GREMLIN Database
RS15 - 30S ribosomal protein S15
UniProt: Q980A8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 152 (146)
Sequences: 391 (210)
Seq/√Len: 17.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
96_V116_I7.2231.00
65_V72_I4.9271.00
67_K75_E4.0341.00
133_L137_W3.2600.99
97_R141_P2.5600.96
96_V109_A2.5070.96
35_V72_I2.4220.95
14_R60_L2.3840.95
24_V64_I2.1660.91
117_E139_Y2.1630.91
143_K147_L2.1300.90
145_E148_V2.1000.90
32_E36_E1.9390.86
61_V72_I1.8580.83
55_Q61_V1.8380.82
104_P119_K1.8120.81
24_V59_P1.7630.79
32_E131_G1.7600.79
116_I119_K1.7590.79
26_L58_I1.7360.78
82_I132_K1.7160.78
41_R118_S1.6340.74
34_L37_E1.6200.73
29_E32_E1.6140.73
34_L131_G1.6030.72
40_K78_L1.5880.72
19_G31_V1.5410.69
36_E76_R1.5340.69
46_S68_K1.5210.68
92_K104_P1.4920.67
95_N112_G1.4810.66
24_V30_E1.4650.65
24_V27_T1.4300.63
15_P39_A1.4240.63
40_K137_W1.4080.62
76_R132_K1.4060.62
144_A147_L1.3700.60
93_A139_Y1.3420.58
98_R103_Y1.3050.56
46_S84_E1.3020.56
59_P111_K1.2960.56
113_L117_E1.2890.55
69_V96_V1.2860.55
53_R84_E1.2390.52
34_L38_L1.2320.52
101_N110_K1.2290.52
134_P137_W1.2190.51
110_K114_E1.2000.50
58_I62_K1.1970.50
15_P121_R1.1870.49
98_R101_N1.1810.49
33_M37_E1.1730.48
137_W146_L1.1670.48
108_T112_G1.1340.46
82_I148_V1.1030.44
10_S81_Q1.1020.44
120_I139_Y1.1010.44
140_D143_K1.0880.43
74_E131_G1.0740.42
124_T137_W1.0560.41
10_S32_E1.0560.41
87_F91_R1.0500.41
93_A117_E1.0410.40
46_S63_Q1.0400.40
30_E128_K1.0380.40
24_V63_Q1.0380.40
5_R14_R1.0370.40
39_A80_P1.0360.40
61_V105_R1.0330.40
91_R107_K1.0150.39
35_V65_V1.0020.38
14_R69_V0.9860.37
27_T140_D0.9830.37
143_K148_V0.9780.37
94_V144_A0.9770.37
98_R146_L0.9680.36
97_R114_E0.9620.36
117_E120_I0.9600.36
71_Q74_E0.9600.36
45_P70_T0.9580.36
103_Y141_P0.9550.35
19_G58_I0.9510.35
81_Q148_V0.9320.34
36_E130_I0.9200.34
25_R121_R0.9140.33
38_L61_V0.9140.33
68_K90_I0.9090.33
55_Q59_P0.9050.33
7_K118_S0.8940.32
138_V146_L0.8910.32
59_P119_K0.8840.32
55_Q131_G0.8820.31
72_I86_L0.8730.31
6_A119_K0.8720.31
10_S136_E0.8640.31
34_L60_L0.8580.30
15_P118_S0.8550.30
94_V148_V0.8550.30
104_P116_I0.8530.30
58_I90_I0.8500.30
57_G125_R0.8380.29
85_D127_Y0.8280.29
16_A74_E0.8140.28
27_T36_E0.8140.28
68_K87_F0.8090.28
70_T79_A0.8060.28
41_R110_K0.7980.27
43_Y131_G0.7950.27
60_L63_Q0.7800.26
20_A130_I0.7800.26
41_R109_A0.7730.26
9_K72_I0.7670.26
108_T111_K0.7640.26
74_E79_A0.7640.26
4_R7_K0.7630.26
36_E81_Q0.7620.26
53_R59_P0.7590.25
4_R102_E0.7480.25
17_R97_R0.7460.25
28_R58_I0.7460.25
18_A125_R0.7430.25
122_R127_Y0.7420.25
23_W53_R0.7370.24
31_V148_V0.7330.24
66_G89_L0.7270.24
58_I61_V0.7260.24
64_I146_L0.7150.24
35_V48_I0.7120.23
99_H106_D0.7000.23
34_L56_Y0.6980.23
3_K96_V0.6980.23
8_G15_P0.6950.23
74_E118_S0.6920.23
93_A120_I0.6910.22
108_T125_R0.6900.22
51_I100_I0.6870.22
139_Y144_A0.6870.22
92_K108_T0.6850.22
97_R113_L0.6840.22
40_K57_G0.6810.22
22_K37_E0.6790.22
85_D123_L0.6780.22
90_I147_L0.6740.22
14_R62_K0.6710.22
109_A118_S0.6640.21
121_R144_A0.6610.21
29_E56_Y0.6610.21
31_V69_V0.6580.21
32_E146_L0.6580.21
22_K130_I0.6560.21
7_K125_R0.6550.21
30_E59_P0.6540.21
120_I126_Y0.6500.21
58_I67_K0.6480.21
73_L98_R0.6380.20
32_E88_N0.6370.20
23_W66_G0.6360.20
46_S70_T0.6350.20
136_E141_P0.6340.20
23_W54_D0.6140.19
9_K75_E0.6120.19
23_W59_P0.6110.19
30_E111_K0.6050.19
3_K115_E0.6040.19
20_A26_L0.6030.19
43_Y47_M0.6030.19
104_P112_G0.6030.19
9_K64_I0.5980.19
58_I121_R0.5940.19
109_A140_D0.5920.19
113_L141_P0.5920.19
7_K138_V0.5880.18
8_G122_R0.5870.18
21_P53_R0.5830.18
27_T70_T0.5810.18
57_G141_P0.5810.18
116_I131_G0.5780.18
34_L50_I0.5720.18
87_F107_K0.5690.18
33_M95_N0.5690.18
41_R111_K0.5680.18
54_D122_R0.5670.18
59_P131_G0.5640.18
128_K138_V0.5630.18
3_K11_H0.5550.17
5_R145_E0.5540.17
123_L127_Y0.5540.17
113_L139_Y0.5530.17
32_E130_I0.5500.17
26_L81_Q0.5480.17
36_E59_P0.5460.17
38_L137_W0.5460.17
41_R91_R0.5450.17
26_L56_Y0.5450.17
93_A113_L0.5440.17
14_R75_E0.5420.17
22_K25_R0.5370.17
10_S109_A0.5350.17
64_I109_A0.5350.17
14_R47_M0.5330.17
60_L65_V0.5270.16
39_A45_P0.5220.16
103_Y130_I0.5190.16
11_H30_E0.5190.16
14_R102_E0.5180.16
31_V121_R0.5180.16
20_A68_K0.5170.16
6_A95_N0.5160.16
15_P113_L0.5130.16
28_R134_P0.5120.16
38_L51_I0.5090.16
121_R145_E0.5080.16
7_K52_L0.5060.16
57_G143_K0.5040.16
46_S50_I0.5030.16
39_A95_N0.5010.15
118_S125_R0.5010.15
22_K138_V0.5000.15
10_S70_T0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j7aU 1 0.9803 100 0.109 Contact Map
3zeyG 1 0.9211 100 0.11 Contact Map
4ujpO 1 0.9803 100 0.11 Contact Map
4bpeO 1 0.9803 100 0.115 Contact Map
3j20Q 1 0.9803 100 0.301 Contact Map
5aj3O 1 0.7171 98.3 0.855 Contact Map
3bbnO 1 0.5461 97.4 0.884 Contact Map
4iylA 3 0.5329 97.4 0.884 Contact Map
4a5uB 1 0.5197 97.2 0.887 Contact Map
4rb5O 1 0.5724 97.1 0.889 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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