GREMLIN Database
Q980P0 - HIT-like protein, hypothetical (Hit)
UniProt: Q980P0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 171 (137)
Sequences: 3282 (2255)
Seq/√Len: 192.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
24_C27_C3.8071.00
27_C68_H3.2781.00
24_C68_H3.1701.00
67_R79_E2.9731.00
47_A86_L2.9581.00
46_H82_D2.8611.00
43_R66_Y2.8421.00
77_N88_T2.6481.00
44_G82_D2.5561.00
76_S79_E2.5091.00
87_S123_V2.4301.00
39_Y150_S2.2841.00
75_L121_I2.0741.00
77_N85_T2.0021.00
153_F157_N1.9401.00
81_L85_T1.8071.00
61_V90_A1.7501.00
83_I123_V1.7491.00
67_R76_S1.7301.00
28_R35_D1.7271.00
50_I64_V1.7231.00
34_N40_I1.6331.00
40_I48_F1.6081.00
41_V61_V1.6031.00
42_Y86_L1.5681.00
96_D159_K1.5641.00
144_V149_L1.5551.00
63_V87_S1.5341.00
69_V76_S1.5091.00
73_E95_R1.4961.00
38_N48_F1.4751.00
47_A82_D1.4691.00
58_T148_T1.4531.00
88_T92_R1.4441.00
71_S74_L1.3881.00
29_V38_N1.3831.00
34_N37_Q1.3671.00
80_A84_F1.3581.00
154_K158_T1.3511.00
93_A97_I1.3481.00
151_D155_K1.3461.00
80_A88_T1.3361.00
97_I159_K1.3141.00
95_R103_F1.2861.00
104_N128_R1.2821.00
150_S154_K1.2781.00
48_F66_Y1.2691.00
69_V75_L1.2521.00
40_I43_R1.2401.00
39_Y146_P1.2371.00
63_V125_I1.2121.00
107_V123_V1.2041.00
57_N129_W1.1771.00
26_F117_I1.1681.00
36_E154_K1.1651.00
49_I61_V1.1551.00
84_F123_V1.1541.00
104_N108_N1.1391.00
136_M139_I1.0851.00
83_I121_I1.0621.00
71_S95_R1.0561.00
72_V84_F1.0541.00
145_M148_T1.0521.00
61_V94_I1.0511.00
98_Y152_T1.0511.00
95_R110_G1.0481.00
69_V79_E1.0361.00
94_I156_L1.0241.00
147_E155_K1.0191.00
87_S105_I1.0151.00
112_V130_N0.9971.00
70_P110_G0.9910.99
70_P74_L0.9820.99
49_I90_A0.9800.99
110_G113_A0.9630.99
51_L61_V0.9490.99
49_I86_L0.9440.99
149_L153_F0.9390.99
101_D130_N0.9370.99
104_N113_A0.9070.99
97_I156_L0.8950.99
77_N81_L0.8910.99
70_P118_E0.8820.99
44_G86_L0.8790.99
75_L80_A0.8720.99
151_D154_K0.8710.99
94_I125_I0.8680.99
30_I64_V0.8670.99
39_Y51_L0.8550.98
101_D112_V0.8550.98
148_T151_D0.8540.98
58_T155_K0.8480.98
105_I123_V0.8410.98
82_D86_L0.8410.98
48_F64_V0.8330.98
71_S110_G0.8210.98
69_V121_I0.8160.98
71_S118_E0.8140.98
27_C33_E0.8060.98
91_I95_R0.8020.98
111_R118_E0.7990.98
69_V74_L0.7860.97
39_Y149_L0.7850.97
90_A160_V0.7810.97
46_H79_E0.7660.97
25_L117_I0.7630.97
47_A83_I0.7590.97
128_R132_D0.7590.97
91_I105_I0.7540.97
25_L28_R0.7540.97
49_I63_V0.7490.97
23_E28_R0.7470.96
107_V121_I0.7440.96
144_V152_T0.7410.96
93_A156_L0.7340.96
134_N139_I0.7280.96
102_G112_V0.7150.95
51_L108_N0.7090.95
146_P150_S0.7070.95
100_P129_W0.6980.95
135_F138_V0.6940.95
103_F125_I0.6900.95
115_A118_E0.6890.94
39_Y153_F0.6810.94
72_V105_I0.6800.94
73_E92_R0.6800.94
73_E103_F0.6800.94
29_V50_I0.6770.94
114_G137_P0.6740.94
29_V53_A0.6740.94
57_N126_V0.6700.94
51_L149_L0.6690.94
28_R36_E0.6680.94
93_A160_V0.6660.93
144_V148_T0.6650.93
86_L89_I0.6600.93
133_S136_M0.6590.93
30_I48_F0.6590.93
73_E91_I0.6580.93
140_F143_K0.6560.93
91_I103_F0.6540.93
40_I66_Y0.6500.93
85_T88_T0.6490.93
29_V64_V0.6480.92
42_Y89_I0.6450.92
85_T89_I0.6340.92
56_Y136_M0.6240.91
147_E150_S0.6200.91
81_L84_F0.6190.91
42_Y160_V0.6180.91
36_E53_A0.6150.90
75_L79_E0.6150.90
84_F87_S0.6110.90
62_M136_M0.6040.90
26_F64_V0.6000.89
153_F156_L0.6000.89
41_V157_N0.5950.89
146_P149_L0.5930.89
134_N137_P0.5920.89
35_D43_R0.5910.89
39_Y53_A0.5900.89
111_R130_N0.5870.88
54_F144_V0.5870.88
21_Q28_R0.5790.88
60_H124_H0.5780.88
41_V153_F0.5760.87
80_A85_T0.5750.87
30_I66_Y0.5730.87
113_A126_V0.5720.87
103_F107_V0.5620.86
148_T152_T0.5620.86
34_N38_N0.5610.86
84_F88_T0.5580.86
58_T152_T0.5580.86
104_N126_V0.5530.85
128_R131_G0.5520.85
56_Y116_G0.5510.85
56_Y106_G0.5490.85
132_D137_P0.5470.85
42_Y49_I0.5470.85
133_S137_P0.5450.84
78_D81_L0.5440.84
102_G115_A0.5430.84
152_T155_K0.5390.84
25_L29_V0.5370.83
154_K157_N0.5370.83
97_I155_K0.5370.83
100_P103_F0.5330.83
147_E151_D0.5330.83
46_H78_D0.5310.83
70_P73_E0.5310.83
109_I115_A0.5300.83
144_V147_E0.5260.82
97_I100_P0.5250.82
55_P65_P0.5230.82
130_N133_S0.5200.81
141_N144_V0.5180.81
36_E40_I0.5170.81
106_G126_V0.5100.80
150_S157_N0.5060.80
90_A93_A0.5050.80
75_L83_I0.5050.80
95_R100_P0.5040.79
83_I86_L0.5010.79
94_I98_Y0.5000.79
71_S109_I0.5000.79
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3anoA 4 0.9591 100 0.221 Contact Map
3l7xA 2 0.9064 100 0.299 Contact Map
3ksvA 2 0.8246 100 0.319 Contact Map
3lb5A 2 0.8012 100 0.342 Contact Map
3imiA 2 0.8246 100 0.353 Contact Map
2eo4A 2 0.848 100 0.364 Contact Map
1y23A 2 0.8129 100 0.368 Contact Map
3o0mA 2 0.807 100 0.369 Contact Map
1emsA 3 0.848 100 0.387 Contact Map
3r6fA 2 0.7602 100 0.393 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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