GREMLIN Database
Q97ZZ7 - Uncharacterized protein
UniProt: Q97ZZ7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 293 (252)
Sequences: 13749 (9433)
Seq/√Len: 594.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
7_L249_E3.2191.00
147_V151_K2.9251.00
19_S22_H2.4431.00
228_I248_V2.4391.00
100_E124_R2.4321.00
26_K243_D2.3751.00
230_S234_L2.3431.00
9_A247_F2.3271.00
27_A48_F2.3141.00
98_I111_L2.2711.00
192_K238_E2.1521.00
9_A39_A2.1501.00
153_G169_L2.1271.00
198_R201_E2.1261.00
28_K81_T2.1151.00
155_I166_S2.1061.00
240_E244_S2.0711.00
10_L207_L2.0581.00
28_K85_L2.0251.00
32_R89_G2.0231.00
109_T124_R2.0181.00
10_L209_V1.9811.00
92_H115_P1.9361.00
37_K247_F1.9351.00
43_I178_I1.9341.00
32_R88_D1.9301.00
42_V91_V1.9031.00
8_I207_L1.8981.00
175_E256_S1.8391.00
26_K29_K1.7961.00
239_A246_L1.7891.00
107_F124_R1.7781.00
193_H196_I1.7681.00
239_A244_S1.7531.00
83_I113_I1.7331.00
28_K32_R1.7311.00
177_V204_I1.6911.00
92_H112_I1.6701.00
40_K149_D1.6481.00
33_Q37_K1.6481.00
110_S154_I1.6381.00
205_P231_P1.6371.00
151_K175_E1.6341.00
86_A93_V1.6161.00
229_T235_I1.5931.00
114_S120_I1.5871.00
94_I112_I1.5861.00
84_N88_D1.5791.00
39_A247_F1.5781.00
115_P149_D1.5581.00
105_K138_S1.5561.00
100_E109_T1.5511.00
16_K22_H1.5481.00
237_K246_L1.5411.00
112_I154_I1.5401.00
152_Y176_I1.5271.00
29_K33_Q1.5241.00
94_I178_I1.5241.00
11_V42_V1.5231.00
82_L95_V1.5211.00
195_A208_I1.5131.00
109_T122_K1.5041.00
92_H148_L1.4941.00
43_I209_V1.4911.00
32_R85_L1.4831.00
94_I110_S1.4791.00
31_I42_V1.4761.00
41_L178_I1.4751.00
132_D135_L1.4701.00
207_L228_I1.4571.00
31_I93_V1.4221.00
30_L33_Q1.4211.00
27_A44_L1.4201.00
114_S118_E1.4201.00
192_K196_I1.4111.00
254_S257_K1.4021.00
92_H120_I1.3981.00
155_I179_G1.3881.00
79_T111_L1.3801.00
25_E29_K1.3621.00
205_P236_S1.3451.00
130_E134_R1.3371.00
75_P79_T1.3271.00
24_L81_T1.3251.00
166_S177_V1.3071.00
22_H25_E1.2951.00
113_I119_I1.2871.00
110_S180_T1.2821.00
85_L89_G1.2711.00
155_I165_I1.2701.00
11_V44_L1.2651.00
230_S236_S1.2571.00
214_E221_I1.2541.00
94_I154_I1.2461.00
225_P238_E1.2381.00
34_A245_L1.2381.00
80_D83_I1.2381.00
152_Y178_I1.2351.00
25_E81_T1.2321.00
31_I85_L1.2241.00
11_V245_L1.2211.00
98_I122_K1.2161.00
72_E76_G1.1971.00
31_I91_V1.1941.00
168_L172_G1.1911.00
164_E167_R1.1901.00
21_K25_E1.1851.00
40_K115_P1.1701.00
176_I207_L1.1621.00
121_G144_V1.1621.00
193_H200_I1.1531.00
80_D84_N1.1521.00
66_F69_N1.1521.00
257_K260_S1.1441.00
28_K88_D1.1391.00
22_H26_K1.1391.00
79_T113_I1.1231.00
26_K30_L1.1211.00
49_P78_N1.1091.00
166_S179_G1.1061.00
230_S254_S1.1041.00
100_E122_K1.0991.00
192_K227_F1.0871.00
13_L30_L1.0791.00
111_L122_K1.0781.00
90_E115_P1.0781.00
11_V30_L1.0691.00
24_L28_K1.0511.00
30_L245_L1.0491.00
16_K19_S1.0481.00
81_T85_L1.0451.00
225_P241_E1.0371.00
195_A229_T1.0341.00
73_K101_Q1.0281.00
7_L247_F1.0281.00
199_T206_Y1.0281.00
92_H149_D1.0261.00
33_Q36_D1.0211.00
174_S177_V1.0191.00
39_A42_V1.0181.00
81_T84_N1.0171.00
92_H114_S0.9991.00
123_Y144_V0.9981.00
107_F138_S0.9921.00
211_E215_D0.9821.00
195_A206_Y0.9811.00
82_L93_V0.9771.00
84_N87_M0.9681.00
13_L27_A0.9651.00
28_K84_N0.9591.00
112_I146_V0.9561.00
164_E267_I0.9551.00
12_H226_T0.9501.00
158_D162_S0.9471.00
158_D266_P0.9461.00
95_V113_I0.9421.00
21_K77_N0.9401.00
188_Q225_P0.9381.00
170_A204_I0.9371.00
121_G146_V0.9321.00
10_L228_I0.9301.00
72_E78_N0.9271.00
153_G174_S0.9241.00
85_L88_D0.9231.00
7_L37_K0.9171.00
167_R202_N0.9151.00
195_A227_F0.9151.00
175_E252_I0.9141.00
10_L246_L0.9131.00
148_L152_Y0.9111.00
145_N151_K0.9111.00
18_L22_H0.9071.00
32_R36_D0.9071.00
35_K91_V0.9061.00
212_S242_D0.9021.00
27_A82_L0.9011.00
145_N174_S0.8951.00
235_I238_E0.8881.00
205_P255_S0.8861.00
189_Q196_I0.8861.00
237_K248_V0.8841.00
199_T229_T0.8781.00
227_F235_I0.8771.00
193_H197_A0.8711.00
79_T119_I0.8631.00
251_S254_S0.8551.00
189_Q192_K0.8521.00
126_T165_I0.8461.00
20_R24_L0.8451.00
76_G79_T0.8421.00
253_L257_K0.8391.00
253_L256_S0.8371.00
191_I208_I0.8341.00
47_L99_L0.8311.00
147_V150_R0.8301.00
236_S248_V0.8291.00
205_P250_S0.8281.00
102_A124_R0.8271.00
34_A39_A0.8271.00
67_I70_L0.8241.00
9_A245_L0.8171.00
123_Y159_D0.8121.00
21_K81_T0.8121.00
102_A105_K0.8091.00
29_K32_R0.8091.00
255_S259_T0.8011.00
167_R171_M0.7981.00
15_L211_E0.7931.00
35_K89_G0.7901.00
14_R212_S0.7851.00
13_L48_F0.7831.00
111_L119_I0.7781.00
31_I89_G0.7771.00
100_E107_F0.7771.00
171_M267_I0.7691.00
37_K245_L0.7671.00
14_R243_D0.7671.00
36_D89_G0.7601.00
125_K157_E0.7591.00
126_T143_P0.7581.00
76_G80_D0.7581.00
79_T83_I0.7571.00
50_S75_P0.7551.00
8_I250_S0.7531.00
262_T265_E0.7521.00
64_R70_L0.7481.00
146_V152_Y0.7481.00
252_I256_S0.7461.00
205_P254_S0.7411.00
101_Q106_I0.7341.00
27_A95_V0.7341.00
24_L82_L0.7321.00
9_A34_A0.7301.00
31_I44_L0.7261.00
25_E28_K0.7231.00
155_I169_L0.7231.00
68_K101_Q0.7201.00
179_G206_Y0.7201.00
169_L174_S0.7161.00
212_S243_D0.7131.00
27_A31_I0.7111.00
83_I118_E0.7101.00
44_L48_F0.7101.00
254_S258_Q0.7091.00
78_N81_T0.7091.00
232_D258_Q0.7061.00
64_R71_A0.6981.00
160_I179_G0.6971.00
114_S149_D0.6921.00
234_L254_S0.6901.00
34_A42_V0.6891.00
10_L226_T0.6871.00
177_V206_Y0.6861.00
47_L52_N0.6861.00
6_M250_S0.6831.00
41_L94_I0.6821.00
16_K23_N0.6801.00
20_R72_E0.6791.00
13_L26_K0.6791.00
41_L92_H0.6761.00
9_A42_V0.6751.00
47_L137_I0.6731.00
83_I86_A0.6721.00
170_A202_N0.6711.00
43_I207_L0.6691.00
127_V159_D0.6691.00
160_I195_A0.6651.00
12_H224_S0.6621.00
43_I94_I0.6611.00
83_I119_I0.6581.00
64_R68_K0.6551.00
77_N80_D0.6511.00
143_P165_I0.6511.00
182_K211_E0.6491.00
65_S69_N0.6471.00
68_K71_A0.6421.00
108_L125_K0.6381.00
48_F95_V0.6351.00
170_A264_L0.6311.00
74_I111_L0.6301.00
127_V162_S0.6291.00
227_F238_E0.6291.00
74_I79_T0.6291.00
112_I152_Y0.6281.00
75_P98_I0.6241.00
16_K26_K0.6211.00
86_A89_G0.6171.00
24_L78_N0.6151.00
119_I122_K0.6141.00
108_L157_E0.6061.00
185_G221_I0.6041.00
79_T95_V0.6041.00
196_I235_I0.6001.00
183_A187_E0.5961.00
6_M41_L0.5911.00
34_A91_V0.5881.00
189_Q193_H0.5871.00
192_K225_P0.5871.00
65_S68_K0.5861.00
20_R78_N0.5851.00
33_Q245_L0.5841.00
102_A107_F0.5841.00
108_L156_A0.5811.00
34_A38_G0.5781.00
112_I148_L0.5761.00
192_K229_T0.5751.00
198_R202_N0.5721.00
188_Q223_Y0.5691.00
144_V172_G0.5681.00
66_F70_L0.5641.00
168_L171_M0.5641.00
210_G223_Y0.5621.00
10_L237_K0.5601.00
50_S99_L0.5580.99
145_N172_G0.5580.99
121_G154_I0.5570.99
14_R26_K0.5540.99
14_R211_E0.5530.99
21_K24_L0.5530.99
39_A91_V0.5520.99
161_F194_L0.5510.99
28_K89_G0.5500.99
211_E222_G0.5480.99
129_S161_F0.5480.99
123_Y140_G0.5480.99
129_S158_D0.5470.99
24_L85_L0.5440.99
143_P169_L0.5440.99
150_R175_E0.5430.99
153_G177_V0.5430.99
75_P80_D0.5410.99
196_I229_T0.5410.99
40_K90_E0.5400.99
165_I169_L0.5370.99
114_S121_G0.5370.99
100_E111_L0.5350.99
92_H152_Y0.5340.99
151_K172_G0.5330.99
183_A191_I0.5310.99
52_N137_I0.5310.99
64_R69_N0.5300.99
169_L177_V0.5300.99
49_P82_L0.5300.99
82_L85_L0.5290.99
24_L49_P0.5280.99
126_T168_L0.5270.99
194_L197_A0.5260.99
192_K235_I0.5260.99
210_G226_T0.5260.99
6_M249_E0.5250.99
96_G108_L0.5230.99
255_S258_Q0.5230.99
32_R35_K0.5180.99
99_L137_I0.5180.99
203_G258_Q0.5170.99
161_F183_A0.5150.99
41_L112_I0.5150.99
176_I205_P0.5150.99
49_P95_V0.5130.99
182_K222_G0.5120.99
252_I255_S0.5120.99
68_K72_E0.5110.99
190_V232_D0.5100.99
7_L40_K0.5090.99
90_E116_Q0.5090.99
52_N157_E0.5070.99
44_L93_V0.5070.99
175_E255_S0.5060.99
160_I194_L0.5060.99
23_N27_A0.5040.99
197_A200_I0.5030.99
6_M40_K0.5030.99
158_D161_F0.5020.99
94_I180_T0.5020.99
214_E219_E0.5010.99
30_L243_D0.5010.99
142_E145_N0.5010.99
64_R72_E0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4izuA 2 0.8532 100 0.225 Contact Map
3p8kA 2 0.8908 100 0.23 Contact Map
2vhhA 5 0.9761 100 0.232 Contact Map
2w1vA 2 0.8976 100 0.238 Contact Map
1emsA 3 0.9556 100 0.244 Contact Map
3ivzA 2 0.8669 100 0.244 Contact Map
1f89A 2 0.8737 100 0.251 Contact Map
1uf5A 4 0.9215 100 0.251 Contact Map
3wuyA 2 0.8942 100 0.263 Contact Map
2dyuA 5 0.942 100 0.269 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0097 seconds.