Q97ZF3 - SULSO - GREMLIN Contacts

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Q97ZF3 - ATP-dependent helicase

UniProt:	Q97ZF3	Sequences: MLDHLDQRLRKLIEEKNWMKLTRVQEMSFEPISNGYNTLVIAPTGYGKTEAALLPILNRMLKEDVKPVTVIYITPLKALINDLLYRIDWWASRLGFLVNRKHGEVPQKEKNLRLKRIPHIIVTTPEGLEIDLDWASRFREHYKNVKWVVVDEIHELINSKRGTQLSILLERLKYFIGYDFQRIGLSATVSDEDKVAQFLFGSSERKMKIIRLNDTRNFEIKINKLGNDNSFALWKSAAEKINQLIEKPTLVFTNSRFSTERLHEELEKLGNKEIYVHHSSVSRDLKNLAEGELRNGNAKAVVCTKTLELGIHVGDIKKVIMLRPPTSVSSFLQRLGRSGHIVHGVPKGEIICFYDFDVLESLALYLSAKDGKMEKPFIDDGLDVVAREIVGMILQNQKMSIEEIFNIIRGTYIYRNLELSKLLDLVNYLVKNNIIKIEENYLKLGQGFFKIWRFNRDAKNSWGKDFSEFFSLINNDETFSLKHNGITVGEIDAVYVYKHVRANDIIRISGKFWKVLRINMHKNTIDVTPANEGEGEIPIWKGENMSKSPLIVNYIRKIMENFNEYYLTMNEIMDKNSKESIIKIFENYRKLGLKIPSRDVILVENKEDEWLYTVVIDERISNTLSHILLYLVTKKYTLNASSRSSIYGFSIKGTPVDLFKDIINMNDRKIIKIILRSILRSPLYIATLKEIQPSFGKISKINTKEDKFLIKEALRQTIKRYFTIKKTLEFIRRVREGKIKIVYTENAGSLREAIFAHAQIRPWLSDLNLTIYQALKGGAYTVNELSEILGISAKSLENKLKQLRRNNNKYKVTSFIDVDSRETRWCLYEDFIDIVKSEEYYSSFSPLNNNEIFAVDLKSGDNQVEILLKPYDLINNPEEILRKIPFNNIEEAKVREAIDTSYQFLQKYYHVGKDIIVYLLLNAIAYLQSLKYS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	933 (761)
Sequences:	1409 (827)
Seq/√Len:	30.0

ECOLI - LHR
HALSA - Q9HQA5
SULSO - Q97ZF3 Q980C0 HELX

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
419_L	423_L	5.661	1.00
380_D	421_K	5.042	1.00
405_F	419_L	4.939	1.00
560_E	598_R	4.753	1.00
36_Y	208_K	4.308	1.00
148_V	169_L	4.132	1.00
91_A	98_V	4.105	1.00
174_Y	410_G	4.011	1.00
405_F	422_L	3.866	1.00
173_K	182_R	3.734	1.00
402_E	419_L	3.708	1.00
400_S	403_E	3.567	1.00
671_I	728_L	3.466	1.00
389_I	404_I	3.393	1.00
238_A	241_I	3.385	1.00
405_F	409_R	3.381	1.00
479_F	525_I	3.359	1.00
412_Y	415_R	3.348	1.00
241_I	244_L	3.328	1.00
10_R	14_E	3.263	1.00
111_N	115_K	3.240	1.00
730_F	739_I	3.200	1.00
142_Y	145_V	3.195	1.00
163_T	414_Y	3.193	1.00
225_L	228_D	3.190	1.00
733_R	738_K	3.187	1.00
240_K	244_L	3.132	1.00
418_E	421_K	3.118	1.00
233_L	236_S	3.114	1.00
600_V	740_K	3.101	1.00
232_A	236_S	3.023	1.00
767_L	770_T	3.021	1.00
250_L	316_I	2.997	1.00
667_D	735_R	2.852	1.00
514_K	528_T	2.833	1.00
194_K	197_Q	2.767	1.00
56_I	149_V	2.748	1.00
391_G	466_F	2.697	1.00
597_S	600_V	2.697	1.00
106_P	109_E	2.653	1.00
291_G	295_N	2.644	1.00
237_A	241_I	2.597	1.00
516_L	528_T	2.593	1.00
99_N	109_E	2.588	1.00
140_E	143_K	2.569	1.00
200_F	207_M	2.560	0.99
771_I	774_A	2.521	0.99
230_S	233_L	2.501	0.99
613_T	616_I	2.489	0.99
108_K	112_L	2.487	0.99
153_I	195_V	2.485	0.99
167_I	408_I	2.475	0.99
250_L	303_C	2.469	0.99
385_V	408_I	2.450	0.99
419_L	422_L	2.450	0.99
174_Y	403_E	2.424	0.99
421_K	711_K	2.413	0.99
601_I	612_Y	2.404	0.99
241_I	245_I	2.400	0.99
35_G	181_Q	2.383	0.99
41_I	192_E	2.383	0.99
192_E	195_V	2.366	0.99
224_K	228_D	2.338	0.99
240_K	245_I	2.308	0.99
770_T	774_A	2.302	0.99
386_A	425_L	2.289	0.99
150_V	199_L	2.283	0.99
97_L	119_H	2.275	0.99
193_D	209_I	2.236	0.99
232_A	235_K	2.204	0.98
658_L	661_D	2.197	0.98
176_I	180_F	2.188	0.98
283_R	287_N	2.156	0.98
553_N	733_R	2.156	0.98
610_W	614_V	2.146	0.98
323_R	353_F	2.121	0.98
16_K	89_W	2.101	0.98
84_L	88_D	2.096	0.98
56_I	70_V	2.090	0.98
262_L	322_L	2.084	0.98
660_K	664_N	2.076	0.98
292_E	297_N	2.026	0.97
335_L	348_G	2.018	0.97
424_D	711_K	2.014	0.97
242_N	269_L	2.008	0.97
450_K	454_F	2.003	0.97
69_T	119_H	1.999	0.97
67_P	144_N	1.988	0.97
40_V	51_A	1.966	0.97
37_N	200_F	1.964	0.97
240_K	243_Q	1.957	0.97
59_R	146_K	1.957	0.97
71_I	145_V	1.955	0.97
173_K	180_F	1.942	0.96
350_I	361_S	1.941	0.96
557_K	561_N	1.938	0.96
223_N	228_D	1.930	0.96
251_V	603_V	1.919	0.96
216_R	346_P	1.917	0.96
184_G	199_L	1.898	0.96
237_A	240_K	1.882	0.96
31_P	38_T	1.879	0.96
582_I	586_E	1.871	0.96
174_Y	407_I	1.867	0.96
452_W	456_R	1.854	0.95
198_F	413_I	1.851	0.95
99_N	118_P	1.844	0.95
242_N	245_I	1.841	0.95
341_I	344_G	1.841	0.95
380_D	418_E	1.833	0.95
288_L	292_E	1.828	0.95
173_K	179_D	1.813	0.95
479_F	518_I	1.806	0.95
69_T	146_K	1.798	0.95
164_Q	168_L	1.791	0.94
324_P	360_E	1.783	0.94
505_I	512_F	1.771	0.94
359_L	581_I	1.767	0.94
237_A	245_I	1.766	0.94
557_K	598_R	1.757	0.94
194_K	198_F	1.741	0.94
148_V	172_L	1.741	0.94
616_I	730_F	1.741	0.94
88_D	92_S	1.739	0.93
381_G	414_Y	1.736	0.93
628_L	649_F	1.728	0.93
230_S	236_S	1.727	0.93
715_R	719_K	1.723	0.93
193_D	196_A	1.719	0.93
563_N	589_R	1.714	0.93
392_M	397_Q	1.713	0.93
237_A	244_L	1.695	0.93
216_R	222_I	1.693	0.93
767_L	772_Y	1.681	0.92
137_R	140_E	1.679	0.92
195_V	201_G	1.668	0.92
496_V	525_I	1.652	0.92
163_T	381_G	1.638	0.91
767_L	774_A	1.635	0.91
23_R	27_M	1.633	0.91
611_L	616_I	1.627	0.91
452_W	455_N	1.626	0.91
71_I	148_V	1.615	0.91
588_Y	749_S	1.613	0.91
9_L	58_N	1.607	0.90
610_W	615_V	1.605	0.90
392_M	399_M	1.605	0.90
768_N	771_I	1.601	0.90
767_L	771_I	1.597	0.90
216_R	225_L	1.591	0.90
28_S	40_V	1.588	0.90
399_M	404_I	1.586	0.90
216_R	339_G	1.584	0.90
73_I	128_L	1.568	0.89
392_M	404_I	1.556	0.89
549_P	616_I	1.556	0.89
389_I	425_L	1.549	0.89
393_I	455_N	1.538	0.88
113_R	131_D	1.526	0.88
239_E	269_L	1.525	0.88
16_K	93_R	1.517	0.88
549_P	729_E	1.517	0.88
611_L	614_V	1.515	0.88
729_E	732_R	1.514	0.88
515_V	518_I	1.507	0.87
403_E	406_N	1.506	0.87
553_N	729_E	1.505	0.87
401_I	423_L	1.492	0.87
195_V	198_F	1.485	0.86
744_T	748_G	1.482	0.86
366_L	370_D	1.482	0.86
223_N	226_G	1.474	0.86
382_L	417_L	1.471	0.86
145_V	148_V	1.469	0.86
53_L	74_T	1.466	0.86
245_I	300_A	1.466	0.86
366_L	554_Y	1.465	0.86
21_L	29_F	1.463	0.86
405_F	423_L	1.461	0.86
246_E	270_G	1.461	0.86
66_K	119_H	1.457	0.85
27_M	30_E	1.452	0.85
560_E	599_D	1.448	0.85
170_E	411_T	1.442	0.85
215_T	218_F	1.440	0.85
610_W	616_I	1.437	0.85
189_V	301_V	1.430	0.84
386_A	429_L	1.428	0.84
491_I	496_V	1.425	0.84
129_E	388_E	1.418	0.84
659_F	662_I	1.415	0.84
217_N	345_V	1.413	0.84
238_A	244_L	1.409	0.83
148_V	180_F	1.409	0.83
57_L	120_I	1.408	0.83
628_L	663_I	1.407	0.83
576_N	579_E	1.404	0.83
500_V	515_V	1.394	0.83
50_E	86_R	1.389	0.83
511_K	529_P	1.384	0.82
224_K	227_N	1.383	0.82
219_E	347_K	1.375	0.82
160_K	383_D	1.373	0.82
388_E	393_I	1.372	0.82
356_F	584_I	1.371	0.82
691_I	713_A	1.371	0.82
218_F	222_I	1.369	0.82
170_E	174_Y	1.366	0.81
406_N	409_R	1.363	0.81
575_K	579_E	1.361	0.81
192_E	373_M	1.354	0.81
57_L	506_I	1.348	0.81
229_N	233_L	1.344	0.80
194_K	200_F	1.340	0.80
605_N	743_Y	1.338	0.80
113_R	118_P	1.337	0.80
303_C	469_F	1.337	0.80
429_L	444_L	1.336	0.80
560_E	597_S	1.333	0.80
21_L	26_E	1.333	0.80
242_N	246_E	1.326	0.79
129_E	168_L	1.321	0.79
556_R	598_R	1.319	0.79
401_I	422_L	1.316	0.79
611_L	615_V	1.316	0.79
5_L	29_F	1.313	0.79
229_N	232_A	1.308	0.79
658_L	662_I	1.308	0.79
121_I	338_S	1.307	0.78
146_K	537_I	1.303	0.78
318_K	349_E	1.300	0.78
220_I	509_S	1.295	0.78
221_K	349_E	1.289	0.77
244_L	318_K	1.288	0.77
218_F	225_L	1.287	0.77
243_Q	246_E	1.287	0.77
131_D	141_H	1.272	0.77
251_V	300_A	1.271	0.76
771_I	775_L	1.269	0.76
549_P	726_K	1.265	0.76
770_T	775_L	1.261	0.76
393_I	399_M	1.260	0.76
600_V	742_V	1.258	0.76
427_N	431_K	1.255	0.76
281_V	289_A	1.249	0.75
237_A	242_N	1.248	0.75
62_K	149_V	1.242	0.75
401_I	446_Q	1.236	0.74
148_V	182_R	1.235	0.74
37_N	207_M	1.234	0.74
450_K	453_R	1.227	0.74
480_S	490_E	1.224	0.74
666_N	735_R	1.218	0.73
627_I	670_I	1.216	0.73
117_I	302_V	1.214	0.73
359_L	559_M	1.210	0.73
105_V	110_K	1.208	0.73
41_I	189_V	1.204	0.72
363_A	367_S	1.199	0.72
329_S	597_S	1.199	0.72
73_I	595_I	1.198	0.72
657_D	661_D	1.192	0.72
733_R	739_I	1.186	0.71
176_I	179_D	1.179	0.71
157_I	189_V	1.179	0.71
560_E	600_V	1.177	0.71
610_W	613_T	1.177	0.71
189_V	192_E	1.177	0.71
170_E	410_G	1.175	0.71
106_P	112_L	1.171	0.70
405_F	417_L	1.165	0.70
618_E	646_I	1.164	0.70
156_L	159_S	1.163	0.70
492_D	513_W	1.162	0.70
404_I	628_L	1.162	0.70
451_I	455_N	1.158	0.69
769_L	774_A	1.151	0.69
132_L	168_L	1.144	0.68
159_S	166_S	1.143	0.68
219_E	349_E	1.142	0.68
460_N	464_K	1.139	0.68
53_L	87_I	1.139	0.68
194_K	412_Y	1.133	0.68
11_K	15_E	1.130	0.67
223_N	240_K	1.121	0.67
53_L	120_I	1.121	0.67
102_H	350_I	1.121	0.67
504_D	601_I	1.118	0.67
382_L	425_L	1.117	0.67
480_S	487_T	1.115	0.66
31_P	208_K	1.109	0.66
57_L	350_I	1.107	0.66
585_F	595_I	1.103	0.66
171_R	388_E	1.102	0.65
68_V	113_R	1.102	0.65
38_T	153_I	1.097	0.65
588_Y	750_L	1.093	0.65
620_I	726_K	1.092	0.65
182_R	199_L	1.091	0.65
149_V	586_E	1.091	0.65
164_Q	466_F	1.090	0.65
6_D	58_N	1.086	0.64
222_I	225_L	1.081	0.64
58_N	62_K	1.079	0.64
63_E	69_T	1.078	0.64
165_L	700_K	1.074	0.63
53_L	86_R	1.073	0.63
301_V	307_L	1.072	0.63
120_I	347_K	1.068	0.63
7_Q	153_I	1.065	0.63
779_A	782_V	1.060	0.62
614_V	621_S	1.059	0.62
643_R	760_I	1.056	0.62
248_P	315_D	1.054	0.62
110_K	723_T	1.054	0.62
183_I	316_I	1.053	0.62
192_E	209_I	1.053	0.62
229_N	236_S	1.052	0.62
223_N	351_I	1.052	0.62
450_K	455_N	1.048	0.62
465_D	699_S	1.044	0.61
198_F	201_G	1.041	0.61
59_R	181_Q	1.039	0.61
387_R	471_S	1.038	0.61
688_L	697_K	1.035	0.61
114_L	141_H	1.035	0.61
73_I	168_L	1.023	0.60
420_S	424_D	1.023	0.60
402_E	423_L	1.021	0.59
103_G	279_S	1.021	0.59
491_I	509_S	1.021	0.59
661_D	664_N	1.020	0.59
131_D	695_F	1.020	0.59
100_R	222_I	1.020	0.59
26_E	241_I	1.018	0.59
238_A	245_I	1.016	0.59
86_R	90_W	1.010	0.59
515_V	525_I	1.006	0.58
242_N	621_S	1.006	0.58
87_I	90_W	1.006	0.58
601_I	616_I	1.003	0.58
171_R	392_M	1.001	0.58
549_P	553_N	1.000	0.58
220_I	350_I	0.999	0.58
595_I	651_I	0.999	0.58
56_I	147_W	0.999	0.58
73_I	594_K	0.999	0.58
149_V	427_N	0.992	0.57
166_S	411_T	0.991	0.57
145_V	180_F	0.990	0.57
417_L	422_L	0.988	0.57
132_L	371_G	0.986	0.57
374_E	535_G	0.985	0.57
73_I	389_I	0.983	0.57
233_L	237_A	0.983	0.57
18_W	508_I	0.979	0.56
131_D	274_I	0.979	0.56
275_Y	292_E	0.978	0.56
368_A	371_G	0.978	0.56
106_P	669_K	0.975	0.56
275_Y	285_L	0.974	0.56
222_I	365_Y	0.974	0.56
695_F	709_L	0.970	0.56
74_T	86_R	0.969	0.55
171_R	175_F	0.969	0.55
772_Y	775_L	0.966	0.55
289_A	528_T	0.965	0.55
110_K	413_I	0.964	0.55
428_Y	618_E	0.964	0.55
71_I	215_T	0.963	0.55
281_V	488_V	0.962	0.55
194_K	375_K	0.957	0.54
670_I	728_L	0.956	0.54
36_Y	729_E	0.954	0.54
7_Q	11_K	0.953	0.54
63_E	143_K	0.951	0.54
380_D	414_Y	0.949	0.54
678_I	731_I	0.946	0.54
250_L	475_N	0.944	0.53
259_T	373_M	0.943	0.53
146_K	735_R	0.941	0.53
405_F	426_V	0.938	0.53
769_L	772_Y	0.935	0.53
196_A	209_I	0.932	0.53
453_R	456_R	0.932	0.53
338_S	698_I	0.931	0.52
192_E	197_Q	0.930	0.52
195_V	199_L	0.927	0.52
328_V	368_A	0.925	0.52
612_Y	663_I	0.925	0.52
240_K	246_E	0.924	0.52
382_L	421_K	0.922	0.52
12_L	387_R	0.919	0.51
99_N	113_R	0.919	0.51
657_D	660_K	0.918	0.51
658_L	664_N	0.918	0.51
352_C	585_F	0.917	0.51
258_S	472_L	0.917	0.51
170_E	201_G	0.915	0.51
30_E	143_K	0.915	0.51
13_I	54_L	0.913	0.51
97_L	116_R	0.913	0.51
77_K	283_R	0.912	0.51
506_I	678_I	0.911	0.51
60_M	96_F	0.910	0.51
30_E	34_N	0.909	0.51
197_Q	412_Y	0.908	0.51
387_R	646_I	0.908	0.51
383_D	716_Q	0.907	0.51
279_S	527_V	0.907	0.51
11_K	16_K	0.906	0.50
265_E	268_K	0.906	0.50
304_T	542_G	0.903	0.50
350_I	365_Y	0.902	0.50
281_V	552_V	0.898	0.50
399_M	407_I	0.895	0.50
356_F	559_M	0.892	0.49
37_N	485_G	0.888	0.49
117_I	314_G	0.887	0.49
301_V	673_I	0.885	0.49
556_R	620_I	0.884	0.49
71_I	195_V	0.884	0.49
494_V	539_I	0.883	0.49
316_I	389_I	0.882	0.49
149_V	449_F	0.878	0.48
63_E	115_K	0.877	0.48
284_D	563_N	0.875	0.48
103_G	110_K	0.873	0.48
114_L	137_R	0.868	0.47
250_L	405_F	0.868	0.47
284_D	414_Y	0.867	0.47
519_N	522_K	0.867	0.47
588_Y	592_G	0.866	0.47
7_Q	10_R	0.865	0.47
451_I	454_F	0.865	0.47
219_E	251_V	0.864	0.47
585_F	729_E	0.864	0.47
184_G	328_V	0.863	0.47
768_N	772_Y	0.860	0.47
168_L	685_I	0.860	0.47
113_R	330_S	0.859	0.47
370_D	557_K	0.859	0.47
588_Y	688_L	0.858	0.47
778_G	781_T	0.858	0.47
238_A	242_N	0.856	0.46
393_I	595_I	0.855	0.46
189_V	250_L	0.853	0.46
400_S	557_K	0.853	0.46
83_L	693_P	0.853	0.46
363_A	709_L	0.851	0.46
659_F	663_I	0.851	0.46
92_S	95_G	0.849	0.46
381_G	718_I	0.848	0.46
99_N	106_P	0.847	0.46
387_R	689_K	0.844	0.46
767_L	775_L	0.844	0.46
406_N	603_V	0.843	0.45
153_I	199_L	0.843	0.45
729_E	733_R	0.842	0.45
323_R	673_I	0.842	0.45
160_K	716_Q	0.840	0.45
13_I	123_T	0.839	0.45
563_N	597_S	0.838	0.45
95_G	249_T	0.837	0.45
480_S	524_T	0.834	0.45
648_G	754_I	0.833	0.45
10_R	603_V	0.833	0.45
594_K	742_V	0.830	0.44
74_T	90_W	0.829	0.44
525_I	695_F	0.828	0.44
35_G	146_K	0.828	0.44
416_N	725_K	0.827	0.44
630_Y	723_T	0.826	0.44
471_S	646_I	0.824	0.44
388_E	391_G	0.822	0.44
223_N	227_N	0.822	0.44
144_N	426_V	0.819	0.44
193_D	664_N	0.817	0.43
633_T	677_S	0.817	0.43
259_T	698_I	0.816	0.43
60_M	70_V	0.815	0.43
547_K	552_V	0.815	0.43
32_I	38_T	0.815	0.43
398_K	456_R	0.815	0.43
122_V	582_I	0.813	0.43
239_E	243_Q	0.812	0.43
709_L	780_Y	0.812	0.43
250_L	344_G	0.811	0.43
46_Y	78_A	0.811	0.43
223_N	397_Q	0.810	0.43
40_V	192_E	0.809	0.43
127_G	130_I	0.807	0.43
68_V	141_H	0.803	0.42
53_L	90_W	0.797	0.42
150_V	399_M	0.796	0.42
167_I	414_Y	0.795	0.42
257_F	506_I	0.795	0.42
367_S	554_Y	0.794	0.42
158_N	329_S	0.794	0.42
158_N	651_I	0.793	0.42
562_F	585_F	0.792	0.41
251_V	579_E	0.791	0.41
332_L	373_M	0.789	0.41
284_D	532_E	0.788	0.41
30_E	33_S	0.787	0.41
359_L	746_N	0.786	0.41
710_I	714_L	0.786	0.41
514_K	533_G	0.786	0.41
382_L	715_R	0.786	0.41
553_N	598_R	0.785	0.41
144_N	589_R	0.785	0.41
274_I	300_A	0.783	0.41
612_Y	649_F	0.783	0.41
110_K	209_I	0.781	0.41
197_Q	200_F	0.780	0.41
375_K	550_L	0.779	0.40
54_L	91_A	0.778	0.40
95_G	418_E	0.778	0.40
395_Q	398_K	0.777	0.40
115_K	496_V	0.776	0.40
60_M	65_V	0.776	0.40
167_I	411_T	0.776	0.40
300_A	360_E	0.775	0.40
365_Y	414_Y	0.775	0.40
201_G	249_T	0.774	0.40
645_S	648_G	0.774	0.40
78_A	537_I	0.774	0.40
32_I	147_W	0.773	0.40
613_T	747_A	0.773	0.40
11_K	420_S	0.773	0.40
482_K	524_T	0.773	0.40
244_L	349_E	0.773	0.40
168_L	388_E	0.772	0.40
410_G	750_L	0.772	0.40
366_L	558_I	0.772	0.40
62_K	724_I	0.770	0.40
194_K	377_F	0.769	0.40
347_K	351_I	0.769	0.40
469_F	699_S	0.769	0.40
435_I	438_E	0.768	0.40
60_M	603_V	0.767	0.40
321_M	443_K	0.767	0.40
267_E	274_I	0.766	0.39
546_S	619_R	0.764	0.39
231_F	236_S	0.763	0.39
463_G	467_S	0.763	0.39
284_D	595_I	0.763	0.39
99_N	110_K	0.762	0.39
502_A	624_L	0.762	0.39
127_G	132_L	0.761	0.39
645_S	713_A	0.761	0.39
468_E	587_N	0.760	0.39
192_E	198_F	0.760	0.39
70_V	380_D	0.759	0.39
678_I	722_F	0.758	0.39
221_K	300_A	0.757	0.39
600_V	738_K	0.757	0.39
157_I	195_V	0.757	0.39
80_I	131_D	0.756	0.39
114_L	135_A	0.755	0.39
201_G	205_R	0.754	0.39
57_L	284_D	0.754	0.39
472_L	618_E	0.754	0.39
409_R	530_A	0.754	0.39
150_V	660_K	0.753	0.39
659_F	664_N	0.753	0.39
259_T	276_V	0.752	0.38
153_I	665_M	0.752	0.38
649_F	739_I	0.752	0.38
110_K	340_H	0.751	0.38
127_G	539_I	0.750	0.38
526_D	750_L	0.750	0.38
623_T	722_F	0.749	0.38
140_E	243_Q	0.748	0.38
605_N	741_I	0.748	0.38
409_R	557_K	0.747	0.38
512_F	532_E	0.747	0.38
668_R	706_D	0.746	0.38
244_L	351_I	0.746	0.38
283_R	746_N	0.746	0.38
107_Q	727_T	0.746	0.38
233_L	244_L	0.745	0.38
116_R	735_R	0.745	0.38
241_I	249_T	0.745	0.38
327_S	547_K	0.745	0.38
113_R	141_H	0.745	0.38
303_C	771_I	0.744	0.38
127_G	306_T	0.743	0.38
574_D	577_S	0.742	0.38
170_E	182_R	0.742	0.38
34_N	208_K	0.742	0.38
73_I	211_R	0.742	0.38
212_L	222_I	0.740	0.38
143_K	597_S	0.740	0.38
38_T	207_M	0.740	0.38
397_Q	595_I	0.740	0.38
546_S	552_V	0.740	0.38
84_L	122_V	0.739	0.37
420_S	740_K	0.737	0.37
385_V	417_L	0.737	0.37
164_Q	472_L	0.736	0.37
363_A	558_I	0.734	0.37
37_N	173_K	0.734	0.37
99_N	300_A	0.734	0.37
115_K	127_G	0.734	0.37
275_Y	289_A	0.732	0.37
733_R	736_E	0.732	0.37
629_L	651_I	0.731	0.37
12_L	471_S	0.731	0.37
471_S	689_K	0.731	0.37
648_G	751_R	0.731	0.37
408_I	419_L	0.730	0.37
59_R	63_E	0.730	0.37
491_I	681_S	0.730	0.37
212_L	215_T	0.729	0.37
210_I	222_I	0.729	0.37
500_V	504_D	0.727	0.37
239_E	242_N	0.727	0.37
602_L	742_V	0.727	0.37
15_E	64_D	0.727	0.37
92_S	563_N	0.727	0.37
428_Y	639_N	0.727	0.37
578_K	581_I	0.727	0.37
665_M	731_I	0.727	0.37
474_N	494_V	0.726	0.37
507_R	537_I	0.726	0.37
54_L	90_W	0.725	0.36
168_L	172_L	0.725	0.36
196_A	200_F	0.724	0.36
168_L	470_F	0.724	0.36
237_A	243_Q	0.724	0.36
115_K	418_E	0.724	0.36
211_R	216_R	0.723	0.36
73_I	600_V	0.723	0.36
615_V	621_S	0.723	0.36
73_I	566_Y	0.723	0.36
551_I	705_E	0.723	0.36
218_F	642_S	0.723	0.36
149_V	295_N	0.722	0.36
167_I	385_V	0.721	0.36
167_I	384_V	0.720	0.36
384_V	472_L	0.719	0.36
767_L	773_Q	0.718	0.36
27_M	66_K	0.717	0.36
257_F	261_R	0.716	0.36
408_I	425_L	0.716	0.36
217_N	220_I	0.715	0.36
34_N	740_K	0.714	0.36
391_G	470_F	0.713	0.36
381_G	412_Y	0.711	0.35
7_Q	595_I	0.711	0.35
306_T	491_I	0.711	0.35
670_I	731_I	0.710	0.35
483_H	488_V	0.710	0.35
32_I	181_Q	0.710	0.35
373_M	486_I	0.710	0.35
540_W	543_E	0.708	0.35
199_L	209_I	0.708	0.35
303_C	684_Y	0.707	0.35
302_V	382_L	0.706	0.35
36_Y	206_K	0.706	0.35
292_E	739_I	0.705	0.35
400_S	451_I	0.705	0.35
267_E	469_F	0.703	0.35
418_E	512_F	0.703	0.35
329_S	485_G	0.702	0.35
627_I	673_I	0.702	0.35
35_G	386_A	0.700	0.35
212_L	514_K	0.699	0.35
581_I	584_I	0.699	0.35
451_I	456_R	0.697	0.34
62_K	210_I	0.697	0.34
293_L	390_V	0.695	0.34
145_V	392_M	0.694	0.34
281_V	317_K	0.693	0.34
548_S	551_I	0.693	0.34
115_K	194_K	0.692	0.34
586_E	745_E	0.692	0.34
148_V	224_K	0.692	0.34
73_I	143_K	0.689	0.34
658_L	663_I	0.689	0.34
50_E	471_S	0.688	0.34
294_R	314_G	0.688	0.34
163_T	338_S	0.687	0.34
197_Q	369_K	0.687	0.34
317_K	338_S	0.686	0.34
202_S	205_R	0.686	0.34
11_K	595_I	0.685	0.34
728_L	732_R	0.685	0.34
84_L	695_F	0.685	0.34
684_Y	780_Y	0.683	0.33
73_I	399_M	0.682	0.33
667_D	728_L	0.681	0.33
361_S	535_G	0.681	0.33
304_T	513_W	0.680	0.33
182_R	282_S	0.679	0.33
60_M	64_D	0.678	0.33
299_K	386_A	0.677	0.33
129_E	164_Q	0.676	0.33
653_G	670_I	0.676	0.33
26_E	174_Y	0.676	0.33
248_P	492_D	0.674	0.33
573_M	577_S	0.674	0.33
300_A	344_G	0.673	0.33
674_I	677_S	0.672	0.33
402_E	453_R	0.672	0.33
78_A	555_I	0.671	0.33
135_A	138_F	0.671	0.33
284_D	674_I	0.670	0.32
277_H	306_T	0.669	0.32
107_Q	115_K	0.669	0.32
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149_V	156_L	0.668	0.32
414_Y	418_E	0.668	0.32
54_L	505_I	0.668	0.32
233_L	506_I	0.667	0.32
90_W	160_K	0.665	0.32
34_N	736_E	0.665	0.32
36_Y	62_K	0.664	0.32
552_V	555_I	0.663	0.32
105_V	118_P	0.662	0.32
320_I	726_K	0.662	0.32
107_Q	111_N	0.661	0.32
387_R	504_D	0.661	0.32
607_E	695_F	0.660	0.32
273_E	407_I	0.660	0.32
30_E	197_Q	0.660	0.32
631_L	665_M	0.658	0.32
35_G	706_D	0.657	0.32
220_I	253_T	0.657	0.32
694_S	712_E	0.657	0.32
96_F	658_L	0.656	0.32
82_D	87_I	0.655	0.31
471_S	695_F	0.655	0.31
704_K	709_L	0.655	0.31
117_I	677_S	0.655	0.31
306_T	368_A	0.654	0.31
81_N	135_A	0.654	0.31
9_L	132_L	0.653	0.31
237_A	253_T	0.653	0.31
164_Q	303_C	0.652	0.31
330_S	360_E	0.652	0.31
89_W	93_R	0.652	0.31
23_R	370_D	0.651	0.31
708_F	748_G	0.651	0.31
620_I	730_F	0.651	0.31
313_V	495_Y	0.650	0.31
57_L	178_Y	0.650	0.31
303_C	539_I	0.650	0.31
206_K	328_V	0.649	0.31
608_D	718_I	0.649	0.31
133_D	470_F	0.648	0.31
250_L	545_M	0.648	0.31
176_I	241_I	0.647	0.31
246_E	671_I	0.647	0.31
409_R	563_N	0.647	0.31
113_R	469_F	0.646	0.31
207_M	555_I	0.645	0.31
120_I	512_F	0.645	0.31
326_T	441_Y	0.645	0.31
99_N	112_L	0.644	0.31
283_R	422_L	0.643	0.31
233_L	238_A	0.642	0.31
542_G	615_V	0.640	0.30
307_L	318_K	0.640	0.30
464_K	468_E	0.640	0.30
40_V	717_T	0.639	0.30
137_R	559_M	0.639	0.30
78_A	314_G	0.638	0.30
66_K	150_V	0.638	0.30
171_R	407_I	0.638	0.30
39_L	185_L	0.638	0.30
102_H	507_R	0.637	0.30
43_P	76_L	0.637	0.30
515_V	522_K	0.636	0.30
32_I	183_I	0.636	0.30
665_M	670_I	0.636	0.30
169_L	199_L	0.635	0.30
107_Q	582_I	0.635	0.30
77_K	103_G	0.634	0.30
41_I	113_R	0.634	0.30
86_R	471_S	0.634	0.30
282_S	403_E	0.633	0.30
71_I	595_I	0.633	0.30
494_V	497_Y	0.632	0.30
143_K	735_R	0.632	0.30
400_S	422_L	0.629	0.30
30_E	208_K	0.629	0.30
149_V	332_L	0.629	0.30
150_V	628_L	0.628	0.30
284_D	392_M	0.627	0.30
132_L	501_R	0.624	0.29
601_I	726_K	0.623	0.29
564_E	738_K	0.623	0.29
57_L	112_L	0.623	0.29
98_V	422_L	0.623	0.29
74_T	155_E	0.621	0.29
284_D	423_L	0.621	0.29
295_N	557_K	0.620	0.29
565_Y	741_I	0.620	0.29
401_I	426_V	0.619	0.29
42_A	339_G	0.619	0.29
227_N	738_K	0.619	0.29
220_I	349_E	0.618	0.29
104_E	286_K	0.616	0.29
491_I	525_I	0.616	0.29
632_V	653_G	0.616	0.29
231_F	237_A	0.616	0.29
241_I	683_L	0.616	0.29
451_I	706_D	0.615	0.29
425_L	650_S	0.613	0.29
110_K	689_K	0.613	0.29
164_Q	603_V	0.613	0.29
217_N	221_K	0.613	0.29
719_K	725_K	0.612	0.29
28_S	52_A	0.612	0.29
56_I	210_I	0.612	0.29
645_S	757_H	0.611	0.29
386_A	496_V	0.609	0.28
687_T	716_Q	0.609	0.28
280_S	425_L	0.609	0.28
594_K	740_K	0.608	0.28
281_V	505_I	0.608	0.28
193_D	685_I	0.607	0.28
176_I	236_S	0.607	0.28
297_N	660_K	0.607	0.28
512_F	530_A	0.607	0.28
555_I	632_V	0.607	0.28
29_F	58_N	0.606	0.28
145_V	469_F	0.606	0.28
236_S	244_L	0.605	0.28
540_W	712_E	0.605	0.28
316_I	501_R	0.605	0.28
347_K	418_E	0.605	0.28
87_I	96_F	0.604	0.28
316_I	634_K	0.604	0.28
251_V	406_N	0.603	0.28
492_D	543_E	0.603	0.28
159_S	478_T	0.603	0.28
40_V	261_R	0.602	0.28
553_N	557_K	0.602	0.28
77_K	285_L	0.601	0.28
578_K	582_I	0.601	0.28
67_P	156_L	0.600	0.28
231_F	234_W	0.600	0.28
317_K	405_F	0.600	0.28
647_Y	696_G	0.599	0.28
71_I	153_I	0.598	0.28
733_R	783_N	0.598	0.28
178_Y	250_L	0.598	0.28
123_T	706_D	0.597	0.28
15_E	418_E	0.596	0.28
218_F	221_K	0.596	0.28
106_P	611_L	0.595	0.27
191_D	696_G	0.595	0.27
19_M	320_I	0.595	0.27
72_Y	314_G	0.595	0.27
73_I	612_Y	0.594	0.27
321_M	542_G	0.594	0.27
51_A	670_I	0.593	0.27
133_D	185_L	0.593	0.27
326_T	330_S	0.593	0.27
502_A	515_V	0.593	0.27
234_W	237_A	0.593	0.27
556_R	560_E	0.593	0.27
77_K	490_E	0.592	0.27
244_L	581_I	0.592	0.27
373_M	691_I	0.592	0.27
269_L	675_L	0.590	0.27
466_F	546_S	0.590	0.27
425_L	700_K	0.590	0.27
713_A	763_W	0.589	0.27
360_E	506_I	0.588	0.27
210_I	217_N	0.588	0.27
584_I	748_G	0.588	0.27
31_P	321_M	0.588	0.27
210_I	732_R	0.588	0.27
259_T	263_H	0.588	0.27
408_I	422_L	0.588	0.27
108_K	115_K	0.587	0.27
40_V	275_Y	0.587	0.27
10_R	26_E	0.586	0.27
32_I	529_P	0.585	0.27
209_I	415_R	0.585	0.27
28_S	182_R	0.584	0.27
119_H	184_G	0.584	0.27
279_S	338_S	0.582	0.27
250_L	426_V	0.582	0.27
675_L	737_G	0.581	0.27
219_E	300_A	0.580	0.27
615_V	648_G	0.580	0.27
190_S	250_L	0.579	0.26
106_P	739_I	0.579	0.26
387_R	688_L	0.579	0.26
11_K	557_K	0.578	0.26
324_P	398_K	0.578	0.26
40_V	189_V	0.578	0.26
80_I	453_R	0.578	0.26
397_Q	628_L	0.578	0.26
479_F	492_D	0.578	0.26
542_G	696_G	0.578	0.26
120_I	279_S	0.577	0.26
71_I	738_K	0.576	0.26
98_V	146_K	0.576	0.26
146_K	638_L	0.576	0.26
29_F	46_Y	0.576	0.26
131_D	763_W	0.576	0.26
378_I	651_I	0.576	0.26
73_I	496_V	0.574	0.26
270_G	273_E	0.574	0.26
267_E	289_A	0.573	0.26
101_K	692_Q	0.573	0.26
292_E	733_R	0.572	0.26
82_D	379_D	0.571	0.26
236_S	245_I	0.571	0.26
510_G	647_Y	0.571	0.26
314_G	723_T	0.570	0.26
509_S	693_P	0.569	0.26
272_K	700_K	0.569	0.26
129_E	470_F	0.569	0.26
74_T	164_Q	0.568	0.26
215_T	734_V	0.567	0.26
255_S	330_S	0.567	0.26
109_E	228_D	0.566	0.26
102_H	250_L	0.566	0.26
778_G	782_V	0.565	0.26
173_K	408_I	0.564	0.26
216_R	344_G	0.563	0.26
46_Y	505_I	0.563	0.26
416_N	599_D	0.563	0.26
418_E	460_N	0.563	0.26
97_L	586_E	0.563	0.26
57_L	227_N	0.562	0.25
338_S	523_N	0.562	0.25
366_L	415_R	0.562	0.25
401_I	405_F	0.562	0.25
266_L	505_I	0.562	0.25
74_T	317_K	0.562	0.25
129_E	391_G	0.562	0.25
474_N	693_P	0.561	0.25
515_V	686_A	0.561	0.25
94_L	477_E	0.561	0.25
154_H	323_R	0.561	0.25
255_S	546_S	0.561	0.25
675_L	714_L	0.561	0.25
401_I	452_W	0.560	0.25
597_S	740_K	0.560	0.25
299_K	670_I	0.560	0.25
601_I	733_R	0.560	0.25
210_I	213_N	0.560	0.25
259_T	555_I	0.560	0.25
13_I	21_L	0.560	0.25
40_V	485_G	0.560	0.25
547_K	649_F	0.559	0.25
219_E	732_R	0.559	0.25
659_F	743_Y	0.559	0.25
122_V	693_P	0.559	0.25
476_D	690_E	0.559	0.25
330_S	686_A	0.557	0.25
381_G	423_L	0.557	0.25
308_E	619_R	0.557	0.25
519_N	555_I	0.557	0.25
251_V	488_V	0.556	0.25
402_E	668_R	0.556	0.25
394_L	466_F	0.556	0.25
72_Y	90_W	0.555	0.25
360_E	555_I	0.555	0.25
403_E	407_I	0.553	0.25
98_V	678_I	0.553	0.25
349_E	425_L	0.552	0.25
11_K	14_E	0.552	0.25
628_L	651_I	0.552	0.25
279_S	493_A	0.551	0.25
377_F	725_K	0.551	0.25
471_S	688_L	0.551	0.25
38_T	682_P	0.550	0.25
297_N	603_V	0.550	0.25
289_A	301_V	0.550	0.25
217_N	740_K	0.550	0.25
283_R	291_G	0.550	0.25
209_I	586_E	0.549	0.25
338_S	475_N	0.549	0.25
367_S	372_K	0.549	0.25
13_I	387_R	0.549	0.25
92_S	594_K	0.549	0.25
33_S	55_P	0.548	0.25
56_I	120_I	0.548	0.25
23_R	734_V	0.548	0.25
218_F	345_V	0.547	0.25
31_P	34_N	0.547	0.25
683_L	722_F	0.546	0.25
265_E	272_K	0.546	0.25
301_V	766_D	0.546	0.25
37_N	73_I	0.546	0.25
547_K	686_A	0.546	0.25
357_D	727_T	0.545	0.24
156_L	176_I	0.544	0.24
77_K	414_Y	0.544	0.24
14_E	19_M	0.544	0.24
225_L	231_F	0.544	0.24
42_A	628_L	0.543	0.24
87_I	91_A	0.542	0.24
409_R	736_E	0.542	0.24
549_P	730_F	0.542	0.24
402_E	405_F	0.542	0.24
301_V	601_I	0.541	0.24
51_A	212_L	0.541	0.24
67_P	113_R	0.541	0.24
163_T	357_D	0.541	0.24
559_M	621_S	0.540	0.24
357_D	548_S	0.540	0.24
398_K	454_F	0.540	0.24
42_A	484_N	0.540	0.24
150_V	169_L	0.540	0.24
141_H	525_I	0.539	0.24
53_L	91_A	0.539	0.24
485_G	670_I	0.539	0.24
106_P	295_N	0.539	0.24
492_D	618_E	0.539	0.24
415_R	725_K	0.539	0.24
150_V	184_G	0.539	0.24
258_S	675_L	0.539	0.24
616_I	620_I	0.539	0.24
119_H	199_L	0.538	0.24
360_E	485_G	0.538	0.24
54_L	748_G	0.537	0.24
414_Y	639_N	0.537	0.24
389_I	392_M	0.537	0.24
251_V	474_N	0.537	0.24
405_F	532_E	0.536	0.24
481_L	527_V	0.535	0.24
547_K	647_Y	0.535	0.24
143_K	729_E	0.535	0.24
209_I	295_N	0.534	0.24
402_E	406_N	0.534	0.24
144_N	297_N	0.534	0.24
127_G	550_L	0.534	0.24
149_V	198_F	0.534	0.24
247_K	347_K	0.533	0.24
102_H	471_S	0.533	0.24
435_I	443_K	0.532	0.24
391_G	394_L	0.532	0.24
616_I	739_I	0.531	0.24
606_K	705_E	0.531	0.24
122_V	549_P	0.530	0.24
74_T	91_A	0.530	0.24
33_S	58_N	0.530	0.24
492_D	547_K	0.529	0.24
56_I	155_E	0.529	0.24
235_K	469_F	0.529	0.24
92_S	666_N	0.529	0.24
294_R	681_S	0.529	0.24
22_T	267_E	0.528	0.23
731_I	735_R	0.528	0.23
547_K	684_Y	0.528	0.23
384_V	780_Y	0.527	0.23
50_E	53_L	0.526	0.23
210_I	675_L	0.526	0.23
415_R	418_E	0.526	0.23
371_G	600_V	0.525	0.23
15_E	740_K	0.525	0.23
549_P	733_R	0.524	0.23
339_G	344_G	0.524	0.23
563_N	739_I	0.523	0.23
80_I	351_I	0.523	0.23
601_I	614_V	0.523	0.23
74_T	87_I	0.522	0.23
308_E	399_M	0.522	0.23
388_E	407_I	0.522	0.23
163_T	413_I	0.521	0.23
220_I	223_N	0.521	0.23
651_I	774_A	0.521	0.23
406_N	419_L	0.521	0.23
150_V	282_S	0.521	0.23
133_D	279_S	0.520	0.23
330_S	500_V	0.520	0.23
631_L	673_I	0.520	0.23
388_E	459_K	0.519	0.23
241_I	597_S	0.518	0.23
547_K	646_I	0.518	0.23
72_Y	96_F	0.518	0.23
15_E	203_S	0.517	0.23
219_E	365_Y	0.517	0.23
279_S	321_M	0.516	0.23
449_F	711_K	0.516	0.23
408_I	740_K	0.516	0.23
239_E	245_I	0.515	0.23
775_L	778_G	0.515	0.23
199_L	585_F	0.515	0.23
222_I	338_S	0.514	0.23
8_R	62_K	0.514	0.23
318_K	328_V	0.514	0.23
100_R	559_M	0.513	0.23
34_N	706_D	0.513	0.23
266_L	302_V	0.513	0.23
478_T	492_D	0.513	0.23
14_E	603_V	0.513	0.23
560_E	733_R	0.513	0.23
556_R	616_I	0.512	0.23
592_G	688_L	0.512	0.23
145_V	408_I	0.512	0.23
239_E	662_I	0.512	0.23
335_L	683_L	0.511	0.23
110_K	498_K	0.511	0.23
155_E	700_K	0.511	0.23
259_T	628_L	0.511	0.23
343_H	369_K	0.510	0.22
243_Q	751_R	0.510	0.22
338_S	582_I	0.510	0.22
143_K	601_I	0.510	0.22
225_L	351_I	0.509	0.22
537_I	666_N	0.509	0.22
52_A	314_G	0.508	0.22
378_I	515_V	0.508	0.22
641_S	652_K	0.508	0.22
88_D	415_R	0.508	0.22
428_Y	686_A	0.508	0.22
97_L	482_K	0.507	0.22
185_L	555_I	0.507	0.22
588_Y	646_I	0.506	0.22
250_L	658_L	0.506	0.22
178_Y	710_I	0.506	0.22
12_L	102_H	0.506	0.22
37_N	411_T	0.505	0.22
338_S	434_I	0.505	0.22
391_G	475_N	0.505	0.22
408_I	417_L	0.505	0.22
250_L	633_T	0.505	0.22
642_S	705_E	0.505	0.22
193_D	709_L	0.504	0.22
31_P	210_I	0.504	0.22
603_V	612_Y	0.504	0.22
145_V	368_A	0.504	0.22
77_K	83_L	0.503	0.22
119_H	293_L	0.503	0.22
660_K	733_R	0.503	0.22
220_I	496_V	0.502	0.22
456_R	459_K	0.502	0.22
8_R	175_F	0.501	0.22
50_E	387_R	0.501	0.22
153_I	648_G	0.501	0.22
110_K	739_I	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2p6rA	1	0.6527	100	0.799	Contact Map
2va8A	1	0.6645	100	0.8	Contact Map
2zj8A	2	0.6624	100	0.802	Contact Map
4f92B	1	0.7428	100	0.807	Contact Map
5agaA	4	0.701	100	0.819	Contact Map
4bgdA	1	0.926	100	0.82	Contact Map
4w7sA	2	0.4191	100	0.823	Contact Map
4d25A	1	0.3976	100	0.824	Contact Map
4u4cA	1	0.8221	100	0.825	Contact Map
4bujA	1	0.6013	100	0.825	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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