Q97ZD7 - SULSO - GREMLIN Contacts

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Q97ZD7 - Pyruvate kinase

UniProt:	Q97ZD7	Sequences: MRKTKIVATLGPSSEEKVKELAEYVDVFRINFAHGDETSHRKYFDLIRTYAPESSIIVDLPGPKLRLGELKEPIEVKKGDKIVFSQKDGIPVDDELFYSAVKENSDILIADGTIRVRVKSKAKDRVEGTVIEGGILLSRKGINIPNVNLKSGITDNDLKLLKRALDLGADYIGLSFVISENDVKKVKEFVGDEAWVIAKIEKSEALKNLTNIVNESDGIMVARGDLGVETGLENLPLIQRRIVRTSRVFGKPVILATQVLTSMINSPIPTRAEIIDISNSIMQGVDSIMLSDETAIGNYPVESVRTLHNIISNVEKSVKHRPIGPLNSESDAIALAAVNASKVSKADVIVVYSRSGNSILRVSRLRPERNIIGVSPDPRLAKKFKLCYGVIPISINKKMQSIDEIIDVSAKLMQEKIKDLKFKKIVIVGGDPKQEAGKTNFVIVKTLEQQKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	452 (445)
Sequences:	4105 (2314)
Seq/√Len:	109.7

ECOLI - KPYK1 KPYK2
BACSU - KPYK
HALSA - Q9HSA5
SULSO - Q97ZD7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
19_K	53_E	4.436	1.00
198_A	216_S	4.429	1.00
119_K	129_T	4.419	1.00
210_T	245_T	4.120	1.00
41_R	45_D	3.456	1.00
209_L	242_I	3.437	1.00
184_K	215_E	3.244	1.00
117_R	129_T	3.211	1.00
8_A	25_V	3.191	1.00
58_V	164_A	3.074	1.00
206_L	238_I	2.953	1.00
255_L	285_V	2.932	1.00
234_N	313_N	2.871	1.00
25_V	28_F	2.862	1.00
183_V	198_A	2.846	1.00
187_K	196_V	2.811	1.00
55_S	385_K	2.774	1.00
117_R	131_I	2.731	1.00
120_S	127_E	2.618	1.00
17_K	20_E	2.584	1.00
41_R	167_L	2.536	1.00
81_K	127_E	2.494	1.00
77_K	80_D	2.467	1.00
69_E	139_R	2.438	1.00
39_S	43_Y	2.402	1.00
81_K	119_K	2.384	1.00
183_V	196_V	2.347	1.00
82_I	90_I	2.328	1.00
233_E	309_N	2.310	1.00
214_N	249_F	2.308	1.00
15_E	43_Y	2.276	1.00
161_L	172_I	2.242	1.00
23_E	54_S	2.222	1.00
375_S	381_A	2.213	1.00
265_N	298_N	2.200	1.00
181_N	185_K	2.199	1.00
347_D	423_K	2.142	1.00
44_F	167_L	2.119	1.00
230_T	238_I	2.116	1.00
240_R	283_Q	2.088	1.00
197_I	218_G	2.052	1.00
96_L	99_S	2.022	1.00
109_I	136_L	2.010	1.00
308_H	312_S	1.983	1.00
288_I	311_I	1.969	1.00
17_K	301_V	1.940	1.00
168_G	379_R	1.935	1.00
165_L	194_A	1.914	1.00
81_K	129_T	1.891	1.00
76_V	130_V	1.871	1.00
195_W	383_K	1.869	1.00
48_R	51_A	1.869	1.00
103_E	121_K	1.858	1.00
44_F	56_I	1.829	1.00
209_L	213_V	1.815	1.00
73_P	135_I	1.814	1.00
243_V	255_L	1.788	1.00
106_D	115_R	1.782	1.00
158_L	162_K	1.778	1.00
30_I	44_F	1.778	1.00
350_V	425_I	1.776	1.00
116_V	128_G	1.772	1.00
100_A	150_K	1.757	1.00
82_I	128_G	1.756	1.00
84_F	116_V	1.746	1.00
19_K	23_E	1.746	1.00
340_A	442_V	1.730	1.00
75_E	135_I	1.728	1.00
156_N	160_L	1.727	1.00
60_L	64_K	1.722	1.00
83_V	127_E	1.720	1.00
411_K	415_E	1.716	1.00
181_N	184_K	1.707	1.00
219_I	242_I	1.705	1.00
155_D	159_K	1.698	1.00
381_A	394_S	1.696	1.00
174_L	186_V	1.679	1.00
148_N	204_E	1.678	1.00
7_V	254_I	1.669	1.00
80_D	130_V	1.667	1.00
10_L	18_V	1.667	1.00
203_S	207_K	1.654	1.00
180_E	211_N	1.639	1.00
22_A	50_Y	1.627	1.00
188_E	192_D	1.621	1.00
38_T	41_R	1.613	1.00
83_V	125_R	1.606	1.00
27_V	57_I	1.604	1.00
241_R	245_T	1.593	1.00
302_E	305_R	1.592	1.00
20_E	23_E	1.572	1.00
28_F	47_I	1.562	1.00
70_L	138_S	1.558	1.00
7_V	27_V	1.542	1.00
122_A	125_R	1.540	1.00
50_Y	54_S	1.538	1.00
158_L	185_K	1.537	1.00
106_D	117_R	1.522	1.00
197_I	254_I	1.517	1.00
19_K	54_S	1.505	1.00
58_V	169_A	1.489	1.00
2_R	308_H	1.486	1.00
384_F	387_C	1.476	1.00
159_K	162_K	1.475	1.00
299_Y	302_E	1.474	1.00
49_T	53_E	1.466	1.00
412_L	415_E	1.460	1.00
98_Y	126_V	1.457	1.00
87_K	124_D	1.456	1.00
264_I	292_D	1.455	1.00
102_K	105_S	1.453	1.00
35_G	40_H	1.430	1.00
17_K	21_L	1.418	1.00
56_I	169_A	1.418	1.00
346_A	426_V	1.409	1.00
42_K	45_D	1.403	1.00
41_R	166_D	1.383	1.00
235_L	275_I	1.375	1.00
121_K	126_V	1.366	1.00
105_S	147_V	1.365	1.00
37_E	163_R	1.364	1.00
36_D	39_S	1.360	1.00
164_A	169_A	1.360	1.00
110_A	113_T	1.346	1.00
305_R	309_N	1.345	1.00
232_L	306_T	1.344	1.00
42_K	46_L	1.338	1.00
67_L	114_I	1.338	1.00
30_I	47_I	1.333	1.00
158_L	189_F	1.328	1.00
412_L	416_K	1.326	1.00
245_T	249_F	1.324	0.99
208_N	211_N	1.322	0.99
353_S	373_G	1.319	0.99
8_A	28_F	1.317	0.99
281_I	311_I	1.313	0.99
122_A	127_E	1.303	0.99
87_K	125_R	1.295	0.99
193_E	379_R	1.295	0.99
10_L	43_Y	1.293	0.99
202_K	205_A	1.284	0.99
261_T	265_N	1.282	0.99
85_S	125_R	1.279	0.99
14_S	17_K	1.270	0.99
165_L	190_V	1.266	0.99
414_Q	421_K	1.259	0.99
16_E	19_K	1.257	0.99
180_E	215_E	1.255	0.99
101_V	126_V	1.255	0.99
373_G	384_F	1.253	0.99
109_I	116_V	1.251	0.99
67_L	90_I	1.245	0.99
20_E	305_R	1.233	0.99
21_L	304_V	1.230	0.99
68_G	91_P	1.229	0.99
213_V	245_T	1.229	0.99
313_N	316_K	1.224	0.99
19_K	50_Y	1.217	0.99
78_K	133_G	1.217	0.99
46_L	49_T	1.215	0.99
40_H	43_Y	1.207	0.99
238_I	242_I	1.203	0.99
30_I	169_A	1.203	0.99
45_D	49_T	1.192	0.99
86_Q	98_Y	1.192	0.99
184_K	188_E	1.187	0.99
88_D	95_E	1.186	0.99
46_L	50_Y	1.179	0.99
77_K	133_G	1.179	0.99
4_T	311_I	1.179	0.99
329_E	424_K	1.176	0.99
86_Q	89_G	1.175	0.99
243_V	285_V	1.171	0.99
180_E	184_K	1.170	0.99
162_K	166_D	1.164	0.99
332_A	340_A	1.163	0.99
15_E	46_L	1.150	0.99
373_G	390_V	1.139	0.98
73_P	137_L	1.130	0.98
401_S	404_E	1.128	0.98
37_E	160_L	1.126	0.98
52_P	378_P	1.124	0.98
95_E	98_Y	1.124	0.98
144_I	147_V	1.123	0.98
10_L	14_S	1.121	0.98
74_I	136_L	1.110	0.98
61_P	64_K	1.108	0.98
44_F	163_R	1.108	0.98
424_K	446_T	1.106	0.98
15_E	42_K	1.106	0.98
115_R	131_I	1.102	0.98
96_L	100_A	1.099	0.98
30_I	56_I	1.091	0.98
340_A	444_V	1.088	0.98
360_L	387_C	1.085	0.98
429_G	441_F	1.081	0.98
348_V	372_I	1.078	0.98
261_T	264_I	1.077	0.98
237_L	282_M	1.072	0.98
32_F	58_V	1.070	0.98
130_V	133_G	1.069	0.98
84_F	92_V	1.067	0.98
14_S	21_L	1.063	0.98
259_V	277_I	1.057	0.98
331_D	364_R	1.057	0.98
277_I	310_I	1.057	0.98
267_P	299_Y	1.047	0.97
261_T	292_D	1.044	0.97
116_V	130_V	1.038	0.97
180_E	208_N	1.037	0.97
162_K	192_D	1.034	0.97
4_T	281_I	1.024	0.97
185_K	188_E	1.023	0.97
81_K	120_S	1.019	0.97
69_E	138_S	1.017	0.97
170_D	382_K	1.016	0.97
335_L	339_N	1.014	0.97
10_L	47_I	1.010	0.97
47_I	56_I	1.008	0.97
98_Y	121_K	1.006	0.97
274_I	310_I	1.006	0.97
351_V	362_V	1.005	0.97
187_K	217_D	1.002	0.97
70_L	82_I	1.001	0.97
190_V	194_A	1.000	0.97
178_I	204_E	0.999	0.97
119_K	127_E	0.998	0.96
419_D	447_L	0.993	0.96
67_L	137_L	0.988	0.96
20_E	301_V	0.984	0.96
110_A	137_L	0.982	0.96
161_L	186_V	0.979	0.96
144_I	149_L	0.979	0.96
7_V	287_S	0.978	0.96
27_V	287_S	0.977	0.96
216_S	219_I	0.973	0.96
39_S	42_K	0.972	0.96
109_I	128_G	0.970	0.96
232_L	274_I	0.970	0.96
44_F	169_A	0.969	0.96
64_K	202_K	0.967	0.96
45_D	167_L	0.963	0.96
209_L	245_T	0.963	0.96
372_I	413_M	0.958	0.96
374_V	395_I	0.957	0.96
153_I	158_L	0.952	0.95
363_S	387_C	0.952	0.95
78_K	298_N	0.948	0.95
41_R	163_R	0.948	0.95
85_S	89_G	0.946	0.95
61_P	156_N	0.940	0.95
429_G	432_P	0.940	0.95
90_I	136_L	0.939	0.95
57_I	173_G	0.937	0.95
179_S	182_D	0.935	0.95
115_R	268_I	0.935	0.95
169_A	194_A	0.935	0.95
206_L	226_L	0.935	0.95
50_Y	53_E	0.933	0.95
347_D	420_L	0.928	0.95
210_T	213_V	0.928	0.95
92_V	142_I	0.926	0.95
75_E	133_G	0.924	0.95
18_V	50_Y	0.922	0.95
155_D	158_L	0.921	0.95
61_P	160_L	0.919	0.94
84_F	128_G	0.916	0.94
79_G	129_T	0.915	0.94
94_D	100_A	0.915	0.94
97_F	126_V	0.915	0.94
171_Y	197_I	0.914	0.94
70_L	136_L	0.909	0.94
158_L	188_E	0.908	0.94
299_Y	303_S	0.907	0.94
301_V	305_R	0.901	0.94
106_D	131_I	0.897	0.94
213_V	249_F	0.897	0.94
260_L	303_S	0.896	0.94
203_S	234_N	0.892	0.94
84_F	107_I	0.890	0.93
210_T	249_F	0.890	0.93
333_I	428_V	0.882	0.93
38_T	42_K	0.881	0.93
213_V	246_S	0.878	0.93
58_V	64_K	0.872	0.93
14_S	294_T	0.872	0.93
110_A	261_T	0.871	0.93
70_L	137_L	0.867	0.93
143_N	229_E	0.861	0.92
162_K	165_L	0.860	0.92
244_R	248_V	0.858	0.92
165_L	172_I	0.857	0.92
406_I	427_I	0.841	0.91
277_I	288_I	0.837	0.91
282_M	317_S	0.837	0.91
37_E	41_R	0.836	0.91
161_L	189_F	0.833	0.91
334_A	362_V	0.831	0.91
22_A	54_S	0.830	0.91
183_V	216_S	0.830	0.91
22_A	51_A	0.827	0.91
119_K	128_G	0.825	0.91
209_L	241_R	0.824	0.91
101_V	107_I	0.823	0.90
10_L	30_I	0.821	0.90
110_A	292_D	0.814	0.90
211_N	214_N	0.814	0.90
237_L	314_V	0.813	0.90
64_K	141_G	0.812	0.90
243_V	253_V	0.812	0.90
96_L	150_K	0.809	0.90
375_S	394_S	0.809	0.90
55_S	171_Y	0.809	0.90
432_P	440_N	0.806	0.90
360_L	383_K	0.806	0.90
105_S	118_V	0.806	0.90
67_L	142_I	0.801	0.89
103_E	119_K	0.799	0.89
341_S	349_I	0.797	0.89
339_N	343_V	0.796	0.89
74_I	90_I	0.794	0.89
410_A	425_I	0.793	0.89
335_L	343_V	0.792	0.89
102_K	121_K	0.792	0.89
359_I	373_G	0.790	0.89
33_A	160_L	0.787	0.88
18_V	47_I	0.786	0.88
104_N	117_R	0.785	0.88
111_D	258_Q	0.784	0.88
380_L	384_F	0.783	0.88
259_V	307_L	0.781	0.88
379_R	383_K	0.779	0.88
84_F	90_I	0.778	0.88
163_R	167_L	0.776	0.88
197_I	386_L	0.776	0.88
209_L	246_S	0.776	0.88
18_V	46_L	0.773	0.87
70_L	90_I	0.772	0.87
17_K	46_L	0.772	0.87
49_T	52_P	0.771	0.87
333_I	442_V	0.771	0.87
78_K	129_T	0.768	0.87
60_L	202_K	0.766	0.87
378_P	394_S	0.763	0.87
51_A	54_S	0.762	0.87
103_E	120_S	0.762	0.87
27_V	55_S	0.761	0.87
413_M	419_D	0.758	0.86
378_P	382_K	0.758	0.86
64_K	205_A	0.757	0.86
351_V	358_S	0.756	0.86
162_K	189_F	0.754	0.86
111_D	141_G	0.753	0.86
19_K	49_T	0.752	0.86
330_S	357_N	0.752	0.86
110_A	141_G	0.751	0.86
164_A	172_I	0.750	0.86
114_I	130_V	0.749	0.86
348_V	419_D	0.748	0.86
213_V	242_I	0.748	0.86
357_N	361_R	0.746	0.86
218_G	252_P	0.744	0.85
259_V	288_I	0.742	0.85
346_A	444_V	0.741	0.85
55_S	382_K	0.736	0.85
331_D	361_R	0.735	0.85
410_A	445_K	0.734	0.85
145_P	229_E	0.732	0.85
47_I	51_A	0.732	0.85
22_A	47_I	0.730	0.84
227_G	268_I	0.730	0.84
186_V	196_V	0.727	0.84
406_I	443_I	0.725	0.84
146_N	203_S	0.724	0.84
353_S	359_I	0.724	0.84
337_A	341_S	0.722	0.84
247_R	286_D	0.721	0.84
337_A	428_V	0.721	0.84
313_N	317_S	0.719	0.83
200_I	206_L	0.718	0.83
92_V	96_L	0.718	0.83
10_L	46_L	0.717	0.83
76_V	114_I	0.714	0.83
344_S	424_K	0.714	0.83
200_I	209_L	0.712	0.83
67_L	70_L	0.711	0.83
351_V	359_I	0.711	0.83
32_F	160_L	0.709	0.83
279_N	283_Q	0.709	0.83
374_V	413_M	0.707	0.82
14_S	301_V	0.705	0.82
10_L	28_F	0.704	0.82
171_Y	387_C	0.704	0.82
427_I	445_K	0.702	0.82
98_Y	124_D	0.702	0.82
337_A	426_V	0.701	0.82
37_E	159_K	0.701	0.82
296_I	303_S	0.700	0.82
44_F	47_I	0.700	0.82
231_G	235_L	0.700	0.82
189_F	192_D	0.699	0.82
70_L	114_I	0.697	0.82
15_E	18_V	0.695	0.81
60_L	174_L	0.691	0.81
7_V	25_V	0.690	0.81
308_H	311_I	0.688	0.81
238_I	241_R	0.687	0.81
385_K	392_P	0.687	0.81
113_T	266_S	0.686	0.80
83_V	122_A	0.686	0.80
6_I	304_V	0.685	0.80
2_R	26_D	0.683	0.80
32_F	40_H	0.682	0.80
354_R	377_D	0.682	0.80
137_L	296_I	0.680	0.80
152_G	177_V	0.680	0.80
377_D	380_L	0.680	0.80
68_G	93_D	0.679	0.80
235_L	274_I	0.676	0.80
220_M	291_S	0.674	0.79
354_R	397_K	0.674	0.79
114_I	134_G	0.674	0.79
205_A	213_V	0.673	0.79
188_E	191_G	0.673	0.79
282_M	318_V	0.672	0.79
350_V	419_D	0.672	0.79
36_D	139_R	0.671	0.79
10_L	15_E	0.671	0.79
237_L	317_S	0.668	0.79
94_D	97_F	0.668	0.79
114_I	136_L	0.667	0.79
210_T	241_R	0.666	0.79
371_I	390_V	0.662	0.78
30_I	40_H	0.661	0.78
80_D	116_V	0.660	0.78
337_A	349_I	0.660	0.78
252_P	386_L	0.659	0.78
172_I	190_V	0.659	0.78
354_R	376_P	0.657	0.78
82_I	91_P	0.656	0.77
381_A	392_P	0.656	0.77
15_E	39_S	0.655	0.77
6_I	307_L	0.655	0.77
73_P	138_S	0.654	0.77
61_P	292_D	0.653	0.77
34_H	225_D	0.650	0.77
240_R	279_N	0.650	0.77
35_G	39_S	0.650	0.77
282_M	314_V	0.649	0.77
250_G	367_P	0.648	0.77
214_N	251_K	0.646	0.76
171_Y	386_L	0.644	0.76
414_Q	419_D	0.643	0.76
82_I	137_L	0.643	0.76
294_T	303_S	0.640	0.76
338_V	367_P	0.640	0.76
411_K	414_Q	0.637	0.75
340_A	344_S	0.636	0.75
366_R	388_Y	0.635	0.75
136_L	139_R	0.635	0.75
180_E	200_I	0.634	0.75
164_A	168_G	0.634	0.75
114_I	133_G	0.632	0.75
426_V	444_V	0.631	0.75
187_K	191_G	0.631	0.75
281_I	288_I	0.628	0.74
18_V	21_L	0.626	0.74
40_H	164_A	0.626	0.74
209_L	219_I	0.626	0.74
76_V	80_D	0.625	0.74
10_L	25_V	0.625	0.74
31_N	34_H	0.624	0.74
330_S	361_R	0.624	0.74
410_A	447_L	0.624	0.74
181_N	211_N	0.624	0.74
27_V	385_K	0.623	0.74
260_L	306_T	0.623	0.74
434_Q	437_G	0.621	0.74
2_R	275_I	0.620	0.73
259_V	291_S	0.619	0.73
99_S	150_K	0.619	0.73
101_V	118_V	0.619	0.73
250_G	364_R	0.618	0.73
245_T	248_V	0.617	0.73
21_L	28_F	0.617	0.73
420_L	423_K	0.617	0.73
358_S	430_G	0.616	0.73
200_I	242_I	0.616	0.73
43_Y	46_L	0.615	0.73
21_L	301_V	0.612	0.72
153_I	161_L	0.612	0.72
83_V	124_D	0.612	0.72
186_V	189_F	0.612	0.72
431_D	443_I	0.611	0.72
100_A	178_I	0.610	0.72
428_V	439_T	0.610	0.72
84_F	97_F	0.609	0.72
328_S	331_D	0.609	0.72
399_M	408_V	0.608	0.72
241_R	317_S	0.606	0.72
195_W	360_L	0.606	0.72
399_M	405_I	0.606	0.72
179_S	208_N	0.606	0.72
84_F	109_I	0.606	0.72
85_S	98_Y	0.605	0.72
70_L	73_P	0.604	0.71
306_T	310_I	0.603	0.71
348_V	370_N	0.603	0.71
65_L	142_I	0.602	0.71
237_L	313_N	0.601	0.71
61_P	202_K	0.601	0.71
179_S	211_N	0.600	0.71
359_I	392_P	0.600	0.71
437_G	440_N	0.600	0.71
44_F	48_R	0.598	0.71
252_P	286_D	0.597	0.71
135_I	265_N	0.595	0.70
176_F	225_D	0.595	0.70
78_K	299_Y	0.594	0.70
236_P	388_Y	0.594	0.70
58_V	163_R	0.593	0.70
99_S	124_D	0.593	0.70
168_G	194_A	0.592	0.70
329_E	351_V	0.591	0.70
306_T	309_N	0.591	0.70
410_A	419_D	0.590	0.70
82_I	130_V	0.590	0.70
281_I	314_V	0.589	0.70
153_I	189_F	0.587	0.69
65_L	156_N	0.587	0.69
185_K	189_F	0.587	0.69
23_E	53_E	0.586	0.69
399_M	404_E	0.586	0.69
341_S	346_A	0.585	0.69
318_V	323_I	0.585	0.69
190_V	195_W	0.584	0.69
294_T	307_L	0.579	0.68
220_M	289_M	0.579	0.68
21_L	25_V	0.577	0.68
110_A	140_K	0.577	0.68
94_D	178_I	0.576	0.68
67_L	84_F	0.576	0.68
344_S	444_V	0.576	0.68
217_D	251_K	0.575	0.68
391_I	418_K	0.574	0.68
171_Y	195_W	0.573	0.67
72_E	138_S	0.572	0.67
76_V	82_I	0.572	0.67
426_V	442_V	0.572	0.67
177_V	198_A	0.571	0.67
152_G	178_I	0.571	0.67
2_R	6_I	0.571	0.67
60_L	141_G	0.571	0.67
337_A	346_A	0.570	0.67
342_K	368_E	0.570	0.67
176_F	229_E	0.569	0.67
33_A	58_V	0.569	0.67
247_R	255_L	0.569	0.67
434_Q	439_T	0.567	0.67
254_I	289_M	0.567	0.67
344_S	426_V	0.567	0.67
352_Y	405_I	0.567	0.67
232_L	275_I	0.566	0.67
430_G	439_T	0.566	0.67
67_L	140_K	0.562	0.66
367_P	371_I	0.562	0.66
372_I	418_K	0.562	0.66
76_V	109_I	0.561	0.66
198_A	219_I	0.559	0.66
153_I	186_V	0.559	0.66
61_P	205_A	0.558	0.65
16_E	46_L	0.558	0.65
302_E	306_T	0.556	0.65
98_Y	123_K	0.555	0.65
51_A	382_K	0.555	0.65
6_I	308_H	0.554	0.65
408_V	411_K	0.554	0.65
374_V	393_I	0.551	0.64
200_I	218_G	0.551	0.64
373_G	392_P	0.551	0.64
99_S	121_K	0.551	0.64
57_I	171_Y	0.550	0.64
105_S	146_N	0.550	0.64
32_F	169_A	0.550	0.64
111_D	295_A	0.550	0.64
219_I	249_F	0.550	0.64
402_I	441_F	0.548	0.64
440_N	443_I	0.547	0.64
288_I	308_H	0.547	0.64
92_V	144_I	0.547	0.64
361_R	406_I	0.546	0.64
143_N	154_T	0.544	0.64
234_N	309_N	0.543	0.63
174_L	177_V	0.543	0.63
80_D	133_G	0.542	0.63
375_S	380_L	0.541	0.63
106_D	146_N	0.540	0.63
41_R	44_F	0.540	0.63
259_V	285_V	0.540	0.63
67_L	136_L	0.539	0.63
362_V	428_V	0.539	0.63
287_S	386_L	0.538	0.63
181_N	188_E	0.538	0.63
57_I	287_S	0.537	0.63
83_V	86_Q	0.536	0.62
26_D	385_K	0.535	0.62
110_A	178_I	0.535	0.62
115_R	132_E	0.535	0.62
10_L	56_I	0.534	0.62
220_M	256_A	0.534	0.62
45_D	166_D	0.533	0.62
36_D	159_K	0.533	0.62
278_S	282_M	0.533	0.62
364_R	437_G	0.532	0.62
98_Y	101_V	0.531	0.62
16_E	20_E	0.531	0.62
137_L	140_K	0.531	0.62
93_D	138_S	0.529	0.61
171_Y	287_S	0.529	0.61
328_S	361_R	0.528	0.61
151_S	185_K	0.528	0.61
81_K	117_R	0.527	0.61
30_I	35_G	0.527	0.61
237_L	274_I	0.526	0.61
108_L	173_G	0.525	0.61
176_F	220_M	0.524	0.61
430_G	437_G	0.523	0.61
351_V	373_G	0.523	0.61
94_D	98_Y	0.522	0.60
240_R	282_M	0.521	0.60
356_G	373_G	0.520	0.60
109_I	114_I	0.520	0.60
74_I	80_D	0.520	0.60
350_V	374_V	0.519	0.60
141_G	228_V	0.516	0.59
107_I	126_V	0.516	0.59
187_K	215_E	0.516	0.59
225_D	256_A	0.516	0.59
297_G	300_P	0.514	0.59
402_I	429_G	0.513	0.59
141_G	229_E	0.513	0.59
363_S	371_I	0.512	0.59
407_D	411_K	0.512	0.59
380_L	430_G	0.511	0.59
76_V	136_L	0.511	0.59
261_T	277_I	0.511	0.59
329_E	444_V	0.510	0.59
68_G	138_S	0.509	0.58
340_A	426_V	0.509	0.58
14_S	46_L	0.509	0.58
111_D	225_D	0.509	0.58
58_V	174_L	0.508	0.58
119_K	122_A	0.508	0.58
14_S	296_I	0.507	0.58
218_G	386_L	0.507	0.58
247_R	284_G	0.506	0.58
388_Y	429_G	0.505	0.58
82_I	85_S	0.505	0.58
220_M	259_V	0.505	0.58
141_G	178_I	0.505	0.58
68_G	85_S	0.505	0.58
236_P	275_I	0.505	0.58
213_V	251_K	0.503	0.58
32_F	37_E	0.502	0.57
348_V	425_I	0.502	0.57
281_I	331_D	0.501	0.57
230_T	234_N	0.500	0.57
92_V	97_F	0.500	0.57

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3gr4A	4	0.9889	100	0.16	Contact Map
2e28A	3	0.9978	100	0.165	Contact Map
1a3wA	3	0.9823	100	0.167	Contact Map
3gg8A	3	0.9845	100	0.168	Contact Map
3t05A	3	0.9956	100	0.169	Contact Map
3khdA	3	0.9889	100	0.172	Contact Map
1e0tA	3	0.9358	100	0.174	Contact Map
4kctB	3	0.9889	100	0.192	Contact Map
4drsA	3	0.9668	100	0.202	Contact Map
3qtgA	3	0.9491	100	0.204	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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