Q980D8 - SULSO - GREMLIN Contacts

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Q980D8 - Na(+)/H(+) antiporter

UniProt:	Q980D8	Sequences: MVSLLLISLLYLGIMLIAAKISEEIFRRIGLVTFVGPILMGILLGNGVFGVIQINEIISFITSLGIVFLLFLAGAEEFNVENRPNANVFLAVILESIIPFSVILVAIYIIGFKNYLILIVPLAMSSAGPLSRMLMDVKISDNRISNLIFQQVILIEIIFVILFAILLKTSEILITIIEIFLVFAFTIMFGRTLAKILEKIEYYFKAREIEFASLIAIILIIGYLAELYKFNSAISAFFLGILLKDYLKDRPELLERLHAFTYGFFEPLFFLGIGLYVTKINASIILFSLLFFSLIIASKFLAGFISSKILNIKGKINGFATSVKGGVDSSLLLTGLTLGYINEFMYSFSILAISLSALIVPLLFQINFKISNKISESKKVKLSQEVIKLQIKPLYASCEENLRSVISKISERGVRGIVVVNYENKPLGYVSIQTLLEIDPELYESTKACEVPLDEVPIEYDNVKVIDLLRKFRETEKPVIAIINKEGVLVTTVYERELARFLISF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	505 (435)
Sequences:	8088 (5926)
Seq/√Len:	284.1

ECOLI - YBAL KEFB KEFC NHAP2 YJCE
BACSU - YJBQ NHAK YHAU
HALSA - Q9HNK1
SULSO - Q980D8 Q97UN8 Q97Z08

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
336_L	339_G	4.987	1.00
105_V	109_I	4.133	1.00
108_Y	112_F	4.037	1.00
177_I	181_L	3.930	1.00
292_F	355_L	3.909	1.00
335_G	338_L	3.416	1.00
191_R	195_K	3.414	1.00
335_G	339_G	3.409	1.00
195_K	199_K	3.280	1.00
175_T	182_V	3.189	1.00
104_L	108_Y	3.180	1.00
174_I	178_E	2.939	1.00
181_L	185_F	2.856	1.00
423_E	426_P	2.700	1.00
371_S	374_I	2.593	1.00
173_L	177_I	2.531	1.00
366_I	370_I	2.456	1.00
289_L	293_S	2.445	1.00
395_Y	406_I	2.421	1.00
102_V	298_S	2.410	1.00
334_T	339_G	2.394	1.00
106_A	294_L	2.385	1.00
328_D	349_S	2.358	1.00
304_F	318_G	2.330	1.00
320_A	363_L	2.325	1.00
191_R	194_A	2.316	1.00
180_F	184_A	2.314	1.00
335_G	340_Y	2.313	1.00
111_G	114_N	2.309	1.00
192_T	196_I	2.307	1.00
192_T	195_K	2.298	1.00
194_A	198_E	2.293	1.00
286_L	290_L	2.284	1.00
365_Q	369_K	2.282	1.00
107_I	115_Y	2.232	1.00
175_T	179_I	2.221	1.00
300_F	319_F	2.188	1.00
104_L	119_I	2.181	1.00
199_K	202_Y	2.094	1.00
105_V	108_Y	2.093	1.00
258_H	261_T	2.079	1.00
257_L	261_T	2.029	1.00
187_I	191_R	2.028	1.00
49_F	52_I	2.017	1.00
397_S	402_L	2.010	1.00
175_T	178_E	2.002	1.00
195_K	198_E	2.001	1.00
104_L	112_F	1.996	1.00
367_N	371_S	1.950	1.00
196_I	200_I	1.942	1.00
176_I	180_F	1.868	1.00
285_I	289_L	1.867	1.00
121_P	332_L	1.861	1.00
198_E	201_E	1.850	1.00
445_S	449_C	1.841	1.00
334_T	338_L	1.804	1.00
182_V	185_F	1.800	1.00
444_E	447_K	1.790	1.00
182_V	186_T	1.789	1.00
342_N	345_M	1.780	1.00
332_L	349_S	1.738	1.00
105_V	112_F	1.733	1.00
291_F	352_A	1.716	1.00
430_V	433_Q	1.696	1.00
178_E	181_L	1.680	1.00
160_V	331_L	1.667	1.00
110_I	115_Y	1.664	1.00
100_F	162_L	1.658	1.00
56_E	59_S	1.649	1.00
428_G	432_I	1.645	1.00
426_P	430_V	1.628	1.00
179_I	182_V	1.624	1.00
387_I	390_Q	1.609	1.00
399_E	402_L	1.603	1.00
252_E	256_R	1.591	1.00
39_L	43_L	1.590	1.00
104_L	116_L	1.574	1.00
248_K	251_P	1.572	1.00
178_E	182_V	1.555	1.00
368_F	371_S	1.555	1.00
377_S	380_V	1.553	1.00
288_S	351_L	1.533	1.00
182_V	190_G	1.532	1.00
334_T	337_T	1.529	1.00
22_S	40_M	1.523	1.00
17_I	216_A	1.515	1.00
336_L	346_Y	1.507	1.00
148_I	320_A	1.501	1.00
367_N	370_I	1.497	1.00
366_I	369_K	1.488	1.00
256_R	261_T	1.481	1.00
172_I	175_T	1.446	1.00
395_Y	405_V	1.444	1.00
440_P	445_S	1.443	1.00
179_I	183_F	1.441	1.00
222_G	232_S	1.436	1.00
257_L	260_F	1.435	1.00
172_I	176_I	1.433	1.00
395_Y	402_L	1.433	1.00
336_L	340_Y	1.429	1.00
184_A	188_M	1.426	1.00
427_L	430_V	1.421	1.00
48_V	52_I	1.421	1.00
423_E	427_L	1.414	1.00
409_I	413_G	1.410	1.00
420_V	423_E	1.408	1.00
355_L	359_I	1.407	1.00
398_C	406_I	1.402	1.00
444_E	448_A	1.397	1.00
100_F	120_V	1.393	1.00
442_L	448_A	1.379	1.00
426_P	429_Y	1.376	1.00
305_I	309_I	1.376	1.00
424_N	427_L	1.366	1.00
182_V	194_A	1.366	1.00
444_E	449_C	1.355	1.00
287_F	348_F	1.348	1.00
181_L	191_R	1.343	1.00
112_F	115_Y	1.343	1.00
107_I	291_F	1.331	1.00
294_L	298_S	1.326	1.00
107_I	110_I	1.326	1.00
395_Y	399_E	1.317	1.00
221_I	239_L	1.306	1.00
370_I	374_I	1.305	1.00
197_L	201_E	1.305	1.00
198_E	202_Y	1.298	1.00
401_N	406_I	1.297	1.00
189_F	193_L	1.294	1.00
173_L	176_I	1.289	1.00
194_A	201_E	1.279	1.00
441_E	444_E	1.279	1.00
269_F	326_G	1.279	1.00
26_F	36_G	1.272	1.00
199_K	203_Y	1.269	1.00
442_L	449_C	1.267	1.00
295_I	352_A	1.266	1.00
292_F	356_S	1.251	1.00
443_Y	447_K	1.248	1.00
420_V	436_L	1.248	1.00
348_F	352_A	1.248	1.00
101_S	105_V	1.242	1.00
182_V	198_E	1.242	1.00
446_T	449_C	1.241	1.00
188_M	191_R	1.228	1.00
103_I	107_I	1.226	1.00
429_Y	432_I	1.224	1.00
425_K	429_Y	1.223	1.00
341_I	344_F	1.220	1.00
89_F	92_V	1.217	1.00
250_R	258_H	1.213	1.00
308_K	311_N	1.204	1.00
442_L	446_T	1.197	1.00
398_C	402_L	1.195	1.00
118_L	349_S	1.194	1.00
91_A	303_G	1.194	1.00
175_T	186_T	1.192	1.00
194_A	200_I	1.187	1.00
390_Q	393_P	1.184	1.00
398_C	403_R	1.180	1.00
323_V	360_V	1.176	1.00
410_S	413_G	1.171	1.00
192_T	198_E	1.168	1.00
22_S	43_L	1.165	1.00
435_L	438_I	1.164	1.00
67_V	222_G	1.157	1.00
119_I	123_A	1.154	1.00
421_N	427_L	1.149	1.00
253_L	257_L	1.140	1.00
101_S	104_L	1.140	1.00
111_G	115_Y	1.127	1.00
278_T	347_S	1.126	1.00
194_A	199_K	1.113	1.00
417_I	420_V	1.111	1.00
217_I	239_L	1.109	1.00
108_Y	115_Y	1.101	1.00
288_S	348_F	1.097	1.00
438_I	445_S	1.092	1.00
102_V	302_A	1.091	1.00
420_V	427_L	1.091	1.00
307_S	314_G	1.090	1.00
246_Y	250_R	1.085	1.00
419_V	424_N	1.078	1.00
125_S	130_L	1.078	1.00
402_L	406_I	1.075	1.00
437_E	442_L	1.074	1.00
389_L	392_K	1.073	1.00
172_I	178_E	1.072	1.00
220_I	224_L	1.072	1.00
441_E	448_A	1.061	1.00
284_I	287_F	1.060	1.00
403_R	406_I	1.055	1.00
174_I	177_I	1.055	1.00
256_R	259_A	1.053	1.00
428_G	431_S	1.050	1.00
435_L	443_Y	1.050	1.00
96_S	158_I	1.043	1.00
190_G	194_A	1.041	1.00
411_E	415_R	1.040	1.00
445_S	448_A	1.038	1.00
22_S	26_F	1.035	1.00
175_T	185_F	1.035	1.00
298_S	302_A	1.025	1.00
441_E	445_S	1.023	1.00
328_D	353_I	1.023	1.00
387_I	391_I	1.021	1.00
378_K	381_K	1.017	1.00
193_L	198_E	1.017	1.00
442_L	445_S	1.016	1.00
434_T	438_I	1.014	1.00
43_L	48_V	1.013	1.00
87_N	147_L	1.008	1.00
72_L	76_E	1.007	1.00
410_S	433_Q	1.006	1.00
288_S	292_F	1.004	1.00
188_M	192_T	1.002	1.00
79_N	82_N	1.001	1.00
92_V	95_E	0.997	1.00
10_L	13_G	0.996	1.00
57_I	60_F	0.992	1.00
226_E	232_S	0.991	1.00
395_Y	398_C	0.989	1.00
41_G	45_G	0.985	1.00
423_E	430_V	0.977	1.00
250_R	257_L	0.972	1.00
20_K	23_E	0.970	1.00
121_P	331_L	0.968	1.00
399_E	406_I	0.964	1.00
419_V	432_I	0.964	1.00
118_L	122_L	0.963	1.00
429_Y	433_Q	0.960	1.00
193_L	197_L	0.959	1.00
251_P	257_L	0.957	1.00
414_V	417_I	0.955	1.00
401_N	405_V	0.947	1.00
397_S	406_I	0.945	1.00
401_N	404_S	0.940	1.00
89_F	93_I	0.936	1.00
197_L	200_I	0.936	1.00
27_R	30_G	0.934	1.00
173_L	191_R	0.933	1.00
256_R	260_F	0.928	1.00
427_L	437_E	0.919	1.00
98_I	302_A	0.918	1.00
441_E	449_C	0.918	1.00
304_F	316_I	0.918	1.00
189_F	192_T	0.917	1.00
369_K	373_K	0.916	1.00
85_N	89_F	0.916	1.00
402_L	405_V	0.915	1.00
127_A	152_V	0.914	1.00
195_K	200_I	0.912	1.00
134_L	145_S	0.912	1.00
440_P	447_K	0.911	1.00
398_C	405_V	0.907	1.00
358_L	362_L	0.903	1.00
436_L	445_S	0.902	1.00
87_N	90_L	0.901	1.00
438_I	442_L	0.900	1.00
186_T	190_G	0.899	1.00
125_S	326_G	0.896	1.00
148_I	317_N	0.895	1.00
19_A	23_E	0.892	1.00
84_P	87_N	0.891	1.00
412_R	415_R	0.890	1.00
43_L	46_N	0.889	1.00
223_Y	227_L	0.889	1.00
388_K	391_I	0.887	1.00
181_L	184_A	0.886	1.00
383_S	386_V	0.885	1.00
324_K	328_D	0.884	1.00
186_T	191_R	0.883	1.00
153_I	237_F	0.883	1.00
409_I	412_R	0.881	1.00
117_I	335_G	0.881	1.00
80_V	83_R	0.879	1.00
419_V	422_Y	0.879	1.00
99_P	103_I	0.878	1.00
283_S	286_L	0.877	1.00
443_Y	449_C	0.877	1.00
419_V	426_P	0.876	1.00
126_S	155_I	0.875	1.00
175_T	181_L	0.875	1.00
295_I	324_K	0.872	1.00
314_G	318_G	0.870	1.00
181_L	230_F	0.869	1.00
424_N	430_V	0.869	1.00
93_I	97_I	0.869	1.00
419_V	423_E	0.866	1.00
46_N	278_T	0.864	1.00
124_M	159_F	0.862	1.00
44_L	275_L	0.858	1.00
213_S	217_I	0.858	1.00
249_D	254_L	0.856	1.00
336_L	343_E	0.856	1.00
50_G	53_Q	0.852	1.00
130_L	133_M	0.846	1.00
396_A	402_L	0.845	1.00
222_G	236_A	0.844	1.00
134_L	140_S	0.843	1.00
370_I	373_K	0.842	1.00
386_V	391_I	0.841	1.00
175_T	194_A	0.841	1.00
388_K	392_K	0.840	1.00
26_F	30_G	0.836	1.00
422_Y	426_P	0.836	1.00
179_I	194_A	0.836	1.00
399_E	403_R	0.832	1.00
172_I	190_G	0.832	1.00
404_S	407_S	0.830	1.00
289_L	292_F	0.829	1.00
357_A	360_V	0.829	1.00
402_L	421_N	0.826	1.00
426_P	431_S	0.824	1.00
252_E	255_E	0.824	1.00
343_E	347_S	0.824	1.00
249_D	252_E	0.823	1.00
417_I	426_P	0.821	1.00
437_E	445_S	0.821	1.00
100_F	123_A	0.817	1.00
427_L	435_L	0.815	1.00
438_I	448_A	0.812	0.99
194_A	197_L	0.810	0.99
181_L	190_G	0.808	0.99
273_I	326_G	0.807	0.99
386_V	389_L	0.805	0.99
417_I	434_T	0.805	0.99
152_V	155_I	0.804	0.99
106_A	109_I	0.802	0.99
424_N	428_G	0.801	0.99
289_L	355_L	0.800	0.99
395_Y	403_R	0.800	0.99
441_E	447_K	0.800	0.99
344_F	348_F	0.793	0.99
437_E	448_A	0.791	0.99
88_V	107_I	0.787	0.99
324_K	353_I	0.785	0.99
129_P	357_A	0.784	0.99
421_N	426_P	0.782	0.99
117_I	121_P	0.781	0.99
291_F	348_F	0.780	0.99
193_L	196_I	0.775	0.99
179_I	190_G	0.775	0.99
284_I	344_F	0.774	0.99
278_T	281_N	0.773	0.99
187_I	190_G	0.772	0.99
292_F	296_I	0.766	0.99
425_K	428_G	0.766	0.99
13_G	17_I	0.760	0.99
427_L	431_S	0.755	0.99
402_L	413_G	0.755	0.99
196_I	202_Y	0.755	0.99
407_S	411_E	0.754	0.99
107_I	119_I	0.754	0.99
304_F	308_K	0.754	0.99
430_V	435_L	0.752	0.99
439_D	443_Y	0.751	0.99
434_T	437_E	0.751	0.99
94_L	97_I	0.751	0.99
97_I	101_S	0.749	0.99
296_I	359_I	0.749	0.99
402_L	407_S	0.747	0.99
177_I	182_V	0.747	0.99
59_S	272_G	0.746	0.99
253_L	256_R	0.745	0.99
293_S	297_A	0.745	0.99
440_P	449_C	0.742	0.99
255_E	258_H	0.740	0.99
98_I	101_S	0.738	0.99
425_K	432_I	0.736	0.99
439_D	442_L	0.736	0.99
300_F	304_F	0.734	0.99
417_I	423_E	0.733	0.99
177_I	180_F	0.732	0.99
196_I	199_K	0.732	0.99
419_V	435_L	0.731	0.99
215_I	260_F	0.730	0.99
424_N	432_I	0.729	0.99
195_K	202_Y	0.727	0.99
21_I	24_E	0.726	0.99
112_F	116_L	0.724	0.99
435_L	440_P	0.724	0.99
175_T	190_G	0.724	0.99
183_F	187_I	0.724	0.99
180_F	191_R	0.723	0.99
434_T	441_E	0.720	0.99
124_M	127_A	0.720	0.99
130_L	323_V	0.720	0.99
115_Y	119_I	0.719	0.99
15_M	23_E	0.717	0.99
417_I	428_G	0.715	0.99
71_F	240_G	0.715	0.99
418_V	424_N	0.714	0.99
434_T	449_C	0.713	0.99
438_I	449_C	0.712	0.99
406_I	417_I	0.712	0.99
385_E	388_K	0.712	0.99
185_F	191_R	0.711	0.99
37_P	267_P	0.711	0.99
236_A	269_F	0.710	0.99
386_V	390_Q	0.706	0.99
107_I	118_L	0.706	0.99
301_L	305_I	0.705	0.99
122_L	324_K	0.704	0.99
182_V	191_R	0.704	0.99
179_I	191_R	0.704	0.99
251_P	254_L	0.704	0.99
13_G	216_A	0.703	0.99
422_Y	430_V	0.703	0.99
144_I	316_I	0.702	0.99
221_I	235_S	0.701	0.98
415_R	423_E	0.700	0.98
419_V	430_V	0.700	0.98
58_I	272_G	0.699	0.98
185_F	189_F	0.699	0.98
102_V	105_V	0.698	0.98
410_S	414_V	0.698	0.98
406_I	415_R	0.695	0.98
194_A	202_Y	0.694	0.98
185_F	188_M	0.694	0.98
420_V	430_V	0.693	0.98
384_Q	389_L	0.693	0.98
424_N	433_Q	0.691	0.98
418_V	423_E	0.689	0.98
87_N	150_Q	0.687	0.98
246_Y	249_D	0.686	0.98
147_L	312_I	0.685	0.98
412_R	426_P	0.684	0.98
442_L	447_K	0.684	0.98
404_S	408_K	0.683	0.98
110_I	345_M	0.682	0.98
424_N	431_S	0.681	0.98
391_I	394_L	0.681	0.98
418_V	428_G	0.680	0.98
431_S	435_L	0.680	0.98
71_F	218_I	0.679	0.98
399_E	405_V	0.679	0.98
440_P	444_E	0.676	0.98
437_E	441_E	0.676	0.98
398_C	401_N	0.675	0.98
316_I	367_N	0.675	0.98
95_E	99_P	0.673	0.98
250_R	254_L	0.672	0.98
22_S	28_R	0.668	0.98
142_N	145_S	0.668	0.98
307_S	312_I	0.668	0.98
397_S	401_N	0.667	0.98
420_V	424_N	0.667	0.98
18_A	22_S	0.666	0.98
406_I	420_V	0.666	0.98
190_G	198_E	0.665	0.98
410_S	417_I	0.664	0.98
420_V	437_E	0.663	0.98
85_N	88_V	0.662	0.98
254_L	257_L	0.662	0.98
422_Y	428_G	0.660	0.98
79_N	245_D	0.660	0.98
320_A	323_V	0.660	0.98
381_K	384_Q	0.660	0.98
366_I	371_S	0.660	0.98
420_V	428_G	0.660	0.98
217_I	220_I	0.659	0.98
248_K	252_E	0.658	0.98
411_E	432_I	0.656	0.98
189_F	197_L	0.651	0.98
189_F	221_I	0.650	0.98
379_K	382_L	0.650	0.98
402_L	409_I	0.649	0.98
133_M	320_A	0.649	0.98
359_I	363_L	0.645	0.97
410_S	415_R	0.645	0.97
284_I	348_F	0.642	0.97
18_A	44_L	0.641	0.97
440_P	448_A	0.641	0.97
147_L	150_Q	0.640	0.97
436_L	439_D	0.640	0.97
96_S	99_P	0.640	0.97
253_L	258_H	0.638	0.97
304_F	315_K	0.638	0.97
110_I	114_N	0.637	0.97
381_K	386_V	0.637	0.97
420_V	438_I	0.636	0.97
409_I	421_N	0.636	0.97
434_T	442_L	0.634	0.97
396_A	399_E	0.632	0.97
384_Q	387_I	0.632	0.97
417_I	421_N	0.630	0.97
408_K	412_R	0.628	0.97
183_F	191_R	0.628	0.97
127_A	148_I	0.623	0.97
423_E	442_L	0.623	0.97
95_E	303_G	0.622	0.97
319_F	363_L	0.622	0.97
90_L	310_L	0.621	0.97
127_A	275_L	0.621	0.97
410_S	426_P	0.621	0.97
91_A	306_S	0.618	0.97
182_V	201_E	0.618	0.97
175_T	197_L	0.616	0.97
285_I	332_L	0.615	0.97
172_I	180_F	0.613	0.97
390_Q	394_L	0.611	0.96
246_Y	253_L	0.610	0.96
125_S	321_T	0.610	0.96
214_L	241_I	0.609	0.96
372_N	376_E	0.609	0.96
397_S	400_E	0.608	0.96
151_Q	155_I	0.607	0.96
48_V	51_V	0.605	0.96
42_I	279_K	0.604	0.96
423_E	435_L	0.600	0.96
177_I	185_F	0.600	0.96
269_F	361_P	0.599	0.96
397_S	403_R	0.599	0.96
191_R	201_E	0.599	0.96
435_L	439_D	0.598	0.96
45_G	52_I	0.597	0.96
287_F	291_F	0.597	0.96
434_T	445_S	0.597	0.96
278_T	343_E	0.597	0.96
353_I	357_A	0.597	0.96
362_L	366_I	0.597	0.96
405_V	419_V	0.595	0.96
415_R	431_S	0.594	0.96
329_S	353_I	0.594	0.96
106_A	290_L	0.592	0.96
144_I	318_G	0.590	0.96
398_C	419_V	0.590	0.96
423_E	434_T	0.589	0.96
151_Q	317_N	0.589	0.96
326_G	329_S	0.589	0.96
408_K	415_R	0.588	0.96
24_E	28_R	0.587	0.96
373_K	376_E	0.585	0.95
405_V	411_E	0.584	0.95
409_I	414_V	0.582	0.95
438_I	441_E	0.581	0.95
175_T	191_R	0.578	0.95
121_P	349_S	0.578	0.95
369_K	374_I	0.578	0.95
191_R	242_L	0.577	0.95
438_I	446_T	0.577	0.95
78_F	245_D	0.576	0.95
378_K	382_L	0.575	0.95
23_E	28_R	0.574	0.95
411_E	423_E	0.574	0.95
299_K	321_T	0.573	0.95
408_K	411_E	0.573	0.95
411_E	417_I	0.573	0.95
421_N	430_V	0.572	0.95
178_E	193_L	0.572	0.95
395_Y	407_S	0.571	0.95
422_Y	429_Y	0.571	0.95
84_P	88_V	0.569	0.95
152_V	327_V	0.567	0.95
349_S	353_I	0.567	0.95
32_V	132_R	0.567	0.95
395_Y	409_I	0.566	0.95
172_I	182_V	0.564	0.94
417_I	427_L	0.563	0.94
400_E	404_S	0.562	0.94
156_E	231_N	0.559	0.94
88_V	150_Q	0.559	0.94
407_S	410_S	0.559	0.94
180_F	183_F	0.559	0.94
70_L	233_A	0.559	0.94
290_L	294_L	0.558	0.94
70_L	124_M	0.557	0.94
370_I	389_L	0.556	0.94
236_A	240_G	0.555	0.94
397_S	408_K	0.555	0.94
175_T	198_E	0.555	0.94
226_E	229_K	0.553	0.94
333_L	337_T	0.553	0.94
428_G	433_Q	0.553	0.94
19_A	354_S	0.553	0.94
65_G	269_F	0.552	0.94
131_S	149_F	0.552	0.94
281_N	343_E	0.550	0.94
412_R	423_E	0.549	0.94
160_V	330_S	0.549	0.94
283_S	287_F	0.549	0.94
303_G	318_G	0.546	0.93
195_K	201_E	0.546	0.93
189_F	224_L	0.545	0.93
427_L	432_I	0.543	0.93
421_N	424_N	0.542	0.93
426_P	443_Y	0.541	0.93
287_F	290_L	0.541	0.93
321_T	326_G	0.540	0.93
15_M	271_L	0.539	0.93
225_A	230_F	0.539	0.93
337_T	340_Y	0.538	0.93
70_L	237_F	0.537	0.93
436_L	444_E	0.537	0.93
418_V	433_Q	0.536	0.93
69_L	236_A	0.536	0.93
179_I	201_E	0.536	0.93
124_M	328_D	0.533	0.93
23_E	214_L	0.533	0.93
433_Q	443_Y	0.533	0.93
110_I	118_L	0.533	0.93
299_K	303_G	0.532	0.93
74_G	241_I	0.531	0.93
379_K	384_Q	0.530	0.92
420_V	432_I	0.528	0.92
250_R	253_L	0.528	0.92
149_F	329_S	0.528	0.92
325_G	329_S	0.528	0.92
126_S	152_V	0.527	0.92
19_A	22_S	0.526	0.92
395_Y	413_G	0.525	0.92
395_Y	421_N	0.524	0.92
436_L	448_A	0.524	0.92
86_A	89_F	0.523	0.92
395_Y	414_V	0.523	0.92
295_I	356_S	0.523	0.92
222_G	226_E	0.522	0.92
424_N	437_E	0.521	0.92
252_E	258_H	0.521	0.92
418_V	425_K	0.521	0.92
252_E	257_L	0.519	0.92
45_G	48_V	0.519	0.92
305_I	308_K	0.518	0.92
399_E	404_S	0.518	0.92
129_P	132_R	0.518	0.92
144_I	314_G	0.517	0.92
400_E	405_V	0.517	0.92
409_I	418_V	0.517	0.92
417_I	425_K	0.516	0.91
414_V	418_V	0.516	0.91
96_S	154_L	0.515	0.91
409_I	417_I	0.515	0.91
172_I	181_L	0.515	0.91
138_K	291_F	0.514	0.91
430_V	445_S	0.514	0.91
397_S	409_I	0.513	0.91
196_I	201_E	0.513	0.91
113_K	170_S	0.513	0.91
260_F	265_F	0.512	0.91
186_T	238_F	0.512	0.91
401_N	414_V	0.511	0.91
152_V	323_V	0.510	0.91
191_R	198_E	0.510	0.91
46_N	49_F	0.509	0.91
398_C	414_V	0.508	0.91
420_V	429_Y	0.506	0.91
401_N	417_I	0.505	0.91
408_K	418_V	0.502	0.90
401_N	407_S	0.501	0.90
117_I	170_S	0.501	0.90
404_S	412_R	0.500	0.90

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4bwzA	2	0.7327	100	0.424	Contact Map
4czbA	2	0.7366	100	0.447	Contact Map
4cz8A	2	0.7248	100	0.449	Contact Map
1zcdA	1	0.6733	99.9	0.705	Contact Map
4gx0A	3	0.4297	99.4	0.831	Contact Map
1lnqA	6	0.3782	99.1	0.855	Contact Map
3l9wA	2	0.2277	99	0.859	Contact Map
3nafA	3	0.2495	98.8	0.866	Contact Map
2aefA	2	0.2218	98.7	0.874	Contact Map
2mdfA	1	0.1129	98.7	0.875	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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