GREMLIN Database
TOP6B - Type 2 DNA topoisomerase 6 subunit B
UniProt: Q97ZF0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 530 (499)
Sequences: 173 (115)
Seq/√Len: 5.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
86_V131_T8.6931.00
37_R41_E5.2800.98
388_I413_V4.4500.94
129_I338_I3.8020.88
35_T72_V3.7790.88
248_L285_V3.5520.84
254_I279_L3.4530.82
384_K389_W3.3250.80
413_V440_I3.2330.78
322_I355_G3.0000.72
115_A174_I2.9940.72
385_S388_I2.9600.71
354_A443_A2.9560.71
119_S219_T2.9030.69
129_I155_I2.7650.65
354_A388_I2.7200.64
126_P153_P2.6790.62
322_I326_L2.6770.62
33_Y37_R2.6600.62
33_Y41_E2.6600.62
266_G381_Y2.6200.61
26_P422_Y2.5550.59
36_V60_I2.4880.56
75_V171_S2.4410.55
474_Y481_S2.4010.54
244_M257_F2.3710.53
30_R193_R2.3530.52
354_A385_S2.3490.52
230_K261_E2.3130.51
129_I395_L2.2970.50
333_D458_K2.2910.50
104_T173_A2.2620.49
195_Y380_I2.2430.48
55_N202_E2.2000.47
60_I225_P2.1980.47
322_I412_M2.1100.44
123_Q380_I2.0980.44
98_K474_Y2.0900.43
196_I321_L2.0820.43
72_V411_V2.0750.43
23_A37_R2.0340.42
23_A41_E2.0340.42
283_K292_E2.0260.41
210_G354_A1.9950.40
144_L392_V1.9780.40
81_I339_T1.9750.40
239_E425_A1.9700.40
33_Y419_K1.9570.39
118_Y414_H1.9510.39
73_N173_A1.9060.38
248_L444_L1.8880.37
35_T168_H1.8710.36
25_F325_G1.8650.36
229_V313_S1.8540.36
79_I200_Y1.8280.35
58_I464_A1.8270.35
392_V395_L1.8200.35
376_K422_Y1.8190.35
95_Y414_H1.7970.34
98_K481_S1.7960.34
13_A35_T1.7950.34
415_L430_I1.7700.33
41_E108_Y1.7630.33
37_R108_Y1.7630.33
236_V426_G1.7480.33
108_Y198_T1.7290.32
475_V501_I1.7140.32
108_Y114_A1.7020.32
108_Y200_Y1.6690.31
118_Y381_Y1.6650.30
340_R439_E1.6540.30
317_I422_Y1.6490.30
153_P315_S1.6440.30
115_A467_K1.6290.29
237_D425_A1.6220.29
37_R239_E1.6210.29
41_E239_E1.6210.29
473_K476_P1.6140.29
139_L426_G1.6100.29
99_Y107_M1.6100.29
345_Y420_I1.6020.29
79_I376_K1.6020.29
355_G476_P1.5990.29
23_A108_Y1.5920.28
9_S30_R1.5820.28
115_A410_V1.5680.28
84_Q457_E1.5630.28
98_K382_D1.5630.28
23_A33_Y1.5610.28
284_K287_N1.5530.27
149_N394_E1.5460.27
86_V142_F1.5440.27
382_D416_C1.5420.27
141_T159_G1.5420.27
138_R160_S1.5420.27
486_L504_G1.5390.27
50_H79_I1.5360.27
28_P226_P1.5230.27
236_V275_E1.5210.27
356_I448_A1.5170.27
9_S123_Q1.5150.26
205_F420_I1.5080.26
99_Y108_Y1.5060.26
257_F296_L1.5050.26
227_Q333_D1.5020.26
381_Y414_H1.4950.26
180_W186_R1.4860.26
399_R405_D1.4810.26
9_S333_D1.4700.25
58_I274_L1.4680.25
113_K200_Y1.4560.25
253_T370_V1.4560.25
326_L371_L1.4540.25
254_I467_K1.4520.25
336_A450_K1.4410.25
93_V99_Y1.4390.25
194_T342_P1.4190.24
39_L112_V1.4140.24
245_I285_V1.4090.24
17_K121_M1.4030.24
104_T107_M1.4020.24
195_Y330_F1.4020.24
204_I236_V1.3930.23
289_T352_V1.3760.23
23_A99_Y1.3730.23
396_D399_R1.3720.23
181_P415_L1.3720.23
123_Q265_I1.3690.23
331_N485_F1.3640.23
91_G396_D1.3630.23
280_R285_V1.3620.23
238_R312_D1.3590.23
19_N43_S1.3580.23
27_N377_I1.3530.23
95_Y118_Y1.3530.23
416_C425_A1.3470.22
13_A153_P1.3450.22
144_L221_K1.3390.22
263_Q376_K1.3350.22
226_P337_S1.3320.22
147_D428_E1.3290.22
123_Q316_V1.3260.22
23_A386_D1.3220.22
235_G358_F1.3020.21
108_Y386_D1.2940.21
94_L230_K1.2910.21
117_L269_T1.2900.21
35_T180_W1.2900.21
49_V100_V1.2800.21
137_K273_I1.2710.21
114_A401_G1.2630.21
186_R424_S1.2620.21
155_I230_K1.2550.20
357_A362_I1.2540.20
147_D426_G1.2530.20
113_K391_V1.2500.20
501_I504_G1.2490.20
27_N178_G1.2430.20
22_L114_A1.2410.20
17_K382_D1.2370.20
404_S407_Y1.2290.20
354_A413_V1.2290.20
124_D316_V1.2280.20
205_F418_T1.2270.20
34_Q47_T1.2230.20
155_I222_I1.2230.20
17_K89_A1.2200.20
155_I302_K1.2120.19
110_L423_K1.2110.19
384_K462_Q1.2080.19
110_L418_T1.2020.19
226_P406_Q1.1950.19
176_I230_K1.1880.19
220_N285_V1.1860.19
107_M386_D1.1800.19
392_V410_V1.1780.19
326_L412_M1.1770.19
50_H376_K1.1740.19
341_K422_Y1.1660.19
37_R114_A1.1660.19
41_E114_A1.1660.19
41_E200_Y1.1600.18
37_R200_Y1.1600.18
132_S467_K1.1600.18
320_D336_A1.1590.18
37_R423_K1.1550.18
41_E423_K1.1550.18
30_R483_A1.1470.18
99_Y114_A1.1350.18
33_Y200_Y1.1340.18
332_P385_S1.1300.18
219_T455_L1.1270.18
32_L129_I1.1200.18
89_A423_K1.1200.18
39_L237_D1.1160.18
71_K444_L1.1150.18
131_T148_I1.1140.18
237_D426_G1.1120.17
264_S307_R1.0970.17
39_L239_E1.0940.17
328_K370_V1.0910.17
235_G350_F1.0910.17
119_S209_E1.0890.17
503_E508_L1.0850.17
283_K430_I1.0820.17
197_I479_S1.0820.17
86_V298_E1.0780.17
17_K197_I1.0770.17
235_G334_F1.0750.17
120_Q235_G1.0710.17
332_P357_A1.0700.17
337_S355_G1.0700.17
219_T321_L1.0660.17
147_D154_I1.0640.17
385_S441_K1.0620.17
95_Y381_Y1.0610.17
119_S398_K1.0600.17
491_K500_E1.0570.16
23_A237_D1.0560.16
277_V381_Y1.0530.16
128_E143_K1.0520.16
354_A430_I1.0490.16
34_Q48_D1.0450.16
13_A152_E1.0440.16
96_S461_E1.0440.16
313_S425_A1.0420.16
266_G269_T1.0410.16
44_L257_F1.0390.16
201_A384_K1.0390.16
164_N273_I1.0360.16
150_K428_E1.0350.16
13_A119_S1.0330.16
202_E216_P1.0300.16
174_I330_F1.0290.16
60_I209_E1.0280.16
39_L426_G1.0260.16
236_V398_K1.0230.16
102_R238_R1.0230.16
177_P415_L1.0190.16
291_E370_V1.0180.16
21_E391_V1.0170.16
261_E455_L1.0150.16
43_S326_L1.0150.16
474_Y501_I1.0140.16
252_Y285_V1.0100.16
99_Y386_D1.0100.16
70_Y302_K1.0080.16
31_A178_G1.0030.16
153_P417_S1.0000.15
94_L100_V1.0000.15
351_I354_A0.9970.15
117_L120_Q0.9970.15
316_V325_G0.9960.15
118_Y266_G0.9960.15
170_T201_A0.9910.15
22_L323_E0.9870.15
343_K355_G0.9860.15
131_T289_T0.9860.15
279_L381_Y0.9770.15
74_V228_E0.9760.15
498_Q502_V0.9750.15
285_V300_F0.9730.15
195_Y415_L0.9690.15
108_Y391_V0.9670.15
133_P286_K0.9650.15
237_D262_F0.9620.15
21_E72_V0.9620.15
8_A438_K0.9610.15
262_F288_L0.9580.15
27_N428_E0.9580.15
131_T248_L0.9560.15
500_E504_G0.9530.15
355_G373_Y0.9530.15
64_D292_E0.9530.15
153_P348_H0.9530.15
23_A423_K0.9510.15
23_A200_Y0.9490.15
79_I108_Y0.9470.15
263_Q266_G0.9410.14
30_R96_S0.9390.14
60_I486_L0.9380.14
150_K155_I0.9330.14
412_M479_S0.9330.14
106_G109_G0.9320.14
88_N242_K0.9310.14
16_F374_A0.9290.14
56_I460_K0.9270.14
74_V152_E0.9250.14
108_Y423_K0.9230.14
355_G498_Q0.9210.14
227_Q341_K0.9200.14
37_R132_S0.9200.14
41_E132_S0.9200.14
340_R449_R0.9200.14
86_V248_L0.9160.14
115_A432_E0.9160.14
307_R354_A0.9140.14
249_K253_T0.9120.14
131_T254_I0.9110.14
358_F449_R0.9100.14
430_I445_M0.9090.14
180_W198_T0.9080.14
178_G428_E0.9020.14
293_I300_F0.8990.14
133_P274_L0.8980.14
33_Y386_D0.8960.14
303_Y445_M0.8890.14
114_A377_I0.8890.14
79_I263_Q0.8840.14
322_I476_P0.8840.14
88_N92_R0.8820.14
377_I391_V0.8810.14
292_E298_E0.8800.14
44_L349_P0.8790.13
239_E423_K0.8780.13
20_P348_H0.8750.13
110_L113_K0.8740.13
249_K503_E0.8740.13
352_V415_L0.8710.13
58_I253_T0.8700.13
329_I344_A0.8700.13
129_I288_L0.8690.13
207_D210_G0.8690.13
180_W208_P0.8680.13
242_K293_I0.8670.13
296_L368_P0.8650.13
104_T113_K0.8650.13
36_V312_D0.8650.13
41_E198_T0.8640.13
37_R198_T0.8640.13
333_D495_P0.8610.13
72_V192_K0.8590.13
362_I390_K0.8580.13
13_A295_R0.8570.13
303_Y469_L0.8560.13
30_R428_E0.8520.13
33_Y113_K0.8520.13
232_H372_R0.8500.13
99_Y391_V0.8490.13
271_D284_K0.8480.13
23_A107_M0.8480.13
129_I272_K0.8430.13
13_A456_S0.8410.13
147_D497_Y0.8370.13
163_N474_Y0.8350.13
191_I213_T0.8340.13
219_T262_F0.8320.13
148_I429_S0.8320.13
91_G115_A0.8320.13
382_D423_K0.8300.13
21_E308_S0.8280.13
380_I473_K0.8280.13
333_D426_G0.8270.13
146_I153_P0.8250.13
23_A49_V0.8240.13
360_G431_A0.8220.13
43_S168_H0.8220.13
87_P315_S0.8220.13
468_L497_Y0.8210.13
173_A210_G0.8170.13
56_I220_N0.8140.13
108_Y113_K0.8130.13
56_I356_I0.8130.13
331_N455_L0.8120.12
114_A407_Y0.8100.12
33_Y108_Y0.8090.12
33_Y110_L0.8050.12
236_V319_E0.8050.12
187_I292_E0.8010.12
318_G421_P0.8010.12
44_L195_Y0.7970.12
31_A300_F0.7970.12
7_F422_Y0.7960.12
336_A373_Y0.7940.12
234_Y444_L0.7900.12
18_R163_N0.7900.12
238_R457_E0.7900.12
37_R237_D0.7890.12
41_E237_D0.7890.12
99_Y110_L0.7890.12
189_E370_V0.7870.12
10_L442_N0.7870.12
92_R178_G0.7860.12
239_E426_G0.7860.12
27_N303_Y0.7840.12
131_T215_Y0.7840.12
13_A261_E0.7810.12
8_A349_P0.7760.12
260_S471_Y0.7750.12
481_S501_I0.7740.12
418_T476_P0.7740.12
235_G449_R0.7730.12
120_Q439_E0.7730.12
196_I301_K0.7710.12
148_I423_K0.7710.12
20_P370_V0.7700.12
282_N287_N0.7680.12
104_T424_S0.7670.12
99_Y237_D0.7670.12
215_Y356_I0.7630.12
355_G463_E0.7600.12
441_K445_M0.7580.12
348_H418_T0.7570.12
54_P77_N0.7550.12
45_D77_N0.7550.12
45_D76_D0.7550.12
42_N77_N0.7550.12
76_D80_G0.7550.12
38_E76_D0.7550.12
77_N80_G0.7550.12
42_N76_D0.7550.12
38_E77_N0.7550.12
54_P76_D0.7550.12
30_R390_K0.7520.12
17_K36_V0.7520.12
371_L390_K0.7520.12
438_K467_K0.7520.12
38_E42_N0.7510.12
38_E54_P0.7510.12
42_N45_D0.7510.12
42_N54_P0.7510.12
38_E45_D0.7510.12
45_D80_G0.7510.12
42_N80_G0.7510.12
54_P80_G0.7510.12
38_E80_G0.7510.12
45_D54_P0.7510.12
445_M448_A0.7510.12
502_V508_L0.7510.12
468_L471_Y0.7510.12
326_L390_K0.7500.12
96_S373_Y0.7490.12
359_G421_P0.7470.12
56_I434_E0.7460.12
265_I390_K0.7460.12
197_I418_T0.7450.12
22_L389_W0.7440.12
336_A376_K0.7440.12
6_K288_L0.7430.12
107_M239_E0.7430.12
469_L500_E0.7410.12
8_A65_E0.7390.11
108_Y377_I0.7340.11
19_N48_D0.7320.11
196_I302_K0.7310.11
30_R405_D0.7300.11
238_R344_A0.7300.11
256_E392_V0.7300.11
128_E215_Y0.7290.11
61_D287_N0.7280.11
273_I319_E0.7270.11
125_K129_I0.7250.11
41_E99_Y0.7240.11
37_R99_Y0.7240.11
23_A114_A0.7210.11
23_A198_T0.7150.11
95_Y416_C0.7140.11
117_L358_F0.7140.11
22_L409_M0.7120.11
220_N438_K0.7100.11
228_E350_F0.7090.11
355_G458_K0.7080.11
50_H81_I0.7080.11
21_E237_D0.7050.11
189_E358_F0.7050.11
85_E88_N0.7050.11
168_H262_F0.7040.11
255_K292_E0.7030.11
95_Y424_S0.7020.11
90_F439_E0.7000.11
58_I220_N0.6980.11
93_V382_D0.6970.11
99_Y113_K0.6960.11
33_Y428_E0.6950.11
171_S412_M0.6940.11
439_E449_R0.6930.11
21_E376_K0.6930.11
22_L27_N0.6930.11
210_G265_I0.6930.11
113_K242_K0.6930.11
91_G192_K0.6920.11
155_I295_R0.6910.11
155_I345_Y0.6910.11
352_V430_I0.6900.11
288_L293_I0.6890.11
488_S492_E0.6890.11
97_S454_Y0.6880.11
367_E470_A0.6870.11
107_M112_V0.6860.11
92_R152_E0.6860.11
267_D291_E0.6850.11
91_G261_E0.6850.11
200_Y423_K0.6840.11
270_A414_H0.6840.11
32_L473_K0.6820.11
103_Q359_G0.6820.11
51_G150_K0.6800.11
81_I241_I0.6790.11
311_A388_I0.6760.11
231_P439_E0.6760.11
112_V407_Y0.6760.11
203_F412_M0.6730.11
113_K377_I0.6710.11
25_F422_Y0.6690.11
298_E438_K0.6690.11
99_Y425_A0.6690.11
92_R398_K0.6680.11
314_L418_T0.6680.11
63_I465_K0.6670.11
89_A263_Q0.6670.11
203_F452_K0.6660.11
97_S321_L0.6640.11
373_Y376_K0.6630.11
64_D288_L0.6630.11
23_A113_K0.6630.11
41_E186_R0.6630.11
37_R186_R0.6630.11
124_D230_K0.6620.10
306_F377_I0.6580.10
176_I409_M0.6580.10
40_I395_L0.6580.10
315_S348_H0.6580.10
83_P300_F0.6580.10
419_K474_Y0.6550.10
149_N294_T0.6530.10
174_I443_A0.6510.10
112_V239_E0.6510.10
178_G299_T0.6510.10
203_F454_Y0.6510.10
103_Q309_P0.6500.10
139_L163_N0.6500.10
41_E414_H0.6490.10
37_R414_H0.6490.10
246_N486_L0.6490.10
129_I281_P0.6480.10
474_Y504_G0.6480.10
56_I216_P0.6480.10
69_I293_I0.6480.10
262_F381_Y0.6470.10
15_F96_S0.6470.10
350_F359_G0.6470.10
17_K423_K0.6450.10
218_L336_A0.6440.10
33_Y93_V0.6440.10
33_Y423_K0.6440.10
23_A93_V0.6430.10
237_D277_V0.6420.10
322_I500_E0.6420.10
255_K271_D0.6410.10
30_R322_I0.6390.10
152_E288_L0.6390.10
39_L404_S0.6390.10
93_V110_L0.6370.10
37_R93_V0.6350.10
41_E93_V0.6350.10
103_Q111_G0.6340.10
414_H449_R0.6320.10
235_G431_A0.6310.10
43_S266_G0.6310.10
382_D425_A0.6310.10
8_A251_D0.6310.10
87_P90_F0.6300.10
20_P170_T0.6300.10
97_S118_Y0.6280.10
37_R377_I0.6270.10
41_E377_I0.6270.10
337_S460_K0.6250.10
301_K462_Q0.6240.10
41_E416_C0.6240.10
37_R416_C0.6240.10
128_E230_K0.6230.10
119_S328_K0.6230.10
396_D471_Y0.6230.10
30_R58_I0.6220.10
87_P421_P0.6210.10
237_D423_K0.6210.10
167_F387_V0.6190.10
420_I464_A0.6180.10
389_W413_V0.6180.10
144_L447_V0.6170.10
197_I393_E0.6160.10
98_K501_I0.6160.10
309_P379_L0.6150.10
341_K450_K0.6130.10
120_Q194_T0.6110.10
192_K418_T0.6100.10
116_V414_H0.6090.10
116_V119_S0.6080.10
122_H485_F0.6080.10
31_A208_P0.6080.10
130_E322_I0.6050.10
236_V345_Y0.6050.10
358_F421_P0.6040.10
478_V482_L0.6040.10
252_Y256_E0.6030.10
146_I295_R0.6020.10
167_F401_G0.6020.10
95_Y117_L0.6020.10
26_P466_K0.6010.10
46_A74_V0.6000.10
407_Y422_Y0.5990.10
128_E173_A0.5980.10
10_L94_L0.5980.10
147_D454_Y0.5980.10
114_A414_H0.5980.10
111_G379_L0.5970.10
89_A129_I0.5930.10
345_Y350_F0.5920.10
57_K430_I0.5920.10
102_R143_K0.5920.10
481_S491_K0.5910.10
288_L433_V0.5900.10
13_A482_L0.5900.10
117_L179_D0.5900.10
15_F103_Q0.5900.10
188_Y205_F0.5880.10
86_V229_V0.5880.10
324_L441_K0.5870.10
108_Y112_V0.5870.10
419_K433_V0.5860.10
235_G340_R0.5850.10
341_K489_G0.5840.10
305_D308_S0.5840.10
89_A377_I0.5830.10
26_P325_G0.5830.10
503_E506_F0.5820.10
58_I71_K0.5800.10
7_F383_E0.5800.10
12_P451_L0.5800.10
153_P270_A0.5790.10
144_L220_N0.5780.09
108_Y401_G0.5770.09
12_P460_K0.5770.09
87_P352_V0.5750.09
28_P128_E0.5750.09
409_M474_Y0.5740.09
30_R261_E0.5740.09
381_Y416_C0.5730.09
94_L403_E0.5730.09
30_R303_Y0.5730.09
252_Y460_K0.5720.09
468_L498_Q0.5720.09
131_T142_F0.5720.09
183_A468_L0.5700.09
241_I297_V0.5700.09
374_A397_W0.5700.09
231_P429_S0.5700.09
113_K180_W0.5680.09
183_A502_V0.5680.09
103_Q190_Y0.5670.09
402_I467_K0.5670.09
44_L105_R0.5660.09
89_A424_S0.5640.09
96_S376_K0.5640.09
342_P382_D0.5630.09
217_R372_R0.5630.09
217_R232_H0.5630.09
173_A203_F0.5610.09
118_Y416_C0.5580.09
172_V264_S0.5580.09
292_E341_K0.5570.09
323_E420_I0.5570.09
58_I189_E0.5570.09
57_K204_I0.5570.09
244_M343_K0.5560.09
266_G434_E0.5560.09
252_Y327_K0.5560.09
291_E365_G0.5550.09
408_Q439_E0.5550.09
116_V300_F0.5500.09
98_K500_E0.5500.09
41_E428_E0.5500.09
37_R428_E0.5500.09
30_R253_T0.5490.09
143_K157_E0.5490.09
343_K422_Y0.5480.09
113_K386_D0.5450.09
104_T299_T0.5450.09
234_Y430_I0.5450.09
73_N123_Q0.5440.09
286_K338_I0.5430.09
320_D339_T0.5420.09
12_P423_K0.5420.09
155_I298_E0.5410.09
71_K131_T0.5400.09
296_L381_Y0.5370.09
248_L251_D0.5370.09
147_D506_F0.5370.09
354_A497_Y0.5370.09
492_E502_V0.5360.09
130_E361_S0.5360.09
345_Y436_I0.5360.09
163_N481_S0.5350.09
27_N236_V0.5350.09
255_K485_F0.5340.09
129_I290_E0.5330.09
155_I455_L0.5330.09
41_E386_D0.5330.09
37_R386_D0.5330.09
51_G297_V0.5320.09
196_I418_T0.5320.09
20_P65_E0.5320.09
41_E426_G0.5320.09
37_R426_G0.5320.09
275_E302_K0.5280.09
402_I407_Y0.5270.09
36_V355_G0.5260.09
144_L211_N0.5250.09
89_A239_E0.5250.09
416_C423_K0.5240.09
360_G436_I0.5240.09
47_T110_L0.5240.09
11_S115_A0.5240.09
15_F358_F0.5220.09
282_N418_T0.5210.09
72_V295_R0.5210.09
289_T292_E0.5200.09
53_L217_R0.5180.09
79_I387_V0.5180.09
28_P485_F0.5180.09
275_E490_N0.5170.09
145_K324_L0.5170.09
321_L414_H0.5160.09
191_I331_N0.5150.09
95_Y266_G0.5130.09
293_I441_K0.5110.09
99_Y180_W0.5110.09
9_S434_E0.5110.09
168_H457_E0.5100.09
132_S237_D0.5100.09
377_I429_S0.5090.09
364_V475_V0.5090.09
62_L412_M0.5070.09
254_I326_L0.5070.09
263_Q389_W0.5060.09
289_T455_L0.5060.09
22_L384_K0.5040.09
35_T267_D0.5040.09
171_S299_T0.5040.09
486_L497_Y0.5040.09
163_N166_G0.5040.09
99_Y239_E0.5030.09
82_P426_G0.5030.09
196_I308_S0.5030.09
37_R270_A0.5030.09
41_E270_A0.5030.09
28_P452_K0.5020.09
275_E282_N0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2q2eB 2 0.9604 100 0.38 Contact Map
2zbkB 1 0.9547 100 0.387 Contact Map
1mu5A 1 0.8679 100 0.416 Contact Map
3lnuA 1 0.5509 100 0.865 Contact Map
1kijA 2 0.6377 100 0.866 Contact Map
4urlA 1 0.6 100 0.866 Contact Map
4wubA 2 0.6434 100 0.867 Contact Map
4i3hA 2 0.7057 100 0.871 Contact Map
3cwvA 1 0.5679 100 0.872 Contact Map
1s16A 2 0.6113 100 0.876 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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