Q980K5 - SULSO - GREMLIN Contacts

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Q980K5 - RNase L inhibitor

UniProt:	Q980K5	Sequences: MRVAVINYDFCKPDKCNLECINFCPVDRSGGKAIELSEIVKGKPVIYEETCIGCGICVKKCPYEAISIVNLPDELEGEVIHRYKVNGFKLFGLPTPKNNTILGVLGKNGVGKTTVLKILAGEIIPNFGDPNSKVGKDEVLKRFRGKEIYNYFKELYSNELKIVHKIQYVEYASKFLKGTVNEILTKIDERGKKDEVKELLNMTNLWNKDANILSGGGLQRLLVAASLLREADVYIFDEPSSYLDVRERMNMAKAIRELLKNKYVIVVDHDLIVLDYLTDLIHIIYGESSVYGRVSKSYAARVGINNFLKGYLPAENMKIRPDEIKFMLKEVSDLDLSKDLKTKMKWTKIIKKLGDFQLVVDNGEAKEGEIIGILGPNGIGKTTFARILVGEITADEGSVTPEKQILSYKPQRIFPNYDGTVQQYLENASKDALSTSSWFFEEVTKRLNLHRLLESNVNDLSGGELQKLYIAATLAKEADLYVLDEPSSYLDVEERYIVAKAIKRVTRERKAVTFIIDHDLSIHDYIADRIIVFKGEPEKAGLATSPVTLKTGMNEFLRELEVTFRRDAETGRPRVNKIGSYLDRVQKERGDYYSMVLSTQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	600 (504)
Sequences:	659 (373)
Seq/√Len:	16.6

HALSA - Q9HMC1
SULSO - Q980K5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
285_Y	288_S	5.512	1.00
280_L	284_I	5.011	1.00
291_Y	294_V	4.293	1.00
281_I	284_I	4.175	1.00
280_L	285_Y	4.158	1.00
280_L	283_I	4.015	1.00
281_I	285_Y	4.011	1.00
346_W	351_K	3.913	1.00
365_A	368_G	3.826	1.00
291_Y	298_Y	3.799	1.00
347_T	351_K	3.793	1.00
286_G	292_G	3.413	0.99
198_E	203_T	3.369	0.99
285_Y	289_S	3.274	0.99
286_G	290_V	3.213	0.99
286_G	289_S	3.135	0.99
285_Y	290_V	3.080	0.99
385_A	516_I	3.036	0.99
354_G	363_G	2.950	0.98
124_I	139_V	2.896	0.98
292_G	297_S	2.888	0.98
287_E	290_V	2.747	0.97
230_E	262_K	2.742	0.97
103_G	532_V	2.737	0.97
284_I	287_E	2.707	0.97
196_V	228_L	2.700	0.97
292_G	295_S	2.693	0.97
287_E	291_Y	2.693	0.97
286_G	291_Y	2.673	0.97
291_Y	295_S	2.499	0.95
346_W	349_I	2.492	0.95
281_I	288_S	2.490	0.95
284_I	288_S	2.460	0.95
288_S	291_Y	2.441	0.95
291_Y	296_K	2.393	0.94
352_K	357_Q	2.387	0.94
170_E	173_S	2.350	0.93
499_A	502_I	2.339	0.93
285_Y	291_Y	2.330	0.93
188_D	191_G	2.327	0.93
280_L	288_S	2.255	0.92
356_F	363_G	2.251	0.92
291_Y	297_S	2.250	0.92
281_I	286_G	2.231	0.91
280_L	286_G	2.201	0.91
407_S	473_T	2.166	0.90
419_G	424_Y	2.115	0.89
284_I	289_S	2.104	0.89
418_D	458_N	2.075	0.88
209_D	212_I	2.067	0.88
172_A	222_L	2.046	0.87
180_V	184_L	2.027	0.87
285_Y	292_G	2.001	0.86
358_L	361_D	1.998	0.86
46_I	51_C	1.993	0.86
292_G	299_A	1.988	0.86
292_G	298_Y	1.981	0.85
294_V	300_A	1.981	0.85
291_Y	299_A	1.977	0.85
283_I	286_G	1.975	0.85
294_V	297_S	1.963	0.85
420_T	423_Q	1.957	0.85
354_G	368_G	1.942	0.84
363_G	368_G	1.925	0.84
153_K	159_E	1.923	0.84
506_T	513_T	1.919	0.84
284_I	290_V	1.908	0.83
292_G	296_K	1.901	0.83
287_E	292_G	1.870	0.82
26_V	31_G	1.848	0.81
503_K	526_I	1.831	0.80
467_K	494_E	1.819	0.80
434_S	438_W	1.812	0.80
290_V	298_Y	1.804	0.79
129_D	138_E	1.794	0.79
173_S	177_K	1.793	0.79
348_K	361_D	1.793	0.79
283_I	288_S	1.775	0.78
48_E	51_C	1.774	0.78
353_L	356_F	1.755	0.77
294_V	298_Y	1.750	0.77
305_N	310_G	1.729	0.76
247_E	495_R	1.712	0.76
295_S	298_Y	1.672	0.74
197_K	203_T	1.670	0.74
440_F	444_T	1.657	0.73
288_S	292_G	1.626	0.72
295_S	300_A	1.603	0.71
290_V	299_A	1.586	0.70
295_S	301_R	1.569	0.69
107_K	249_M	1.566	0.69
349_I	353_L	1.559	0.68
283_I	289_S	1.544	0.68
538_E	541_G	1.542	0.68
309_K	533_F	1.530	0.67
427_N	431_D	1.522	0.66
249_M	271_L	1.516	0.66
48_E	53_G	1.514	0.66
291_Y	300_A	1.512	0.66
54_C	57_C	1.500	0.65
283_I	290_V	1.487	0.65
374_L	385_A	1.468	0.64
486_P	490_L	1.460	0.63
247_E	252_A	1.446	0.62
202_M	271_L	1.444	0.62
495_R	503_K	1.441	0.62
105_L	530_I	1.439	0.62
270_D	462_G	1.438	0.62
294_V	299_A	1.434	0.62
310_G	320_R	1.431	0.62
173_S	178_G	1.426	0.61
324_I	340_L	1.419	0.61
252_A	495_R	1.417	0.61
520_L	527_A	1.412	0.60
104_V	284_I	1.410	0.60
166_I	172_A	1.400	0.60
152_F	156_Y	1.396	0.60
193_K	206_W	1.394	0.59
343_K	353_L	1.387	0.59
537_P	541_G	1.370	0.58
374_L	523_H	1.370	0.58
290_V	294_V	1.359	0.57
156_Y	159_E	1.355	0.57
196_V	227_L	1.355	0.57
223_V	236_F	1.348	0.57
305_N	316_N	1.338	0.56
272_I	523_H	1.333	0.56
165_K	169_V	1.330	0.56
284_I	291_Y	1.318	0.55
361_D	365_A	1.308	0.54
250_N	253_K	1.304	0.54
292_G	300_A	1.301	0.54
154_E	480_L	1.300	0.54
351_K	363_G	1.296	0.54
353_L	386_R	1.271	0.52
247_E	503_K	1.269	0.52
297_S	300_A	1.263	0.52
147_E	150_N	1.257	0.51
197_K	206_W	1.251	0.51
310_G	316_N	1.251	0.51
280_L	290_V	1.251	0.51
107_K	271_L	1.248	0.51
273_V	294_V	1.248	0.51
306_N	313_P	1.244	0.51
392_I	448_N	1.243	0.51
89_K	382_T	1.241	0.51
57_C	61_C	1.241	0.51
320_R	326_F	1.236	0.50
346_W	353_L	1.235	0.50
346_W	363_G	1.234	0.50
252_A	503_K	1.233	0.50
295_S	299_A	1.232	0.50
193_K	197_K	1.227	0.50
200_L	227_L	1.220	0.49
226_S	506_T	1.214	0.49
495_R	526_I	1.211	0.49
141_K	212_I	1.205	0.48
335_D	340_L	1.205	0.48
107_K	110_V	1.204	0.48
165_K	170_E	1.203	0.48
296_K	299_A	1.199	0.48
486_P	491_D	1.198	0.48
224_A	228_L	1.188	0.47
226_S	255_I	1.185	0.47
220_R	247_E	1.181	0.47
58_V	408_Y	1.178	0.47
280_L	287_E	1.176	0.47
351_K	395_D	1.173	0.47
332_S	335_D	1.168	0.46
484_D	491_D	1.167	0.46
511_A	531_I	1.164	0.46
100_T	417_Y	1.162	0.46
280_L	289_S	1.161	0.46
346_W	356_F	1.160	0.46
360_V	363_G	1.160	0.46
153_K	156_Y	1.157	0.46
392_I	479_D	1.157	0.46
498_V	501_A	1.156	0.46
502_I	516_I	1.155	0.45
363_G	367_E	1.153	0.45
174_K	264_V	1.151	0.45
290_V	297_S	1.149	0.45
134_V	138_E	1.149	0.45
303_G	310_G	1.146	0.45
148_I	175_F	1.144	0.45
414_F	480_L	1.136	0.44
117_K	134_V	1.133	0.44
184_L	188_D	1.129	0.44
122_E	376_P	1.129	0.44
27_D	44_P	1.119	0.43
283_I	287_E	1.115	0.43
143_F	454_E	1.113	0.43
344_M	351_K	1.103	0.42
155_L	159_E	1.102	0.42
54_C	61_C	1.097	0.42
354_G	365_A	1.097	0.42
227_L	236_F	1.095	0.42
300_A	303_G	1.093	0.42
192_K	228_L	1.092	0.42
168_Y	489_Y	1.086	0.41
306_N	309_K	1.081	0.41
240_S	453_L	1.081	0.41
324_I	329_K	1.075	0.41
200_L	222_L	1.074	0.41
61_C	65_A	1.072	0.41
252_A	308_L	1.064	0.40
73_D	496_Y	1.064	0.40
286_G	295_S	1.063	0.40
181_N	185_T	1.061	0.40
442_E	508_E	1.061	0.40
357_Q	363_G	1.051	0.39
127_F	133_K	1.051	0.39
51_C	61_C	1.050	0.39
358_L	363_G	1.047	0.39
288_S	297_S	1.034	0.39
310_G	315_E	1.033	0.38
51_C	54_C	1.030	0.38
120_A	536_E	1.027	0.38
485_E	491_D	1.026	0.38
477_E	532_V	1.023	0.38
498_V	512_V	1.023	0.38
517_D	522_I	1.021	0.38
183_I	225_A	1.016	0.38
344_M	420_T	1.010	0.37
196_V	249_M	1.006	0.37
120_A	361_D	1.005	0.37
413_I	470_I	1.005	0.37
430_K	437_S	0.997	0.36
47_Y	50_T	0.997	0.36
28_R	166_I	0.995	0.36
103_G	112_K	0.994	0.36
379_I	511_A	0.994	0.36
120_A	235_I	0.993	0.36
152_F	159_E	0.991	0.36
349_I	352_K	0.991	0.36
491_D	518_H	0.990	0.36
307_F	315_E	0.986	0.36
84_K	488_S	0.982	0.36
347_T	356_F	0.981	0.36
196_V	471_A	0.981	0.36
82_R	89_K	0.980	0.36
182_E	185_T	0.975	0.35
385_A	406_L	0.973	0.35
426_E	444_T	0.972	0.35
320_R	324_I	0.971	0.35
159_E	223_V	0.968	0.35
110_V	283_I	0.967	0.35
144_R	522_I	0.962	0.35
353_L	363_G	0.961	0.35
484_D	490_L	0.960	0.34
77_G	428_A	0.957	0.34
336_L	339_D	0.955	0.34
185_T	193_K	0.955	0.34
500_K	526_I	0.953	0.34
227_L	254_A	0.950	0.34
76_E	384_F	0.950	0.34
176_L	233_V	0.947	0.34
443_V	475_A	0.947	0.34
116_L	220_R	0.947	0.34
198_E	420_T	0.946	0.34
297_S	301_R	0.944	0.34
421_V	457_V	0.940	0.33
288_S	294_V	0.939	0.33
385_A	408_Y	0.939	0.33
160_L	163_V	0.938	0.33
512_V	522_I	0.937	0.33
38_E	49_E	0.932	0.33
304_I	310_G	0.929	0.33
58_V	63_Y	0.928	0.33
445_K	450_H	0.922	0.32
317_M	323_E	0.920	0.32
245_V	533_F	0.917	0.32
326_F	329_K	0.915	0.32
95_T	228_L	0.912	0.32
448_N	451_R	0.911	0.32
47_Y	51_C	0.910	0.32
196_V	230_E	0.910	0.32
352_K	356_F	0.910	0.32
158_N	531_I	0.908	0.32
314_A	317_M	0.904	0.32
340_L	349_I	0.903	0.31
164_H	167_Q	0.903	0.31
181_N	193_K	0.901	0.31
303_G	493_E	0.899	0.31
281_I	287_E	0.895	0.31
349_I	399_V	0.893	0.31
179_T	185_T	0.889	0.31
28_R	515_I	0.888	0.31
308_L	315_E	0.885	0.31
271_L	495_R	0.884	0.31
271_L	503_K	0.883	0.30
54_C	65_A	0.881	0.30
316_N	320_R	0.880	0.30
116_L	235_I	0.875	0.30
46_I	53_G	0.873	0.30
111_G	114_T	0.871	0.30
44_P	47_Y	0.868	0.30
222_L	467_K	0.864	0.30
342_T	353_L	0.864	0.30
394_A	397_G	0.864	0.30
386_R	469_Y	0.863	0.29
171_Y	406_L	0.863	0.29
309_K	323_E	0.861	0.29
54_C	62_P	0.858	0.29
38_E	45_V	0.857	0.29
361_D	368_G	0.857	0.29
348_K	362_N	0.856	0.29
119_L	504_R	0.856	0.29
350_I	360_V	0.856	0.29
347_T	353_L	0.855	0.29
174_K	177_K	0.851	0.29
282_H	298_Y	0.850	0.29
103_G	108_N	0.850	0.29
288_S	295_S	0.850	0.29
31_G	52_I	0.849	0.29
452_L	455_S	0.848	0.29
222_L	343_K	0.848	0.29
312_L	317_M	0.847	0.29
399_V	499_A	0.846	0.29
233_V	473_T	0.845	0.29
352_K	395_D	0.845	0.29
373_I	428_A	0.842	0.28
292_G	301_R	0.842	0.28
126_N	147_E	0.840	0.28
247_E	526_I	0.840	0.28
288_S	298_Y	0.839	0.28
57_C	62_P	0.838	0.28
447_L	470_I	0.838	0.28
51_C	62_P	0.835	0.28
199_L	250_N	0.835	0.28
402_E	470_I	0.834	0.28
537_P	540_A	0.834	0.28
140_L	149_Y	0.829	0.28
349_I	361_D	0.829	0.28
178_G	188_D	0.828	0.28
120_A	273_V	0.827	0.28
184_L	224_A	0.827	0.28
99_N	353_L	0.825	0.28
304_I	308_L	0.818	0.27
86_N	109_G	0.815	0.27
112_K	499_A	0.815	0.27
79_V	470_I	0.815	0.27
150_N	509_R	0.814	0.27
182_E	261_N	0.814	0.27
27_D	50_T	0.813	0.27
304_I	316_N	0.812	0.27
435_T	459_D	0.811	0.27
485_E	490_L	0.809	0.27
57_C	63_Y	0.808	0.27
307_F	310_G	0.808	0.27
374_L	530_I	0.808	0.27
282_H	285_Y	0.806	0.27
484_D	518_H	0.806	0.27
199_L	257_E	0.805	0.27
252_A	526_I	0.803	0.27
483_L	488_S	0.803	0.27
282_H	291_Y	0.803	0.27
73_D	408_Y	0.793	0.26
56_I	61_C	0.792	0.26
136_K	156_Y	0.792	0.26
234_Y	264_V	0.791	0.26
27_D	56_I	0.790	0.26
419_G	427_N	0.790	0.26
334_L	417_Y	0.790	0.26
150_N	159_E	0.789	0.26
51_C	57_C	0.785	0.26
240_S	487_S	0.785	0.26
334_L	337_S	0.785	0.26
374_L	436_S	0.785	0.26
391_E	408_Y	0.784	0.26
343_K	348_K	0.784	0.26
536_E	539_K	0.784	0.26
241_S	489_Y	0.782	0.26
150_N	153_K	0.780	0.26
505_V	534_K	0.778	0.25
310_G	313_P	0.775	0.25
164_H	175_F	0.775	0.25
428_A	431_D	0.774	0.25
266_V	516_I	0.774	0.25
281_I	289_S	0.769	0.25
26_V	52_I	0.769	0.25
73_D	311_Y	0.768	0.25
113_T	266_V	0.767	0.25
202_M	220_R	0.767	0.25
107_K	376_P	0.765	0.25
435_T	468_L	0.765	0.25
373_I	531_I	0.765	0.25
299_A	302_V	0.765	0.25
147_E	495_R	0.764	0.25
424_Y	428_A	0.763	0.25
240_S	307_F	0.762	0.25
186_K	260_K	0.758	0.25
495_R	506_T	0.755	0.24
281_I	347_T	0.755	0.24
448_N	497_I	0.755	0.24
290_V	300_A	0.755	0.24
62_P	65_A	0.754	0.24
199_L	203_T	0.754	0.24
46_I	66_I	0.753	0.24
95_T	262_K	0.752	0.24
172_A	178_G	0.752	0.24
200_L	224_A	0.749	0.24
255_I	264_V	0.748	0.24
486_P	518_H	0.745	0.24
328_L	333_D	0.745	0.24
247_E	346_W	0.744	0.24
166_I	170_E	0.743	0.24
124_I	136_K	0.743	0.24
490_L	518_H	0.742	0.24
372_G	524_D	0.742	0.24
343_K	349_I	0.742	0.24
29_S	196_V	0.740	0.24
278_T	521_S	0.740	0.24
429_S	475_A	0.739	0.24
55_G	62_P	0.738	0.24
62_P	66_I	0.738	0.24
342_T	402_E	0.736	0.24
55_G	61_C	0.736	0.24
220_R	505_V	0.735	0.24
280_L	291_Y	0.735	0.24
173_S	176_L	0.734	0.24
298_Y	327_M	0.734	0.24
347_T	352_K	0.733	0.24
242_Y	487_S	0.733	0.24
140_L	155_L	0.732	0.23
321_P	534_K	0.731	0.23
326_F	330_E	0.730	0.23
247_E	446_R	0.727	0.23
56_I	71_L	0.726	0.23
319_I	324_I	0.726	0.23
196_V	254_A	0.724	0.23
426_E	430_K	0.723	0.23
456_N	459_D	0.723	0.23
160_L	386_R	0.723	0.23
179_T	202_M	0.720	0.23
150_N	249_M	0.720	0.23
386_R	414_F	0.719	0.23
30_G	58_V	0.719	0.23
138_E	445_K	0.718	0.23
61_C	66_I	0.716	0.23
506_T	526_I	0.713	0.23
510_K	514_F	0.713	0.23
252_A	271_L	0.711	0.23
51_C	55_G	0.710	0.23
196_V	224_A	0.710	0.23
65_A	68_I	0.710	0.23
273_V	277_L	0.709	0.23
51_C	65_A	0.708	0.22
59_K	62_P	0.705	0.22
378_G	512_V	0.705	0.22
363_G	366_K	0.704	0.22
417_Y	424_Y	0.704	0.22
181_N	393_T	0.704	0.22
53_G	63_Y	0.703	0.22
500_K	503_K	0.701	0.22
308_L	320_R	0.697	0.22
61_C	71_L	0.696	0.22
239_P	382_T	0.696	0.22
291_Y	301_R	0.696	0.22
169_V	173_S	0.696	0.22
287_E	296_K	0.691	0.22
70_N	144_R	0.691	0.22
302_V	311_Y	0.688	0.22
161_K	164_H	0.688	0.22
83_Y	330_E	0.687	0.22
44_P	423_Q	0.686	0.22
354_G	413_I	0.685	0.22
249_M	252_A	0.684	0.22
51_C	59_K	0.683	0.21
468_L	472_A	0.683	0.21
210_A	346_W	0.683	0.21
137_D	225_A	0.683	0.21
137_D	448_N	0.682	0.21
255_I	513_T	0.681	0.21
339_D	342_T	0.679	0.21
31_G	314_A	0.679	0.21
344_M	349_I	0.677	0.21
188_D	192_K	0.677	0.21
174_K	178_G	0.676	0.21
227_L	471_A	0.676	0.21
27_D	531_I	0.675	0.21
334_L	340_L	0.673	0.21
305_N	326_F	0.671	0.21
426_E	434_S	0.670	0.21
128_G	133_K	0.670	0.21
359_V	388_L	0.669	0.21
448_N	467_K	0.669	0.21
62_P	68_I	0.668	0.21
346_W	352_K	0.667	0.21
478_A	481_Y	0.666	0.21
535_G	541_G	0.666	0.21
168_Y	173_S	0.664	0.21
81_H	326_F	0.664	0.21
304_I	320_R	0.664	0.21
385_A	482_V	0.664	0.21
298_Y	301_R	0.663	0.21
329_K	335_D	0.663	0.21
135_G	154_E	0.663	0.21
210_A	344_M	0.662	0.21
226_S	253_K	0.661	0.21
447_L	500_K	0.658	0.20
77_G	265_I	0.658	0.20
130_P	134_V	0.658	0.20
354_G	360_V	0.657	0.20
247_E	271_L	0.657	0.20
263_Y	506_T	0.656	0.20
103_G	126_N	0.654	0.20
346_W	368_G	0.651	0.20
377_N	463_G	0.650	0.20
137_D	327_M	0.650	0.20
117_K	235_I	0.650	0.20
73_D	309_K	0.649	0.20
138_E	200_L	0.648	0.20
133_K	136_K	0.647	0.20
467_K	501_A	0.646	0.20
81_H	90_L	0.645	0.20
307_F	320_R	0.645	0.20
102_L	256_R	0.643	0.20
155_L	206_W	0.643	0.20
351_K	354_G	0.642	0.20
182_E	195_E	0.641	0.20
353_L	361_D	0.641	0.20
187_I	298_Y	0.641	0.20
193_K	441_E	0.640	0.20
441_E	509_R	0.640	0.20
45_V	58_V	0.640	0.20
502_I	524_D	0.640	0.20
333_D	337_S	0.639	0.20
186_K	398_S	0.639	0.20
253_K	325_K	0.639	0.20
397_G	406_L	0.638	0.20
45_V	201_N	0.638	0.20
339_D	398_S	0.638	0.20
113_T	220_R	0.637	0.20
523_H	530_I	0.635	0.20
301_R	449_L	0.635	0.20
184_L	353_L	0.633	0.20
155_L	226_S	0.633	0.20
485_E	518_H	0.632	0.20
349_I	354_G	0.632	0.20
112_K	377_N	0.632	0.20
113_T	260_K	0.630	0.19
103_G	258_L	0.628	0.19
477_E	510_K	0.628	0.19
117_K	122_E	0.627	0.19
439_F	443_V	0.627	0.19
126_N	532_V	0.627	0.19
470_I	476_K	0.625	0.19
102_L	239_P	0.624	0.19
54_C	63_Y	0.624	0.19
119_L	148_I	0.624	0.19
371_I	382_T	0.621	0.19
301_R	304_I	0.620	0.19
152_F	496_Y	0.620	0.19
54_C	66_I	0.620	0.19
308_L	312_L	0.619	0.19
259_L	264_V	0.619	0.19
120_A	164_H	0.618	0.19
129_D	139_V	0.618	0.19
256_R	265_I	0.616	0.19
48_E	57_C	0.615	0.19
108_N	112_K	0.615	0.19
348_K	401_P	0.615	0.19
280_L	418_D	0.615	0.19
349_I	387_I	0.615	0.19
284_I	294_V	0.614	0.19
225_A	471_A	0.614	0.19
521_S	525_Y	0.614	0.19
370_I	483_L	0.614	0.19
194_D	260_K	0.613	0.19
74_E	146_K	0.613	0.19
304_I	319_I	0.612	0.19
391_E	397_G	0.611	0.19
30_G	34_I	0.610	0.19
54_C	71_L	0.610	0.19
127_F	130_P	0.609	0.19
311_Y	374_L	0.609	0.19
354_G	367_E	0.609	0.19
330_E	335_D	0.606	0.19
354_G	361_D	0.606	0.19
310_G	318_K	0.606	0.19
156_Y	391_E	0.605	0.19
496_Y	512_V	0.604	0.18
113_T	453_L	0.604	0.18
147_E	503_K	0.604	0.18
397_G	471_A	0.603	0.18
235_I	242_Y	0.602	0.18
103_G	414_F	0.600	0.18
53_G	57_C	0.599	0.18
57_C	65_A	0.598	0.18
308_L	318_K	0.598	0.18
286_G	294_V	0.598	0.18
344_M	347_T	0.598	0.18
274_L	390_G	0.596	0.18
130_P	133_K	0.595	0.18
27_D	47_Y	0.594	0.18
85_V	253_K	0.594	0.18
120_A	436_S	0.594	0.18
48_E	62_P	0.594	0.18
193_K	228_L	0.593	0.18
232_D	405_I	0.591	0.18
489_Y	525_Y	0.591	0.18
342_T	345_K	0.591	0.18
147_E	247_E	0.591	0.18
138_E	502_I	0.590	0.18
352_K	360_V	0.589	0.18
94_P	97_K	0.589	0.18
116_L	265_I	0.589	0.18
191_G	264_V	0.588	0.18
340_L	351_K	0.586	0.18
310_G	314_A	0.585	0.18
61_C	68_I	0.585	0.18
457_V	468_L	0.584	0.18
265_I	319_I	0.584	0.18
116_L	298_Y	0.583	0.18
131_N	309_K	0.582	0.18
376_P	495_R	0.580	0.18
269_H	377_N	0.579	0.18
166_I	222_L	0.579	0.18
267_V	503_K	0.577	0.18
131_N	387_I	0.577	0.18
477_E	523_H	0.576	0.18
422_Q	454_E	0.576	0.18
115_V	124_I	0.576	0.18
513_T	530_I	0.573	0.17
73_D	84_K	0.572	0.17
273_V	508_E	0.572	0.17
152_F	236_F	0.571	0.17
306_N	314_A	0.570	0.17
116_L	371_I	0.569	0.17
298_Y	314_A	0.569	0.17
348_K	512_V	0.568	0.17
426_E	437_S	0.568	0.17
282_H	290_V	0.568	0.17
73_D	533_F	0.568	0.17
505_V	511_A	0.568	0.17
331_V	339_D	0.567	0.17
141_K	209_D	0.566	0.17
117_K	447_L	0.566	0.17
234_Y	274_L	0.565	0.17
424_Y	427_N	0.562	0.17
350_I	357_Q	0.561	0.17
113_T	527_A	0.559	0.17
222_L	520_L	0.559	0.17
129_D	132_S	0.559	0.17
434_S	440_F	0.558	0.17
106_G	111_G	0.558	0.17
341_K	355_D	0.557	0.17
308_L	316_N	0.555	0.17
80_I	221_L	0.554	0.17
91_F	102_L	0.554	0.17
172_A	176_L	0.554	0.17
113_T	132_S	0.553	0.17
503_K	514_F	0.552	0.17
390_G	479_D	0.552	0.17
267_V	502_I	0.552	0.17
249_M	253_K	0.551	0.17
113_T	450_H	0.549	0.17
34_I	63_Y	0.549	0.17
44_P	56_I	0.548	0.17
327_M	451_R	0.548	0.17
58_V	70_N	0.548	0.17
142_R	200_L	0.548	0.17
378_G	522_I	0.547	0.17
253_K	450_H	0.547	0.17
324_I	454_E	0.547	0.17
386_R	391_E	0.544	0.16
207_N	228_L	0.544	0.16
370_I	502_I	0.542	0.16
57_C	66_I	0.542	0.16
179_T	222_L	0.541	0.16
69_V	110_V	0.541	0.16
514_F	520_L	0.540	0.16
233_V	353_L	0.540	0.16
354_G	358_L	0.540	0.16
51_C	68_I	0.539	0.16
375_G	381_K	0.539	0.16
202_M	495_R	0.539	0.16
480_L	499_A	0.538	0.16
208_K	212_I	0.538	0.16
264_V	513_T	0.537	0.16
193_K	223_V	0.537	0.16
308_L	326_F	0.536	0.16
407_S	476_K	0.536	0.16
177_K	402_E	0.535	0.16
449_L	500_K	0.535	0.16
103_G	526_I	0.535	0.16
26_V	29_S	0.531	0.16
196_V	277_L	0.531	0.16
142_R	227_L	0.531	0.16
455_S	515_I	0.530	0.16
143_F	483_L	0.530	0.16
345_K	451_R	0.530	0.16
316_N	324_I	0.529	0.16
103_G	502_I	0.529	0.16
69_V	522_I	0.529	0.16
48_E	54_C	0.527	0.16
54_C	68_I	0.526	0.16
48_E	55_G	0.525	0.16
57_C	68_I	0.525	0.16
189_E	399_V	0.525	0.16
343_K	351_K	0.524	0.16
463_G	519_D	0.524	0.16
190_R	230_E	0.523	0.16
310_G	319_I	0.522	0.16
496_Y	533_F	0.521	0.16
498_V	522_I	0.521	0.16
304_I	307_F	0.521	0.16
224_A	444_T	0.521	0.16
90_L	304_I	0.521	0.16
124_I	127_F	0.521	0.16
377_N	461_S	0.520	0.16
152_F	474_L	0.520	0.16
520_L	524_D	0.520	0.16
197_K	250_N	0.520	0.16
355_D	360_V	0.519	0.16
468_L	473_T	0.519	0.16
204_N	449_L	0.518	0.16
202_M	247_E	0.518	0.16
95_T	249_M	0.518	0.16
369_E	529_R	0.517	0.16
324_I	330_E	0.516	0.16
264_V	376_P	0.516	0.16
409_K	466_Q	0.515	0.16
180_V	213_L	0.515	0.16
315_E	318_K	0.514	0.15
351_K	387_I	0.514	0.15
135_G	226_S	0.513	0.15
192_K	195_E	0.513	0.15
81_H	94_P	0.512	0.15
332_S	340_L	0.512	0.15
113_T	384_F	0.511	0.15
109_G	116_L	0.510	0.15
224_A	425_L	0.510	0.15
51_C	66_I	0.508	0.15
267_V	308_L	0.508	0.15
536_E	540_A	0.508	0.15
444_T	453_L	0.508	0.15
137_D	206_W	0.507	0.15
315_E	331_V	0.507	0.15
355_D	393_T	0.507	0.15
249_M	258_L	0.506	0.15
495_R	500_K	0.505	0.15
220_R	467_K	0.505	0.15
83_Y	326_F	0.504	0.15
105_L	327_M	0.504	0.15
305_N	324_I	0.503	0.15
446_R	467_K	0.503	0.15
284_I	382_T	0.502	0.15
180_V	187_I	0.502	0.15
468_L	475_A	0.502	0.15
302_V	306_N	0.501	0.15
246_R	525_Y	0.501	0.15
168_Y	172_A	0.501	0.15
124_I	135_G	0.500	0.15
290_V	295_S	0.500	0.15

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3bk7A	1	0.9783	100	0.36	Contact Map
3j16B	1	0.9817	100	0.372	Contact Map
3ozxA	1	0.8583	100	0.534	Contact Map
1yqtA	1	0.8567	100	0.545	Contact Map
4finA	2	0.8083	100	0.645	Contact Map
2iw3A	2	0.82	100	0.649	Contact Map
4q9hA	1	0.8767	100	0.683	Contact Map
3ux8A	2	0.6983	100	0.688	Contact Map
4f4cA	1	0.8533	100	0.689	Contact Map
2vf7A	2	0.8533	100	0.735	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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