	1.002	1.00
53_A	229_F	1.000	1.00
152_L	358_L	0.999	1.00
253_D	257_L	0.999	1.00
277_N	364_N	0.997	1.00
184_Y	188_R	0.997	1.00
145_I	358_L	0.994	1.00
148_M	354_M	0.992	1.00
233_R	240_Q	0.989	1.00
45_K	85_D	0.985	1.00
134_A	137_L	0.983	1.00
33_E	36_K	0.983	1.00
188_R	238_S	0.978	1.00
49_Q	226_V	0.976	1.00
160_A	445_L	0.974	1.00
84_V	102_M	0.973	1.00
77_L	80_R	0.970	1.00
159_L	368_I	0.969	1.00
285_G	356_S	0.969	1.00
174_T	445_L	0.969	1.00
46_R	129_L	0.967	1.00
135_I	197_E	0.966	1.00
393_M	402_V	0.965	1.00
59_T	70_Q	0.964	1.00
157_K	174_T	0.963	1.00
195_E	249_E	0.961	1.00
408_K	411_Q	0.959	1.00
132_R	197_E	0.957	1.00
138_V	347_I	0.956	1.00
23_C	27_W	0.956	1.00
407_S	411_Q	0.956	1.00
63_L	215_W	0.954	1.00
248_A	319_L	0.953	1.00
66_E	69_V	0.949	1.00
197_E	201_V	0.949	1.00
265_A	354_M	0.944	1.00
135_I	193_L	0.943	1.00
41_E	45_K	0.941	1.00
50_V	125_T	0.940	1.00
418_E	422_E	0.935	1.00
47_R	50_V	0.933	1.00
191_E	195_E	0.931	1.00
173_I	209_V	0.928	1.00
405_L	427_L	0.928	1.00
27_W	32_N	0.924	1.00
405_L	419_V	0.922	1.00
410_R	413_G	0.922	1.00
80_R	105_R	0.918	1.00
132_R	136_R	0.918	1.00
92_G	97_A	0.917	1.00
127_Y	340_I	0.915	1.00
252_S	315_V	0.914	1.00
268_V	361_L	0.913	1.00
27_W	30_G	0.907	1.00
392_G	434_E	0.905	1.00
236_E	239_T	0.903	1.00
408_K	422_E	0.900	1.00
65_K	112_Y	0.898	1.00
164_R	169_H	0.891	1.00
166_H	302_E	0.888	1.00
202_K	231_G	0.885	1.00
258_A	347_I	0.884	1.00
163_G	173_I	0.877	1.00
251_T	315_V	0.877	1.00
42_E	133_D	0.874	1.00
254_L	347_I	0.869	1.00
46_R	130_V	0.867	1.00
71_K	109_S	0.867	1.00
144_E	351_L	0.866	1.00
311_L	347_I	0.866	1.00
41_E	85_D	0.866	1.00
57_A	61_Y	0.866	1.00
384_L	420_C	0.862	1.00
201_V	232_L	0.861	1.00
149_M	358_L	0.859	1.00
251_T	339_I	0.853	1.00
78_T	83_E	0.853	1.00
67_E	71_K	0.852	1.00
167_G	270_E	0.852	1.00
417_L	432_K	0.850	1.00
373_N	417_L	0.850	1.00
28_R	84_V	0.849	1.00
409_V	419_V	0.848	1.00
418_E	432_K	0.846	1.00
132_R	232_L	0.845	1.00
178_K	327_E	0.843	1.00
243_P	260_Q	0.842	1.00
270_E	326_H	0.840	1.00
159_L	363_V	0.839	1.00
227_M	230_L	0.837	1.00
146_L	150_V	0.837	1.00
155_K	362_R	0.836	1.00
23_C	31_S	0.835	1.00
75_A	78_T	0.834	1.00
30_G	35_R	0.833	1.00
372_L	441_P	0.830	1.00
131_F	339_I	0.829	1.00
316_V	320_E	0.828	1.00
203_G	223_E	0.828	1.00
408_K	414_K	0.825	1.00
60_K	229_F	0.825	1.00
67_E	70_Q	0.823	1.00
235_H	238_S	0.822	0.99
203_G	224_E	0.820	0.99
149_M	179_I	0.820	0.99
31_S	282_G	0.819	0.99
83_E	87_L	0.819	0.99
147_E	151_S	0.817	0.99
153_A	180_A	0.816	0.99
310_V	342_H	0.814	0.99
337_R	341_S	0.810	0.99
183_I	187_S	0.809	0.99
108_D	111_R	0.804	0.99
149_M	183_I	0.804	0.99
310_V	341_S	0.798	0.99
47_R	95_V	0.795	0.99
100_V	104_E	0.794	0.99
405_L	420_C	0.792	0.99
25_L	30_G	0.791	0.99
435_L	439_L	0.790	0.99
59_T	64_V	0.786	0.99
405_L	416_L	0.786	0.99
160_A	372_L	0.785	0.99
433_Q	437_N	0.784	0.99
74_K	106_S	0.783	0.99
155_K	365_F	0.783	0.99
261_C	354_M	0.783	0.99
158_D	442_K	0.783	0.99
60_K	66_E	0.781	0.99
134_A	344_F	0.780	0.99
188_R	202_K	0.780	0.99
52_I	229_F	0.779	0.99
354_M	358_L	0.778	0.99
56_K	60_K	0.773	0.99
29_Y	32_N	0.773	0.99
92_G	100_V	0.772	0.99
339_I	343_E	0.765	0.99
351_L	355_I	0.764	0.99
131_F	340_I	0.763	0.99
387_N	390_L	0.763	0.99
148_M	152_L	0.762	0.99
180_A	239_T	0.762	0.99
25_L	31_S	0.759	0.99
202_K	246_A	0.757	0.99
23_C	32_N	0.757	0.99
178_K	271_L	0.756	0.99
55_L	69_V	0.754	0.99
156_Y	363_V	0.751	0.99
247_F	340_I	0.747	0.99
201_V	227_M	0.746	0.99
265_A	353_S	0.743	0.99
245_D	260_Q	0.743	0.99
249_E	252_S	0.741	0.99
54_L	117_A	0.740	0.99
310_V	314_L	0.740	0.99
250_L	339_I	0.736	0.99
417_L	421_L	0.734	0.99
141_K	355_I	0.729	0.99
164_R	275_E	0.726	0.99
84_V	87_L	0.725	0.99
27_W	87_L	0.723	0.99
177_F	236_E	0.720	0.99
311_L	346_V	0.719	0.99
56_K	69_V	0.719	0.99
357_L	361_L	0.714	0.99
99_V	113_V	0.713	0.99
57_A	222_I	0.711	0.99
141_K	347_I	0.711	0.99
71_K	106_S	0.710	0.99
161_M	178_K	0.709	0.99
247_F	339_I	0.707	0.98
43_I	123_V	0.707	0.98
102_M	105_R	0.705	0.98
76_S	99_V	0.704	0.98
400_Q	404_K	0.702	0.98
192_R	245_D	0.702	0.98
242_A	327_E	0.701	0.98
363_V	368_I	0.699	0.98
223_E	227_M	0.698	0.98
49_Q	80_R	0.698	0.98
198_K	230_L	0.698	0.98
434_E	438_V	0.697	0.98
23_C	28_R	0.697	0.98
75_A	106_S	0.695	0.98
135_I	196_V	0.694	0.98
317_A	335_S	0.692	0.98
80_R	83_E	0.690	0.98
78_T	84_V	0.689	0.98
259_S	322_I	0.686	0.98
149_M	186_F	0.686	0.98
304_I	349_E	0.684	0.98
128_A	246_A	0.684	0.98
196_V	200_I	0.683	0.98
137_L	141_K	0.682	0.98
143_V	146_L	0.681	0.98
63_L	116_G	0.680	0.98
185_E	260_Q	0.677	0.98
68_D	109_S	0.674	0.98
367_N	374_L	0.671	0.98
147_E	150_V	0.670	0.98
320_E	334_S	0.669	0.98
137_L	348_D	0.669	0.98
55_L	72_V	0.668	0.98
64_V	115_F	0.668	0.98
250_L	254_L	0.668	0.98
156_Y	175_L	0.665	0.98
186_F	189_S	0.665	0.98
223_E	226_V	0.665	0.98
265_A	301_S	0.665	0.98
198_K	201_V	0.664	0.98
76_S	79_I	0.661	0.98
383_S	444_Y	0.660	0.98
181_N	263_R	0.659	0.98
159_L	369_E	0.659	0.98
404_K	408_K	0.659	0.98
202_K	233_R	0.656	0.98
366_E	369_E	0.655	0.98
189_S	256_I	0.655	0.98
159_L	174_T	0.653	0.97
61_Y	221_E	0.652	0.97
257_L	350_I	0.651	0.97
102_M	113_V	0.651	0.97
179_I	368_I	0.650	0.97
81_P	84_V	0.648	0.97
53_A	56_K	0.648	0.97
52_I	69_V	0.648	0.97
142_V	350_I	0.645	0.97
141_K	354_M	0.645	0.97
151_S	154_I	0.644	0.97
414_K	420_C	0.644	0.97
255_A	259_S	0.643	0.97
25_L	32_N	0.643	0.97
202_K	235_H	0.641	0.97
224_E	232_L	0.639	0.97
143_V	187_S	0.638	0.97
271_L	326_H	0.637	0.97
109_S	112_Y	0.637	0.97
338_I	342_H	0.636	0.97
204_K	240_Q	0.635	0.97
108_D	400_Q	0.633	0.97
29_Y	34_M	0.633	0.97
222_I	225_N	0.633	0.97
82_E	105_R	0.633	0.97
55_L	73_E	0.633	0.97
252_S	319_L	0.632	0.97
266_L	305_G	0.632	0.97
310_V	346_V	0.630	0.97
185_E	242_A	0.630	0.97
106_S	109_S	0.627	0.97
430_F	438_V	0.626	0.97
404_K	427_L	0.626	0.97
192_R	195_E	0.624	0.97
393_M	430_F	0.622	0.97
33_E	39_S	0.622	0.97
191_E	194_N	0.621	0.97
415_T	419_V	0.620	0.97
72_V	109_S	0.619	0.97
61_Y	215_W	0.619	0.97
32_N	287_V	0.618	0.96
80_R	84_V	0.618	0.96
419_V	422_E	0.617	0.96
185_E	243_P	0.613	0.96
278_E	371_N	0.613	0.96
150_V	153_A	0.609	0.96
264_F	358_L	0.608	0.96
68_D	71_K	0.608	0.96
248_A	252_S	0.607	0.96
300_T	353_S	0.606	0.96
144_E	148_M	0.605	0.96
316_V	319_L	0.605	0.96
154_I	158_D	0.604	0.96
162_V	372_L	0.602	0.96
55_L	113_V	0.600	0.96
35_R	38_F	0.599	0.96
135_I	139_K	0.599	0.96
153_A	157_K	0.599	0.96
175_L	279_I	0.596	0.96
164_R	276_I	0.595	0.96
138_V	254_L	0.595	0.96
189_S	192_R	0.592	0.96
161_M	173_I	0.592	0.96
174_T	446_G	0.589	0.95
136_R	194_N	0.585	0.95
402_V	406_T	0.584	0.95
387_N	434_E	0.584	0.95
136_R	232_L	0.583	0.95
380_M	444_Y	0.581	0.95
371_N	374_L	0.581	0.95
437_N	443_N	0.580	0.95
372_L	379_I	0.580	0.95
203_G	232_L	0.579	0.95
219_G	222_I	0.577	0.95
338_I	341_S	0.577	0.95
38_F	134_A	0.576	0.95
112_Y	115_F	0.575	0.95
145_I	354_M	0.575	0.95
60_K	219_G	0.575	0.95
23_C	30_G	0.574	0.95
173_I	211_T	0.573	0.95
59_T	73_E	0.572	0.95
52_I	76_S	0.571	0.95
304_I	308_A	0.571	0.95
179_I	361_L	0.569	0.94
380_M	439_L	0.568	0.94
205_M	226_V	0.567	0.94
196_V	250_L	0.566	0.94
285_G	360_N	0.564	0.94
78_T	82_E	0.563	0.94
135_I	200_I	0.561	0.94
312_R	317_A	0.560	0.94
203_G	226_V	0.560	0.94
437_N	440_N	0.560	0.94
145_I	351_L	0.560	0.94
33_E	38_F	0.559	0.94
192_R	199_R	0.558	0.94
307_L	346_V	0.558	0.94
186_F	354_M	0.558	0.94
373_N	415_T	0.557	0.94
442_K	446_G	0.557	0.94
187_S	191_E	0.557	0.94
57_A	221_E	0.556	0.94
430_F	434_E	0.555	0.94
152_L	361_L	0.554	0.94
191_E	202_K	0.553	0.94
182_Y	185_E	0.551	0.93
140_T	144_E	0.550	0.93
82_E	101_L	0.550	0.93
223_E	236_E	0.549	0.93
184_Y	187_S	0.548	0.93
205_M	219_G	0.548	0.93
162_V	379_I	0.547	0.93
274_P	277_N	0.547	0.93
365_F	368_I	0.545	0.93
265_A	305_G	0.545	0.93
48_I	85_D	0.545	0.93
421_L	435_L	0.544	0.93
198_K	202_K	0.544	0.93
64_V	68_D	0.544	0.93
193_L	253_D	0.543	0.93
249_E	256_I	0.543	0.93
405_L	408_K	0.543	0.93
268_V	353_S	0.541	0.93
224_E	227_M	0.540	0.93
196_V	249_E	0.539	0.93
160_A	441_P	0.539	0.93
300_T	357_L	0.537	0.93
74_K	78_T	0.536	0.93
188_R	199_R	0.535	0.92
34_M	328_R	0.534	0.92
304_I	357_L	0.534	0.92
237_I	325_W	0.533	0.92
119_S	204_K	0.532	0.92
378_Q	409_V	0.532	0.92
72_V	102_M	0.532	0.92
139_K	253_D	0.531	0.92
273_R	276_I	0.531	0.92
186_F	257_L	0.530	0.92
49_Q	53_A	0.529	0.92
229_F	232_L	0.529	0.92
107_G	110_G	0.527	0.92
305_G	331_T	0.526	0.92
184_Y	234_P	0.526	0.92
382_E	385_M	0.525	0.92
50_V	126_A	0.525	0.92
88_E	96_M	0.525	0.92
68_D	72_V	0.524	0.92
178_K	267_E	0.524	0.92
314_L	341_S	0.524	0.92
171_L	209_V	0.523	0.92
268_V	358_L	0.522	0.92
262_D	319_L	0.521	0.91
284_E	411_Q	0.521	0.91
169_H	379_I	0.521	0.91
272_M	279_I	0.520	0.91
198_K	233_R	0.518	0.91
312_R	320_E	0.518	0.91
350_I	354_M	0.518	0.91
166_H	330_L	0.517	0.91
200_I	232_L	0.517	0.91
161_M	271_L	0.515	0.91
173_I	177_F	0.514	0.91
79_I	85_D	0.514	0.91
26_E	30_G	0.514	0.91
156_Y	176_G	0.513	0.91
186_F	261_C	0.512	0.91
248_A	321_N	0.512	0.91
23_C	26_E	0.512	0.91
278_E	368_I	0.511	0.91
443_N	446_G	0.511	0.91
385_M	406_T	0.510	0.91
46_R	49_Q	0.509	0.91
188_R	249_E	0.507	0.90
129_L	226_V	0.506	0.90
95_V	126_A	0.506	0.90
349_E	353_S	0.505	0.90
204_K	241_V	0.504	0.90
286_R	299_V	0.503	0.90
311_L	343_E	0.503	0.90
303_K	353_S	0.502	0.90
409_V	414_K	0.502	0.90
173_I	237_I	0.501	0.90
268_V	279_I	0.501	0.90
133_D	136_R	0.500	0.90

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1re5A	4	0.9304	100	0.192	Contact Map
1c3cA	4	0.8924	100	0.203	Contact Map
1q5nA	4	0.8924	100	0.204	Contact Map
2pfmA	4	0.9093	100	0.204	Contact Map
3c8tA	4	0.8882	100	0.211	Contact Map
4eeiA	4	0.884	100	0.211	Contact Map
2e9fA	4	0.9177	100	0.212	Contact Map
1k7wA	4	0.9198	100	0.215	Contact Map
1tj7A	4	0.9304	100	0.216	Contact Map
1dofA	4	0.8122	100	0.232	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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