GREMLIN Database
Q980F5 - Phosphate regulatory protein, putative
UniProt: Q980F5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 351 (318)
Sequences: 331 (254)
Seq/√Len: 14.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
156_Y175_L4.1971.00
13_T17_S4.1541.00
222_E226_E4.0901.00
34_V46_V3.9211.00
6_V28_L3.8731.00
153_M176_E3.8641.00
221_E225_D3.6290.99
176_E221_E3.2990.99
154_L325_A3.0410.98
153_M221_E2.9340.97
180_D225_D2.7330.96
19_P22_W2.6200.94
178_E181_R2.5680.94
328_R334_E2.5590.94
157_L227_I2.5200.93
180_D221_E2.4910.93
146_L179_V2.4460.92
221_E334_E2.3990.91
176_E225_D2.3240.90
8_K11_K2.2800.89
7_Q13_T2.2790.89
23_V28_L2.2670.88
225_D334_E2.1310.85
104_R145_R2.1260.85
134_P185_L2.0670.83
9_F12_S2.0090.81
10_G76_R2.0000.81
2_E5_R1.9820.80
158_D167_T1.9660.80
222_E328_R1.9570.80
216_L270_L1.9550.80
4_R19_P1.9470.79
226_E334_E1.9340.79
11_K14_L1.9290.79
7_Q17_S1.9080.78
27_S126_I1.9040.78
153_M225_D1.9000.77
321_R328_R1.8980.77
160_G169_L1.8130.74
220_I280_E1.8080.74
91_I118_I1.8040.74
324_N331_P1.7980.73
36_L44_L1.7900.73
185_L189_Q1.7790.73
29_S32_E1.7730.72
4_R22_W1.7510.71
13_T23_V1.7450.71
169_L172_V1.7340.71
45_K91_I1.6920.69
109_T113_L1.6810.68
176_E180_D1.6640.67
10_G22_W1.6600.67
141_N145_R1.6540.67
322_L326_I1.6440.66
156_Y222_E1.6380.66
27_S274_D1.6250.65
222_E334_E1.6210.65
110_I128_I1.6200.65
176_E324_N1.6080.64
4_R7_Q1.5800.63
132_L218_K1.5670.62
13_T43_S1.5630.62
9_F328_R1.5520.62
156_Y168_F1.5490.61
193_A203_I1.5450.61
12_S212_G1.5390.61
157_L169_L1.5180.60
13_T129_Q1.5100.59
91_I216_L1.4860.58
113_L214_R1.4270.55
79_Y189_Q1.4250.55
334_E338_N1.4150.54
10_G225_D1.4070.54
5_R12_S1.3990.53
176_E222_E1.3970.53
200_A203_I1.3930.53
10_G20_A1.3900.53
9_F222_E1.3710.52
9_F15_M1.3650.52
18_L43_S1.3620.51
185_L200_A1.3470.51
204_G207_R1.3420.50
146_L224_A1.3410.50
226_E328_R1.3390.50
180_D331_P1.3330.50
190_L331_P1.3300.50
139_M196_N1.3240.49
14_L194_Q1.3200.49
9_F14_L1.3180.49
4_R10_G1.3150.49
158_D256_I1.3050.48
29_S34_V1.3030.48
136_K181_R1.2870.47
274_D293_I1.2840.47
9_F121_Q1.2800.47
255_Y319_N1.2740.47
180_D226_E1.2700.46
153_M180_D1.2700.46
10_G31_G1.2630.46
18_L125_T1.2580.46
18_L22_W1.2580.46
116_L181_R1.2570.46
6_V153_M1.2550.46
298_I319_N1.2450.45
191_L212_G1.2340.44
263_I329_M1.2260.44
20_A278_I1.1930.42
4_R13_T1.1920.42
229_E320_L1.1780.41
133_D136_K1.1750.41
14_L21_E1.1680.41
216_L265_H1.1670.41
221_E328_R1.1600.41
10_G19_P1.1580.40
107_K111_R1.1570.40
226_E324_N1.1550.40
103_L156_Y1.1540.40
171_E175_L1.1520.40
180_D324_N1.1400.39
320_L327_R1.1360.39
99_T294_T1.1340.39
223_A325_A1.1280.39
93_S264_D1.1270.39
321_R337_F1.1250.39
277_L293_I1.1250.39
9_F20_A1.1140.38
32_E338_N1.1100.38
4_R16_V1.1000.37
131_F137_Y1.0950.37
64_I294_T1.0950.37
205_V213_N1.0930.37
177_R230_I1.0900.37
111_R181_R1.0880.37
139_M298_I1.0880.37
153_M224_A1.0860.37
10_G221_E1.0850.37
177_R181_R1.0850.37
287_T291_V1.0740.36
289_R293_I1.0730.36
265_H284_E1.0730.36
336_A340_S1.0700.36
134_P199_L1.0690.36
250_N281_V1.0680.36
7_Q19_P1.0670.36
11_K15_M1.0490.35
211_V271_A1.0440.35
15_M234_L1.0420.34
211_V214_R1.0340.34
78_I109_T1.0290.34
250_N257_E1.0270.34
90_D188_R1.0210.33
87_D316_R1.0210.33
324_N328_R1.0190.33
178_E251_K1.0150.33
173_I176_E1.0120.33
224_A266_A1.0100.33
15_M222_E0.9990.32
239_P247_R0.9900.32
74_V182_L0.9900.32
44_L176_E0.9880.32
91_I273_E0.9850.32
156_Y226_E0.9810.32
145_R148_N0.9810.32
59_E88_R0.9760.31
32_E149_S0.9700.31
155_H178_E0.9660.31
26_V132_L0.9640.31
44_L330_E0.9640.31
136_K230_I0.9630.31
218_K267_V0.9620.31
43_S262_V0.9570.30
323_Y327_R0.9570.30
46_V69_V0.9570.30
12_S70_Q0.9550.30
13_T336_A0.9550.30
13_T19_P0.9530.30
130_S187_L0.9530.30
250_N300_E0.9500.30
110_I118_I0.9480.30
78_I317_A0.9440.30
222_E324_N0.9320.29
235_L300_E0.9320.29
176_E334_E0.9310.29
247_R259_T0.9300.29
31_G113_L0.9240.29
176_E331_P0.9230.29
121_Q334_E0.9230.29
23_V59_E0.9200.29
221_E224_A0.9160.29
14_L223_A0.9130.28
120_S175_L0.9110.28
283_E288_L0.9070.28
135_T246_K0.9050.28
214_R335_I0.9050.28
46_V257_E0.9040.28
318_L325_A0.9000.28
10_G13_T0.8950.28
9_F270_L0.8940.28
332_I337_F0.8810.27
122_T293_I0.8800.27
122_T153_M0.8800.27
150_I227_I0.8740.27
105_K160_G0.8740.27
83_I184_Y0.8730.27
189_Q193_A0.8720.27
62_I72_E0.8700.27
61_K127_Q0.8680.26
130_S136_K0.8630.26
107_K150_I0.8630.26
118_I129_Q0.8620.26
12_S91_I0.8610.26
119_V214_R0.8520.26
63_S156_Y0.8500.26
7_Q16_V0.8470.26
124_D255_Y0.8450.25
6_V44_L0.8430.25
189_Q192_L0.8410.25
263_I325_A0.8410.25
221_E226_E0.8400.25
11_K128_I0.8300.25
59_E90_D0.8280.25
62_I89_I0.8260.25
139_M143_I0.8250.25
246_K250_N0.8240.25
153_M334_E0.8230.25
174_E196_N0.8220.25
278_I282_M0.8180.24
188_R323_Y0.8170.24
180_D334_E0.8160.24
48_P142_L0.8150.24
7_Q22_W0.8150.24
5_R14_L0.8140.24
288_L315_L0.8130.24
178_E209_Q0.8100.24
176_E226_E0.8080.24
161_I234_L0.8070.24
121_Q175_L0.8040.24
3_V44_L0.8010.24
82_Y115_G0.8000.24
126_I177_R0.7990.24
107_K178_E0.7990.24
204_G322_L0.7990.24
46_V91_I0.7980.24
68_S126_I0.7960.23
8_K13_T0.7950.23
189_Q338_N0.7930.23
12_S153_M0.7930.23
20_A222_E0.7920.23
90_D160_G0.7910.23
78_I144_N0.7890.23
131_F176_E0.7870.23
187_L214_R0.7860.23
239_P311_L0.7840.23
91_I139_M0.7830.23
102_I170_Q0.7820.23
12_S141_N0.7790.23
47_Y80_S0.7770.23
107_K182_L0.7770.23
317_A320_L0.7680.22
6_V26_V0.7670.22
78_I337_F0.7670.22
16_V19_P0.7660.22
172_V234_L0.7630.22
146_L221_E0.7600.22
329_M333_T0.7580.22
36_L138_T0.7570.22
12_S48_P0.7560.22
6_V12_S0.7540.22
7_Q12_S0.7510.22
139_M152_Q0.7490.22
168_F226_E0.7480.22
118_I121_Q0.7470.22
30_P333_T0.7460.22
192_L201_Y0.7450.22
13_T22_W0.7450.22
290_R293_I0.7430.21
86_Y125_T0.7430.21
159_L168_F0.7420.21
5_R167_T0.7400.21
7_Q10_G0.7350.21
321_R334_E0.7350.21
219_A331_P0.7350.21
76_R181_R0.7340.21
17_S22_W0.7340.21
110_I218_K0.7330.21
72_E93_S0.7280.21
180_D222_E0.7270.21
112_N185_L0.7260.21
78_I327_R0.7250.21
33_S167_T0.7250.21
192_L199_L0.7190.21
6_V14_L0.7170.21
252_I299_S0.7160.20
109_T184_Y0.7160.20
79_Y145_R0.7160.20
227_I231_A0.7120.20
62_I262_V0.7110.20
226_E321_R0.7110.20
154_L260_S0.7090.20
80_S180_D0.7060.20
117_E178_E0.7030.20
247_R288_L0.7030.20
7_Q11_K0.7000.20
29_S247_R0.7000.20
44_L125_T0.6980.20
176_E179_V0.6970.20
79_Y338_N0.6960.20
121_Q279_N0.6910.20
32_E331_P0.6900.20
9_F137_Y0.6860.19
191_L331_P0.6850.19
36_L184_Y0.6840.19
32_E76_R0.6830.19
114_I132_L0.6790.19
132_L181_R0.6780.19
141_N330_E0.6770.19
17_S138_T0.6760.19
4_R17_S0.6720.19
320_L328_R0.6720.19
46_V271_A0.6720.19
106_V274_D0.6710.19
25_E259_T0.6700.19
12_S181_R0.6700.19
78_I150_I0.6690.19
83_I109_T0.6680.19
8_K34_V0.6670.19
40_E184_Y0.6660.19
269_V278_I0.6650.19
80_S282_M0.6650.19
328_R338_N0.6610.19
126_I145_R0.6610.19
43_S264_D0.6560.18
190_L211_V0.6560.18
298_I318_L0.6560.18
106_V177_R0.6540.18
30_P219_A0.6520.18
81_L107_K0.6480.18
46_V276_I0.6470.18
27_S227_I0.6460.18
6_V229_E0.6450.18
54_E99_T0.6450.18
12_S47_Y0.6440.18
159_L163_E0.6350.18
166_R235_L0.6330.18
101_D290_R0.6330.18
149_S271_A0.6330.18
182_L225_D0.6310.18
44_L204_G0.6300.18
134_P189_Q0.6290.18
82_Y334_E0.6280.18
117_E180_D0.6260.17
153_M179_V0.6250.17
279_N337_F0.6240.17
89_I252_I0.6240.17
93_S98_F0.6240.17
80_S224_A0.6230.17
116_L282_M0.6220.17
153_M321_R0.6190.17
178_E274_D0.6170.17
142_L186_A0.6160.17
104_R141_N0.6140.17
168_F222_E0.6140.17
10_G180_D0.6130.17
137_Y142_L0.6130.17
118_I267_V0.6110.17
247_R254_M0.6090.17
9_F334_E0.6070.17
172_V224_A0.6040.17
172_V284_E0.6010.17
18_L119_V0.5950.17
89_I130_S0.5950.17
226_E331_P0.5950.17
118_I197_R0.5950.17
163_E298_I0.5940.16
14_L266_A0.5930.16
137_Y179_V0.5930.16
212_G335_I0.5890.16
110_I298_I0.5860.16
6_V13_T0.5850.16
113_L184_Y0.5820.16
163_E269_V0.5810.16
34_V84_L0.5810.16
80_S200_A0.5810.16
106_V271_A0.5810.16
13_T188_R0.5800.16
143_I237_L0.5750.16
282_M285_L0.5750.16
54_E277_L0.5750.16
334_E337_F0.5720.16
39_D81_L0.5710.16
80_S221_E0.5700.16
193_A270_L0.5700.16
75_S275_T0.5700.16
220_I263_I0.5680.16
93_S121_Q0.5680.16
118_I135_T0.5680.16
190_L217_I0.5670.16
186_A217_I0.5660.16
222_E321_R0.5650.16
108_D239_P0.5640.16
142_L202_M0.5640.16
54_E252_I0.5620.16
20_A131_F0.5620.16
181_R209_Q0.5610.16
95_S171_E0.5610.16
162_K250_N0.5580.15
88_R129_Q0.5580.15
43_S119_V0.5570.15
182_L331_P0.5570.15
12_S76_R0.5570.15
52_K91_I0.5540.15
143_I229_E0.5530.15
131_F136_K0.5520.15
175_L222_E0.5510.15
31_G76_R0.5510.15
315_L318_L0.5480.15
229_E331_P0.5450.15
288_L300_E0.5440.15
123_T129_Q0.5440.15
179_V331_P0.5430.15
64_I250_N0.5430.15
94_K290_R0.5420.15
10_G16_V0.5420.15
167_T320_L0.5410.15
131_F185_L0.5390.15
9_F138_T0.5390.15
23_V83_I0.5390.15
18_L338_N0.5360.15
146_L185_L0.5340.15
113_L146_L0.5340.15
43_S91_I0.5330.15
321_R331_P0.5320.15
131_F169_L0.5320.15
298_I308_S0.5320.15
190_L218_K0.5310.15
17_S207_R0.5300.15
146_L229_E0.5300.15
155_H223_A0.5300.15
64_I167_T0.5290.15
113_L129_Q0.5290.15
94_K232_L0.5280.15
319_N326_I0.5270.15
8_K25_E0.5270.15
114_I337_F0.5260.15
16_V22_W0.5260.15
13_T130_S0.5240.14
248_L293_I0.5230.14
179_V267_V0.5230.14
191_L269_V0.5230.14
141_N208_I0.5230.14
320_L334_E0.5210.14
3_V336_A0.5190.14
108_D280_E0.5190.14
76_R128_I0.5190.14
59_E249_W0.5180.14
63_S173_I0.5180.14
131_F149_S0.5180.14
310_S314_V0.5170.14
208_I327_R0.5150.14
6_V182_L0.5140.14
113_L138_T0.5140.14
130_S178_E0.5110.14
38_V190_L0.5100.14
163_E257_E0.5080.14
246_K327_R0.5080.14
141_N148_N0.5080.14
135_T143_I0.5070.14
16_V248_L0.5060.14
114_I184_Y0.5050.14
158_D253_N0.5050.14
177_R180_D0.5050.14
109_T292_L0.5030.14
7_Q14_L0.5030.14
236_S314_V0.5030.14
162_K279_N0.5020.14
92_E181_R0.5010.14
14_L20_A0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1sumB 2 0.6182 99.9 0.749 Contact Map
1xwmA 2 0.6011 99.9 0.753 Contact Map
2i0mA 2 0.5869 99.9 0.755 Contact Map
1t72A 5 0.6097 99.9 0.761 Contact Map
4q25A 2 0.5983 99.9 0.766 Contact Map
2oltA 5 0.5584 99.7 0.806 Contact Map
3l39A 3 0.5755 98.8 0.88 Contact Map
2mrnA 2 0.1425 98.6 0.888 Contact Map
3o27A 2 0.1481 98.1 0.903 Contact Map
1mvfD 1 0.1254 98 0.905 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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