Q97ZZ3 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q97ZZ3 - Protein L-isoaspartate methyltransferase

UniProt:	Q97ZZ3	Sequences: MMPLNEGDPVVIWIDPKRVYISKLERGKRLDTDKGVVFYDNLIGLEYGTSLTLKTGVKAYLLKPTIQDLYSKGLKRPSQVLYPKDIGYILTTLSLNQVKTVIEAGTGSGFLTISLALSLSENAKIYTYDIREDMQKVAKFNANVLGVQDRIVFKLKDIREGIDEKEVDAIFLDMPDPWNAIPKLYESLKPSSTIIIFVPTVNQIEKTYFAMKNSGIIDIHVEELILREYQVKENAIRPRNIGIMHTGFIIRGRKSI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	256 (248)
Sequences:	1147 (705)
Seq/√Len:	44.7

HALSA - Q9HS35
SULSO - Q97ZZ3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
119_L	125_I	6.090	1.00
112_T	125_I	6.052	1.00
27_G	40_D	5.611	1.00
124_K	152_V	5.368	1.00
132_E	136_K	4.037	1.00
6_E	43_I	3.875	1.00
6_E	26_R	3.632	1.00
102_I	167_V	3.443	1.00
4_L	24_L	3.196	1.00
176_D	179_N	2.933	1.00
106_T	127_T	2.665	1.00
139_K	143_N	2.644	1.00
81_L	86_I	2.623	1.00
100_T	126_Y	2.609	1.00
210_A	213_N	2.589	1.00
168_D	189_K	2.415	1.00
25_E	28_K	2.409	1.00
46_E	49_T	2.395	1.00
221_V	250_I	2.320	1.00
92_T	220_H	2.311	1.00
116_A	150_R	2.203	1.00
135_Q	155_L	2.203	1.00
38_F	41_N	2.185	1.00
45_L	49_T	2.071	0.99
129_D	135_Q	2.024	0.99
126_Y	154_K	1.939	0.99
120_S	150_R	1.829	0.99
184_L	194_I	1.811	0.99
220_H	228_E	1.810	0.99
29_R	38_F	1.793	0.98
96_N	99_K	1.780	0.98
88_Y	92_T	1.764	0.98
115_L	125_I	1.717	0.98
88_Y	222_E	1.712	0.98
194_I	211_M	1.712	0.98
135_Q	153_F	1.676	0.98
193_T	253_R	1.671	0.97
208_Y	250_I	1.660	0.97
156_K	161_G	1.644	0.97
90_L	95_L	1.608	0.97
4_L	61_L	1.589	0.97
175_P	199_P	1.584	0.97
136_K	139_K	1.575	0.96
42_L	61_L	1.572	0.96
143_N	148_Q	1.569	0.96
24_L	42_L	1.538	0.96
181_I	184_L	1.537	0.96
103_E	112_T	1.536	0.96
12_I	59_A	1.529	0.96
132_E	155_L	1.522	0.96
20_Y	30_L	1.520	0.96
170_I	184_L	1.506	0.95
198_V	250_I	1.503	0.95
98_V	123_A	1.502	0.95
51_L	61_L	1.500	0.95
29_R	36_V	1.489	0.95
185_Y	216_I	1.482	0.95
196_I	207_T	1.482	0.95
228_E	239_R	1.481	0.95
26_R	40_D	1.463	0.95
27_G	39_Y	1.457	0.94
100_T	167_V	1.448	0.94
128_Y	164_E	1.427	0.94
104_A	172_L	1.425	0.94
204_I	221_V	1.421	0.94
211_M	252_G	1.406	0.93
104_A	158_I	1.403	0.93
113_I	145_L	1.395	0.93
225_I	242_G	1.365	0.92
188_L	192_S	1.352	0.92
81_L	89_I	1.344	0.92
197_F	247_G	1.339	0.91
95_L	101_V	1.334	0.91
111_L	247_G	1.322	0.91
86_I	90_L	1.309	0.90
158_I	180_A	1.305	0.90
116_A	151_I	1.304	0.90
112_T	142_A	1.296	0.90
181_I	210_A	1.296	0.90
223_E	227_R	1.271	0.89
12_I	42_L	1.260	0.89
102_I	170_I	1.250	0.88
195_I	251_R	1.246	0.88
178_W	206_K	1.218	0.87
4_L	47_Y	1.175	0.85
100_T	124_K	1.159	0.84
70_Y	145_L	1.157	0.84
229_Y	248_F	1.149	0.84
158_I	161_G	1.146	0.83
219_I	252_G	1.134	0.83
182_P	186_E	1.117	0.82
6_E	25_E	1.108	0.81
112_T	115_L	1.088	0.80
12_I	218_D	1.088	0.80
142_A	151_I	1.084	0.80
154_K	163_D	1.078	0.80
106_T	153_F	1.071	0.79
182_P	214_S	1.070	0.79
92_T	222_E	1.070	0.79
24_L	39_Y	1.065	0.79
93_L	193_T	1.058	0.78
168_D	192_S	1.044	0.77
82_Y	197_F	1.040	0.77
211_M	216_I	1.035	0.77
41_N	45_L	1.031	0.76
11_V	68_D	1.004	0.74
90_L	118_S	1.004	0.74
235_A	240_N	1.001	0.74
104_A	112_T	0.995	0.74
221_V	231_V	0.988	0.73
52_T	58_K	0.987	0.73
120_S	123_A	0.979	0.73
65_T	68_D	0.975	0.72
94_S	145_L	0.966	0.72
93_L	195_I	0.951	0.70
210_A	214_S	0.950	0.70
202_N	205_E	0.949	0.70
164_E	187_S	0.940	0.69
130_I	134_M	0.927	0.68
154_K	164_E	0.925	0.68
181_I	214_S	0.913	0.67
31_D	36_V	0.909	0.67
128_Y	163_D	0.908	0.67
204_I	250_I	0.898	0.66
182_P	210_A	0.896	0.66
76_R	130_I	0.894	0.66
71_S	74_L	0.893	0.65
70_Y	113_I	0.890	0.65
52_T	56_G	0.878	0.64
78_S	134_M	0.876	0.64
42_L	163_D	0.875	0.64
81_L	171_F	0.872	0.64
51_L	217_I	0.872	0.64
143_N	147_V	0.870	0.63
116_A	119_L	0.870	0.63
141_N	145_L	0.860	0.63
161_G	183_K	0.859	0.62
121_E	150_R	0.854	0.62
208_Y	219_I	0.851	0.62
42_L	51_L	0.849	0.61
95_L	169_A	0.849	0.61
198_V	202_N	0.847	0.61
134_M	141_N	0.844	0.61
27_G	212_K	0.844	0.61
154_K	167_V	0.843	0.61
174_M	198_V	0.843	0.61
127_T	153_F	0.837	0.60
70_Y	142_A	0.835	0.60
90_L	114_S	0.830	0.60
245_H	252_G	0.827	0.59
76_R	131_R	0.827	0.59
159_R	179_N	0.826	0.59
68_D	117_L	0.824	0.59
93_L	169_A	0.822	0.59
119_L	123_A	0.817	0.59
180_A	224_L	0.813	0.58
47_Y	72_K	0.813	0.58
225_I	244_M	0.812	0.58
110_F	176_D	0.809	0.58
24_L	27_G	0.803	0.57
55_T	58_K	0.800	0.57
98_V	177_P	0.798	0.57
37_V	61_L	0.796	0.57
88_Y	220_H	0.791	0.56
101_V	138_A	0.786	0.56
209_F	212_K	0.784	0.55
131_R	134_M	0.782	0.55
36_V	54_K	0.779	0.55
42_L	201_V	0.778	0.55
25_E	37_V	0.775	0.55
100_T	166_E	0.774	0.54
48_G	108_S	0.773	0.54
91_T	114_S	0.766	0.54
111_L	221_V	0.762	0.53
174_M	199_P	0.750	0.52
230_Q	239_R	0.749	0.52
95_L	209_F	0.745	0.52
129_D	134_M	0.743	0.51
74_L	120_S	0.743	0.51
164_E	186_E	0.743	0.51
78_S	82_Y	0.739	0.51
202_N	251_R	0.738	0.51
13_W	21_I	0.735	0.51
132_E	139_K	0.733	0.50
116_A	125_I	0.731	0.50
27_G	128_Y	0.728	0.50
8_D	63_K	0.725	0.50
238_P	253_R	0.725	0.50
195_I	244_M	0.724	0.50
229_Y	236_I	0.724	0.50
84_K	141_N	0.724	0.50
222_E	228_E	0.723	0.49
106_T	138_A	0.721	0.49
135_Q	139_K	0.720	0.49
97_Q	248_F	0.717	0.49
245_H	249_I	0.715	0.49
237_R	253_R	0.713	0.49
80_V	177_P	0.711	0.48
8_D	61_L	0.711	0.48
37_V	150_R	0.710	0.48
112_T	119_L	0.709	0.48
129_D	155_L	0.709	0.48
220_H	243_I	0.709	0.48
231_V	236_I	0.708	0.48
98_V	119_L	0.705	0.48
84_K	131_R	0.704	0.48
181_I	207_T	0.702	0.47
111_L	129_D	0.702	0.47
106_T	142_A	0.699	0.47
156_K	162_I	0.694	0.47
100_T	189_K	0.692	0.46
80_V	110_F	0.689	0.46
88_Y	224_L	0.688	0.46
74_L	113_I	0.684	0.46
46_E	127_T	0.681	0.45
72_K	82_Y	0.679	0.45
32_T	35_G	0.679	0.45
30_L	128_Y	0.678	0.45
112_T	116_A	0.672	0.45
102_I	162_I	0.670	0.44
89_I	111_L	0.668	0.44
185_Y	214_S	0.666	0.44
89_I	171_F	0.664	0.44
121_E	149_D	0.664	0.44
32_T	157_D	0.663	0.44
86_I	114_S	0.663	0.44
45_L	61_L	0.662	0.44
115_L	119_L	0.662	0.44
128_Y	166_E	0.662	0.44
78_S	108_S	0.658	0.43
178_W	207_T	0.657	0.43
49_T	61_L	0.656	0.43
79_Q	177_P	0.655	0.43
151_I	167_V	0.653	0.43
131_R	141_N	0.653	0.43
198_V	207_T	0.653	0.43
110_F	195_I	0.651	0.43
128_Y	180_A	0.649	0.42
158_I	172_L	0.645	0.42
103_E	125_I	0.644	0.42
106_T	151_I	0.644	0.42
90_L	112_T	0.643	0.42
79_Q	200_T	0.642	0.42
140_F	143_N	0.641	0.42
175_P	205_E	0.637	0.41
7_G	189_K	0.635	0.41
102_I	128_Y	0.633	0.41
104_A	174_M	0.632	0.41
235_A	242_G	0.631	0.41
104_A	153_F	0.630	0.41
123_A	200_T	0.630	0.41
9_P	23_K	0.629	0.40
62_L	206_K	0.623	0.40
32_T	37_V	0.623	0.40
81_L	225_I	0.621	0.40
84_K	238_P	0.619	0.40
141_N	200_T	0.619	0.40
83_P	238_P	0.618	0.39
13_W	19_V	0.617	0.39
175_P	200_T	0.617	0.39
182_P	248_F	0.615	0.39
4_L	8_D	0.614	0.39
82_Y	200_T	0.614	0.39
235_A	239_R	0.608	0.39
63_K	84_K	0.608	0.39
199_P	221_V	0.608	0.39
140_F	214_S	0.607	0.38
79_Q	161_G	0.607	0.38
181_I	216_I	0.607	0.38
28_K	37_V	0.604	0.38
206_K	212_K	0.604	0.38
82_Y	229_Y	0.601	0.38
82_Y	94_S	0.601	0.38
94_S	118_S	0.601	0.38
30_L	39_Y	0.600	0.38
191_S	237_R	0.600	0.38
67_Q	71_S	0.600	0.38
45_L	51_L	0.599	0.38
62_L	79_Q	0.599	0.38
12_I	22_S	0.598	0.38
8_D	44_G	0.597	0.38
111_L	115_L	0.597	0.38
12_I	20_Y	0.597	0.38
165_K	186_E	0.595	0.37
84_K	226_L	0.591	0.37
13_W	120_S	0.590	0.37
114_S	119_L	0.589	0.37
184_L	187_S	0.587	0.37
137_V	141_N	0.587	0.37
40_D	52_T	0.585	0.36
171_F	174_M	0.585	0.36
11_V	21_I	0.584	0.36
101_V	169_A	0.580	0.36
83_P	227_R	0.579	0.36
142_A	147_V	0.577	0.36
136_K	140_F	0.577	0.36
23_K	144_V	0.577	0.36
157_D	183_K	0.577	0.36
208_Y	231_V	0.576	0.36
47_Y	116_A	0.576	0.36
8_D	23_K	0.576	0.36
50_S	58_K	0.575	0.36
201_V	250_I	0.574	0.35
79_Q	175_P	0.572	0.35
239_R	243_I	0.571	0.35
9_P	80_V	0.571	0.35
95_L	115_L	0.565	0.35
158_I	162_I	0.565	0.35
91_T	189_K	0.561	0.34
11_V	73_G	0.560	0.34
201_V	204_I	0.558	0.34
140_F	211_M	0.558	0.34
8_D	87_G	0.556	0.34
236_I	248_F	0.554	0.34
112_T	153_F	0.552	0.34
116_A	235_A	0.552	0.34
79_Q	211_M	0.552	0.34
102_I	161_G	0.551	0.33
162_I	166_E	0.551	0.33
111_L	185_Y	0.550	0.33
99_K	111_L	0.549	0.33
19_V	128_Y	0.549	0.33
198_V	204_I	0.548	0.33
205_E	208_Y	0.548	0.33
175_P	197_F	0.546	0.33
25_E	30_L	0.545	0.33
37_V	137_V	0.545	0.33
81_L	124_K	0.537	0.32
80_V	104_A	0.535	0.32
29_R	54_K	0.532	0.32
151_I	169_A	0.531	0.32
14_I	32_T	0.531	0.32
90_L	149_D	0.531	0.32
248_F	251_R	0.529	0.32
74_L	110_F	0.529	0.32
29_R	61_L	0.529	0.32
14_I	20_Y	0.527	0.31
197_F	248_F	0.526	0.31
9_P	22_S	0.526	0.31
40_D	213_N	0.526	0.31
123_A	177_P	0.526	0.31
238_P	242_G	0.525	0.31
31_D	204_I	0.524	0.31
44_G	49_T	0.524	0.31
81_L	232_K	0.523	0.31
80_V	87_G	0.522	0.31
78_S	197_F	0.522	0.31
117_L	172_L	0.522	0.31
20_Y	59_A	0.521	0.31
92_T	251_R	0.520	0.31
22_S	213_N	0.520	0.31
19_V	51_L	0.520	0.31
86_I	106_T	0.519	0.31
80_V	165_K	0.518	0.31
5_N	46_E	0.515	0.30
128_Y	156_K	0.513	0.30
103_E	171_F	0.513	0.30
90_L	159_R	0.511	0.30
50_S	61_L	0.511	0.30
80_V	106_T	0.510	0.30
53_L	56_G	0.509	0.30
20_Y	33_D	0.507	0.30
78_S	200_T	0.507	0.30
57_V	143_N	0.506	0.30
207_T	252_G	0.505	0.30
5_N	164_E	0.505	0.30
181_I	221_V	0.504	0.30
188_L	216_I	0.503	0.29
234_N	237_R	0.502	0.29
237_R	242_G	0.502	0.29
117_L	129_D	0.501	0.29
128_Y	154_K	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1o54A	4	0.9922	100	0.433	Contact Map
1i9gA	3	0.9961	100	0.474	Contact Map
3mb5A	3	0.9844	100	0.494	Contact Map
2pwyA	3	0.9648	100	0.498	Contact Map
2b25A	3	0.9297	100	0.541	Contact Map
2yvlA	4	0.9531	100	0.589	Contact Map
1yb2A	2	0.8516	100	0.6	Contact Map
3e05A	4	0.7422	99.8	0.783	Contact Map
3ckkA	1	0.6797	99.8	0.788	Contact Map
3njrA	4	0.7109	99.8	0.796	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0083 seconds.