Q980D3 - SULSO - GREMLIN Contacts

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Q980D3 - Glutamine-fructose-6-phosphate transaminase (Isomerizing) (GlmS-1)

UniProt:	Q980D3	Sequences: MCGIIGIVSNKESNRLAELVVSCLNRLEYRGYDSVGVAALSGGNLEVRKAKGTVEEVVRKKNIKELSGYAFLGHTRWATHGAPTDYNAHPHTDCINNIAVIHNGTIRNFKELRDELQALGHKFKSETDTEVIPHMMEEYMKRGMDTFQAFRSAIKNIQGSYAVLAIVKGERRIFFAKRDNPLVIGLGDDKTFVASDIPSFLPYTRKVIVISDGELGYVTPNTVYMEDENGNPIDVTSRIKIIDWDASSASKQGYPHFMLKEIHESPIAVKDTISGLLSEVDKINEIAEEIRESSRIIVTAAGTSYHAGLYFSLLLTRKGYTVIPLIASEYHNFRARKGDIVLAISQSGETLDVKMGIRKFKDEGAKIIALTNVIESDIARESHYKLYMRAGPEIGVAATKTFTSEIVSLLFLYSLIEKESISYLETAHETVRNVITETEGFAKKIGEELANKNNVYYLGRGLGVPLAMEGALKIKEIAYIHAEAYPAGESKHGPIALVESGFPIIFVNDGELVDELEKNLQEMKARGGKTYSISVNKRLNFADTEILVNTSEKLSSLAIAPIIQLIAYYASVKRGYDPDKPRNLAKTVTVE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	591 (584)
Sequences:	3771 (2043)
Seq/√Len:	84.5

ECOLI - GLMS
BACSU - GLMS
HALSA - GLMS
SULSO - Q980D3 Q97YQ6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
115_E	156_N	4.930	1.00
119_L	138_E	4.359	1.00
294_S	338_G	4.179	1.00
227_D	231_N	4.078	1.00
369_A	382_S	4.005	1.00
269_V	431_V	3.859	1.00
25_N	58_V	3.687	1.00
150_F	174_F	3.459	1.00
298_V	308_G	3.457	1.00
145_D	148_Q	3.224	1.00
214_E	237_S	3.207	1.00
132_I	157_I	3.204	1.00
358_R	381_E	3.166	1.00
398_A	401_T	3.128	1.00
20_V	71_F	3.121	1.00
267_I	271_D	3.057	1.00
136_M	153_A	2.999	1.00
53_T	580_K	2.988	1.00
432_R	436_T	2.906	1.00
439_E	569_Y	2.900	1.00
121_H	137_E	2.812	1.00
269_V	407_V	2.714	1.00
50_A	60_K	2.712	1.00
206_K	241_I	2.699	1.00
97_N	169_G	2.688	1.00
175_F	193_V	2.610	1.00
172_R	217_Y	2.578	1.00
532_S	542_A	2.575	1.00
147_F	226_E	2.527	1.00
121_H	138_E	2.497	1.00
175_F	216_G	2.467	1.00
344_I	409_L	2.448	1.00
132_I	163_V	2.412	1.00
431_V	561_P	2.387	1.00
139_Y	156_N	2.359	1.00
100_V	133_P	2.331	1.00
121_H	134_H	2.287	1.00
184_I	223_V	2.276	1.00
294_S	336_R	2.239	1.00
146_T	174_F	2.235	1.00
224_Y	232_P	2.231	1.00
55_E	59_R	2.229	1.00
86_Y	126_E	2.207	1.00
184_I	216_G	2.201	1.00
50_A	85_D	2.151	1.00
524_K	543_D	2.150	1.00
448_E	544_T	2.145	1.00
186_L	208_I	2.133	1.00
471_A	482_A	2.112	1.00
136_M	165_A	2.105	1.00
427_A	557_L	2.091	1.00
187_G	190_K	2.081	1.00
308_G	344_I	2.058	1.00
315_L	416_I	2.043	1.00
263_H	439_E	2.039	1.00
22_S	202_P	2.011	1.00
315_L	322_V	1.999	1.00
113_R	117_Q	1.987	1.00
572_V	578_P	1.953	1.00
146_T	167_V	1.933	1.00
272_T	388_M	1.925	1.00
315_L	413_Y	1.924	1.00
191_T	223_V	1.916	1.00
506_F	520_L	1.900	1.00
487_A	516_L	1.899	1.00
158_Q	514_D	1.869	1.00
100_V	129_T	1.864	1.00
343_A	357_I	1.850	1.00
295_R	323_I	1.837	1.00
164_L	193_V	1.837	1.00
326_I	486_P	1.829	1.00
147_F	217_Y	1.828	1.00
93_D	121_H	1.824	1.00
402_F	466_L	1.824	1.00
164_L	173_I	1.819	1.00
154_I	157_I	1.815	1.00
139_Y	152_S	1.813	1.00
60_K	85_D	1.802	1.00
39_A	68_G	1.789	1.00
450_A	573_K	1.779	1.00
171_R	220_P	1.767	1.00
150_F	165_A	1.762	1.00
359_K	362_D	1.761	1.00
92_T	99_A	1.761	1.00
56_E	59_R	1.758	1.00
434_V	558_A	1.757	1.00
139_Y	153_A	1.755	1.00
97_N	168_K	1.747	1.00
468_M	484_A	1.746	1.00
325_L	333_F	1.745	1.00
206_K	239_I	1.740	1.00
505_I	566_I	1.736	1.00
186_L	223_V	1.733	1.00
303_T	398_A	1.730	1.00
11_K	190_K	1.729	1.00
49_K	85_D	1.729	1.00
211_S	237_S	1.725	1.00
136_M	150_F	1.710	1.00
470_G	563_I	1.706	1.00
51_K	84_T	1.700	1.00
335_A	365_A	1.694	1.00
217_Y	224_Y	1.668	1.00
45_L	99_A	1.658	1.00
53_T	577_D	1.653	1.00
447_E	573_K	1.652	1.00
336_R	339_D	1.652	1.00
423_Y	551_S	1.649	1.00
305_Y	309_L	1.646	1.00
423_Y	430_T	1.641	1.00
433_N	536_N	1.640	1.00
186_L	191_T	1.640	1.00
341_V	365_A	1.638	1.00
20_V	73_G	1.632	1.00
205_R	241_I	1.632	1.00
319_G	334_R	1.618	1.00
317_R	334_R	1.613	1.00
148_Q	151_R	1.607	1.00
367_I	382_S	1.603	1.00
268_A	404_S	1.597	1.00
8_V	70_A	1.597	1.00
114_D	118_A	1.589	1.00
547_L	559_I	1.588	1.00
537_K	549_N	1.584	1.00
98_I	140_M	1.577	1.00
172_R	219_T	1.577	1.00
38_A	99_A	1.574	1.00
153_A	157_I	1.572	1.00
8_V	220_P	1.567	1.00
191_T	222_T	1.564	1.00
440_G	443_K	1.562	1.00
293_S	340_I	1.557	1.00
98_I	167_V	1.550	1.00
175_F	184_I	1.535	1.00
254_Y	263_H	1.528	1.00
225_M	237_S	1.527	1.00
371_T	379_A	1.524	1.00
17_A	37_V	1.524	1.00
426_T	430_T	1.518	1.00
433_N	436_T	1.516	1.00
140_M	144_M	1.515	1.00
388_M	404_S	1.505	0.99
345_S	378_I	1.503	0.99
21_V	37_V	1.501	0.99
569_Y	573_K	1.501	0.99
109_F	113_R	1.494	0.99
111_E	158_Q	1.482	0.99
458_L	523_M	1.474	0.99
48_R	60_K	1.467	0.99
93_D	137_E	1.458	0.99
219_T	222_T	1.456	0.99
256_H	568_Y	1.455	0.99
208_I	223_V	1.454	0.99
178_R	213_G	1.431	0.99
154_I	176_A	1.422	0.99
330_Y	335_A	1.417	0.99
100_V	132_I	1.406	0.99
92_T	96_N	1.406	0.99
374_I	387_Y	1.403	0.99
22_S	25_N	1.402	0.99
41_S	44_N	1.401	0.99
449_L	544_T	1.398	0.99
55_E	58_V	1.396	0.99
98_I	146_T	1.391	0.99
38_A	45_L	1.381	0.99
296_I	342_L	1.375	0.99
197_I	209_V	1.364	0.99
361_K	383_H	1.352	0.99
464_V	468_M	1.350	0.99
458_L	506_F	1.334	0.99
354_K	358_R	1.327	0.99
430_T	550_T	1.326	0.99
140_M	167_V	1.326	0.99
255_P	572_V	1.323	0.99
379_A	385_K	1.318	0.99
534_S	545_E	1.316	0.99
415_L	419_E	1.314	0.99
151_R	226_E	1.314	0.99
9_S	16_L	1.307	0.99
466_L	560_A	1.299	0.98
297_I	330_Y	1.298	0.98
312_S	323_I	1.295	0.98
51_K	83_P	1.293	0.98
520_L	530_T	1.284	0.98
114_D	117_Q	1.280	0.98
270_K	432_R	1.280	0.98
147_F	151_R	1.276	0.98
40_L	166_I	1.275	0.98
7_I	16_L	1.274	0.98
149_A	153_A	1.261	0.98
113_R	123_F	1.260	0.98
289_E	366_K	1.253	0.98
314_L	410_L	1.241	0.98
351_L	355_M	1.226	0.98
370_L	409_L	1.226	0.98
369_A	378_I	1.225	0.98
445_I	531_Y	1.224	0.98
208_I	225_M	1.224	0.98
210_I	216_G	1.221	0.98
438_T	441_F	1.219	0.98
38_A	47_V	1.216	0.98
513_V	538_R	1.210	0.98
357_I	378_I	1.209	0.98
449_L	566_I	1.202	0.97
429_E	432_R	1.193	0.97
217_Y	226_E	1.191	0.97
342_L	412_L	1.181	0.97
165_A	174_F	1.178	0.97
453_N	574_R	1.177	0.97
97_N	137_E	1.172	0.97
341_V	360_F	1.170	0.97
272_T	408_S	1.170	0.97
550_T	558_A	1.168	0.97
115_E	138_E	1.163	0.97
533_I	547_L	1.158	0.97
566_I	570_A	1.155	0.97
138_E	142_R	1.152	0.97
439_E	443_K	1.152	0.97
139_Y	142_R	1.147	0.97
458_L	490_S	1.145	0.97
259_L	263_H	1.145	0.97
386_L	408_S	1.144	0.97
265_S	403_T	1.138	0.96
498_V	528_G	1.137	0.96
296_I	340_I	1.137	0.96
226_E	232_P	1.128	0.96
140_M	143_G	1.127	0.96
123_F	131_V	1.127	0.96
461_G	512_L	1.126	0.96
187_G	191_T	1.123	0.96
295_R	336_R	1.123	0.96
113_R	131_V	1.122	0.96
311_F	409_L	1.121	0.96
51_K	56_E	1.121	0.96
70_A	173_I	1.120	0.96
21_V	58_V	1.119	0.96
147_F	215_L	1.117	0.96
571_S	576_Y	1.115	0.96
430_T	558_A	1.113	0.96
140_M	169_G	1.105	0.96
251_K	580_K	1.102	0.96
97_N	167_V	1.101	0.96
244_W	249_A	1.099	0.96
448_E	529_K	1.095	0.96
174_F	217_Y	1.094	0.96
152_S	155_K	1.094	0.96
44_N	168_K	1.092	0.95
146_T	150_F	1.090	0.95
388_M	405_E	1.088	0.95
110_K	114_D	1.087	0.95
508_N	559_I	1.083	0.95
510_G	552_E	1.079	0.95
295_R	321_T	1.072	0.95
6_G	193_V	1.072	0.95
343_A	367_I	1.070	0.95
339_D	365_A	1.069	0.95
455_V	505_I	1.067	0.95
186_L	239_I	1.058	0.95
17_A	68_G	1.055	0.95
434_V	438_T	1.055	0.95
331_H	355_M	1.054	0.95
443_K	447_E	1.052	0.94
40_L	70_A	1.050	0.94
534_S	538_R	1.047	0.94
48_R	65_E	1.045	0.94
366_K	383_H	1.044	0.94
438_T	442_A	1.044	0.94
306_H	309_L	1.044	0.94
577_D	580_K	1.043	0.94
185_G	204_T	1.042	0.94
343_A	382_S	1.041	0.94
366_K	384_Y	1.037	0.94
148_Q	152_S	1.036	0.94
504_I	528_G	1.030	0.94
521_Q	524_K	1.030	0.94
296_I	320_Y	1.030	0.94
318_K	413_Y	1.028	0.94
431_V	557_L	1.022	0.94
441_F	444_K	1.022	0.94
161_Y	178_R	1.021	0.94
535_V	549_N	1.020	0.94
136_M	149_A	1.020	0.94
277_L	425_E	1.018	0.93
427_A	558_A	1.011	0.93
565_L	569_Y	1.011	0.93
191_T	221_N	1.007	0.93
51_K	82_A	1.001	0.93
10_N	220_P	0.994	0.93
255_P	259_L	0.990	0.92
164_L	175_F	0.988	0.92
82_A	527_G	0.988	0.92
444_K	447_E	0.984	0.92
256_H	259_L	0.984	0.92
415_L	418_K	0.983	0.92
311_F	315_L	0.983	0.92
259_L	439_E	0.982	0.92
423_Y	426_T	0.982	0.92
407_V	557_L	0.980	0.92
523_M	530_T	0.976	0.92
446_G	566_I	0.975	0.92
316_T	333_F	0.975	0.92
279_E	425_E	0.973	0.92
193_V	218_V	0.971	0.92
117_Q	122_K	0.967	0.92
49_K	92_T	0.966	0.92
93_D	96_N	0.964	0.91
17_A	39_A	0.964	0.91
343_A	360_F	0.962	0.91
310_Y	466_L	0.962	0.91
306_H	468_M	0.961	0.91
276_L	411_F	0.960	0.91
507_V	563_I	0.959	0.91
140_M	145_D	0.956	0.91
490_S	495_I	0.956	0.91
296_I	322_V	0.954	0.91
463_G	507_V	0.952	0.91
354_K	377_D	0.951	0.91
93_D	97_N	0.950	0.91
359_K	363_E	0.950	0.91
529_K	543_D	0.948	0.91
523_M	528_G	0.947	0.91
151_R	215_L	0.946	0.91
284_N	287_A	0.945	0.91
82_A	126_E	0.943	0.91
267_I	432_R	0.941	0.90
164_L	218_V	0.940	0.90
166_I	173_I	0.936	0.90
297_I	339_D	0.936	0.90
209_V	240_K	0.933	0.90
25_N	54_V	0.929	0.90
298_V	322_V	0.928	0.90
139_Y	149_A	0.927	0.90
320_Y	420_S	0.927	0.90
198_P	201_L	0.925	0.90
240_K	375_E	0.924	0.90
99_A	166_I	0.923	0.90
390_A	404_S	0.918	0.89
315_L	412_L	0.917	0.89
86_Y	124_K	0.917	0.89
70_A	171_R	0.916	0.89
395_G	401_T	0.915	0.89
177_K	212_D	0.913	0.89
188_D	206_K	0.913	0.89
51_K	85_D	0.911	0.89
47_V	92_T	0.911	0.89
41_S	46_E	0.910	0.89
177_K	358_R	0.906	0.89
379_A	387_Y	0.906	0.89
132_I	153_A	0.905	0.89
411_F	421_I	0.904	0.89
98_I	133_P	0.900	0.88
454_N	502_F	0.894	0.88
293_S	366_K	0.893	0.88
456_Y	502_F	0.893	0.88
273_I	424_L	0.892	0.88
443_K	569_Y	0.891	0.88
292_E	338_G	0.890	0.88
216_G	223_V	0.889	0.88
11_K	192_F	0.889	0.88
116_L	123_F	0.889	0.88
402_F	465_P	0.889	0.88
454_N	481_H	0.888	0.88
134_H	137_E	0.886	0.88
54_V	61_K	0.886	0.88
126_E	521_Q	0.881	0.87
53_T	251_K	0.880	0.87
115_E	119_L	0.879	0.87
256_H	572_V	0.878	0.87
423_Y	554_L	0.877	0.87
146_T	165_A	0.877	0.87
95_I	137_E	0.874	0.87
147_F	224_Y	0.873	0.87
50_A	56_E	0.871	0.87
160_S	179_D	0.869	0.87
474_I	480_I	0.869	0.87
426_T	429_E	0.867	0.86
26_R	202_P	0.866	0.86
298_V	324_P	0.866	0.86
258_M	395_G	0.865	0.86
498_V	504_I	0.863	0.86
21_V	61_K	0.863	0.86
204_T	241_I	0.862	0.86
389_R	392_P	0.858	0.86
457_Y	474_I	0.858	0.86
208_I	239_I	0.858	0.86
161_Y	228_E	0.858	0.86
8_V	171_R	0.856	0.86
39_A	66_L	0.854	0.86
457_Y	563_I	0.849	0.85
263_H	435_I	0.847	0.85
298_V	409_L	0.847	0.85
12_E	69_Y	0.842	0.85
309_L	324_P	0.841	0.85
521_Q	541_F	0.839	0.85
300_A	304_S	0.839	0.85
295_R	339_D	0.839	0.85
294_S	339_D	0.838	0.85
39_A	71_F	0.838	0.85
536_N	549_N	0.836	0.84
515_E	591_E	0.834	0.84
250_S	257_F	0.831	0.84
519_N	522_E	0.830	0.84
558_A	562_I	0.830	0.84
95_I	141_K	0.829	0.84
54_V	73_G	0.829	0.84
311_F	413_Y	0.829	0.84
132_I	154_I	0.826	0.84
465_P	494_P	0.825	0.84
184_I	210_I	0.825	0.84
124_K	134_H	0.824	0.84
144_M	148_Q	0.821	0.83
107_R	515_E	0.816	0.83
438_T	546_I	0.813	0.83
357_I	382_S	0.812	0.83
58_V	62_N	0.810	0.82
137_E	141_K	0.808	0.82
534_S	539_L	0.808	0.82
225_M	233_I	0.808	0.82
190_K	204_T	0.807	0.82
175_F	210_I	0.806	0.82
453_N	499_E	0.806	0.82
299_T	330_Y	0.805	0.82
140_M	149_A	0.803	0.82
134_H	138_E	0.800	0.82
173_I	193_V	0.800	0.82
145_D	172_R	0.799	0.82
395_G	494_P	0.799	0.82
242_I	375_E	0.797	0.81
474_I	478_A	0.796	0.81
312_S	316_T	0.795	0.81
299_T	341_V	0.793	0.81
499_E	528_G	0.792	0.81
194_A	199_S	0.790	0.81
59_R	63_I	0.788	0.81
61_K	65_E	0.787	0.81
506_F	516_L	0.785	0.80
449_L	455_V	0.782	0.80
49_K	86_Y	0.781	0.80
455_V	474_I	0.781	0.80
19_L	203_Y	0.779	0.80
286_I	289_E	0.778	0.80
467_A	507_V	0.774	0.80
259_L	568_Y	0.774	0.80
465_P	484_A	0.772	0.79
193_V	216_G	0.770	0.79
70_A	166_I	0.768	0.79
430_T	434_V	0.767	0.79
402_F	560_A	0.767	0.79
463_G	555_S	0.766	0.79
191_T	218_V	0.766	0.79
529_K	544_T	0.766	0.79
298_V	342_L	0.766	0.79
307_A	409_L	0.764	0.79
309_L	468_M	0.764	0.79
403_T	561_P	0.764	0.79
215_L	226_E	0.763	0.79
287_A	290_I	0.762	0.78
458_L	467_A	0.761	0.78
303_T	307_A	0.761	0.78
184_I	208_I	0.761	0.78
470_G	477_I	0.760	0.78
470_G	560_A	0.760	0.78
542_A	545_E	0.759	0.78
163_V	176_A	0.758	0.78
167_V	174_F	0.757	0.78
327_A	523_M	0.756	0.78
123_F	135_M	0.755	0.78
254_Y	259_L	0.753	0.78
48_R	64_K	0.753	0.78
374_I	385_K	0.752	0.78
449_L	505_I	0.752	0.78
227_D	233_I	0.751	0.77
7_I	19_L	0.748	0.77
471_A	484_A	0.748	0.77
45_L	92_T	0.748	0.77
142_R	152_S	0.748	0.77
281_D	284_N	0.747	0.77
422_S	426_T	0.746	0.77
370_L	388_M	0.743	0.77
272_T	404_S	0.743	0.77
141_K	149_A	0.743	0.77
395_G	402_F	0.742	0.77
197_I	201_L	0.742	0.77
293_S	339_D	0.740	0.76
335_A	339_D	0.738	0.76
570_A	574_R	0.738	0.76
511_E	552_E	0.736	0.76
334_R	363_E	0.735	0.76
280_V	386_L	0.734	0.76
184_I	225_M	0.733	0.76
442_A	565_L	0.733	0.76
369_A	385_K	0.732	0.76
7_I	190_K	0.732	0.76
314_L	413_Y	0.731	0.76
20_V	37_V	0.730	0.75
143_G	148_Q	0.730	0.75
47_V	99_A	0.730	0.75
557_L	562_I	0.729	0.75
442_A	566_I	0.728	0.75
98_I	169_G	0.724	0.75
115_E	118_A	0.724	0.75
534_S	537_K	0.723	0.75
485_Y	494_P	0.722	0.75
11_K	19_L	0.721	0.75
291_R	419_E	0.720	0.74
259_L	569_Y	0.719	0.74
314_L	406_I	0.718	0.74
305_Y	326_I	0.717	0.74
96_N	137_E	0.716	0.74
361_K	381_E	0.716	0.74
374_I	379_A	0.715	0.74
12_E	17_A	0.715	0.74
171_R	219_T	0.715	0.74
340_I	368_I	0.715	0.74
430_T	433_N	0.714	0.74
200_F	207_V	0.714	0.74
147_F	174_F	0.712	0.74
205_R	245_D	0.712	0.74
259_L	565_L	0.711	0.73
59_R	62_N	0.710	0.73
230_G	233_I	0.710	0.73
210_I	214_E	0.709	0.73
82_A	86_Y	0.709	0.73
158_Q	178_R	0.708	0.73
414_S	417_E	0.706	0.73
360_F	365_A	0.706	0.73
406_I	557_L	0.705	0.73
343_A	353_V	0.705	0.73
114_D	540_N	0.704	0.73
386_L	412_L	0.702	0.73
214_E	227_D	0.700	0.72
319_G	322_V	0.700	0.72
12_E	18_E	0.700	0.72
303_T	496_A	0.700	0.72
445_I	449_L	0.699	0.72
311_F	314_L	0.698	0.72
500_S	527_G	0.698	0.72
152_S	156_N	0.697	0.72
370_L	412_L	0.697	0.72
343_A	369_A	0.697	0.72
6_G	164_L	0.695	0.72
449_L	570_A	0.695	0.72
509_D	538_R	0.695	0.72
509_D	513_V	0.694	0.72
401_T	587_T	0.694	0.72
101_I	183_V	0.693	0.72
227_D	230_G	0.691	0.71
50_A	54_V	0.689	0.71
318_K	420_S	0.688	0.71
312_S	324_P	0.687	0.71
17_A	66_L	0.686	0.71
571_S	578_P	0.685	0.71
452_K	529_K	0.685	0.71
8_V	218_V	0.683	0.70
280_V	283_I	0.682	0.70
138_E	141_K	0.681	0.70
35_V	57_V	0.681	0.70
172_R	175_F	0.678	0.70
422_S	425_E	0.676	0.70
211_S	214_E	0.676	0.70
268_A	272_T	0.674	0.69
413_Y	417_E	0.673	0.69
269_V	388_M	0.672	0.69
116_L	135_M	0.672	0.69
456_Y	499_E	0.672	0.69
403_T	557_L	0.671	0.69
244_W	375_E	0.671	0.69
407_V	424_L	0.670	0.69
105_T	518_K	0.668	0.69
315_L	318_K	0.668	0.69
455_V	570_A	0.667	0.69
201_L	204_T	0.667	0.69
202_P	205_R	0.666	0.69
412_L	416_I	0.666	0.69
97_N	140_M	0.666	0.69
10_N	189_D	0.666	0.69
456_Y	578_P	0.665	0.68
398_A	496_A	0.664	0.68
201_L	244_W	0.664	0.68
151_R	230_G	0.664	0.68
268_A	390_A	0.662	0.68
268_A	280_V	0.659	0.68
116_L	120_G	0.658	0.68
192_F	203_Y	0.653	0.67
478_A	576_Y	0.650	0.67
183_V	354_K	0.649	0.67
18_E	58_V	0.648	0.66
189_D	221_N	0.648	0.66
12_E	67_S	0.647	0.66
273_I	407_V	0.646	0.66
406_I	410_L	0.646	0.66
490_S	523_M	0.645	0.66
49_K	124_K	0.644	0.66
421_I	425_E	0.644	0.66
358_R	377_D	0.644	0.66
443_K	573_K	0.644	0.66
342_L	368_I	0.643	0.66
24_L	35_V	0.642	0.66
242_I	249_A	0.641	0.66
309_L	461_G	0.641	0.66
446_G	573_K	0.640	0.65
212_D	358_R	0.636	0.65
331_H	515_E	0.635	0.65
230_G	234_D	0.635	0.65
151_R	155_K	0.633	0.65
434_V	547_L	0.633	0.65
258_M	477_I	0.633	0.65
26_R	250_S	0.632	0.65
284_N	290_I	0.632	0.65
179_D	510_G	0.631	0.64
402_F	494_P	0.631	0.64
550_T	554_L	0.630	0.64
442_A	562_I	0.629	0.64
441_F	544_T	0.628	0.64
403_T	560_A	0.625	0.64
1_M	4_I	0.625	0.64
407_V	427_A	0.620	0.63
37_V	73_G	0.619	0.63
510_G	549_N	0.619	0.63
182_L	193_V	0.619	0.63
456_Y	498_V	0.618	0.63
254_Y	439_E	0.618	0.63
287_A	291_R	0.618	0.63
180_N	351_L	0.616	0.63
100_V	163_V	0.616	0.63
328_S	488_G	0.615	0.62
92_T	134_H	0.615	0.62
275_G	389_R	0.615	0.62
69_Y	220_P	0.615	0.62
96_N	124_K	0.614	0.62
463_G	559_I	0.614	0.62
450_A	570_A	0.614	0.62
142_R	145_D	0.614	0.62
132_I	165_A	0.613	0.62
535_V	555_S	0.612	0.62
12_E	16_L	0.612	0.62
283_I	287_A	0.612	0.62
72_L	164_L	0.611	0.62
452_K	503_P	0.611	0.62
6_G	364_G	0.609	0.62
434_V	442_A	0.609	0.62
304_S	344_I	0.608	0.62
113_R	133_P	0.607	0.61
465_P	468_M	0.607	0.61
402_F	463_G	0.606	0.61
507_V	559_I	0.605	0.61
110_K	113_R	0.605	0.61
306_H	371_T	0.605	0.61
451_N	574_R	0.605	0.61
93_D	398_A	0.604	0.61
457_Y	487_A	0.604	0.61
455_V	482_A	0.604	0.61
283_I	286_I	0.603	0.61
183_V	197_I	0.603	0.61
271_D	388_M	0.602	0.61
378_I	387_Y	0.602	0.61
377_D	381_E	0.602	0.61
139_Y	144_M	0.602	0.61
449_L	532_S	0.601	0.61
299_T	343_A	0.601	0.61
454_N	485_Y	0.601	0.61
183_V	200_F	0.600	0.61
326_I	488_G	0.600	0.61
245_D	248_S	0.600	0.61
269_V	434_V	0.599	0.60
98_I	149_A	0.598	0.60
343_A	378_I	0.598	0.60
457_Y	567_A	0.597	0.60
84_T	88_A	0.597	0.60
184_I	193_V	0.596	0.60
150_F	153_A	0.596	0.60
233_I	237_S	0.596	0.60
495_I	498_V	0.593	0.60
192_F	200_F	0.593	0.60
98_I	137_E	0.590	0.59
234_D	238_R	0.590	0.59
378_I	382_S	0.589	0.59
102_H	180_N	0.589	0.59
463_G	510_G	0.589	0.59
210_I	290_I	0.587	0.59
495_I	528_G	0.586	0.59
16_L	19_L	0.584	0.58
8_V	173_I	0.584	0.58
157_I	161_Y	0.584	0.58
423_Y	427_A	0.584	0.58
300_A	324_P	0.584	0.58
24_L	73_G	0.581	0.58
405_E	409_L	0.581	0.58
296_I	315_L	0.578	0.58
18_E	22_S	0.578	0.58
135_M	157_I	0.578	0.58
533_I	563_I	0.577	0.58
123_F	134_H	0.577	0.58
375_E	379_A	0.576	0.57
398_A	528_G	0.575	0.57
465_P	471_A	0.575	0.57
140_M	146_T	0.575	0.57
48_R	61_K	0.575	0.57
326_I	490_S	0.574	0.57
585_A	589_T	0.573	0.57
109_F	521_Q	0.573	0.57
209_V	395_G	0.573	0.57
219_T	223_V	0.573	0.57
299_T	360_F	0.572	0.57
532_S	545_E	0.572	0.57
97_N	141_K	0.571	0.57
394_I	580_K	0.571	0.57
201_L	205_R	0.570	0.57
361_K	367_I	0.570	0.57
244_W	374_I	0.569	0.57
494_P	507_V	0.569	0.57
334_R	511_E	0.568	0.56
37_V	61_K	0.567	0.56
179_D	212_D	0.566	0.56
533_I	559_I	0.564	0.56
186_L	221_N	0.564	0.56
455_V	480_I	0.563	0.56
180_N	523_M	0.563	0.56
6_G	486_P	0.563	0.56
257_F	374_I	0.563	0.56
277_L	421_I	0.562	0.56
495_I	499_E	0.561	0.55
455_V	502_F	0.561	0.55
297_I	336_R	0.560	0.55
200_F	247_S	0.559	0.55
411_F	414_S	0.558	0.55
298_V	315_L	0.557	0.55
107_R	355_M	0.557	0.55
10_N	69_Y	0.557	0.55
494_P	567_A	0.556	0.55
579_D	586_K	0.556	0.55
272_T	370_L	0.556	0.55
310_Y	556_S	0.556	0.55
147_F	172_R	0.556	0.55
453_N	501_G	0.556	0.55
183_V	198_P	0.555	0.55
427_A	554_L	0.555	0.55
355_M	518_K	0.554	0.55
265_S	561_P	0.554	0.55
524_K	530_T	0.553	0.54
313_L	465_P	0.553	0.54
150_F	154_I	0.552	0.54
197_I	207_V	0.552	0.54
118_A	188_D	0.551	0.54
115_E	139_Y	0.551	0.54
92_T	168_K	0.551	0.54
376_S	379_A	0.550	0.54
306_H	405_E	0.550	0.54
474_I	570_A	0.549	0.54
456_Y	528_G	0.549	0.54
45_L	166_I	0.549	0.54
414_S	418_K	0.549	0.54
560_A	563_I	0.549	0.54
501_G	527_G	0.548	0.54
176_A	213_G	0.548	0.54
297_I	323_I	0.547	0.54
367_I	383_H	0.547	0.54
581_P	586_K	0.547	0.54
547_L	558_A	0.547	0.54
480_I	570_A	0.546	0.53
117_Q	126_E	0.545	0.53
162_A	373_V	0.545	0.53
205_R	375_E	0.545	0.53
288_E	292_E	0.545	0.53
339_D	344_I	0.545	0.53
98_I	165_A	0.543	0.53
402_F	456_Y	0.543	0.53
189_D	192_F	0.541	0.53
558_A	561_P	0.541	0.53
73_G	345_S	0.541	0.53
85_D	88_A	0.540	0.53
186_L	206_K	0.539	0.53
474_I	556_S	0.539	0.53
516_L	520_L	0.539	0.53
112_L	157_I	0.539	0.53
219_T	224_Y	0.539	0.53
515_E	518_K	0.539	0.53
19_L	192_F	0.538	0.52
375_E	387_Y	0.537	0.52
204_T	239_I	0.537	0.52
283_I	386_L	0.536	0.52
44_N	122_K	0.536	0.52
398_A	498_V	0.536	0.52
530_T	542_A	0.535	0.52
551_S	554_L	0.535	0.52
229_N	232_P	0.535	0.52
375_E	385_K	0.534	0.52
316_T	324_P	0.534	0.52
306_H	567_A	0.534	0.52
290_I	293_S	0.533	0.52
520_L	532_S	0.533	0.52
74_H	89_H	0.533	0.52
198_P	375_E	0.532	0.52
20_V	39_A	0.531	0.51
401_T	498_V	0.531	0.51
332_N	355_M	0.530	0.51
57_V	515_E	0.530	0.51
410_L	554_L	0.529	0.51
521_Q	525_A	0.528	0.51
465_P	482_A	0.528	0.51
5_I	27_L	0.527	0.51
268_A	550_T	0.527	0.51
256_H	576_Y	0.526	0.51
463_G	509_D	0.526	0.51
150_F	176_A	0.526	0.51
357_I	367_I	0.526	0.51
214_E	233_I	0.526	0.51
426_T	550_T	0.526	0.51
292_E	366_K	0.525	0.51
182_L	210_I	0.525	0.51
93_D	134_H	0.525	0.51
289_E	293_S	0.524	0.51
177_K	375_E	0.522	0.50
373_V	388_M	0.522	0.50
144_M	152_S	0.522	0.50
524_K	542_A	0.521	0.50
134_H	139_Y	0.521	0.50
160_S	180_N	0.521	0.50
17_A	21_V	0.521	0.50
43_G	171_R	0.520	0.50
270_K	428_H	0.520	0.50
11_K	203_Y	0.519	0.50
29_Y	196_D	0.519	0.50
172_R	311_F	0.519	0.50
182_L	383_H	0.517	0.50
303_T	494_P	0.516	0.49
310_Y	313_L	0.516	0.49
533_I	546_I	0.516	0.49
332_N	518_K	0.516	0.49
93_D	116_L	0.515	0.49
178_R	228_E	0.515	0.49
223_V	239_I	0.515	0.49
520_L	542_A	0.514	0.49
180_N	212_D	0.514	0.49
434_V	562_I	0.514	0.49
431_V	435_I	0.514	0.49
292_E	337_K	0.514	0.49
16_L	71_F	0.514	0.49
79_T	91_H	0.513	0.49
247_S	255_P	0.513	0.49
304_S	490_S	0.512	0.49
8_V	172_R	0.512	0.49
136_M	163_V	0.512	0.49
364_G	375_E	0.512	0.49
434_V	548_V	0.512	0.49
471_A	480_I	0.512	0.49
190_K	333_F	0.510	0.49
509_D	535_V	0.510	0.49
196_D	587_T	0.509	0.49
504_I	523_M	0.508	0.48
298_V	514_D	0.507	0.48
26_R	246_A	0.507	0.48
470_G	507_V	0.507	0.48
370_L	408_S	0.507	0.48
447_E	450_A	0.507	0.48
209_V	379_A	0.505	0.48
255_P	443_K	0.505	0.48
499_E	521_Q	0.505	0.48
458_L	516_L	0.505	0.48
9_S	19_L	0.505	0.48
273_I	555_S	0.505	0.48
289_E	292_E	0.505	0.48
6_G	477_I	0.504	0.48
395_G	496_A	0.504	0.48
510_G	555_S	0.503	0.48
474_I	566_I	0.502	0.48
471_A	496_A	0.502	0.48
304_S	401_T	0.501	0.47
556_S	562_I	0.501	0.47
245_D	375_E	0.501	0.47
304_S	371_T	0.501	0.47
187_G	204_T	0.501	0.47
304_S	324_P	0.501	0.47
7_I	11_K	0.500	0.47
91_H	125_S	0.500	0.47
498_V	523_M	0.500	0.47
255_P	580_K	0.500	0.47

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4amvA	2	0.9848	100	0.333	Contact Map
2zj3A	2	0.577	100	0.593	Contact Map
3tbfA	2	0.5635	100	0.6	Contact Map
4s1wA	2	0.5567	100	0.601	Contact Map
1moqA	2	0.5787	100	0.602	Contact Map
2pocA	4	0.5533	100	0.602	Contact Map
1j5xA	2	0.5296	100	0.639	Contact Map
3knzA	2	0.5178	100	0.649	Contact Map
3fj1A	2	0.5482	100	0.649	Contact Map
2amlA	2	0.577	100	0.651	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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