Q97ZD0 - SULSO - GREMLIN Contacts

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Q97ZD0 - Glucan 1,4 alpha glucosidase (Glucoamylase)

UniProt:	Q97ZD0	Sequences: MRVSSIGNGRMLINFDEKGRIVDIYYPYIGMENQTSGNPIRLAIWDKDKKVASLDEDWETTVLYIDEANMVEIRSDVKELGLSLLSYNFLDSDDPIYMSIVKIANNENNSRNIKVFFIHDINLYSNPFGDTAFYDPLSLSIIHYKSKRYLAFKVFTTVSTLSEYNIGKGDLIGDIYDGNLGLNGIENGDVNSSMGIEINIDPNSYLKLYYVIVADRNLEGLRQKIRKINFANVETSFTLTYMFWRNWLKKNKLFRNNLMQDIKRVYDVSLFVIRNHMDVNGSIIASSDFSFVKIYGDSYQYCWPRDAAIAAYALDLAGYKELALKHFQFISNIANSEGFLYHKYNPNTTLASSWHPWYYKGKRIYPIQEDETALEVWAIASHYEKYEDIDEILPLYKKFVKPALKFMMSFMEEGLPKPSFDLWEERYGIHIYTVSTVYGALTKGAKLAYDVGDEILSEDLSDTSGLLKGMVLKRMTYNGRFVRRIDEENNQDLTVDSSLYAPFFFGLVNANDKIMINTINEIESRLTVNGGIIRYENDMYQRRKKQPNPWIITTLWLSEYYATINDKNKANEYIKWVINRALPTGFLPEQVDPETFEPTSVTPLVWSHAEFIIAINKLLNHI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	622 (568)
Sequences:	782 (626)
Seq/√Len:	26.3

SULSO - Q97ZD0 Q97VY0 Q97V81 Q97V93

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
449_Y	461_S	7.925	1.00
270_L	317_A	5.325	1.00
174_D	177_D	4.886	1.00
269_S	608_H	4.705	1.00
495_V	521_E	4.509	1.00
425_E	535_Y	4.155	1.00
21_I	97_Y	3.856	1.00
69_N	275_N	3.855	1.00
408_M	444_G	3.738	1.00
476_T	514_I	3.730	1.00
555_L	577_V	3.244	1.00
69_N	271_F	3.206	1.00
558_S	614_A	3.206	1.00
192_S	196_I	3.164	1.00
63_L	72_E	3.103	1.00
513_K	517_N	3.099	1.00
502_P	515_M	2.889	1.00
480_R	483_R	2.877	1.00
62_V	73_I	2.826	1.00
192_S	198_I	2.808	1.00
315_D	382_H	2.807	1.00
442_T	461_S	2.785	1.00
578_I	611_F	2.721	0.99
104_A	205_Y	2.710	0.99
193_S	196_I	2.693	0.99
89_F	237_F	2.669	0.99
479_G	517_N	2.660	0.99
495_V	525_R	2.604	0.99
435_S	502_P	2.595	0.99
192_S	197_E	2.503	0.99
74_R	85_L	2.459	0.99
415_L	467_L	2.459	0.99
403_A	406_F	2.458	0.99
559_E	614_A	2.436	0.99
73_I	88_N	2.424	0.99
152_F	212_I	2.419	0.99
276_H	605_V	2.390	0.99
68_A	241_Y	2.353	0.98
193_S	197_E	2.348	0.98
445_A	464_S	2.344	0.98
30_G	346_P	2.260	0.98
566_D	569_K	2.249	0.98
559_E	613_I	2.228	0.98
497_S	522_I	2.215	0.98
268_V	271_F	2.188	0.97
70_M	237_F	2.139	0.97
266_Y	612_I	2.137	0.97
405_K	460_L	2.128	0.97
462_D	466_L	2.086	0.97
508_V	515_M	2.048	0.96
432_Y	498_S	2.025	0.96
194_M	198_I	2.018	0.96
265_V	578_I	1.988	0.95
495_V	522_I	1.974	0.95
552_I	607_S	1.969	0.95
519_I	564_I	1.958	0.95
408_M	441_L	1.955	0.95
525_R	536_E	1.953	0.95
500_Y	519_I	1.947	0.95
453_D	456_L	1.928	0.95
403_A	407_M	1.908	0.94
201_D	204_S	1.905	0.94
67_E	245_R	1.885	0.94
177_D	181_G	1.885	0.94
273_I	605_V	1.875	0.94
61_T	74_R	1.870	0.94
431_I	475_M	1.863	0.94
88_N	99_S	1.863	0.94
89_F	98_M	1.860	0.93
470_M	474_R	1.850	0.93
481_F	514_I	1.849	0.93
481_F	508_V	1.846	0.93
215_D	224_K	1.830	0.93
531_G	549_P	1.824	0.93
170_D	175_I	1.813	0.93
601_V	604_L	1.776	0.92
406_F	412_E	1.766	0.92
70_M	241_Y	1.764	0.91
590_Q	604_L	1.763	0.91
189_D	192_S	1.742	0.91
100_I	209_Y	1.734	0.91
102_K	205_Y	1.720	0.90
527_T	532_I	1.704	0.90
472_L	508_V	1.702	0.90
472_L	481_F	1.700	0.90
284_I	287_S	1.685	0.89
193_S	198_I	1.677	0.89
190_V	193_S	1.670	0.89
53_S	56_E	1.662	0.89
235_T	239_L	1.661	0.89
190_V	197_E	1.661	0.89
404_L	407_M	1.655	0.89
275_N	287_S	1.643	0.88
268_V	585_G	1.637	0.88
272_V	510_A	1.632	0.88
266_Y	317_A	1.627	0.88
102_K	207_K	1.626	0.88
481_F	486_D	1.625	0.88
247_W	274_R	1.616	0.87
354_W	428_G	1.615	0.87
399_F	403_A	1.613	0.87
468_K	472_L	1.591	0.87
345_N	350_L	1.590	0.86
513_K	516_I	1.590	0.86
550_W	604_L	1.588	0.86
265_V	587_L	1.585	0.86
531_G	554_T	1.575	0.86
345_N	349_T	1.564	0.86
72_E	85_L	1.557	0.85
247_W	322_L	1.546	0.85
457_S	461_S	1.532	0.84
480_R	521_E	1.531	0.84
590_Q	606_W	1.529	0.84
557_L	561_Y	1.528	0.84
526_L	608_H	1.527	0.84
65_I	241_Y	1.525	0.84
169_G	173_G	1.516	0.84
187_N	190_V	1.514	0.84
191_N	196_I	1.514	0.84
171_L	175_I	1.514	0.84
114_K	199_N	1.511	0.84
100_I	207_K	1.501	0.83
476_T	517_N	1.496	0.83
283_I	310_A	1.479	0.82
561_Y	566_D	1.476	0.82
554_T	580_R	1.472	0.82
434_V	471_V	1.470	0.82
414_G	417_K	1.468	0.82
119_H	210_Y	1.465	0.82
124_Y	128_F	1.460	0.81
476_T	479_G	1.452	0.81
435_S	471_V	1.450	0.81
370_D	378_A	1.446	0.81
120_D	193_S	1.444	0.81
615_I	618_L	1.441	0.80
242_M	246_N	1.440	0.80
480_R	484_R	1.438	0.80
216_R	220_G	1.437	0.80
116_F	180_L	1.437	0.80
310_A	605_V	1.433	0.80
574_I	615_I	1.432	0.80
438_Y	471_V	1.430	0.80
65_I	72_E	1.420	0.79
270_L	607_S	1.414	0.79
173_G	176_Y	1.410	0.79
602_T	605_V	1.405	0.79
556_W	607_S	1.402	0.79
190_V	196_I	1.401	0.78
101_V	208_L	1.396	0.78
562_A	567_K	1.376	0.77
57_D	79_E	1.370	0.77
338_G	354_W	1.361	0.76
28_Y	347_N	1.353	0.76
439_G	495_V	1.353	0.76
582_L	602_T	1.346	0.76
299_Y	589_E	1.341	0.75
21_I	56_E	1.336	0.75
523_E	569_K	1.312	0.74
431_I	499_L	1.310	0.74
194_M	197_E	1.303	0.73
601_V	609_A	1.298	0.73
406_F	411_M	1.284	0.72
471_V	507_L	1.283	0.72
30_G	43_A	1.278	0.72
142_I	151_A	1.276	0.72
341_Y	344_Y	1.266	0.71
603_P	608_H	1.248	0.70
438_Y	507_L	1.232	0.69
23_D	33_N	1.226	0.68
569_K	572_E	1.222	0.68
516_I	564_I	1.221	0.68
67_E	267_D	1.219	0.68
288_D	343_K	1.218	0.68
524_S	595_T	1.211	0.67
516_I	520_N	1.210	0.67
44_I	48_D	1.210	0.67
339_F	372_T	1.206	0.67
510_A	581_A	1.199	0.67
404_L	441_L	1.196	0.66
398_K	402_P	1.193	0.66
527_T	530_G	1.192	0.66
191_N	457_S	1.192	0.66
401_K	405_K	1.190	0.66
146_S	259_M	1.187	0.66
303_W	306_D	1.186	0.66
390_D	394_P	1.185	0.66
274_R	322_L	1.184	0.66
373_A	440_A	1.180	0.65
276_H	287_S	1.176	0.65
368_Q	550_W	1.173	0.65
132_A	192_S	1.168	0.65
368_Q	604_L	1.166	0.64
466_L	524_S	1.165	0.64
369_E	437_V	1.159	0.64
63_L	67_E	1.157	0.64
285_A	424_E	1.153	0.64
345_N	433_T	1.151	0.63
551_I	577_V	1.151	0.63
481_F	484_R	1.149	0.63
196_I	199_N	1.148	0.63
50_K	53_S	1.145	0.63
329_F	344_Y	1.142	0.63
501_A	504_F	1.142	0.63
69_N	73_I	1.140	0.63
338_G	368_Q	1.139	0.63
445_A	457_S	1.138	0.63
235_T	238_T	1.137	0.62
27_P	30_G	1.136	0.62
496_D	534_R	1.136	0.62
141_I	214_A	1.135	0.62
380_A	383_Y	1.129	0.62
192_S	200_I	1.128	0.62
24_I	40_I	1.124	0.62
473_K	488_E	1.123	0.61
164_Y	167_G	1.121	0.61
384_E	570_A	1.120	0.61
463_T	466_L	1.120	0.61
397_K	400_V	1.118	0.61
468_K	508_V	1.115	0.61
21_I	516_I	1.114	0.61
115_V	148_R	1.111	0.61
226_R	612_I	1.111	0.61
187_N	192_S	1.111	0.61
570_A	618_L	1.110	0.61
270_L	612_I	1.106	0.60
276_H	300_Q	1.106	0.60
391_E	395_L	1.104	0.60
531_G	580_R	1.103	0.60
600_S	604_L	1.103	0.60
187_N	196_I	1.100	0.60
323_A	565_N	1.097	0.60
225_I	232_N	1.097	0.60
181_G	473_K	1.093	0.59
245_R	267_D	1.092	0.59
342_H	354_W	1.090	0.59
87_Y	210_Y	1.086	0.59
62_V	88_N	1.082	0.59
25_Y	371_E	1.071	0.58
192_S	195_G	1.068	0.58
584_T	588_P	1.068	0.58
550_W	590_Q	1.060	0.57
264_R	268_V	1.056	0.57
401_K	406_F	1.055	0.57
373_A	376_V	1.055	0.57
542_R	548_N	1.052	0.56
380_A	436_T	1.045	0.56
503_F	560_Y	1.041	0.56
214_A	375_E	1.041	0.56
408_M	411_M	1.039	0.55
311_A	554_T	1.037	0.55
169_G	172_I	1.037	0.55
601_V	606_W	1.033	0.55
428_G	606_W	1.032	0.55
401_K	453_D	1.028	0.55
404_L	457_S	1.028	0.55
170_D	173_G	1.027	0.55
131_T	463_T	1.026	0.54
610_E	613_I	1.024	0.54
87_Y	100_I	1.023	0.54
515_M	575_K	1.017	0.54
42_L	104_A	1.017	0.54
258_L	261_D	1.012	0.53
233_V	314_L	1.009	0.53
216_R	219_E	1.003	0.53
428_G	604_L	1.001	0.53
457_S	570_A	0.997	0.52
80_L	507_L	0.997	0.52
247_W	319_Y	0.996	0.52
272_V	586_F	0.988	0.52
114_K	197_E	0.987	0.52
171_L	174_D	0.983	0.51
412_E	463_T	0.975	0.51
162_S	165_N	0.970	0.50
75_S	86_S	0.967	0.50
170_D	174_D	0.966	0.50
118_I	193_S	0.965	0.50
523_E	561_Y	0.964	0.50
439_G	442_T	0.961	0.50
35_T	286_S	0.960	0.50
354_W	538_D	0.959	0.50
285_A	423_W	0.958	0.49
64_Y	271_F	0.957	0.49
276_H	371_E	0.955	0.49
78_K	234_E	0.952	0.49
354_W	606_W	0.951	0.49
25_Y	289_F	0.951	0.49
342_H	368_Q	0.949	0.49
516_I	522_I	0.949	0.49
68_A	496_D	0.945	0.48
299_Y	424_E	0.943	0.48
145_K	148_R	0.941	0.48
213_V	441_L	0.939	0.48
201_D	524_S	0.938	0.48
481_F	485_I	0.937	0.48
513_K	564_I	0.932	0.48
523_E	557_L	0.930	0.47
428_G	538_D	0.929	0.47
41_R	45_W	0.929	0.47
500_Y	503_F	0.924	0.47
140_S	153_K	0.923	0.47
467_L	522_I	0.923	0.47
102_K	114_K	0.922	0.47
343_K	372_T	0.921	0.47
435_S	538_D	0.918	0.46
235_T	449_Y	0.917	0.46
547_P	550_W	0.915	0.46
332_N	403_A	0.915	0.46
272_V	546_Q	0.912	0.46
66_D	264_R	0.910	0.46
557_L	573_Y	0.910	0.46
269_S	283_I	0.910	0.46
330_I	375_E	0.908	0.46
179_N	452_G	0.905	0.46
34_Q	53_S	0.903	0.45
342_H	590_Q	0.902	0.45
520_N	524_S	0.901	0.45
497_S	591_V	0.901	0.45
368_Q	606_W	0.898	0.45
174_D	182_L	0.896	0.45
552_I	610_E	0.896	0.45
288_D	355_H	0.893	0.45
265_V	311_A	0.891	0.44
62_V	275_N	0.890	0.44
23_D	288_D	0.889	0.44
338_G	540_Y	0.887	0.44
272_V	608_H	0.886	0.44
334_A	593_P	0.886	0.44
302_C	433_T	0.886	0.44
141_I	581_A	0.884	0.44
75_S	82_L	0.882	0.44
444_G	460_L	0.881	0.44
428_G	590_Q	0.881	0.44
77_V	82_L	0.881	0.44
247_W	270_L	0.880	0.44
484_R	487_E	0.877	0.43
215_D	335_N	0.877	0.43
171_L	181_G	0.877	0.43
273_I	612_I	0.876	0.43
376_V	440_A	0.873	0.43
574_I	618_L	0.872	0.43
25_Y	276_H	0.871	0.43
571_N	575_K	0.871	0.43
292_V	298_S	0.870	0.43
402_P	615_I	0.869	0.43
288_D	601_V	0.867	0.43
352_S	355_H	0.867	0.43
177_D	180_L	0.866	0.43
370_D	550_W	0.865	0.43
530_G	576_W	0.863	0.42
147_K	152_F	0.861	0.42
338_G	370_D	0.860	0.42
403_A	408_M	0.860	0.42
157_T	216_R	0.859	0.42
43_A	51_V	0.859	0.42
122_N	130_D	0.859	0.42
458_E	462_D	0.858	0.42
574_I	578_I	0.858	0.42
48_D	53_S	0.856	0.42
343_K	590_Q	0.855	0.42
368_Q	590_Q	0.855	0.42
135_D	139_L	0.853	0.42
138_S	235_T	0.852	0.42
531_G	550_W	0.849	0.41
161_L	166_I	0.849	0.41
160_T	163_E	0.847	0.41
413_E	459_D	0.847	0.41
263_K	267_D	0.847	0.41
459_D	463_T	0.846	0.41
392_I	409_S	0.846	0.41
120_D	166_I	0.846	0.41
119_H	123_L	0.845	0.41
400_V	406_F	0.845	0.41
565_N	586_F	0.844	0.41
404_L	444_G	0.841	0.41
552_I	606_W	0.841	0.41
531_G	596_F	0.840	0.41
217_N	516_I	0.839	0.41
393_L	451_V	0.838	0.41
287_S	300_Q	0.838	0.41
173_G	191_N	0.838	0.41
125_S	369_E	0.836	0.40
347_N	351_A	0.835	0.40
301_Y	353_S	0.835	0.40
61_T	264_R	0.834	0.40
540_Y	550_W	0.834	0.40
25_Y	286_S	0.828	0.40
463_T	467_L	0.828	0.40
304_P	354_W	0.827	0.40
302_C	590_Q	0.826	0.40
323_A	570_A	0.826	0.40
366_P	371_E	0.823	0.40
158_V	164_Y	0.823	0.40
589_E	603_P	0.823	0.40
401_K	404_L	0.823	0.40
606_W	609_A	0.820	0.39
24_I	607_S	0.820	0.39
216_R	466_L	0.818	0.39
219_E	470_M	0.817	0.39
272_V	605_V	0.817	0.39
273_I	382_H	0.816	0.39
103_I	400_V	0.816	0.39
59_E	64_Y	0.814	0.39
62_V	71_V	0.814	0.39
314_L	552_I	0.813	0.39
141_I	194_M	0.812	0.39
429_I	439_G	0.812	0.39
62_V	432_Y	0.809	0.39
372_T	606_W	0.805	0.38
368_Q	428_G	0.802	0.38
475_M	485_I	0.801	0.38
311_A	588_P	0.800	0.38
87_Y	237_F	0.800	0.38
117_F	121_I	0.799	0.38
163_E	166_I	0.795	0.38
477_Y	480_R	0.794	0.38
197_E	220_G	0.792	0.37
471_V	568_N	0.791	0.37
429_I	434_V	0.789	0.37
262_I	615_I	0.787	0.37
219_E	454_E	0.783	0.37
480_R	485_I	0.781	0.37
514_I	522_I	0.779	0.36
141_I	516_I	0.779	0.36
479_G	514_I	0.776	0.36
610_E	615_I	0.775	0.36
422_L	556_W	0.775	0.36
334_A	340_L	0.775	0.36
339_F	367_I	0.775	0.36
250_K	321_E	0.774	0.36
450_D	511_N	0.772	0.36
469_G	513_K	0.772	0.36
291_F	378_A	0.772	0.36
555_L	587_L	0.767	0.36
532_I	548_N	0.763	0.35
470_M	485_I	0.763	0.35
586_F	602_T	0.762	0.35
262_I	578_I	0.762	0.35
64_Y	68_A	0.762	0.35
516_I	519_I	0.762	0.35
434_V	475_M	0.761	0.35
122_N	127_P	0.758	0.35
146_S	153_K	0.758	0.35
238_T	241_Y	0.756	0.35
276_H	286_S	0.755	0.35
372_T	428_G	0.755	0.35
559_E	617_K	0.754	0.35
354_W	368_Q	0.754	0.35
354_W	370_D	0.754	0.35
103_I	113_I	0.753	0.35
387_E	485_I	0.752	0.35
399_F	407_M	0.752	0.35
499_L	518_T	0.751	0.35
432_Y	497_S	0.751	0.35
30_G	612_I	0.750	0.35
380_A	447_L	0.749	0.34
538_D	609_A	0.745	0.34
179_N	235_T	0.745	0.34
341_Y	375_E	0.745	0.34
23_D	600_S	0.743	0.34
23_D	291_F	0.740	0.34
289_F	337_E	0.740	0.34
236_S	379_I	0.739	0.34
307_A	326_H	0.738	0.34
372_T	419_S	0.738	0.34
515_M	560_Y	0.737	0.34
124_Y	148_R	0.737	0.34
435_S	439_G	0.735	0.34
432_Y	501_A	0.734	0.33
65_I	237_F	0.734	0.33
336_S	511_N	0.733	0.33
299_Y	338_G	0.733	0.33
547_P	590_Q	0.733	0.33
336_S	409_S	0.732	0.33
379_I	382_H	0.732	0.33
270_L	347_N	0.732	0.33
412_E	415_L	0.731	0.33
368_Q	540_Y	0.731	0.33
27_P	318_G	0.731	0.33
415_L	437_V	0.730	0.33
51_V	56_E	0.730	0.33
439_G	443_K	0.730	0.33
34_Q	119_H	0.729	0.33
20_R	287_S	0.729	0.33
85_L	102_K	0.729	0.33
273_I	314_L	0.729	0.33
514_I	518_T	0.729	0.33
151_A	233_V	0.728	0.33
49_K	178_G	0.726	0.33
117_F	210_Y	0.726	0.33
31_M	247_W	0.726	0.33
416_P	464_S	0.725	0.33
101_V	346_P	0.724	0.33
336_S	487_E	0.724	0.33
448_A	451_V	0.723	0.33
172_I	176_Y	0.723	0.33
258_L	618_L	0.723	0.33
605_V	615_I	0.723	0.33
262_I	266_Y	0.723	0.33
42_L	273_I	0.723	0.33
534_R	603_P	0.721	0.33
399_F	406_F	0.720	0.33
290_S	504_F	0.720	0.33
342_H	604_L	0.719	0.32
437_V	467_L	0.718	0.32
613_I	617_K	0.718	0.32
141_I	192_S	0.718	0.32
246_N	250_K	0.718	0.32
19_G	91_D	0.717	0.32
297_D	374_L	0.716	0.32
124_Y	146_S	0.714	0.32
453_D	612_I	0.714	0.32
288_D	352_S	0.714	0.32
510_A	587_L	0.714	0.32
288_D	600_S	0.713	0.32
469_G	516_I	0.712	0.32
456_L	497_S	0.710	0.32
266_Y	270_L	0.710	0.32
115_V	319_Y	0.709	0.32
19_G	73_I	0.709	0.32
550_W	606_W	0.707	0.32
140_S	152_F	0.706	0.32
144_Y	154_V	0.703	0.31
238_T	249_K	0.703	0.31
117_F	131_T	0.702	0.31
135_D	142_I	0.701	0.31
477_Y	482_V	0.701	0.31
170_D	176_Y	0.701	0.31
191_N	328_Q	0.699	0.31
138_S	524_S	0.699	0.31
186_E	440_A	0.698	0.31
201_D	473_K	0.697	0.31
63_L	449_Y	0.697	0.31
112_N	183_N	0.697	0.31
391_E	398_K	0.697	0.31
21_I	488_E	0.696	0.31
392_I	399_F	0.694	0.31
416_P	466_L	0.694	0.31
131_T	473_K	0.694	0.31
180_L	439_G	0.693	0.31
380_A	442_T	0.693	0.31
308_A	613_I	0.692	0.31
269_S	367_I	0.692	0.31
483_R	486_D	0.691	0.31
170_D	181_G	0.690	0.31
548_N	590_Q	0.687	0.30
318_G	444_G	0.684	0.30
61_T	76_D	0.684	0.30
552_I	580_R	0.684	0.30
557_L	592_D	0.683	0.30
411_M	466_L	0.683	0.30
96_I	228_I	0.683	0.30
390_D	399_F	0.682	0.30
81_G	104_A	0.681	0.30
471_V	475_M	0.681	0.30
259_M	263_K	0.681	0.30
92_S	346_P	0.680	0.30
534_R	589_E	0.679	0.30
411_M	559_E	0.678	0.30
191_N	198_I	0.677	0.30
291_F	300_Q	0.677	0.30
604_L	609_A	0.676	0.30
441_L	498_S	0.676	0.30
275_N	297_D	0.674	0.30
23_D	289_F	0.674	0.30
112_N	199_N	0.673	0.30
493_L	529_N	0.673	0.30
251_N	270_L	0.672	0.29
286_S	508_V	0.670	0.29
142_I	146_S	0.670	0.29
515_M	557_L	0.669	0.29
554_T	577_V	0.668	0.29
259_M	469_G	0.668	0.29
225_I	470_M	0.667	0.29
129_G	607_S	0.666	0.29
74_R	577_V	0.666	0.29
286_S	555_L	0.665	0.29
478_N	595_T	0.665	0.29
505_F	522_I	0.664	0.29
449_Y	513_K	0.664	0.29
247_W	366_P	0.664	0.29
287_S	310_A	0.662	0.29
436_T	440_A	0.661	0.29
97_Y	456_L	0.661	0.29
522_I	549_P	0.660	0.29
23_D	421_D	0.660	0.29
306_D	496_D	0.660	0.29
116_F	197_E	0.660	0.29
57_D	60_T	0.659	0.29
425_E	540_Y	0.658	0.29
484_R	612_I	0.654	0.28
149_Y	191_N	0.653	0.28
207_K	591_V	0.652	0.28
68_A	313_A	0.651	0.28
396_Y	399_F	0.649	0.28
269_S	535_Y	0.649	0.28
320_K	388_D	0.648	0.28
368_Q	609_A	0.647	0.28
542_R	590_Q	0.646	0.28
290_S	592_D	0.644	0.28
33_N	298_S	0.640	0.28
371_E	419_S	0.640	0.28
78_K	572_E	0.640	0.28
246_N	321_E	0.639	0.27
168_K	172_I	0.639	0.27
66_D	242_M	0.638	0.27
384_E	446_K	0.638	0.27
371_E	601_V	0.637	0.27
167_G	418_P	0.636	0.27
155_F	522_I	0.635	0.27
174_D	180_L	0.635	0.27
66_D	245_R	0.635	0.27
434_V	604_L	0.634	0.27
139_L	473_K	0.634	0.27
244_W	518_T	0.633	0.27
462_D	469_G	0.632	0.27
324_L	388_D	0.632	0.27
393_L	588_P	0.631	0.27
587_L	604_L	0.630	0.27
283_I	573_Y	0.630	0.27
216_R	245_R	0.629	0.27
514_I	517_N	0.629	0.27
509_N	516_I	0.628	0.27
518_T	553_T	0.628	0.27
19_G	298_S	0.627	0.27
582_L	597_E	0.627	0.27
338_G	403_A	0.626	0.27
115_V	224_K	0.626	0.27
402_P	406_F	0.626	0.27
370_D	606_W	0.626	0.27
54_L	80_L	0.623	0.27
251_N	615_I	0.623	0.27
571_N	607_S	0.623	0.27
106_N	220_G	0.622	0.26
232_N	236_S	0.621	0.26
432_Y	496_D	0.620	0.26
288_D	553_T	0.620	0.26
132_A	150_L	0.619	0.26
234_E	238_T	0.618	0.26
68_A	271_F	0.616	0.26
404_L	412_E	0.616	0.26
299_Y	306_D	0.616	0.26
285_A	306_D	0.615	0.26
235_T	509_N	0.615	0.26
421_D	606_W	0.614	0.26
112_N	191_N	0.614	0.26
76_D	106_N	0.614	0.26
312_Y	340_L	0.614	0.26
276_H	343_K	0.614	0.26
502_P	508_V	0.613	0.26
98_M	252_K	0.612	0.26
95_P	201_D	0.610	0.26
370_D	609_A	0.609	0.26
49_K	286_S	0.609	0.26
140_S	143_H	0.607	0.26
162_S	173_G	0.606	0.26
393_L	399_F	0.606	0.26
207_K	272_V	0.605	0.26
23_D	541_Q	0.605	0.26
425_E	432_Y	0.604	0.25
519_I	573_Y	0.603	0.25
324_L	454_E	0.602	0.25
381_S	436_T	0.602	0.25
97_Y	565_N	0.600	0.25
334_A	352_S	0.598	0.25
159_S	203_N	0.598	0.25
234_E	243_F	0.597	0.25
21_I	115_V	0.597	0.25
499_L	558_S	0.597	0.25
532_I	557_L	0.596	0.25
374_L	410_F	0.595	0.25
202_P	407_M	0.595	0.25
380_A	446_K	0.595	0.25
284_I	501_A	0.595	0.25
338_G	606_W	0.594	0.25
104_A	454_E	0.594	0.25
479_G	484_R	0.593	0.25
297_D	343_K	0.593	0.25
374_L	540_Y	0.591	0.25
333_I	585_G	0.591	0.25
541_Q	592_D	0.590	0.25
273_I	502_P	0.590	0.25
483_R	522_I	0.589	0.25
169_G	181_G	0.589	0.25
274_R	293_K	0.588	0.25
530_G	549_P	0.587	0.24
507_L	543_R	0.587	0.24
317_A	587_L	0.585	0.24
560_Y	611_F	0.583	0.24
316_L	613_I	0.583	0.24
85_L	347_N	0.581	0.24
225_I	476_T	0.581	0.24
213_V	562_A	0.580	0.24
355_H	367_I	0.580	0.24
77_V	80_L	0.580	0.24
65_I	76_D	0.579	0.24
82_L	115_V	0.578	0.24
230_F	409_S	0.577	0.24
23_D	378_A	0.577	0.24
380_A	443_K	0.577	0.24
116_F	428_G	0.576	0.24
500_Y	557_L	0.576	0.24
125_S	434_V	0.576	0.24
219_E	566_D	0.574	0.24
163_E	167_G	0.574	0.24
484_R	498_S	0.573	0.24
262_I	611_F	0.573	0.24
61_T	203_N	0.572	0.24
155_F	226_R	0.571	0.24
52_A	101_V	0.571	0.24
406_F	413_E	0.571	0.24
482_V	488_E	0.571	0.24
422_L	504_F	0.571	0.24
120_D	552_I	0.570	0.24
510_A	563_T	0.569	0.24
43_A	296_G	0.569	0.24
307_A	537_N	0.569	0.24
531_G	576_W	0.569	0.24
85_L	95_P	0.569	0.24
157_T	516_I	0.569	0.24
67_E	447_L	0.568	0.23
75_S	344_Y	0.567	0.23
566_D	619_L	0.566	0.23
342_H	372_T	0.565	0.23
371_E	604_L	0.565	0.23
400_V	407_M	0.564	0.23
465_G	545_K	0.564	0.23
399_F	404_L	0.564	0.23
244_W	565_N	0.564	0.23
269_S	286_S	0.563	0.23
555_L	558_S	0.563	0.23
215_D	404_L	0.563	0.23
519_I	577_V	0.562	0.23
406_F	410_F	0.562	0.23
332_N	405_K	0.561	0.23
25_Y	373_A	0.561	0.23
94_D	227_K	0.559	0.23
472_L	475_M	0.558	0.23
51_V	119_H	0.558	0.23
282_S	559_E	0.557	0.23
306_D	589_E	0.556	0.23
150_L	463_T	0.556	0.23
353_S	407_M	0.554	0.23
260_Q	615_I	0.553	0.23
101_V	246_N	0.552	0.23
323_A	495_V	0.551	0.23
86_S	99_S	0.551	0.23
69_N	433_T	0.551	0.23
23_D	345_N	0.550	0.23
50_K	79_E	0.550	0.23
447_L	451_V	0.549	0.22
73_I	287_S	0.549	0.22
85_L	283_I	0.548	0.22
22_V	90_L	0.548	0.22
425_E	550_W	0.548	0.22
296_G	366_P	0.547	0.22
149_Y	390_D	0.547	0.22
568_N	585_G	0.546	0.22
425_E	541_Q	0.546	0.22
194_M	457_S	0.546	0.22
424_E	603_P	0.545	0.22
219_E	493_L	0.545	0.22
419_S	601_V	0.545	0.22
342_H	350_L	0.545	0.22
234_E	249_K	0.544	0.22
198_I	471_V	0.541	0.22
315_D	327_F	0.541	0.22
444_G	448_A	0.540	0.22
299_Y	496_D	0.540	0.22
305_R	534_R	0.539	0.22
251_N	319_Y	0.539	0.22
70_M	242_M	0.538	0.22
48_D	258_L	0.538	0.22
231_A	234_E	0.538	0.22
511_N	516_I	0.537	0.22
48_D	563_T	0.537	0.22
308_A	426_R	0.536	0.22
376_V	460_L	0.536	0.22
515_M	519_I	0.535	0.22
150_L	250_K	0.535	0.22
235_T	263_K	0.533	0.22
342_H	606_W	0.533	0.22
335_N	552_I	0.532	0.22
519_I	557_L	0.532	0.22
353_S	371_E	0.532	0.22
558_S	577_V	0.532	0.22
432_Y	505_F	0.531	0.22
50_K	55_D	0.531	0.22
235_T	328_Q	0.531	0.22
289_F	560_Y	0.530	0.22
334_A	374_L	0.529	0.21
462_D	575_K	0.528	0.21
192_S	199_N	0.527	0.21
400_V	448_A	0.527	0.21
247_W	585_G	0.527	0.21
259_M	262_I	0.526	0.21
376_V	421_D	0.525	0.21
448_A	452_G	0.524	0.21
237_F	241_Y	0.523	0.21
297_D	355_H	0.522	0.21
346_P	617_K	0.522	0.21
482_V	487_E	0.522	0.21
284_I	465_G	0.521	0.21
421_D	604_L	0.520	0.21
21_I	68_A	0.520	0.21
157_T	264_R	0.520	0.21
227_K	249_K	0.519	0.21
95_P	233_V	0.519	0.21
24_I	212_I	0.519	0.21
87_Y	98_M	0.519	0.21
271_F	308_A	0.519	0.21
119_H	152_F	0.519	0.21
461_S	469_G	0.518	0.21
59_E	223_Q	0.518	0.21
475_M	481_F	0.518	0.21
301_Y	371_E	0.517	0.21
128_F	618_L	0.517	0.21
394_P	451_V	0.517	0.21
235_T	575_K	0.517	0.21
245_R	321_E	0.517	0.21
189_D	197_E	0.517	0.21
73_I	276_H	0.516	0.21
65_I	68_A	0.516	0.21
30_G	355_H	0.515	0.21
354_W	587_L	0.515	0.21
550_W	600_S	0.513	0.21
85_L	530_G	0.513	0.21
551_I	587_L	0.512	0.21
322_L	367_I	0.511	0.21
498_S	501_A	0.511	0.21
66_D	493_L	0.511	0.21
272_V	314_L	0.511	0.21
73_I	297_D	0.511	0.21
350_L	377_W	0.510	0.21
379_I	599_T	0.510	0.21
299_Y	534_R	0.510	0.21
600_S	606_W	0.509	0.20
68_A	115_V	0.509	0.20
85_L	581_A	0.508	0.20
422_L	542_R	0.508	0.20
287_S	553_T	0.508	0.20
482_V	486_D	0.508	0.20
563_T	609_A	0.507	0.20
26_Y	212_I	0.506	0.20
104_A	404_L	0.505	0.20
334_A	399_F	0.505	0.20
70_M	610_E	0.504	0.20
298_S	345_N	0.503	0.20
524_S	568_N	0.502	0.20
469_G	583_P	0.502	0.20
158_V	329_F	0.501	0.20
106_N	373_A	0.500	0.20
230_F	524_S	0.500	0.20

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ulvA	1	0.9437	100	0.4	Contact Map
1lf6A	1	0.9389	100	0.445	Contact Map
2fbaA	1	0.619	100	0.577	Contact Map
2vn4A	1	0.5466	100	0.602	Contact Map
1gaiA	1	0.5434	100	0.607	Contact Map
1v7wA	2	0.9325	100	0.673	Contact Map
3p2cA	2	0.5916	100	0.701	Contact Map
3qryB	1	0.5772	100	0.704	Contact Map
3qt9A	1	0.5884	100	0.715	Contact Map
2p0vA	2	0.6013	100	0.717	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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