GREMLIN Database
Q97ZX5 - Uncharacterized protein
UniProt: Q97ZX5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 194 (185)
Sequences: 1912 (1540)
Seq/√Len: 113.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
151_F181_E4.3511.00
157_I162_L4.1061.00
144_I148_A3.6761.00
148_A162_L3.0671.00
172_S176_I2.9651.00
169_S172_S2.8651.00
141_I166_L2.8221.00
137_R176_I2.8161.00
148_A165_K2.7851.00
144_I162_L2.7801.00
146_L186_T2.6941.00
152_D156_R2.6031.00
157_I161_D2.5411.00
158_G161_D2.4641.00
137_R141_I2.2841.00
159_L173_L2.2631.00
153_Y174_S2.2401.00
79_L83_T2.2061.00
137_R140_Q2.1831.00
83_T100_L2.1031.00
18_F92_D1.9891.00
141_I176_I1.9391.00
168_I173_L1.9331.00
139_E143_R1.8871.00
13_L17_E1.8441.00
102_G105_E1.8191.00
77_K81_Q1.7991.00
159_L174_S1.7291.00
170_P174_S1.7211.00
185_I188_Y1.7181.00
162_L173_L1.7011.00
142_L185_I1.6431.00
58_I66_I1.6311.00
51_K54_C1.6251.00
83_T86_N1.6101.00
86_N99_I1.5961.00
176_I179_R1.5911.00
155_R178_R1.5511.00
83_T87_G1.5401.00
41_L69_N1.5261.00
50_A53_V1.5121.00
131_K188_Y1.4361.00
141_I162_L1.4091.00
182_K186_T1.3841.00
58_I61_S1.3471.00
150_F155_R1.3121.00
161_D164_K1.2960.99
105_E108_E1.2920.99
148_A157_I1.2910.99
157_I165_K1.2740.99
60_V65_F1.2580.99
175_E179_R1.2520.99
146_L151_F1.2520.99
141_I168_I1.2510.99
176_I183_N1.2320.99
149_G156_R1.2320.99
153_Y175_E1.2180.99
172_S175_E1.1880.99
146_L189_F1.1880.99
159_L176_I1.1870.99
28_L42_E1.1740.99
60_V63_Y1.1680.99
13_L18_F1.1350.99
6_V93_G1.1320.99
6_V121_R1.1280.99
137_R175_E1.1250.99
9_T12_L1.1210.98
142_L151_F1.1170.98
164_K167_N1.1090.98
151_F177_I1.0980.98
134_I180_A1.0980.98
159_L170_P1.0960.98
153_Y178_R1.0950.98
27_I41_L1.0830.98
153_Y171_S1.0820.98
108_E111_N1.0810.98
113_L118_K1.0800.98
171_S175_E1.0800.98
12_L15_F1.0670.98
58_I63_Y1.0590.98
6_V123_L1.0570.98
166_L173_L1.0540.98
141_I173_L1.0480.98
160_K170_P1.0400.98
180_A185_I1.0250.97
11_N168_I1.0090.97
110_L120_V1.0090.97
95_F123_L1.0050.97
99_I151_F1.0010.97
27_I99_I0.9990.97
25_V43_I0.9970.97
15_F18_F0.9960.97
163_A173_L0.9940.97
44_R64_K0.9900.97
111_N115_D0.9880.97
169_S178_R0.9860.97
52_Q56_E0.9790.96
67_C71_I0.9760.96
49_S52_Q0.9700.96
9_T15_F0.9700.96
151_F180_A0.9670.96
143_R147_E0.9590.96
12_L18_F0.9510.96
172_S179_R0.9400.95
153_Y176_I0.9400.95
100_L121_R0.9280.95
122_V125_V0.9270.95
172_S177_I0.9170.95
170_P179_R0.9130.95
107_R110_L0.9110.95
9_T13_L0.9110.95
61_S64_K0.9060.94
141_I180_A0.9030.94
85_M98_L0.8950.94
138_Q183_N0.8940.94
52_Q88_A0.8790.94
82_Y86_N0.8790.94
82_Y87_G0.8760.93
61_S66_I0.8750.93
150_F177_I0.8710.93
184_V188_Y0.8700.93
60_V64_K0.8580.93
185_I189_F0.8450.92
65_F68_T0.8420.92
67_C70_Y0.8420.92
125_V150_F0.8410.92
63_Y69_N0.8350.92
51_K85_M0.8280.91
172_S180_A0.8260.91
18_F93_G0.8170.91
108_E156_R0.8140.91
153_Y160_K0.8130.91
152_D182_K0.8110.91
12_L16_P0.8040.90
153_Y182_K0.8040.90
133_A187_A0.8000.90
42_E110_L0.7970.90
10_P13_L0.7950.90
39_L69_N0.7950.90
103_Y169_S0.7900.89
39_L42_E0.7850.89
144_I165_K0.7840.89
140_Q144_I0.7780.89
77_K82_Y0.7770.89
68_T73_S0.7750.88
121_R129_E0.7720.88
160_K178_R0.7700.88
13_L16_P0.7640.88
43_I50_A0.7630.88
162_L166_L0.7610.88
22_K28_L0.7580.87
130_K179_R0.7550.87
179_R184_V0.7530.87
184_V187_A0.7530.87
19_I56_E0.7510.87
150_F159_L0.7470.87
168_I171_S0.7450.86
177_I181_E0.7420.86
63_Y66_I0.7360.86
27_I32_V0.7270.85
35_E164_K0.7250.85
38_K123_L0.7120.84
14_Q17_E0.7070.83
87_G151_F0.7050.83
51_K128_A0.7050.83
34_G48_T0.7020.83
125_V171_S0.7020.83
100_L151_F0.7010.83
98_L102_G0.6970.83
25_V33_D0.6940.82
33_D109_L0.6920.82
24_T140_Q0.6870.82
28_L151_F0.6870.82
159_L172_S0.6810.81
51_K66_I0.6790.81
118_K126_V0.6770.81
10_P15_F0.6750.80
98_L109_L0.6690.80
19_I147_E0.6670.80
9_T18_F0.6660.80
150_F158_G0.6570.79
7_I15_F0.6550.78
78_I158_G0.6530.78
65_F99_I0.6510.78
179_R182_K0.6510.78
48_T168_I0.6490.78
88_A95_F0.6450.77
144_I166_L0.6420.77
59_K63_Y0.6400.77
27_I40_L0.6400.77
57_P61_S0.6340.76
76_L173_L0.6330.76
142_L189_F0.6310.76
25_V109_L0.6310.76
157_I173_L0.6300.76
66_I71_I0.6290.76
144_I157_I0.6280.76
80_S162_L0.6280.76
24_T90_T0.6250.75
8_K92_D0.6250.75
140_Q143_R0.6240.75
83_T110_L0.6230.75
89_L94_I0.6190.74
40_L159_L0.6170.74
18_F185_I0.6150.74
118_K179_R0.6140.74
149_G174_S0.6120.74
99_I109_L0.6090.73
48_T55_E0.6080.73
78_I81_Q0.6050.73
17_E50_A0.6040.73
89_L135_T0.6000.72
142_L184_V0.5980.72
110_L172_S0.5960.72
148_A173_L0.5950.72
132_D188_Y0.5950.72
9_T14_Q0.5940.71
149_G152_D0.5940.71
146_L185_I0.5930.71
19_I119_E0.5930.71
57_P128_A0.5920.71
68_T71_I0.5880.71
27_I146_L0.5880.71
114_I168_I0.5860.70
155_R158_G0.5830.70
143_R189_F0.5830.70
23_V45_G0.5820.70
14_Q94_I0.5790.70
16_P20_P0.5770.69
16_P123_L0.5750.69
47_E165_K0.5750.69
107_R130_K0.5740.69
151_F159_L0.5690.68
97_T170_P0.5640.68
139_E187_A0.5590.67
14_Q18_F0.5550.66
45_G169_S0.5480.65
90_T93_G0.5470.65
27_I72_S0.5470.65
115_D119_E0.5470.65
48_T108_E0.5450.65
38_K84_I0.5440.65
27_I162_L0.5360.64
94_I172_S0.5350.63
19_I62_K0.5340.63
106_L124_K0.5320.63
100_L109_L0.5310.63
38_K93_G0.5300.63
8_K15_F0.5300.63
17_E101_N0.5280.62
47_E91_D0.5280.62
109_L170_P0.5270.62
76_L83_T0.5260.62
102_G186_T0.5250.62
103_Y125_V0.5250.62
112_S116_I0.5240.62
28_L31_R0.5230.62
107_R111_N0.5220.62
63_Y168_I0.5200.61
101_N114_I0.5190.61
121_R152_D0.5180.61
86_N97_T0.5180.61
21_K25_V0.5150.61
49_S53_V0.5150.61
48_T52_Q0.5140.60
134_I146_L0.5140.60
17_E20_P0.5140.60
75_L109_L0.5140.60
168_I176_I0.5110.60
137_R181_E0.5100.60
57_P63_Y0.5100.60
160_K164_K0.5080.60
48_T74_E0.5080.60
166_L174_S0.5050.59
172_S188_Y0.5040.59
53_V56_E0.5010.59
15_F185_I0.5000.58
29_D59_K0.5000.58
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ku3A 1 0.3144 97.8 0.826 Contact Map
4wszA 2 0.2887 97.7 0.83 Contact Map
1s7oA 3 0.366 97.5 0.836 Contact Map
1xsvA 2 0.3608 97.4 0.839 Contact Map
1je8A 2 0.2938 97.4 0.839 Contact Map
1fseA 2 0.299 97.2 0.844 Contact Map
3cloA 2 0.9175 97.1 0.846 Contact Map
2rnjA 1 0.2887 97.1 0.846 Contact Map
3t72q 1 0.3918 97.1 0.847 Contact Map
3c57A 2 0.2629 97.1 0.848 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.008 seconds.