GREMLIN Database
Q980B9 - Uncharacterized protein
UniProt: Q980B9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 572 (449)
Sequences: 1252 (988)
Seq/√Len: 46.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
231_K235_K7.3781.00
202_A205_V4.6671.00
485_V490_V4.6251.00
483_A501_N4.1981.00
286_H484_E3.8161.00
268_A495_I3.7531.00
232_Y235_K3.6861.00
287_G423_D3.4801.00
267_L513_F3.3831.00
261_G486_R3.3531.00
397_I400_L3.3281.00
230_T235_K3.2791.00
286_H487_K3.2281.00
176_F179_N3.0511.00
256_I268_A2.9741.00
254_I493_I2.9041.00
251_N260_S2.8831.00
515_F553_V2.7581.00
368_R406_S2.7191.00
200_L205_V2.7061.00
201_S205_V2.6361.00
346_T373_M2.6051.00
396_Y400_L2.5991.00
201_S204_S2.5791.00
174_L180_D2.4951.00
174_L179_N2.4911.00
265_S269_K2.4871.00
195_F205_V2.4371.00
208_K211_E2.4331.00
256_I267_L2.4281.00
341_N398_Q2.4201.00
479_E483_A2.3841.00
230_T233_G2.3261.00
279_S456_L2.3171.00
198_T202_A2.2511.00
346_T370_V2.2371.00
270_S274_K2.2351.00
210_I213_G2.2281.00
462_I478_V2.2151.00
221_P225_N2.2101.00
206_N211_E2.1841.00
200_L203_Y2.1681.00
467_F484_E2.1561.00
482_F492_M2.1501.00
195_F204_S2.1361.00
307_L370_V2.1341.00
207_E210_I2.1201.00
208_K215_I2.0260.99
265_S288_E2.0200.99
210_I217_G1.9630.99
345_D373_M1.9420.99
211_E217_G1.9220.99
174_L183_F1.8870.99
139_N145_L1.8590.99
207_E211_E1.8400.99
269_K288_E1.8090.99
253_N260_S1.8020.99
466_P483_A1.7810.99
209_G213_G1.7810.99
484_E488_F1.7680.98
466_P501_N1.7620.98
303_S407_G1.7560.98
396_Y399_F1.7520.98
465_A478_V1.7110.98
140_A144_G1.7070.98
217_G221_P1.6710.98
213_G217_G1.6660.98
198_T205_V1.6560.98
221_P227_I1.6460.98
225_N229_N1.6460.98
280_F419_N1.6360.97
208_K213_G1.6220.97
282_V289_Y1.6200.97
498_L507_Q1.5980.97
211_E215_I1.5890.97
196_L205_V1.5790.97
265_S487_K1.5650.97
366_T406_S1.5500.97
342_I370_V1.5270.96
349_E373_M1.5250.96
549_E552_Y1.5080.96
279_S447_Y1.4860.96
276_T280_F1.4840.96
139_N143_G1.4830.95
498_L508_N1.4760.95
366_T369_D1.4750.95
206_N213_G1.4610.95
139_N144_G1.4480.95
196_L202_A1.4430.95
395_P400_L1.4430.95
136_N139_N1.4420.95
223_L227_I1.4340.95
135_V139_N1.4300.94
347_Y365_P1.4280.94
206_N210_I1.4280.94
397_I401_A1.4270.94
390_L393_I1.4110.94
212_L215_I1.4110.94
307_L321_V1.4000.94
170_S187_I1.3980.94
272_I461_V1.3930.94
217_G220_A1.3890.94
231_K234_W1.3840.93
197_F204_S1.3820.93
195_F198_T1.3800.93
196_L204_S1.3790.93
481_L485_V1.3790.93
345_D377_R1.3730.93
272_I282_V1.3670.93
308_S409_S1.3640.93
395_P399_F1.3580.93
195_F202_A1.3550.93
225_N228_S1.3490.93
196_L201_S1.3330.92
524_D528_R1.3280.92
275_F459_F1.3200.92
463_D495_I1.3100.91
172_T183_F1.3020.91
245_N253_N1.2950.91
392_S400_L1.2810.90
253_N545_I1.2800.90
140_A143_G1.2770.90
135_V140_A1.2740.90
460_L490_V1.2710.90
197_F205_V1.2640.90
349_E376_R1.2600.90
525_Y528_R1.2570.90
209_G212_L1.2460.89
207_E212_L1.2400.89
257_L514_I1.2350.89
151_F155_Y1.2310.89
294_A421_I1.2240.88
212_L217_G1.2220.88
271_I275_F1.2190.88
207_E215_I1.2140.88
224_V228_S1.2110.88
258_G262_S1.2090.88
287_G425_S1.2020.87
197_F202_A1.2010.87
286_H488_F1.1930.87
528_R531_S1.1930.87
221_P228_S1.1900.87
512_I519_E1.1850.87
224_V229_N1.1770.86
200_L204_S1.1770.86
138_K145_L1.1710.86
211_E221_P1.1660.86
373_M376_R1.1650.86
256_I495_I1.1620.86
339_I374_I1.1580.85
394_E400_L1.1530.85
138_K144_G1.1520.85
210_I215_I1.1500.85
429_T480_R1.1450.85
104_L183_F1.1440.85
465_A502_I1.1360.84
482_F509_S1.1350.84
339_I370_V1.1330.84
325_L339_I1.1310.84
152_L163_L1.1300.84
375_E398_Q1.1280.84
195_F203_Y1.1280.84
196_L200_L1.1250.84
392_S396_Y1.1230.84
397_I402_N1.1220.84
465_A469_L1.1210.83
221_P224_V1.1150.83
256_I493_I1.1120.83
207_E213_G1.1090.83
445_R488_F1.1060.83
269_K289_Y1.1030.82
448_I485_V1.0950.82
251_N483_A1.0870.82
196_L203_Y1.0870.82
106_T172_T1.0800.81
221_P229_N1.0770.81
195_F200_L1.0750.81
215_I223_L1.0710.81
365_P369_D1.0690.80
305_N347_Y1.0670.80
260_S508_N1.0660.80
513_F555_T1.0610.80
514_I517_V1.0590.80
209_G215_I1.0560.80
199_Q205_V1.0550.80
207_E214_S1.0550.80
211_E214_S1.0530.79
175_F179_N1.0530.79
253_N490_V1.0510.79
483_A496_S1.0510.79
308_S361_N1.0480.79
96_L99_L1.0460.79
290_E296_R1.0350.78
345_D348_A1.0340.78
389_R396_Y1.0330.78
96_L103_A1.0320.78
298_D426_K1.0270.78
219_L223_L1.0240.77
267_L271_I1.0220.77
519_E526_L1.0210.77
422_L443_D1.0180.77
135_V145_L1.0170.77
198_T204_S1.0170.77
213_G221_P1.0160.77
321_V325_L1.0090.76
219_L222_S1.0080.76
215_I218_V1.0030.76
424_F468_I0.9940.75
281_L444_F0.9930.75
499_T517_V0.9910.75
258_G263_G0.9900.75
222_S228_S0.9890.75
91_I94_T0.9880.75
282_V419_N0.9840.75
339_I393_I0.9820.74
223_L228_S0.9820.74
195_F201_S0.9770.74
217_G222_S0.9760.74
231_K236_K0.9750.74
296_R421_I0.9750.74
218_V221_P0.9740.74
177_I181_S0.9740.74
196_L199_Q0.9710.74
197_F203_Y0.9700.73
285_L288_E0.9670.73
347_Y369_D0.9670.73
253_N482_F0.9620.73
233_G236_K0.9610.73
207_E219_L0.9600.73
439_T443_D0.9580.73
459_F493_I0.9530.72
138_K143_G0.9520.72
208_K214_S0.9510.72
217_G223_L0.9510.72
271_I277_D0.9470.72
439_T442_R0.9460.72
179_N205_V0.9440.71
394_E399_F0.9440.71
135_V138_K0.9410.71
206_N215_I0.9410.71
322_A340_F0.9400.71
268_A289_Y0.9400.71
120_F124_I0.9370.71
373_M393_I0.9370.71
210_I221_P0.9350.71
137_K143_G0.9350.71
135_V142_Y0.9330.71
317_R442_R0.9310.70
461_V465_A0.9280.70
349_E372_L0.9270.70
208_K219_L0.9270.70
465_A515_F0.9260.70
220_A228_S0.9260.70
283_F460_L0.9260.70
108_I170_S0.9250.70
368_R372_L0.9230.70
207_E217_G0.9200.69
527_S542_Y0.9200.69
389_R400_L0.9190.69
172_T184_P0.9180.69
140_A145_L0.9180.69
136_N143_G0.9160.69
112_I304_L0.9140.69
217_G225_N0.9120.69
533_S541_I0.9120.69
207_E218_V0.9120.69
363_T408_N0.9110.69
284_D487_K0.9100.69
199_Q202_A0.9090.69
321_V343_I0.9090.69
262_S515_F0.9060.68
206_N209_G0.9040.68
260_S479_E0.9010.68
135_V144_G0.8970.67
210_I214_S0.8960.67
108_I158_L0.8960.67
308_S365_P0.8960.67
96_L172_T0.8950.67
496_S502_I0.8940.67
524_D545_I0.8920.67
305_N309_L0.8920.67
283_F462_I0.8910.67
214_S218_V0.8890.67
213_G223_L0.8850.66
364_P408_N0.8840.66
206_N212_L0.8820.66
210_I218_V0.8770.66
270_S275_F0.8750.66
294_A541_I0.8740.65
212_L220_A0.8700.65
484_E487_K0.8680.65
477_I481_L0.8670.65
220_A226_R0.8650.65
341_N377_R0.8650.65
326_R336_T0.8620.64
317_R321_V0.8600.64
272_I275_F0.8600.64
341_N379_K0.8590.64
482_F494_L0.8590.64
274_K277_D0.8580.64
296_R423_D0.8570.64
137_K145_L0.8570.64
223_L226_R0.8560.64
128_V150_S0.8560.64
541_I561_R0.8540.64
135_V141_I0.8500.63
393_I397_I0.8500.63
197_F200_L0.8480.63
556_V561_R0.8440.63
332_G335_Q0.8430.63
264_K464_E0.8420.63
441_L478_V0.8410.62
294_A487_K0.8400.62
511_Y555_T0.8390.62
424_F427_V0.8390.62
436_L448_I0.8380.62
135_V143_G0.8380.62
224_V227_I0.8350.62
112_I164_F0.8340.62
222_S225_N0.8340.62
438_E442_R0.8320.62
176_F291_I0.8320.62
252_Y491_G0.8310.62
210_I225_N0.8290.61
417_E528_R0.8270.61
226_R229_N0.8260.61
215_I221_P0.8260.61
210_I219_L0.8250.61
253_N269_K0.8250.61
138_K141_I0.8240.61
219_L225_N0.8220.61
281_L422_L0.8190.60
295_E409_S0.8150.60
199_Q204_S0.8150.60
256_I259_T0.8120.60
466_P484_E0.8120.60
487_K506_V0.8110.60
215_I220_A0.8070.59
197_F201_S0.8050.59
443_D446_N0.8040.59
141_I145_L0.8020.59
244_L550_R0.8020.59
335_Q392_S0.8000.59
208_K212_L0.7990.58
427_V436_L0.7990.58
108_I131_L0.7980.58
209_G214_S0.7980.58
486_R497_Q0.7940.58
497_Q508_N0.7930.58
217_G224_V0.7920.58
139_N142_Y0.7920.58
369_D372_L0.7880.57
452_G484_E0.7870.57
467_F480_R0.7870.57
264_K486_R0.7840.57
284_D496_S0.7830.57
258_G495_I0.7830.57
422_L487_K0.7810.57
474_G477_I0.7810.57
218_V229_N0.7800.57
270_S273_G0.7750.56
321_V347_Y0.7730.56
445_R484_E0.7720.56
496_S501_N0.7720.56
271_I274_K0.7670.55
272_I493_I0.7640.55
253_N485_V0.7620.55
315_R321_V0.7620.55
126_L130_R0.7620.55
524_D542_Y0.7610.55
128_V146_I0.7600.55
120_F163_L0.7590.55
374_I390_L0.7580.54
276_T418_S0.7530.54
260_S483_A0.7530.54
327_S438_E0.7520.54
257_L502_I0.7500.54
339_I343_I0.7500.54
211_E223_L0.7480.54
159_S174_L0.7480.54
390_L400_L0.7470.53
265_S278_A0.7470.53
146_I150_S0.7460.53
394_E398_Q0.7450.53
260_S497_Q0.7420.53
222_S227_I0.7410.53
115_I119_S0.7410.53
305_N487_K0.7410.53
307_L343_I0.7400.53
216_E221_P0.7390.53
280_F461_V0.7380.53
264_K497_Q0.7370.52
263_G464_E0.7360.52
218_V223_L0.7350.52
142_Y145_L0.7340.52
507_Q521_K0.7280.52
480_R484_E0.7270.51
220_A223_L0.7270.51
245_N514_I0.7240.51
131_L146_I0.7240.51
217_G228_S0.7230.51
124_I132_N0.7200.51
151_F176_F0.7200.51
232_Y236_K0.7180.51
288_E551_G0.7170.50
219_L229_N0.7170.50
209_G219_L0.7170.50
544_A548_L0.7160.50
132_N146_I0.7150.50
216_E219_L0.7150.50
338_D374_I0.7120.50
212_L218_V0.7090.50
294_A419_N0.7090.50
211_E218_V0.7080.50
104_L172_T0.7060.49
507_Q522_E0.7050.49
501_N509_S0.7050.49
288_E365_P0.7030.49
110_G168_I0.7020.49
218_V225_N0.7020.49
242_F481_L0.7020.49
156_E163_L0.7010.49
445_R449_Y0.7010.49
215_I222_S0.7000.49
484_E501_N0.6980.49
128_V149_I0.6970.48
324_M435_V0.6960.48
427_V554_V0.6960.48
213_G220_A0.6950.48
131_L361_N0.6950.48
479_E501_N0.6950.48
253_N257_L0.6950.48
307_L328_I0.6940.48
180_D463_D0.6940.48
127_N130_R0.6880.48
369_D406_S0.6850.47
434_Y444_F0.6840.47
285_L474_G0.6820.47
194_P201_S0.6800.47
214_S219_L0.6770.46
218_V227_I0.6770.46
391_S400_L0.6760.46
125_L153_I0.6740.46
215_I227_I0.6740.46
542_Y545_I0.6730.46
279_S462_I0.6720.46
214_S228_S0.6710.46
268_A545_I0.6690.46
136_N140_A0.6690.46
218_V228_S0.6690.46
92_L95_F0.6680.46
368_R402_N0.6660.45
448_I488_F0.6650.45
128_V153_I0.6640.45
246_F493_I0.6610.45
188_L332_G0.6600.45
90_L93_S0.6580.45
211_E220_A0.6570.45
296_R307_L0.6550.44
288_E487_K0.6510.44
434_Y443_D0.6510.44
110_G166_G0.6490.44
137_K144_G0.6480.44
128_V132_N0.6480.44
467_F501_N0.6430.43
209_G223_L0.6430.43
396_Y401_A0.6410.43
136_N144_G0.6410.43
222_S226_R0.6400.43
255_V509_S0.6400.43
444_F460_L0.6400.43
448_I484_E0.6380.43
496_S509_S0.6370.43
371_L401_A0.6370.43
305_N365_P0.6360.42
209_G228_S0.6360.42
413_K417_E0.6350.42
137_K140_A0.6350.42
289_Y347_Y0.6340.42
256_I280_F0.6340.42
207_E216_E0.6330.42
182_I186_I0.6320.42
424_F515_F0.6310.42
272_I459_F0.6310.42
309_L347_Y0.6310.42
217_G227_I0.6290.42
288_E427_V0.6290.42
176_F413_K0.6280.42
206_N219_L0.6270.42
286_H445_R0.6250.41
219_L227_I0.6240.41
141_I144_G0.6230.41
392_S397_I0.6210.41
258_G261_G0.6200.41
173_L176_F0.6190.41
478_V483_A0.6190.41
131_L149_I0.6180.41
285_L498_L0.6170.41
340_F496_S0.6150.40
214_S220_A0.6140.40
213_G218_V0.6130.40
376_R526_L0.6130.40
258_G464_E0.6120.40
194_P200_L0.6110.40
205_V211_E0.6100.40
137_K141_I0.6070.40
390_L394_E0.6060.40
442_R445_R0.6060.40
212_L222_S0.6030.39
317_R347_Y0.6030.39
405_L432_L0.6010.39
181_S185_L0.6000.39
256_I380_L0.6000.39
215_I225_N0.6000.39
389_R399_F0.6000.39
247_D278_A0.5970.39
479_E503_E0.5960.39
106_T110_G0.5960.39
136_N145_L0.5950.39
208_K220_A0.5950.39
210_I216_E0.5950.39
265_S415_I0.5940.38
433_K448_I0.5940.38
316_Q440_I0.5920.38
159_S172_T0.5920.38
207_E229_N0.5910.38
466_P496_S0.5900.38
266_S282_V0.5890.38
261_G497_Q0.5870.38
97_N101_Y0.5870.38
213_G229_N0.5860.38
433_K469_L0.5860.38
367_F394_E0.5860.38
481_L492_M0.5850.38
522_E530_L0.5850.38
471_K474_G0.5840.38
343_I346_T0.5830.37
440_I444_F0.5830.37
123_E204_S0.5810.37
253_N328_I0.5810.37
247_D252_Y0.5790.37
208_K217_G0.5790.37
212_L216_E0.5790.37
207_E220_A0.5790.37
107_I111_V0.5790.37
299_I303_S0.5780.37
122_D126_L0.5770.37
521_K526_L0.5760.37
231_K267_L0.5750.37
320_E324_M0.5730.37
106_T173_L0.5730.37
216_E222_S0.5720.36
124_I130_R0.5710.36
469_L511_Y0.5700.36
423_D426_K0.5690.36
281_L458_K0.5680.36
259_T502_I0.5680.36
335_Q374_I0.5670.36
334_L392_S0.5650.36
487_K490_V0.5650.36
339_I458_K0.5640.36
305_N321_V0.5630.36
475_L504_N0.5610.35
252_Y485_V0.5600.35
431_E468_I0.5600.35
466_P517_V0.5590.35
208_K216_E0.5590.35
265_S449_Y0.5590.35
215_I224_V0.5580.35
136_N141_I0.5580.35
116_S128_V0.5570.35
218_V222_S0.5570.35
208_K224_V0.5560.35
220_A229_N0.5560.35
261_G501_N0.5540.35
318_A344_M0.5540.35
96_L124_I0.5540.35
308_S408_N0.5530.35
180_D184_P0.5530.35
179_N343_I0.5520.35
324_M477_I0.5510.35
481_L488_F0.5500.34
294_A545_I0.5490.34
215_I228_S0.5490.34
219_L559_D0.5480.34
140_A372_L0.5480.34
131_L187_I0.5480.34
177_I184_P0.5480.34
213_G216_E0.5470.34
464_E486_R0.5470.34
498_L501_N0.5470.34
105_A148_L0.5460.34
436_L439_T0.5450.34
194_P204_S0.5450.34
370_V374_I0.5450.34
258_G264_K0.5440.34
409_S412_M0.5440.34
100_G238_S0.5440.34
399_F402_N0.5440.34
282_V421_I0.5420.34
267_L515_F0.5420.34
115_I165_V0.5420.34
194_P205_V0.5420.34
372_L375_E0.5410.34
245_N423_D0.5410.34
511_Y526_L0.5390.33
181_S293_K0.5390.33
93_S96_L0.5380.33
122_D239_N0.5370.33
92_L148_L0.5360.33
295_E420_I0.5350.33
244_L555_T0.5350.33
469_L505_I0.5340.33
269_K365_P0.5340.33
270_S277_D0.5340.33
542_Y546_R0.5340.33
509_S512_I0.5340.33
127_N162_F0.5330.33
212_L223_L0.5330.33
210_I220_A0.5310.33
379_K391_S0.5310.33
247_D491_G0.5310.33
130_R134_S0.5310.33
228_S528_R0.5310.33
124_I345_D0.5300.33
187_I416_F0.5300.33
131_L134_S0.5300.33
260_S466_P0.5300.33
217_G229_N0.5290.33
195_F199_Q0.5290.33
214_S217_G0.5270.32
285_L406_S0.5260.32
170_S190_W0.5260.32
221_P226_R0.5250.32
362_L408_N0.5240.32
157_V339_I0.5230.32
209_G217_G0.5220.32
216_E220_A0.5220.32
211_E225_N0.5210.32
307_L369_D0.5200.32
287_G424_F0.5200.32
466_P499_T0.5200.32
391_S397_I0.5200.32
476_E530_L0.5200.32
110_G167_S0.5190.32
111_V120_F0.5190.32
121_P161_P0.5180.32
289_Y487_K0.5180.32
304_L459_F0.5170.32
194_P202_A0.5170.32
254_I511_Y0.5170.32
433_K484_E0.5150.31
330_K472_E0.5150.31
210_I223_L0.5140.31
422_L428_T0.5120.31
218_V226_R0.5110.31
393_I396_Y0.5100.31
194_P199_Q0.5100.31
213_G226_R0.5060.31
513_F553_V0.5060.31
441_L462_I0.5060.31
112_I293_K0.5060.31
251_N526_L0.5050.31
246_F254_I0.5050.31
260_S477_I0.5050.31
514_I545_I0.5040.30
231_K239_N0.5030.30
142_Y233_G0.5030.30
480_R498_L0.5020.30
136_N142_Y0.5020.30
464_E497_Q0.5010.30
213_G227_I0.5010.30
415_I422_L0.5000.30
318_A462_I0.5000.30
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ag6A 2 0.5857 100 0.547 Contact Map
4d2iA 3 0.7552 100 0.61 Contact Map
1e9rA 3 0.6066 100 0.716 Contact Map
2iusA 1 0.5962 99.5 0.852 Contact Map
2iutA 2 0.5402 99.2 0.879 Contact Map
4lyaA 1 0.4213 99.2 0.88 Contact Map
4nh0A 1 0.4301 98.5 0.906 Contact Map
4kfuA 1 0.3566 98.2 0.913 Contact Map
2r2aA 1 0.3199 97.7 0.923 Contact Map
1pznA 5 0.4668 97.4 0.927 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0133 seconds.