Q980I2 - SULSO - GREMLIN Contacts

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Q980I2 - DNA helicase

UniProt:	Q980I2	Sequences: MELREWQSKIAEKIVEALRNNFLVSLQAPTGSGKTLFALYTALKVKPKVAFVVRTHNEFFPVYRELSLHFKDKKYGFLVGKSSACVFSSSDVDAQDIYCNGCEIFNASAVTVTDSPKVSLNKLKEEGKKLGFCPYYSLLETIKTADVILLTYPYLFIPWLRESLDINWEDYVVIVDEAHNIENVSNIEEKKLNKRIIEMAISQSHSQNVKVILERLKENVEKAVYSEDKYILIEKDKLDNILPSNEEIEILSEEYDEIRKIMIKNKTVSRNYLGSILRFFDLVNDEGIRVFSYSGSLIAKYIIPSYFTDILNDEKITYMLMSGTMQPLDYLRNIIGIKRKILYIDAEKVMKKRLTGTYECLISIDVTTTYSLRSEQMARKYASYLLKIFYNSRRHVLAIFPSYEFMRIVSKFLNIRYLAEDTETSIEEIMSNLKKEKTIIMGIARGKLAEGIEIVENGSSLISDVAMVGIPYPPIDDYLKIRVEEISKILKKDISNELISIQALIAVKQSIGRAIRGPTDNATIWLLDKRYDSLWWKKELNCLNARKIKL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	550 (528)
Sequences:	4204 (3193)
Seq/√Len:	139.0

ECOLI - DING YOAA
BACSU - DING YPVA
HALSA - Q9HMP9 Q9HQ08 Q9HMM1
SULSO - Q980I2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
351_K	354_L	6.427	1.00
379_R	412_F	4.506	1.00
400_F	409_V	4.298	1.00
178_A	320_L	4.167	1.00
42_A	174_I	4.008	1.00
413_L	441_M	3.952	1.00
385_L	466_A	3.916	1.00
155_L	175_V	3.669	1.00
389_F	396_V	3.623	1.00
400_F	441_M	3.276	1.00
5_E	9_K	3.274	1.00
18_L	172_V	3.271	1.00
10_I	26_L	3.255	1.00
85_C	133_C	3.133	1.00
392_S	396_V	3.100	1.00
486_I	491_K	3.008	1.00
108_S	111_T	2.913	1.00
332_R	343_Y	2.898	1.00
388_I	525_W	2.807	1.00
514_A	522_A	2.776	1.00
395_H	463_S	2.746	1.00
66_L	75_Y	2.690	1.00
17_A	24_V	2.626	1.00
403_Y	443_I	2.544	1.00
385_L	398_A	2.486	1.00
272_Y	275_S	2.486	1.00
42_A	49_V	2.382	1.00
13_K	344_I	2.348	1.00
273_L	279_F	2.306	1.00
382_A	412_F	2.279	1.00
76_G	145_A	2.268	1.00
449_A	510_S	2.260	1.00
104_I	108_S	2.258	1.00
270_R	274_G	2.251	1.00
279_F	283_V	2.218	1.00
10_I	321_M	2.199	1.00
404_E	408_I	2.186	1.00
526_L	531_Y	2.161	1.00
511_I	524_I	2.157	1.00
175_V	181_I	2.149	1.00
431_S	435_K	2.104	1.00
287_G	290_V	2.070	1.00
455_V	517_G	2.056	1.00
384_Y	527_L	2.055	1.00
35_T	62_V	2.040	1.00
16_E	20_N	2.037	1.00
464_D	525_W	2.025	1.00
6_W	346_A	2.022	1.00
221_E	224_V	2.015	1.00
274_G	279_F	1.998	1.00
22_F	342_L	1.988	1.00
272_Y	279_F	1.987	1.00
389_F	439_I	1.952	1.00
388_I	464_D	1.942	1.00
209_V	212_I	1.906	1.00
396_V	464_D	1.889	1.00
394_R	457_N	1.885	1.00
417_Y	420_E	1.879	1.00
217_K	221_E	1.865	1.00
266_K	269_S	1.863	1.00
180_N	450_E	1.856	1.00
457_N	463_S	1.844	1.00
8_S	12_E	1.843	1.00
331_L	335_I	1.841	1.00
491_K	497_E	1.822	1.00
191_K	298_I	1.818	1.00
504_L	540_L	1.801	1.00
507_V	526_L	1.798	1.00
276_I	279_F	1.785	1.00
312_N	320_L	1.776	1.00
400_F	406_M	1.769	1.00
221_E	225_Y	1.758	1.00
417_Y	421_D	1.754	1.00
122_K	127_G	1.748	1.00
484_E	487_S	1.725	1.00
485_E	489_I	1.716	1.00
25_S	332_R	1.716	1.00
63_Y	77_F	1.708	1.00
382_A	409_V	1.700	1.00
288_I	291_F	1.674	1.00
484_E	488_K	1.662	1.00
406_M	441_M	1.654	1.00
270_R	273_L	1.634	1.00
273_L	276_I	1.634	1.00
326_Q	345_D	1.632	1.00
17_A	317_T	1.626	1.00
496_N	535_W	1.624	1.00
52_V	152_Y	1.623	1.00
272_Y	283_V	1.622	1.00
38_A	321_M	1.617	1.00
487_S	494_I	1.615	1.00
37_F	41_T	1.587	1.00
220_V	223_A	1.585	1.00
309_D	313_D	1.585	1.00
25_S	331_L	1.573	1.00
17_A	22_F	1.568	1.00
255_Y	259_R	1.566	1.00
78_L	148_I	1.542	1.00
507_V	540_L	1.541	1.00
388_I	466_A	1.513	1.00
112_V	115_S	1.500	1.00
18_L	319_M	1.498	1.00
446_G	506_A	1.490	1.00
392_S	464_D	1.479	1.00
454_I	461_L	1.477	1.00
357_T	361_L	1.474	1.00
466_A	527_L	1.469	1.00
224_V	228_D	1.466	1.00
315_K	318_Y	1.460	1.00
247_E	252_S	1.446	1.00
486_I	498_L	1.442	1.00
78_L	142_I	1.440	1.00
393_R	437_K	1.432	1.00
274_G	282_L	1.431	1.00
403_Y	406_M	1.431	1.00
271_N	275_S	1.425	1.00
10_I	14_I	1.419	1.00
483_V	499_I	1.418	1.00
427_E	431_S	1.417	1.00
104_I	111_T	1.413	1.00
467_M	524_I	1.411	1.00
86_V	134_P	1.393	1.00
97_I	100_N	1.390	1.00
50_A	170_D	1.388	1.00
274_G	278_R	1.364	1.00
470_I	503_A	1.360	1.00
279_F	282_L	1.358	1.00
53_V	59_F	1.357	1.00
14_I	41_T	1.356	1.00
287_G	291_F	1.350	1.00
428_E	431_S	1.344	1.00
237_K	242_L	1.340	1.00
434_K	461_L	1.339	1.00
173_V	318_Y	1.337	1.00
49_V	174_I	1.334	1.00
403_Y	407_R	1.333	1.00
286_E	290_V	1.333	1.00
463_S	521_N	1.328	1.00
274_G	281_D	1.326	1.00
140_E	143_K	1.321	1.00
275_S	279_F	1.318	1.00
50_A	173_V	1.315	1.00
245_N	252_S	1.310	1.00
262_M	268_V	1.310	1.00
284_N	288_I	1.309	1.00
216_L	224_V	1.305	1.00
429_I	440_I	1.302	1.00
238_L	241_I	1.300	1.00
245_N	249_E	1.295	1.00
74_K	146_D	1.294	1.00
107_A	111_T	1.292	1.00
328_L	343_Y	1.291	1.00
14_I	319_M	1.288	1.00
406_M	420_E	1.285	1.00
278_R	283_V	1.282	1.00
209_V	213_L	1.273	1.00
378_A	382_A	1.271	1.00
386_L	416_R	1.269	1.00
73_K	147_V	1.265	1.00
398_A	439_I	1.262	1.00
51_F	62_V	1.262	1.00
308_T	312_N	1.261	1.00
284_N	287_G	1.260	1.00
95_Q	99_C	1.257	1.00
465_V	514_A	1.253	1.00
277_L	281_D	1.253	1.00
272_Y	280_F	1.248	1.00
276_I	281_D	1.245	1.00
13_K	342_L	1.239	1.00
56_H	59_F	1.239	1.00
436_E	457_N	1.237	1.00
173_V	315_K	1.227	1.00
222_K	225_Y	1.227	1.00
182_E	334_I	1.223	1.00
511_I	526_L	1.220	1.00
320_L	331_L	1.212	1.00
286_E	289_R	1.211	1.00
77_F	149_L	1.210	1.00
9_K	12_E	1.205	1.00
410_S	414_N	1.201	1.00
379_R	383_S	1.199	1.00
25_S	335_I	1.199	1.00
87_F	90_S	1.193	1.00
155_L	173_V	1.192	1.00
432_N	435_K	1.184	1.00
56_H	83_S	1.174	1.00
298_I	478_Y	1.169	0.99
271_N	280_F	1.169	0.99
496_N	500_S	1.162	0.99
25_S	325_M	1.162	0.99
47_P	171_Y	1.160	0.99
4_R	7_Q	1.160	0.99
43_L	73_K	1.159	0.99
472_Y	500_S	1.158	0.99
307_F	312_N	1.152	0.99
21_N	316_I	1.152	0.99
35_T	175_V	1.150	0.99
27_Q	345_D	1.147	0.99
419_A	422_T	1.147	0.99
472_Y	536_W	1.146	0.99
513_R	516_R	1.135	0.99
274_G	277_L	1.135	0.99
276_I	282_L	1.134	0.99
285_D	288_I	1.130	0.99
259_R	262_M	1.127	0.99
183_N	502_Q	1.126	0.99
196_I	275_S	1.125	0.99
407_R	411_K	1.124	0.99
262_M	269_S	1.119	0.99
24_V	319_M	1.116	0.99
63_Y	149_L	1.107	0.99
209_V	219_N	1.106	0.99
230_Y	233_I	1.106	0.99
271_N	279_F	1.101	0.99
512_G	516_R	1.101	0.99
65_E	68_L	1.099	0.99
270_R	279_F	1.098	0.99
378_A	409_V	1.097	0.99
538_K	542_C	1.096	0.99
401_P	469_G	1.095	0.99
220_V	234_E	1.093	0.99
383_S	387_K	1.093	0.99
223_A	231_I	1.088	0.99
414_N	423_E	1.084	0.99
386_L	390_Y	1.083	0.99
213_L	220_V	1.081	0.99
66_L	147_V	1.080	0.99
443_I	446_G	1.074	0.99
399_I	449_A	1.073	0.99
213_L	226_S	1.070	0.99
270_R	276_I	1.068	0.99
534_L	537_K	1.067	0.99
219_N	223_A	1.066	0.99
428_E	432_N	1.066	0.99
247_E	250_I	1.064	0.99
15_V	19_R	1.063	0.99
419_A	438_T	1.063	0.99
208_N	212_I	1.061	0.99
426_I	448_L	1.061	0.99
248_I	259_R	1.058	0.99
213_L	227_E	1.058	0.99
308_T	311_L	1.057	0.99
172_V	317_T	1.053	0.99
156_F	184_V	1.049	0.99
23_L	317_T	1.039	0.99
258_I	262_M	1.038	0.99
292_S	296_S	1.037	0.99
387_K	390_Y	1.037	0.99
277_L	282_L	1.036	0.99
274_G	280_F	1.035	0.99
272_Y	282_L	1.034	0.99
224_V	231_I	1.029	0.99
55_T	61_P	1.028	0.99
218_E	222_K	1.027	0.99
271_N	274_G	1.019	0.99
13_K	16_E	1.011	0.98
256_D	260_K	1.011	0.98
390_Y	416_R	1.010	0.98
239_D	242_L	1.002	0.98
52_V	155_L	1.002	0.98
219_N	224_V	1.001	0.98
119_S	122_K	0.997	0.98
462_I	514_A	0.995	0.98
467_M	511_I	0.993	0.98
214_E	217_K	0.988	0.98
241_I	245_N	0.988	0.98
59_F	151_T	0.987	0.98
6_W	347_E	0.986	0.98
333_N	491_K	0.986	0.98
13_K	24_V	0.980	0.98
418_L	421_D	0.978	0.98
365_D	384_Y	0.975	0.98
185_S	482_R	0.973	0.98
426_I	447_K	0.968	0.98
408_I	411_K	0.968	0.98
251_L	254_E	0.967	0.98
66_L	149_L	0.966	0.98
483_V	487_S	0.962	0.98
156_F	181_I	0.960	0.98
244_S	248_I	0.959	0.98
58_E	61_P	0.957	0.98
209_V	230_Y	0.955	0.98
409_V	412_F	0.953	0.98
35_T	39_L	0.952	0.98
272_Y	276_I	0.952	0.98
209_V	215_R	0.952	0.98
236_D	239_D	0.951	0.98
381_Y	385_L	0.946	0.98
115_S	122_K	0.944	0.98
87_F	123_L	0.944	0.98
254_E	259_R	0.943	0.98
236_D	240_N	0.940	0.98
31_G	34_K	0.938	0.98
479_L	498_L	0.938	0.98
175_V	320_L	0.937	0.98
263_I	269_S	0.936	0.98
103_E	107_A	0.936	0.98
466_A	525_W	0.934	0.97
210_K	215_R	0.933	0.97
217_K	224_V	0.933	0.97
308_T	313_D	0.933	0.97
409_V	441_M	0.932	0.97
387_K	391_N	0.931	0.97
424_T	432_N	0.929	0.97
115_S	118_V	0.927	0.97
273_L	283_V	0.926	0.97
85_C	127_G	0.923	0.97
464_D	523_T	0.922	0.97
117_K	121_N	0.922	0.97
381_Y	468_V	0.921	0.97
105_F	108_S	0.919	0.97
103_E	106_N	0.918	0.97
224_V	234_E	0.916	0.97
241_I	248_I	0.916	0.97
217_K	225_Y	0.916	0.97
271_N	282_L	0.915	0.97
277_L	280_F	0.914	0.97
23_L	26_L	0.911	0.97
273_L	282_L	0.910	0.97
55_T	65_E	0.906	0.97
276_I	283_V	0.897	0.97
223_A	232_L	0.896	0.97
285_D	289_R	0.893	0.97
271_N	281_D	0.893	0.97
259_R	264_K	0.891	0.97
349_V	456_E	0.891	0.97
4_R	28_A	0.890	0.97
224_V	227_E	0.890	0.97
381_Y	527_L	0.889	0.97
358_Y	524_I	0.887	0.97
63_Y	75_Y	0.887	0.97
237_K	241_I	0.886	0.97
259_R	268_V	0.885	0.97
249_E	252_S	0.885	0.97
221_E	228_D	0.883	0.96
68_L	71_K	0.879	0.96
86_V	90_S	0.879	0.96
209_V	220_V	0.873	0.96
127_G	133_C	0.871	0.96
271_N	276_I	0.871	0.96
240_N	243_P	0.867	0.96
217_K	227_E	0.865	0.96
244_S	252_S	0.864	0.96
509_Q	512_G	0.863	0.96
216_L	219_N	0.861	0.96
264_K	268_V	0.861	0.96
382_A	413_L	0.861	0.96
404_E	407_R	0.859	0.96
243_P	247_E	0.859	0.96
398_A	441_M	0.858	0.96
275_S	278_R	0.857	0.96
183_N	186_N	0.856	0.96
247_E	255_Y	0.856	0.96
357_T	362_I	0.856	0.96
272_Y	278_R	0.856	0.96
252_S	259_R	0.856	0.96
26_L	346_A	0.854	0.96
90_S	129_K	0.850	0.96
405_F	468_V	0.849	0.96
105_F	111_T	0.845	0.95
53_V	151_T	0.844	0.95
280_F	283_V	0.844	0.95
479_L	499_I	0.843	0.95
214_E	219_N	0.842	0.95
505_I	508_K	0.841	0.95
253_E	256_D	0.840	0.95
250_I	254_E	0.839	0.95
534_L	538_K	0.836	0.95
244_S	251_L	0.836	0.95
209_V	214_E	0.835	0.95
182_E	331_L	0.832	0.95
228_D	232_L	0.832	0.95
185_S	189_E	0.832	0.95
113_T	116_P	0.831	0.95
87_F	91_D	0.831	0.95
198_E	217_K	0.830	0.95
55_T	58_E	0.830	0.95
194_K	198_E	0.826	0.95
357_T	360_C	0.826	0.95
225_Y	228_D	0.826	0.95
261_I	265_N	0.824	0.95
244_S	247_E	0.824	0.95
369_T	529_K	0.823	0.95
265_N	268_V	0.822	0.95
328_L	336_G	0.822	0.95
210_K	218_E	0.822	0.95
361_L	525_W	0.822	0.95
29_P	346_A	0.821	0.95
74_K	141_T	0.819	0.95
397_L	510_S	0.817	0.95
54_R	180_N	0.815	0.94
410_S	420_E	0.814	0.94
377_M	381_Y	0.811	0.94
323_G	350_M	0.809	0.94
274_G	283_V	0.806	0.94
193_N	196_I	0.802	0.94
270_R	282_L	0.802	0.94
462_I	522_A	0.801	0.94
213_L	224_V	0.800	0.94
215_R	219_N	0.797	0.94
62_V	149_L	0.797	0.94
57_N	447_K	0.796	0.94
223_A	226_S	0.795	0.94
334_I	482_R	0.791	0.94
284_N	290_V	0.791	0.94
212_I	225_Y	0.791	0.94
358_Y	361_L	0.791	0.94
475_I	495_S	0.789	0.93
218_E	223_A	0.789	0.93
260_K	263_I	0.789	0.93
367_T	380_K	0.787	0.93
467_M	507_V	0.786	0.93
78_L	150_L	0.786	0.93
227_E	230_Y	0.784	0.93
213_L	217_K	0.784	0.93
150_L	155_L	0.783	0.93
449_A	508_K	0.783	0.93
12_E	16_E	0.782	0.93
259_R	269_S	0.781	0.93
410_S	441_M	0.776	0.93
408_I	412_F	0.775	0.93
328_L	331_L	0.774	0.93
360_C	363_S	0.772	0.93
504_L	543_L	0.771	0.93
245_N	250_I	0.770	0.93
235_K	242_L	0.770	0.93
248_I	252_S	0.769	0.93
150_L	154_Y	0.768	0.93
89_S	105_F	0.768	0.93
80_G	83_S	0.767	0.93
270_R	283_V	0.767	0.93
57_N	61_P	0.766	0.92
225_Y	231_I	0.765	0.92
38_A	51_F	0.765	0.92
397_L	465_V	0.765	0.92
248_I	266_K	0.764	0.92
456_E	462_I	0.764	0.92
228_D	233_I	0.763	0.92
224_V	233_I	0.762	0.92
285_D	290_V	0.761	0.92
301_Y	304_P	0.761	0.92
227_E	234_E	0.760	0.92
265_N	269_S	0.759	0.92
30_T	302_I	0.759	0.92
18_L	317_T	0.757	0.92
278_R	281_D	0.755	0.92
395_H	436_E	0.755	0.92
219_N	222_K	0.754	0.92
262_M	267_T	0.754	0.92
27_Q	32_S	0.751	0.92
264_K	269_S	0.750	0.92
235_K	245_N	0.750	0.92
259_R	265_N	0.749	0.92
260_K	265_N	0.748	0.92
246_E	253_E	0.747	0.91
212_I	219_N	0.746	0.91
18_L	42_A	0.746	0.91
371_S	376_Q	0.743	0.91
395_H	464_D	0.742	0.91
249_E	253_E	0.741	0.91
481_I	484_E	0.740	0.91
378_A	405_F	0.740	0.91
239_D	243_P	0.739	0.91
418_L	422_T	0.739	0.91
257_E	263_I	0.738	0.91
366_V	384_Y	0.738	0.91
357_T	363_S	0.737	0.91
220_V	224_V	0.737	0.91
224_V	230_Y	0.734	0.91
263_I	267_T	0.733	0.91
78_L	138_L	0.733	0.91
244_S	258_I	0.733	0.91
509_Q	516_R	0.732	0.91
48_K	145_A	0.731	0.91
443_I	449_A	0.731	0.91
258_I	269_S	0.731	0.91
220_V	225_Y	0.730	0.91
390_Y	415_I	0.730	0.91
250_I	253_E	0.729	0.90
394_R	463_S	0.728	0.90
210_K	231_I	0.727	0.90
209_V	234_E	0.726	0.90
214_E	218_E	0.725	0.90
17_A	23_L	0.724	0.90
246_E	250_I	0.724	0.90
252_S	265_N	0.724	0.90
380_K	383_S	0.723	0.90
416_R	437_K	0.722	0.90
13_K	346_A	0.722	0.90
88_S	91_D	0.722	0.90
79_V	84_A	0.721	0.90
392_S	463_S	0.719	0.90
397_L	442_G	0.718	0.90
264_K	267_T	0.718	0.90
237_K	243_P	0.716	0.90
215_R	222_K	0.713	0.90
215_R	223_A	0.711	0.89
217_K	222_K	0.708	0.89
262_M	266_K	0.708	0.89
430_M	454_I	0.707	0.89
54_R	58_E	0.704	0.89
452_I	515_I	0.704	0.89
424_T	428_E	0.704	0.89
473_P	502_Q	0.702	0.89
531_Y	541_N	0.701	0.89
254_E	262_M	0.701	0.89
498_L	502_Q	0.699	0.89
179_H	322_S	0.699	0.89
241_I	259_R	0.699	0.89
252_S	257_E	0.696	0.88
248_I	262_M	0.695	0.88
257_E	267_T	0.694	0.88
208_N	211_V	0.692	0.88
237_K	240_N	0.690	0.88
473_P	483_V	0.689	0.88
509_Q	513_R	0.689	0.88
81_K	158_P	0.689	0.88
258_I	261_I	0.688	0.88
476_D	479_L	0.686	0.88
209_V	224_V	0.686	0.88
367_T	529_K	0.685	0.88
365_D	529_K	0.683	0.87
153_P	187_I	0.683	0.87
55_T	59_F	0.683	0.87
11_A	41_T	0.682	0.87
76_G	138_L	0.682	0.87
3_L	8_S	0.682	0.87
165_D	168_W	0.681	0.87
360_C	526_L	0.680	0.87
286_E	291_F	0.680	0.87
306_Y	309_D	0.680	0.87
253_E	257_E	0.680	0.87
273_L	281_D	0.678	0.87
225_Y	229_K	0.678	0.87
261_I	264_K	0.677	0.87
257_E	261_I	0.675	0.87
186_N	189_E	0.675	0.87
480_K	483_V	0.674	0.87
242_L	245_N	0.673	0.87
480_K	484_E	0.672	0.87
235_K	259_R	0.671	0.86
81_K	85_C	0.671	0.86
60_F	427_E	0.668	0.86
118_V	121_N	0.666	0.86
247_E	256_D	0.661	0.86
235_K	249_E	0.660	0.86
397_L	454_I	0.658	0.85
270_R	275_S	0.657	0.85
240_N	247_E	0.656	0.85
504_L	507_V	0.655	0.85
483_V	496_N	0.654	0.85
215_R	221_E	0.653	0.85
209_V	217_K	0.653	0.85
11_A	15_V	0.651	0.85
417_Y	422_T	0.650	0.85
211_V	214_E	0.650	0.85
270_R	281_D	0.649	0.85
10_I	346_A	0.648	0.85
322_S	453_E	0.648	0.85
79_V	151_T	0.647	0.84
362_I	532_D	0.647	0.84
253_E	259_R	0.646	0.84
29_P	349_V	0.645	0.84
6_W	32_S	0.643	0.84
55_T	81_K	0.642	0.84
256_D	261_I	0.640	0.84
219_N	228_D	0.639	0.84
210_K	214_E	0.638	0.84
227_E	233_I	0.637	0.84
254_E	257_E	0.636	0.83
235_K	261_I	0.635	0.83
79_V	83_S	0.635	0.83
456_E	517_G	0.634	0.83
378_A	381_Y	0.633	0.83
177_E	513_R	0.633	0.83
228_D	231_I	0.628	0.83
244_S	249_E	0.628	0.83
210_K	216_L	0.628	0.83
358_Y	363_S	0.627	0.83
357_T	515_I	0.626	0.82
117_K	123_L	0.626	0.82
324_T	516_R	0.625	0.82
216_L	223_A	0.625	0.82
276_I	280_F	0.624	0.82
209_V	222_K	0.624	0.82
5_E	8_S	0.623	0.82
388_I	527_L	0.622	0.82
43_L	147_V	0.621	0.82
124_K	128_K	0.621	0.82
401_P	449_A	0.620	0.82
526_L	544_N	0.620	0.82
78_L	154_Y	0.620	0.82
9_K	344_I	0.619	0.82
426_I	430_M	0.618	0.82
259_R	263_I	0.617	0.82
29_P	348_K	0.616	0.81
154_Y	157_I	0.615	0.81
17_A	319_M	0.614	0.81
80_G	151_T	0.613	0.81
226_S	230_Y	0.613	0.81
453_E	522_A	0.613	0.81
220_V	226_S	0.611	0.81
156_F	299_A	0.611	0.81
504_L	539_E	0.609	0.81
529_K	533_S	0.608	0.81
81_K	135_Y	0.608	0.81
479_L	483_V	0.607	0.81
95_Q	100_N	0.607	0.81
76_G	142_I	0.606	0.80
242_L	246_E	0.605	0.80
39_L	43_L	0.605	0.80
220_V	227_E	0.604	0.80
177_E	516_R	0.602	0.80
328_L	332_R	0.601	0.80
39_L	62_V	0.601	0.80
238_L	242_L	0.601	0.80
277_L	283_V	0.601	0.80
214_E	220_V	0.601	0.80
214_E	225_Y	0.599	0.80
235_K	241_I	0.596	0.79
4_R	11_A	0.595	0.79
61_P	65_E	0.595	0.79
359_E	523_T	0.594	0.79
46_K	49_V	0.594	0.79
398_A	466_A	0.594	0.79
216_L	220_V	0.594	0.79
246_E	254_E	0.594	0.79
177_E	512_G	0.594	0.79
112_V	118_V	0.592	0.79
262_M	265_N	0.592	0.79
302_I	482_R	0.591	0.79
500_S	535_W	0.591	0.79
271_N	278_R	0.590	0.79
273_L	280_F	0.590	0.79
220_V	233_I	0.589	0.79
507_V	531_Y	0.588	0.78
192_L	297_L	0.588	0.78
505_I	515_I	0.587	0.78
388_I	523_T	0.586	0.78
242_L	249_E	0.586	0.78
208_N	220_V	0.584	0.78
245_N	254_E	0.582	0.78
372_L	377_M	0.581	0.78
84_A	124_K	0.580	0.77
451_G	516_R	0.579	0.77
164_L	167_N	0.579	0.77
236_D	242_L	0.579	0.77
254_E	260_K	0.579	0.77
213_L	233_I	0.578	0.77
28_A	32_S	0.577	0.77
537_K	545_A	0.577	0.77
52_V	175_V	0.577	0.77
246_E	257_E	0.575	0.77
312_N	318_Y	0.575	0.77
38_A	152_Y	0.574	0.77
115_S	126_E	0.573	0.77
54_R	57_N	0.573	0.77
451_G	512_G	0.573	0.77
154_Y	158_P	0.573	0.77
307_F	310_I	0.571	0.76
210_K	220_V	0.571	0.76
287_G	299_A	0.570	0.76
226_S	231_I	0.569	0.76
209_V	221_E	0.567	0.76
266_K	272_Y	0.566	0.76
238_L	243_P	0.566	0.76
18_L	316_I	0.566	0.76
239_D	254_E	0.566	0.76
30_T	503_A	0.565	0.76
210_K	213_L	0.565	0.76
246_E	260_K	0.565	0.76
58_E	151_T	0.564	0.75
29_P	51_F	0.564	0.75
247_E	254_E	0.563	0.75
236_D	241_I	0.562	0.75
433_L	462_I	0.562	0.75
427_E	457_N	0.562	0.75
32_S	328_L	0.561	0.75
324_T	512_G	0.561	0.75
391_N	521_N	0.561	0.75
240_N	245_N	0.561	0.75
26_L	344_I	0.560	0.75
332_R	341_I	0.557	0.75
304_P	327_P	0.557	0.75
98_Y	101_G	0.556	0.74
152_Y	158_P	0.555	0.74
236_D	245_N	0.555	0.74
378_A	408_I	0.554	0.74
40_Y	69_H	0.553	0.74
25_S	337_I	0.552	0.74
288_I	481_I	0.552	0.74
16_E	342_L	0.552	0.74
70_F	73_K	0.552	0.74
245_N	248_I	0.551	0.74
227_E	231_I	0.551	0.74
247_E	251_L	0.551	0.74
433_L	438_T	0.550	0.74
156_F	312_N	0.550	0.74
322_S	397_L	0.550	0.74
346_A	455_V	0.550	0.74
210_K	217_K	0.548	0.73
366_V	380_K	0.548	0.73
268_V	272_Y	0.547	0.73
366_V	369_T	0.545	0.73
433_L	461_L	0.544	0.73
43_L	66_L	0.544	0.73
219_N	227_E	0.542	0.73
32_S	348_K	0.541	0.72
75_Y	147_V	0.540	0.72
245_N	259_R	0.538	0.72
386_L	413_L	0.538	0.72
236_D	250_I	0.538	0.72
51_F	147_V	0.538	0.72
330_Y	334_I	0.537	0.72
211_V	225_Y	0.537	0.72
255_Y	258_I	0.536	0.72
515_I	520_D	0.536	0.72
48_K	171_Y	0.535	0.72
310_I	313_D	0.534	0.72
6_W	181_I	0.534	0.72
118_V	122_K	0.533	0.71
182_E	185_S	0.533	0.71
243_P	248_I	0.531	0.71
253_E	263_I	0.531	0.71
36_L	40_Y	0.530	0.71
495_S	500_S	0.529	0.71
352_K	545_A	0.529	0.71
322_S	325_M	0.529	0.71
357_T	384_Y	0.528	0.71
14_I	26_L	0.528	0.71
158_P	168_W	0.528	0.71
106_N	109_A	0.527	0.71
272_Y	277_L	0.527	0.71
411_K	414_N	0.526	0.70
212_I	227_E	0.525	0.70
56_H	151_T	0.525	0.70
141_T	145_A	0.523	0.70
216_L	227_E	0.523	0.70
330_Y	426_I	0.522	0.70
185_S	300_K	0.521	0.70
104_I	107_A	0.520	0.70
360_C	531_Y	0.520	0.70
36_L	69_H	0.520	0.70
93_D	102_C	0.520	0.70
177_E	509_Q	0.519	0.69
229_K	233_I	0.519	0.69
362_I	365_D	0.519	0.69
247_E	259_R	0.518	0.69
235_K	247_E	0.518	0.69
18_L	45_V	0.518	0.69
451_G	513_R	0.518	0.69
212_I	223_A	0.518	0.69
188_E	307_F	0.517	0.69
152_Y	399_I	0.517	0.69
56_H	61_P	0.516	0.69
116_P	122_K	0.516	0.69
218_E	228_D	0.516	0.69
241_I	249_E	0.516	0.69
218_E	221_E	0.516	0.69
14_I	38_A	0.516	0.69
38_A	62_V	0.515	0.69
177_E	324_T	0.515	0.69
239_D	247_E	0.514	0.69
472_Y	495_S	0.514	0.69
369_T	372_L	0.514	0.69
275_S	281_D	0.513	0.68
361_L	365_D	0.513	0.68
59_F	507_V	0.512	0.68
225_Y	230_Y	0.512	0.68
35_T	450_E	0.512	0.68
27_Q	326_Q	0.512	0.68
244_S	262_M	0.512	0.68
407_R	422_T	0.512	0.68
15_V	44_K	0.510	0.68
28_A	151_T	0.508	0.68
243_P	246_E	0.507	0.68
411_K	415_I	0.507	0.68
236_D	251_L	0.507	0.68
52_V	452_I	0.507	0.68
86_V	132_F	0.506	0.67
396_V	430_M	0.506	0.67
158_P	161_R	0.505	0.67
241_I	247_E	0.504	0.67
394_R	433_L	0.504	0.67
261_I	266_K	0.504	0.67
9_K	346_A	0.504	0.67
364_I	532_D	0.503	0.67
221_E	226_S	0.502	0.67
217_K	231_I	0.501	0.67
64_R	76_G	0.501	0.67
62_V	65_E	0.500	0.67
263_I	268_V	0.500	0.67

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3crvA	1	0.9818	100	0.271	Contact Map
4a15A	1	0.9382	100	0.278	Contact Map
2vl7A	1	0.8036	100	0.329	Contact Map
1gkuB	1	0.6364	100	0.736	Contact Map
4ys0A	1	0.8636	100	0.754	Contact Map
4dduA	1	0.6673	100	0.764	Contact Map
3fhoA	2	0.5309	100	0.767	Contact Map
4w7sA	2	0.6145	100	0.776	Contact Map
4bgdA	1	0.6364	100	0.777	Contact Map
4q2cA	1	0.6891	100	0.78	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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