GREMLIN Database
Q980I2 - DNA helicase
UniProt: Q980I2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 550 (528)
Sequences: 4204 (3193)
Seq/√Len: 139.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
351_K354_L6.4271.00
379_R412_F4.5061.00
400_F409_V4.2981.00
178_A320_L4.1671.00
42_A174_I4.0081.00
413_L441_M3.9521.00
385_L466_A3.9161.00
155_L175_V3.6691.00
389_F396_V3.6231.00
400_F441_M3.2761.00
5_E9_K3.2741.00
18_L172_V3.2711.00
10_I26_L3.2551.00
85_C133_C3.1331.00
392_S396_V3.1001.00
486_I491_K3.0081.00
108_S111_T2.9131.00
332_R343_Y2.8981.00
388_I525_W2.8071.00
514_A522_A2.7761.00
395_H463_S2.7461.00
66_L75_Y2.6901.00
17_A24_V2.6261.00
403_Y443_I2.5441.00
385_L398_A2.4861.00
272_Y275_S2.4861.00
42_A49_V2.3821.00
13_K344_I2.3481.00
273_L279_F2.3061.00
382_A412_F2.2791.00
76_G145_A2.2681.00
449_A510_S2.2601.00
104_I108_S2.2581.00
270_R274_G2.2511.00
279_F283_V2.2181.00
10_I321_M2.1991.00
404_E408_I2.1861.00
526_L531_Y2.1611.00
511_I524_I2.1571.00
175_V181_I2.1491.00
431_S435_K2.1041.00
287_G290_V2.0701.00
455_V517_G2.0561.00
384_Y527_L2.0551.00
35_T62_V2.0401.00
16_E20_N2.0371.00
464_D525_W2.0251.00
6_W346_A2.0221.00
221_E224_V2.0151.00
274_G279_F1.9981.00
22_F342_L1.9881.00
272_Y279_F1.9871.00
389_F439_I1.9521.00
388_I464_D1.9421.00
209_V212_I1.9061.00
396_V464_D1.8891.00
394_R457_N1.8851.00
417_Y420_E1.8791.00
217_K221_E1.8651.00
266_K269_S1.8631.00
180_N450_E1.8561.00
457_N463_S1.8441.00
8_S12_E1.8431.00
331_L335_I1.8411.00
491_K497_E1.8221.00
191_K298_I1.8181.00
504_L540_L1.8011.00
507_V526_L1.7981.00
276_I279_F1.7851.00
312_N320_L1.7761.00
400_F406_M1.7691.00
221_E225_Y1.7581.00
417_Y421_D1.7541.00
122_K127_G1.7481.00
484_E487_S1.7251.00
485_E489_I1.7161.00
25_S332_R1.7161.00
63_Y77_F1.7081.00
382_A409_V1.7001.00
288_I291_F1.6741.00
484_E488_K1.6621.00
406_M441_M1.6541.00
270_R273_L1.6341.00
273_L276_I1.6341.00
326_Q345_D1.6321.00
17_A317_T1.6261.00
496_N535_W1.6241.00
52_V152_Y1.6231.00
272_Y283_V1.6221.00
38_A321_M1.6171.00
487_S494_I1.6151.00
37_F41_T1.5871.00
220_V223_A1.5851.00
309_D313_D1.5851.00
25_S331_L1.5731.00
17_A22_F1.5681.00
255_Y259_R1.5661.00
78_L148_I1.5421.00
507_V540_L1.5411.00
388_I466_A1.5131.00
112_V115_S1.5001.00
18_L319_M1.4981.00
446_G506_A1.4901.00
392_S464_D1.4791.00
454_I461_L1.4771.00
357_T361_L1.4741.00
466_A527_L1.4691.00
224_V228_D1.4661.00
315_K318_Y1.4601.00
247_E252_S1.4461.00
486_I498_L1.4421.00
78_L142_I1.4401.00
393_R437_K1.4321.00
274_G282_L1.4311.00
403_Y406_M1.4311.00
271_N275_S1.4251.00
10_I14_I1.4191.00
483_V499_I1.4181.00
427_E431_S1.4171.00
104_I111_T1.4131.00
467_M524_I1.4111.00
86_V134_P1.3931.00
97_I100_N1.3901.00
50_A170_D1.3881.00
274_G278_R1.3641.00
470_I503_A1.3601.00
279_F282_L1.3581.00
53_V59_F1.3571.00
14_I41_T1.3561.00
287_G291_F1.3501.00
428_E431_S1.3441.00
237_K242_L1.3401.00
434_K461_L1.3391.00
173_V318_Y1.3371.00
49_V174_I1.3341.00
403_Y407_R1.3331.00
286_E290_V1.3331.00
463_S521_N1.3281.00
274_G281_D1.3261.00
140_E143_K1.3211.00
275_S279_F1.3181.00
50_A173_V1.3151.00
245_N252_S1.3101.00
262_M268_V1.3101.00
284_N288_I1.3091.00
216_L224_V1.3051.00
429_I440_I1.3021.00
238_L241_I1.3001.00
245_N249_E1.2951.00
74_K146_D1.2941.00
107_A111_T1.2921.00
328_L343_Y1.2911.00
14_I319_M1.2881.00
406_M420_E1.2851.00
278_R283_V1.2821.00
209_V213_L1.2731.00
378_A382_A1.2711.00
386_L416_R1.2691.00
73_K147_V1.2651.00
398_A439_I1.2621.00
51_F62_V1.2621.00
308_T312_N1.2611.00
284_N287_G1.2601.00
95_Q99_C1.2571.00
465_V514_A1.2531.00
277_L281_D1.2531.00
272_Y280_F1.2481.00
276_I281_D1.2451.00
13_K342_L1.2391.00
56_H59_F1.2391.00
436_E457_N1.2371.00
173_V315_K1.2271.00
222_K225_Y1.2271.00
182_E334_I1.2231.00
511_I526_L1.2201.00
320_L331_L1.2121.00
286_E289_R1.2111.00
77_F149_L1.2101.00
9_K12_E1.2051.00
410_S414_N1.2011.00
379_R383_S1.1991.00
25_S335_I1.1991.00
87_F90_S1.1931.00
155_L173_V1.1921.00
432_N435_K1.1841.00
56_H83_S1.1741.00
298_I478_Y1.1690.99
271_N280_F1.1690.99
496_N500_S1.1620.99
25_S325_M1.1620.99
47_P171_Y1.1600.99
4_R7_Q1.1600.99
43_L73_K1.1590.99
472_Y500_S1.1580.99
307_F312_N1.1520.99
21_N316_I1.1520.99
35_T175_V1.1500.99
27_Q345_D1.1470.99
419_A422_T1.1470.99
472_Y536_W1.1460.99
513_R516_R1.1350.99
274_G277_L1.1350.99
276_I282_L1.1340.99
285_D288_I1.1300.99
259_R262_M1.1270.99
183_N502_Q1.1260.99
196_I275_S1.1250.99
407_R411_K1.1240.99
262_M269_S1.1190.99
24_V319_M1.1160.99
63_Y149_L1.1070.99
209_V219_N1.1060.99
230_Y233_I1.1060.99
271_N279_F1.1010.99
512_G516_R1.1010.99
65_E68_L1.0990.99
270_R279_F1.0980.99
378_A409_V1.0970.99
538_K542_C1.0960.99
401_P469_G1.0950.99
220_V234_E1.0930.99
383_S387_K1.0930.99
223_A231_I1.0880.99
414_N423_E1.0840.99
386_L390_Y1.0830.99
213_L220_V1.0810.99
66_L147_V1.0800.99
443_I446_G1.0740.99
399_I449_A1.0730.99
213_L226_S1.0700.99
270_R276_I1.0680.99
534_L537_K1.0670.99
219_N223_A1.0660.99
428_E432_N1.0660.99
247_E250_I1.0640.99
15_V19_R1.0630.99
419_A438_T1.0630.99
208_N212_I1.0610.99
426_I448_L1.0610.99
248_I259_R1.0580.99
213_L227_E1.0580.99
308_T311_L1.0570.99
172_V317_T1.0530.99
156_F184_V1.0490.99
23_L317_T1.0390.99
258_I262_M1.0380.99
292_S296_S1.0370.99
387_K390_Y1.0370.99
277_L282_L1.0360.99
274_G280_F1.0350.99
272_Y282_L1.0340.99
224_V231_I1.0290.99
55_T61_P1.0280.99
218_E222_K1.0270.99
271_N274_G1.0190.99
13_K16_E1.0110.98
256_D260_K1.0110.98
390_Y416_R1.0100.98
239_D242_L1.0020.98
52_V155_L1.0020.98
219_N224_V1.0010.98
119_S122_K0.9970.98
462_I514_A0.9950.98
467_M511_I0.9930.98
214_E217_K0.9880.98
241_I245_N0.9880.98
59_F151_T0.9870.98
6_W347_E0.9860.98
333_N491_K0.9860.98
13_K24_V0.9800.98
418_L421_D0.9780.98
365_D384_Y0.9750.98
185_S482_R0.9730.98
426_I447_K0.9680.98
408_I411_K0.9680.98
251_L254_E0.9670.98
66_L149_L0.9660.98
483_V487_S0.9620.98
156_F181_I0.9600.98
244_S248_I0.9590.98
58_E61_P0.9570.98
209_V230_Y0.9550.98
409_V412_F0.9530.98
35_T39_L0.9520.98
272_Y276_I0.9520.98
209_V215_R0.9520.98
236_D239_D0.9510.98
381_Y385_L0.9460.98
115_S122_K0.9440.98
87_F123_L0.9440.98
254_E259_R0.9430.98
236_D240_N0.9400.98
31_G34_K0.9380.98
479_L498_L0.9380.98
175_V320_L0.9370.98
263_I269_S0.9360.98
103_E107_A0.9360.98
466_A525_W0.9340.97
210_K215_R0.9330.97
217_K224_V0.9330.97
308_T313_D0.9330.97
409_V441_M0.9320.97
387_K391_N0.9310.97
424_T432_N0.9290.97
115_S118_V0.9270.97
273_L283_V0.9260.97
85_C127_G0.9230.97
464_D523_T0.9220.97
117_K121_N0.9220.97
381_Y468_V0.9210.97
105_F108_S0.9190.97
103_E106_N0.9180.97
224_V234_E0.9160.97
241_I248_I0.9160.97
217_K225_Y0.9160.97
271_N282_L0.9150.97
277_L280_F0.9140.97
23_L26_L0.9110.97
273_L282_L0.9100.97
55_T65_E0.9060.97
276_I283_V0.8970.97
223_A232_L0.8960.97
285_D289_R0.8930.97
271_N281_D0.8930.97
259_R264_K0.8910.97
349_V456_E0.8910.97
4_R28_A0.8900.97
224_V227_E0.8900.97
381_Y527_L0.8890.97
358_Y524_I0.8870.97
63_Y75_Y0.8870.97
237_K241_I0.8860.97
259_R268_V0.8850.97
249_E252_S0.8850.97
221_E228_D0.8830.96
68_L71_K0.8790.96
86_V90_S0.8790.96
209_V220_V0.8730.96
127_G133_C0.8710.96
271_N276_I0.8710.96
240_N243_P0.8670.96
217_K227_E0.8650.96
244_S252_S0.8640.96
509_Q512_G0.8630.96
216_L219_N0.8610.96
264_K268_V0.8610.96
382_A413_L0.8610.96
404_E407_R0.8590.96
243_P247_E0.8590.96
398_A441_M0.8580.96
275_S278_R0.8570.96
183_N186_N0.8560.96
247_E255_Y0.8560.96
357_T362_I0.8560.96
272_Y278_R0.8560.96
252_S259_R0.8560.96
26_L346_A0.8540.96
90_S129_K0.8500.96
405_F468_V0.8490.96
105_F111_T0.8450.95
53_V151_T0.8440.95
280_F283_V0.8440.95
479_L499_I0.8430.95
214_E219_N0.8420.95
505_I508_K0.8410.95
253_E256_D0.8400.95
250_I254_E0.8390.95
534_L538_K0.8360.95
244_S251_L0.8360.95
209_V214_E0.8350.95
182_E331_L0.8320.95
228_D232_L0.8320.95
185_S189_E0.8320.95
113_T116_P0.8310.95
87_F91_D0.8310.95
198_E217_K0.8300.95
55_T58_E0.8300.95
194_K198_E0.8260.95
357_T360_C0.8260.95
225_Y228_D0.8260.95
261_I265_N0.8240.95
244_S247_E0.8240.95
369_T529_K0.8230.95
265_N268_V0.8220.95
328_L336_G0.8220.95
210_K218_E0.8220.95
361_L525_W0.8220.95
29_P346_A0.8210.95
74_K141_T0.8190.95
397_L510_S0.8170.95
54_R180_N0.8150.94
410_S420_E0.8140.94
377_M381_Y0.8110.94
323_G350_M0.8090.94
274_G283_V0.8060.94
193_N196_I0.8020.94
270_R282_L0.8020.94
462_I522_A0.8010.94
213_L224_V0.8000.94
215_R219_N0.7970.94
62_V149_L0.7970.94
57_N447_K0.7960.94
223_A226_S0.7950.94
334_I482_R0.7910.94
284_N290_V0.7910.94
212_I225_Y0.7910.94
358_Y361_L0.7910.94
475_I495_S0.7890.93
218_E223_A0.7890.93
260_K263_I0.7890.93
367_T380_K0.7870.93
467_M507_V0.7860.93
78_L150_L0.7860.93
227_E230_Y0.7840.93
213_L217_K0.7840.93
150_L155_L0.7830.93
449_A508_K0.7830.93
12_E16_E0.7820.93
259_R269_S0.7810.93
410_S441_M0.7760.93
408_I412_F0.7750.93
328_L331_L0.7740.93
360_C363_S0.7720.93
504_L543_L0.7710.93
245_N250_I0.7700.93
235_K242_L0.7700.93
248_I252_S0.7690.93
150_L154_Y0.7680.93
89_S105_F0.7680.93
80_G83_S0.7670.93
270_R283_V0.7670.93
57_N61_P0.7660.92
225_Y231_I0.7650.92
38_A51_F0.7650.92
397_L465_V0.7650.92
248_I266_K0.7640.92
456_E462_I0.7640.92
228_D233_I0.7630.92
224_V233_I0.7620.92
285_D290_V0.7610.92
301_Y304_P0.7610.92
227_E234_E0.7600.92
265_N269_S0.7590.92
30_T302_I0.7590.92
18_L317_T0.7570.92
278_R281_D0.7550.92
395_H436_E0.7550.92
219_N222_K0.7540.92
262_M267_T0.7540.92
27_Q32_S0.7510.92
264_K269_S0.7500.92
235_K245_N0.7500.92
259_R265_N0.7490.92
260_K265_N0.7480.92
246_E253_E0.7470.91
212_I219_N0.7460.91
18_L42_A0.7460.91
371_S376_Q0.7430.91
395_H464_D0.7420.91
249_E253_E0.7410.91
481_I484_E0.7400.91
378_A405_F0.7400.91
239_D243_P0.7390.91
418_L422_T0.7390.91
257_E263_I0.7380.91
366_V384_Y0.7380.91
357_T363_S0.7370.91
220_V224_V0.7370.91
224_V230_Y0.7340.91
263_I267_T0.7330.91
78_L138_L0.7330.91
244_S258_I0.7330.91
509_Q516_R0.7320.91
48_K145_A0.7310.91
443_I449_A0.7310.91
258_I269_S0.7310.91
220_V225_Y0.7300.91
390_Y415_I0.7300.91
250_I253_E0.7290.90
394_R463_S0.7280.90
210_K231_I0.7270.90
209_V234_E0.7260.90
214_E218_E0.7250.90
17_A23_L0.7240.90
246_E250_I0.7240.90
252_S265_N0.7240.90
380_K383_S0.7230.90
416_R437_K0.7220.90
13_K346_A0.7220.90
88_S91_D0.7220.90
79_V84_A0.7210.90
392_S463_S0.7190.90
397_L442_G0.7180.90
264_K267_T0.7180.90
237_K243_P0.7160.90
215_R222_K0.7130.90
215_R223_A0.7110.89
217_K222_K0.7080.89
262_M266_K0.7080.89
430_M454_I0.7070.89
54_R58_E0.7040.89
452_I515_I0.7040.89
424_T428_E0.7040.89
473_P502_Q0.7020.89
531_Y541_N0.7010.89
254_E262_M0.7010.89
498_L502_Q0.6990.89
179_H322_S0.6990.89
241_I259_R0.6990.89
252_S257_E0.6960.88
248_I262_M0.6950.88
257_E267_T0.6940.88
208_N211_V0.6920.88
237_K240_N0.6900.88
473_P483_V0.6890.88
509_Q513_R0.6890.88
81_K158_P0.6890.88
258_I261_I0.6880.88
476_D479_L0.6860.88
209_V224_V0.6860.88
367_T529_K0.6850.88
365_D529_K0.6830.87
153_P187_I0.6830.87
55_T59_F0.6830.87
11_A41_T0.6820.87
76_G138_L0.6820.87
3_L8_S0.6820.87
165_D168_W0.6810.87
360_C526_L0.6800.87
286_E291_F0.6800.87
306_Y309_D0.6800.87
253_E257_E0.6800.87
273_L281_D0.6780.87
225_Y229_K0.6780.87
261_I264_K0.6770.87
257_E261_I0.6750.87
186_N189_E0.6750.87
480_K483_V0.6740.87
242_L245_N0.6730.87
480_K484_E0.6720.87
235_K259_R0.6710.86
81_K85_C0.6710.86
60_F427_E0.6680.86
118_V121_N0.6660.86
247_E256_D0.6610.86
235_K249_E0.6600.86
397_L454_I0.6580.85
270_R275_S0.6570.85
240_N247_E0.6560.85
504_L507_V0.6550.85
483_V496_N0.6540.85
215_R221_E0.6530.85
209_V217_K0.6530.85
11_A15_V0.6510.85
417_Y422_T0.6500.85
211_V214_E0.6500.85
270_R281_D0.6490.85
10_I346_A0.6480.85
322_S453_E0.6480.85
79_V151_T0.6470.84
362_I532_D0.6470.84
253_E259_R0.6460.84
29_P349_V0.6450.84
6_W32_S0.6430.84
55_T81_K0.6420.84
256_D261_I0.6400.84
219_N228_D0.6390.84
210_K214_E0.6380.84
227_E233_I0.6370.84
254_E257_E0.6360.83
235_K261_I0.6350.83
79_V83_S0.6350.83
456_E517_G0.6340.83
378_A381_Y0.6330.83
177_E513_R0.6330.83
228_D231_I0.6280.83
244_S249_E0.6280.83
210_K216_L0.6280.83
358_Y363_S0.6270.83
357_T515_I0.6260.82
117_K123_L0.6260.82
324_T516_R0.6250.82
216_L223_A0.6250.82
276_I280_F0.6240.82
209_V222_K0.6240.82
5_E8_S0.6230.82
388_I527_L0.6220.82
43_L147_V0.6210.82
124_K128_K0.6210.82
401_P449_A0.6200.82
526_L544_N0.6200.82
78_L154_Y0.6200.82
9_K344_I0.6190.82
426_I430_M0.6180.82
259_R263_I0.6170.82
29_P348_K0.6160.81
154_Y157_I0.6150.81
17_A319_M0.6140.81
80_G151_T0.6130.81
226_S230_Y0.6130.81
453_E522_A0.6130.81
220_V226_S0.6110.81
156_F299_A0.6110.81
504_L539_E0.6090.81
529_K533_S0.6080.81
81_K135_Y0.6080.81
479_L483_V0.6070.81
95_Q100_N0.6070.81
76_G142_I0.6060.80
242_L246_E0.6050.80
39_L43_L0.6050.80
220_V227_E0.6040.80
177_E516_R0.6020.80
328_L332_R0.6010.80
39_L62_V0.6010.80
238_L242_L0.6010.80
277_L283_V0.6010.80
214_E220_V0.6010.80
214_E225_Y0.5990.80
235_K241_I0.5960.79
4_R11_A0.5950.79
61_P65_E0.5950.79
359_E523_T0.5940.79
46_K49_V0.5940.79
398_A466_A0.5940.79
216_L220_V0.5940.79
246_E254_E0.5940.79
177_E512_G0.5940.79
112_V118_V0.5920.79
262_M265_N0.5920.79
302_I482_R0.5910.79
500_S535_W0.5910.79
271_N278_R0.5900.79
273_L280_F0.5900.79
220_V233_I0.5890.79
507_V531_Y0.5880.78
192_L297_L0.5880.78
505_I515_I0.5870.78
388_I523_T0.5860.78
242_L249_E0.5860.78
208_N220_V0.5840.78
245_N254_E0.5820.78
372_L377_M0.5810.78
84_A124_K0.5800.77
451_G516_R0.5790.77
164_L167_N0.5790.77
236_D242_L0.5790.77
254_E260_K0.5790.77
213_L233_I0.5780.77
28_A32_S0.5770.77
537_K545_A0.5770.77
52_V175_V0.5770.77
246_E257_E0.5750.77
312_N318_Y0.5750.77
38_A152_Y0.5740.77
115_S126_E0.5730.77
54_R57_N0.5730.77
451_G512_G0.5730.77
154_Y158_P0.5730.77
307_F310_I0.5710.76
210_K220_V0.5710.76
287_G299_A0.5700.76
226_S231_I0.5690.76
209_V221_E0.5670.76
266_K272_Y0.5660.76
238_L243_P0.5660.76
18_L316_I0.5660.76
239_D254_E0.5660.76
30_T503_A0.5650.76
210_K213_L0.5650.76
246_E260_K0.5650.76
58_E151_T0.5640.75
29_P51_F0.5640.75
247_E254_E0.5630.75
236_D241_I0.5620.75
433_L462_I0.5620.75
427_E457_N0.5620.75
32_S328_L0.5610.75
324_T512_G0.5610.75
391_N521_N0.5610.75
240_N245_N0.5610.75
26_L344_I0.5600.75
332_R341_I0.5570.75
304_P327_P0.5570.75
98_Y101_G0.5560.74
152_Y158_P0.5550.74
236_D245_N0.5550.74
378_A408_I0.5540.74
40_Y69_H0.5530.74
25_S337_I0.5520.74
288_I481_I0.5520.74
16_E342_L0.5520.74
70_F73_K0.5520.74
245_N248_I0.5510.74
227_E231_I0.5510.74
247_E251_L0.5510.74
433_L438_T0.5500.74
156_F312_N0.5500.74
322_S397_L0.5500.74
346_A455_V0.5500.74
210_K217_K0.5480.73
366_V380_K0.5480.73
268_V272_Y0.5470.73
366_V369_T0.5450.73
433_L461_L0.5440.73
43_L66_L0.5440.73
219_N227_E0.5420.73
32_S348_K0.5410.72
75_Y147_V0.5400.72
245_N259_R0.5380.72
386_L413_L0.5380.72
236_D250_I0.5380.72
51_F147_V0.5380.72
330_Y334_I0.5370.72
211_V225_Y0.5370.72
255_Y258_I0.5360.72
515_I520_D0.5360.72
48_K171_Y0.5350.72
310_I313_D0.5340.72
6_W181_I0.5340.72
118_V122_K0.5330.71
182_E185_S0.5330.71
243_P248_I0.5310.71
253_E263_I0.5310.71
36_L40_Y0.5300.71
495_S500_S0.5290.71
352_K545_A0.5290.71
322_S325_M0.5290.71
357_T384_Y0.5280.71
14_I26_L0.5280.71
158_P168_W0.5280.71
106_N109_A0.5270.71
272_Y277_L0.5270.71
411_K414_N0.5260.70
212_I227_E0.5250.70
56_H151_T0.5250.70
141_T145_A0.5230.70
216_L227_E0.5230.70
330_Y426_I0.5220.70
185_S300_K0.5210.70
104_I107_A0.5200.70
360_C531_Y0.5200.70
36_L69_H0.5200.70
93_D102_C0.5200.70
177_E509_Q0.5190.69
229_K233_I0.5190.69
362_I365_D0.5190.69
247_E259_R0.5180.69
235_K247_E0.5180.69
18_L45_V0.5180.69
451_G513_R0.5180.69
212_I223_A0.5180.69
188_E307_F0.5170.69
152_Y399_I0.5170.69
56_H61_P0.5160.69
116_P122_K0.5160.69
218_E228_D0.5160.69
241_I249_E0.5160.69
218_E221_E0.5160.69
14_I38_A0.5160.69
38_A62_V0.5150.69
177_E324_T0.5150.69
239_D247_E0.5140.69
472_Y495_S0.5140.69
369_T372_L0.5140.69
275_S281_D0.5130.68
361_L365_D0.5130.68
59_F507_V0.5120.68
225_Y230_Y0.5120.68
35_T450_E0.5120.68
27_Q326_Q0.5120.68
244_S262_M0.5120.68
407_R422_T0.5120.68
15_V44_K0.5100.68
28_A151_T0.5080.68
243_P246_E0.5070.68
411_K415_I0.5070.68
236_D251_L0.5070.68
52_V452_I0.5070.68
86_V132_F0.5060.67
396_V430_M0.5060.67
158_P161_R0.5050.67
241_I247_E0.5040.67
394_R433_L0.5040.67
261_I266_K0.5040.67
9_K346_A0.5040.67
364_I532_D0.5030.67
221_E226_S0.5020.67
217_K231_I0.5010.67
64_R76_G0.5010.67
62_V65_E0.5000.67
263_I268_V0.5000.67
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3crvA 1 0.9818 100 0.271 Contact Map
4a15A 1 0.9382 100 0.278 Contact Map
2vl7A 1 0.8036 100 0.329 Contact Map
1gkuB 1 0.6364 100 0.736 Contact Map
4ys0A 1 0.8636 100 0.754 Contact Map
4dduA 1 0.6673 100 0.764 Contact Map
3fhoA 2 0.5309 100 0.767 Contact Map
4w7sA 2 0.6145 100 0.776 Contact Map
4bgdA 1 0.6364 100 0.777 Contact Map
4q2cA 1 0.6891 100 0.78 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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