GREMLIN Database
Q97ZV1 - Uncharacterized protein
UniProt: Q97ZV1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 485 (371)
Sequences: 213 (151)
Seq/√Len: 7.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
76_S128_K5.1971.00
160_V210_L3.4760.93
265_S323_Y3.4330.93
68_Y133_L3.4170.93
101_K117_I3.4120.93
265_S287_E3.3060.92
264_D286_R3.2470.91
287_E323_Y3.1400.89
323_Y327_K2.9440.86
331_L340_V2.8970.85
265_S327_K2.8670.84
264_D287_E2.8500.84
264_D323_Y2.8330.83
287_E327_K2.7730.82
32_V52_L2.7690.82
313_V341_L2.6950.80
268_E327_K2.6140.78
268_E323_Y2.5410.76
265_S268_E2.5390.76
53_S62_K2.5070.75
264_D327_K2.4340.73
366_D369_K2.4160.72
106_K110_D2.4030.72
286_R327_K2.2960.68
29_A141_L2.2950.68
268_E287_E2.2870.68
16_I148_S2.2840.67
298_Y330_K2.2410.66
264_D268_E2.2280.65
339_L373_A2.2250.65
265_S302_F2.1940.64
121_Y127_E2.1880.64
74_V130_I2.1640.63
269_E273_E2.1060.61
16_I87_R2.1020.61
42_V128_K2.0970.60
152_T155_F2.0600.59
108_V274_E2.0450.58
296_R330_K2.0430.58
302_F323_Y1.9840.56
86_R90_F1.9590.55
289_E312_Y1.9430.54
133_L200_V1.9190.53
47_E342_L1.8820.52
287_E302_F1.8650.51
169_K265_S1.7890.48
11_I244_S1.7870.48
8_R60_L1.7720.47
265_S286_R1.7640.47
146_N355_T1.7400.46
173_R258_E1.7360.46
39_G46_L1.7320.46
286_R323_Y1.7250.46
59_K369_K1.7000.45
87_R255_N1.6740.43
61_V222_K1.6690.43
203_T313_V1.6620.43
35_M129_K1.6580.43
268_E286_R1.6530.43
264_D302_F1.6440.42
198_S215_P1.6420.42
182_Y318_F1.6290.42
45_I109_G1.6210.41
329_E333_N1.6100.41
32_V70_R1.6100.41
147_L176_K1.5820.40
36_F87_R1.5760.40
82_Y241_L1.5630.39
29_A64_L1.5600.39
47_E129_K1.5350.38
228_D329_E1.5190.37
104_V108_V1.5100.37
28_V333_N1.4980.37
302_F327_K1.4940.36
36_F209_N1.4830.36
70_R213_L1.4820.36
78_T203_T1.4610.35
89_L120_M1.4610.35
265_S315_I1.4560.35
234_N325_N1.4500.35
103_R276_R1.4420.35
67_I70_R1.4330.34
169_K299_F1.4230.34
161_T358_V1.4210.34
32_V64_L1.4170.34
210_L213_L1.4120.33
2_L6_L1.4050.33
115_D140_D1.4020.33
211_A227_A1.4020.33
150_L275_F1.3980.33
137_S140_D1.3900.33
3_T66_K1.3890.33
25_D28_V1.3800.32
164_V373_A1.3680.32
316_M324_V1.3640.32
213_L363_K1.3620.32
89_L276_R1.3510.31
21_A146_N1.3440.31
38_I99_N1.3230.30
23_D162_V1.3120.30
132_E325_N1.3030.30
67_I134_P1.2950.29
121_Y124_L1.2870.29
31_E114_V1.2850.29
113_H175_I1.2850.29
156_N358_V1.2830.29
242_E372_S1.2810.29
138_P370_L1.2730.29
59_K304_L1.2670.28
181_M327_K1.2630.28
179_G182_Y1.2580.28
160_V366_D1.2520.28
169_K287_E1.2470.28
112_F205_K1.2440.28
169_K323_Y1.2440.28
80_I267_I1.2370.27
266_S269_E1.2320.27
191_I334_F1.2270.27
267_I277_R1.2110.27
206_Y314_E1.2040.26
206_Y301_D1.2040.26
301_D314_E1.2040.26
43_G114_V1.1910.26
5_D138_P1.1900.26
193_I374_L1.1870.26
148_S336_Y1.1830.26
45_I324_V1.1820.26
228_D293_I1.1820.26
102_E133_L1.1750.26
37_K135_K1.1720.25
169_K362_K1.1660.25
154_I214_V1.1660.25
213_L299_F1.1570.25
193_I213_L1.1480.25
36_F59_K1.1480.25
152_T208_R1.1410.24
11_I262_R1.1360.24
72_C137_S1.1340.24
33_I135_K1.1340.24
281_D353_P1.1330.24
66_K205_K1.1260.24
214_V228_D1.1180.24
32_V133_L1.1160.24
67_I154_I1.1120.24
120_M157_A1.1090.24
142_L269_E1.1080.23
148_S201_K1.1050.23
140_D160_V1.1040.23
5_D355_T1.1030.23
44_D255_N1.0990.23
97_E293_I1.0800.23
1_M6_L1.0790.23
53_S147_L1.0740.23
267_I334_F1.0740.23
64_L222_K1.0660.22
44_D87_R1.0650.22
317_G327_K1.0590.22
176_K188_P1.0580.22
26_I72_C1.0560.22
97_E175_I1.0530.22
169_K327_K1.0500.22
284_I357_N1.0500.22
191_I269_E1.0490.22
206_Y319_W1.0430.22
314_E319_W1.0430.22
301_D319_W1.0430.22
32_V68_Y1.0350.21
116_P120_M1.0280.21
286_R302_F1.0270.21
36_F191_I1.0230.21
64_L349_E1.0220.21
149_L275_F1.0210.21
49_L121_Y1.0140.21
271_F370_L1.0140.21
11_I311_V1.0100.21
38_I125_D1.0090.21
80_I338_I1.0060.21
100_D191_I1.0030.21
201_K273_E1.0000.20
291_I334_F0.9970.20
216_F290_P0.9970.20
148_S210_L0.9950.20
228_D368_G0.9940.20
118_K142_L0.9910.20
80_I91_S0.9860.20
181_M287_E0.9810.20
34_D60_L0.9800.20
57_D205_K0.9760.20
159_K205_K0.9730.20
97_E187_N0.9710.20
72_C130_I0.9690.20
207_G211_A0.9690.20
158_Y214_V0.9680.20
93_G240_R0.9630.20
168_W188_P0.9550.19
302_F315_I0.9500.19
153_I291_I0.9490.19
213_L373_A0.9490.19
330_K338_I0.9480.19
168_W316_M0.9460.19
169_K306_K0.9450.19
171_I199_L0.9440.19
191_I337_P0.9430.19
226_I242_E0.9410.19
181_M268_E0.9400.19
175_I249_K0.9390.19
108_V354_D0.9330.19
136_F361_F0.9320.19
236_R262_R0.9320.19
64_L142_L0.9260.19
114_V349_E0.9260.19
130_I188_P0.9240.19
113_H229_I0.9220.19
5_D98_E0.9220.19
3_T304_L0.9180.18
132_E199_L0.9180.18
122_E225_I0.9160.18
162_V277_R0.9160.18
25_D202_M0.9160.18
17_I342_L0.9130.18
64_L244_S0.9100.18
102_E137_S0.9060.18
181_M265_S0.9010.18
245_S359_I0.9010.18
24_S372_S0.9000.18
84_E269_E0.8920.18
22_T25_D0.8900.18
224_T244_S0.8890.18
249_K340_V0.8890.18
92_R162_V0.8840.18
163_S339_L0.8840.18
37_K80_I0.8820.18
108_V342_L0.8790.17
46_L244_S0.8790.17
22_T242_E0.8780.17
153_I313_V0.8780.17
317_G323_Y0.8770.17
101_K115_D0.8760.17
166_D324_V0.8760.17
91_S269_E0.8710.17
10_K19_L0.8690.17
130_I184_A0.8660.17
37_K192_E0.8650.17
339_L367_I0.8630.17
26_I359_I0.8610.17
129_K263_F0.8600.17
118_K311_V0.8590.17
177_M210_L0.8570.17
315_I323_Y0.8560.17
198_S217_L0.8560.17
269_E339_L0.8540.17
343_N362_K0.8500.17
113_H304_L0.8500.17
142_L191_I0.8500.17
304_L328_I0.8500.17
179_G306_K0.8480.17
90_F312_Y0.8450.17
159_K244_S0.8450.17
149_L365_I0.8410.17
210_L237_R0.8410.17
44_D54_K0.8410.17
156_N204_E0.8400.17
137_S333_N0.8400.17
89_L156_N0.8380.17
320_T327_K0.8370.17
15_R84_E0.8360.17
102_E110_D0.8350.16
218_V339_L0.8340.16
7_A315_I0.8340.16
40_A214_V0.8340.16
220_K288_P0.8330.16
60_L144_I0.8290.16
83_I191_I0.8280.16
35_M325_N0.8260.16
200_V216_F0.8250.16
26_I34_D0.8250.16
21_A261_K0.8240.16
117_I187_N0.8240.16
367_I371_Y0.8200.16
201_K364_K0.8190.16
267_I361_F0.8160.16
161_T193_I0.8150.16
110_D245_S0.8140.16
241_L299_F0.8120.16
42_V364_K0.8070.16
93_G116_P0.8040.16
17_I110_D0.8000.16
205_K286_R0.8000.16
110_D193_I0.7990.16
195_G300_P0.7990.16
13_N49_L0.7950.16
34_D83_I0.7930.16
39_G83_I0.7920.16
292_V296_R0.7900.15
321_K326_S0.7870.15
149_L174_R0.7850.15
33_I339_L0.7840.15
41_K214_V0.7840.15
91_S140_D0.7820.15
4_S20_F0.7820.15
200_V341_L0.7800.15
265_S317_G0.7780.15
41_K87_R0.7770.15
181_M323_Y0.7730.15
191_I210_L0.7720.15
90_F339_L0.7720.15
7_A62_K0.7710.15
119_A263_F0.7700.15
50_K114_V0.7660.15
130_I204_E0.7640.15
87_R91_S0.7630.15
136_F203_T0.7620.15
112_F116_P0.7600.15
209_N326_S0.7580.15
79_K131_V0.7580.15
299_F368_G0.7570.15
66_K371_Y0.7570.15
23_D325_N0.7550.15
184_A283_N0.7520.15
106_K115_D0.7500.15
70_R100_D0.7470.15
53_S58_Y0.7460.15
373_A376_G0.7450.15
339_L359_I0.7420.15
36_F132_E0.7410.14
284_I321_K0.7410.14
263_F330_K0.7400.14
331_L363_K0.7390.14
154_I282_W0.7390.14
25_D102_E0.7380.14
92_R107_E0.7380.14
106_K332_R0.7370.14
5_D160_V0.7360.14
121_Y303_V0.7350.14
169_K264_D0.7340.14
152_T256_D0.7330.14
316_M327_K0.7300.14
244_S372_S0.7290.14
8_R19_L0.7290.14
175_I193_I0.7270.14
91_S117_I0.7240.14
52_L224_T0.7240.14
361_F365_I0.7240.14
293_I333_N0.7190.14
4_S359_I0.7160.14
214_V267_I0.7140.14
194_F198_S0.7140.14
169_K263_F0.7140.14
27_D110_D0.7140.14
74_V222_K0.7140.14
58_Y315_I0.7120.14
153_I203_T0.7120.14
315_I322_E0.7100.14
16_I80_I0.7090.14
279_I326_S0.7090.14
20_F363_K0.7080.14
148_S152_T0.7060.14
22_T146_N0.7060.14
268_E302_F0.7060.14
42_V69_L0.7050.14
36_F85_L0.7040.14
160_V221_N0.7040.14
96_L142_L0.7030.14
91_S182_Y0.7020.14
45_I205_K0.7020.14
66_K127_E0.7010.14
87_R160_V0.7000.14
265_S321_K0.6980.14
49_L315_I0.6980.14
234_N274_E0.6970.14
88_Q111_L0.6970.14
142_L229_I0.6960.14
98_E187_N0.6950.14
287_E315_I0.6940.14
48_D191_I0.6940.14
67_I148_S0.6910.14
24_S118_K0.6890.13
119_A158_Y0.6890.13
184_A358_V0.6870.13
28_V140_D0.6870.13
197_L250_L0.6860.13
199_L278_V0.6820.13
315_I362_K0.6810.13
11_I17_I0.6790.13
83_I111_L0.6790.13
35_M67_I0.6790.13
36_F133_L0.6780.13
40_A81_D0.6740.13
41_K47_E0.6730.13
146_N340_V0.6710.13
5_D245_S0.6710.13
12_E363_K0.6700.13
125_D320_T0.6700.13
47_E281_D0.6700.13
297_L367_I0.6690.13
279_I342_L0.6670.13
144_I243_L0.6660.13
138_P267_I0.6650.13
21_A270_K0.6630.13
85_L116_P0.6600.13
57_D214_V0.6580.13
53_S82_Y0.6570.13
265_S370_L0.6550.13
159_K187_N0.6540.13
214_V234_N0.6490.13
283_N354_D0.6460.13
148_S151_Q0.6460.13
103_R333_N0.6450.13
150_L214_V0.6430.13
67_I191_I0.6420.13
47_E115_D0.6420.13
155_F288_P0.6390.13
80_I263_F0.6390.13
29_A67_I0.6380.13
228_D242_E0.6380.13
108_V358_V0.6370.13
67_I128_K0.6350.12
147_L178_L0.6350.12
134_P281_D0.6320.12
132_E374_L0.6290.12
148_S213_L0.6260.12
330_K364_K0.6260.12
169_K297_L0.6260.12
265_S320_T0.6250.12
17_I374_L0.6250.12
24_S102_E0.6230.12
171_I366_D0.6230.12
100_D213_L0.6220.12
78_T260_E0.6220.12
181_M264_D0.6190.12
3_T169_K0.6180.12
149_L152_T0.6160.12
10_K137_S0.6140.12
30_K40_A0.6070.12
146_N249_K0.6070.12
87_R110_D0.6070.12
90_F153_I0.6070.12
69_L179_G0.6030.12
172_A290_P0.6030.12
140_D259_M0.6020.12
152_T320_T0.6010.12
39_G117_I0.6000.12
47_E88_Q0.5990.12
226_I372_S0.5960.12
148_S263_F0.5950.12
12_E161_T0.5940.12
133_L194_F0.5920.12
127_E261_K0.5910.12
72_C277_R0.5910.12
238_T244_S0.5890.12
190_R290_P0.5880.12
85_L120_M0.5880.12
209_N212_A0.5860.12
184_A191_I0.5850.12
33_I136_F0.5850.12
157_A227_A0.5830.12
175_I197_L0.5830.12
320_T323_Y0.5830.12
221_N293_I0.5820.12
30_K37_K0.5790.12
332_R339_L0.5780.12
234_N372_S0.5780.12
264_D321_K0.5760.11
93_G200_V0.5760.11
155_F208_R0.5760.11
244_S266_S0.5730.11
109_G139_E0.5720.11
22_T27_D0.5720.11
93_G133_L0.5700.11
125_D152_T0.5700.11
3_T6_L0.5700.11
343_N361_F0.5690.11
58_Y67_I0.5690.11
52_L274_E0.5690.11
37_K234_N0.5690.11
76_S310_K0.5680.11
213_L228_D0.5680.11
223_W327_K0.5670.11
20_F149_L0.5660.11
15_R160_V0.5660.11
11_I60_L0.5650.11
149_L288_P0.5650.11
84_E132_E0.5650.11
16_I310_K0.5640.11
92_R101_K0.5630.11
156_N194_F0.5620.11
55_I363_K0.5620.11
210_L274_E0.5620.11
83_I132_E0.5610.11
104_V242_E0.5590.11
124_L371_Y0.5590.11
185_Y198_S0.5580.11
79_K114_V0.5570.11
205_K212_A0.5560.11
120_M297_L0.5560.11
165_S275_F0.5560.11
22_T224_T0.5560.11
213_L375_R0.5550.11
122_E168_W0.5540.11
226_I240_R0.5540.11
99_N291_I0.5520.11
236_R366_D0.5510.11
186_E277_R0.5510.11
9_F222_K0.5470.11
85_L331_L0.5450.11
110_D246_G0.5450.11
52_L67_I0.5420.11
169_K268_E0.5420.11
98_E221_N0.5400.11
172_A184_A0.5400.11
39_G354_D0.5380.11
43_G185_Y0.5370.11
122_E141_L0.5360.11
104_V329_E0.5350.11
81_D103_R0.5330.11
179_G242_E0.5330.11
34_D48_D0.5330.11
112_F133_L0.5320.11
81_D113_H0.5320.11
149_L318_F0.5310.11
79_K331_L0.5310.11
1_M29_A0.5290.11
117_I201_K0.5290.11
59_K275_F0.5280.11
287_E317_G0.5280.11
199_L222_K0.5260.11
69_L203_T0.5250.11
125_D160_V0.5240.11
104_V356_L0.5220.11
347_S352_I0.5190.11
102_E107_E0.5190.11
207_G227_A0.5190.11
92_R115_D0.5190.11
95_V148_S0.5190.11
241_L349_E0.5190.11
155_F375_R0.5180.11
185_Y190_R0.5170.11
36_F349_E0.5170.11
125_D270_K0.5140.10
287_E320_T0.5140.10
103_R259_M0.5110.10
26_I110_D0.5110.10
32_V61_V0.5100.10
155_F312_Y0.5090.10
27_D81_D0.5080.10
3_T167_G0.5070.10
315_I359_I0.5040.10
72_C262_R0.5040.10
50_K281_D0.5030.10
316_M346_L0.5020.10
40_A159_K0.5020.10
76_S153_I0.5020.10
24_S273_E0.5020.10
298_Y327_K0.5010.10
34_D241_L0.5010.10
136_F164_V0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1m0dA 2 0.2433 96.7 0.959 Contact Map
4xcmA 2 0.1856 81 0.973 Contact Map
4uz3A 1 0.1876 73 0.975 Contact Map
1qpzA 2 0.1711 73 0.975 Contact Map
1jyeA 2 0.0763 69.5 0.976 Contact Map
2o20A 2 0.0763 65.3 0.977 Contact Map
4o5aA 2 0.0763 61.4 0.977 Contact Map
3ctpA 2 0.0804 60.5 0.977 Contact Map
3dbiA 2 0.0763 60.4 0.977 Contact Map
3tqnA 2 0.1979 60.3 0.977 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0114 seconds.