Q980F6 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q980F6 - Nicotinic acid phosphoribosyltransferase, putative

UniProt:	Q980F6	Sequences: MEFYIADFKQIKEGKVTDIYFERTLKTLEYLGIKDAKVRMEVHSYGLPKGYEWALFTGLEEVLHLLEGVPVNVYAMPEGTLFKEIEPVMIIEGNYLDFGIYETAFLGILRHYSSISTKAARLKFLAMDKTLFFFGLRSLHPALAPMADRAAYIGGMDGVSGAMSKEYLGVDPSGTMPHALMLIVGDNVKAWKAFDEAMGSEVPRITLVDTFEDERTEALKAATLLGKKLYGIRLDTPSSRRGNFRKIIQEVKWTLKIHGYDHVKIFASGGIDEDDIINLRDIVDGFGIGTSIAFPPSVDFSADIVEKFVDGKWVPFTKRGKWPGAKQVYRCGKLNDVITLMDQEHPSSDCKPLLQKYMENGKIIKPLPSPKEIREYVIKQLTELQSS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	387 (350)
Sequences:	3533 (1905)
Seq/√Len:	101.8

ECOLI - PNCB
BACSU - PNCB
HALSA - Q9HMH3
SULSO - Q980F6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
165_K	172_P	4.495	1.00
186_D	189_K	4.268	1.00
232_I	251_V	4.200	1.00
356_K	359_E	4.024	1.00
369_S	372_E	3.734	1.00
327_Q	352_P	3.464	1.00
192_K	224_L	3.051	1.00
67_E	363_I	3.030	1.00
223_T	260_Y	2.955	1.00
62_V	105_F	2.819	1.00
368_P	376_Y	2.759	1.00
93_G	98_F	2.744	1.00
27_T	180_L	2.684	1.00
158_G	173_S	2.550	1.00
208_V	251_V	2.535	1.00
188_V	192_K	2.520	1.00
74_Y	356_K	2.496	1.00
66_L	73_V	2.457	1.00
280_R	286_F	2.441	1.00
205_I	231_G	2.407	1.00
136_L	145_P	2.333	1.00
37_K	92_E	2.321	1.00
266_F	285_G	2.318	1.00
90_I	354_L	2.226	1.00
42_V	105_F	2.206	1.00
76_M	82_F	2.181	1.00
163_M	166_E	2.156	1.00
208_V	232_I	2.121	1.00
131_L	156_M	2.085	1.00
123_K	157_D	2.077	1.00
250_E	253_W	2.067	1.00
192_K	196_E	2.051	1.00
152_Y	374_R	2.025	1.00
77_P	355_Q	1.994	1.00
214_E	250_E	1.977	1.00
219_L	222_A	1.957	1.00
252_K	256_K	1.943	1.00
264_K	284_D	1.933	1.00
184_V	193_A	1.927	1.00
208_V	254_T	1.918	1.00
253_W	257_I	1.887	1.00
132_F	173_S	1.886	1.00
92_E	325_A	1.876	1.00
42_V	62_V	1.868	1.00
39_R	92_E	1.827	1.00
275_D	278_N	1.822	1.00
74_Y	359_E	1.820	1.00
355_Q	365_K	1.814	1.00
53_W	124_F	1.791	1.00
74_Y	92_E	1.741	1.00
136_L	161_G	1.737	1.00
218_A	221_A	1.728	1.00
53_W	120_A	1.727	1.00
152_Y	170_V	1.699	1.00
31_L	196_E	1.679	1.00
31_L	193_A	1.677	1.00
94_N	97_D	1.659	1.00
63_L	357_Y	1.649	1.00
217_E	221_A	1.648	1.00
368_P	372_E	1.634	1.00
129_K	280_R	1.621	1.00
220_K	224_L	1.616	1.00
56_F	59_L	1.612	1.00
228_K	262_H	1.611	1.00
248_I	267_A	1.609	1.00
42_V	109_L	1.605	1.00
62_V	89_M	1.601	1.00
147_A	293_A	1.600	1.00
132_F	158_G	1.580	1.00
66_L	101_Y	1.572	1.00
26_K	198_M	1.558	1.00
31_L	197_A	1.524	1.00
76_M	328_V	1.515	1.00
59_L	357_Y	1.514	1.00
44_S	47_L	1.512	1.00
63_L	358_M	1.506	1.00
30_Y	197_A	1.498	1.00
123_K	128_D	1.497	1.00
219_L	254_T	1.490	1.00
226_G	229_L	1.470	1.00
358_M	363_I	1.466	1.00
148_D	164_S	1.454	1.00
276_I	288_I	1.451	1.00
189_K	192_K	1.451	1.00
371_K	375_E	1.450	1.00
130_T	157_D	1.430	1.00
277_I	281_D	1.426	1.00
222_A	229_L	1.405	1.00
163_M	167_Y	1.390	1.00
117_T	121_R	1.385	1.00
118_K	121_R	1.384	1.00
129_K	286_F	1.384	1.00
231_G	263_V	1.370	0.99
222_A	225_L	1.370	0.99
332_G	351_K	1.362	0.99
176_M	181_M	1.353	0.99
89_M	109_L	1.345	0.99
152_Y	370_P	1.340	0.99
329_Y	352_P	1.336	0.99
26_K	30_Y	1.335	0.99
111_H	115_I	1.331	0.99
24_T	177_P	1.329	0.99
123_K	131_L	1.328	0.99
65_L	104_A	1.325	0.99
28_L	99_G	1.321	0.99
119_A	156_M	1.314	0.99
19_I	172_P	1.311	0.99
55_L	81_L	1.303	0.99
334_L	349_D	1.299	0.99
329_Y	339_T	1.288	0.99
357_Y	365_K	1.282	0.99
60_E	64_H	1.274	0.99
221_A	225_L	1.272	0.99
254_T	258_H	1.263	0.99
73_V	358_M	1.259	0.99
189_K	193_A	1.253	0.99
91_I	105_F	1.251	0.99
340_L	343_Q	1.244	0.99
357_Y	363_I	1.242	0.99
368_P	373_I	1.236	0.99
331_C	350_C	1.236	0.99
217_E	220_K	1.235	0.99
103_T	136_L	1.228	0.99
54_A	113_S	1.219	0.99
77_P	376_Y	1.210	0.99
57_T	116_S	1.208	0.99
188_V	220_K	1.206	0.99
339_T	343_Q	1.204	0.99
91_I	306_E	1.199	0.99
121_R	273_E	1.197	0.99
310_D	313_W	1.195	0.99
371_K	374_R	1.192	0.99
195_D	204_R	1.191	0.99
152_Y	171_D	1.189	0.99
218_A	223_T	1.188	0.99
67_E	362_K	1.185	0.98
63_L	363_I	1.173	0.98
132_F	285_G	1.169	0.98
122_L	131_L	1.169	0.98
352_P	356_K	1.158	0.98
218_A	222_A	1.155	0.98
251_V	254_T	1.153	0.98
25_L	69_V	1.148	0.98
19_I	162_A	1.144	0.98
140_H	144_A	1.140	0.98
270_G	303_D	1.124	0.98
327_Q	354_L	1.120	0.98
231_G	264_K	1.109	0.98
37_K	94_N	1.104	0.98
153_I	373_I	1.104	0.98
39_R	313_W	1.103	0.98
219_L	251_V	1.093	0.97
82_F	88_V	1.090	0.97
74_Y	90_I	1.083	0.97
351_K	355_Q	1.079	0.97
188_V	224_L	1.077	0.97
173_S	285_G	1.070	0.97
193_A	196_E	1.067	0.97
62_V	104_A	1.066	0.97
267_A	283_V	1.061	0.97
41_E	90_I	1.060	0.97
77_P	80_T	1.041	0.97
120_A	124_F	1.040	0.97
221_A	224_L	1.040	0.97
41_E	326_K	1.039	0.97
244_F	283_V	1.027	0.96
363_I	366_P	1.021	0.96
39_R	90_I	1.019	0.96
75_A	79_G	1.017	0.96
38_V	95_Y	1.016	0.96
295_P	300_F	1.014	0.96
321_K	326_K	1.012	0.96
272_D	291_S	1.010	0.96
205_I	266_F	1.008	0.96
30_Y	196_E	1.006	0.96
369_S	373_I	1.005	0.96
58_G	116_S	0.997	0.96
214_E	247_I	0.997	0.96
291_S	296_P	0.986	0.95
25_L	96_L	0.986	0.95
152_Y	371_K	0.982	0.95
217_E	222_A	0.979	0.95
111_H	139_L	0.974	0.95
62_V	109_L	0.974	0.95
26_K	197_A	0.964	0.95
40_M	99_G	0.963	0.95
47_L	54_A	0.961	0.95
372_E	375_E	0.958	0.95
17_T	22_E	0.958	0.95
297_S	300_F	0.956	0.94
59_L	368_P	0.956	0.94
78_E	149_R	0.956	0.94
218_A	225_L	0.954	0.94
356_K	364_I	0.944	0.94
319_R	326_K	0.938	0.94
365_K	368_P	0.938	0.94
358_M	364_I	0.932	0.94
182_L	210_T	0.928	0.94
42_V	89_M	0.925	0.93
159_V	174_G	0.923	0.93
76_M	80_T	0.919	0.93
359_E	362_K	0.916	0.93
341_M	344_E	0.913	0.93
142_A	163_M	0.913	0.93
321_K	325_A	0.911	0.93
260_Y	263_V	0.909	0.93
80_T	353_L	0.908	0.93
73_V	79_G	0.908	0.93
351_K	376_Y	0.906	0.93
118_K	122_L	0.904	0.93
245_R	249_Q	0.900	0.92
358_M	365_K	0.898	0.92
36_A	312_K	0.897	0.92
254_T	257_I	0.895	0.92
28_L	95_Y	0.895	0.92
180_L	184_V	0.894	0.92
366_P	372_E	0.890	0.92
121_R	125_L	0.889	0.92
90_I	325_A	0.887	0.92
95_Y	183_I	0.887	0.92
355_Q	371_K	0.884	0.92
76_M	86_E	0.884	0.92
112_Y	150_A	0.883	0.92
122_L	288_I	0.882	0.92
195_D	225_L	0.877	0.92
126_A	131_L	0.872	0.91
234_L	247_I	0.872	0.91
132_F	266_F	0.867	0.91
329_Y	350_C	0.857	0.91
219_L	223_T	0.856	0.90
66_L	104_A	0.855	0.90
327_Q	342_D	0.850	0.90
213_D	234_L	0.838	0.90
356_K	360_N	0.836	0.89
349_D	352_P	0.834	0.89
357_Y	364_I	0.834	0.89
243_N	278_N	0.828	0.89
35_D	94_N	0.827	0.89
296_P	301_S	0.823	0.89
192_K	225_L	0.821	0.89
86_E	328_V	0.820	0.89
56_F	76_M	0.817	0.88
65_L	69_V	0.817	0.88
135_G	139_L	0.815	0.88
157_D	374_R	0.813	0.88
56_F	88_V	0.808	0.88
373_I	376_Y	0.806	0.88
59_L	75_A	0.806	0.88
267_A	279_L	0.804	0.88
75_A	80_T	0.800	0.87
62_V	73_V	0.799	0.87
369_S	375_E	0.799	0.87
27_T	198_M	0.799	0.87
336_D	340_L	0.798	0.87
205_I	263_V	0.796	0.87
125_L	277_I	0.795	0.87
336_D	339_T	0.795	0.87
319_R	324_G	0.794	0.87
200_S	227_K	0.791	0.87
63_L	364_I	0.790	0.87
325_A	341_M	0.789	0.87
290_T	301_S	0.788	0.86
245_R	278_N	0.786	0.86
57_T	153_I	0.786	0.86
108_I	142_A	0.786	0.86
64_H	366_P	0.784	0.86
110_R	304_I	0.784	0.86
227_K	230_Y	0.781	0.86
134_F	158_G	0.780	0.86
113_S	304_I	0.780	0.86
229_L	263_V	0.779	0.86
189_K	196_E	0.779	0.86
101_Y	105_F	0.778	0.86
47_L	51_Y	0.778	0.86
131_L	276_I	0.777	0.86
41_E	309_V	0.777	0.86
122_L	125_L	0.775	0.86
129_K	284_D	0.773	0.85
135_G	293_A	0.770	0.85
252_K	284_D	0.769	0.85
195_D	221_A	0.766	0.85
44_S	304_I	0.765	0.85
331_C	334_L	0.765	0.85
44_S	54_A	0.764	0.85
144_A	147_A	0.762	0.85
16_V	136_L	0.761	0.85
122_L	276_I	0.760	0.84
61_E	64_H	0.758	0.84
321_K	324_G	0.757	0.84
151_A	292_I	0.753	0.84
76_M	79_G	0.753	0.84
217_E	225_L	0.751	0.84
31_L	184_V	0.746	0.83
49_K	295_P	0.743	0.83
217_E	223_T	0.742	0.83
14_G	65_L	0.742	0.83
234_L	267_A	0.741	0.83
300_F	307_K	0.740	0.83
153_I	370_P	0.739	0.83
351_K	372_E	0.737	0.83
188_V	225_L	0.736	0.83
73_V	80_T	0.735	0.82
55_L	58_G	0.735	0.82
64_H	68_G	0.735	0.82
213_D	247_I	0.733	0.82
187_N	217_E	0.732	0.82
164_S	170_V	0.729	0.82
169_G	371_K	0.729	0.82
16_V	142_A	0.729	0.82
27_T	197_A	0.727	0.82
220_K	223_T	0.724	0.81
111_H	147_A	0.719	0.81
34_K	96_L	0.718	0.81
117_T	120_A	0.718	0.81
269_G	275_D	0.717	0.81
218_A	224_L	0.715	0.81
264_K	285_G	0.714	0.81
356_K	365_K	0.713	0.80
319_R	322_W	0.712	0.80
173_S	266_F	0.709	0.80
191_W	206_T	0.709	0.80
230_Y	263_V	0.706	0.80
355_Q	372_E	0.705	0.80
42_V	106_L	0.705	0.80
270_G	291_S	0.703	0.80
232_I	265_I	0.701	0.79
200_S	228_K	0.700	0.79
352_P	355_Q	0.699	0.79
337_V	350_C	0.699	0.79
17_T	162_A	0.699	0.79
332_G	349_D	0.697	0.79
246_K	250_E	0.694	0.79
359_E	364_I	0.692	0.78
181_M	190_A	0.692	0.78
25_L	100_I	0.688	0.78
334_L	350_C	0.686	0.78
143_L	146_M	0.686	0.78
360_N	371_K	0.685	0.78
139_L	293_A	0.682	0.77
36_A	308_F	0.680	0.77
119_A	123_K	0.680	0.77
332_G	350_C	0.679	0.77
145_P	161_G	0.678	0.77
162_A	172_P	0.677	0.77
55_L	116_S	0.677	0.77
245_R	279_L	0.676	0.77
29_E	34_K	0.676	0.77
274_D	278_N	0.675	0.77
188_V	221_A	0.662	0.75
370_P	373_I	0.661	0.75
200_S	230_Y	0.659	0.75
131_L	288_I	0.656	0.75
344_E	371_K	0.649	0.74
64_H	67_E	0.649	0.74
16_V	107_G	0.648	0.74
328_V	338_I	0.648	0.74
171_D	374_R	0.646	0.74
326_K	329_Y	0.645	0.73
139_L	147_A	0.644	0.73
19_I	23_R	0.642	0.73
119_A	122_L	0.641	0.73
104_A	108_I	0.640	0.73
195_D	199_G	0.639	0.73
95_Y	99_G	0.639	0.73
123_K	126_A	0.639	0.73
252_K	265_I	0.638	0.73
151_A	156_M	0.637	0.73
62_V	66_L	0.637	0.73
325_A	354_L	0.637	0.73
208_V	234_L	0.636	0.72
278_N	281_D	0.634	0.72
15_K	166_E	0.631	0.72
246_K	278_N	0.631	0.72
192_K	221_A	0.631	0.72
32_G	193_A	0.630	0.72
328_V	354_L	0.630	0.72
270_G	290_T	0.628	0.71
256_K	259_G	0.627	0.71
110_R	114_S	0.627	0.71
360_N	375_E	0.627	0.71
150_A	154_G	0.626	0.71
192_K	227_K	0.622	0.71
245_R	248_I	0.622	0.71
114_S	294_F	0.620	0.71
60_E	373_I	0.619	0.70
219_L	224_L	0.618	0.70
301_S	304_I	0.617	0.70
56_F	82_F	0.616	0.70
37_K	312_K	0.615	0.70
357_Y	368_P	0.610	0.69
170_V	370_P	0.610	0.69
106_L	110_R	0.608	0.69
266_F	269_G	0.608	0.69
73_V	76_M	0.607	0.69
123_K	127_M	0.607	0.69
244_F	279_L	0.606	0.69
323_P	326_K	0.606	0.69
355_Q	366_P	0.605	0.69
319_R	325_A	0.604	0.69
351_K	369_S	0.602	0.68
232_I	254_T	0.602	0.68
339_T	348_S	0.600	0.68
160_S	175_T	0.600	0.68
75_A	357_Y	0.597	0.68
295_P	299_D	0.596	0.68
138_S	290_T	0.596	0.68
146_M	167_Y	0.593	0.67
327_Q	341_M	0.590	0.67
365_K	372_E	0.590	0.67
103_T	145_P	0.588	0.66
125_L	128_D	0.585	0.66
61_E	112_Y	0.584	0.66
115_I	292_I	0.583	0.66
246_K	249_Q	0.583	0.66
123_K	156_M	0.583	0.66
136_L	142_A	0.582	0.66
362_K	366_P	0.579	0.65
333_K	355_Q	0.579	0.65
56_F	75_A	0.579	0.65
146_M	163_M	0.578	0.65
199_G	228_K	0.575	0.65
111_H	140_H	0.574	0.65
65_L	101_Y	0.573	0.65
330_R	336_D	0.572	0.64
187_N	191_W	0.571	0.64
331_C	339_T	0.568	0.64
320_G	323_P	0.567	0.64
187_N	244_F	0.567	0.64
219_L	225_L	0.566	0.64
336_D	341_M	0.566	0.64
348_S	366_P	0.565	0.63
181_M	191_W	0.563	0.63
205_I	229_L	0.563	0.63
270_G	301_S	0.563	0.63
126_A	288_I	0.563	0.63
141_P	144_A	0.562	0.63
148_D	151_A	0.562	0.63
175_T	207_L	0.561	0.63
349_D	375_E	0.561	0.63
366_P	371_K	0.559	0.63
28_L	183_I	0.558	0.62
273_E	291_S	0.558	0.62
90_I	341_M	0.555	0.62
66_L	358_M	0.555	0.62
213_D	251_V	0.555	0.62
355_Q	360_N	0.554	0.62
182_L	270_G	0.553	0.62
314_V	371_K	0.551	0.62
234_L	283_V	0.549	0.61
301_S	305_V	0.548	0.61
364_I	373_I	0.547	0.61
159_V	236_T	0.547	0.61
223_T	258_H	0.547	0.61
372_E	376_Y	0.547	0.61
296_P	300_F	0.546	0.61
119_A	154_G	0.545	0.61
320_G	325_A	0.542	0.60
43_H	85_I	0.542	0.60
176_M	194_F	0.540	0.60
56_F	60_E	0.539	0.60
156_M	292_I	0.538	0.60
335_N	375_E	0.538	0.60
329_Y	348_S	0.538	0.60
21_F	136_L	0.537	0.60
342_D	352_P	0.534	0.59
365_K	376_Y	0.533	0.59
40_M	98_F	0.533	0.59
256_K	282_I	0.533	0.59
26_K	29_E	0.531	0.59
111_H	156_M	0.531	0.59
349_D	371_K	0.530	0.59
185_G	189_K	0.530	0.59
355_Q	368_P	0.530	0.59
28_L	38_V	0.530	0.59
91_I	98_F	0.530	0.59
342_D	371_K	0.529	0.58
80_T	351_K	0.529	0.58
229_L	260_Y	0.529	0.58
335_N	355_Q	0.529	0.58
338_I	342_D	0.528	0.58
67_E	358_M	0.527	0.58
28_L	40_M	0.527	0.58
185_G	316_F	0.526	0.58
344_E	348_S	0.526	0.58
73_V	101_Y	0.526	0.58
362_K	375_E	0.526	0.58
44_S	269_G	0.525	0.58
31_L	310_D	0.525	0.58
231_G	285_G	0.524	0.58
39_R	74_Y	0.523	0.58
348_S	365_K	0.522	0.57
54_A	302_A	0.521	0.57
339_T	344_E	0.519	0.57
205_I	285_G	0.518	0.57
58_G	79_G	0.518	0.57
57_T	150_A	0.518	0.57
76_M	353_L	0.517	0.57
249_Q	360_N	0.516	0.57
198_M	201_E	0.516	0.57
184_V	211_F	0.515	0.56
302_A	307_K	0.515	0.56
304_I	307_K	0.515	0.56
21_F	29_E	0.514	0.56
217_E	224_L	0.514	0.56
188_V	217_E	0.513	0.56
334_L	348_S	0.511	0.56
337_V	371_K	0.511	0.56
135_G	151_A	0.510	0.56
300_F	309_V	0.509	0.56
106_L	271_I	0.508	0.55
341_M	369_S	0.508	0.55
159_V	170_V	0.507	0.55
204_R	229_L	0.507	0.55
118_K	125_L	0.506	0.55
360_N	373_I	0.506	0.55
131_L	157_D	0.506	0.55
60_E	149_R	0.506	0.55
243_N	246_K	0.505	0.55
21_F	177_P	0.504	0.55
319_R	323_P	0.504	0.55
62_V	101_Y	0.503	0.55
219_L	258_H	0.502	0.55
201_E	205_I	0.502	0.55
349_D	369_S	0.502	0.55
92_E	359_E	0.500	0.54

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4yubA	2	0.9121	100	0.17	Contact Map
2i14A	5	0.9871	100	0.224	Contact Map
4lvfA	2	0.9225	100	0.242	Contact Map
2i1oA	5	0.9716	100	0.251	Contact Map
4mzyA	2	0.9638	100	0.253	Contact Map
1ybeA	2	0.8295	100	0.285	Contact Map
3os4A	1	0.8191	100	0.3	Contact Map
1vlpA	1	0.8475	100	0.31	Contact Map
1yirA	1	0.8191	100	0.322	Contact Map
4hl7A	4	0.845	100	0.324	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0102 seconds.