Q980E3 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q980E3 - Uncharacterized protein

UniProt:	Q980E3	Sequences: MIKIVGLSRIHITLFDLEGKYGRLDGGAGVALKYPRIVVRSGNCFKPEVSLPFDVPKICIEEDFEQHIGLGHTTQYLLSVAKLAAEYNFKRLNSYELAKLVKRGGTSGVGVYAFEYGGFIVDGGHSTKVKRELLPSDFSSAPPPPLIARLNFPWYIYVNVVRGGRRVFGKDEINAFKQAKLEGLDTLARVVLMELIPSVAERDLEGALNAISLIQDLGFKKVEVFLQTDEVKKLMNDMVKAGFPAGLSSFGPAVYTFVSSKREGDELISRFGGFVSEPNNEGAKVFWSTMSS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	292 (272)
Sequences:	350 (280)
Seq/√Len:	17.0

SULSO - Q980E3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
195_L	210_A	3.981	1.00
81_A	97_L	3.678	1.00
6_G	79_S	3.369	0.99
223_E	247_L	3.267	0.99
41_S	83_L	3.212	0.99
31_A	113_A	3.048	0.99
112_Y	146_L	2.866	0.98
158_V	253_A	2.841	0.98
247_L	250_F	2.820	0.98
30_V	156_I	2.747	0.97
16_D	22_G	2.710	0.97
223_E	250_F	2.687	0.97
113_A	120_I	2.680	0.97
220_K	247_L	2.679	0.97
186_T	213_L	2.634	0.97
220_K	223_E	2.632	0.97
185_D	189_R	2.435	0.95
16_D	19_G	2.418	0.95
152_F	199_V	2.386	0.94
114_F	283_A	2.284	0.93
224_V	247_L	2.237	0.92
123_G	147_I	2.225	0.92
85_A	91_R	2.195	0.91
89_F	213_L	2.008	0.87
38_V	62_E	1.989	0.86
14_L	106_T	1.970	0.86
94_S	115_E	1.954	0.85
47_P	55_V	1.939	0.85
106_T	220_K	1.919	0.84
152_F	156_I	1.887	0.83
218_G	223_E	1.864	0.82
25_D	106_T	1.818	0.81
13_T	247_L	1.801	0.80
108_G	122_D	1.797	0.80
5_V	284_K	1.797	0.80
123_G	145_P	1.790	0.80
106_T	247_L	1.787	0.80
95_Y	115_E	1.782	0.79
3_K	286_F	1.765	0.79
73_T	106_T	1.764	0.79
25_D	250_F	1.756	0.78
5_V	38_V	1.754	0.78
225_F	247_L	1.740	0.78
19_G	22_G	1.725	0.77
204_L	208_L	1.706	0.76
25_D	223_E	1.687	0.75
3_K	38_V	1.672	0.75
106_T	223_E	1.664	0.74
107_S	122_D	1.636	0.73
220_K	250_F	1.636	0.73
261_K	265_D	1.632	0.73
39_V	60_I	1.620	0.72
13_T	223_E	1.614	0.72
25_D	247_L	1.577	0.70
106_T	250_F	1.560	0.69
13_T	224_V	1.545	0.69
224_V	250_F	1.537	0.68
5_V	36_R	1.534	0.68
22_G	193_M	1.533	0.68
16_D	193_M	1.529	0.68
13_T	250_F	1.526	0.68
226_L	250_F	1.511	0.67
158_V	274_F	1.510	0.67
11_H	29_G	1.488	0.66
75_Q	114_F	1.483	0.65
121_V	196_I	1.483	0.65
220_K	224_V	1.465	0.64
42_G	57_K	1.462	0.64
152_F	280_N	1.442	0.63
58_I	83_L	1.405	0.61
75_Q	219_F	1.393	0.60
281_E	284_K	1.388	0.60
119_F	199_V	1.382	0.60
34_Y	62_E	1.374	0.59
225_F	250_F	1.372	0.59
73_T	77_L	1.360	0.58
9_R	27_G	1.346	0.58
108_G	214_I	1.318	0.56
31_A	279_N	1.315	0.56
188_A	253_A	1.292	0.54
16_D	21_Y	1.282	0.54
195_L	209_N	1.280	0.54
203_D	206_G	1.279	0.54
107_S	114_F	1.273	0.53
93_N	96_E	1.272	0.53
121_V	191_V	1.272	0.53
161_V	254_V	1.260	0.53
16_D	192_L	1.253	0.52
75_Q	107_S	1.250	0.52
43_N	87_Y	1.227	0.51
50_S	57_K	1.220	0.50
49_V	58_I	1.216	0.50
58_I	65_E	1.215	0.50
161_V	255_Y	1.210	0.50
29_G	110_G	1.205	0.49
258_V	267_L	1.199	0.49
15_F	278_P	1.193	0.49
181_L	189_R	1.188	0.48
18_E	193_M	1.187	0.48
157_Y	267_L	1.181	0.48
19_G	189_R	1.177	0.48
32_L	70_L	1.151	0.46
238_M	243_F	1.150	0.46
16_D	25_D	1.146	0.46
11_H	110_G	1.139	0.45
93_N	151_N	1.139	0.45
159_N	256_T	1.134	0.45
25_D	226_L	1.130	0.45
106_T	224_V	1.129	0.45
84_A	189_R	1.123	0.44
119_F	278_P	1.117	0.44
9_R	14_L	1.111	0.44
198_S	208_L	1.106	0.43
25_D	218_G	1.104	0.43
23_R	201_E	1.104	0.43
56_P	88_N	1.103	0.43
223_E	226_L	1.100	0.43
66_Q	230_E	1.096	0.43
16_D	145_P	1.095	0.43
4_I	120_I	1.095	0.43
85_A	97_L	1.094	0.43
37_I	64_F	1.092	0.43
190_V	210_A	1.082	0.42
176_F	219_F	1.079	0.42
28_A	121_V	1.071	0.41
14_L	27_G	1.053	0.40
28_A	257_F	1.049	0.40
179_A	254_V	1.048	0.40
5_V	285_V	1.036	0.39
74_T	107_S	1.032	0.39
110_G	249_S	1.030	0.39
25_D	220_K	1.013	0.38
31_A	280_N	1.010	0.38
40_R	61_E	0.994	0.37
143_P	218_G	0.991	0.37
193_M	228_T	0.990	0.37
166_R	215_Q	0.989	0.37
109_V	248_S	0.979	0.36
33_K	276_S	0.978	0.36
19_G	193_M	0.974	0.36
9_R	246_G	0.971	0.36
90_K	266_E	0.969	0.36
31_A	120_I	0.965	0.35
105_G	223_E	0.959	0.35
82_K	94_S	0.951	0.35
14_L	25_D	0.949	0.35
22_G	81_A	0.946	0.34
246_G	255_Y	0.942	0.34
13_T	220_K	0.932	0.34
73_T	169_G	0.928	0.33
39_V	269_S	0.924	0.33
29_G	249_S	0.922	0.33
218_G	226_L	0.920	0.33
48_E	79_S	0.919	0.33
119_F	256_T	0.916	0.33
113_A	143_P	0.915	0.33
12_I	244_P	0.912	0.33
207_A	256_T	0.906	0.32
13_T	225_F	0.900	0.32
145_P	192_L	0.893	0.32
43_N	96_E	0.889	0.31
7_L	113_A	0.886	0.31
21_Y	188_A	0.884	0.31
198_S	210_A	0.884	0.31
12_I	199_V	0.882	0.31
228_T	255_Y	0.880	0.31
55_V	88_N	0.879	0.31
175_A	250_F	0.878	0.31
62_E	275_V	0.875	0.31
105_G	125_H	0.873	0.31
125_H	141_A	0.864	0.30
109_V	278_P	0.860	0.30
30_V	285_V	0.858	0.30
108_G	215_Q	0.855	0.30
114_F	219_F	0.855	0.30
16_D	123_G	0.853	0.30
17_L	23_R	0.851	0.29
78_L	114_F	0.850	0.29
114_F	166_R	0.848	0.29
218_G	247_L	0.846	0.29
17_L	31_A	0.843	0.29
65_E	247_L	0.840	0.29
179_A	184_L	0.839	0.29
9_R	67_H	0.839	0.29
106_T	227_Q	0.839	0.29
189_R	193_M	0.837	0.29
12_I	30_V	0.836	0.29
40_R	59_C	0.834	0.29
218_G	250_F	0.833	0.29
19_G	123_G	0.829	0.28
13_T	25_D	0.816	0.28
151_N	178_Q	0.816	0.28
8_S	35_P	0.814	0.28
122_D	215_Q	0.810	0.27
78_L	282_G	0.807	0.27
198_S	279_N	0.807	0.27
157_Y	238_M	0.801	0.27
214_I	241_A	0.801	0.27
123_G	184_L	0.791	0.27
142_P	285_V	0.791	0.27
91_R	97_L	0.790	0.26
74_T	122_D	0.790	0.26
240_K	277_E	0.789	0.26
32_L	260_S	0.787	0.26
5_V	286_F	0.783	0.26
85_A	88_N	0.782	0.26
154_W	207_A	0.780	0.26
121_V	157_Y	0.776	0.26
281_E	285_V	0.775	0.26
27_G	109_V	0.772	0.26
107_S	219_F	0.772	0.26
121_V	257_F	0.771	0.26
67_H	72_H	0.770	0.26
27_G	111_V	0.769	0.26
95_Y	109_V	0.769	0.26
27_G	161_V	0.768	0.25
78_L	107_S	0.764	0.25
98_A	115_E	0.763	0.25
75_Q	109_V	0.762	0.25
212_S	244_P	0.760	0.25
75_Q	154_W	0.758	0.25
81_A	101_V	0.756	0.25
223_E	232_K	0.756	0.25
196_I	208_L	0.754	0.25
60_I	70_L	0.750	0.25
62_E	68_I	0.747	0.25
80_V	85_A	0.746	0.24
82_K	90_K	0.743	0.24
154_W	219_F	0.741	0.24
208_L	243_F	0.741	0.24
60_I	202_R	0.741	0.24
14_L	247_L	0.738	0.24
84_A	242_G	0.736	0.24
220_K	225_F	0.735	0.24
160_V	253_A	0.732	0.24
34_Y	279_N	0.729	0.24
74_T	154_W	0.729	0.24
241_A	270_R	0.728	0.24
82_K	114_F	0.728	0.24
9_R	72_H	0.728	0.24
10_I	153_P	0.727	0.24
17_L	34_Y	0.725	0.24
4_I	9_R	0.724	0.24
7_L	189_R	0.723	0.23
38_V	61_E	0.720	0.23
38_V	240_K	0.719	0.23
84_A	245_A	0.717	0.23
100_L	270_R	0.716	0.23
14_L	220_K	0.716	0.23
144_P	179_A	0.714	0.23
75_Q	215_Q	0.711	0.23
106_T	169_G	0.709	0.23
12_I	70_L	0.707	0.23
46_K	202_R	0.704	0.23
148_A	200_A	0.704	0.23
227_Q	250_F	0.698	0.22
156_I	257_F	0.697	0.22
11_H	249_S	0.694	0.22
14_L	112_Y	0.693	0.22
92_L	100_L	0.689	0.22
61_E	91_R	0.688	0.22
35_P	276_S	0.686	0.22
13_T	64_F	0.684	0.22
6_G	258_V	0.684	0.22
199_V	266_E	0.681	0.22
40_R	168_F	0.681	0.22
74_T	103_R	0.680	0.22
158_V	198_S	0.680	0.22
96_E	266_E	0.679	0.22
14_L	250_F	0.679	0.22
105_G	220_K	0.665	0.21
18_E	156_I	0.663	0.21
97_L	111_V	0.663	0.21
107_S	176_F	0.661	0.21
8_S	64_F	0.660	0.21
124_G	144_P	0.659	0.21
25_D	221_K	0.658	0.21
14_L	254_V	0.654	0.21
169_G	222_V	0.654	0.21
8_S	14_L	0.654	0.21
3_K	277_E	0.649	0.20
86_E	170_K	0.649	0.20
12_I	222_V	0.646	0.20
231_V	254_V	0.643	0.20
86_E	283_A	0.643	0.20
213_L	217_L	0.641	0.20
46_K	50_S	0.641	0.20
7_L	31_A	0.641	0.20
23_R	184_L	0.640	0.20
105_G	218_G	0.638	0.20
158_V	179_A	0.638	0.20
80_V	148_A	0.637	0.20
169_G	188_A	0.637	0.20
114_F	122_D	0.628	0.20
27_G	213_L	0.627	0.20
196_I	246_G	0.627	0.20
113_A	156_I	0.626	0.20
82_K	283_A	0.625	0.20
3_K	60_I	0.625	0.20
74_T	124_G	0.625	0.20
208_L	244_P	0.624	0.20
152_F	278_P	0.623	0.19
14_L	223_E	0.622	0.19
75_Q	166_R	0.620	0.19
109_V	173_I	0.620	0.19
49_V	99_K	0.619	0.19
65_E	223_E	0.618	0.19
41_S	56_P	0.618	0.19
20_K	27_G	0.617	0.19
44_C	285_V	0.616	0.19
27_G	223_E	0.616	0.19
70_L	176_F	0.615	0.19
14_L	219_F	0.613	0.19
47_P	58_I	0.612	0.19
172_E	251_G	0.612	0.19
69_G	251_G	0.612	0.19
69_G	172_E	0.612	0.19
24_L	51_L	0.611	0.19
174_N	257_F	0.610	0.19
179_A	224_V	0.605	0.19
162_R	202_R	0.604	0.19
15_F	188_A	0.603	0.19
27_G	121_V	0.603	0.19
107_S	124_G	0.599	0.19
3_K	8_S	0.596	0.18
88_N	112_Y	0.596	0.18
119_F	198_S	0.593	0.18
176_F	242_G	0.593	0.18
216_D	224_V	0.593	0.18
43_N	178_Q	0.593	0.18
4_I	11_H	0.592	0.18
5_V	269_S	0.591	0.18
10_I	247_L	0.588	0.18
186_T	284_K	0.587	0.18
60_I	77_L	0.587	0.18
238_M	246_G	0.586	0.18
42_G	240_K	0.583	0.18
14_L	107_S	0.582	0.18
4_I	100_L	0.582	0.18
98_A	219_F	0.580	0.18
93_N	163_G	0.579	0.18
4_I	76_Y	0.576	0.18
56_P	269_S	0.575	0.18
208_L	256_T	0.571	0.18
12_I	152_F	0.569	0.18
220_K	227_Q	0.568	0.17
16_D	189_R	0.567	0.17
213_L	216_D	0.567	0.17
34_Y	37_I	0.566	0.17
122_D	144_P	0.566	0.17
85_A	92_L	0.565	0.17
75_Q	122_D	0.562	0.17
7_L	279_N	0.561	0.17
156_I	167_V	0.560	0.17
45_F	253_A	0.559	0.17
190_V	213_L	0.559	0.17
146_L	192_L	0.558	0.17
61_E	286_F	0.556	0.17
212_S	239_V	0.555	0.17
125_H	246_G	0.553	0.17
187_L	222_V	0.551	0.17
68_I	188_A	0.549	0.17
93_N	268_I	0.545	0.17
57_K	178_Q	0.545	0.17
16_D	188_A	0.545	0.17
144_P	148_A	0.544	0.17
49_V	211_I	0.540	0.17
16_D	231_V	0.538	0.16
191_V	245_A	0.538	0.16
191_V	214_I	0.537	0.16
108_G	246_G	0.537	0.16
120_I	275_V	0.537	0.16
79_S	203_D	0.534	0.16
14_L	176_F	0.534	0.16
208_L	259_S	0.533	0.16
81_A	253_A	0.531	0.16
38_V	79_S	0.529	0.16
222_V	258_V	0.529	0.16
106_T	175_A	0.529	0.16
4_I	14_L	0.528	0.16
25_D	224_V	0.528	0.16
184_L	231_V	0.528	0.16
10_I	255_Y	0.527	0.16
74_T	78_L	0.527	0.16
88_N	211_I	0.525	0.16
175_A	228_T	0.524	0.16
168_F	176_F	0.523	0.16
17_L	167_V	0.522	0.16
194_E	285_V	0.521	0.16
3_K	236_N	0.521	0.16
11_H	27_G	0.521	0.16
98_A	250_F	0.518	0.16
98_A	114_F	0.517	0.16
115_E	146_L	0.517	0.16
229_D	233_K	0.516	0.16
221_K	227_Q	0.516	0.16
126_S	221_K	0.515	0.16
268_I	272_G	0.513	0.16
61_E	170_K	0.509	0.16
200_A	204_L	0.506	0.15
75_Q	250_F	0.505	0.15
6_G	76_Y	0.505	0.15
46_K	267_L	0.504	0.15
82_K	115_E	0.504	0.15
14_L	218_G	0.503	0.15
23_R	122_D	0.501	0.15
154_W	215_Q	0.501	0.15
238_M	254_V	0.500	0.15

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3hulA	4	0.8219	100	0.716	Contact Map
3qt5A	2	0.9247	100	0.723	Contact Map
2cz9A	1	0.863	100	0.725	Contact Map
4rpfA	2	0.8801	100	0.725	Contact Map
1h72C	2	0.8562	100	0.728	Contact Map
4p52A	2	0.863	100	0.729	Contact Map
3pyfA	1	0.863	100	0.729	Contact Map
2gs8A	1	0.8973	100	0.73	Contact Map
4rksA	1	0.9041	100	0.735	Contact Map
2v8pA	1	0.8219	100	0.735	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0095 seconds.