GREMLIN Database
RS24 - 30S ribosomal protein S24e
UniProt: Q97ZY6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 120 (110)
Sequences: 346 (197)
Seq/√Len: 18.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_I81_L5.9931.00
42_T77_S4.3951.00
64_V90_L4.2481.00
113_K117_G3.2510.99
42_T48_I2.8650.99
33_L81_L2.2850.94
65_V81_L2.2150.94
40_S47_D2.0950.91
113_K116_Q2.0230.90
15_G33_L1.9740.89
27_G93_V1.9500.88
54_Q109_K1.9190.87
46_K60_E1.7380.81
59_Q62_L1.7030.80
107_Q111_G1.6930.80
90_L102_D1.5700.74
116_Q119_K1.5050.71
24_S118_A1.5050.71
100_D105_T1.4520.68
36_Y40_S1.4440.67
52_I118_A1.4440.67
52_I56_L1.3850.64
21_M97_Y1.3630.63
84_Y93_V1.3200.60
41_G63_V1.3120.60
69_S86_S1.2700.57
35_V48_I1.2150.54
115_G118_A1.1850.52
25_V56_L1.1830.52
97_Y101_R1.1800.52
27_G89_I1.1730.51
93_V105_T1.1540.50
37_H73_G1.1520.50
18_E34_K1.1280.48
23_N28_R1.1260.48
87_R90_L1.1190.48
112_S116_Q1.1140.48
48_I87_R1.1120.47
20_D66_R1.1060.47
70_T94_E1.1040.47
40_S89_I1.1030.47
15_G50_K1.1010.47
58_S65_V1.0930.46
35_V68_I1.0810.45
102_D106_K1.0800.45
94_E98_L1.0800.45
106_K109_K1.0710.45
111_G114_G1.0660.45
34_K76_I1.0590.44
49_I90_L1.0560.44
65_V68_I1.0320.42
42_T100_D1.0180.42
57_G67_K1.0180.42
27_G77_S1.0120.41
59_Q65_V1.0060.41
30_E53_I0.9830.39
113_K118_A0.9800.39
13_A65_V0.9800.39
49_I102_D0.9730.39
21_M90_L0.9620.38
62_L65_V0.9600.38
47_D106_K0.9480.37
24_S113_K0.9440.37
84_Y116_Q0.9380.37
90_L99_L0.9190.36
54_Q60_E0.9180.36
88_E92_K0.9180.36
11_D58_S0.9090.35
66_R98_L0.8810.34
27_G33_L0.8800.33
48_I77_S0.8800.33
11_D33_L0.8680.33
68_I77_S0.8620.32
32_S51_A0.8570.32
72_Y84_Y0.8560.32
12_K89_I0.8510.32
24_S65_V0.8380.31
64_V76_I0.8360.31
44_S47_D0.8260.30
44_S110_G0.8200.30
74_A79_V0.8170.30
50_K75_G0.8150.30
64_V102_D0.8100.30
51_A55_A0.8060.29
20_D72_Y0.8050.29
13_A33_L0.8030.29
34_K78_N0.7990.29
19_R92_K0.7880.29
21_M48_I0.7850.28
65_V82_H0.7840.28
25_V72_Y0.7720.28
13_A100_D0.7660.27
35_V43_P0.7580.27
96_K99_L0.7560.27
36_Y55_A0.7520.27
51_A54_Q0.7450.26
43_P68_I0.7420.26
49_I76_I0.7330.26
48_I88_E0.7290.26
33_L93_V0.7170.25
67_K74_A0.7150.25
62_L90_L0.7080.25
15_G76_I0.7070.25
16_I82_H0.7060.25
60_E117_G0.7010.24
21_M88_E0.6990.24
65_V71_S0.6970.24
29_R58_S0.6900.24
64_V91_E0.6880.24
44_S48_I0.6800.23
45_R68_I0.6780.23
61_N65_V0.6750.23
86_S89_I0.6700.23
100_D107_Q0.6690.23
11_D15_G0.6650.23
48_I105_T0.6640.23
40_S44_S0.6630.23
61_N88_E0.6620.23
53_I59_Q0.6550.22
13_A108_K0.6540.22
39_G59_Q0.6440.22
13_A118_A0.6410.22
22_Q65_V0.6400.22
65_V87_R0.6370.21
18_E36_Y0.6340.21
71_S78_N0.6320.21
27_G109_K0.6300.21
43_P75_G0.6290.21
21_M86_S0.6220.21
93_V100_D0.6190.21
67_K78_N0.6110.20
37_H75_G0.6080.20
16_I84_Y0.6000.20
46_K49_I0.5970.20
38_M80_K0.5930.20
113_K119_K0.5890.19
12_K62_L0.5830.19
54_Q63_V0.5780.19
58_S61_N0.5740.19
62_L97_Y0.5700.19
33_L78_N0.5700.19
16_I91_E0.5610.18
87_R91_E0.5570.18
14_E22_Q0.5540.18
95_P104_G0.5500.18
103_A106_K0.5390.18
28_R83_I0.5370.18
27_G105_T0.5370.18
40_S53_I0.5370.18
17_I56_L0.5330.17
24_S27_G0.5310.17
45_R92_K0.5300.17
41_G60_E0.5270.17
80_K91_E0.5250.17
96_K113_K0.5250.17
68_I79_V0.5250.17
13_A39_G0.5200.17
50_K91_E0.5160.17
89_I107_Q0.5100.17
21_M69_S0.5100.17
13_A24_S0.5070.16
30_E72_Y0.5060.16
70_T75_G0.5050.16
82_H95_P0.5030.16
18_E26_I0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4w23Y 1 0.9167 100 0.154 Contact Map
3j60Y 1 0.975 100 0.171 Contact Map
3j7a1 1 0.9167 100 0.177 Contact Map
4ujpZ 1 0.925 100 0.184 Contact Map
4bpeP 1 0.9083 100 0.19 Contact Map
3zeyT 1 0.9167 100 0.198 Contact Map
2g1dA 1 0.8167 100 0.288 Contact Map
1ywxA 1 0.85 100 0.299 Contact Map
2v94A 1 0.8167 100 0.303 Contact Map
1xn9A 1 0.8417 100 0.303 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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