GREMLIN Database
Q97ZH9 - Ribonucleotide reductase (Nrd)
UniProt: Q97ZH9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 841 (677)
Sequences: 1320 (502)
Seq/√Len: 19.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
330_V771_K8.6791.00
490_A564_K5.9271.00
571_K629_E5.3821.00
327_D392_D5.2461.00
564_K629_E5.0421.00
563_Y630_R5.0271.00
528_V555_A4.7131.00
173_K491_E4.6381.00
515_E519_K4.5701.00
497_V524_V4.4181.00
226_A513_Q4.1201.00
543_D722_R3.9321.00
497_V640_V3.7281.00
690_Y716_S3.7181.00
549_Y553_Q3.5291.00
494_R568_E3.5081.00
539_G720_L3.4941.00
246_P294_A3.4891.00
595_D627_K3.4831.00
112_K179_S3.3361.00
734_M768_L3.3001.00
70_V74_L3.2601.00
567_I629_E3.2491.00
222_D225_R3.0500.99
147_R151_R3.0090.99
584_Y635_L3.0010.99
580_D585_R2.9590.99
490_A561_H2.9580.99
338_I343_T2.9570.99
563_Y635_L2.9340.99
629_E633_Y2.9080.99
182_K488_G2.8540.99
498_R572_E2.8140.99
332_G409_N2.7880.99
71_E74_L2.7730.98
209_K219_G2.6800.98
512_K515_E2.6550.98
734_M772_L2.6510.98
442_W583_L2.5610.97
624_D627_K2.5480.97
567_I633_Y2.5410.97
336_P399_S2.5410.97
332_G411_K2.5100.97
553_Q620_K2.4920.97
409_N412_S2.4920.97
622_D625_L2.4830.97
349_D397_I2.4700.97
435_I457_P2.4670.97
686_Y721_F2.4570.97
559_F563_Y2.4110.96
391_V395_L2.4040.96
334_S407_Y2.3960.96
324_Y327_D2.3930.96
715_R719_K2.3860.96
559_F641_V2.3480.96
265_M312_L2.3440.96
154_A174_F2.3350.95
457_P746_G2.3200.95
26_D32_K2.3150.95
172_D176_E2.3150.95
327_D331_K2.3030.95
334_S409_N2.2640.95
542_Y658_S2.2500.94
323_D770_W2.2410.94
336_P404_V2.2240.94
336_P407_Y2.2160.94
296_I319_V2.2160.94
159_K169_Q2.1810.93
389_I392_D2.1720.93
68_D95_R2.1650.93
768_L772_L2.1480.93
490_A560_Y2.1250.93
477_E482_A2.1240.93
41_P87_L2.1170.92
571_K633_Y2.1140.92
218_D225_R2.1120.92
366_I407_Y2.0830.92
494_R564_K2.0830.92
467_G496_G2.0760.92
541_A720_L2.0700.91
32_K63_T2.0010.90
241_F261_P1.9890.90
421_A766_Y1.9810.90
531_L551_S1.9610.89
516_D520_R1.9530.89
548_I738_A1.9490.89
147_R171_E1.9400.89
592_L630_R1.9120.88
328_A333_E1.9110.88
74_L78_S1.9020.88
567_I571_K1.9020.88
583_L596_S1.8950.87
62_D65_V1.8870.87
575_T579_Y1.8850.87
444_L578_T1.8770.87
557_F622_D1.8540.86
321_A429_L1.8530.86
208_V223_A1.8310.85
33_I36_K1.8210.85
297_E408_V1.8110.85
269_D314_N1.8000.84
265_M315_F1.7950.84
328_A336_P1.7890.84
304_T311_Q1.7880.84
115_L181_L1.7820.84
187_S284_A1.7800.84
390_T393_E1.7360.82
457_P776_G1.7270.82
267_V270_A1.6910.80
272_T285_N1.6880.80
265_M302_A1.6810.80
63_T98_N1.6630.79
262_V302_A1.6600.79
560_Y626_L1.6590.79
746_G776_G1.6580.79
36_K67_A1.6530.79
442_W596_S1.6480.79
218_D229_L1.6460.78
539_G686_Y1.6440.78
435_I776_G1.6350.78
628_G632_K1.6250.78
397_I401_E1.6110.77
63_T67_A1.6020.77
730_I768_L1.6010.76
330_V767_L1.6000.76
326_M431_F1.5940.76
490_A494_R1.5780.75
528_V558_I1.5780.75
568_E571_K1.5770.75
323_D437_R1.5650.75
71_E78_S1.5640.75
592_L595_D1.5600.75
567_I630_R1.5580.74
591_A596_S1.5580.74
685_E689_K1.5400.74
32_K94_A1.5390.74
71_E91_Y1.5370.73
456_E745_S1.5260.73
328_A399_S1.5240.73
489_L558_I1.5180.72
246_P339_N1.5160.72
568_E633_Y1.5150.72
579_Y631_L1.5130.72
78_S746_G1.5110.72
302_A312_L1.5090.72
733_V753_L1.5010.72
686_Y720_L1.4960.71
55_N77_N1.4880.71
568_E629_E1.4820.71
563_Y584_Y1.4790.70
434_T437_R1.4760.70
170_L173_K1.4710.70
200_L506_A1.4700.70
624_D628_G1.4650.70
732_H749_K1.4610.69
71_E95_R1.4510.69
67_A98_N1.4480.69
221_Y271_S1.4430.69
557_F561_H1.4410.68
100_V141_T1.4360.68
440_P459_L1.4280.68
502_N573_K1.4190.67
788_Q791_Y1.4000.66
28_F60_A1.3950.66
722_R727_V1.3920.66
221_Y267_V1.3910.66
418_V762_V1.3900.66
95_R99_H1.3870.65
476_I485_D1.3740.65
54_A58_D1.3700.64
70_V95_R1.3700.64
344_K350_H1.3690.64
157_E502_N1.3650.64
253_S275_I1.3370.62
71_E75_I1.3300.62
394_A398_A1.3270.62
751_I765_V1.3140.61
97_Y100_V1.3130.61
25_V61_I1.3100.61
29_K59_N1.2970.60
181_L653_A1.2960.60
218_D222_D1.2950.60
28_F33_I1.2890.60
564_K626_L1.2870.59
176_E180_D1.2860.59
148_R194_E1.2830.59
325_F530_G1.2830.59
625_L628_G1.2780.59
401_E404_V1.2700.58
30_L34_L1.2640.58
36_K39_S1.2500.57
534_M550_L1.2500.57
338_I404_V1.2490.57
474_F492_I1.2410.57
407_Y632_K1.2380.56
529_M646_T1.2370.56
434_T438_R1.2300.56
291_A319_V1.2250.56
78_S266_K1.2230.55
431_F766_Y1.2220.55
64_R99_H1.2190.55
476_I483_A1.2070.54
552_Y742_W1.2030.54
74_L91_Y1.2010.54
41_P74_L1.1970.54
486_W557_F1.1920.53
51_D77_N1.1890.53
200_L498_R1.1890.53
249_D341_R1.1880.53
188_P281_R1.1850.53
567_I626_L1.1840.53
658_S752_N1.1830.53
113_D143_Q1.1800.53
47_G83_F1.1770.53
53_Q57_K1.1730.52
143_Q175_Y1.1730.52
43_E90_R1.1720.52
28_F36_K1.1650.52
288_V318_S1.1640.52
632_K689_K1.1630.52
168_K171_E1.1610.51
490_A629_E1.1570.51
67_A95_R1.1540.51
575_T580_D1.1510.51
337_L408_V1.1450.50
67_A77_N1.1430.50
194_E258_A1.1400.50
305_G750_T1.1390.50
29_K32_K1.1330.50
473_K537_K1.1320.50
70_V89_K1.1280.49
187_S202_A1.1270.49
534_M554_L1.1260.49
60_A65_V1.1170.49
54_A57_K1.1150.49
175_Y179_S1.1100.48
536_I662_L1.1090.48
44_V90_R1.1040.48
100_V139_I1.1020.48
49_V74_L1.0980.47
74_L95_R1.0970.47
288_V454_G1.0920.47
188_P202_A1.0900.47
593_D742_W1.0880.47
736_Q749_K1.0880.47
63_T94_A1.0870.47
559_F594_F1.0830.47
471_L558_I1.0820.46
235_G283_G1.0820.46
51_D58_D1.0790.46
41_P60_A1.0700.46
284_A776_G1.0690.46
733_V737_A1.0640.45
67_A94_A1.0630.45
581_A585_R1.0620.45
563_Y641_V1.0590.45
230_V777_I1.0570.45
151_R168_K1.0450.44
503_V507_N1.0450.44
36_K70_V1.0450.44
542_Y732_H1.0440.44
154_A171_E1.0430.44
31_E34_L1.0420.44
789_V792_F1.0400.44
93_L97_Y1.0380.44
285_N656_S1.0370.44
53_Q67_A1.0360.44
177_M492_I1.0350.43
291_A296_I1.0340.43
28_F70_V1.0270.43
43_E63_T1.0270.43
28_F53_Q1.0260.43
487_D628_G1.0240.43
32_K36_K1.0240.43
159_K171_E1.0230.43
112_K176_E1.0220.43
109_F176_E1.0220.43
291_A413_L1.0220.43
221_Y228_A1.0210.43
32_K39_S1.0190.43
593_D597_L1.0170.42
71_E90_R1.0160.42
224_L267_V1.0140.42
23_G32_K1.0140.42
435_I746_G1.0130.42
450_T456_E1.0130.42
167_V520_R1.0120.42
38_S59_N1.0090.42
552_Y741_Q1.0070.42
404_V407_Y1.0030.42
45_T48_I1.0010.41
501_D636_R1.0010.41
501_D573_K0.9990.41
559_F657_S0.9960.41
113_D175_Y0.9910.41
70_V91_Y0.9890.41
303_K317_I0.9870.41
241_F268_F0.9810.40
152_F198_G0.9810.40
33_I37_L0.9770.40
623_F642_S0.9760.40
396_V400_K0.9730.40
630_R716_S0.9730.40
46_D83_F0.9730.40
88_A113_D0.9730.40
576_F582_R0.9710.40
447_I571_K0.9690.39
259_S303_K0.9680.39
543_D547_A0.9680.39
635_L640_V0.9660.39
628_G631_L0.9660.39
452_P779_V0.9650.39
87_L95_R0.9630.39
468_S644_A0.9610.39
289_M293_H0.9600.39
157_E498_R0.9600.39
40_V87_L0.9570.39
85_M96_I0.9570.39
348_R448_N0.9570.39
33_I67_A0.9520.38
406_K716_S0.9490.38
441_V576_F0.9490.38
258_A263_S0.9480.38
440_P457_P0.9470.38
411_K415_D0.9470.38
262_V727_V0.9450.38
539_G764_K0.9440.38
120_A542_Y0.9440.38
739_W747_T0.9430.38
25_V44_V0.9420.38
86_E96_I0.9330.37
512_K516_D0.9310.37
192_N272_T0.9290.37
346_A398_A0.9270.37
60_A63_T0.9250.37
393_E397_I0.9230.37
487_D490_A0.9220.37
297_E416_E0.9210.37
26_D63_T0.9210.37
288_V450_T0.9210.37
59_N74_L0.9200.36
74_L99_H0.9200.36
231_H276_K0.9200.36
256_G278_G0.9200.36
29_K42_D0.9190.36
109_F112_K0.9140.36
408_V553_Q0.9130.36
74_L96_I0.9130.36
560_Y622_D0.9120.36
685_E690_Y0.9100.36
143_Q179_S0.9090.36
522_R636_R0.9080.36
777_I780_Y0.9070.36
180_D412_S0.9050.36
496_G526_L0.9030.35
445_G581_A0.9030.35
122_K126_A0.9010.35
230_V649_I0.9010.35
389_I393_E0.8980.35
187_S282_R0.8950.35
450_T514_I0.8950.35
736_Q747_T0.8930.35
225_R229_L0.8890.35
266_K270_A0.8880.35
625_L629_E0.8880.35
32_K67_A0.8880.35
33_I53_Q0.8860.35
310_V314_N0.8850.34
475_V488_G0.8840.34
277_Q281_R0.8820.34
153_L503_V0.8820.34
546_D549_Y0.8820.34
250_V341_R0.8800.34
333_E409_N0.8800.34
329_V411_K0.8790.34
483_A540_I0.8790.34
73_N76_E0.8770.34
329_V337_L0.8770.34
92_V121_L0.8750.34
71_E89_K0.8740.34
28_F69_I0.8730.34
35_S51_D0.8700.34
56_V70_V0.8690.34
680_D710_N0.8680.33
297_E406_K0.8680.33
492_I495_Y0.8660.33
303_K426_D0.8660.33
418_V650_S0.8650.33
61_I69_I0.8650.33
498_R502_N0.8640.33
594_F627_K0.8640.33
769_A777_I0.8630.33
132_D137_R0.8620.33
246_P404_V0.8600.33
597_L740_Q0.8580.33
550_L554_L0.8560.33
438_R596_S0.8560.33
89_K93_L0.8550.33
222_D513_Q0.8540.33
647_G762_V0.8540.33
248_G727_V0.8540.33
51_D134_N0.8540.33
533_R655_T0.8530.33
408_V413_L0.8530.33
403_A408_V0.8520.33
523_K638_S0.8520.33
465_N504_I0.8520.33
440_P746_G0.8510.33
571_K628_G0.8500.32
96_I99_H0.8500.32
660_E750_T0.8420.32
503_V526_L0.8400.32
39_S42_D0.8380.32
180_D408_V0.8360.32
26_D34_L0.8350.32
23_G27_E0.8320.31
264_F649_I0.8290.31
485_D488_G0.8280.31
116_L146_F0.8270.31
33_I92_V0.8220.31
203_C453_C0.8210.31
204_F447_I0.8200.31
34_L53_Q0.8200.31
477_E483_A0.8190.31
174_F499_F0.8180.31
33_I70_V0.8170.31
51_D56_V0.8170.31
23_G26_D0.8160.31
28_F34_L0.8160.31
650_S657_S0.8140.30
88_A96_I0.8140.30
39_S99_H0.8140.30
91_Y100_V0.8130.30
93_L121_L0.8070.30
192_N232_Q0.8070.30
41_P99_H0.8040.30
199_I305_G0.8040.30
182_K491_E0.8040.30
74_L86_E0.8020.30
70_V78_S0.8010.30
331_K408_V0.8010.30
42_D101_F0.8000.30
471_L528_V0.7980.30
37_L88_A0.7960.30
576_F581_A0.7960.30
547_A735_H0.7950.29
662_L665_L0.7940.29
147_R172_D0.7930.29
186_N316_N0.7910.29
475_V537_K0.7890.29
96_I177_M0.7870.29
715_R718_R0.7870.29
52_V109_F0.7860.29
733_V774_I0.7860.29
29_K54_A0.7850.29
145_L194_E0.7850.29
450_T745_S0.7850.29
284_A567_I0.7840.29
626_L629_E0.7840.29
312_L315_F0.7830.29
74_L79_L0.7790.29
230_V311_Q0.7770.29
236_G453_C0.7770.29
571_K580_D0.7770.29
137_R412_S0.7750.28
151_R172_D0.7740.28
391_V399_S0.7720.28
367_Q401_E0.7700.28
61_I118_Y0.7690.28
27_E35_S0.7690.28
266_K311_Q0.7680.28
31_E53_Q0.7680.28
728_P765_V0.7670.28
26_D29_K0.7670.28
89_K96_I0.7670.28
70_V83_F0.7660.28
47_G50_N0.7660.28
114_L406_K0.7660.28
443_Y581_A0.7660.28
70_V99_H0.7640.28
71_E92_V0.7640.28
62_D68_D0.7630.28
28_F32_K0.7620.28
594_F597_L0.7620.28
111_E150_A0.7610.28
78_S84_L0.7580.28
109_F180_D0.7570.27
321_A407_Y0.7570.27
40_V67_A0.7550.27
637_N640_V0.7550.27
487_D540_I0.7540.27
68_D72_R0.7530.27
289_M299_F0.7530.27
620_K624_D0.7530.27
34_L50_N0.7520.27
571_K579_Y0.7520.27
290_H432_I0.7520.27
38_S42_D0.7520.27
91_Y96_I0.7500.27
61_I98_N0.7480.27
141_T144_M0.7470.27
333_E491_E0.7470.27
440_P639_T0.7470.27
110_D144_M0.7450.27
449_A457_P0.7450.27
251_V511_L0.7450.27
41_P44_V0.7440.27
28_F57_K0.7440.27
65_V68_D0.7430.27
159_K632_K0.7420.27
35_S38_S0.7410.27
73_N83_F0.7400.27
472_E537_K0.7390.27
458_L717_L0.7360.26
530_G533_R0.7360.26
281_R453_C0.7360.26
63_T68_D0.7350.26
72_R515_E0.7350.26
205_V523_K0.7340.26
252_A406_K0.7340.26
483_A685_E0.7340.26
567_I579_Y0.7340.26
349_D398_A0.7330.26
453_C466_L0.7330.26
331_K771_K0.7320.26
686_Y717_L0.7310.26
246_P249_D0.7310.26
50_N57_K0.7290.26
50_N54_A0.7290.26
510_P672_A0.7290.26
28_F41_P0.7280.26
503_V524_V0.7270.26
590_S593_D0.7270.26
203_C451_N0.7260.26
125_E129_L0.7260.26
681_P711_V0.7260.26
521_T578_T0.7240.26
35_S42_D0.7240.26
791_Y794_V0.7240.26
183_F467_G0.7240.26
36_K94_A0.7230.26
203_C236_G0.7210.26
71_E77_N0.7200.26
225_R513_Q0.7200.26
262_V730_I0.7190.26
36_K95_R0.7170.26
67_A70_V0.7170.26
147_R175_Y0.7160.25
454_G463_S0.7150.25
784_S788_Q0.7140.25
40_V53_Q0.7090.25
540_I650_S0.7080.25
338_I406_K0.7070.25
75_I88_A0.7070.25
59_N65_V0.7070.25
123_V311_Q0.7060.25
224_L332_G0.7040.25
42_D46_D0.7030.25
365_W368_E0.7030.25
109_F169_Q0.7020.25
332_G488_G0.7010.25
67_A71_E0.6990.25
78_S85_M0.6990.25
180_D409_N0.6980.25
543_D731_Y0.6980.25
186_N276_K0.6950.24
78_S204_F0.6940.24
430_L649_I0.6940.24
146_F181_L0.6940.24
61_I66_I0.6930.24
157_E501_D0.6920.24
203_C466_L0.6920.24
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482_A689_K0.6910.24
56_V66_I0.6900.24
302_A317_I0.6890.24
73_N77_N0.6860.24
128_Y453_C0.6860.24
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483_A538_L0.6850.24
204_F465_N0.6850.24
33_I95_R0.6850.24
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493_I679_I0.6830.24
487_D571_K0.6830.24
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37_L53_Q0.6820.24
545_V628_G0.6820.24
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169_Q632_K0.6820.24
449_A460_P0.6820.24
236_G284_A0.6800.24
127_R274_V0.6790.24
652_I659_I0.6790.24
71_E85_M0.6790.24
205_V315_F0.6790.24
240_D460_P0.6790.24
201_S251_V0.6790.24
26_D30_L0.6780.24
324_Y328_A0.6780.24
493_I771_K0.6780.24
494_R629_E0.6770.24
264_F274_V0.6770.24
75_I78_S0.6770.24
47_G70_V0.6770.24
131_K247_K0.6760.24
645_P748_S0.6750.24
210_D572_E0.6750.24
248_G685_E0.6750.24
33_I63_T0.6750.24
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300_I322_Y0.6750.24
392_D396_V0.6740.23
51_D99_H0.6730.23
46_D53_Q0.6730.23
63_T74_L0.6720.23
218_D575_T0.6720.23
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89_K95_R0.6700.23
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493_I561_H0.6490.22
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232_Q468_S0.6490.22
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563_Y567_I0.6380.22
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650_S754_R0.6380.22
451_N466_L0.6380.22
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281_R451_N0.6330.22
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326_M770_W0.6330.22
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236_G466_L0.6300.22
649_I766_Y0.6300.22
282_R647_G0.6300.22
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31_E54_A0.6280.21
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557_F621_L0.6260.21
305_G424_S0.6260.21
36_K91_Y0.6230.21
227_T239_F0.6230.21
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222_D226_A0.6220.21
90_R100_V0.6210.21
327_D334_S0.6200.21
531_L735_H0.6200.21
177_M495_Y0.6200.21
60_A577_P0.6180.21
96_I129_L0.6180.21
249_D681_P0.6170.21
140_E623_F0.6160.21
54_A625_L0.6150.21
188_P277_Q0.6150.21
63_T78_S0.6150.21
458_L744_D0.6140.21
45_T101_F0.6140.21
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154_A157_E0.6130.21
35_S632_K0.6120.21
31_E51_D0.6120.21
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580_D631_L0.6100.21
570_A634_G0.6100.21
737_A772_L0.6100.21
110_D141_T0.6100.21
730_I764_K0.6100.21
453_C645_P0.6100.21
146_F442_W0.6090.21
167_V171_E0.6090.21
330_V768_L0.6090.21
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453_C748_S0.6030.20
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43_E47_G0.6010.20
45_T52_V0.6000.20
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310_V781_R0.6000.20
301_R737_A0.5990.20
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92_V125_E0.5970.20
246_P630_R0.5970.20
232_Q518_T0.5960.20
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427_P445_G0.5940.20
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31_E38_S0.5920.20
502_N572_E0.5910.20
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50_N58_D0.5900.20
149_V190_L0.5900.20
559_F597_L0.5900.20
128_Y451_N0.5890.20
585_R590_S0.5890.20
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319_V417_I0.5870.20
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274_V655_T0.5720.19
25_V150_A0.5720.19
50_N56_V0.5710.19
184_V649_I0.5710.19
48_I66_I0.5700.19
237_T429_L0.5700.19
236_G748_S0.5700.19
276_K306_Q0.5690.19
646_T650_S0.5690.19
547_A743_N0.5690.19
269_D543_D0.5690.19
584_Y592_L0.5690.19
327_D389_I0.5680.19
510_P664_A0.5680.19
60_A71_E0.5670.19
62_D180_D0.5670.19
33_I39_S0.5660.19
288_V518_T0.5660.19
108_D331_K0.5660.19
258_A559_F0.5650.19
24_K42_D0.5640.19
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563_Y594_F0.5620.19
745_S776_G0.5620.19
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219_G222_D0.5610.19
473_K488_G0.5590.19
128_Y466_L0.5580.19
122_K297_E0.5560.19
487_D545_V0.5560.19
291_A329_V0.5560.19
175_Y292_W0.5550.18
784_S787_Q0.5550.18
328_A410_A0.5550.18
57_K111_E0.5540.18
128_Y281_R0.5540.18
463_S654_G0.5540.18
331_K631_L0.5540.18
339_N677_I0.5530.18
68_D89_K0.5530.18
32_K98_N0.5530.18
395_L399_S0.5520.18
521_T638_S0.5510.18
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34_L42_D0.5500.18
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278_G674_G0.5480.18
199_I507_N0.5480.18
253_S272_T0.5480.18
53_Q58_D0.5470.18
579_Y584_Y0.5470.18
781_R784_S0.5470.18
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524_V589_E0.5460.18
211_A256_G0.5460.18
34_L52_V0.5450.18
301_R338_I0.5450.18
47_G54_A0.5450.18
269_D310_V0.5450.18
568_E627_K0.5450.18
72_R76_E0.5450.18
456_E642_S0.5440.18
62_D524_V0.5440.18
239_F268_F0.5440.18
84_L205_V0.5440.18
178_I400_K0.5430.18
242_S347_G0.5420.18
90_R96_I0.5420.18
409_N539_G0.5420.18
543_D679_I0.5410.18
564_K625_L0.5410.18
579_Y594_F0.5410.18
63_T95_R0.5400.18
262_V303_K0.5400.18
78_S91_Y0.5400.18
463_S514_I0.5400.18
244_L302_A0.5400.18
394_A397_I0.5400.18
48_I52_V0.5390.18
327_D771_K0.5380.18
37_L631_L0.5380.18
31_E56_V0.5370.18
141_T225_R0.5370.18
203_C748_S0.5370.18
232_Q744_D0.5360.18
562_A747_T0.5360.18
186_N231_H0.5360.18
75_I84_L0.5360.18
540_I733_V0.5360.18
64_R71_E0.5350.18
430_L435_I0.5350.18
24_K159_K0.5340.18
736_Q739_W0.5340.18
309_D315_F0.5340.18
495_Y571_K0.5340.18
26_D98_N0.5330.18
82_P89_K0.5330.18
54_A716_S0.5330.18
435_I745_S0.5330.18
611_V737_A0.5320.18
469_I493_I0.5320.18
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154_A495_Y0.5300.18
146_F182_K0.5300.18
466_L645_P0.5300.18
81_Y96_I0.5300.18
266_K535_F0.5290.18
52_V64_R0.5290.18
585_R589_E0.5280.17
767_L771_K0.5280.17
733_V765_V0.5270.17
207_P240_D0.5270.17
130_L495_Y0.5270.17
24_K35_S0.5270.17
396_V399_S0.5260.17
266_K413_L0.5260.17
39_S68_D0.5260.17
647_G718_R0.5250.17
77_N100_V0.5250.17
72_R108_D0.5250.17
66_I85_M0.5240.17
77_N99_H0.5240.17
107_K632_K0.5240.17
147_R168_K0.5240.17
23_G63_T0.5240.17
126_A493_I0.5240.17
295_D781_R0.5230.17
24_K27_E0.5230.17
37_L49_V0.5230.17
29_K62_D0.5230.17
445_G465_N0.5230.17
539_G716_S0.5220.17
665_L723_T0.5210.17
47_G52_V0.5210.17
92_V99_H0.5200.17
131_K726_E0.5200.17
235_G465_N0.5200.17
307_L311_Q0.5200.17
202_A452_P0.5200.17
229_L287_G0.5200.17
150_A392_D0.5190.17
231_H518_T0.5190.17
683_F687_L0.5190.17
72_R764_K0.5180.17
176_E179_S0.5180.17
60_A628_G0.5180.17
77_N97_Y0.5180.17
39_S95_R0.5170.17
44_V47_G0.5170.17
41_P85_M0.5170.17
451_N645_P0.5170.17
169_Q173_K0.5170.17
441_V459_L0.5170.17
142_P190_L0.5160.17
143_Q147_R0.5140.17
298_D733_V0.5140.17
51_D109_F0.5140.17
32_K35_S0.5140.17
236_G645_P0.5130.17
87_L101_F0.5130.17
451_N748_S0.5120.17
476_I487_D0.5110.17
43_E73_N0.5110.17
204_F235_G0.5110.17
301_R416_E0.5110.17
540_I546_D0.5110.17
583_L591_A0.5100.17
523_K647_G0.5090.17
439_H447_I0.5090.17
466_L525_G0.5090.17
429_L766_Y0.5090.17
99_H549_Y0.5080.17
244_L426_D0.5080.17
210_D778_T0.5080.17
50_N491_E0.5080.17
650_S658_S0.5080.17
29_K51_D0.5080.17
288_V320_G0.5070.17
188_P203_C0.5070.17
146_F197_L0.5070.17
65_V628_G0.5070.17
724_A766_Y0.5060.17
86_E89_K0.5060.17
99_H107_K0.5050.17
185_P499_F0.5050.17
788_Q794_V0.5040.17
420_G651_I0.5030.17
134_N545_V0.5030.17
331_K406_K0.5030.17
590_S595_D0.5030.17
237_T448_N0.5030.17
140_E745_S0.5030.17
221_Y419_K0.5020.17
559_F593_D0.5020.17
92_V746_G0.5020.17
471_L637_N0.5010.16
68_D539_G0.5010.16
625_L632_K0.5010.16
27_E42_D0.5010.16
175_Y556_K0.5000.16
28_F54_A0.5000.16
439_H459_L0.5000.16
94_A658_S0.5000.16
30_L49_V0.5000.16
92_V95_R0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3hncA 2 0.8205 100 0.206 Contact Map
3k8tA 2 0.7087 100 0.215 Contact Map
2xapA 4 0.7931 100 0.258 Contact Map
2wghA 2 0.7289 100 0.282 Contact Map
1peqA 2 0.7146 100 0.334 Contact Map
3o0qA 2 0.6885 100 0.342 Contact Map
1l1lA 1 0.6671 100 0.518 Contact Map
4u3eA 2 0.654 99.9 0.924 Contact Map
1h7bA 2 0.5161 77.3 0.985 Contact Map
3ix3A 2 0.1807 31.6 0.988 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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