CBIA - SULSO - GREMLIN Contacts

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CBIA - Cobyrinate a,c-diamide synthase

UniProt:	Q980B1	Sequences: MKRILLSSDRSGSGKTLITSAIMRALSKKYKVRGFKAGPDFIDPGYHKIATGFPSINLDLWMMGKNNVKRSLAKYGKEFDIGIIEGVMGLYDGVDTLYSTYELAKVTKTPIILIINCSNIGSTVGAIVKGLKYYRSDVSIRGVIFNKIASETHYNYCRNAVEDVEVLGYVPFDKNLEIKSRHLGLVTVEDNREVQNLIRYASELVEKYVDLDKIYEMASDEDLEIDLPEDNESNGVKRKMAIAYDPAFSFYYQENLDILKNKYELEFFSPLNNEYVEDAEAIYIGGGYPELHLNELEKSTRTKKWLKNMSYAGVKIYAECGGLMYLSKNLIDENNKNHSMTGIFDIDIKTKDKLTIGYTELEAVKENFIVNKNNVVRGHEFHVSKPISVNEKEFVFKVRIGKGIINKLDGVKSNNTVASYSHLHFSNFQLRIVF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	434 (426)
Sequences:	2252 (1676)
Seq/√Len:	81.2

HALSA - CBIA
SULSO - CBIA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
5_L	100_T	4.557	1.00
129_K	133_Y	4.138	1.00
310_S	316_I	4.070	1.00
241_A	279_A	4.059	1.00
123_T	131_L	3.980	1.00
28_K	203_E	3.928	1.00
239_K	264_E	3.866	1.00
309_M	314_V	3.597	1.00
384_S	420_Y	3.172	1.00
84_I	109_T	3.170	1.00
116_N	147_K	2.975	1.00
171_P	208_Y	2.967	1.00
251_Y	285_G	2.921	1.00
29_K	206_E	2.871	1.00
282_I	306_L	2.866	1.00
329_N	347_D	2.756	1.00
72_L	107_T	2.699	1.00
246_P	272_N	2.671	1.00
154_Y	158_R	2.664	1.00
34_G	51_T	2.517	1.00
105_K	135_R	2.498	1.00
8_S	13_S	2.484	1.00
310_S	416_T	2.470	1.00
19_T	23_M	2.426	1.00
256_L	265_L	2.399	1.00
328_K	345_D	2.386	1.00
302_T	305_W	2.385	1.00
3_R	109_T	2.379	1.00
29_K	212_D	2.359	1.00
329_N	337_N	2.335	1.00
28_K	199_R	2.272	1.00
105_K	137_D	2.270	1.00
303_K	307_K	2.263	1.00
28_K	206_E	2.238	1.00
23_M	51_T	2.199	1.00
205_V	209_V	2.179	1.00
371_N	374_N	2.143	1.00
76_G	82_G	2.056	1.00
294_N	298_K	2.054	1.00
154_Y	169_Y	2.040	1.00
21_A	205_V	2.037	1.00
242_I	267_F	2.032	1.00
276_V	305_W	2.029	1.00
115_I	128_V	2.029	1.00
328_K	347_D	2.020	1.00
145_F	161_V	1.976	1.00
310_S	343_I	1.920	1.00
167_L	217_M	1.909	1.00
300_T	303_K	1.908	1.00
275_Y	305_W	1.886	1.00
360_E	375_V	1.886	1.00
112_I	214_I	1.886	1.00
23_M	34_G	1.877	1.00
306_L	341_T	1.845	1.00
240_M	263_Y	1.838	1.00
366_E	371_N	1.829	1.00
37_A	103_L	1.813	1.00
24_R	199_R	1.813	1.00
128_V	164_V	1.780	1.00
64_G	67_N	1.774	1.00
239_K	266_E	1.774	1.00
47_H	55_S	1.771	1.00
18_I	170_V	1.767	1.00
244_Y	267_F	1.758	1.00
165_E	213_K	1.728	1.00
360_E	377_R	1.718	1.00
6_L	114_I	1.709	1.00
28_K	202_S	1.701	1.00
331_I	337_N	1.695	1.00
128_V	161_V	1.694	1.00
243_A	268_F	1.685	1.00
61_W	377_R	1.660	1.00
33_R	53_F	1.660	1.00
23_M	47_H	1.654	1.00
145_F	166_V	1.641	1.00
304_K	308_N	1.627	1.00
74_K	261_N	1.626	1.00
307_K	311_Y	1.621	1.00
366_E	372_K	1.614	1.00
26_L	81_I	1.609	1.00
260_K	267_F	1.604	1.00
151_E	171_P	1.603	1.00
253_Q	260_K	1.601	1.00
24_R	28_K	1.599	1.00
25_A	211_L	1.591	1.00
327_S	346_I	1.581	1.00
125_G	160_A	1.580	1.00
361_L	421_S	1.578	1.00
292_H	295_E	1.578	1.00
282_I	314_V	1.567	1.00
242_I	265_L	1.564	1.00
276_V	279_A	1.563	1.00
9_D	13_S	1.561	1.00
324_M	348_I	1.557	1.00
327_S	348_I	1.551	1.00
297_E	339_S	1.548	1.00
344_F	416_T	1.542	0.99
24_R	195_Q	1.535	0.99
253_Q	257_D	1.532	0.99
5_L	109_T	1.531	0.99
303_K	341_T	1.530	0.99
311_Y	414_N	1.528	0.99
120_I	127_I	1.518	0.99
18_I	144_I	1.510	0.99
297_E	303_K	1.507	0.99
363_A	370_V	1.501	0.99
362_E	375_V	1.490	0.99
151_E	155_N	1.482	0.99
209_V	214_I	1.480	0.99
213_K	216_E	1.476	0.99
187_T	249_S	1.473	0.99
108_K	139_S	1.457	0.99
257_D	260_K	1.455	0.99
301_R	305_W	1.450	0.99
65_K	102_E	1.440	0.99
30_Y	80_D	1.438	0.99
293_L	338_H	1.425	0.99
112_I	144_I	1.424	0.99
81_I	215_Y	1.410	0.99
362_E	397_K	1.410	0.99
273_N	302_T	1.399	0.99
299_S	302_T	1.395	0.99
350_T	420_Y	1.391	0.99
112_I	167_L	1.389	0.99
23_M	83_I	1.377	0.99
37_A	87_V	1.370	0.99
221_E	224_E	1.369	0.99
350_T	384_S	1.349	0.99
242_I	256_L	1.347	0.99
4_I	83_I	1.345	0.99
316_I	416_T	1.341	0.99
118_S	147_K	1.336	0.99
351_K	385_K	1.336	0.99
24_R	202_S	1.327	0.98
4_I	218_A	1.320	0.98
240_M	281_A	1.318	0.98
56_I	257_D	1.315	0.98
3_R	224_E	1.313	0.98
337_N	347_D	1.305	0.98
23_M	55_S	1.303	0.98
299_S	325_Y	1.299	0.98
111_I	138_V	1.263	0.98
117_C	157_C	1.262	0.98
305_W	309_M	1.262	0.98
30_Y	215_Y	1.248	0.98
324_M	384_S	1.245	0.98
243_A	270_P	1.239	0.98
241_A	282_I	1.234	0.98
115_I	124_V	1.229	0.97
170_V	204_L	1.225	0.97
31_K	80_D	1.224	0.97
276_V	302_T	1.222	0.97
203_E	207_K	1.216	0.97
284_I	306_L	1.214	0.97
60_L	106_V	1.212	0.97
7_S	111_I	1.209	0.97
87_V	100_T	1.208	0.97
132_K	140_I	1.203	0.97
293_L	330_L	1.199	0.97
72_L	109_T	1.196	0.97
60_L	103_L	1.190	0.97
187_T	288_Y	1.190	0.97
169_Y	208_Y	1.179	0.97
3_R	221_E	1.177	0.97
18_I	114_I	1.173	0.97
129_K	134_Y	1.173	0.97
135_R	138_V	1.171	0.97
260_K	264_E	1.167	0.97
174_K	177_E	1.157	0.96
81_I	218_A	1.145	0.96
255_N	425_F	1.144	0.96
4_I	112_I	1.144	0.96
97_L	102_E	1.133	0.96
245_D	269_S	1.127	0.96
326_L	416_T	1.124	0.96
3_R	72_L	1.113	0.95
48_K	56_I	1.109	0.95
239_K	279_A	1.105	0.95
238_R	263_Y	1.104	0.95
176_L	204_L	1.103	0.95
361_L	398_V	1.103	0.95
31_K	78_E	1.101	0.95
318_A	418_A	1.099	0.95
296_L	325_Y	1.096	0.95
90_L	138_V	1.095	0.95
70_R	74_K	1.087	0.95
324_M	330_L	1.085	0.95
273_N	299_S	1.080	0.95
26_L	215_Y	1.076	0.95
302_T	325_Y	1.075	0.94
331_I	349_K	1.074	0.94
3_R	108_K	1.069	0.94
396_F	417_V	1.067	0.94
266_E	279_A	1.064	0.94
288_Y	291_L	1.064	0.94
117_C	148_I	1.062	0.94
68_V	103_L	1.062	0.94
349_K	385_K	1.061	0.94
175_N	200_Y	1.055	0.94
149_A	172_F	1.045	0.94
331_I	347_D	1.043	0.94
67_N	71_S	1.040	0.93
302_T	306_L	1.039	0.93
167_L	214_I	1.033	0.93
364_V	397_K	1.027	0.93
69_K	106_V	1.021	0.93
34_G	55_S	1.021	0.93
31_K	53_F	1.020	0.93
173_D	204_L	1.017	0.93
2_K	221_E	1.011	0.92
56_I	75_Y	1.008	0.92
274_E	299_S	1.005	0.92
120_I	124_V	0.997	0.92
53_F	79_F	0.995	0.92
65_K	106_V	0.986	0.92
316_I	343_I	0.986	0.92
202_S	206_E	0.984	0.91
6_L	112_I	0.980	0.91
105_K	138_V	0.980	0.91
113_L	123_T	0.972	0.91
346_I	386_P	0.968	0.91
155_N	159_N	0.963	0.91
239_K	278_D	0.963	0.91
400_I	404_I	0.958	0.90
282_I	316_I	0.958	0.90
33_R	79_F	0.953	0.90
327_S	386_P	0.952	0.90
122_S	134_Y	0.945	0.90
101_Y	138_V	0.944	0.90
26_L	30_Y	0.944	0.90
98_Y	103_L	0.944	0.90
9_D	131_L	0.940	0.89
283_Y	317_Y	0.935	0.89
46_Y	194_V	0.934	0.89
282_I	309_M	0.931	0.89
328_K	346_I	0.930	0.89
199_R	202_S	0.925	0.89
60_L	68_V	0.924	0.89
117_C	145_F	0.923	0.89
8_S	131_L	0.921	0.88
204_L	208_Y	0.917	0.88
324_M	340_M	0.910	0.88
29_K	215_Y	0.909	0.88
309_M	316_I	0.907	0.88
10_R	13_S	0.904	0.88
254_E	257_D	0.904	0.88
45_G	187_T	0.904	0.88
309_M	312_A	0.903	0.87
303_K	325_Y	0.899	0.87
347_D	387_I	0.899	0.87
148_I	157_C	0.898	0.87
274_E	301_R	0.898	0.87
370_V	374_N	0.897	0.87
210_D	213_K	0.897	0.87
152_T	155_N	0.896	0.87
96_T	105_K	0.887	0.87
53_F	78_E	0.883	0.86
49_I	194_V	0.882	0.86
25_A	29_K	0.880	0.86
158_R	162_E	0.879	0.86
147_K	172_F	0.878	0.86
297_E	338_H	0.872	0.86
180_S	383_V	0.871	0.86
173_D	176_L	0.871	0.86
239_K	280_E	0.869	0.85
367_N	370_V	0.867	0.85
327_S	344_F	0.867	0.85
173_D	200_Y	0.866	0.85
281_A	315_K	0.863	0.85
35_F	82_G	0.862	0.85
10_R	116_N	0.862	0.85
359_T	400_I	0.860	0.85
273_N	325_Y	0.858	0.85
90_L	111_I	0.857	0.85
317_Y	417_V	0.854	0.84
68_V	106_V	0.853	0.84
33_R	48_K	0.850	0.84
63_M	71_S	0.849	0.84
258_I	262_K	0.847	0.84
22_I	205_V	0.846	0.84
349_K	387_I	0.843	0.84
145_F	169_Y	0.842	0.84
237_K	264_E	0.842	0.84
303_K	340_M	0.841	0.83
91_Y	138_V	0.841	0.83
127_I	131_L	0.841	0.83
3_R	84_I	0.839	0.83
17_L	47_H	0.837	0.83
304_K	307_K	0.833	0.83
88_M	121_G	0.831	0.83
255_N	259_L	0.821	0.82
48_K	54_P	0.813	0.81
113_L	131_L	0.813	0.81
193_E	196_N	0.812	0.81
198_I	201_A	0.806	0.81
300_T	304_K	0.805	0.81
75_Y	254_E	0.805	0.81
167_L	213_K	0.804	0.81
100_T	109_T	0.804	0.81
24_R	50_A	0.803	0.81
141_R	217_M	0.802	0.80
328_K	342_G	0.800	0.80
104_A	111_I	0.788	0.79
129_K	132_K	0.783	0.79
2_K	218_A	0.782	0.79
276_V	299_S	0.781	0.79
47_H	51_T	0.776	0.78
84_I	107_T	0.775	0.78
203_E	206_E	0.774	0.78
161_V	166_V	0.770	0.78
25_A	206_E	0.770	0.78
303_K	339_S	0.767	0.77
61_W	268_F	0.767	0.77
363_A	367_N	0.766	0.77
60_L	102_E	0.765	0.77
212_D	215_Y	0.765	0.77
96_T	122_S	0.754	0.76
45_G	188_V	0.753	0.76
88_M	92_D	0.747	0.76
274_E	302_T	0.746	0.75
125_G	134_Y	0.745	0.75
2_K	219_S	0.745	0.75
235_G	238_R	0.740	0.75
42_I	46_Y	0.740	0.75
66_N	294_N	0.740	0.75
42_I	182_H	0.739	0.75
26_L	83_I	0.738	0.75
102_E	106_V	0.738	0.75
308_N	311_Y	0.738	0.75
355_T	385_K	0.736	0.74
115_I	131_L	0.734	0.74
294_N	336_K	0.733	0.74
37_A	100_T	0.732	0.74
246_P	295_E	0.730	0.74
409_D	421_S	0.730	0.74
238_R	241_A	0.727	0.74
9_D	123_T	0.726	0.73
90_L	135_R	0.725	0.73
204_L	207_K	0.723	0.73
310_S	341_T	0.720	0.73
7_S	87_V	0.718	0.73
356_I	359_T	0.717	0.73
41_F	249_S	0.716	0.72
63_M	68_V	0.712	0.72
24_R	27_S	0.712	0.72
56_I	424_H	0.712	0.72
343_I	416_T	0.712	0.72
255_N	283_Y	0.711	0.72
72_L	82_G	0.709	0.72
362_E	399_R	0.709	0.72
154_Y	171_P	0.709	0.72
86_G	100_T	0.708	0.72
16_T	185_L	0.708	0.72
117_C	166_V	0.708	0.72
276_V	309_M	0.708	0.72
88_M	180_S	0.707	0.71
191_N	197_L	0.706	0.71
308_N	312_A	0.706	0.71
213_K	217_M	0.705	0.71
327_S	330_L	0.705	0.71
187_T	291_L	0.704	0.71
27_S	50_A	0.704	0.71
293_L	297_E	0.704	0.71
306_L	325_Y	0.704	0.71
187_T	190_D	0.704	0.71
243_A	269_S	0.702	0.71
279_A	314_V	0.701	0.71
145_F	157_C	0.696	0.70
121_G	156_Y	0.695	0.70
22_I	26_L	0.695	0.70
295_E	307_K	0.695	0.70
275_Y	302_T	0.693	0.70
320_C	422_H	0.692	0.70
239_K	267_F	0.692	0.70
6_L	125_G	0.692	0.70
92_D	357_G	0.691	0.70
3_R	222_D	0.691	0.70
398_V	421_S	0.690	0.70
189_E	244_Y	0.689	0.70
30_Y	81_I	0.688	0.69
364_V	408_L	0.688	0.69
217_M	220_D	0.687	0.69
411_V	418_A	0.682	0.69
401_G	404_I	0.681	0.69
193_E	197_L	0.679	0.68
61_W	360_E	0.678	0.68
25_A	205_V	0.678	0.68
323_L	418_A	0.677	0.68
61_W	98_Y	0.676	0.68
90_L	101_Y	0.676	0.68
356_I	407_K	0.676	0.68
62_M	424_H	0.675	0.68
62_M	255_N	0.675	0.68
183_L	379_H	0.674	0.68
150_S	172_F	0.674	0.68
10_R	120_I	0.672	0.68
323_L	386_P	0.670	0.67
23_M	32_V	0.667	0.67
157_C	161_V	0.667	0.67
178_I	191_N	0.666	0.67
249_S	288_Y	0.663	0.67
200_Y	203_E	0.662	0.66
5_L	84_I	0.661	0.66
273_N	301_R	0.661	0.66
22_I	214_I	0.660	0.66
313_G	415_N	0.660	0.66
179_K	202_S	0.659	0.66
142_G	167_L	0.656	0.66
268_F	302_T	0.655	0.66
363_A	373_N	0.653	0.65
363_A	374_N	0.653	0.65
124_V	145_F	0.649	0.65
26_L	211_L	0.649	0.65
64_G	68_V	0.649	0.65
45_G	249_S	0.648	0.65
294_N	338_H	0.648	0.65
56_I	254_E	0.648	0.65
218_A	221_E	0.647	0.65
143_V	161_V	0.646	0.65
46_Y	191_N	0.645	0.64
331_I	335_N	0.639	0.64
284_I	321_G	0.638	0.64
149_A	355_T	0.637	0.63
151_E	207_K	0.637	0.63
323_L	419_S	0.636	0.63
195_Q	199_R	0.633	0.63
317_Y	423_L	0.631	0.63
241_A	266_E	0.630	0.63
329_N	339_S	0.630	0.63
291_L	383_V	0.628	0.62
108_K	222_D	0.628	0.62
256_L	267_F	0.628	0.62
65_K	69_K	0.627	0.62
251_Y	265_L	0.627	0.62
360_E	399_R	0.625	0.62
4_I	214_I	0.625	0.62
365_K	393_E	0.623	0.62
35_F	75_Y	0.622	0.62
123_T	127_I	0.621	0.62
101_Y	135_R	0.620	0.61
158_R	210_D	0.620	0.61
214_I	218_A	0.619	0.61
115_I	123_T	0.618	0.61
6_L	18_I	0.617	0.61
330_L	340_M	0.616	0.61
182_H	320_C	0.615	0.61
22_I	211_L	0.613	0.61
225_I	230_D	0.612	0.60
359_T	380_E	0.611	0.60
311_Y	413_S	0.611	0.60
109_T	221_E	0.610	0.60
41_F	324_M	0.608	0.60
331_I	387_I	0.608	0.60
102_E	135_R	0.607	0.60
18_I	205_V	0.607	0.60
140_I	164_V	0.606	0.60
88_M	183_L	0.605	0.60
158_R	166_V	0.605	0.60
162_E	209_V	0.603	0.59
170_V	201_A	0.602	0.59
373_N	378_G	0.602	0.59
71_S	103_L	0.599	0.59
48_K	76_G	0.598	0.59
333_E	336_K	0.598	0.59
48_K	51_T	0.598	0.59
49_I	195_Q	0.597	0.59
363_A	396_F	0.597	0.59
34_G	420_Y	0.597	0.59
183_L	320_C	0.595	0.58
178_I	186_V	0.595	0.58
105_K	139_S	0.594	0.58
124_V	157_C	0.594	0.58
390_N	413_S	0.592	0.58
307_K	316_I	0.592	0.58
324_M	327_S	0.592	0.58
5_L	103_L	0.591	0.58
378_G	421_S	0.590	0.58
60_L	64_G	0.590	0.58
184_G	250_F	0.587	0.57
272_N	302_T	0.586	0.57
141_R	165_E	0.586	0.57
412_K	415_N	0.586	0.57
232_E	304_K	0.584	0.57
62_M	378_G	0.583	0.57
88_M	156_Y	0.583	0.57
181_R	250_F	0.581	0.56
91_Y	152_T	0.581	0.56
269_S	302_T	0.580	0.56
149_A	356_I	0.579	0.56
153_H	356_I	0.578	0.56
310_S	344_F	0.578	0.56
118_S	172_F	0.578	0.56
76_G	79_F	0.578	0.56
214_I	219_S	0.574	0.56
21_A	25_A	0.574	0.56
396_F	400_I	0.573	0.55
279_A	282_I	0.573	0.55
54_P	253_Q	0.571	0.55
363_A	412_K	0.571	0.55
188_V	194_V	0.571	0.55
27_S	51_T	0.571	0.55
400_I	403_G	0.570	0.55
363_A	366_E	0.569	0.55
369_I	373_N	0.569	0.55
91_Y	197_L	0.569	0.55
266_E	281_A	0.568	0.55
264_E	336_K	0.568	0.55
66_N	69_K	0.568	0.55
165_E	168_G	0.568	0.55
271_L	357_G	0.568	0.55
27_S	53_F	0.567	0.55
33_R	56_I	0.566	0.55
334_N	352_D	0.566	0.55
4_I	81_I	0.565	0.54
25_A	202_S	0.565	0.54
88_M	357_G	0.563	0.54
11_S	88_M	0.563	0.54
234_N	295_E	0.563	0.54
171_P	204_L	0.563	0.54
57_N	358_Y	0.562	0.54
400_I	407_K	0.562	0.54
81_I	212_D	0.560	0.54
214_I	217_M	0.560	0.54
217_M	221_E	0.560	0.54
22_I	83_I	0.559	0.54
172_F	356_I	0.559	0.54
87_V	354_L	0.558	0.54
20_S	50_A	0.558	0.54
51_T	55_S	0.557	0.53
250_F	381_F	0.557	0.53
141_R	167_L	0.557	0.53
303_K	343_I	0.554	0.53
250_F	320_C	0.554	0.53
63_M	67_N	0.553	0.53
181_R	289_P	0.553	0.53
7_S	90_L	0.553	0.53
39_P	92_D	0.553	0.53
17_L	350_T	0.550	0.52
140_I	144_I	0.550	0.52
395_V	400_I	0.550	0.52
166_V	169_Y	0.549	0.52
180_S	324_M	0.549	0.52
88_M	354_L	0.548	0.52
361_L	396_F	0.548	0.52
104_A	138_V	0.548	0.52
153_H	378_G	0.548	0.52
275_Y	301_R	0.545	0.52
250_F	379_H	0.545	0.52
257_D	261_N	0.544	0.52
108_K	224_E	0.544	0.52
67_N	424_H	0.544	0.52
60_L	98_Y	0.544	0.52
273_N	305_W	0.543	0.52
398_V	401_G	0.542	0.51
284_I	314_V	0.541	0.51
103_L	106_V	0.540	0.51
241_A	284_I	0.540	0.51
234_N	237_K	0.539	0.51
244_Y	256_L	0.538	0.51
251_Y	283_Y	0.538	0.51
317_Y	410_G	0.538	0.51
306_L	343_I	0.538	0.51
344_F	411_V	0.538	0.51
91_Y	98_Y	0.538	0.51
154_Y	166_V	0.537	0.51
359_T	421_S	0.537	0.51
20_S	55_S	0.536	0.51
90_L	104_A	0.536	0.51
183_L	381_F	0.536	0.51
13_S	17_L	0.536	0.51
187_T	191_N	0.535	0.51
396_F	409_D	0.535	0.51
271_L	295_E	0.534	0.50
196_N	199_R	0.534	0.50
397_K	406_N	0.533	0.50
122_S	285_G	0.533	0.50
41_F	217_M	0.533	0.50
397_K	408_L	0.532	0.50
62_M	427_N	0.532	0.50
348_I	386_P	0.532	0.50
11_S	87_V	0.532	0.50
259_L	318_A	0.531	0.50
21_A	170_V	0.531	0.50
75_Y	257_D	0.530	0.50
19_T	47_H	0.530	0.50
120_I	131_L	0.530	0.50
321_G	324_M	0.527	0.49
96_T	135_R	0.525	0.49
108_K	137_D	0.524	0.49
248_F	273_N	0.523	0.49
144_I	166_V	0.523	0.49
3_R	218_A	0.522	0.49
20_S	46_Y	0.521	0.49
196_N	200_Y	0.521	0.49
241_A	268_F	0.521	0.49
320_C	379_H	0.521	0.49
148_I	154_Y	0.520	0.49
32_V	80_D	0.520	0.49
44_P	188_V	0.520	0.49
149_A	153_H	0.519	0.48
283_Y	344_F	0.519	0.48
63_M	424_H	0.518	0.48
11_S	15_K	0.517	0.48
323_L	409_D	0.517	0.48
182_H	381_F	0.516	0.48
394_F	404_I	0.516	0.48
186_V	190_D	0.515	0.48
387_I	391_E	0.515	0.48
323_L	383_V	0.514	0.48
213_K	219_S	0.513	0.48
283_Y	425_F	0.513	0.48
88_M	425_F	0.512	0.48
102_E	105_K	0.512	0.48
187_T	194_V	0.512	0.48
203_E	242_I	0.512	0.48
238_R	264_E	0.511	0.47
324_M	331_I	0.511	0.47
58_L	68_V	0.511	0.47
71_S	426_S	0.511	0.47
352_D	385_K	0.511	0.47
317_Y	425_F	0.510	0.47
366_E	369_I	0.510	0.47
19_T	34_G	0.510	0.47
98_Y	123_T	0.510	0.47
162_E	166_V	0.510	0.47
394_F	409_D	0.509	0.47
67_N	426_S	0.508	0.47
398_V	409_D	0.507	0.47
281_A	314_V	0.507	0.47
27_S	81_I	0.507	0.47
324_M	420_Y	0.506	0.47
250_F	290_E	0.504	0.46
307_K	341_T	0.503	0.46
45_G	189_E	0.503	0.46
145_F	154_Y	0.502	0.46
320_C	381_F	0.502	0.46
258_I	429_Q	0.501	0.46
66_N	216_E	0.500	0.46
288_Y	333_E	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1s1mA	4	0.9286	100	0.681	Contact Map
1vcoA	4	0.9309	100	0.693	Contact Map
3nvaA	2	0.9332	100	0.709	Contact Map
4zdjA	4	0.9101	100	0.714	Contact Map
4a0gA	2	0.8687	100	0.822	Contact Map
3fgnA	2	0.4562	99.9	0.86	Contact Map
3fijA	4	0.4263	99.9	0.864	Contact Map
2issD	1	0.4101	99.9	0.866	Contact Map
1ka9H	1	0.4217	99.9	0.868	Contact Map
3ug7A	4	0.4309	99.9	0.869	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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