GREMLIN Database
Q97ZG8 - Uncharacterized protein
UniProt: Q97ZG8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 298 (257)
Sequences: 39155 (34262)
Seq/√Len: 2137.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
230_K234_L2.3111.00
261_K265_E2.1401.00
106_P110_E2.1071.00
46_K50_V2.1071.00
43_R46_K2.0991.00
29_K33_I2.0731.00
102_N106_P2.0671.00
199_R203_R2.0081.00
234_L238_Q2.0061.00
85_I88_I2.0051.00
99_S102_N1.9961.00
157_R160_E1.9751.00
29_K32_L1.9691.00
227_I230_K1.9681.00
74_L78_R1.9421.00
22_I25_L1.9401.00
78_R82_I1.9111.00
50_V54_T1.9021.00
199_R202_L1.8961.00
25_L29_K1.8951.00
78_R81_L1.8721.00
64_Y67_K1.8651.00
157_R161_K1.8561.00
164_L167_K1.8031.00
57_I60_V1.7881.00
220_I223_L1.7771.00
15_I18_L1.7711.00
241_L245_Q1.7691.00
71_F74_L1.7681.00
178_I182_I1.7641.00
60_V64_Y1.7541.00
113_I117_E1.7531.00
64_Y68_L1.7331.00
88_I92_F1.7281.00
106_P109_I1.7181.00
171_L175_R1.7071.00
171_L174_I1.7001.00
213_I217_S1.6891.00
185_I188_K1.6831.00
178_I181_L1.6441.00
71_F75_K1.6431.00
220_I224_N1.6241.00
192_I195_L1.5931.00
36_V39_M1.5751.00
213_I216_I1.5581.00
137_I141_E1.5551.00
241_L244_L1.5541.00
234_L237_A1.5391.00
223_L227_I1.5301.00
139_E143_K1.5261.00
164_L168_K1.5111.00
167_K171_L1.4941.00
120_L124_S1.4901.00
144_L147_A1.4651.00
43_R47_I1.4491.00
166_A170_E1.4421.00
113_I116_L1.4331.00
150_I154_K1.4331.00
206_I209_L1.4291.00
92_F96_K1.4241.00
185_I189_K1.4141.00
80_N84_I1.4131.00
22_I26_K1.3911.00
222_E226_E1.3901.00
216_I220_I1.3851.00
50_V53_L1.3821.00
153_I157_R1.3791.00
201_K205_E1.3791.00
236_E240_A1.3751.00
92_F95_V1.3721.00
152_K156_K1.3631.00
84_I88_I1.3571.00
120_L123_S1.3561.00
147_A150_I1.3531.00
109_I113_I1.3461.00
209_L213_I1.3351.00
181_L185_I1.3341.00
84_I89_R1.3341.00
243_S247_N1.3191.00
85_I89_R1.2961.00
99_S103_L1.2921.00
52_E56_Q1.2841.00
38_K42_K1.2801.00
87_Q91_D1.2781.00
174_I178_I1.2771.00
227_I231_S1.2641.00
150_I153_I1.2641.00
95_V99_S1.2491.00
160_E164_L1.2271.00
195_L199_R1.2191.00
46_K49_K1.2141.00
31_E35_K1.2011.00
115_E119_K1.1961.00
104_G108_S1.1771.00
180_T184_E1.1711.00
208_G212_E1.1701.00
21_N26_K1.1691.00
36_V40_R1.1671.00
32_L36_V1.1541.00
14_K19_K1.1511.00
206_I210_N1.1461.00
17_E21_N1.1391.00
173_T177_R1.1361.00
261_K264_I1.1311.00
225_V229_N1.1301.00
127_L131_K1.1301.00
233_E238_Q1.1271.00
88_I91_D1.1231.00
144_L148_K1.1231.00
73_Q77_R1.1221.00
112_K117_E1.1151.00
163_E168_K1.1131.00
240_A245_Q1.1121.00
35_K40_R1.1091.00
102_N105_N1.1041.00
59_V63_E1.1021.00
76_E80_N1.1001.00
107_D110_E1.1001.00
136_R141_E1.0931.00
105_N110_E1.0921.00
18_L22_I1.0841.00
211_N215_N1.0781.00
57_I61_R1.0711.00
192_I196_V1.0711.00
137_I140_L1.0701.00
84_I87_Q1.0621.00
65_K68_L1.0611.00
230_K233_E1.0541.00
232_N236_E1.0511.00
66_M70_E1.0441.00
108_S112_K1.0441.00
156_K161_K1.0411.00
170_E175_R1.0411.00
215_N219_Q1.0391.00
231_S234_L1.0371.00
35_K38_K1.0361.00
177_R180_T1.0311.00
79_K83_E1.0291.00
42_K46_K1.0251.00
49_K52_E1.0251.00
105_N108_S1.0211.00
229_N233_E1.0211.00
205_E208_G1.0101.00
67_K71_F1.0091.00
111_R115_E1.0061.00
187_E191_I1.0021.00
159_E163_E0.9991.00
256_F260_K0.9931.00
24_R28_L0.9901.00
56_Q60_V0.9821.00
94_E98_L0.9821.00
63_E66_M0.9811.00
28_L31_E0.9781.00
226_E229_N0.9761.00
257_I261_K0.9751.00
219_Q224_N0.9741.00
142_K146_D0.9681.00
45_E49_K0.9681.00
14_K17_E0.9671.00
21_N24_R0.9571.00
263_S267_K0.9541.00
202_L206_I0.9491.00
158_T161_K0.9481.00
114_R117_E0.9461.00
177_R182_I0.9431.00
101_N105_N0.9431.00
145_Q148_K0.9391.00
114_R118_W0.9381.00
91_D94_E0.9361.00
184_E189_K0.9341.00
56_Q59_V0.9331.00
23_V26_K0.9271.00
20_E24_R0.9251.00
143_K147_A0.9241.00
136_R139_E0.9221.00
49_K54_T0.9211.00
42_K45_E0.9191.00
174_I177_R0.9181.00
110_E114_R0.9171.00
135_Q139_E0.9141.00
204_D208_G0.9131.00
242_K245_Q0.9121.00
97_K101_N0.9071.00
23_V27_Q0.9041.00
51_K54_T0.9021.00
82_I86_Q0.8991.00
233_E236_E0.8981.00
112_K115_E0.8971.00
191_I194_K0.8941.00
70_E73_Q0.8911.00
56_Q61_R0.8901.00
212_E215_N0.8871.00
62_Q66_M0.8831.00
134_I138_A0.8811.00
119_K123_S0.8801.00
188_K192_I0.8761.00
169_V173_T0.8751.00
37_K40_R0.8721.00
30_L33_I0.8711.00
250_Q254_T0.8691.00
172_N176_E0.8661.00
28_L33_I0.8621.00
200_N203_R0.8561.00
98_L102_N0.8561.00
231_S235_N0.8511.00
37_K41_E0.8481.00
141_E145_Q0.8471.00
86_Q89_R0.8461.00
70_E75_K0.8451.00
72_N75_K0.8441.00
258_E261_K0.8441.00
83_E87_Q0.8421.00
194_K198_E0.8401.00
239_R243_S0.8381.00
154_K158_T0.8331.00
143_K148_K0.8331.00
228_K231_S0.8321.00
210_N214_E0.8301.00
55_Q59_V0.8271.00
205_E210_N0.8271.00
193_K197_E0.8261.00
81_L85_I0.8251.00
198_E203_R0.8241.00
218_K222_E0.8241.00
200_N204_D0.8221.00
172_N175_R0.8211.00
90_K94_E0.8191.00
170_E173_T0.8171.00
15_I19_K0.8161.00
103_L107_D0.8161.00
100_S104_G0.8141.00
181_L184_E0.8121.00
237_A241_L0.8061.00
235_N238_Q0.8061.00
69_E73_Q0.8051.00
75_K79_K0.8041.00
242_K246_E0.7921.00
16_S19_K0.7921.00
132_K136_R0.7911.00
12_Y16_S0.7891.00
219_Q222_E0.7881.00
221_E224_N0.7861.00
234_L241_L0.7851.00
255_E258_E0.7841.00
259_K263_S0.7811.00
260_K265_E0.7811.00
163_E166_A0.7791.00
151_M154_K0.7781.00
165_L169_V0.7731.00
138_A142_K0.7731.00
238_Q242_K0.7721.00
44_R47_I0.7721.00
214_E217_S0.7681.00
203_R207_N0.7661.00
107_D111_R0.7651.00
51_K55_Q0.7651.00
133_V137_I0.7621.00
158_T162_A0.7621.00
41_E45_E0.7601.00
255_E259_K0.7591.00
75_K78_R0.7511.00
191_I196_V0.7511.00
25_L28_L0.7491.00
182_I186_T0.7481.00
138_A141_E0.7481.00
34_E38_K0.7471.00
235_N239_R0.7471.00
262_K265_E0.7441.00
122_T126_T0.7441.00
260_K263_S0.7431.00
74_L77_R0.7411.00
207_N210_N0.7381.00
216_I219_Q0.7331.00
123_S126_T0.7321.00
124_S128_E0.7311.00
156_K159_E0.7271.00
145_Q149_K0.7271.00
198_E201_K0.7271.00
26_K30_L0.7251.00
186_T189_K0.7241.00
179_K182_I0.7241.00
247_N251_V0.7241.00
13_K17_E0.7191.00
155_E159_E0.7191.00
72_N76_E0.7181.00
247_N250_Q0.7171.00
184_E187_E0.7131.00
77_R80_N0.7131.00
179_K183_N0.7111.00
162_A166_A0.7071.00
60_V63_E0.7041.00
79_K82_I0.7001.00
151_M155_E0.6991.00
91_D96_K0.6961.00
39_M43_R0.6961.00
33_I37_K0.6951.00
86_Q90_K0.6931.00
226_E230_K0.6921.00
190_N194_K0.6921.00
44_R48_A0.6911.00
226_E231_S0.6881.00
246_E249_V0.6841.00
109_I112_K0.6841.00
240_A243_S0.6821.00
209_L212_E0.6811.00
189_K193_K0.6801.00
156_K160_E0.6801.00
48_A52_E0.6791.00
47_I51_K0.6771.00
163_E167_K0.6731.00
168_K172_N0.6721.00
251_V254_T0.6621.00
143_K146_D0.6621.00
165_L168_K0.6561.00
98_L103_L0.6551.00
30_L34_E0.6541.00
54_T58_N0.6531.00
127_L130_E0.6531.00
176_E180_T0.6521.00
96_K100_S0.6511.00
27_Q31_E0.6461.00
104_G107_D0.6451.00
58_N61_R0.6431.00
167_K170_E0.6421.00
108_S111_R0.6391.00
245_Q249_V0.6391.00
98_L101_N0.6371.00
188_K191_I0.6361.00
16_S20_E0.6361.00
112_K116_L0.6341.00
223_L226_E0.6331.00
19_K23_V0.6331.00
217_S221_E0.6271.00
89_R93_E0.6271.00
53_L57_I0.6241.00
212_E216_I0.6241.00
161_K165_L0.6231.00
61_R65_K0.6211.00
58_N62_Q0.6191.00
26_K29_K0.6181.00
95_V98_L0.6151.00
55_Q58_N0.6151.00
128_E131_K0.6081.00
61_R64_Y0.6071.00
20_E23_V0.6051.00
77_R82_I0.6021.00
63_E68_L0.6011.00
67_K70_E0.5951.00
42_K47_I0.5931.00
153_I156_K0.5891.00
119_K122_T0.5881.00
193_K196_V0.5881.00
228_K232_N0.5841.00
68_L72_N0.5821.00
70_E74_L0.5781.00
212_E217_S0.5751.00
262_K266_E0.5731.00
126_T129_E0.5731.00
197_E201_K0.5701.00
246_E250_Q0.5691.00
175_R179_K0.5681.00
106_P113_I0.5591.00
62_Q65_K0.5581.00
121_Q125_L0.5581.00
258_E262_K0.5521.00
186_T190_N0.5521.00
152_K155_E0.5501.00
224_N228_K0.5461.00
11_L15_I0.5401.00
118_W122_T0.5391.00
183_N187_E0.5331.00
207_N211_N0.5291.00
221_E225_V0.5251.00
32_L35_K0.5241.00
196_V200_N0.5231.00
248_P251_V0.5221.00
123_S127_L0.5211.00
18_L21_N0.5181.00
219_Q223_L0.5171.00
121_Q124_S0.5111.00
247_N252_N0.5081.00
125_L129_E0.5061.00
160_E163_E0.5061.00
82_I85_I0.5041.00
184_E188_K0.5031.00
100_S103_L0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1i84S 2 0.2114 99.3 0.363 Contact Map
1c1gA 2 0.9262 99.1 0.415 Contact Map
2dfsA 2 0.4228 96.9 0.666 Contact Map
4linA 5 0.7248 96.5 0.681 Contact Map
4uxvA 1 0.9094 95.9 0.698 Contact Map
2v71A 3 0.4966 95.6 0.705 Contact Map
4cgkA 3 0.7517 95.1 0.715 Contact Map
3ojaB 1 0.4195 94.2 0.728 Contact Map
4rsiB 1 0.3523 94.1 0.73 Contact Map
4iloA 3 0.5738 93.6 0.735 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0089 seconds.